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Analyst
Journal Prestige (SJR): 1.249 ![]() Citation Impact (citeScore): 4 Number of Followers: 35 ![]() ISSN (Print) 0003-2654 - ISSN (Online) 1364-5528 Published by RSC ![]() |
- Greener Chemistry in Analytical Sciences - from Green Solvents to
Applications in Complex Matrices. Current Challenges and Future
Perspectives: A Critical Review-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00498H, Critical ReviewSlavica Ražić, Jelena Arsenijević, Svetlana Đogo Mračević, Jasmina Mušović, Tatjana Trtić-Petrović
More environmentally friendly solvents in analytical chemistry are almost inevitable in both sample preparation and analysis to meet the high standards of sustainable chemistry and human welfare. In this review...
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- NIR quantum dot construction of fluorescence anisotropy signal
amplification biosensor for sensitive rapid and separation-free detection
of dopamine in serum-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00590A, PaperJing Liu, Ming Chen, Zhi-Ling Zhang, Xuechuan Hong, Zili Yu, Zhi-Quan Tian
Dopamine (DA) is an important small-molecule neurotransmitter, which is closely related to the development of many neurological diseases and has received wide attention in the diagnosis of neurological diseases. Currently...
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- Designing a Nanothermometer using Gel-to-Liquid Phase Transition Property
of Hybrid Niosome-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00557G, CommunicationRonak Lazarus, Rupal Kothari, Kaja Sravani, Venkata Vamsi Krishna Venuganti, Amit Nag
The gel-to-liquid phase transition property of a hybrid niosome, which is made with a non-ionic surfactant, span 60 (S60), and triblock copolymer L64, is effectively utilized to design a nanothermometer...
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- A label-free electrochemical aptasensor based on Bi−Sb alloy materials
for potential POCT of HER-2-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00606A, PaperShanshan Shi, Liping Jia, Wei Zhang, Rongna Ma, Lei Shang, Xiao-jian Li, Huaiqing Zhao, Huaisheng Wang
As a prognostic biomarker for breast cancer, human epidermal growth factor receptor 2 (HER-2) is of crucial diagnostic value. Here, a label-free electrochemical aptasensor was established for the ultrasensitive detection...
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- A chemiluminescent sensor for imaging endogenous hydrogen polysulfides in
living system-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00507K, PaperHanqing Zhao, Fenghui Qi, Yanian Xiong, Jianzhong Lu
By constructing 2-(benzoylthio)benzoate and 2-fluoro-4-nitrobenzoate structure in the adamantylidene-dioxetane system, we designed and synthesized two novel chemiluminescent probes for detection of H2Sn from other RSS. Under the same conditions, the...
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- A one-stage deep learning based method for automatic analysis of
droplet-based digital PCR images-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00615H, PaperYuanyang Yao, Shuhao Zhao, Yan Liang, Fei Hu, Niancai Peng
Droplet-based dPCR offers many advantages over chip-based dPCR, such as lower processing cost, higher droplet density, higher throughput, while requiring less sample. However, the stochastic nature of droplet locations, uneven...
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- Nanoscale Bond-selective Imaging by Computational Fusion of Atomic Force
Microscopy and Coherent anti-Stokes Raman Scattering Microscopy-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00662J, PaperLe Wang, Ji-Xin Cheng
Vibrational microscopy based on coherent Raman scattering microscopy is a powerful tool for high-speed chemical imaging, but its lateral resolution is bound to the optical diffraction limit. On the other...
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- From Droplets to Ions: A Comprehensive and Consecutive Ion Formation
Modelling in Atmosphere Pressure Interface of Elec-trospray Ionization
Mass Spectrometry-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00607G, CommunicationXingliang He, Xing Guo , Mengfan Wu, Fulong Deng, Pengyu Zeng, Zhongjun Zhao, Yixiang Duan
Here we propose a novel ion formation simulation method of electrospray ionization (ESI) and atmosphere pressure interface (API). In this method, not the sheer particle trajectory, but the evolution of...
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- Integration of CRISPR Cas12a-assisted multicolor biosensor and
micropipette-tip enables visible point-of-care testing of foodborne Vibrio
vulnificus-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00714F, PaperZiyi Wang, Chutian Xu, Chengkai Yu, Zhenjun Si, Di Huang, Peijie Shen, Mengjun Fang, Zhinan Xu
Foodborne pathogens cause numerous food safety problems nowadays, and as a virulent bacterium falling under this category, Vibrio vulnificus (V. vulnificus) poses a huge threat to public health. The conventional...
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- Specific multiplexed detection of mRNA splice variants based on
size-coding DNA probes and universal PCR amplification-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00597F, PaperYuting Jia, Honghong Wang, Hui Wang, Fangfang Wang, Kejian Gao, Zhengping Li
Alternative messenger RNA (mRNA) splicing is a vital regulatory process during the gene expression of higher eukaryotes. The specific and sensitive quantification of disease-related mRNA splicing variants in the biological...
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- Production of Mixed Element Actinide Reference Particulates to Support
Nuclear Safeguards using THESEUS, an Aerosol-based Particulate Synthetic
Methodology-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D2AN01774A, PaperBenjamin E. Naes, Spencer M Scott, Abigail Waldron, Seth Lawson, Michael G. Bronikowski, Laken I. Gleaton, Ross Smith, Kimberly N. Wurth, Travis J. Tenner, Matthew S. Wellons
The THermally Evaporated Spray for Engineered Uniform particulateS (THESEUS) production platform was developed to generate highly uniform mixed actinide oxide particles. The particulate synthesis platform builds on previous efforts and...
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- Electrochemiluminescence immunosensor based on multipath signal catalytic
amplification integrated in Cu2+-PEI-Pt/AuNCs nanocomposite-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00721A, PaperHaijun Wang, Yuhang Song, Yaqin Chai, Ruo Yuan
Here, the nanocomposite of Cu2+-PEI-Pt/AuNCs with multipath signal catalytic amplification to peroxydisulfate-dissolved oxygen electrochemiluminescence (ECL) system was prepared to fabricate sensitive ECL immunosensor. Using polyethyleneimine (PEI), a linear polymer, as...
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- Digital image colorimetric detection of ceftazidime based on azo compound
formation on polyethyleneimine modified cotton sponge-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00563A, PaperLalitphan Hongtanee, Narong Praphairaksit, Fuangfa Unob
A novel colorimetric platform using cotton sponge modified with polyethyleneimine (PEI) was fabricated for the detection of ceftazidime through the diazotization and coupling reaction. In this work, cotton sponges were...
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- Red Emissive Carbon Nanostructure-Anchored Molecularly Imprinted Er-BTC
MOF: A Biosensor for Visual Anthrax Monitoring-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00865G, PaperKheibar Dashtian, Solmaz Norouzi, Fereshteh Amourizi , Rouholah Zare-Dorabei
Investigating effective fluorescence strategies for real-time monitoring of dipicolinic acid (DPA) is of paramount importance in safeguarding human health. Herein, we present the design of a desirable red emissive carbon...
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- Molecularly Imprinted Polymer Coating-Assisted CsPbBr3 Perovskite Quantum
Dots/TiO2 Inverse Opal Heterojunctions for the Photoelectrochemical
Detection of Cholesterol-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00504F, PaperXuan Wang, Fankai Lin, Xiaoyu Zhou, Yunfei Miao, Dongwei Feng, Peng Huang, Mingxing Ren, Lina Geng, Aiqin Luo, Yulin Deng
Photoelectrochemical sensors have outstanding advantages including high sensitivity and miniaturization for outdoor use. Recently, perovskite quantum dots have attracted significant attention due to their high photoluminescence quantum yield. Nonetheless, there...
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- Application of ATP-based bioluminescence technology in bacterial
detection:A Review-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00576C, Tutorial ReviewShitong Liu, Jinbin Zhao, Yulan Guo, Xueer Ma, Chunmeng Sun, Ming Cai, Yuyang Chi, Kun Xu
With the development of new technologies for rapid and high-throughput bacterial detection, ATP-based bioluminescence technology is making progress. Because live bacteria contain ATP, the number of bacteria is correlated with...
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- A polyaniline functionalized NiFeP nanosheet array-based electrochemical
immunosensor via Au/Cu2O nanocube as a signal amplifier for the detection
of SARS-CoV-2 nucleocapsid protein-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00616F, PaperLiwei Bai, Yufen Shi, Xue Zhang, Xiaowei Cao, Jianhua Jia, Huanhuan Shi, Wenbo Lu
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which emerged as a novel pathogen in 2019. The virus is responsible for...
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- In Vivo Measuring Autophagic Flux by Fluorescence Correlation Spectroscopy
-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00651D, PaperHaohan Song, Chaoqing Dong, Jicun Ren
Autophagy is a fundamental and phylogenetically conserved self-degradation process and plays very important role in the selective degradation of deleterious proteins, organelles, and other macromolecules. Although flow cytometry and fluorescence...
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- Towards therapeutic drug monitoring of antibiotic levels – analyzing the
pharmacokinetics of levofloxacin using DUV-resonance Raman spectroscopy-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00402C, PaperOpen Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Christian Domes, Juergen Popp, Stefan Hagel, Mathias W. Pletz, Torsten Frosch
Deep UV resonance Raman spectroscopy is a powerful technique for point-of-care monitoring of antibiotics level and paves the way for therapeutic drug monitoring in clinical practice.
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- Evaluating the biological effectiveness of boron neutron capture therapy
by using microfluidics-based pancreatic tumor spheroids-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D2AN01812H, PaperLin-Yen Yu, Chia-Hsien Hsu, Chia-Yang Li, Shiao-Ya Hong, Chaang-Ray Chen, Chi-Shuo Chen
Applications of tumor shperoids in microfluidic system for investigating the boron neutron capture therapy (BNCT).
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- Recent development of nanotechnology-empowered antigen assay methods for
the control of infectious diseases-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00328K, MinireviewHongzhen Peng, Hongxuan Fan, Eric Zhengliang He, Jiang Li
The global spread of air-borne diseases, such as Covid-19 caused by the new coronavirus (SARS-CoV-2), has significantly impacted public health and economic development worldwide. Accurate and rapid detection of pathogens...
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- A dual paper-based nucleic acid extraction method from blood in under ten
minutes for point-of-care diagnostics-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00296A, PaperOpen Access
  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Kenny Malpartida-Cardenas, Jake Baum, Aubrey Cunnington, Pantelis Georgiou, Jesus Rodriguez-Manzano
Dual, rapid, and simple paper-based nucleic acid extraction method from blood using filter paper for point-of-care diagnostics.
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- Label-free SERS ultrasensitive and universal detection of low back pain
fingerprint based on SERS substrate-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00097D, PaperCai Wang, Jixiang Chen, Jingguo Wu, Huiyu Wan, Qianwen Yue, Baoliang Sun, Ying Wang, Qiang Xiao, Jingyi Sun
A SERS biosensor, in conjunction with principal component analysis, was used to detect substance changes in the process of fasciitis. Changes in the concentrations of tryptophan, phenylalanine and glycogen were found to be the most obvious in the process of fasciitis.
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- A fluorescence-based sweat test sensor in a proof-of-concept clinical
study for COVID-19 screening diagnosis-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00429E, PaperIsaya Thaveesangsakulthai, Jinnawat Jongkhumkrong, Kaywalee Chatdarong, Pattama Torvorapanit, Wannee Sukbangnop, Thanasat Sooksimuang, Chadin Kulsing, Boosayarat Tomapatanaget
During the corona virus disease 2019 (COVID-19) pandemic period, rapid screening of covid-19 patients has been of great interest by developing a fluorescent sensor for complexation with nonanal, which is a marker for Covid-19 detection in sweat.
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- Reverse transcription-free digital-quantitative-PCR for microRNA analysis
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00351E, PaperHao T. Mai, Brice C. Vanness, Thomas H. Linz
Base-stacking digital-quantitative-PCR rapidly measures miRNA with single-molecule sensitivity in a microfluidic platform.
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- Advances in deoxyribonucleic acid extraction techniques and point-of-care
molecular diagnosis of foodborne pathogens-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00045A, Tutorial ReviewSivakumar Rajamanickam, Nae Yoon Lee
A conventional molecular assay-based point-of-care (POC) diagnostic test involves three major stages: deoxyribonucleic acid (DNA) extraction, amplification, and amplicon detection. Among these steps, DNA extraction is costly and time-consuming. Nevertheless,...
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- Magnetic Nanoprobes Enabled Lateral Flow Assays: Recent Advance
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00044C, Critical ReviewYing Zhao, Jingwei Sang, Yusheng Fu, Jiuchuan Guo, Jinhong Guo
In recent years, magnetic nanoparticle sensor technologies have attracted considerable interest in the point-of-care-testing (POCT) field, especially in Lateral Flow Immunoassays (LFIA). Although the visual signal of magnetic nanoparticles is...
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- Non-destructive distinction between geogenic and anthropogenic calcite by
Raman spectroscopy combined with machine learning workflow-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00441D, PaperOpen Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sara Calandra, Claudia Conti, Irene Centauro, Emma Cantisani
Here, we demonstrate, for the first time, the possibility of distinguishing between geogenic and anthropogenic calcite in a non-destructive and effective way, using high-resolution micro-Raman spectroscopy combined with machine learning workflow.
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- An adaptive three-dimensional hydrodynamic focused microfluidic impedance
flow cytometer-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00726J, PaperYang Zhou, Jiao Wang, TING LIU, Man Wu, Yuwei Lan, Chunping Jia, Jianlong Zhao
Microfluidic impedance cytometry is emerging as a label-free, low-cost and portable solution for cell analysis. Impedance-based cell or particle characterization is provided by microfluidic and electronic devices. We report the...
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- Comparison of the biological effects of gadodiamide (Omniscan) and
gadoteridol (ProHance) by means of multi-organ and plasma metabolomics-
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Abstract:Analyst, 2023, 148,2415-2424
DOI : 10.1039/D3AN00353A, PaperOpen Access
  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Francesca Romano, Enza Di Gregorio, Gelsomina Riccardi, Chiara Furlan, Nicola Cavallini, Francesco Savorani, Anna Di Porzio, Stefano De Tito, Antonio Randazzo, Eliana Gianolio, Nunzia Iaccarino
Multi-organ and plasma metabolomics reveals marked metabolic changes induced in brain, cerebellum and liver of mice treated with a linear gadolinium-based contrast agent.
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- Based on nucleophilic addition-elimination ratiometric fluorescent probe
for monitoring N2H4 in biological system and actual samples-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00755C, Paperyan shi, Fangjun Huo, Caixia Yin
Hydrazine (N2H4) is an important reagent in the field of fine chemical engineering. However, its accumulation in the environment and food chain could pose a great threat to food safety...
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- Charting and tracking the evolution of the SARS CoV-2 coronavirus variants
of concern with protein mass spectrometry-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00614J, PaperJoshua S. Hoyle, Christian Mann, Elma H. Akand, Kevin M. Downard
Evolution of the SARS-CoV2 coronavirus charted using a mass spectrometry based protein phylogenetic approach for over 3000 spike S-proteins. The tree correctly resolves all major variants with single point mutations identified and displayed on the tree.
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- CannibiSenS: An on-demand rapid screen for THC in human saliva
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00522D, PaperNathan Churcher, Vikram Dhamu, Shalini Prasad
Management of substances that possess a high potential for abuse require a comprehensive understanding of the temporal effects of a corresponding volume of intake. Cannabis is deemed as one of...
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- Screen printing and laser-induced flexible sensors for simultaneously
sensitive detection of uric acid, tyrosine, and ascorbic acid in sweat-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00591G, PaperShuwen Chen, Zhikang Cao, Kang Zhou, Shaoguang Li, Hui Li, Kaichen Xu, Haibin Tang, Heng Deng, Qitao Zhou, Jing Pan, Fan Xia
Wearable sweat sensor, which could continuously monitor biomolecules related to human physiological state, is emerging as a promising health surveillance equipment. However, the current related sensors cannot simultaneously achieve traditional...
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- Metabolomics of bacterial-fungal pairwise interactions reveal conserved
molecular mechanisms-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00408B, PaperGordon Luu, Jessica Little, Emily Pierce, Manon Morin, Celine Ertekin, Benjamin Wolfe, Oliver Baars, Rachel Dutton, Laura Margaret Sanchez
Bacterial-fungal interactions (BFIs) can shape the structure of microbial communities, but the small molecules mediating these BFIs are often understudied. We explored various optimization steps for our microbial culture and...
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- Diffraction-limited mid-infrared microspectroscopy to reveal a
micron-thick interfacial water layer signature-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00138E, PaperArmin Mozhdehei, Aneta Slodczyk, Eirik Almklov Magnussen, Achim Kohler, Christophe Sandt, Ferenc Borondics, Lionel Mercury
The potential of a supercontinuum laser besides synchrotron radiation to conduct high-resolution, diffraction limited FTIR measurements and to record a micron thick interfacial water layer near the solid surface.
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The content of this RSS Feed (c) The Royal Society of Chemistry
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- Enhancing the accuracy of Mid-Infrared Spectroscopy Liver Steatosis
quantification using Digital Image Analysis as Reference-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00324H, PaperIván Rienda, Isabel Ten-Doménech, Erika Moro, Marta Moreno-Torres, Judith Pérez-Rojas, Eugenia Pareja, Alvaro Perez-Rubio, Ramon Trullenque-Juan, Ramiro Jover, Bernhard Lendl, David Perez-Guaita, Julia Kuligowski, José V Castell, Guillermo Quintás
The assessment of liver steatosis is crucial in both hepatology and liver transplantation (LT) surgery. Steatosis can negatively impact the success of the LT. Steatosis is a factor for excluding...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Study on the relationship between crystallization characteristics of
quenched droplets and the effect of cell cryopreservation with Raman
spectroscopy-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00652B, PaperTaijie Zhan, Wenya Niu, Mengdong Cui, Hengxin Han, Hangyu Dang, Ning Guo, Ding Wang, Yan Hao, Chuanbao Zang, Yi Xu
The cryopreservation method of microdroplets has steadily become widely employed in the cryopreservation of microscale biological samples such as various types of cells due to its fast cooling rate, significant...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Fluorescent probe for lipid droplet polarity imaging with low viscosity
crosstalk-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00551H, PaperBo Lin, Zhenru Li, Qi Zan, Fan Li, Yang Shu, Jian-Hua Wang
Monitoring the variations of lipid droplets (LDs) polarity is of great significance for the investigation of LDs-related cellular metabolism and function. We hereby report a lipophilic fluorescent probe (BTHO) with...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Ultrasensitive detection of gastric cancer biomarkers via frequency
shift-based SERS microfluidic chip-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00535F, PaperYong Huang, Zhengqing Liu, Xiaogang Qin, Jia Liu, Yan Yang, Wei Wei
Highly sensitive protein biomarker detection is critical for the diagnosis of gastric cancer (GC) whereas accurate and sensitive detection of low-abundance proteins in early-stage GC is still a challenge. Herein,...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Mass producible, robust SERS substrates based on metal film on nanosphere
(MFON) on an adhesive substrate for detection of surface-adsorbed
molecules and their evaluation by helium ion microscopy-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00272A, PaperH. Takei, N. Saito, T. Okamoto, K. Watanabe, M. Westphal, R. Tomioka, A. Gölzhäuser
Robust adhesive tape embedded with silver nanoparticles is suitable for rapid detection of pesticides on agricultural produce.
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The content of this RSS Feed (c) The Royal Society of Chemistry
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- Leveraging mid-infrared spectroscopic imaging and deep learning for tissue
subtype classification in ovarian cancer-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D2AN01035F, PaperChalapathi Gajjela, Matthew Brun, Rupali Mankar, Sara Corvigno, Noah Kennedy, Yanping Zhong, Jinsong Liu, Anil Sood, David Mayerich, Sebastian Berisha, Rohith Reddy
Mid-infrared spectroscopic imaging (MIRSI) is an emerging class of label-free techniques being lever- aged for digital histopathology. Modern histopathologic identification of ovarian cancer involves tissue staining followed by morphological pattern...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Improving SERS biosensor for the analysis of ovarian cancer-derived small
extracellular vesicles-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00398A, PaperLong Ngo, Wei Zhang, Su Su Thae HNIT, Yuling Wang
Small extracellular vesicles (sEVs) are lipid bilayer vesicles that carry key molecules (e.g., proteins, DNAs, RNAs and lipids) for cell-to-cell communication, being regarded as promising biomarkers for cancer diagnosis. However,...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- An aptamer triple helix molecular switch for sensitive electrochemical
assay of lipocalin 1 biomarker via dual signal amplifications-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00524K, PaperJianglong Yao, Yujie Liu, Bingying Jiang, Ruo Yuan, Yun Xiang
Sensitively monitoring the concentration change of lipocalin 1 (LCN1) can provide data support for accurately diagnosing diabetic retinopathy and efficacy of treatment. Using a new aptamer triplex switch (ATS) probe...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Ultrasensitive detect of CA125 based on triple signal amplification
strategy with huge amount of loaded probes via exonuclease cyclic
cleavage, rolling cyclic amplification and strand self-growth-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00414G, PaperLi He, Ciping Chen, Yongge Liu, Hong Hai, Jianping Li
A novel electrochemiluminescence(ECL) aptamer biosensor with high sensitivity and selectivity for the detection of tumor biomarker carbohydrate antigen CA125 was constructed, and a strategy of triple amplification of signals was...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Principles and applications of green fluorescent protein-based biosensors:
A mini-review-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00320E, MinireviewFeng-xia Tian, Guangling Xu, Suo Zhou, Shuchang Chen, Dongmei He
Green Fluorescent Proteins (GFPs) are useful and essential biomolecules that have revolutionized biosensor research. Researchers have extensively utilized GFPs for designing fluorescence biosensors due to their intrinsic fluorescence, high stability,...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Alternative platform for COVID-19 diagnosis based on AuNP-modified
lab-on-paper-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00595J, PaperPornchanok Punnoy, Tatiya Siripongpreda, Trairak Pisitkun, Nadnudda Rodthongkum, Pranut Potiyaraj
COVID-19 has caused global health problems, and so rapid diagnosis is crucial to slow spread of the disease.
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The content of this RSS Feed (c) The Royal Society of Chemistry
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- Vibrational and Chiroptical Analysis of Blood Plasma for Hepatocellular
Carcinoma Diagnostics-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00164D, PaperOpen Access
  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ondrej Vrtelka, Kateřina Králová, Markéta Fousková, Lucie Habartova, Petr Hříbek, Petr Urbánek, Vladimir Setnicka
More than one fifth of the world’s population suffers from liver cirrhosis or other chronic liver diseases. Unfortunately, some of them will inevitably develop hepatocellular carcinoma (HCC), due to the...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Development of a modularized aptamer targeting the nuclear T-cell
suppressor PAC1-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00011G, PaperOpen Access
  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zixi Hu, Zhongyu Jiang, Zeliang Yang, Liang Liu, Zhenyu Zhu, Yan Jin, Yuxin Yin
The aptamer PA5c against PAC1 was selected by SELEX and the dual-module aptamer PAC1-AS could recognize nuclear PAC1 under physiological conditions to overcome the hurdle of oligonucleotide-based cellular delivery.
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- Hollow structure molecularly imprinted ratiometric fluorescence sensor for
selective and sensitive detection dopamine-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00528C, PaperXiqing Liu, Ying Fang, Deqiang Zhu, Jinyu Wang, Yu Wu, Tao wang, Yongqing Wang
Developing hollow-structure quantum dots carriers to increase quantum luminous efficiency was a creative idea for designing novel sensor. A ratiometric hollow CdTe@H-ZIF-8/CDs@MIPs sensor was developed for sensitive and selective detection...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Increasing peroxidase-like activity of MIL-100(Fe) nanozyme by
encapsulating Keggin-typed 12-phosphomolybdate and covering
three-dimensional graphene-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00038A, PaperYuhan Ji, Yupu Wei, Jinghui Shen, Jinlong Zhuo, Mingqi Xu, Yunliang Wang, Jing-Quan Sha
To improve the peroxides-like activities of metal-organic frameworks (MOFs) as nanozymes, ternary MIL-100(Fe)@PMo12@3DGO nanocomposite was designed and fabricated by encapsulating Keggin-typed H3PMo12O40 (PMo12) with the fast and reversible multi-electron redox...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Electrochemiluminescence imaging of a membrane carcinoembryonic antigen at
single tissue sections-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00187C, PaperJunwei Shi, Dongni Han, Zengyu Feng, Dechen Jiang, Depeng Jiang
Histopathological molecular testing of tissue sections is an essential step in tumor diagnosis; however, the commonly used immunohistochemical methods have problems such as low specificity and the subjective bias of the observer.
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- Digital multimeter-based portable photoelectrochemical immunoassay of
cardiac Troponin I with enzymatic biocatalytic precipitation-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00465A, PaperBizhen Huang, Jing Ran, Ruishen Li, Wei Zhuang, Jiabi Chen, Haixin Guo
Early diagnosis of acute myocardial infarction (AMI) can significantly reduce mortality, which can be achieved by highly sensitive detection of AMI-specific cardiac troponin I (cTnI) biomarkers. Herein a highly sensitive...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- “Lighting up” fluoride: cellular imaging and zebrafish model
interrogations using a simple ESIPT-based mycophenolic acid
precursor-based probe-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00646H, PaperNeha Jain, Prasad M. Sonawane, Haoyan Liu, Arkaprava Roychaudhury, Youngseob Lee, Jongkeol An, Donghyeon Kim, Dongwook Kim, Yunsu Kim, Yeu-Chun Kim, Kyung-Bin Cho, Hee-Sung Park, Cheol-Hee Kim, David G Churchill
The discovery and implementation of media that derive from bioinspired designs and bear optical readouts featuring large Stokes shifts are of continued interest to a wide varity of researchers and...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Saline Dry Fixation for Improved Cell Composition Analysis Using Raman
Spectroscopy-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D2AN01916G, PaperShreyas Rangan, Riley Wong, H. Georg Schulze, Martha Vardaki, Michael W Blades, Robin F. B. Turner, James M. Piret
Raman spectroscopy enables the label-free assessment of cellular composition. While live cell analysis is the most accurate approach for cellular Raman spectroscopy, the analysis of fixed cells has proved to...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Boosting the performance of iontophoretic biosensing system with graphene
aerogel and Prussian blue for highly sensitive and noninvasive glucose
monitoring-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00212H, PaperXiao Li, Tong Li, Baoyang Liu, Ning Hu, Tao Hu, Zhonghua Ni
Diabetes and impaired glucose regulation (IGR) threaten the lives and health of numerous patients. Interstitial fluid (ISF) glucose, displaying an excellent correlation to blood glucose, are highly desired to address...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Rapid determination of serum amyloid A with an upconversion luminescent
lateral flow immunochromatographic strip-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00482A, PaperXinwen Sun, Xiaoru Dai, Shisheng Ling, Wenkun Dong, Dong Chen, Mengting Li, Xvsheng Qiao, Zhiyu Wang, Xianping Fan, Guodong Qian
Household early diagnosis and real-time prognosis of Cardiovascular disease (CVD) at bedside are of significant importance. However, the real time detection of myocardial infarction still suffers from large-scale instruments and...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Target-activated T7 transcription circuit-mediated multiple cycling signal
amplification for monitoring of flap endonuclease 1 activity in cancer
cells-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00604B, PaperJin-zhi Zhang, Ning-ning Zhao, Zi-Yue Wang, Juan Hu, Chun-Yang Zhang
The structure-specific endonuclease flap endonuclease 1 (FEN1) is an essential functional protein in DNA replication and genome stability, and it has been identified as a promising biomarker and drug target...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- All-Electrical Antibiotic Susceptibility and Resistance Profiling of
Electrogenic Pseudomonas aeruginosa-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00401E, PaperZahra Rafiee, Seokheun Choi
There is a pressing need for evidence-based, non-surgical therapy guidance for biofilm-based infections. Conventional phenotypic or genotypic or emerging antibiotic susceptibility testing (AST) techniques cannot provide clinically relevant guidelines and...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- FRET probe for detecting two mutations in one EGFR mRNA
-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00554B, PaperOpen Access
  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Myat Thu, Kouta Yanai, Hajime Shigeto, Shohei Yamamura, Kazunori Watanabe, Takashi Ohtsuki
Technologies for visualizing and tracking RNA are essential in molecular biology, including in disease-related fields. In this study, we propose a novel probe set (DAt-probe and T-probe) that simultaneously detects...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- AN ENHANCED FLUORESCENT SENSOR SYSTEM BASED ON MOLECULARLY IMPRINTED
POLYMER CHIPS WITH SILVER NANOPARTICLES FOR HIGHLY-SENSITIVE ZEARALENONE
ANALYSIS-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D2AN01991D, PaperDaria Yarynka, Vladimir Chegel, Elena Piletska, Sergey Piletsky, Larysa Dubey, Igor Ya. Dubey, Roman Nikolaiev, Oleksandr Brovko , Tetyana Sergeyeva
A novel enhanced fluorescent sensor system for zearalenone (ZON) determination in flour samples is presented. The ZON-selective molecularly imprinted polymer (MIP) films were developed with a computational modelling method and...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- CuO nanorods decorated hemin-graphene with enhanced peroxidase-mimic
performance for colorimetric and electrochemical determination of
4-aminophenol with a smartphone-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00327B, PaperMiaomiao Li, Xiuying Peng, Zhiguang Liu, Yan Dai, Yujie Han, Lifang Fan, Yujing Guo
The detection of 4-aminophenol (4-AP) is of critical importance due to its high toxicity, and the development of accurate, sensitive, and portable methods for this purpose is essential. Here, a...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- From mouth to gut: microfluidic in vitro simulation of human
gastro-intestinal digestion and intestinal permeability-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D2AN02088B, PaperOpen Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Catarina Gonçalves, Miguel Xavier, Patrícia Rodrigues, Mafalda Dias Neto, Maria Inês Guedes , Victor Calero, Lorenzo Pastrana
Reproducible in vitro studies of bioaccessibility, intestinal absorption and bioavailability are key to the successful development of novel food ingredients or drugs aiming for oral administration. There is currently a...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Surfactant encapsulating N-doped carbon dots with enhanced optical
properties as selective sensor for Cr(VI) detection-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00517H, PaperQiumeng Chen, Nan Li, Yulu Tian, Qian Liu, Xue Zou, Meikun Fan, Zhengjun Gong
Detecting hexavalent chromium (Cr(VI)) is important for human health and environmental protection due to its high toxicity, carcinogenicity and persistence, but developing a sensor to selectively detect Cr(VI) remains challenges....
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Fe-N hollow mesoporous carbon spheres with high oxidase-like activity for
sensitive detection of alkaline phosphatase-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00475A, PaperChen Yanwen, Zhao Liu, Zhang BaoShuai, Guan YuQing, Cheng Yao, Xuan Xu
Due to the vital role of alkaline phosphatase (ALP) in clinical diagnoses and biomedical research, a sensitive and selective detection method for ALP activity is of considerable importance. Herein, a...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- A Critical Evaluation of Compressed Line-Scan Raman Imaging
-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00228D, PaperYajun Yu, Yichuan Dai, Xianli Wang, Kaiqin Chu, Zachary James Smith
The weak signal strength of Raman imaging leads to long imaging times. To increase the speed of Raman imaging, line scanning and compressed Raman imaging methods have been proposed. Here...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Ti3C2 MXene improved photoelectrochemical anode assembly of titanium
dioxide nanoarrays for microcystin-LR detection-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00506B, PaperYue Jia, Yu Du, Xiaoyue Zhang, Rui Xu, Xiang Ren, Dan Wu, Hongmin Ma, Qin Wei
MXene with metal-like properties in improvement of band gap and drive of photon-generated carrier transport have become one of the most promising co-catalysts. But their unavoidable two-dimension morphology limits applications...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Carbon Black as Colorimetric Labels of Immunochromatographic Test Strip
for Severe Fever with Thrombocytopenia Syndrome Virus Detection-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00515A, PaperHao Liu, Fang Ji, Shou-Nian Ding
To combat the ongoing threat posed by severe fever with thrombocytopenia syndrome virus (SFTSV), especially in underserved areas, there is an urgent need for an affordable and reliable point-of-care diagnostic...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- Trivalent Metal Ion Sensor: Enabled Bioimaging and Quantification of
Vaccine Deposited Al3+ at Lysosomes-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00562C, PaperKavyashree P., Ajmal Roshan Unniram Unniram Parambil, Akshay Silswal, Anup Pramanik, Apurba Lal Koner
The deposition of extracellular metallic debris occurs at well known 'recycle bin' of the cells named lysosomes. The pile-up of unwanted metal ions can cause dysfunction of hydrolyzing enzymes and...
The content of this RSS Feed (c) The Royal Society of Chemistry
-
- Sensing platform for nucleic acid detection based on 2-Aminopurine probe
sheared by trans-cleavage activity of CRISPR/Cas12a system-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00502J, PaperXiaolong Chen, Chaowang Huang, Qiao Hu, Jing Zhang, Dan Wang, Qianyi You, Mingdong Hu
Target double-stranded DNA (dsDNA) or single-stranded DNA (ssDNA) can activate the trans-cleavage activity of the CRISPR/Cas12a, cutting the surrounding non-target ssDNA arbitrarily. In typical CRISPR/Cas12a system, this non-target ssDNA with...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- SCX-tip aided LC-MS detection of active ricin via oligonucleotide
substrate for depurination kinetics-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00217A, PaperLei Guo, Zhifang Yang, Chenyu Wang, Lan Xiao, Chuang Wang, Li Tang, Jianwei Xie
The accurate, sensitive detection of active biotoxin proteins and thereafter their kinetics feature is vital for the upsurge of chemical attacks but is still limited. Here we report a liquid...
The content of this RSS Feed (c) The Royal Society of Chemistry
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- An integrated microfluidic chip for nucleic acid extraction and continued
cdPCR detection of pathogens-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00271C, PaperYaru Huang, Zehang Gao, Cong Ma, Yimeng Sun, Yuhang Huang, Chunping Jia, Jianlong Zhao, Shilun Feng
This paper introduces an enclosed microfluidic chip that integrates sample prepara-tion and chamber-based digital polymerase chain reaction (cdPCR). The sample preparation of the chip includes nucleic acid extraction and purification...
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- Green cellulose nanofiber-based printed electrode for practical highly
sensitive amoxicillin detection-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00453H, PaperShaimah Rinda Sari, Erika Shinchi, Kenji Shida, Yuly Kusumawati, Kartika A. Madurani, Fredy Kurniawan, Masato Tominaga
Simple electrochemical detection of the antibiotic amoxicillin (AMX) in water is crucial to mitigate health and environmental risks; however, the process requires single-use electrodes, which can increase the waste generated...
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- Chemiluminescence Resonance Energy Transfer-Based Multistage Nucleic Acid
Amplification Circuit for MiRNA Detection with Low Background-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00594A, PaperNana Kang, Benrui Weng, Sijia Liu, Huiran Yang, Siyuan Wang, Yaqi Liu, Jiabing Ran, Hanghang Liu, Zhangshuang Deng, Changying Yang, Huimin Wang, Fuan Wang
Chemiluminescence resonance energy transfer (CRET)-based assays have shown great potential in biosensing due to their negligible background autofluorescence, yet are still limited by their low sensitivity and short half-life luminescence....
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- Fabrication of molecularly-imprinted gold nanoparticles-embedded Fe-MOFs
for highly selective SERS detection of 17β-estradiol in milk-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00343D, PaperMengmeng Zhang, Zhouya Wu, Yunhan Yang, Jing Ye, Sheng Han, Yuanting Li
17β-Estradiol (17β-E2) could accumulate in human by milk thus cause diseases by interfering the function of endocrine system. But its detection at trace level in milk is still a challenge...
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- In Vivo Raman Spectroscopy in the Diagnostics of Colon Cancer
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00103B, PaperOpen Access
  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Markéta Fousková, Jan Vališ, Alla Synytsya, Lucie Habartova, Jaromír Petrtýl, Luboš Petruželka, Vladimir Setnicka
Early detection and accurate diagnosis of colorectal carcinoma are crucial for successful treatment, yet current methods can be invasive and even inaccurate in some cases. In this work, we present...
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- Understanding Radiation Response and Cell Cycle Variation in Brain Tumour
Cells using Raman Spectroscopy-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00121K, PaperOpen Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Iona Elizabeth Hill, Marie Boyd, Kirsty Milligan, Cerys Anne Jenkins, Annette Sorensen, Andrew Jirasek, Duncan Graham, Karen Faulds
Radiation therapy is currently utilised in the treatment of approximately 50% of cancer patients. A move towards patient tailored radiation therapy would help to improve the treatment outcome for patients...
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- An activatable nanoprobe based on nanocomposites of
visible-light-excitable europium(III) complex-anchored MnO2 nanosheets for
bimodal time-gated luminescence and magnetic resonance imaging of tumor
cells-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00405H, PaperBo Song, Huinan Yan, Jiao Jiang, Jing Yu, Shengjun Huang, Jingli Yuan
Bimodal imaging probes that combine magnetic resonance imaging (MRI) with photoluminescence imaging are quite appealing since they can supply both anatomical and molecular information to effectively ameliorate the accuracy of...
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- A protein aggregation platform that distinguishes oligomers from amyloid
fibrils-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00487B, PaperAmy Zhang, Diana Portugal Barron, Erica W Chen, Zhefeng Guo
Deposition of aggregated proteins is a pathological feature in many neurodegenerative disorders such as Alzheimer’s and Parkinson’s. In addition to insoluble amyloid fibrils, protein aggregation leads to the formation of...
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- An ultrasensitive electrochemical sensor for phospholipase C via signal
amplification based on breathing ATRP and its application-
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Abstract:Analyst, 2023, Advance Article
DOI : 10.1039/D3AN00234A, PaperXiwen Li, Peiran Meng, Mingyang Sun, Yue Chen, Zhiyi Song, Xinyao Wang, Na Li, Yue Sun
An ultrasensitive electrochemical sensor for phospholipase C was developed via signal amplification based on breathing ATRP.
To cite this article before page numbers are assigned, use the
DOI form of citation above.
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- Preparation and application of high-brightness red carbon quantum dots for
pH and oxidized L-glutathione dual response-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00383C, PaperYuwei Du, Lei Cao, Xinlu Li, Tongtong Zhu, Ruhong Yan, Wen-Fei Dong, Li Li
Carbon dots (CDs) with red fluorescence emission are highly desirable for use in bioimaging and trace substance detection, with potential applications in biotherapy, photothermal therapy, and tumor visualization. Most of...
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- Nitrogen-doped orange emitting carbon dots for β-carotene detection
and lysosomal imaging-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00319A, PaperXinlu Li, Tongtong Zhu, Yuwei Du, Haiyang Yan, Ruhong Yan, Wen-Fei Dong, Li Li
β-carotene is a natural antioxidant that has an indispensable effect on the growth and immunity of the human body. To detect β-carotene intracellular and in vitro, N-doped carbon quantum dots...
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- Near-infrared fluorescent probe for in-situ imaging SO2 Flux in
drug-induced liver injury-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00500C, Paperxingwei li, huming yan, Fangjun Huo, Yongbin Zhang, le zhang, haixian ren, Caixia Yin
Sulfur dioxide (SO2) has been widely applied as an important additive in various foods and drugs due to its antioxidant, antiseptic and bleaching properties. SO2 in living organisms plays a...
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- Carboxylated mesoporous carbon hollow spheres for efficient solid-phase
microextraction of aromatic amines-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00376K, PaperShixiang Chen, Zejun Yu, Wenmin Zhang, Hui Chen, Qingqing Ding, Jinhua Xu, Qidong Yu, Lan Zhang
An efficient and stable fiber coating is of great importance for solid-phase microextraction (SPME). In this study, carboxylated mesoporous carbon hollow spheres (MCHS-COOH) were developed as an efficient SPME coating...
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- Synthesis of trinuclear Zinc(II) cluster composed of [4.4.3.01,5]tridecane
cages: A rapid detection and degradation probe for chemical warfare agent
simulant diethyl cyanophosphonate in protein-rich food products-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00469D, PaperSahil Thakur, Jyoti Rohilla, Keshav Kumar, Harender Kumar, Raghubir Singh, Varinder Kaur, Ravneet Kaur, Raman Kamboj
Diethyl cyanophosphonate (DCNP), a simulant of Tabun, is a common pollutant in pharmaceutical waste and poses a high risk to living organisms. Herein, we demonstrate a compartmental ligand-derived trinuclear Zinc(II)...
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- CRISPR Cas12a-enabled biosensors coupled with commercial pregnancy test
strips for the visible point-of-care testing of SARS-CoV-2-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00284E, PaperPeijie Shen, Zhenjun Si, Di Huang, Zhipeng Xu, Ziyi Wang, Mengjun Fang, Zhinan Xu
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has promoted the development of nucleic acid diagnosis technology. Several platforms containing isothermal amplification methods have achieved sensitive and...
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- Identification of human milk oligosaccharide positional isomers by
combining IMS-CID-IMS and cryogenic IR spectroscopy-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00407D, PaperOpen Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ali H. Abikhodr, Ahmed Ben Faleh, Stephan Warnke, Vasyl Yatsyna, Thomas R Rizzo
High-resolution ion mobility spectrometry (IMS) coupled with cryogenic infrared spectroscopy has proven to be a powerful technique for the identification of oligosaccharides. However, the need for an extensive database, combined...
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- Tunable Graphene Oxide for Low-fouling Electrochemical Sensing of Uric
Acid in Human Serum-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00291H, PaperGang Li, Chunying Xu, Hui Xu, Liju Gan, Kai Sun, Baiqing Yuan
Although many works have been reported to improve the selectivity of uric acid (UA) to eliminate other electroactive interference species which coexist in biological fluids. Two main challenges associated with...
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- Inner filter effect-based near-infrared fluorescent probe for detection of
metronidazole on a smartphone-integrated analytical platform-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00039G, PaperShaojie Wang, Yongbo Wang, Yuanna Ning, Qiming Lliu
Antibiotic residues pose a serious threat to ecosystems and food safety. Developing convenient, visual, and on-site detection methods is therefore in high demand and has practical purpose. In this work,...
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- Construction of Rapid Electrochemical Biosensor Consisted of
nanozyme/aptamer conjugate for waterborne microcystin detection-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00391D, PaperPark Jeong Ah, Yein Kwon, Trung Hieu Vu, Xuan Ai Le, Hanbin Park, Hoseok Lee, Hye Kyu Choi, ChulHwan Park, Moon Il Kim, Taek Lee
Microcystin-LR (MC-LR) is a hepatotoxin generated by excessive proliferation of cyanobacteria, which is a threat to humans and wildlife. Therefore, the rapid detection of MC-LR is an important challenge. This...
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- Hapten Synthesis and a Colloidal Gold Immunochromatographic Strip Assay to
Detect Nitrofen and Bifenox in Fruits-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00358B, Paperpeng wang, Xin-Xin Xu, Lingling Guo, Liqiang Liu, Hua Kuang, jing xiao, Chuanlai Xu
In this study, we synthesized two haptens similar in structure to nitrofen, and screened out five monoclonal antibodies with the ability to recognize NIT and bifenox by competitive ELISA, with...
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- Self-constrained DNAzyme for aptamer-based and sensitive label-free
fluorescent assay of sarafloxacin via signal amplification cascades-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00476G, PaperQianying Wang, Junyi Zhang, Ruo Yuan, Yun Xiang
The convenient and sensitive assay of antibiotic residuals is important for monitoring food safety and human health. Here, with a new self-constrained metal ion-dependent DNAzyme and hybridization chain reaction (HCR)...
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- Wet nitrocellulose membrane for level 3 feature visualization of various
latent fingerprints and gender determination-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00511A, PaperLu Tian, Hongyu Chen, Xiangyu Sun, Lu Liu, Meiqin Zhang
A facile and high-resolution enhancement of latent fingerprints (LFPs) has been developed by using wet nitrocellulose (NC) membrane as a matrix under natural light. A clear fingerprint pattern could be...
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- Rapid exosome isolation and in situ multiplexed detection of exosomal
surface proteins and microRNAs on microfluidic platform-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00335C, PaperYulin Chen, Dan Gao, Qingyun Zhu, Bizhu Chu, Jie Peng, Jian Wang, Liping Liu, Yuyang Jiang
Exosomes are considered as promising biomarkers for early cancer diagnosis and prognosis. However, the majority of the researches focused on the single type of exosomal biomarkers cannot comprehensively reflect the...
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- Two-color Infrared Photothermal Microscopy
-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00042G, PaperCHANJONG PARK, Jong Min Lim, Seok-Cheol Hong, Minhaeng Cho
Infrared photothermal microscopy is an infrared (IR) imaging technique that enables non-invasive, non-destructive, and label-free investigations at the sub-micrometer scale. It has been applied in various research areas targeting pharmaceutical...
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- A novel electrochemical sensor based on gold nanobipyramids and
Poly-L-cysteine for sensitive determination of trilobatin-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00368J, PaperXue Mei, Wenchang Wang, Qingyi Li, Minxian Wu, Liyin Bu, Zhidong Chen
Trilobatin is a flavonoid that has wide application prospects for its pharmacological effects, such as anti-inflammation and anti-oxidation. In this work, a novel electrochemical sensor based on gold nanobipyramids (AuNBs)...
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- Selecting the appropriate indirect viability assay for 3D paper-based
cultures: A data-driven study-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00283G, PaperZachary Ryan Sitte, Tyler S. Larson, Julie C. McIntosh, Melanie Sinanian, Matthew Ryen Lockett
Cellular viability measurements quantify decreased proliferation or increased cytotoxicity caused by drug candidates or potential environmental toxins. Direct viability measures count each cell to provide an accurate readout. This approach...
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- An electrochemical chlorpromazine sensor based on gold-copper bimetal
synergetic molecularly imprinted interface on acupuncture needle electrode
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00373F, PaperJiandan Chen, Hongying Liu, Chenwei Wang, Kai Fan, Lihua Li, Yuqing Zhang, Fang Lu, Zheng-Zhi Yin, Zhong Lv
Chlorpromazine (CPZ) is a medicine for nervine disease. Measuring CPZ in vivo can assist doctors in evaluating patients’ blood drug concentration and monitoring drug metabolism. Therefore, an accurate in vivo...
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- Rapid and Highly Sensitive Immunosorbent Assay to Monitor Helicases
Unwinding Diverse Nucleic Acid Structures-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D2AN01989B, PaperJia-En Wang, Ying-Chen Zhou, Bi-Han Wu, Xiu-Cai Chen, Junqiu Zhai, Jia-Heng Tan, Zhi-Shu Huang, Shuo-Bin Chen
Helicases are crucial enzymes for DNA and RNA metabolism, which function by unwinding particular nucleic acid structures. However, most convenient and high-throughput helicase assays were limited on the typical duplex...
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- Detection of Saxitoxin by SERS aptamer sensor based on enzyme cycle
amplification technology-
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Abstract: Analyst, 2023, Accepted Manuscript
DOI : 10.1039/D3AN00330B, PaperBai xinna, Weifang Gong, Yaxin Guo, Di Zhu, Xue-Mei Li
Saxitoxin (STX) is a typical toxic guanidinium neurotoxin, one of the paralytic shellfish poisoning (PSP), which poses a serious threat to human health. In this paper, a simple and sensitive...
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