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  Subjects -> PSYCHOLOGY (Total: 983 journals)
Showing 1 - 174 of 174 Journals sorted alphabetically
Academic Psychiatry and Psychology Journal : APPJ     Open Access   (Followers: 24)
Acta Colombiana de Psicología     Open Access   (Followers: 5)
Acta Comportamentalia     Open Access   (Followers: 1)
Acta de Investigación Psicológica     Open Access   (Followers: 1)
Acta Psychologica     Hybrid Journal   (Followers: 22)
Activités     Open Access   (Followers: 1)
Actualidades en Psicologia     Open Access   (Followers: 2)
Adaptive Human Behavior and Physiology     Hybrid Journal   (Followers: 6)
Addictive Behaviors Reports     Open Access   (Followers: 8)
ADHD Attention Deficit and Hyperactivity Disorders     Hybrid Journal   (Followers: 17)
ADHD Report The     Full-text available via subscription   (Followers: 8)
Adolescent Research Review     Hybrid Journal   (Followers: 3)
Advanced Journal of Professional Practice     Open Access   (Followers: 2)
Advances in Experimental Social Psychology     Full-text available via subscription   (Followers: 38)
Advances in Mental Health     Hybrid Journal   (Followers: 82)
Advances in Methods and Practices in Psychological Science     Full-text available via subscription   (Followers: 19)
Advances in Neurodevelopmental Disorders     Hybrid Journal   (Followers: 3)
Advances in Physiotherapy     Hybrid Journal   (Followers: 65)
Advances in the Study of Behavior     Full-text available via subscription   (Followers: 31)
Affective Science     Hybrid Journal   (Followers: 3)
African Journal of Cross-Cultural Psychology and Sport Facilitation     Full-text available via subscription   (Followers: 5)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 365)
Aggressive Behavior     Hybrid Journal   (Followers: 16)
Aging Psychology     Open Access   (Followers: 2)
Aging, Neuropsychology, and Cognition     Hybrid Journal   (Followers: 42)
Ajayu Órgano de Difusión Científica del Departamento de Psicología UCBSP     Open Access  
Aletheia     Open Access   (Followers: 1)
American Behavioral Scientist     Hybrid Journal   (Followers: 21)
American Imago     Full-text available via subscription   (Followers: 4)
American Journal of Applied Psychology     Open Access   (Followers: 48)
American Journal of Community Psychology     Hybrid Journal   (Followers: 29)
American Journal of Health Behavior     Full-text available via subscription   (Followers: 23)
American Journal of Orthopsychiatry     Hybrid Journal   (Followers: 6)
American Journal of Psychoanalysis     Hybrid Journal   (Followers: 16)
American Journal of Psychology     Full-text available via subscription   (Followers: 44)
American Psychologist     Full-text available via subscription   (Followers: 191)
An-Nafs : Jurnal Fakultas Psikologi     Open Access  
Anales de Psicología / Annals of Psychology     Open Access   (Followers: 2)
Análise Psicológica     Open Access  
Analitika : Jurnal Magister Psikologi Uma     Open Access  
Analogías del Comportamiento     Open Access  
Analysis     Full-text available via subscription   (Followers: 2)
Annual Review of Clinical Psychology     Full-text available via subscription   (Followers: 84)
Annual Review of Organizational Psychology and Organizational Behavior     Full-text available via subscription   (Followers: 49)
Annual Review of Psychology     Full-text available via subscription   (Followers: 270)
Anuario de investigaciones (Facultad de Psicología. Universidad de Buenos Aires)     Open Access   (Followers: 1)
Anuario de Investigaciones de la Facultad de Psicología     Open Access  
Anuario de Psicología / The UB Journal of Psychology     Open Access   (Followers: 1)
Anuario de Psicología Jurídica     Open Access   (Followers: 1)
Anxiety, Stress & Coping: An International Journal     Hybrid Journal   (Followers: 19)
Applied Cognitive Psychology     Hybrid Journal   (Followers: 66)
Applied Neuropsychology : Adult     Hybrid Journal   (Followers: 47)
Applied Neuropsychology : Child     Hybrid Journal   (Followers: 27)
Applied Psycholinguistics     Hybrid Journal   (Followers: 26)
Applied Psychological Measurement     Hybrid Journal   (Followers: 18)
Applied Psychology     Hybrid Journal   (Followers: 156)
Applied Psychology: Health and Well-Being     Hybrid Journal   (Followers: 57)
Applied Psychophysiology and Biofeedback     Hybrid Journal   (Followers: 7)
Aprender     Open Access  
Archives of Clinical Neuropsychology     Hybrid Journal   (Followers: 33)
Archives of Depression and Anxiety     Open Access   (Followers: 1)
Archives of Scientific Psychology     Open Access   (Followers: 6)
Archives of Suicide Research     Hybrid Journal   (Followers: 11)
Arquivos Brasileiros de Psicologia     Open Access   (Followers: 1)
Art Therapy Online     Open Access   (Followers: 4)
Asia Pacific Journal of Counselling and Psychotherapy     Hybrid Journal   (Followers: 7)
Asia-Pacific Psychiatry     Hybrid Journal   (Followers: 5)
Asian American Journal of Psychology     Full-text available via subscription   (Followers: 7)
Asian Journal of Behavioural Studies     Open Access   (Followers: 3)
Asian Journal of Business Ethics     Hybrid Journal   (Followers: 9)
Assessment     Hybrid Journal   (Followers: 17)
Attachment: New Directions in Psychotherapy and Relational Psychoanalysis     Full-text available via subscription   (Followers: 13)
Attention, Perception & Psychophysics     Full-text available via subscription   (Followers: 15)
Augmented Human Research     Hybrid Journal   (Followers: 1)
Australian and Aotearoa New Zealand Psychodrama Association Journal     Full-text available via subscription   (Followers: 4)
Australian Journal of Psychology     Hybrid Journal   (Followers: 26)
Australian Psychologist     Hybrid Journal   (Followers: 14)
Autism Research     Hybrid Journal   (Followers: 45)
Autism Research and Treatment     Open Access   (Followers: 30)
Autism's Own     Open Access   (Followers: 11)
Avaliação Psicológica     Open Access  
Avances en Psicologia Latinoamericana     Open Access  
Aviation Psychology and Applied Human Factors     Hybrid Journal   (Followers: 27)
Balint Journal     Hybrid Journal   (Followers: 3)
Barbaroi     Open Access  
Basic and Applied Social Psychology     Hybrid Journal   (Followers: 39)
Behavior Analysis in Practice     Full-text available via subscription   (Followers: 16)
Behavior Analysis: Research and Practice     Full-text available via subscription   (Followers: 7)
Behavior Analyst     Hybrid Journal   (Followers: 6)
Behavior and Social Issues     Full-text available via subscription   (Followers: 1)
Behavior Modification     Hybrid Journal   (Followers: 13)
Behavior Research Methods     Hybrid Journal   (Followers: 26)
Behavior Therapy     Hybrid Journal   (Followers: 54)
Behavioral Development Bulletin     Full-text available via subscription   (Followers: 1)
Behavioral Disorders     Hybrid Journal   (Followers: 1)
Behavioral Interventions     Hybrid Journal   (Followers: 17)
Behavioral Neuroscience     Full-text available via subscription   (Followers: 63)
Behavioral Sciences & the Law     Hybrid Journal   (Followers: 28)
Behavioral Sleep Medicine     Hybrid Journal   (Followers: 12)
Behaviormetrika     Hybrid Journal  
Behaviour     Hybrid Journal   (Followers: 8)
Behaviour Change     Full-text available via subscription   (Followers: 11)
Behaviour Research and Therapy     Hybrid Journal   (Followers: 22)
Behavioural and Cognitive Psychotherapy     Hybrid Journal   (Followers: 129)
Behavioural Processes     Hybrid Journal   (Followers: 7)
Behavioural Public Policy     Hybrid Journal   (Followers: 3)
Behavioural Sciences Undergraduate Journal     Open Access   (Followers: 2)
Beyond Behavior     Hybrid Journal   (Followers: 2)
BioPsychoSocial Medicine     Open Access   (Followers: 8)
BMC Psychology     Open Access   (Followers: 20)
Body, Movement and Dance in Psychotherapy: An International Journal for Theory, Research and Practice     Hybrid Journal   (Followers: 13)
Boletim Academia Paulista de Psicologia     Open Access  
Boletim de Psicologia     Open Access  
Brain Informatics     Open Access   (Followers: 1)
Brain Science Advances     Open Access  
British Journal of Clinical Psychology     Full-text available via subscription   (Followers: 160)
British Journal of Developmental Psychology     Hybrid Journal   (Followers: 38)
British Journal of Educational Psychology     Hybrid Journal   (Followers: 37)
British Journal of Health Psychology     Hybrid Journal   (Followers: 49)
British Journal of Mathematical and Statistical Psychology     Full-text available via subscription   (Followers: 18)
British Journal of Psychology     Full-text available via subscription   (Followers: 75)
British Journal of Psychotherapy     Hybrid Journal   (Followers: 70)
British Journal of Social Psychology     Full-text available via subscription   (Followers: 45)
Buletin Psikologi     Open Access  
Cadernos de psicanálise (Rio de Janeiro)     Open Access   (Followers: 1)
Cadernos de Psicologia Social do Trabalho     Open Access   (Followers: 1)
Canadian Art Therapy Association     Hybrid Journal   (Followers: 1)
Canadian Journal of Art Therapy : Research, Practice, and Issues     Hybrid Journal   (Followers: 1)
Canadian Journal of Behavioural Science     Full-text available via subscription   (Followers: 7)
Canadian Journal of Experimental Psychology     Full-text available via subscription   (Followers: 17)
Canadian Psychology / Psychologie canadienne     Full-text available via subscription   (Followers: 11)
Case Studies in Sport and Exercise Psychology     Hybrid Journal   (Followers: 7)
Castalia : Revista de Psicología de la Academia     Open Access  
CASUS : Revista de Investigación y Casos en Salud     Open Access  
Cendekia : Jurnal Kependidikan dan Kemasyarakatan     Open Access  
CES Psicología     Open Access  
Child Development Perspectives     Hybrid Journal   (Followers: 37)
Child Development Research     Open Access   (Followers: 22)
Ciencia Cognitiva     Open Access   (Followers: 1)
Ciencia e Interculturalidad     Open Access   (Followers: 1)
Ciências & Cognição     Open Access  
Ciencias Psicológicas     Open Access  
Clínica y Salud     Open Access  
Clinical Medicine Insights : Psychiatry     Open Access   (Followers: 9)
Clinical Practice & Epidemiology in Mental Health     Open Access   (Followers: 3)
Clinical Practice in Pediatric Psychology     Full-text available via subscription   (Followers: 13)
Clinical Psychological Science     Hybrid Journal   (Followers: 16)
Clinical Psychologist     Hybrid Journal   (Followers: 22)
Clinical Psychology & Psychotherapy     Hybrid Journal   (Followers: 87)
Clinical Psychology and Special Education     Open Access   (Followers: 7)
Clinical Psychology Review     Hybrid Journal   (Followers: 55)
Clinical Psychology: Science and Practice     Hybrid Journal   (Followers: 29)
Clocks & Sleep     Open Access   (Followers: 1)
Coaching : Theorie & Praxis     Open Access   (Followers: 3)
Coaching Psykologi : The Danish Journal of Coaching Psychology     Open Access   (Followers: 3)
Cogent Psychology     Open Access  
Cógito     Open Access  
Cognition & Emotion     Hybrid Journal   (Followers: 43)
Cognitive Behaviour Therapist     Hybrid Journal   (Followers: 12)
Cognitive Behaviour Therapy     Hybrid Journal   (Followers: 20)
Cognitive Neuropsychology     Hybrid Journal   (Followers: 42)
Cognitive Psychology     Hybrid Journal   (Followers: 75)
Cognitive Research : Principles and Implications     Open Access   (Followers: 5)
Community Psychology in Global Perspective     Open Access   (Followers: 1)
Comprehensive Psychoneuroendocrinology     Open Access  
Comprehensive Results in Social Psychology     Hybrid Journal  
Consciousness and Cognition     Hybrid Journal   (Followers: 37)
Construção Psicopedagógica     Open Access  
Consulting Psychology Journal : Practice and Research     Full-text available via subscription   (Followers: 3)
Consumer Psychology Review     Hybrid Journal   (Followers: 3)
Contagion : Journal of Violence, Mimesis, and Culture     Full-text available via subscription   (Followers: 6)
Contemporary Educational Psychology     Hybrid Journal   (Followers: 29)
Contemporary Psychoanalysis     Hybrid Journal   (Followers: 1)
Contemporary School Psychology     Hybrid Journal   (Followers: 6)
Contextos Clínicos     Open Access  
Counseling et spiritualité / Counselling and Spirituality     Full-text available via subscription   (Followers: 1)
Counseling Outcome Research and Evaluation     Hybrid Journal   (Followers: 12)
Counseling Psychologist     Hybrid Journal   (Followers: 17)
Counseling Psychology and Psychotherapy     Open Access   (Followers: 19)
Counselling and Psychotherapy Research : Linking research with practice     Hybrid Journal   (Followers: 23)
Counselling and Values     Hybrid Journal   (Followers: 5)
Counselling Psychology Quarterly     Hybrid Journal   (Followers: 13)
Couple and Family Psychoanalysis     Full-text available via subscription   (Followers: 2)
Couple and Family Psychology : Research and Practice     Full-text available via subscription   (Followers: 9)
Creativity Research Journal     Hybrid Journal   (Followers: 24)
Creativity. Theories ? Research ? Applications     Open Access   (Followers: 6)
Crime Psychology Review     Hybrid Journal   (Followers: 2)
Criminal Justice Ethics     Hybrid Journal   (Followers: 10)
Cuadernos de Marte     Open Access  
Cuadernos de Neuropsicología     Open Access   (Followers: 1)
Cuadernos de Psicologia del Deporte     Open Access  
Cuadernos Hispanoamericanos de Psicología     Open Access  
cultura & psyché : Journal of Cultural Psychology     Hybrid Journal   (Followers: 1)
Cultural Diversity and Ethnic Minority Psychology     Full-text available via subscription   (Followers: 18)
Cultural-Historical Psychology     Open Access   (Followers: 4)
Culture - Society - Education     Open Access   (Followers: 2)
Culture and Brain     Hybrid Journal   (Followers: 6)
Current Addiction Reports     Hybrid Journal   (Followers: 13)
Current Behavioral Neuroscience Reports     Hybrid Journal   (Followers: 4)
Current Directions In Psychological Science     Hybrid Journal   (Followers: 73)

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Similar Journals
Journal Cover
Neurology, Neuropsychiatry, Psychosomatics
Journal Prestige (SJR): 0.124
Number of Followers: 6  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2074-2711 - ISSN (Online) 2310-1342
Published by IMA-PRESS, LLC Homepage  [1 journal]
  • Social adaptation level and its relationship with the main clinico-dynamic
           and psychological characteristics in the comorbidity of affective
           disorders and alcohol dependence

    • Authors: Roshchina O.V; Simutkin G.G, Bokhan N.A, Surovtseva A.K.
      Abstract: Alcohol dependence (AD) and mood disorders are not only a serious medical and socio-economic problem for modern society, but also the cause of social adaptation disorders that form even in the early stages of each of these disorders, as well as in case of their comorbidity.Objective: to determine the relationship between the level of subjective assessment of social adaptation and the main clinical, dynamic and psychological characteristics in patients with affective disorders (AFD) with comorbid AD.Patients and methods. The study included 126 patients treated for AFD in the departments of affective or addictive conditions of the clinic of the Research Institute of Mental Health of the Tomsk National Research Medical Center (F31 – F34.1 according to ICD-10; n=83) or AFD comorbid with AD (F10. 2; n=43). The study used clinical-dynamic, psychometric, pathopsychological and statistical methods.Results and discussion. Patients with AFD without comorbidity at admission were characterized by a greater severity of subjective impairment of social adaptation and anhedonia; hypochondriacal, depressive, psychasthenic and schizoid traits predominated in the structure of their personality. At the same time, the condition of patients with AFD and AD comorbidity was objectively assessed as more severe. An inverse correlation was found between the level of subjective assessment of social adaptation and anhedonia in the group of patients with «pure» AFD, and in the group with AFD and AD comorbidity, with the severity of depressive symptoms (due to typical depressive symptoms), as well as with depressive and anxious personality traits of patients.Conclusion. Self-assessment of social adaptation of patients with “pure” AFD depends on the intensity of anhedonia manifestations, and in patients with AFD and AD comorbidity, on depressive symptoms (due to typical depressive symptoms) and on the severity of such psychological characteristics as depression and psychasthenia.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • The efficacy of ipidacrine in patients with diabetic polyneuropathy

    • Authors: Kamchatnov P.R; Barantsevich E.R, Chugunov A.V, Kabanov A.A, Abusueva B.A.
      Abstract: Peripheral nervous system involvement in patients with type 2 diabetes mellitus is a severe complication associated with a decrease in the quality of life, the development of disability and lethal outcomes. The most negative in terms of prognosis is autonomic diabetic polyneuropathy (DPN).Objective: to study the effectiveness of the drug ipidacrine (Ipigrix) in patients with DPN.Patients and methods. 49 patients with DPN were observed, they were divided into three groups. Patients of the 1st group (n=16) received ipidacrine 20 mg orally 3 times a day for 60 days, patients of the 2nd group (n=17) received ipidacrine 15 mg 1 time per day intramuscularly for 15 days, then – 20 mg 3 times a day orally up to 2 months; patients of the 3rd group (n=16) received only basic therapy. The clinical condition, severity of pain syndrome according to the Neurological Symptoms Score (NSS), vegetative tests, and treatment tolerance were assessed.Results and discussion. The therapy was effective in terms of reducing the severity of neuropathic pain syndrome, as well as normalizing the results of vegetative tests. In patients of the 1st group, the total scores on the NSS scale decreased by 37% (p<0.05) by the 60th day of treatment. In patients of the 2nd group, the total scores on the NSS scale decreased by 22% by the 30th day (p<0.05) and by 35% (p<0.05) by the 60th day of treatment. A pronounced positive effect in terms of vegetative tests was noted on the 60th day of treatment in the 1st and 2nd groups of patients. No adverse events were observed during the treatment period in any of patients of the 1st and the 2nd groups. In the comparison group, there were no significant changes in scores on the NSS scale and indicators of vegetative samples.Conclusion. The effectiveness of the drug ipidacrine (Ipigrix) in patients with pain and vegetative manifestations of DPN was noted.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • The prevalence of cognitive impairment and their association with
           socioeconomic, demographic and anthropometric factors and geriatric
           syndromes in people over 65 years of age: data from the Russian
           epidemiological study EVKALIPT

    • Authors: Mkhitaryan E.A; Vorobieva N.M, Tkacheva O.N, Kotovskaya Y.V, Koberskaya N.N, Selezneva E.V, Ovcharova L.N.
      Abstract: Cognitive dysfunction is one of the most common disorders in the elderly and senile age. There are currently 57 million people with dementia worldwide.Objective: to assess cognitive functions, to understand the prevalence of cognitive impairment (CI) and to analyze their associations with socioeconomic, demographic and anthropometric factors and geriatric syndromes in people aged ≥65 years.Patients and methods. Subjects living in 11 regions of the Russian Federation took part in the EVKALIPT epidemiological study. The inclusion criterion was age ≥65 years. Participants were divided into three age groups (65–74 years, 75–84 years, and ≥85 years) according to the protocol. All patients underwent a comprehensive geriatric assessment, comprising a specially designed questionnaire and physical examination. Cognitive functions were assessed using the mini-Cog test. The study included 3545 patients (of which 30% were males) aged 65 to 107 years.Results and discussion. According to the data obtained in our study, CI was detected in 60.8% of the subjects, and severe disorders – in 19.9% (0 or 1 point according to the mini-Cog). Patients with CI had a lower socioeconomic status. One-way regression analysis showed that the risk of CI increased by 10% with increasing age for every 1 year but did not depend on the sex of the subjects. Associated with increased CI risk also were: living alone (by 28%), living in a nursing home (by 90%), widowhood (by 2.2 times) or absence of a partner (by 2.2 times), underweight (by 2.9 times) and normal body weight (by 1.6 times), disability (by 54%), primary (by 4.8 times) and secondary (by 75%) education, bad economic conditions (by 95%). On the contrary, the presence of overweight and obesity reduced the risk of CI by 14 and 24% respectively, living in a family – by 24%, having a spouse – by 55%, divorce – by 29%, having a job – by 73%, higher education and a scientific degree – by 55 and 59%, medium and good economic conditions – by 38 and 52%, respectively. In patients with CI, the incidence of all geriatric syndromes was higher.Conclusion. The frequency of CI among elderly patients was higher compared with data from other studies. The EVKALIPT study was the first to obtain national data on the prevalence and characteristics of CI in persons aged ≥65 years in the general population.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • Neuropsychiatric disorders correction in Alzheimer's disease

    • Authors: Koberskaya N.N.
      Abstract: Behavioral and neuropsychiatric symptoms occur in 80% of patients with Alzheimer's disease (AD) and represent one of the most common reasons for early hospitalization and increased treatment costs. It is believed that the development of mental disorders (MD) is a marker of a number of additional adverse outcomes in patients with AD. The disease is accompanied by the development of other behavioral disorders, the most unpleasant of which are agitation (excitation) and aggression. The article discusses the causes and factors that can provoke the development of MD in AD. Traditionally used pharmacotherapeutic methods for the treatment of MD in AD in this age group have limited efficacy and are characterized by high toxicity. Antipsychotics are often associated with serious side effects and increased mortality in patients with dementia. A clinical case of AD with the development of neuropsychiatric disorders is presented. We discuss the issue of nonpharmacological strategies that have been shown to be more effective than pharmacological treatment and have fewer side effects than antipsychotic pharmacotherapy. On the example of the given clinical case, modern approaches to the correction of such complications and the management of this group of patients are shown. It seems appropriate to use memantine (akatinol memantine) in patients with neuropsychiatric symptoms of AD. In clinical studies, memantine has shown a positive effect in terms of reducing the rate of deterioration of general, cognitive, functional and behavioral parameters compared with treatment with antipsychotics. The drug is characterized by a minimum number of side effects and a limited range of contraindications.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • Hemimasticatory spasm: possibilities of treatment with injections of
           botulinum neuroprotein type A (case report)

    • Authors: Valieva L.U; Pankratov A.S, Orlova O.R.
      Abstract: Objective: to study the possibilities and effectiveness of treatment of patients with hemimasticatory spasm (HMS) with injections of botulinum neuroprotein type A (BNPA). The authors present a clinical case of long-term HMS: a 50-year-old patient, who suffered from the age of 20 from frequent involuntary muscle contractions that occurred in the temporal and masticatory muscles of the left half of the face. The patient was observed by neurologists for a long time, while the prescribed therapy did not have a satisfactory result. In the process of a comprehensive examination of the patient, in addition to intense involuntary contraction and pronounced hypertrophy of the affected muscles, secondary compensatory changes in other masticatory muscles were revealed, both on the side of the lesion and on the opposite side. BNPA treatment led to a robust improvement in the patient's condition.For patients with a long course of HMS and hypertrophy of the muscles involved in the pathological process, the use of bilateral injections of BNPA is the method of choice, since it not only effectively reduces the number of episodes, but also restores muscle balance, and also restores the motor function of the entire masticatory muscle group.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • Approaches to psychotherapy for chronic musculoskeletal pain

    • Authors: Petelin D.S; Istomina N.S, Tsapko D.S, Magomedov A.A, Bezrukov V.E, Kochergina M.S, Gamirova A.N, Volel B.A.
      Abstract: The management of patients with chronic musculoskeletal pain is an important biomedical problem due to the prevalence of this pathology and its resistance to therapeutic interventions. Psychosocial factors play a significant role in the formation and maintenance of chronic pain. In this regard, psychotherapeutic assistance is very important in the management of patients with chronic pain within the framework of multidisciplinary treatment. This review discusses the main psychotherapeutic approaches that have been used for chronic musculoskeletal pain: cognitive behavioral therapy, mindfulness therapy, psychoanalysis, hypnosis. General information about the essence of the discussed methods and the evidence base for their use in chronic pain are presented. A significant effectiveness of cognitive-behavioral therapy and techniques based on mindfulness therapy has been demonstrated.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • Combined therapy for Alzheimer's disease

    • Authors: Zakharov V.V; Lokshina A.V, Vakhnina N.V.
      Abstract: Alzheimer's disease (AD) is the most common cause of cognitive impairment and dementia. A non-systematic review of literature is presented, which discusses the clinical features and current criteria for diagnosis of this disease. The review presents classifications of cognitive impairments, including severity, as well as diagnostic criteria for various stages of dementia. The main approaches to the management of patients with dementia in AD as the disease progresses are highlighted. Modern publications dedicated to the problem of combined therapy of dementia in AD with donepezil and memantine are considered. The fixed combination of these drugs in a single tablet once daily regimen has been shown to provide significant benefits over acetylcholinesterase inhibitor monotherapy, especially in patients with dysphagia, poor adherence to treatment and limited interaction with caregivers.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • Possibilities of antiplatelet therapy in non-cardioembolic ischemic stroke

    • Authors: Maksimova M.Y; Airapetova A.S.
      Abstract: Most patients survive their first non-cardioembolic ischemic stroke (IS), but a significant proportion of them experience a second stroke within the first year. The main directions for the prevention of recurrent IS are antihypertensive and lipid-lowering therapy, control of glucose levels in patients with diabetes mellitus, and smoking cessation. Clinical guidelines recommend the use of antiplatelet therapy in patients with noncardioembolic IS or transient ischemic attack (TIA). The administration of antiplatelet agents to patients who have had a TIA or stroke reduces their risk of recurrent stroke by 23% and the overall risk of vascular events (myocardial infarction, stroke, and death from cardiovascular disease) by 17% (Antithrombotic Trialists' Collaboration, 2009). Acetylsalicylic acid (ASA), the combined use of clopidogrel and ASA, and the combination of ASA with sustained release dipyridamole have been shown to be effective for secondary prevention of non-cardioembolic IS. Intensive antiplatelet therapy reduces the risk of recurrent stroke, but increases the frequency of bleeding.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • Cognitive and emotional disorders in patients with chronic heart failure:
           prospects for detection and correction

    • Authors: Shishkova V.N.
      Abstract: The article presents current data on the prevalence of anxiety, depressive disorders and cognitive impairment in patients with chronic heart failure (CHF). Data on the main pathogenetic mechanisms of the relationship in the development of emotional and cognitive impairments in patients with CHF are summarized. Recommendations for screening for cognitive and emotional disorders in this patient are given. The prospects for the correction of these disorders in patients with CHF are discussed, including within the framework of interdisciplinary cooperation.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • Anticoagulant therapy as a part of secondary stroke prevention in patients
           with atrial fibrillation

    • Authors: Ostroumova O.D; Ostroumova T.M.
      Abstract: Atrial fibrillation (AF) is the main cause of cardioembolic ischemic stroke (IS), it occurs in 25–35% of patients with IS, and its presence increases the risk of recurrent stroke compared with patients with sinus rhythm. The main method of preventing recurrent IS in AF is the administration of oral anticoagulants (OACs); in non-valvular AF, direct OACs (DOACs) have an advantage. Meta-analysis of randomized clinical trials showed a 19% greater reduction of stroke and systemic embolism risk in the DOACs group compared to warfarin (p<0.0001), including a 51% greater hemorrhagic stroke (HS) risk reduction (p<0.0001). In an additional sub-analysis of the ARISTOTLE trial, patients with AF and a history of stroke/transient ischemic attack showed a significant reduction in the risk of all types of strokes and HS. Although no randomized trial explored the direct comparisons of drugs from the DOACs group, data from observational studies indicate the potential advantage of apixaban in terms of reducing the risk of IS. Russian 2020 clinical guidelines for AF treatment suggest that the resumption/initiation (1–3–12 days) of anticoagulant therapy after an IS should be determined by the decision of a multidis ciplinary team (neurologist, cardiologist, neuroimaging specialist) based on recurrent IS and bleeding risk assessment. According to the 2020 guidelines of the Ministry of Health, the resumption of OACs therapy after an intracranial hemorrhage in patients with AF may be recommended 4–8 weeks after the event, and the decision to reinitiate therapy, as well as after IS, should be made by a multidisciplinary team.
      PubDate: Mon, 20 Jun 2022 00:00:00 +030
       
  • Acute and long-term neurological disorders in patients with coronavirus
           infection

    • Authors: Parfenov V.A; Kulesh A.A.
      Abstract: Currently, patients who attribute their complaints and disorders to the past COVID-19 are turning to a neurologist for a consultation. One should consider dangerous complications of COVID-19 such as stroke, including cerebral venous thrombosis, autoimmune encephalitis and myelitis, posterior reversible encephalopathy syndrome, Guillain–Barre’ syndrome. Disorders of consciousness, disorders of smell and taste, headache and dizziness are significantly more often present in the acute period of COVID-19. Long-term persistence of complaints and disorders after COVID-19 is regarded as post-COVID syndrome (PCS). Neurological complaints and disorders in a patient who has had COVID-19 are often caused by the development or exacerbation of a comorbid disease, including primary headache, musculoskeletal pain in the neck and back, various vestibular disorders, Alzheimer's disease, anxiety and depressive disorders. Unfortunately, in real clinical practice, these diseases are often not diagnosed, patients are observed with a diagnosis of PCS, and it is not taken into account that the basis for diagnosing PCS is the exclusion of other diseases that can explain complaints and disorders in a patient who has suffered from COVID-19.
      PubDate: Sun, 19 Jun 2022 00:00:00 +030
       
  • Anamnestic, clinical and laboratory features of the acute period of
           ischemic stroke in young patients

    • Authors: Gusev V.V; Kovtun O.P, Lvova O.A, Partylova E.A, Sergeev A.P, Sergeeva M.V, Yanchuk I.T, Dobrazova D.A, Suvorkov P.A, Shamalov N.A.
      Abstract: Objective: to study the anamnestic, clinical and laboratory features of the acute period of ischemic stroke (IS) and to determine the risk factors for its development in young patients.Patients and methods. Clinical and statistical processing of data of 256 patients aged 18 to 44 years included, who had IS, confirmed by computed and/or magnetic resonance imaging of the brain in the acute period, was carried out. Furthermore, in 154 patients and in 117 healthy participants, who made up the control group, eight polymorphisms of the thrombophilic spectrum genes were determined – FGB: -455G>A, F2: 20210G>A, F5: 1691G>A, F7: 10976G>A, F13: 103 G>T, ITGA2: 807C>T, ITGB3: 1565 T>C, PAI-1: -675 5G>4G.Results and discussion. 154 (60.15%) patients demonstrated good recovery (achievement of a level of ≤2 points on the Rankin scale by the patient). None of the patients died during their hospitalization. In the evaluated group of patients, we identified allelic variants of the thrombophilic spectrum genes and gene-gene combinations, the carriage of which increased the likelihood of IS development at the young age by 1.74 and 2.19 times, respectively. Taking into consideration additional examination methods, the pathogenetic variant of IS according to the TOAST classification was verified in 226 (88%) patients.Conclusion. In IS at a young age a detailed assessment of risk factors is required, including an analysis of carrier variants and combinations of procoagulant and prothrombotic spectrum gene polymorphisms.
      PubDate: Sun, 19 Jun 2022 00:00:00 +030
       
  • The impact of non-motor disorders on the quality of life of patients with
           cervical muscular dystonia

    • Authors: Nodel M.R; Salouhina N.I, Tolmacheva V.A.
      Abstract: Cervical dystonia (CD) has a wide range of non-motor (neuropsychiatric, sensory, dyssomnic) disorders. Relationships between dystonia, nonmotor manifestations of the disease and patients quality of life (QoL) require clarification.Objective: to clarify the impact of dystonia, sensory, affective, behavioral disorders, quality of sleep and wakefulness on the quality of life of patients with CD.Patients and methods. We examined 61 patients with CD (mean age – 48.03±11.49 years, mean duration of CD – 4.89±4.05 years). We used Toronto Western Hospital Spasmodic Torticollis Rating Scale (TWSTRS), Cervical Dystonia Quality of Life Questionnaire (CDQ-24, with five subscales: «stigma», «emotional wellbeing», «pain», «activities of daily living», «social/family life»), Spielberger–Khanin Inventory (STAI),Beck Depression Inventory (BDI), Barratt Behavioral Impulsivity (BIS-11), Yale–Brown Obsessive Compulsive Scale (Y-BOCS), Montreal Cognitive Assessment Scale (MoCA), Stroop Test (VST), 12 Word Memory Test, Pittsburgh Sleep Quality Assessment Scale (PSQI), Epworth Sleepiness Scale (ESS).Results and discussion. There was a deterioration in all characteristics of QoL in patients with CD, largely in emotional well-being, stigmatization, pain syndrome (50% change from the maximum CDQ-24 score). A statistically significant moderate correlation was established between the total assessment of QoL and the severity of dystonia (r=0.35; p<0.01), a statistically significant strong correlation between the total assessment of QoL and depression index (r=0.73; p<0.001 ), moderate strength correlation – with indicators of anxiety (r=0.65; p<0.01), obsessivecompulsive disorders (r=0.61; p<0.01), sleep quality (r=0.52; p<0.001), impulsiveness in behavior (r=0.31; p<0.01), weak relationship with the assessment of executive cognitive functions (according to the Stroop test interference index; r=0.24; p<0.01). A statistically significant moderate correlation was found between the assessments of activity in everyday, social/family life and impulsiveness in behavior (r=0.33; p<0.001); between stigma, emotional well-being and an indicator of executive cognitive functions (r=0.3; p<0.05). There were no statistically significant relationships between indicators of affective, cognitive functions, behavioral disorders and the severity of dystonia. There was a moderate correlation between pain score and dystonia severity (r=0.35; p<0.01).Conclusion. The decrease in QoL in patients with CD is largely due to affective, sensory, and behavioral disorders. Diagnosis and appropriate therapy of the non-motor aspects of the disease are required for adequately improvement of QoL of patients.
      PubDate: Sun, 19 Jun 2022 00:00:00 +030
       
  • Comorbidities and therapy for chronic non-specific low back pain and
           fibromyalgia

    • Authors: Nasonova T.I; Parfenova E.V.
      Abstract: Fibromyalgia (FM) often occurs under the mask of non-specific low back pain (NLBP).Objective: to compare the combined disorders and treatment efficacy in FM and chronic NLBP (chNLBP).Patients and methods. We examined 33 patients with chNLBP (27 women and 6 men, mean age 51.5±16.7 years) and 53 patients with FM (47 women and 6 men, mean age 46.8±14.6 years). Pain intensity was assessed using a numerical rating scale (NRS), using the Hospital Anxiety and Depression Scale (HADS), the Screening for Somatoform Symptoms-2 (SOMS-2), the Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), updated Fibromyalgia Impact Questionnaire (FIQR; disability in patients with FM), Oswestry Index (IO; disability in patients with chNLBP). Comprehensive treatment of patients included educational conversations, cognitive behavioral therapy, kinesitherapy, among drugs antidepressants, and in patients with FM anticonvulsants.Results and discussion. Previously, the diagnosis of FM was established only in 15% of patients, the diagnosis of chNLBP – in 82% of patients. The intensity of pain in FM was 7.1±1.9 points according to the NRS and was higher than in chNLBP (5.6±2.4 points; p=0.002). In the group of patients with FM compared to patients with chNLBP, significantly higher values of anxiety according to HADS (10.9±4.5 and 6.9±4.0 points; p<0.001), sleepiness according to ESS (8.2±4.6 and 6.2±4.6 points; p=0.014), somatization according to SOMS-2 (28.0 and 20.0 points; p<0.001) were detected. Possible anatomical causes of pain have been identified in all patients with chNLBP and only in 13% of patients with FM. 6 months after thestart of treatment in the FM group, pain intensity significantly (p<0.001) decreased to 3.7±2.6 points according to the NRS, anxiety to 6.7±3.5 points according to HADS, depression to 4.7±2 .6 points according to HADS, disability from 54.9±18.4 to 34.0±20.2 points according to FIQR; in chNLBP group pain intensity significantly (p<0.05) decreased to 2.6±2.1 points according to the NRS, anxiety decreased to 4.2±2.5 points according to HADS, depression to 6.5±3.3 points according to HADS, disability from 37.8±17.4 to 14.5±14.2 points according to IO.Conclusion. FM is less frequently diagnosed in comparison with chNLBP, accompanied by a higher pain intensity, anxiety, sleepiness and somatization. Complex therapy leads to a stable positive effect both in chNLBP and in FM.
      PubDate: Sun, 19 Jun 2022 00:00:00 +030
       
 
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