Subjects -> BIOLOGY (Total: 3134 journals)
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BIOLOGY (1491 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 1720 Journals sorted alphabetically
AAPS Journal     Hybrid Journal   (Followers: 30)
Abasyn Journal of Life Sciences     Open Access   (Followers: 3)
ACS Pharmacology & Translational Science     Hybrid Journal   (Followers: 5)
ACS Synthetic Biology     Hybrid Journal   (Followers: 38)
Acta Biologica Hungarica     Full-text available via subscription   (Followers: 5)
Acta Biologica Marisiensis     Open Access   (Followers: 3)
Acta Biologica Sibirica     Open Access   (Followers: 2)
Acta Biologica Turcica     Open Access   (Followers: 1)
Acta Biomaterialia     Hybrid Journal   (Followers: 31)
Acta Biotheoretica     Hybrid Journal   (Followers: 3)
Acta Chiropterologica     Full-text available via subscription   (Followers: 5)
acta ethologica     Hybrid Journal   (Followers: 7)
Acta Fytotechnica et Zootechnica     Open Access   (Followers: 3)
Acta Ichthyologica et Piscatoria     Open Access   (Followers: 5)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Musei Silesiae, Scientiae Naturales     Open Access  
Acta Neurobiologiae Experimentalis     Open Access  
Acta Scientiae Biological Research     Open Access   (Followers: 1)
Acta Scientiarum. Biological Sciences     Open Access   (Followers: 2)
Acta Scientifica Naturalis     Open Access   (Followers: 4)
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis     Open Access   (Followers: 2)
Acta Universitatis Lodziensis : Folia Biologica et Oecologica     Open Access  
Actualidades Biológicas     Open Access   (Followers: 1)
Advanced Biology     Hybrid Journal   (Followers: 1)
Advanced Health Care Technologies     Open Access   (Followers: 12)
Advanced Journal of Graduate Research     Open Access   (Followers: 1)
Advanced Membranes     Open Access   (Followers: 5)
Advanced Quantum Technologies     Hybrid Journal   (Followers: 3)
Advances in Bioinformatics     Open Access   (Followers: 22)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4)
Advances in Biology     Open Access   (Followers: 12)
Advances in Biomarker Sciences and Technology     Open Access   (Followers: 3)
Advances in Biosensors and Bioelectronics     Open Access   (Followers: 6)
Advances in Cell Biology/ Medical Journal of Cell Biology     Open Access   (Followers: 26)
Advances in Ecological Research     Full-text available via subscription   (Followers: 45)
Advances in Environmental Sciences - International Journal of the Bioflux Society     Open Access   (Followers: 17)
Advances in Enzyme Research     Open Access   (Followers: 10)
Advances in High Energy Physics     Open Access   (Followers: 26)
Advances in Human Biology     Open Access   (Followers: 8)
Advances in Life Science and Technology     Open Access   (Followers: 12)
Advances in Life Sciences     Open Access   (Followers: 5)
Advances in Marine Biology     Full-text available via subscription   (Followers: 29)
Advances in Tropical Biodiversity and Environmental Sciences     Open Access   (Followers: 5)
Advances in Virus Research     Full-text available via subscription   (Followers: 8)
Adversity and Resilience Science : Journal of Research and Practice     Hybrid Journal   (Followers: 3)
African Journal of Ecology     Hybrid Journal   (Followers: 18)
African Journal of Range & Forage Science     Hybrid Journal   (Followers: 12)
AFRREV STECH : An International Journal of Science and Technology     Open Access   (Followers: 3)
Ageing Research Reviews     Hybrid Journal   (Followers: 13)
Aggregate     Open Access   (Followers: 1)
Aging Cell     Open Access   (Followers: 22)
Agrokémia és Talajtan     Full-text available via subscription   (Followers: 2)
AJP Cell Physiology     Hybrid Journal   (Followers: 16)
AJP Endocrinology and Metabolism     Hybrid Journal   (Followers: 26)
AJP Lung Cellular and Molecular Physiology     Hybrid Journal   (Followers: 4)
Al-Kauniyah : Jurnal Biologi     Open Access  
Alasbimn Journal     Open Access   (Followers: 1)
Alces : A Journal Devoted to the Biology and Management of Moose     Open Access  
Alfarama Journal of Basic & Applied Sciences     Open Access   (Followers: 8)
All Life     Open Access   (Followers: 1)
AMB Express     Open Access   (Followers: 1)
Ambix     Hybrid Journal   (Followers: 3)
American Journal of Agricultural and Biological Sciences     Open Access   (Followers: 7)
American Journal of Bioethics     Hybrid Journal   (Followers: 18)
American Journal of Human Biology     Hybrid Journal   (Followers: 17)
American Journal of Medical and Biological Research     Open Access   (Followers: 4)
American Journal of Plant Sciences     Open Access   (Followers: 23)
American Journal of Primatology     Hybrid Journal   (Followers: 17)
American Naturalist     Full-text available via subscription   (Followers: 80)
Amphibia-Reptilia     Hybrid Journal   (Followers: 5)
Anaerobe     Hybrid Journal   (Followers: 3)
Analytical Methods     Hybrid Journal   (Followers: 8)
Analytical Science Advances     Open Access   (Followers: 1)
Anatomia     Open Access   (Followers: 12)
Anatomical Science International     Hybrid Journal   (Followers: 3)
Animal Cells and Systems     Hybrid Journal   (Followers: 5)
Animal Microbiome     Open Access   (Followers: 3)
Animal Models and Experimental Medicine     Open Access  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 2)
Annales Henri Poincaré     Hybrid Journal   (Followers: 2)
Annales Universitatis Mariae Curie-Sklodowska, sectio C – Biologia     Open Access   (Followers: 1)
Annals of Applied Biology     Hybrid Journal   (Followers: 6)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 18)
Annals of Human Biology     Hybrid Journal   (Followers: 5)
Annals of Science and Technology     Open Access   (Followers: 2)
Annual Research & Review in Biology     Open Access  
Annual Review of Biomedical Engineering     Full-text available via subscription   (Followers: 18)
Annual Review of Biophysics     Full-text available via subscription   (Followers: 24)
Annual Review of Cancer Biology     Full-text available via subscription   (Followers: 3)
Annual Review of Cell and Developmental Biology     Full-text available via subscription   (Followers: 44)
Annual Review of Food Science and Technology     Full-text available via subscription   (Followers: 13)
Annual Review of Genomics and Human Genetics     Full-text available via subscription   (Followers: 31)
Annual Review of Phytopathology     Full-text available via subscription   (Followers: 11)
Anthropological Review     Open Access   (Followers: 28)
Antibiotics     Open Access   (Followers: 12)
Antioxidants     Open Access   (Followers: 4)
Antioxidants & Redox Signaling     Hybrid Journal   (Followers: 8)
Antonie van Leeuwenhoek     Hybrid Journal   (Followers: 3)
Anzeiger für Schädlingskunde     Hybrid Journal   (Followers: 1)
Apidologie     Hybrid Journal   (Followers: 4)
Apmis     Hybrid Journal   (Followers: 1)
APOPTOSIS     Hybrid Journal   (Followers: 8)
Applied Biology     Open Access  
Applied Bionics and Biomechanics     Open Access   (Followers: 4)
Applied Phycology     Open Access  
Applied Vegetation Science     Full-text available via subscription   (Followers: 9)
Aquaculture Environment Interactions     Open Access   (Followers: 7)
Aquaculture International     Hybrid Journal   (Followers: 25)
Aquaculture Reports     Open Access   (Followers: 3)
Aquaculture, Aquarium, Conservation & Legislation - International Journal of the Bioflux Society     Open Access   (Followers: 9)
Aquatic Biology     Open Access   (Followers: 9)
Aquatic Ecology     Hybrid Journal   (Followers: 42)
Aquatic Ecosystem Health & Management     Hybrid Journal   (Followers: 16)
Aquatic Science and Technology     Open Access   (Followers: 4)
Aquatic Toxicology     Hybrid Journal   (Followers: 26)
Arabian Journal of Scientific Research / المجلة العربية للبحث العلمي     Open Access  
Archaea     Open Access   (Followers: 3)
Archiv für Molluskenkunde: International Journal of Malacology     Full-text available via subscription   (Followers: 1)
Archives of Biological Sciences     Open Access  
Archives of Microbiology     Hybrid Journal   (Followers: 9)
Archives of Natural History     Hybrid Journal   (Followers: 8)
Archives of Oral Biology     Hybrid Journal   (Followers: 2)
Archives of Virology     Hybrid Journal   (Followers: 6)
Archivum Immunologiae et Therapiae Experimentalis     Hybrid Journal   (Followers: 2)
Arctic     Open Access   (Followers: 8)
Arid Ecosystems     Hybrid Journal   (Followers: 2)
Arquivos do Instituto Biológico     Open Access   (Followers: 1)
Arquivos do Museu Dinâmico Interdisciplinar     Open Access  
Arthropod Structure & Development     Hybrid Journal   (Followers: 2)
Arthropod Systematics & Phylogeny     Open Access   (Followers: 3)
Artificial DNA: PNA & XNA     Hybrid Journal   (Followers: 2)
Artificial Intelligence in the Life Sciences     Open Access  
Asian Bioethics Review     Full-text available via subscription   (Followers: 2)
Asian Journal of Biological Sciences     Open Access   (Followers: 2)
Asian Journal of Biology     Open Access  
Asian Journal of Biotechnology and Bioresource Technology     Open Access  
Asian Journal of Cell Biology     Open Access   (Followers: 4)
Asian Journal of Developmental Biology     Open Access   (Followers: 1)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 3)
Asian Journal of Nematology     Open Access   (Followers: 4)
Asian Journal of Poultry Science     Open Access   (Followers: 3)
Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche     Open Access  
Australian Life Scientist     Full-text available via subscription   (Followers: 2)
Australian Mammalogy     Hybrid Journal   (Followers: 8)
Autophagy     Hybrid Journal   (Followers: 8)
Avian Biology Research     Hybrid Journal   (Followers: 4)
Avian Conservation and Ecology     Open Access   (Followers: 17)
Bacterial Empire     Open Access   (Followers: 1)
Bacteriology Journal     Open Access   (Followers: 2)
Bacteriophage     Full-text available via subscription   (Followers: 2)
Bangladesh Journal of Bioethics     Open Access  
Bangladesh Journal of Plant Taxonomy     Open Access  
Bangladesh Journal of Scientific Research     Open Access  
Berita Biologi     Open Access  
Between the Species     Open Access   (Followers: 2)
BIO Web of Conferences     Open Access  
Bio-Grafía. Escritos sobre la Biología y su enseñanza     Open Access  
Bio-Lectura     Open Access  
BIO-SITE : Biologi dan Sains Terapan     Open Access  
Bioactive Compounds in Health and Disease     Open Access  
Biocatalysis and Biotransformation     Hybrid Journal   (Followers: 5)
BioCentury Innovations     Full-text available via subscription   (Followers: 2)
Biochemistry and Cell Biology     Hybrid Journal   (Followers: 18)
Biochimie     Hybrid Journal   (Followers: 4)
BioControl     Hybrid Journal   (Followers: 2)
Biocontrol Science and Technology     Hybrid Journal   (Followers: 5)
Biodemography and Social Biology     Hybrid Journal   (Followers: 1)
BIODIK : Jurnal Ilmiah Pendidikan Biologi     Open Access  
BioDiscovery     Open Access   (Followers: 2)
Biodiversitas : Journal of Biological Diversity     Open Access   (Followers: 2)
Biodiversity : Research and Conservation     Open Access   (Followers: 30)
Biodiversity Data Journal     Open Access   (Followers: 8)
Biodiversity Informatics     Open Access   (Followers: 3)
Biodiversity Information Science and Standards     Open Access   (Followers: 2)
Biodiversity Observations     Open Access   (Followers: 2)
Bioeduca : Journal of Biology Education     Open Access   (Followers: 1)
Bioeduscience     Open Access   (Followers: 2)
Bioeksperimen : Jurnal Penelitian Biologi     Open Access  
Bioelectrochemistry     Hybrid Journal   (Followers: 1)
Bioelectromagnetics     Hybrid Journal   (Followers: 1)
Bioenergy Research     Hybrid Journal   (Followers: 3)
Bioengineering and Bioscience     Open Access   (Followers: 1)
BioEssays     Hybrid Journal   (Followers: 11)
Bioethica     Open Access   (Followers: 1)
Bioethics     Hybrid Journal   (Followers: 21)
BioéthiqueOnline     Open Access   (Followers: 1)
Biogeographia : The Journal of Integrative Biogeography     Open Access   (Followers: 2)
Biogeosciences (BG)     Open Access   (Followers: 17)
Biogeosciences Discussions (BGD)     Open Access   (Followers: 4)
Bioinformatics     Hybrid Journal   (Followers: 283)
Bioinformatics Advances : Journal of the International Society for Computational Biology     Open Access   (Followers: 3)
Bioinformatics and Biology Insights     Open Access   (Followers: 13)
Biointerphases     Open Access   (Followers: 1)
Biojournal of Science and Technology     Open Access  
BioLink : Jurnal Biologi Lingkungan, Industri, Kesehatan     Open Access  
Biologia     Hybrid Journal   (Followers: 1)
Biologia Futura     Hybrid Journal  
Biologia on-line : Revista de divulgació de la Facultat de Biologia     Open Access  
Biological Bulletin     Partially Free   (Followers: 6)
Biological Control     Hybrid Journal   (Followers: 6)

        1 2 3 4 5 6 7 8 | Last

Similar Journals
Journal Cover
Advances in Cell Biology/ Medical Journal of Cell Biology
Number of Followers: 26  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2080-2218
Published by Sciendo Homepage  [389 journals]
  • Expression of selected cytokeratins in human placenta - a preliminary
           observational study

    • Abstract: Every human body is made up of billions of cells, and every cell consists of thousands of microscopic structures. Thanks to the presence of the cytoskeleton, which is built by microfilaments, microtubules, and intermediate filaments, cells are able to fulfill their main function. Dozens of genes encode a large family of cytoskeletal proteins, which form 10-nanometer-long microfilaments, called cytokeratins.The study was carried out on seven mature human placentas without significant pathology - all eligible mothers were healthy. The collection of basic anthropometric data preceded the dissection of the placentas. Paraffin blocks were made in the usual manner, and hematoxylin and eosin-stained slides were made afterward. Immunohistochemical reactions were performed and the expression of the studied markers was evaluated independently by two observers.Evaluation of microscopic material revealed the absence of expression of antibodies for cytokeratin 5/6 in placental tissues. Moreover, strong expression of cytokeratin 7 was demonstrated in the villi trophoblast in all types of villi. Immunohistochemical reactions were observed in the mesenchyme within the blood vessel wall, as well as in the extravascular tissue.The human placenta is an organ that only exists during the intrauterine period of human development and undergoes rapid changes and dynamic growth during pregnancy. These types of processes define selected placental cells as ‘pseudo-tumorigenic tissue’ because of the numerous similarities trophoblast cells have to tumor cells. The use of tissue microarray (TMA) in combination with immunohistochemistry (IHC) may be a valuable approach to validate the predictive and diagnostic utility of various biomarkers in non-cancerous tissues like placental tissue.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • The effect of physical activity on gut microbiota. A review

    • Abstract: This review examines how physical activity can modulate the gut microbiota, taking into account the training intensity used, the value of the load and the age group studied. The aim of the study is to show the significant interaction between exercise and its effects on the gut microbiota. Many of the studies we analysed showed an interesting correlation between the physical activity undertaken and the change in biodiversity and taxon representation, so we concluded that exercise can significantly modulate the composition of the gut microbiome. This also works the other way around, as doing too much intense and taxing exercise can lead to so-called intestinal dysbiosis, which promotes inflammatory reactions and other unfavourable metabolic consequences. Therefore, in this review, we have analysed the latest and most interesting body of literature oscillating around the complex relationship between the movement undertaken and its impact on the microbiome.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • Do taller people live longer' Evaluating the relationship between
           adult stature and longevity

    • Abstract: Body height is positively correlated with overall health and survival. Previous studies have found that taller people are healthier and live longer than their smaller counterparts. Despite numerous investigations, the correlation between adult stature and longevity remains uncertain. The objective of the present study is to evaluate the relationship between adult height and lifespan. Data were available from 480493 men and 364666 women who died in the years 2004-2008 in Poland. Pearson’s r coefficients of correlation were calculated and ANOVA was employed. The correlation between height and longevity was negative and statistically significant in men (r = –0.27, p < 0.0001) and women (r = –0.25, p < 0.0001). However, after allowing for the cohort effect, these correlations proved to be very weak and significant. On balance, these results do not corroborate the hypothesis that taller people live longer, and the effects of body height on survival were small. In this article, these findings are discussed in an attempt to identify the biological mechanisms that are responsible for greater longevity in short people. This paper also deals with several biological factors and mechanisms involved in the link between body size and longevity.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • Trigger points in medical practice - current therapeutic directions

    • Abstract: Recent scientific evidence suggests that one of the causes of myofascial pain syndromes responsible for the occurrence of chronic headaches, among other things, may be increased or impaired with trigger point therapy.This paper presents the results of a non-systematic literature review on trigger point therapy.The analysis shows a clear increase in scientific interest in invasive trigger point pain treatment techniques. Invasive therapy consists primarily of the use of injections and dry needling. Injections of anesthetics or botulinum toxin are methods that, in addition to their possible therapeutic effect, may carry side effects. In contrast, dry needling does not have a fully scientifically-proven effect. Recent scientific data also indicates that the aforementioned method may have a limited clinical effect.The performed analysis did not demonstrate a significant advantage in invasive techniques over typical non-invasive techniques. It is therefore necessary to design randomized multi-center clinical trials to definitively verify the efficacy of these techniques in the treatment of tension-type trigger point-dependent myofascial pain.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • Cadaver preserving methods – is it possible to do anything
           better'

    • Abstract: It is impossible to imagine learning anatomy without properly fixating cadavers. Thanks to accurate preservation techniques, students can differentiate anatomical structures by their sight and touch. The formalin method was first described almost 150 years ago, and as such it may seem primitive, however it is effective and easy to use, which is why it is still in use today. Despite formaldehyde’s bactericidal, fungicidal, and insecticidal properties contact with vapors of embalming solutions such as formalin may have a negative health effect. Skin drying, eczema, allergic contact dermatitis and lowered red blood cells (RBCs) and platelets are only a few symptoms that may occur as a result of spending long periods of time in places where cadavers are stored.Due to formalin’s features, other techniques were invented. Thiel’s method is also well known; after liquid application, tissues remain their natural color as the method is non-irritating and almost odorless. With the rise of technology, more modern methods of cadaver preservation were developed as alternative to formalin, such as the use of N-vinyl-2-pyrrolidone (NVP), which is commonly implemented in Japan and Brazil, and the Modified Larssen solution (MLS), which gives the possibility to reduce formalin concentration without losing the effectiveness of tissue preservation.The aim of this work is to develop an integrated approach to cadaver preservation through the analysis of frequently used preservation techniques. This is a considerable issue because first-year students of medicine and related faculties encounter the preserved material while learning anatomy.In comparison to more modern methods, formalin seems to be the worst choice due to worse joint flexibility, tissue colour and structure and, most importantly, its cancerogenic action.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • Pelvic floor muscle morphology and its impact on urinary incontinence and
           faecal incontinence

    • Abstract: Health problems related to pelvic floor muscles, as faecal incontinence (FI), urinary incontinence (UI) and constipation have a significant negative impact on a person’s life. The disease is accompanied by a serious symptoms, which exclude the patient from the local community. It is noteworthy that FI and UI involve increased financial outlays for the treatment of these disorders.Definition of the faecal incontinence is an uncontrolled passage of faecal materials that has occurred at least two to four times within four weeks of the last six months.Anatomy of pelvic fundus is strictly corelated with those diseases, because ability to contract and relax the muscles of the pelvic floor helps with the body’s daily basic functions.Risk factors of FI/UI include age, gender, comorbidities such as diabetes and irritable bowel syndrome, and obstetric factors. It could be treated with physiotherapy, pharmacotherapy or invasive treatment.A review of the literature indicates that the problem of FI/UI is a significant clinical issue of concern to clinicians due to very limited treatment techniques. There is a lack of primary research covering this issue in the world literature. The authors of this paper therefore believe that a holistic view of the subject based on the latest scientific data is necessary.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • Expression profile of genes regulating cellular response to cytokine
           stimulus in Sjögren’s syndrome

    • Abstract: The existence of abnormal cytokine profile in Sjögren’s syndrome (SS) may contribute to find potential SS biomarkers and accompanying comorbidities. We aimed to investigate and compare gene expressions in the labial salivary glands of SS and of healthy subjects (HS) by means of microarray analysis. The study group comprised 8 SS patients and 8 HS in microarray analysis. The relative gene expression changes were validated with real time quantitative polymerase chain reaction in 25 SS and 20 HS. Among the differently expressed genes belonging to the “cellular response to cytokine stimulus”, “cytokine-mediated signaling pathway” and “innate immune response” ontology groups with a fold change >1.5 and with a p value < 0.05, the adiponectin, C1Q and collagen domain containing (ADIPOQ), S100 calcium binding protein A9 (S100A9), leptin receptor (LEPR), and fatty acid binding protein 4 (FABP4) gene expressions in SS group were higher than in HS. Increased expression of the assessed genes are determined by the presence of SS and the accompanying inflammation and may be a valuable diagnostic biomarker of SS. Their selected systemic effects may suggest their role as potential prognostic biomarkers of the risk of accelerated atherosclerosis and cardiovascular complications in SS.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • Anatomical and medical terminology: new challenges and perspectives

    • Abstract: In science and medicine, terminology is a precise system of terms that are generally accepted in a given discipline. In anatomy, it is important to distinguish between terminology and nomenclature, which is an officially accepted set of terms arranged according to certain rules and principles. The Terminologia Anatomica (1998) has been the golden standard in the field of terminology, even though it contains minor errors, inaccuracies, discrepancies, multiplication of terms, inconvenient terms as well as synonyms and identical names for different structures. All of these problems need to be solved in the future, which is a key cchallenge in the field. Another major challenge is to create a clear, precise, logical, flawless and worldwide accepted list of anatomical terms that would cover all the names that are used in education and clinical practice. Many researchers and clinicians assert that this task is still ahead of us. The aim of this article is to explain why the longstanding tradition of medical terminology should be respected and why major and rapid changes should never be endorsed. Anatomical terminology, if correctly used, is a basic tool of communication both within and outside the field. It is also a guide through the intricacies of the human anatomy.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • Human ovarian follicular granulosa cells isolated during ART procedure
           reflect substantial changes in activation of hormonal signaling pathways,
           during long-term in vitro conditions

    • Abstract: The ovary is commonly known as an endocrine gland responsible for sex steroid production. One of the outstanding cells in ovarian microenvironment - granulosa cells (GCs) are responsible for converting the androgens to estrogens during follicular growth and secreting progesterone after ovulation. These secretory processes within the ovary are directly involved in hormonal signaling pathways, and they depend on different stages of cholesterol and lipid biosynthesis during the ovarian cycle. The understating of the regulation and further investigation into the processes taking part in ovary will expose new clinical advantages in detection and treatment of female reproductive system diseases associated with sex hormone abnormalities. The expression of genes belonging to ontology groups associated with steroid biosynthesis and metabolism, such as “cholesterol biosynthetic process” (GO:0006695, “regulation of lipid biosynthetic process” (GO:0046890), “regulation of lipid metabolic process” (GO:0019216), “response to insulin” (GO:0032868) and “response to lipopolysaccharide” (GO:0032496) were analyzed by using the microarray approach. The patterns of gene expression in human GCs at days 1-day, 7-day, 15-day, and 30-day of primary in vitro culture have been analyzed. Based on the microarray results, a group of upregulated genes have been selected: CCL20, CXCL5, STAR, MSMO1, and AADAC. The genes STAT5B, OPA3, PPARG, PROX1, and SEC14L2 were decreased across all the experimental groups during the 30-day cell cultivation period. These results suggest that, the GCs in cell culture under in vitro express steroidogenic markers and it is important to understand associations with lipid and liposaccharide synthesis relative to reproductive medicine.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • Changes in the frequency of ABO and Rh blood group phenotypes in Polish
           donors from Lower Silesia

    • Abstract: The aim of this study was to explore temporal and spatial variability of the frequency of the ABO and Rhesus blood group phenotypes in Polish donors from Lower Silesia between 1946 and 1990. Data on 158,134 individuals (113,714 men and 44,420 women) were obtained from two databases containing information about blood donors from Lower Silesia. The rate and direction of changes in the frequency of the blood groups were evaluated with regression analysis and Pearson’s correlation coefficient. Significant differences in the frequencies were found for the analysed period. The largest differences were observed for A and O blood groups. A significant increase in the frequency of the A group and a decrease in the O group were noted. The incidence of the AB group in both sexes did not change significantly. However, an insignificant decreasing trend in the frequency of the AB group in men was observed. An opposite and significant trend for this blood type was found in women. For the B group, the increase was significant in both sexes but it was greater in men. A significant increase in the frequency of the Rh(+) factor was noted. These results suggest that there were minor differences in the frequencies of ABO and Rh blood groups between the counties. This study demonstrated microevolutionary changes, thereby contributing new information to the field. These findings can be useful for the management of blood banks and the interpretation of microevolutionary changes.
      PubDate: Fri, 28 Apr 2023 00:00:00 GMT
       
  • Anatomy of the coronary arteries in Eurasian wild boar ()

    • Abstract: Coronary circulation determines the proper functioning of the heart muscle and blood circulation in the body. Cardiovascular diseases in humans are creating an ever-increasing demand for more research into their pathogenesis, diagnosis and treatment.Animal models of organs are an indispensable part of research for the development of human medicine. Due to the high genetic similarity, the most commonly used donor is the domestic pig. The Eurasian wild boar is the ancestor of the domestic pig and an invasive species not covered by European protection programmes. Given its analogous structure and genotype to the pig, it could potentially also become an organ donor.The aim of this study was to analyse the normal coronary anatomy of the Eurasian wild boar and compare it to humans, domestic pigs and other animal species.The study was conducted on 60 wild boar hearts. Twenty-eight slides were prepared using acrylic, while liquid latex was injected into 32 hearts. The blood vessels were then manually prepared using surgical instruments for examination.Both the right coronary artery and the left coronary artery of the boar diverge from the ascending aorta from opposite aortic sinuses. The left coronary artery begins its course in the left aortic sinus, starting between the left appendage and the pulmonary trunk. It then heads inferiorly. The right coronary artery supplies blood to the right atrium and right ventricle.The study points to the wild boar coronary system’s individual morphological features and notes the common arterial patterns in mammals.
      PubDate: Fri, 30 Sep 2022 00:00:00 GMT
       
  • In vitro evaluation of biocompatibility of two intracanal medicaments on
           stem cells from apical papilla – a comparative study

    • Abstract: The study explore some of the factors showing the biocompatibility and cellular metabolism of stem cells from apical papilla after their treatment with hapten solutions of two intracanal medicaments - Hydrocal and Acroseal. The MTT test and Annexin V test are used and the levels of HMOX-1 and IDO monitored after 48 hours of incubation in hapten solutions. In addition to proliferation and apoptosis, the possible sensitizing potential of these dental materials is assessed. The results show that after 48 hours, the groups treated with dental haptens found significantly fewer living cells than in the control group, which is especially indicative in the case of Acroseal. The proliferative activity of stem cells is increased, but without significant differences. HMOX-1 was statistically elevated in the Acroseal-treated group, indicative of its sensitizing capacity. IDO is statistically elevated in the group of cells treated with Hydrocal, which unequivocally speaks of the serious oxidative stress up to 48 hours and the need for protective action of this enzyme.
      PubDate: Fri, 30 Sep 2022 00:00:00 GMT
       
  • Features of the flexor retinaculum and its individual variation in carpal
           tunnel syndrome predisposition - a systematic review

    • Abstract: The flexor retinaculum is a structure located in the wrist, which spreads between the bones forming the carpal tunnel. Its task is to maintain the relative stabilization and protection of incorporated structures. It is also an attachment for the thenar muscles, causing biomechanical interactions in the wrist. Pathologies occurring in the carpal tunnel structures often cause pressure increase, leading to compression of the median nerve, causing carpal tunnel syndrome (CTS). This work aims to review literature knowledge and compile research outcomes in the PubMED and Google scholar databases.The results indicate the variability in size and aspects of flexor retinaculum due to gender, and the relationship between gender and the incidence of CTS. The data also show the flexor retinaculum’s molecular variability and environmental factors’ potential impact on these changes. This article demonstrates how anatomical conditions and physical features influence CTS development.
      PubDate: Fri, 30 Sep 2022 00:00:00 GMT
       
  • ELABELA as a Marker of Gestational Complications – A Review

    • Abstract: Adipose tissue secretes dozens of biologically active molecules known as adipokines or adipocytokines. Apelin receptor early endogenous ligand (ELABELA, also known as ELA or APELA) is a circulating signaling protein expressed in placental tissue that binds to apelin receptors. The first animal experimental findings suggested that the ELABELA deficiency might be responsible for the pathogenesis of preeclampsia--like symptoms, i.e., hypertension and proteinuria in mice. Exogenous ELABELA supplementation reverted preeclampsia symptoms and normalized fetal birth weight in mice. Several in vitro studies confirmed that ELABELA supplementation could improve trophoblast cell functions such as invasiveness and proliferation capacity. Thus, the ELABELA axis could serve as the target of innovative therapies for gestational complications. Nonetheless, most human studies do not support the thesis that disturbances in ELABELA secretion in early pregnancy are associated with an increased risk of preeclampsia. Therefore, it is unlikely that ELABELA could serve as a novel early marker of preeclampsia in humans. Alterations in the ELABELA secretion have also been discovered among patients with other gestational complications such as GDM and fetal growth restriction.
      PubDate: Sat, 09 Jul 2022 00:00:00 GMT
       
  • Heavy Eye Syndrome – Case Report

    • Abstract: This paper aims to report clinical features, differential diagnosis and successful surgical outcome of a patient with myopic strabismus fixus, also known as Heavy Eye syndrome (HES). We present a case of a 47-year-old man who presented to the Ophthalmology Department with diplopia and poor vision. In the past, he had been diagnosed with Graves’ disease, high myopia, and secondary open-angle glaucoma. He had undergone orbital decompression and cataract surgery of both eyes. On examination, the patient had esotropia and hypotropia with limited abduction and elevation. The patient was ultimately diagnosed with HES. Yokoyama’s surgery combined with a medial rectus muscle recession in the right eye, were performed. The procedure reduced esotropia, hypotropia and improved ductions.
      PubDate: Sat, 09 Jul 2022 00:00:00 GMT
       
  • Potential Role of LYN, CCL2, ITGB3 and IL6 Genes in the Immune Response of
           Porcine Buccal Mucosa Cells

    • Abstract: The genes considered in this study, namely, LYN, CCL2, ITGB3 and IL6 can be related to immune response in porcine buccal mucosa cells primary cultured in vitro. These genes are also responsible for, inter alia, cell migration, differentiation, proliferation and apoptosis, intracellular signal transduction, extracellular matrix binding and wound healing. A total of 20 pubertal crossbred Landrace gilts bred on commercial farms were used to obtain buccal mucosa cell cultures, which were harvested on the 7th, 15th and 30th day after initiation of the culture. Expression levels of LYN, CCL2, ITGB3 and IL6 were evaluated employing Real-Time Quantitative Polymerase Chain Reaction. All studied genes showed expression. The expression of CCL2 on day 15 was the highest of all factors measured. The greatest difference between the measurements occurred in gene IL6, between 7th and 15th day, while the least difference between the measurements occurred in gene LYN, between 7th and 15th day. Moreover, on the 7th day, LYN presented the lowest expression among all studied genes. Although in vitro conditions are much more controlled than in vivo conditions, all the factors that may positively or negatively affect cultured cells still cannot be fully predicted. Nevertheless, LYN, CCL2, ITGB3 and IL6 are a valuable starting point for studying further immunological processes in oral mucosal epithelial cells. Given their high regenerative potential, research into them is a highly valuable source of information for future wound healing therapies, where immunological processes should be carefully considered.
      PubDate: Sat, 09 Jul 2022 00:00:00 GMT
       
  • The Influence of L-Methionine, DL-Methionine, and a Methionine Hydroxy
           Analog on Proliferation and Differentiation Potential of Avian Myoblasts

    • Abstract: Methionine is an essential amino critical to many cell functions including the synthesis of proteins. Supplementation of methionine in vivo is typically through L-methionine, DL-methionine, or a methionine hydroxy analog (MHA). The goal of this study was to compare the function of L-methionine, DL-methionine, and an MHA as a source of methionine to myoblasts in vitro. Avian myoblasts isolated from turkey embryos were plated in media containing varying concentrations of DL-methionine (DLM; 1.125 mg/mL or 0.56 mg/mL) or methionine hydroxy analog (MHA; 1.28 mg/mL or 0.64 mg/mL) as well as a methionine deficient negative control group and an L-methionine supplemented positive control group. The results of the proliferation assay exhibited cell division in the absence of methionine which was not significantly different than the positive control group. Results from the myoblast fusion assay revealed significantly greater myotube diameter between methionine supplemented groups compared to the methionine deficient negative control. The findings of this study show an ability for avian myoblasts to proliferate in the absence of methionine, the significance of which is discussed. Additionally, findings from the fusion assay suggest that DL-methionine and MHA are potential cost-effective substitutes for methionine supplementation during terminal differentiation of avian myoblasts.
      PubDate: Sat, 09 Jul 2022 00:00:00 GMT
       
  • Ocular Manifestations of Pediatric Inflammatory Multisystem Syndrome

    • Abstract: This article aims to present up-to-date information on ocular symptoms of pediatric multi-system inflammatory syndrome. The reviewers obtained the results based on a search of an electronic database. The pediatric multi-system inflammatory syndrome appears a few weeks after COVID-19 in children. The exact etiology remains unclear. It is diagnosed based on clinical and laboratory criteria. The most prevalent manifestation of the syndrome is non-purulent conjunctivitis (observed in around 50% of cases). The other ocular findings in the pediatric multi-system inflammatory syndrome can be; eyelid swelling, bilateral uveitis or vitreous hyperreflective dots in the posterior vitreous. The treatment of the ophthalmic symptoms is systemic and topical, targeting the enhanced inflammatory response of the organism and the presence of the given ocular findings.
      PubDate: Sat, 09 Jul 2022 00:00:00 GMT
       
  • Difficulties in Treatment of Iridocorneal Endothelial Syndrome - Case
           Report

    • Abstract: The iridocorneal endothelial syndrome manifests in three clinical types: Chandler syndrome, progressive iris atrophy, and Cogan-Reese syndrome. It is caused by the presence of abnormal corneal endothelium on the iris stroma and anterior chamber angle leading to usually unilateral, progressive iris atrophy, glaucoma, and/or corneal edema. The etiology is yet unclear. It affects mostly young adults, mostly females. Management of iridocorneal endothelial syndrome is complex: conservative and surgical, depending on the stage of the disease and intensity of present symptoms. A 30-year-old female with a medical history of the iridocorneal endothelial syndrome was reported to the Ophthalmology Department for consultation. Slit-lamp examination revealed iris atrophy and superior-nasal corectopia in the left eye. On gonioscopy, the angle was wide open in the right eye, but there were iridocorneal adhesions and incomplete angle-closure in the left eye. The patient was provided with maximum local therapy consisting of three anti-glaucoma medications. On later check-ups, the patient presented corneal edema and increased intraocular pressure. She was qualified to ExPress mini shunt trabeculectomy with mitomycin C. Two years later, a patient came to the clinic because of increased values of intraocular pressure (up to 59 mmHg), slit-lamp examination showed that the ExPress implant was congested with fragments of the corneal endothelial cells. Thanks to YAG iridotomy the implant was recanalized.
      PubDate: Sat, 09 Jul 2022 00:00:00 GMT
       
  • Current application of exosomes in medicine

    • Abstract: Exosomes are a distinct type of extracellular vesicles that play a major role in intracellular transport and communication. Depending on the cell of origin, exosomes can contain diverse constituents of a cell, including DNA, RNA, lipids, metabolites, cytosolic and cell-surface proteins, playing important roles in a wide range of physiological and pathological processes. Due to these facts, they are subject of extensive research aiming at translating the knowledge into clinical approaches that are at the interface between nanomedicine and biopharmaceuticals.Their potential clinical use mostly revolves around the fields of diagnostics and drug delivery, especially important in treatment of cancer. The conventional and emerging methods of exosome isolation are either based on their physical properties (such as density and/or size) or their functions. However, the isolation approaches are still characterised by significant downsides, lacking standardisation, and ensuring purity. The review gives a critical overview on exosomes characteristics, isolation approaches and the potential that exosomes hold in developing new clinical approaches of modern medicine, highlighting the need for further research to fully grasp their potential and translate the knowledge into future therapeutic solutions.
      PubDate: Sun, 10 Apr 2022 00:00:00 GMT
       
 
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