Authors:Alisara Sujarit, Papavadee Tungjitrungroj, Chonlawan Tunphanich, Chanya Tiempathom, Vidhavas La-orkhun Pages: 1 - 13 Abstract: The objective of this study was to examine factors affecting effectiveness and safety of warfarin in pediatric patients. This retrospective descriptive study was conducted at King Chulalongkorn Memorial Hospital. The clinical and medication-related data of patients aged 1-18 years, receiving warfarin between January 2015 and December 2020 were collected. Data were analyzed by descriptive statistics and multiple logistic regression. A total of 102 pediatric patients, the result showed that pediatric patients who did not have any surgery during warfarin treatment have by 9.67 times the odds of having the percentage of Time in Therapeutic Range (%TTR) more than 65, compared to patients that have surgery by adjusted with gender, age, weight, drug-drug interactions and non-compliance (adjusted OR 9.67, p=0.037). Moreover, TTR is lower than the therapeutic target (median: 38.3; IQR: 21.4, 67.4). However, this study found thromboembolism only 2 patients and only one patients of major bleeding. In conclusion, surgery during warfarin treatment in pediatric patients is important factor that affects the percentage of Time in Therapeutic Range that may affects to effectiveness and safety of pediatric patients using warfarin. PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Ratchaneekorn Katchama, Phatcharee Srikuta Pages: 14 - 27 Abstract: This cross-sectional analytical study aims to study health literacy in malaria prevention, malaria prevention behavior and the relationship between health literacy in malaria prevention and malaria prevention behavior of people in risk areas. The samples used in the research were people in risk areas of Nakhon Ratchasima province. A total of 385 people came from cluster sampling and simple random sampling, and data collection was by questionnaire. Data were analyzed using descriptive statistics and multiple logistic regression analysis with enter method. The results showed that most of the samples had insufficient levels of health literacy in malaria prevention at 89.1% and inappropriate levels of malaria prevention behavior at 70.9%. After controlling the confounding factors, the results also show that health literacy in malaria prevention was significantly associated with malaria prevention behavior (P-value <0.001). The sample with sufficient health literacy in malaria prevention has up to 4.095 times more proper malaria prevention behavior than a sample with insufficient levels of health literacy in malaria prevention (95% CI = 2.067-8.115). PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Apichit Sathawornwiwat, Suttisa Chanpeng, Prasong Kitidamrongsuk, Vallerut Pobkeeree Pages: 28 - 41 Abstract: This cross - sectional analytic survey research aims to analyze the level of workplace happiness, and relationship between demographic characteristics and workplace happiness in working staff of a community hospital. The workplace happiness questionnaire was adapted from the Happinometer, developed by the Institute for Population and Social Research, Mahidol University. Reliability of questionnaires was 0.775. The subjects included everyone in the hospital. Data analysis was done through chi-square. The result showed that overall degree of happiness at work was happy. The highest mean of happiness dimension was Happy family (87%), and the lowest mean dimension was Happy health (58%). Workplace happiness was statistically related to age and education (p-value < 0.05). There was no statistical relationship between gender, marital status, having child or children, job type, employment status, work duration, family income and workplace happiness at the hospital. The result of this study could be used to create happiness at work in a community hospital staff, such as a period of activity happiness can be created at the beginning of the period of work, sharing experience of senior personnel with others, encouraging exercise, designing specific activities for below bachelor degree group and postgraduate level group. PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Worapong Paduka, Thanakon Chanuwong, Orapa Sillamut, Pavin Suwannakul, Lin Yu Sheng Pages: 42 - 54 Abstract: This research study aimed to study the efficacy of Chinese herbal ointments for treating chronic pain, especially pain in the elderly in Bang Chalong Subdistrict, Bang Phli District, Samut Prakan Province, using the formula "Xue Fu Zhu Yu" by a two-group comparison study. Data were collected before and after the experiment (clinical control-trial group). The groups consisted of elderly people in Bang Phli District in Samut Prakan Province. Those diagnosed by traditional Chinese medicine were among 67 patients with thrombophlebitis, including 34 females and 33 males. In the experimental group there were 18 females and 15 males and a total of 33 cases: mean age 66.81 years, mean body mass index (BMI) 24.47 kg/m2, and in the control group: 16 females, 18 males, total 34 cases, mean age 68.35 years, mean body mass index (BMI) 24.31 kg/m2. Both groups received 1 jar of herbal ointment each, applied and lightly massaged to the affected area twice daily (morning and bedtime) for a period of one week. Evaluation was done by using a record form. The results showed that there was no statistically significant difference in age, body mass index, work activity, and pain before treatment between the two groups (p>0.05 ). There was a statistically significant difference in pain reduction (p<0.05 ) in the experimental group within one week, and there was no statistically significant difference in pain before and after treatment (p>0.05 ) Comparison of syndromes in Chinese medicine found that there were no statistically significant differences between the two groups before and after treatment (p>0.05 ). PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Watcharin Rangsipanuratn, Patcharee Kammarnjassadakul, Puttipong Ratana, Wararat Masalae, Pennapa Chamavit, Sucha Chulsamlee, Panupong Sahaisook Pages: 55 - 64 Abstract: This preliminary study aimed to survey the prevalence of extended-spectrum b-lactamase (ESBL)-producing Enterobacterales from cockroach intestines. A total of 55 cockroaches were collected from households in community housing, Samut Prakan province and further identified. All guts were cultured on selective and differential agar for bacterial isolation. The bacterial species were identified by using biochemical media or MALDI-TOF Mass Spectrometry and further identified for ESBL production by phenotypic and genotypic methods. The result showed that all cockroaches were American cockroaches (Periplaneta americana). Medically significant bacteria were isolated from the intestines of 100% of cockroaches. The top three bacterial species identified were Citrobacter freundii, Escherichia coli, and Klebsiella pneumoniae (30.67, 17.33, and 12.0%, respectively). ESBL expression was detected in one strain of C. freundii and confirmed to be blaVEB by PCR, representing a prevalence of 1.33%. In conclusion, P. americana is considered a potential carrier and a vector of pathogenic bacteria, especially transmission of ESBL-producing Enterobacterales. PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Piyawan Wongboonnak, Sasiwan Anankawanit, Papimol Phuaksanit, Siripansa Chaichudchaval Pages: 65 - 77 Abstract: The objective was to study eHealth literacy and self-management in COVID-19 prevention and the relationship between eHealth literacy and self-management in COVID-19 prevention of the population in Bangkok, Nonthaburi, Pathum Thani, and Samut Prakan. This study used online self-administrative questionnaires as a tool to collect information. The 415 samples in this study were calculated using the Taro Yamane method. Data were collected from March to October 2020. The results found that the sample had an average score of eHealth literacy at 4.02 ± 0.70, a high level. For the gender differences, there was no difference in the level of eHealth literacy (p-value = 0.667). The age differences, education levels, and occupations had different levels of eHealth literacy (p-value < 0.001, 0.029, and 0.032, respectively). The self-management in COVID-19 protection of samples had an average score of 4.08 ± 0.59 which is a high level. The different ages had different levels of self-management in COVID-19 prevention (p-value = 0.012). The gender differences, education levels and occupations had no difference in self-management in COVID-19 prevention (p-value = 0.240, 0.494, and 0.103, respectively). The relationship between eHealth literacy and self-management in COVID-19 prevention from the analysis of Pearson correlation (r) of 0.277 (p-value < 0.001) showed a positive correlation meaning that if there were more eHealth literacy, there would have been good self-management on COVID-19 protection. PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Worrapannee Powtongsook, Watcharin Rangsipanuratn, Weerachai Tubchan, Parinya Semuang, Soramon Sutin, Saowaluck Meesin Pages: 78 - 90 Abstract: This study evaluated the efficacy of three Chinese herbs against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible Staphylococcus aureus (MSSA). The antioxidant, antibacterial and anti-biofilm formation of ethanol extract of three Chinese herbs including Huang Pai (Phellodendron chinensis Schneid), Da Huang (Rheum palmatum Linn.), and Ou Mei (Prunus mume (Sieb) Sieb. Et Zucc.) were evaluated. Results from antioxidant activity using DPPH radical scavenging assay showed that Da Huang had the best antioxidant with an IC50 (50% Inhibitory Concentration) value similar to the standard BHT (Butylated hydroxyl toluene). Results from the agar well diffusion and colorimetric broth microdilution tests revealed that crude extracts of Huang Pai and Da Huang had better activities than Ou Mei. The antimicrobial activity of Huang Pai against MSSA was higher than Da Huang as seen by the MIC (Minimum Inhibitory Concentration) value of 0.391 and 1.562 mg/ml, respectively. The anti-MRSA activity of both herbs’ extracts had a similar MIC value of 1.562 mg/ml. Huang Pai showed the most potent anti-biofilm effect against MSSA and MRSA with 80% inhibition of biofilm formation at 0.0244 and 0.0488 mg/ml, respectively. Results from this study illustrated that Huang Pai and Da Huang have the potential for further development into natural products treating of Staphylococcus aureus infection. PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Sirinun Kumsri, Chanapon Singsook, Yada Reamrimmadun, Woraphot Thamniab Pages: 91 - 106 Abstract: The purpose of this study was to study the result of the development of a workshop model on self-care behaviors for the elderly according to the Sufficiency Economy Philosophy at Pak Nam Municipality, Bang Khla District, Chachoengsao Province. The sample size of 30 people was calculated by Cohen's formula and used to analyze the power of the test. The period to conduct activities in self-care behaviors workshop for the elderly was 6 months. The activities according to the Sufficiency Economy Philosophy included moderation, reasonableness, and good self-immunity, knowledge condition and moral conditions. Data were collected by interview questionnaire and were analyzed by Paired – Samples T- Test. This study found that most of the sample were female, aged between 66 and 70 years old, with marital status, primary education level, income between 5,000 and 10,000 baht, source of income was received from spouse/children/relatives, and the expenses for self-care or illness were 1,000 to 3,000 baht per month. There was participation in the elderly club every time. The overall result of the workshop on the elderly self-care behavior according to the sufficiency economy philosophy before the experiment was 3.53 ± .44 or at a moderate level, and after the experiment it was 4.37±.17 or at a high level. Moreover, the behaviors after the workshop on elderly self-care had a significant statistical difference (p< 0.01). However, in terms of knowledge and experience conditions for self-care and to be applied to the practice of self-sufficient living, it should be linked to family members of the elderly as a supporting factor for success. PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Nittida Pataraterakul, Rungnapa Tengtrisorn, Khattiya Mangkang, Witchuta Petchoo, Jaturat Poonmongkon Pages: 107 - 117 Abstract: The objectives of this study were to explore the level of health literacy and examine the association between health literacy and the control of sugar levels in diabetic patients at Nongprue Health Promoting Hospital. Participants included 50 people with type 2 diabetes who were registered at Nongprue Health Promoting Hospital. A convenience sampling technique was adopted. Data were collected by using questionnaires that included general information and an assessment of health literacy from August 2020 to September 2020. The results showed that most of the participants were female (76%), and the mean age was 65.26 ± 10.10. Fasting blood sugar (£160 mg/dL) was controlled in 74% of type 2 diabetes patients. Overall, health literacy was fair (mean score: 41.51 10.74), with 46% having low health literacy. The well-controlled FBS patients had a higher level of health literacy than the poorly controlled group (mean scores of 43.71 ± 10.59 and 39.93 ± 7.75, respectively). Furthermore, diabetes patients over the age of 65 had higher mean scores than those under the age of 65 (43.72 ±8.24 vs. 39.78± 12.20, respectively). There was little correlation between health literacy and blood sugar control in diabetic patients over 65 years old (r -0.393, p < 0.05). Based on the results of this study, healthcare providers should plan activities or projects to improve health literacy in all areas and encourage self-care behaviors, especially in diabetic patients over 65 years old. PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Thantip Sanduang, Chanokporon Jitpanya, Sakuntala Anureung Pages: 118 - 134 Abstract: The purpose of this research was to study insomnia and relationships between fatigue, depression and insomnia in end stage renal disease patients undergoing hemodialysis. The study sample consisted of 123 end stage renal disease patients undergoing hemodialysis recruited by a purposive sampling. The instruments consisted of the demographic data form, the Fatigue Severity Scale, the Insomnia Severity Index and the depression scale. All instruments were tested for their content validity by 5 experts, and the content validity index was equal to .97, .94, and .97 respectively. Their reliability scores as calculated by Chronbach’s alpha coefficient were .97, .86 and .90, respectively. Descriptive statistics, and Pearson product moment correlation were used for statistical analysis. The results revealed that insomnia of end stage renal disease patients was at “subthreshold insomnia” (Mean=12.13, SD=7.87). Fatigue and depression were significantly and positively correlated with insomnia (r=.494, p<.001 and r=.633, p<.001, respectively) PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Chawisa Rattanakamonkarn, Piyarat Samantarath, Onanong Chawsarn, Suwaree Posri, Onanong Buala, Kanokporn Nateetanasombat, Aree Mungkietisakul, Buakaew Chidecharoen, Sudarat Simsen, Chaveewan Tangamatakul, Chidchanok Sittarstasak, Itsaree Luengwilai Pages: 135 - 146 Abstract: This quasi-experimental study with one-group pretest-posttest design was aimed to examine the effects of the program promoting self-efficacy for school age children on knowledge and skills related to first aid and basic life support. The samples were 30 Youth Village Health Volunteers chosen by the teachers from students in grade four through grade six at Watbangchalongnok school and Suraobangkasee school, Samutprakarn province. The data were collected during September to October 2019. The research instruments consisted of the program promoting self-efficacy in first aid and basic life support, the knowledge and skills related to first aid and basic life support assessment forms, developed by the researchers and were approved for content validity by three experts. The reliability of the knowledge assessment form using Kuder-Richardson Method was .78 and the skill assessment form using Cronbach’s alpha coefficient was .76. Data were analyzed using Paired t-test. The finding demonstrated after enrolled the program promoting self-efficacy for school age children, participants' scores on knowledge and skills related to first aid and basic life support were significantly higher, compared to before enrolling program (t= 12.07, p<.05 and t= 10.95, p<.05 respectively). The results of this study suggest that the program promoting self-efficacy for school age children enhance children's knowledge and skills related to first aid and basic life support. PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)
Authors:Chanthima Chuaichum, Yupin Meuntip Pages: 147 - 156 Abstract: Teaching and learning management with jigsaw technique is a learning activity using puzzle concept with group processes and communication skills. The teachers use to develop learners according to the 21st century education, to be a nursing graduate with desirable characteristics, able to study and gain knowledge on their own responsible and convey the content of knowledge to others correctly and appropriately for the situation. The teaching and learning management with jigsaw technique for the Bachelor of Science in Nursing program. There are steps to implement according to the roles and responsibilities of both instructors and learners starting from the preparation stage, teaching stage, conclusion stage, and evaluation stage, to enable to apply their knowledge to nursing practice according to the patient,s condition properly and appropriately. PubDate: 2023-05-27 Issue No:Vol. 27, No. 1 (2023)