Subjects -> EDUCATION (Total: 2507 journals)
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EDUCATION (2141 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 857 Journals sorted alphabetically
#Tear : Revista de Educação, Ciência e Tecnologia     Open Access   (Followers: 5)
(Pensamiento), (palabra) y obra     Open Access   (Followers: 4)
21st Century Pedagogy     Open Access   (Followers: 12)
@tic. revista d'innovació educativa     Open Access  
Abant İzzet Baysal Üniversitesi Eğitim Fakültesi Dergisi     Open Access   (Followers: 2)
ABDIMAS ALTRUIS : Jurnal Pengabdian Kepada Masyarakat     Open Access  
Abdimas Toddopuli : Jurnal Pengabdian Pada Masyarakat     Open Access   (Followers: 10)
About Campus     Hybrid Journal   (Followers: 9)
Academic Medicine     Hybrid Journal   (Followers: 82)
Academic Psychiatry     Full-text available via subscription   (Followers: 34)
Academic Questions     Hybrid Journal   (Followers: 9)
Academy of Management Learning and Education     Full-text available via subscription   (Followers: 68)
Accounting & Finance     Hybrid Journal   (Followers: 63)
Accounting Education: An International Journal     Hybrid Journal   (Followers: 25)
ACM Transactions on Computing Education (TOCE)     Hybrid Journal   (Followers: 14)
Acta Científica : Ciências Humanas     Open Access   (Followers: 2)
Acta Didactica Norge     Open Access   (Followers: 2)
Acta Educationis Generalis     Open Access   (Followers: 1)
Acta Paedagogica Vilnensia     Open Access   (Followers: 1)
Acta Scientiarum. Education     Open Access  
Action in Teacher Education     Hybrid Journal   (Followers: 91)
Action Learning: Research and Practice     Hybrid Journal   (Followers: 47)
Action Research     Hybrid Journal   (Followers: 53)
Active Learning in Higher Education     Hybrid Journal   (Followers: 399)
Actualidades Pedagógicas     Open Access  
Adelphi series     Hybrid Journal   (Followers: 14)
Adiyaman University Journal of Educational Sciences     Open Access   (Followers: 1)
Administração Educacional     Open Access  
Administration & Society     Hybrid Journal   (Followers: 18)
Administrative Science Quarterly     Full-text available via subscription   (Followers: 277)
Adult Education Quarterly     Hybrid Journal   (Followers: 263)
Advanced Education     Open Access   (Followers: 19)
Advances in Building Education     Open Access   (Followers: 8)
Advances in Health Sciences Education     Hybrid Journal   (Followers: 39)
Advances in High Energy Physics     Open Access   (Followers: 29)
Advances in School Mental Health Promotion     Partially Free   (Followers: 11)
AERA Open     Open Access   (Followers: 14)
Africa Education Review     Hybrid Journal   (Followers: 31)
African Journal of Chemical Education     Open Access   (Followers: 6)
African Journal of Educational Studies in Mathematics and Sciences     Full-text available via subscription   (Followers: 12)
African Journal of Health Professions Education     Open Access   (Followers: 7)
African Journal of Research in Mathematics, Science and Technology Education     Hybrid Journal   (Followers: 13)
African Journal of Teacher Education     Open Access   (Followers: 4)
Agora     Full-text available via subscription   (Followers: 6)
AGORA Magazine     Open Access   (Followers: 1)
Ahmad Dahlan Journal of English Studies     Open Access   (Followers: 4)
AIDS Education and Prevention     Full-text available via subscription   (Followers: 9)
Ainedidaktiikka     Open Access  
Akademos     Open Access   (Followers: 2)
AKSIOMA Journal of Mathematics Education     Open Access   (Followers: 4)
AKSIOMATIK : Jurnal Penelitian Pendidikan dan Pembelajaran Matematika     Open Access   (Followers: 1)
Aksis : Jurnal Pendidikan Bahasa dan Sastra Indonesia     Open Access  
Al-Athfaal : Jurnal Ilmiah Pendidikan Anak Usia Dini     Open Access   (Followers: 2)
Al-Bahith Journal     Open Access   (Followers: 1)
Al-Fikrah     Open Access   (Followers: 3)
Al-Idarah : Jurnal Kependidikan Islam     Open Access  
Al-Jabar : Jurnal Pendidikan Matematika     Open Access   (Followers: 1)
Al-Mudarris : Journal of Education     Open Access   (Followers: 3)
Al-Tadris : Jurnal Pendidikan Bahasa Arab     Open Access  
Al-Tadzkiyyah : Jurnal Pendidikan Islam     Open Access  
Al-Tanzim : Jurnal Manajemen Pendidikan Islam     Open Access  
Al.Qadisiya journal for the Sciences of Physical Education     Open Access  
Alberta Journal of Educational Research     Full-text available via subscription   (Followers: 9)
Aldaba     Open Access   (Followers: 1)
Alexandria : Revista de Educação em Ciência e Tecnologia     Open Access  
Alotrop     Open Access  
Alsic : Apprentissage des Langues et Systèmes d'Information et de Communication     Open Access   (Followers: 18)
Alteridad     Open Access  
Ambiente & Educação : Revista de Educação Ambiental     Open Access  
American Annals of the Deaf     Full-text available via subscription   (Followers: 16)
American Educational Research Journal     Hybrid Journal   (Followers: 260)
American Journal of Business Education     Open Access   (Followers: 17)
American Journal of Distance Education     Hybrid Journal   (Followers: 35)
American Journal of Education     Full-text available via subscription   (Followers: 295)
American Journal of Educational Research     Open Access   (Followers: 76)
American Journal of Health Education     Hybrid Journal   (Followers: 39)
American Journal of Physics     Full-text available via subscription   (Followers: 58)
American String Teacher     Full-text available via subscription   (Followers: 3)
Ana Dili Eğitimi Dergisi / Journal of Mother Tongue Education     Open Access   (Followers: 1)
ANALES de la Universidad Central del Ecuador     Open Access   (Followers: 4)
Anargya : Jurnal Ilmiah Pendidikan Matematika     Open Access   (Followers: 8)
Annales Universitatis Mariae Curie-Sklodowska, sectio N – Educatio Nova     Open Access  
Annali dell'Universita di Ferrara     Hybrid Journal  
Annals of Dyslexia     Hybrid Journal   (Followers: 11)
Annals of Modern Education     Full-text available via subscription   (Followers: 6)
Antistasis : An Open Educational Journal     Open Access   (Followers: 9)
Anuario Pilquen : Sección Divulgación Científica     Open Access  
Apertura. Revista de innovación educativa‏     Open Access   (Followers: 3)
Ápice : Revista de Educación Científica     Open Access  
Applied Environmental Education & Communication     Hybrid Journal   (Followers: 19)
Applied Measurement in Education     Hybrid Journal   (Followers: 11)
Aprender     Open Access  
AR-RIAYAH : Jurnal Pendidikan Dasar     Open Access  
Arabia     Open Access   (Followers: 1)
Arabiyatuna : Jurnal Bahasa Arab     Open Access   (Followers: 1)
Archivos de Ciencias de la Educación     Open Access   (Followers: 2)
Areté, Revista Digital del Doctorado en Educación de la Universidad Central de Venezuela     Open Access   (Followers: 1)
Arrancada     Open Access  
Ars Educandi     Open Access  
Art Design & Communication in Higher Education     Hybrid Journal   (Followers: 30)
Art Education     Hybrid Journal  
Arte e Investigación     Open Access   (Followers: 1)
Arts and Humanities in Higher Education     Hybrid Journal   (Followers: 49)
Arts Education Policy Review     Hybrid Journal   (Followers: 6)
Artseduca : Revista electrónica de educación en las ARTES     Open Access   (Followers: 1)
ASHE Higher Education Reports     Hybrid Journal   (Followers: 21)
Asia Pacific Education Review     Hybrid Journal   (Followers: 13)
Asia Pacific Journal of Education     Hybrid Journal   (Followers: 27)
Asia-Pacific Education Researcher     Hybrid Journal   (Followers: 16)
Asia-Pacific Journal of Teacher Education     Hybrid Journal   (Followers: 28)
Asia-Pacific Science Education     Open Access   (Followers: 1)
Asian Association of Open Universities Journal     Open Access   (Followers: 1)
Asian Education and Development Studies     Hybrid Journal   (Followers: 7)
Asian Journal of Distance Education     Open Access   (Followers: 5)
Asian Journal of Education and Social Studies     Open Access   (Followers: 3)
Asian Journal of English Language Teaching     Full-text available via subscription   (Followers: 19)
Asian Journal of Legal Education     Full-text available via subscription   (Followers: 4)
Asian-Pacific Journal of Second and Foreign Language Education     Open Access   (Followers: 6)
ASp     Open Access   (Followers: 4)
Assessing Writing     Hybrid Journal   (Followers: 17)
Assessment & Evaluation in Higher Education     Hybrid Journal   (Followers: 259)
Assessment for Effective Intervention     Hybrid Journal   (Followers: 15)
Assessment in Education: Principles, Policy & Practice     Hybrid Journal   (Followers: 50)
Assessment Update     Hybrid Journal   (Followers: 7)
AStA Wirtschafts- und Sozialstatistisches Archiv     Hybrid Journal   (Followers: 5)
At-Ta'dib Jurnal Kependidikan Islam     Open Access  
At-Taqaddum     Open Access  
At-Turats     Open Access  
ATENA Didaktik     Open Access   (Followers: 5)
Atenas : Revista Científico Pedagógica     Open Access   (Followers: 1)
Athenea Digital     Open Access  
ATIKAN : Jurnal Kajian Pendidikan (Journal of Educational Studies)     Open Access  
Atthulab : Islamic Religion Teaching and Learning Journal     Open Access   (Followers: 1)
Aula Abierta     Open Access   (Followers: 2)
Aula de Encuentro     Open Access  
Australasian Journal of Educational Technology     Open Access   (Followers: 20)
Australasian Journal of Engineering Education     Hybrid Journal   (Followers: 3)
Australasian Journal of Gifted Education     Full-text available via subscription   (Followers: 8)
Australasian Marketing Journal (AMJ)     Hybrid Journal   (Followers: 6)
Australian Art Education     Full-text available via subscription   (Followers: 8)
Australian Educational Researcher     Hybrid Journal   (Followers: 34)
Australian Journal of Adult Learning     Full-text available via subscription   (Followers: 16)
Australian Journal of Career Development     Hybrid Journal   (Followers: 5)
Australian Journal of Dyslexia and Other Learning Difficulties     Full-text available via subscription   (Followers: 10)
Australian Journal of Education     Hybrid Journal   (Followers: 51)
Australian Journal of Environmental Education     Full-text available via subscription   (Followers: 11)
Australian Journal of Indigenous Education, The     Full-text available via subscription   (Followers: 15)
Australian Journal of Learning Difficulties     Hybrid Journal   (Followers: 7)
Australian Journal of Music Education     Full-text available via subscription   (Followers: 6)
Australian Journal of Public Administration     Hybrid Journal   (Followers: 473)
Australian Journal of Teacher Education     Open Access   (Followers: 31)
Australian Mathematics Teacher, The     Full-text available via subscription   (Followers: 7)
Australian Primary Mathematics Classroom     Full-text available via subscription   (Followers: 7)
Australian Screen Education     Full-text available via subscription   (Followers: 3)
Australian TAFE Teacher     Full-text available via subscription   (Followers: 4)
Australian Universities' Review, The     Full-text available via subscription   (Followers: 4)
Autism     Hybrid Journal   (Followers: 359)
Avaliação : Revista da Avaliação da Educação Superior (Campinas)     Open Access  
Azalea: Journal of Korean Literature & Culture     Full-text available via subscription   (Followers: 4)
Bahastra     Open Access  
Balkan Region Conference on Engineering and Business Education     Open Access   (Followers: 2)
Baltic Journal of Career Education and Management     Open Access   (Followers: 1)
Barn : Forskning om barn og barndom i Norden     Open Access   (Followers: 1)
Basastra : Jurnal Bahasa, Sastra, dan Pengajarannya     Open Access   (Followers: 1)
BC TEAL Journal     Open Access  
Becoming : Journal of the Georgia Middle School Association     Open Access   (Followers: 3)
Behavioural Sciences Undergraduate Journal     Open Access   (Followers: 6)
BELAJEA : Jurnal Pendidikan Islam     Open Access  
BELIA : Early Childhood Education Papers     Open Access   (Followers: 10)
BELT - Brazilian English Language Teaching Journal     Open Access   (Followers: 5)
Berkeley Review of Education     Open Access   (Followers: 10)
Beyond Behavior     Hybrid Journal   (Followers: 2)
Biblioteca Escolar em Revista     Open Access  
Biblioteka i Edukacja     Open Access   (Followers: 4)
Bio-Lectura     Open Access  
BIODIK : Jurnal Ilmiah Pendidikan Biologi     Open Access   (Followers: 1)
Bioedukasi : Jurnal Pendidikan Biologi FKIP UM Metro     Open Access   (Followers: 1)
Bioeduscience     Open Access   (Followers: 3)
Bioma : Jurnal Ilmiah Biologi     Open Access  
Biomedical Engineering Education     Hybrid Journal   (Followers: 2)
Biosaintifika : Journal of Biology & Biology Education     Open Access   (Followers: 9)
Biosfer : Jurnal Biologi dan Pendidikan Biologi     Open Access  
Biosfer : Jurnal Tadris Biologi     Open Access  
BISE : Jurnal Pendidikan Bisnis dan Ekonomi     Open Access   (Followers: 1)
Biuletyn Historii Wychowania     Open Access  
BMC Medical Education     Open Access   (Followers: 50)
BMJ Simulation & Technology Enhanced Learning     Hybrid Journal   (Followers: 13)
Boletim Cearense de Educação e História da Matemática     Open Access  
Boletim de Educação Matemática     Open Access  
Boletim Técnico do Senac     Open Access  
Bordón : Revista de Pedagogía     Open Access   (Followers: 1)
British (Jurnal Bahasa dan Sastra Inggris)     Open Access   (Followers: 1)
British Educational Research Journal     Hybrid Journal   (Followers: 281)
British Journal of Educational Studies     Hybrid Journal   (Followers: 212)
British Journal of Educational Technology     Hybrid Journal   (Followers: 211)
British Journal of Music Education     Hybrid Journal   (Followers: 28)
British Journal of Religious Education     Hybrid Journal   (Followers: 11)
British Journal of Sociology of Education     Hybrid Journal   (Followers: 66)
British Journal of Special Education     Hybrid Journal   (Followers: 60)
British Journal of Visual Impairment     Hybrid Journal   (Followers: 14)

        1 2 3 4 5 6 7 8 | Last

Similar Journals
Journal Cover
Biosaintifika : Journal of Biology & Biology Education
Number of Followers: 9  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2085-191X - ISSN (Online) 2338-7610
Published by Universitas Negeri Semarang Homepage  [77 journals]
  • The Mitotic Index of Cajanus cajan from Kisar Island, in the Southwest of
           Maluku

    • Authors: Kristin Sangur, Alwi Smith, Meike Tomasoa
      Pages: 128 - 134
      Abstract: The mitotic index of the roots of pigeon pea can be the basis for determining the growth of pigeon pea. The purpose of this research was to determine the time of root cell division, to observe the mitotic phases, and to determine the mitotic index of pigeon pea root cells. The preparation of the pigeon pea was carried out for 4 days to grow the roots. The roots were cut off at 08.00, 08.15, and 08.30 WIT (Eastern Indonesian Time). The roots were cut 0.5-1cm. Carnoy’s solution was used as the fixative solution using the Squash technique. The prepared roots were then observed using an Olympus cx-22 microscope and an OptiLab camera with a magnification of 100x40. The data were descriptively analyzed to describe the images of mitotic phases and the mitotic index presentation in the root cells of pigeon pea. The results of this research showed that the cell division of the pigeon pea roots began at 08.00 WIT, which was marked by the presence of a lot of prophase. The next phases that appeared were prometaphase, metaphase, and anaphase which occurred from 08.15 to 08.30 with different numbers. The highest mitotic index occurred at 08.15, when most of the root cells underwent metaphase. This study succeeded in revealing that the optimum time for pigeon pea root cell division is 08.15 WIT. In the future, this research can help pigeon pea farmers in Southwest of Maluku to carry out vegetative reproduction which is closely related to this mitotic study.
      PubDate: 2021-08-24
      DOI: 10.15294/biosaintifika.v13i2.29496
      Issue No: Vol. 13, No. 2 (2021)
       
  • The Histomorphometry of Liver and Kidney of Hyperglycemic Albino Rats
           after Treatment with Tithonia diversifolia Leaf Extract

    • Authors: Rizki Fitrawan Yuneldi, Tyas Rini Saraswati, Enny Yusuf Wachidah Yuniwarti
      Pages: 135 - 141
      Abstract: Tithonia diversifolia can be used as an antidiabetic, so it is necessary to study the safety of its use, especially the side effects on the liver and kidneys. This study aimed to determine the effect of using T. diversifolia leaf extract through histomorphometry observations of the liver and kidneys of hyperglycemic albino rats. The study design used a completely randomized design (CRD). This study used 20 male albino rats which were divided into five treatment groups, there were T0 (rat normal/control), T1 (hyperglycemic rat without T. diversifolia leaf extract), T2 (hyperglycemic rat administered with Glibenclamide 10 mg/kg BW), T3 (hyperglycemic rat administered with T. diversifolia leaf extract 150 mg/kg BW), T4 (hyperglycemic rat administered with T. diversifolia leaf extract 300 mg/kg BW). Every treatment was repeated four times. The damage of hepatocyte and the glomerular cell was observed through histological structure observation by histomorphometry method using a photomicrography microscope (Olympus BX51). The results indicate that there were significant differences (P < 0.05) in the variable of hepatocytes diameter and there was no significant different (P > 0.05) result on glomerular diameter, as well as kidney and liver weight. It was concluded that T. diversifolia leaf extract of 150 mg/kg BW and 300 mg/kg BW are safe to be used as antidiabetic. It does not cause any side effects on the liver and kidneys of hyperglycemic albino rats. Thereby T. diversifolia leaf extract can be further tested as preparation of biopharmaca which can be used as herbal medicines for diabetics.
      PubDate: 2021-08-25
      DOI: 10.15294/biosaintifika.v13i2.29459
      Issue No: Vol. 13, No. 2 (2021)
       
  • Blood-Glucose Levels of Rats Given High-Fat Diets after Administration of
           Neem Leaf Ethanolic Extract

    • Authors: Sri Isdadiyanto, Siti Muflichatun Mardiati, Agung Janika Sitasiwi
      Pages: 142 - 148
      Abstract: Azadirachta indica A. Juss (Neem) is a medicinal plant that contains antioxidants, antihyperlipidemia, and has antidiabetic activity. This research aimed to examine the effect of neem leaf ethanolic extract on blood glucose levels of white rats given high-fat rations. The male white rats (Rattus norvegicus L.) with two months of age were used. The treatment of test animals consisted of six treatment groups and four replications, namely: the control group (P0); given high fat rations + duck egg yolk 2.5 ml/200gBW (P1); given high-fat rations + 8 mg/200gBW simvastatin (P2); and P1+ the dose of neem leaf ethanolic extract of 75; 100; and 125 mg/200gBW (P3; P4; and P5). Blood-glucose levels were analyzed by colorimetric enzymatic method using Roche Diagnostics Cobas C reagents kits. Blood-glucose level was determined using Roche / Hitachi cobas c systems automatically. Homogeneous and normally distributed data of blood-glucose levels, body weight and feed consumption were analyzed statistically using ANOVA followed by Duncan's test with a significance level of 5% using SPSS 16.0 software. The results indicated that giving the neem leaf ethanolic extract of could reduce the blood glucose levels. In this study, it was concluded that the neem leaf ethanolic extract of could potentially be used as an alternative to cure diabetes mellitus.
      PubDate: 2021-08-25
      DOI: 10.15294/biosaintifika.v13i2.29516
      Issue No: Vol. 13, No. 2 (2021)
       
  • Conservation Status of Agarwood-Producing Species (Gyrinops versteegii) in
           Indonesia

    • Authors: Sutomo Sutomo, Rajif Iryadi, I Made Sumerta
      Pages: 149 - 157
      Abstract: Aquilaria malaccensis and Gyrinops versteegii are agarwood producing plant species that is widely used because of its fragrance. Gyrinops versteegii has not been much cultivated and along with the decreasing population of G. versteegii in its natural habitat. This study aimed to assess scarcity status of Gyrinops versteegii based on distribution records from both herbarium and field exploration to assist the formulation of its conservation policy. Distribution data were obtained from online database and also from field exploration in Lombok, Sumbawa, and Flores Islands to obtain the population information. Area of Occupancy (AOO) and Extent of Occurrence (EOO) were calculated using GeoCAT (Geospatial Conservation Assessment Tool) and IUCN status recommendation was discussed. The estimated EOO was 868,422,919 km2, exceeding the value required for the threatened category. Based on EOO, it is included in the Least Concern (LC) category, but the EOO covers a large area of the ocean so the AOO was 116 km2 as meets criterion B (AOO<500 km2). It can be categorized into endangered (EN). Population data and conservation status of G verstegii are very important to provide recommendations on the quota wild-harvesting of agarwood by stakeholders.
      PubDate: 2021-08-27
      DOI: 10.15294/biosaintifika.v13i2.27809
      Issue No: Vol. 13, No. 2 (2021)
       
  • Diversity of Pathogenic Fungi and Disease on Vegetable Crops at
           Polyculture Systems

    • Authors: Eddy Tri Sucianto, Muachiroh Abbas
      Pages: 158 - 168
      Abstract: Vegetables polyculture system is potentially increasing pathogenic fungi diversity because various plant hosts are available. There is no data about patogenic fungi diversity at polyculture vegetable farming in Serang village, District of Karangreja, Purbalingga Regency. This study aimed to determine patogenic fungal diversity and disease percentage caused by the fungi at polyculture vegetable farming in Serang village, District of Karangreja, Purbalingga Regency. This research used purposive random sampling. Infected plants were collected at ten polyculture farming locations and fungal identification was performed at the laboratory. Fungi were identified morphologically based on the signs, symptoms, as well as macroscopic and microscopic characters. The fungi's pathogenity was determined by applying Koch's postulate test. The data were analyzed descriptively through literature comparison. The results showed that seven fungal species were found at polyculture farms in Serang Village. The obtained fungi were Colletotrichum sp., Fusarium sp., Alternaria sp., Septoria sp., Cercospora sp., Botryodiplodia sp., and Nigrospora sp. The lowest damage was 18.24% on tomato fruit infected by Fusarium sp. and the highest was on chili plants which was caused by Colletotrichum sp. The data is the first report for polycuture system. The obtained data has important implication for the management of vegetables farming in Serang Village.
      PubDate: 2021-08-27
      DOI: 10.15294/biosaintifika.v13i2.26987
      Issue No: Vol. 13, No. 2 (2021)
       
  • Effects of Light Environments on Leaf Traits and Phenotypic Plasticity of
           Canna indica

    • Authors: Yorianta Hidayat Sasaerila, Sakinah Sakinah, Nita Noriko, Risa Swandari Wijihastuti
      Pages: 169 - 177
      Abstract: Canna indica L (African arrowroot), is a beneficial, multi-use tropical perennial with a worldwide distribution, but relatively unexplored. This plant has the potential to be developed as a food crop in an intercropping system, utilizing idle land under commercial plantations such as rubber or teak. This study aimed to determine the best light-growing conditions for C. indica. A completely randomized design was used with growth light as the treatment consisting of 25%, 50%, and 100% of natural light, respectively. Leaf traits, growth characteristics, and phenotypic plasticity were used to measure C. indica’s response to different treatments. The results of this study showed that C. indica grown in low light has the best growth with increased height, leaf area, root and shoot dry weights, but decreased leaf thickness, which caused the increase in specific leaf area, leaf area ratio, and leaf weight ratio, but decreased root to shoot ratio. Based on leaf traits and biomass allocation, the phenotypic plasticity index was 0.23, a typical number for shade tolerant species. These findings were the first time to be reported for C. indica. For agroforestry practices, it can be recommended that C. indica be used as an intercropping plant under tree canopies.
      PubDate: 2021-08-27
      DOI: 10.15294/biosaintifika.v13i2.30175
      Issue No: Vol. 13, No. 2 (2021)
       
  • Pancreatic Lipase Inhibitory Activity of Endophytic Actinobacteria from
           Rhododendron spp.

    • Authors: Witri Winanda, Irmanida Batubara, Yulin Lestari
      Pages: 178 - 184
      Abstract: Antiobesity medication is available as therapeutic compounds that can reduce fat digestion by the inhibition of pancreatic lipase. Actinobacteria have the potency as source of bioactive compounds with various biological function including as pancreatic lipase inhibitor.  However, the potency of endophytic actinobacteria from Rhododendron spp. as source of pancreatic lipase inhibitor producer has not been reported yet. The aim of this study was to examine the potential of pancreatic lipase inhibitory activity of 23 endophytic actinobacteria from Rhododendron spp.; to characterize their colony based on morphology and molecular analysis. Screening test of pancreatic lipase inhibitor was conducted using the supernatant of endophytic actinobacteria, lipase pancreatic porcine (L3126) and p-nitrophenyl butyrate. The supernatant of selected isolates was extracted using ethyl acetate. The result showed that various inhibitory activities ranging between 0.00 until 91.69%. There were 11 out of 23 isolates that have potential as pancreatic inhibitor. Amongst them, the extract of four selected isolates, i.e. RZP 1.3, RSSB 3.2, RSS 2.1, and RJB F3.2 demonstrated inhibitory percentage of more than 80%. The RJB F3.2 extract showed to have IC50 value by 431.48 µg mL-1 compared to control, i.e. Xenical (89.07 µg mL-1). Phytochemical analysis exhibited that the extract of the selected isolates contained alkaloid which may function as pancreatic lipase inhibitor. Based on the morphological character, the selected isolates have various morphological colonies and 16S rRNA gene sequence revealed the sequence homology to Streptomyces spp. The data clearly indicate that endophytic actinobacteria from Rhododendron spp. have potency as pancreatic lipase inhibitor producer and further studies could be explored for the development of antiobesity agent.
      PubDate: 2021-08-30
      DOI: 10.15294/biosaintifika.v13i2.29981
      Issue No: Vol. 13, No. 2 (2021)
       
  • Antidiabetic Potential of Methanol Extract of Flamboyant (Delonix regia)
           Flowers

    • Authors: Kartini Eriani, Uswatun Hasanah, Rizky Fitriana, Widya Sari, Yunita Yunita, Al Azhar
      Pages: 185 - 194
      Abstract: Providing scientific evidences for the medicinal benefits and possible toxic effects of the flamboyant flowers (Delonix regia (Bojer ex Hook.) Raf.) are very important to implementing the medicinal plant in this modern era. This study aimed to investigate antidiabetic potential of methanol extract of flamboyant flowers using a completely random design. Twenty-four male rats were randomly divided into 6 treatment groups with 4 replications: healthy rats (normal control, P1), diabetic rats treated with flamboyant flower extract of 0 (negative control, P2), 100 (P3), 200 (P4), and 400 mg/kg BW (P5), and rats which were induced by 0.45 mg/kg BW of Glibenclamide (positive control, P6). Diabetic condition was achieved by a single injection of alloxan 150 mg/kg BW. Treatments were given once a day for 14 days. On day 0, 3 and 18 blood samples were withdrawn from rats’ orbital vein for glucose measurement. All rats were sacrificed for liver, gastrocnemius muscles and pancreatic tissues collection. The liver and gastrocnemius muscle were subjected for glycogen measurement whereas pancreatic tissues were processed for histological examinations. Data was analyzed by ANOVA and followed by Duncan test. The results showed that flamboyant flowers extracts significantly (p<0.05) reduced blood glucose as well as degeneration and necrosis of pancreatic β cells. Optimal dose to decrease blood glucose and pancreatic cell degeneration was 200 mg/kg BW; whereas optimum dose to decrease pancreatic cell necrosis was 400 mg/kg BW. In conclusion, flamboyant flower extract can reduce blood glucose in rats. This is the first that shows antidiabetic potential of local Flamboyant flower extracts along its toxicity effect to pancreatic tissues. These information could become a basic consideration for the use of the plant extracts as a candidate to cure patients with diabetic problems.
      PubDate: 2021-08-30
      DOI: 10.15294/biosaintifika.v13i2.30080
      Issue No: Vol. 13, No. 2 (2021)
       
  • Morphological Characterization and Physical Dormancy of Bauhinia winitii
           Seed: Living Collection of Purwodadi Botanic Garden

    • Authors: Dewi Ayu Lestari, Elok Rifqi Firdiana
      Pages: 195 - 200
      Abstract: Bauhinia winitii Craib (Fabaceae, Caesalpinioideae) is a woody climber which is currently included in endangered species list. B. winitii seeds are orthodox seeds in which it has hard coat morphologically. Therefore, B. winitii seeds often undergo physical dormancy which can be broken through immersion in certain liquid media. This study aimed to characterize the morphology of B. winitii seeds and determine the pre-sowing treatment method to accelerate the seeds germination of B. winitii. External morphological characterization was carried out by observing the seeds quantitative and qualitative parameters. Characterization of seeds internal morphology was conducted using a digital microscope. Physical dormancy breaking was carried out by immersion in warm and cold water for 24 hours. Morphological characterization data were analyzed descriptively, while seed germination data were analyzed quantitatively by using one-way ANOVA followed by LSD test (with  confidence level of 95%). B. winitii has pod-shaped fruits with 2-6 seeds per pod, the seeds are 1.36 cm x 1 cm in size, 0.47 cm thick and weighed 0.5 g, oblong to conical in shape, smooth and shine surface, with light to dark brown in color. Seeds immersion treatment in warm water could break the physical dormancy of B. winitii seeds thus 63% of the seeds were able to germinate and it was significantly different compared to control and cold water immersion treatment. Technical to germinate B. winitii seed can be known from pre-sowing treatment. This study can be used as a reference for seed identification and germination technical of B. winitii seed.
      PubDate: 2021-08-02
      DOI: 10.15294/biosaintifika.v13i2.30501
      Issue No: Vol. 13, No. 2 (2021)
       
  • The Combination of Phyllanthus niruri, Euphorbia hirta, and Loranthus sp.
           as a Source of Antioxidant Agents

    • Authors: Elizabeth Betty Elok Kristiani, Sri Kasmiyati
      Pages: 201 - 211
      Abstract: Meniran (Phyllanthus niruri), patikan kebo (Euphorbia hirta), and benalu (Loranthus sp.) have often been used by people as medicinal plants. This research aimed to measure the levels of flavonoids, phenolics, and ascorbic acid compounds, as well as the Free Radical Scavenging (FRS) activity of ethyl acetate extract from the mixture of P. niruri, E. hirta, and Loranthus sp. The FRS activity was measured with the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The level of compounds was measured by using the spectrophotometry method with specific reagents. The result of the FRS activity in ethyl acetate extract from the mixture of P. niruri, E. hirta, and Loranthus sp. varied depending on its dose. The measure of FRS in the P. niruri: E. hirta: Loranthus sp 0:0:1 (K-OOL) composition showed a strong result with a value of IC50 97.2 ± 2.1 ppm, while in the 0:0.5:0.5 (K-OEL) composition it was moderate with a value of IC50 147.6 ± 6.5 ppm. The other compositions showed weak and inactive results. The K-OOL composition had the highest flavonoid and phenolic content that were 298.8±0.00 mg QE/g extract and 141.5±2.85 mg GAE/g extract respectively. The composition with the highest ascorbic acid content (298.8±0.00 mg/g extract) was K-OEO composition. So far, research on medicinal plants is still limited to one type of plant. The combination of several types of plants in several formulations allows obtaining a composition that can produce maximum antioxidant capacity. Therefore, this research is expected to produce a combination formulation of various types of medicinal plants that have the K-OOL composition very strong antioxidant activity and can be used as herbal medicines.
      PubDate: 2021-08-09
      DOI: 10.15294/biosaintifika.v13i2.30718
      Issue No: Vol. 13, No. 2 (2021)
       
  • Genetic Diversity and Relationships of Phalaenopsis Based on the rbcL and
           trnL-F Markers: In Silico Approach

    • Authors: Dindin Hidayatul Mursyidin, Gusti Muhammad Zainal Ahyar, Ahmad Winarto Saputra, Aminoor Hidayat
      Pages: 212 - 221
      Abstract: In silico is the more comprehensive and applicable approach in supporting, both conservation and breeding programs of germplasm. The study aimed to analyze and determine the genetic diversity and relationships of 24 species of Phalaenopsis using two DNA barcoding markers, namely the rbcL and trnL-F, by in silico approach. All sequences of these markers were collected randomly from the NCBI website and analyzed using several softwares and methods, such as ClustalW and MultAlin for multiple sequence alignments and MEGA-X to determine its genetic diversity and relationships. Specifically, the genetic diversity was determined using a nucleotide diversity index and their relationships by the Maximum Likelihood method. The results showed that Phalaenopsis has a low genetic diversity of 0.24, 0.32, and 0.19, respectively. The phylogenetic analysis revealed that this orchid separated into five (for the rbcL), six (trnL-F), and seven clades (a combined one), where the closest relationship is shown by P. amboinensis vs. P. venosa, whereas the farthest by P. gibbosa vs. P. doweryensis, P. stuartiana vs. P. micholitzii, and P. celebensis vs. P. pulchra. The results have novel information on the diversity and relationships of Phalaenopsis on the in silico approach. Thus, our findings might be used in supporting the conservation and breeding program of Phalaenopsis, both locally and globally.
      PubDate: 2021-08-09
      DOI: 10.15294/biosaintifika.v13i2.29904
      Issue No: Vol. 13, No. 2 (2021)
       
  • Study of the Germination of Six Begonia Species as an Effort to Preserve
           Genetic Resources

    • Authors: Cokorda Istri Meyga Semarayani, Ayyu Rahayu
      Pages: 222 - 229
      Abstract: Begonia is an ornamental plant that has a high level of morphological diversity. Begonia propagation is mostly done vegetatively and very rarely to propagate sexually. Therefore, this study was conducted to determine the ability of six types of Begonia seeds to germinate. Six types of Begonia, namely B. x albopicta W. Bull 'Coral Rubra', B. gambutensis Ardi & D.C.Thomas, B. multistaminea Burt-Utley, B. nelumbifolia Schltdl. & Cham., B. ulmifolia Wild. and B. varipeltata D.C.Thomas. were grown in a petri dish and placed in a growth chamber with a temperature of 23.6 ℃, humidity of 74.5%, and a light intensity of 3,431 lux. The results showed that the different types of Begonia showed significant differences in all the parameters tested. B. nelumbifolia required 7.89 ± 0.18 days to germinate and is the fastest time than other types. The highest percentage of seed germination was also obtained by this species, amounting to 63.22%. In addition, B. nelumbifolia showed the best response to the germination rate coefficient, germination rate index, and germination index. This study revealed complete information about the germination of six types of Begonia. In addition, the ability to produced many seeds and the ease of germination made this plant have the potential to be cultivated through seeds. Furthermore, the information can be used as a basis for seed storage as an ex-situ conservation method to maintain genetic diversity.
      PubDate: 2021-08-12
      DOI: 10.15294/biosaintifika.v13i2.30255
      Issue No: Vol. 13, No. 2 (2021)
       
  • Potential of Calliandra calothyrsus Leaf Extract to Maintain Estrogen
           Concentration and Uterine Thickness in Rats

    • Authors: Iriani Setyawati, Ni Nyoman Wirasiti, Luh Putu Eswaryanti Kusuma Yuni
      Pages: 230 - 236
      Abstract: Calliandra calothyrsus Meissn. leaf extract is potential as phytoestrogens. It influenced male mice reproduction, rat estrous cycle, and ovarian histology in previous study. This research aimed to prove the C. calothyrsus leaf extract potential as phytoestrogen source and the effect on endometrial thickness where the embryo implantation take place in early pregnancy. This study used a Completely Randomized Design used 54 days old female rats (Rattus norvegicus). Rats were divided into K as control group (treated with 0.5% Na-CMC as placebo) and P1, P2, and P3 as three groups with C. calothyrsus leaf extract administration with doses of 17.5; 35; and 70 mg/ kg bw respectively. Treatments were given 1 ml/rat/day orally for 20 days. At day 21st, animals were euthanized to collect blood samples for estrogen hormone analysis. After the dissection, all uterus were collected and weighed. Histological preparation was done with paraffin method and Hematoxylin-Eosin staining. The effective dose was 70 mg/ kg bw that did not decrease the weight of the uterus and the body. This dose even maintained the normal diameter and thickness of uterine walls (endometrium, myometrium, and perimetrium layers) like control rats. The extract in this study could increase estrogen concentration in female rats. This research novelty is that C. calothyrsus leaf extract (70 mg/ kg bw) can be used as an alternative herbal suplement to maintain uterine wall thickness and estrogen concentration in productive women. With further clinical research, this extract is a good candidate as potential estrogen source to overcome women infertility or pregnancy difficulties due to problem of endometrial thickness and lack of endogenous estrogen.
      PubDate: 2021-08-15
      DOI: 10.15294/biosaintifika.v13i2.31063
      Issue No: Vol. 13, No. 2 (2021)
       
  • The Density and Viability of Metarhizium anisopliae Conidia on Several
           Growth Media

    • Authors: Dyah Rini Indriyanti, Siti Harnina Bintari, Ning Setiati, Jamil Maulana Zahriyan Alfiyan
      Pages: 237 - 242
      Abstract: Metarhizium anisopliae is a parasitic fungus on insects, and thus called entomopathogenic fungus. This fungus is used as a biological control agent for insect pests. Fungal propagation can be done using a variety of media. The purpose of this study was to analyze the growth of M. anisopliae on four types of media, with conidial density and viability as the growth parameters. This research was conducted at the Laboratory of Microbiology, Universitas Negeri Semarang. This study was an experimental research used a Completely Randomized Design (CRD) with one factor and four treatments: Control (PDA/Potato Dextrose Agar medium), Treatment I (ELSA/Extract Larvae Sucrose Agar medium), Treatment II (CWSA/Coconut Water Sucrose Agar medium), Treatment III (CWELSA/Coconut Water and Extract Larvae Sucrose Agar medium). The and results showed that there was an effect of growth media on the density and viability of M. anisopliae conidia. CWELSA media had the highest conidial density (2.91 x 108 cfu/mL) and viability (97.17%). CWSA media had  2.82 x 108 cfu/mL and 95.33%. PDA media had 2.25 x 108 cfu/mL and 92.83%. ELSA media had 1.64 x 108 cfu/mL and 90.83%. The high conidial density and viability of M. anisopliae is CWELSA  medium. This study is as an alternative growth medium to improve the quality of M. anisopliae propagation.
      PubDate: 2021-08-02
      DOI: 10.15294/biosaintifika.v13i2.31408
      Issue No: Vol. 13, No. 2 (2021)
       
  • The Influence of Inducers on the Coltricia cinnamomea Laccase Activity and
           its Ability to Degrade POME

    • Authors: Yohanes Bernard Subowo, Arwan Sugiharto
      Pages: 243 - 249
      Abstract: Some species of Basidiomycetes, specifically white rot groups, produce three ligninolytic enzymes, namely, Lignin Peroxidase (LiP), Manganese Peroxidase (MnP) and Laccase (Lac), which have low activity in degrading Palm Oil Mill Effluent (POME). The research objective was to obtain the data on the ability of the Coltricia cinnamomea to produce LiP, MnP, and Lac enzymes to degrade POME. This research also studied the effect of sucrose, alcohol, veratryl alcohol, CuSO4 and ZnSO4,as inducers. Isolates of Coltricia cinnamomea, which were stored in a PDA media at -20℃ were obtained from the Microbiology section of the Research Center for Biology (LIPI). Furthermore, the growth media used were DM, Bean sprout Extract (TE) and PDB. The result indicated that PDB is the most suitable growth media for the production of ligninolytic enzymes, because in this medium these enzymes showed the highest activity. It was also observed that sucrose increased the laccase activity by 40.80%. Furthermore, Coltricia cinnamomea was able to reduce the concentration of Poly R-478 by 60.74%, after the addition of ZnSO4. In addition, it degraded and decreased the color and COD of POME, by 72.63% and 91.19% respectively, after the addition of veratryl alcohol, and incubation for 10 days. Therefore, this fungus can be used to degrade POME in order to prevent environmental pollution. Coltricia cinnamomea has not been used for POME degradation. By using Coltricia cinnamomea, we  obtained new data regarding the activity of laccase and its ability to degrade POME. 
      PubDate: 2021-08-06
      DOI: 10.15294/biosaintifika.v13i2.29660
      Issue No: Vol. 13, No. 2 (2021)
       
  • Analysis of The Morphological Characteristics of Bush Frog Philautus spp.
           Gistel, 1848 (Anura: Rhacophoridae) from Mount Ungaran

    • Authors: Margareta Rahayuningsih, Winda Rahmawati, Amir Hamidy
      Pages: 250 - 257
      Abstract: Traditionally, the genus Philautus Gistel, 1848 contains small Rhacoporid frogs that lack vomerine teeth and a direct development tadpole stage. In Java, this genus consists of 3 species, including Philautus aurifasciatus, Philautus jacobsoni, and Philautus pallidipes. It is known that Philautus aurifasciatus and Philautus jacobsoni are sympatric species from Mount Ungaran and are morphologically difficult to distinguish. Therefore, information is needed through the phenetic characters of each population in the area to identify differences in their morphology. This study aimed to analyze the morphological characteristics of  Bush Frog Philautus spp. on Mount Ungaran in terms of meristic character through a direct field survey and comparison methods. Furthermore, it was conducted by observing 32 specimens of Philautus spp. from Mount Ungaran and compared with the Philautus aurifasciatus from Mount Gede Pangrango with 18 meristic characters. The results showed that Philautus spp. is similar to Philautus aurifasciatus in terms of their meristic characters. The results of the meristic analysis showed that Philautus spp. has a variety of dorsal colors from brown, purple, green, and gray with two types of patterns including patterned groups (resembling letters H, X, and V) and abstract. Furthermore, the throat, stomach, and lower thighs are granular with three snout shapes (protruding, round, and sloping). It has a loreal oblique tympanum and canthus rostralis. The forelimbs are not webbed while the hindlimbs are half webbed, and the inner metatarsal is an elongated oval in shape. Meristic analysis provides a basis for strengthening the taxonomic status of Philautus spp on Mount Ungaran, as well as information the distribution in Mount Ungaran.
      PubDate: 2021-08-06
      DOI: 10.15294/biosaintifika.v13i2.31298
      Issue No: Vol. 13, No. 2 (2021)
       
 
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