Subjects -> CHEMISTRY (Total: 986 journals)
    - ANALYTICAL CHEMISTRY (59 journals)
    - CHEMISTRY (713 journals)
    - CRYSTALLOGRAPHY (23 journals)
    - ELECTROCHEMISTRY (28 journals)
    - INORGANIC CHEMISTRY (45 journals)
    - ORGANIC CHEMISTRY (47 journals)
    - PHYSICAL CHEMISTRY (71 journals)

ORGANIC CHEMISTRY (47 journals)

Showing 1 - 41 of 41 Journals sorted alphabetically
ACS Omega     Open Access   (Followers: 2)
Advances in Image and Video Processing     Open Access   (Followers: 18)
Advances in Physical Organic Chemistry     Full-text available via subscription   (Followers: 4)
Advances in Redox Research     Open Access   (Followers: 4)
American Journal of Organic Chemistry     Open Access   (Followers: 15)
Asian Journal of Organic Chemistry     Hybrid Journal   (Followers: 4)
Beilstein Journal of Organic Chemistry     Open Access   (Followers: 13)
Biochemia Medica     Open Access  
Current Organic Chemistry     Hybrid Journal   (Followers: 14)
Current Organic Synthesis     Hybrid Journal   (Followers: 12)
European Journal of Organic Chemistry     Hybrid Journal   (Followers: 59)
Herbal Medicine: Open Access     Open Access  
International Journal of Organic Chemistry     Open Access   (Followers: 9)
International Journal of Polymeric Materials     Hybrid Journal   (Followers: 6)
Journal of Bioactive and Compatible Polymers     Hybrid Journal   (Followers: 2)
Journal of Biomaterials Science, Polymer Edition     Hybrid Journal   (Followers: 9)
Journal of Organic Semiconductors     Open Access   (Followers: 6)
Journal of Peptide Science     Hybrid Journal   (Followers: 14)
Journal of Physical Organic Chemistry     Hybrid Journal   (Followers: 8)
Journal of Physiology and Biochemistry     Hybrid Journal   (Followers: 3)
Journal of Progressive Research in Chemistry     Open Access  
Journal of Proteins and Proteomics     Open Access   (Followers: 2)
Mini-Reviews in Organic Chemistry     Hybrid Journal   (Followers: 10)
Nigerian Journal of Chemical Research     Full-text available via subscription   (Followers: 1)
Open Journal of Organic Polymer Materials     Open Access   (Followers: 1)
Organic & Biomolecular Chemistry     Hybrid Journal   (Followers: 56)
Organic and Medicinal Chemistry Letters     Open Access   (Followers: 5)
Organic Chemistry : Current Research     Open Access   (Followers: 12)
Organic Chemistry Frontiers     Hybrid Journal   (Followers: 9)
Organic Chemistry International     Open Access   (Followers: 7)
Organic Geochemistry     Hybrid Journal   (Followers: 3)
Organic Letters     Hybrid Journal   (Followers: 92)
Organic Preparations and Procedures International: The New Journal for Organic Synthesis     Hybrid Journal   (Followers: 3)
Organic Process Research & Development     Hybrid Journal   (Followers: 32)
Progress in Organic Coatings     Hybrid Journal   (Followers: 7)
Reports in Organic Chemistry     Open Access   (Followers: 7)
Russian Journal of Organic Chemistry     Hybrid Journal   (Followers: 3)
Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry     Hybrid Journal   (Followers: 31)
The Journal of Organic Chemistry     Hybrid Journal   (Followers: 135)
Vibrational Spectroscopy     Hybrid Journal   (Followers: 11)
World Journal of Organic Chemistry     Open Access   (Followers: 5)
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Letters in Organic Chemistry
Number of Followers: 8  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 1570-1786 - ISSN (Online) 1875-6255
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  • A Convenient Stereoselective Method for Synthesis of β-Lactams Under
           Microwave Irradiation with [BmIm] OH as a Reusable Ionic Liquid

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      Abstract: A promoted synthetic protocol for the β-lactams synthesis in the presence of [BmIm]OH as a basic reagent under microwave irradiation [M.W.I.] is described. The reaction was highly diastereoselective. In all cases, this protocol provided trans-β-lactams as major isomers, and β-lactams were obtained with good yields. Further, the effect of the order of addition of the reagents was particularly investigated; we found that this order is very important. The best results are obtained when the imine is added gradually. This work shows that [BmIm]OH is an advantageous recyclable basic reagent. A qualitative molecular orbital diagram is illustrated to interpret the observed diastereoselectivity.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • Critical Review of Biotransformational Studies on Steroids by Using
           Culture of Cunninghamella blakesleeana

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      Abstract: For several decades, biotransformational studies on steroidal compounds have gained a lot of attention because it is an efficient approach for the structural modification of complicated natural or synthetic compounds with high regio-, chemo- and stereoselectivity at environmentally friendly conditions. This review summarizes the use of different strains of Cunninghamella blakesleeana for the biotransformation of sixteen steroids 1-16 into a variety of transformed products. The transformed products may be important as a drug or precursor for the production of important pharmaceuticals. The types of reactions performed by C. blakesleeana include hydroxylation, epoxidation, reduction, demethylation, oxidation, glycosidation, double bond formation, side-chain degradation, isomerisation and opening of an isoxazol ring, which would be difficult to produce by traditional synthesis.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • Sulfated Tin Oxide: A Convenient Heterogeneous Catalyst for the Synthesis
           of 4-Arylmethylidene-3-Substituted-Isoxazol-5(4H)-Ones

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      Abstract: Synthesis of isoxazole structural heterocyclic compounds is important due to their wide range of biological activities. In the present article, we report a convenient and easy method for the synthesis of 4-arylmethylidene-3-substituted-isoxazol-5(4H)-ones by the one-pot three-component reaction of aldehydes, β-keto ester, and hydroxylamine hydrochloride catalyzed by sulfated tin oxide as a heterogeneous catalyst.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • Synthesis and Biological Activity of Aldehyde Derivatives of Isopimaric
           Acid

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      Abstract: Four series of acylhydrazone derivatives, including halogenated aryl modified acylhydrazone, thiophene, pyrrole and quinoline, were synthesized and characterized. The minimum inhibitory concentrations of the compounds against five bacteria were determined and most of the compounds displayed some degree of antibacterial activity. Isopimaric acid (pyrrole-3-carboxaldehyde) acylhydrazone (3j) exhibited the most potent activity against Streptococcus pneumonia and Klebsiella Pneumonia, with the minimum inhibitory concentration being 3.91 μg/mL. The antimicrobial activity against S. pneumoniae was improved when the pyrrole structure was introduced into isopimaric acid. All heterocyclic acylhydrazone derivatives of isopimaric acid exhibited a good in vitro antitumorial activity at 100 μM. It is concluded that the inhibitory effect of isopimaric acid (2-fluoro-6-methoxybenzaldehyde) acylhydrazone (3d) on Hep G2 and isopimaric acid (3-bromothiophene-2-carbaldehyde) acylhydrazone (3g) on Hep G2 and MDAMB 231 is better than that of the positive control 5-fluorouracil (5-FU) (76.51%), which is a widely used clinical anticancer agent, at 100 μM.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • 2,5-Disubstituted-4-Thiazolidinones: Synthesis, Anti-Inflammatory, Free
           Radical Scavenging Potentials and Structural Insights through Molecular
           Docking

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      Abstract: The present work reports the synthesis and screening of fifteen 2,5-disubstituted-4- thiazolidinones with different substitutions at imino and varied arylidene groups. The structures of the compounds were confirmed by spectral characterization. The compounds were subjected to in vivo anti- inflammatory and in vitro antioxidant activities. The derivatives possessed remarkable activities quite close to standard drugs used. Unlike conventional non-selective NSAIDs, the synthesized compounds did not contain any acidic group thereby ensuring possible freedom from ulcers. To further substantiate the claim for safer derivatives, the active compounds were docked against cyclooxygenase (COX)-2 enzyme. It was found that 4-fluorophenylimino substituent at 2- position and 3-nitro moiety on 5-benzylidene nucleus of the 4-thiazolidinone derivative fitted in the COX-2 binding pocket. The compounds exhibited remarkable activity in scavenging free radicals as depicted by DPPH assay method. The structure-activity relationship was also established in the present work with respect to the nature and position of the substituents. The active compounds were evaluated for drug-like nature under Lipinski’s rule of five and the toxicity behavior of active compounds was predicted using ADMETlab software. The compounds have the potential to target degenerative disorders associated with inflammation and the generation of free radicals.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • Natural Crude Dye from Cucurbita Pepo Leaves for Dying, Antimicrobial, and
           Antioxidant Activities

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      Abstract: Owing to environmental concerns, a great attention is given to use plant waste for obtaining natural dyes. Cucurbita pepo (C. pepo) is one of the most abundantly grown seasonal vegetable plants in Pakistan. However, its leaves are of no use after crop season, and consequently, they are usually discarded. Hence, in this study an attempt is made to extract dye from C. pepo leaves for dying textiles and antimicrobial applications. The fractionation of the obtained dye was done by column chromatography while TLC, UV-Vis and FTIR analyses were performed to further evaluate the composition and nature of the obtained dye. The principal constituents of the obtained dye such as alkaloids, tannins, flavonoids, proteins and sugar were identified by chemical tests. The dye was successfully applied for dying of synthetic and cotton cloths which showed resistivity and high color fastness even after successive washings. Interestingly, the obtained dye changed color with change in temperature. For evaluating potential biomedical importance of the obtained dye, antibacterial and antioxidant activities were checked. Effective antioxidants as well as antimicrobial activity against E. coli were observed. From the present study, we concluded that the nature, composition, washing, and thermal stability, as well as the potential biomedical applicability of the obtained natural dye from C. Pepo leaves, can be a better option for commercialization in future.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • Ring Opening of 1,1’-Sulfonyl Bis-Aziridines Derived from L-Amino Acids
           and DFT Study of the Affinity Toward Different Nucleophiles

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      Abstract: We describe herein the ring-opening reaction of chiral 1,1’-sulfonyl bis-aziridines with various neutral and anionic nucleophiles including benzylamine, piperidine, acetate, allylthiolate, cyanide anion and sodium ethoxide. These reactions afforded bis-opened or/and mono-opened compounds via a regioselective attack on the non-substituted methylene of aziridine ring. The structures of the products were confirmed based on spectral analysis (IR, 1H NMR and 13C NMR). A theoretical study by density functional theory (DFT) was used to rationalize the region-selective ring-opening of starting bis-aziridines.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • Plant Extract-Assisted Green Synthesis of 2-Arylimidazo [1,2-A] Pyridine
           and Benzimidazole Derivatives

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      Abstract: A green and efficient method for the synthesis of 2-arylimidazo [1, 2-a] pyridine (3) and benzimidazole (8) derivatives has been developed using plant extracts. The different plant part extracts of Terminalia chebula, Punica granatum, and Aegle marmelos have been studied. The aqueous fruit extract of Terminalia chebula gave better results. The synthetic method has been optimized with respect to plant extract quantity, pH of the reaction, and yield. The developed protocol showed several advantages like mild reaction conditions, short reaction time, high yield, and reduced environmental impact.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • An Efficient Alternative to the Total Synthesis of Isophytol

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      Abstract: An improved and alternative method for the total synthesis of isophytol from citral via using pseudoionone intermediate was developed and described in this manuscript. This alternative commercially viable approach involves six steps and it represents an alternative method commercially viable over existing published synthetic methods in the literature. This goal was achieved by developing and optimizing an efficient and high yield procedure for the synthesis of a key intermediate i.e. 6,10,14-trimethylpentadectrimethylpentadec-5-en-2-one, by reacting 2-methoxypropene with a tertiary alcohol (3,7,11-trimethyldodec-1-ene-3-ol). Isophytol was provided in 58-60% overall yield from citral with>99% purity, evaluated by TLC, GC, and NMR.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • Synthesis and Evaluation of Isatin Schiff Bases Against Plant Pathogens
           Validated Through Aspartyl Protease and Acetylcholine Binding Proteins
           Docked Studies

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      Abstract: Schiff bases of isatin were synthesized by reacting isatin with substituted aromatic amines and were characterized by UV-Visible, 1HNMR, 13CNMR, IR and micro analytical data. All the synthesized isatin Schiff bases were screened in vitro against wheat pathogenic fungi Bipolaris sorokiniana, Alternaria triticina using spore inhibition technique and brinjal parasite- Meloidogyne incognita by egg hatch inhibition and J2 mortality. The in vitro study and docking simulation studies revealed that the 3-(2, 4, 5-trichlorophenylimino) indolin-2-one 6f and 3-(2, 4- dinitrophenylimino) indolin-2-one 6c substituted with tri-halogen and dinitro electron withdrawing groups were found to be promising antipathogenic candidates. The possible binding interactions of tested compounds with Aspartyl protease and Acetylcholine binding proteins were analyzed through molecular docking.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • The Synthesis of 1,3-Thiazolium Ionic Liquids Combined with 1,2,4-
           Triazole-5-One by Different Synthetic Pathways

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      Abstract: Ionic liquids (ILs) are essential in green chemistry. In this study, we have synthesized and characterized novel ILs that have two heterocyclic ring systems. IL is synthesized by two different synthetic pathways. The first synthetic pathway is method A that consists of two steps. The first step of reactions involved the synthesis of IL with 1,3-thiazole ring systems, followed by the second step synthesis of 1,3-thiazole and 1,2,4-triazole-5-on ring systems. The second synthetic pathway is method B that consists of three steps. IL was synthesized by both methods A and B to confirm that the FT-IR, 1HNMR, 13C-NMR, and Mass analysis was performed on the chemical structures.
      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
  • Acknowledgements to Reviewers

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      PubDate: Wed, 15 Dec 2021 20:02:06 -070
       
 
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