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ORGANIC CHEMISTRY (47 journals)

Showing 1 - 41 of 41 Journals sorted alphabetically
ACS Omega     Open Access   (Followers: 2)
Advances in Image and Video Processing     Open Access   (Followers: 18)
Advances in Physical Organic Chemistry     Full-text available via subscription   (Followers: 4)
Advances in Redox Research     Open Access   (Followers: 4)
American Journal of Organic Chemistry     Open Access   (Followers: 15)
Asian Journal of Organic Chemistry     Hybrid Journal   (Followers: 4)
Beilstein Journal of Organic Chemistry     Open Access   (Followers: 13)
Biochemia Medica     Open Access  
Current Organic Chemistry     Hybrid Journal   (Followers: 14)
Current Organic Synthesis     Hybrid Journal   (Followers: 12)
European Journal of Organic Chemistry     Hybrid Journal   (Followers: 59)
Herbal Medicine: Open Access     Open Access  
International Journal of Organic Chemistry     Open Access   (Followers: 9)
International Journal of Polymeric Materials     Hybrid Journal   (Followers: 6)
Journal of Bioactive and Compatible Polymers     Hybrid Journal   (Followers: 2)
Journal of Biomaterials Science, Polymer Edition     Hybrid Journal   (Followers: 9)
Journal of Organic Semiconductors     Open Access   (Followers: 6)
Journal of Peptide Science     Hybrid Journal   (Followers: 14)
Journal of Physical Organic Chemistry     Hybrid Journal   (Followers: 8)
Journal of Physiology and Biochemistry     Hybrid Journal   (Followers: 3)
Journal of Progressive Research in Chemistry     Open Access  
Journal of Proteins and Proteomics     Open Access   (Followers: 2)
Mini-Reviews in Organic Chemistry     Hybrid Journal   (Followers: 10)
Nigerian Journal of Chemical Research     Full-text available via subscription   (Followers: 1)
Open Journal of Organic Polymer Materials     Open Access   (Followers: 1)
Organic & Biomolecular Chemistry     Hybrid Journal   (Followers: 56)
Organic and Medicinal Chemistry Letters     Open Access   (Followers: 5)
Organic Chemistry : Current Research     Open Access   (Followers: 12)
Organic Chemistry Frontiers     Hybrid Journal   (Followers: 9)
Organic Chemistry International     Open Access   (Followers: 7)
Organic Geochemistry     Hybrid Journal   (Followers: 3)
Organic Letters     Hybrid Journal   (Followers: 92)
Organic Preparations and Procedures International: The New Journal for Organic Synthesis     Hybrid Journal   (Followers: 3)
Organic Process Research & Development     Hybrid Journal   (Followers: 32)
Progress in Organic Coatings     Hybrid Journal   (Followers: 7)
Reports in Organic Chemistry     Open Access   (Followers: 7)
Russian Journal of Organic Chemistry     Hybrid Journal   (Followers: 3)
Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry     Hybrid Journal   (Followers: 31)
The Journal of Organic Chemistry     Hybrid Journal   (Followers: 135)
Vibrational Spectroscopy     Hybrid Journal   (Followers: 11)
World Journal of Organic Chemistry     Open Access   (Followers: 5)
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Beilstein Journal of Organic Chemistry
Journal Prestige (SJR): 0.929
Citation Impact (citeScore): 2
Number of Followers: 13  

  This is an Open Access Journal Open Access journal
ISSN (Print) 1860-5397
Published by Beilstein-Institut Homepage  [2 journals]
  • Regioselective synthesis of methyl
           5-(N-Boc-cycloaminyl)-1,2-oxazole-4-carboxylates as new amino acid-like
           building blocks

    • Authors: Jolita Bruzgulienė; Greta Račkauskienė, Aurimas Bieliauskas, Vaida Milišiūnaitė, Miglė Dagilienė, Gita Matulevičiūtė, Vytas Martynaitis, Sonata Krikštolaitytė, Frank A. Sløk Algirdas Šačkus
      Abstract: A convenient and efficient synthesis of novel achiral and chiral heterocyclic amino acid-like building blocks was developed. Regioisomeric methyl 5-(N-Boc-cycloaminyl)-1,2-oxazole-4-carboxylates were prepared by the reaction of β-enamino ketoesters (including azetidine, pyrrolidine or piperidine enamines) with hydroxylamine hydrochloride. Unambiguous structural assignments were based on chiral HPLC analysis, 1H, 13C, and 15N NMR spectroscopy, HRMS, and single-crystal X-ray diffraction data.Beilstein J. Org. Chem. 2022, 18, 102–109. doi:10.3762/bjoc.18.11
      Keywords: β-enamino ketoesters; heterocyclic amino acids; 15N-labeled 1,2-oxazole; NMR (1H; 13C; 15N); 1,2-oxazole (isoxazole); X-ray structure analysis
      Citation: Beilstein Journal of Organic Chemistry 2022 18:11
      PubDate: Wed, 12 Jan 2022 09:56:00 GMT
      DOI: 10.3762/bjoc.18.11
       
  • Chemical and chemoenzymatic routes to bridged
           homoarabinofuranosylpyrimidines: Bicyclic AZT analogues

    • Authors: Sandeep Kumar; Jyotirmoy Maity, Banty Kumar, Sumit Kumar Ashok K. Prasad
      Abstract: Conformationally restricted diastereomeric homoarabinofuranosylpyrimidines (AZT analogue), i.e., (5′R)-3′-azido-3′-deoxy-2′-O,5′-C-bridged-β-ᴅ-homoarabinofuranosylthymine and -uracil had been synthesized starting from diacetone ᴅ-glucofuranose following chemoenzymatic and chemical routes in 34–35% and 24–25% overall yields, respectively. The quantitative and diastereoselective acetylation of primary hydroxy over two secondary hydroxy groups present in the key nucleoside precursor was mediated with Lipozyme® TL IM in 2-methyltetrahydrofuran following a chemoenzymatic pathway. Whereas, the protection of the primary hydroxy over the lone secondary hydroxy group in the key azido sugar precursor was achieved using bulky tert-butyldiphenylsilyl chloride (TBDPS-Cl) in pyridine in 92% yield following a chemical synthetic pathway. The chemoenzymatic method was found to be superior over the chemical method in respect of the number of synthetic steps and overall yield of the final product.Beilstein J. Org. Chem. 2022, 18, 95–101. doi:10.3762/bjoc.18.10
      Keywords: bicyclic AZT analogues; bridged homoarabinofuranosylpyrimidine nucleosides; chemical pathway; Lipozyme® TL IM; regioselective enzymatic acetylation
      Citation: Beilstein Journal of Organic Chemistry 2022 18:10
      PubDate: Tue, 11 Jan 2022 10:28:00 GMT
      DOI: 10.3762/bjoc.18.10
       
  • Chemoselective N-acylation of indoles using thioesters as acyl source

    • Authors: Tianri Du; Xiangmu Wei, Honghong Xu, Xin Zhang, Ruiru Fang, Zheng Yuan, Zhi Liang Yahui Li
      Abstract: The selective acylation of indoles often requires sensitive and reactive acyl chloride derivatives. Here, we report a mild, efficient, functional group tolerant, and highly chemoselective N-acylation of indoles using thioesters as a stable acyl source. A series of indoleamides have been obtained with moderate to good yields. In addition, heterocycles, such as carbazole, can also be used as nucleophiles in this reaction.Beilstein J. Org. Chem. 2022, 18, 89–94. doi:10.3762/bjoc.18.9
      Keywords: indole; N-acylation; nucleophilic substitution; thioesters
      Citation: Beilstein Journal of Organic Chemistry 2022 18:9
      PubDate: Mon, 10 Jan 2022 10:23:00 GMT
      DOI: 10.3762/bjoc.18.9
       
  • Earth-abundant 3d transition metals on the rise in catalysis

    • Authors: Nikolaos Kaplaneris; Lutz Ackermann
      Abstract: Beilstein J. Org. Chem. 2022, 18, 86–88. doi:10.3762/bjoc.18.8
      Keywords: C–H activation; 3d transition metals; green chemistry; late-stage functionalization; sustainability
      Citation: Beilstein Journal of Organic Chemistry 2022 18:8
      PubDate: Fri, 07 Jan 2022 10:15:00 GMT
      DOI: 10.3762/bjoc.18.8
       
  • Efficient and regioselective synthesis of dihydroxy-substituted
           2-aminocyclooctane-1-carboxylic acid and its bicyclic derivatives

    • Authors: İlknur Polat; Selçuk Eşsiz, Uğur Bozkaya Emine Salamci
      Abstract: The first synthesis of 2-amino-3,4-dihydroxycyclooctane-1-carboxylic acid, methyl 6-hydroxy-9-oxo-8-oxabicyclo[5.2.1]decan-10-yl)carbamate, and 10-amino-6-hydroxy-8-oxabicyclo[5.2.1]decan-9-one starting from cis-9-azabicyclo[6.2.0]dec-6-en-10-one is described. cis-9-Azabicyclo[6.2.0]dec-6-en-10-one was transformed into the corresponding amino ester and its protected amine. Oxidation of the double bond in the N-Boc-protected methyl 2-aminocyclooct-3-ene-1-carboxylate then delivered the targeted amino acid and its derivatives. Density-functional theory (DFT) computations were used to explain the reaction mechanism for the ring opening of the epoxide and the formation of five-membered lactones. The stereochemistry of the synthesized compounds was determined by 1D and 2D NMR spectroscopy. The configuration of methyl 6-hydroxy-9-oxo-8-oxabicyclo[5.2.1]decan-10-yl)carbamate was confirmed by X-ray diffraction.Beilstein J. Org. Chem. 2022, 18, 77–85. doi:10.3762/bjoc.18.7
      Keywords: aminocyclitol; azidolysis; bicyclic β-lactam; bicyclic lactone; cyclic β-amino acids; DFT
      Citation: Beilstein Journal of Organic Chemistry 2022 18:7
      PubDate: Thu, 06 Jan 2022 11:05:00 GMT
      DOI: 10.3762/bjoc.18.7
       
  • Efficient synthesis of ethyl 2-(oxazolin-2-yl)alkanoates via
           ethoxycarbonylketene-induced electrophilic ring expansion of aziridines

    • Authors: Yelong Lei; Jiaxi Xu
      Abstract: Alkyl 2-diazo-3-oxoalkanoates generate alkoxycarbonylketenes, which undergo an electrophilic ring expansion with aziridines to afford alkyl 2-(oxazolin-2-yl)alkanoates in good to excellent yields under microwave heating. The method is a convenient and clean reaction without any activators and catalysts and can be also applied in the synthesis of 2-(oxazolin-2-yl)alkanamides and 1-(oxazolin-2-yl)alkylphosphonates.Beilstein J. Org. Chem. 2022, 18, 70–76. doi:10.3762/bjoc.18.6
      Keywords: aziridine; diazooxoester; diazo compound; ketene; oxazoline; ring expansion
      Citation: Beilstein Journal of Organic Chemistry 2022 18:6
      PubDate: Wed, 05 Jan 2022 14:46:00 GMT
      DOI: 10.3762/bjoc.18.6
       
  • 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis

    • Authors: Ruan Carlos B. Ribeiro; Patricia G. Ferreira, Amanda de A. Borges, Luana da S. M. Forezi, Fernando de Carvalho da Silva Vitor F. Ferreira
      Abstract: Several low molecular weight naphthoquinones are very useful in organic synthesis. These compounds have given rise to thousands of other naphthoquinones that have been tested against various microorganisms and pharmacological targets, including being used in the preparation of several drugs that are on the pharmaceutical market. Among these naphthoquinones, the series of compounds prepared from 1,2-naphthoquinone-4-sulfonic acid salts (β-NQS) stands out. In addition to being used in organic synthesis, they are excellent analytical derivatization reagents to spectrophotometrically determine drugs containing primary and secondary amino groups. This review summarizes the literature involving β-NQS.Beilstein J. Org. Chem. 2022, 18, 53–69. doi:10.3762/bjoc.18.5
      Keywords: biological activities; derivatization reagents; β-NQS; organic synthesis
      Citation: Beilstein Journal of Organic Chemistry 2022 18:5
      PubDate: Wed, 05 Jan 2022 09:45:00 GMT
      DOI: 10.3762/bjoc.18.5
       
  • Recent advances and perspectives in ruthenium-catalyzed cyanation
           reactions

    • Authors: Thaipparambil Aneeja; Cheriya Mukkolakkal Abdulla Afsina, Padinjare Veetil Saranya Gopinathan Anilkumar
      Abstract: The cyanation reaction has achieved rapid progress in recent times. The ability to exhibit multiple oxidation states increased the demand of ruthenium in the field of catalysis. These cyanation reactions have wide application in pharmacological and biological fields. This review gives an overview of the ruthenium-catalyzed cyanation reactions covering literature up to 2021.Beilstein J. Org. Chem. 2022, 18, 37–52. doi:10.3762/bjoc.18.4
      Keywords: cyanation; nitriles; photocatalyst; ruthenium; tertiary amines
      Citation: Beilstein Journal of Organic Chemistry 2022 18:4
      PubDate: Tue, 04 Jan 2022 15:28:00 GMT
      DOI: 10.3762/bjoc.18.4
       
  • Bifunctional thiourea-catalyzed asymmetric [3 + 2] annulation reactions of
           2-isothiocyanato-1-indanones with barbiturate-based olefins

    • Authors: Jiang-Song Zhai; Da-Ming Du
      Abstract: Bifunctional thiourea-catalyzed asymmetric [3 + 2] annulation reactions of 2-isothiocyanato-1-indanones with barbiturate-based olefins have been developed to afford chiral dispiro[indene-pyrrolidine-pyrimidine]s. Through this strategy, the target products could be obtained in good to excellent yields with excellent stereoselectivities. In addition, the synthetic utility was verified through a gram-scale synthesis, one-pot three-component reactions and further transformation experiments of the products.Beilstein J. Org. Chem. 2022, 18, 25–36. doi:10.3762/bjoc.18.3
      Keywords: asymmetric catalysis; cyclization reaction; Michael addition; one-pot three-component reaction; spirobarbiturates
      Citation: Beilstein Journal of Organic Chemistry 2022 18:3
      PubDate: Tue, 04 Jan 2022 09:23:00 GMT
      DOI: 10.3762/bjoc.18.3
       
  • The enzyme mechanism of patchoulol synthase

    • Authors: Houchao Xu; Bernd Goldfuss, Gregor Schnakenburg Jeroen S. Dickschat
      Abstract: Different mechanisms for the cyclisation of farnesyl pyrophosphate to patchoulol by the patchoulol synthase are discussed in the literature. They are based on isotopic labelling experiments, but the results from these experiments are contradictory. The present work reports on a reinvestigation of patchoulol biosynthesis by isotopic labelling experiments and computational chemistry. The results are in favour of a pathway through the neutral intermediates germacrene A and α-bulnesene that are both reactivated by protonation for further cyclisation steps, while previously discussed intra- and intermolecular hydrogen transfers are not supported. Furthermore, the isolation of the new natural product (2S,3S,7S,10R)-guaia-1,11-dien-10-ol from patchouli oil is reported.Beilstein J. Org. Chem. 2022, 18, 13–24. doi:10.3762/bjoc.18.2
      Keywords: biosynthesis; DFT calculations; enzyme mechanisms; isotopes; terpenes
      Citation: Beilstein Journal of Organic Chemistry 2022 18:2
      PubDate: Mon, 03 Jan 2022 15:09:00 GMT
      DOI: 10.3762/bjoc.18.2
       
 
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