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  Subjects -> SCIENCES: COMPREHENSIVE WORKS (Total: 374 journals)
Showing 201 - 265 of 265 Journals sorted by number of followers
Revista Científica de la Universidad Nacional del Este     Open Access   (Followers: 12)
History of Science and Technology     Open Access   (Followers: 5)
Orbis Cógnita : Revista Científica     Open Access   (Followers: 4)
Research Policy : X     Open Access   (Followers: 4)
Data     Open Access   (Followers: 4)
Advanced Theory and Simulations     Hybrid Journal   (Followers: 4)
Frontiers in Climate     Open Access   (Followers: 4)
MUST : Journal of Mathematics Education, Science and Technology     Open Access   (Followers: 4)
Journal of the Indian Institute of Science     Hybrid Journal   (Followers: 4)
Discover Sustainability     Open Access   (Followers: 3)
Journal of Composites Science     Open Access   (Followers: 3)
Research     Open Access   (Followers: 3)
Journal of Big History     Open Access   (Followers: 3)
Patterns     Open Access   (Followers: 3)
People and Nature     Open Access   (Followers: 3)
Science & Technology Studies     Open Access   (Followers: 3)
Citizen Science : Theory and Practice     Open Access   (Followers: 2)
Indonesian Journal of Science and Mathematics Education     Open Access   (Followers: 2)
International Journal of Culture and Modernity     Open Access   (Followers: 2)
Experimental Results     Open Access   (Followers: 1)
Global Journal of Science Frontier Research     Open Access   (Followers: 1)
International Journal of Innovative Research and Scientific Studies     Open Access   (Followers: 1)
Acta Scientifica Malaysia     Open Access   (Followers: 1)
Applied Mathematics and Nonlinear Sciences     Open Access   (Followers: 1)
Bilge International Journal of Science and Technology Research     Open Access   (Followers: 1)
Journal of Science and Engineering     Open Access   (Followers: 1)
Uluslararası Bilimsel Araştırmalar Dergisi (IBAD)     Open Access   (Followers: 1)
Journal of Science and Technology     Open Access   (Followers: 1)
AAS Open Research     Open Access   (Followers: 1)
ARPHA Conference Abstracts     Open Access   (Followers: 1)
Revista Vivências em Ensino de Ciências     Open Access   (Followers: 1)
iScience     Open Access   (Followers: 1)
Scientonomy : Journal for the Science of Science     Open Access   (Followers: 1)
Futures & Foresight Science     Hybrid Journal   (Followers: 1)
International Journal of Research in Science     Open Access   (Followers: 1)
Jaunujų mokslininkų darbai     Open Access   (Followers: 1)
Impact     Open Access   (Followers: 1)
Revista Saber Digital     Open Access   (Followers: 1)
Fundamental Research     Open Access  
BJHS Themes     Open Access  
South American Sciences     Open Access  
Middle European Scientific Bulletin     Open Access  
Journal of Alasmarya University     Open Access  
Research Integrity and Peer Review     Open Access  
Natural Sciences Education     Hybrid Journal  
Proceedings of the Indian National Science Academy     Full-text available via subscription  
Indian Journal of History of Science     Hybrid Journal  
RAC: Revista Angolana de Ciências     Open Access  
The Innovation     Open Access  
Journal of Responsible Technology     Open Access  
Natural Sciences     Open Access  
Revista de la Sociedad Científica del Paraguay     Open Access  
Rekayasa     Open Access  
Rihan Journal for Scientific Publishing     Open Access  
Türk Bilim ve Mühendislik Dergisi     Open Access  
ArtefaCToS : Revista de estudios sobre la ciencia y la tecnología     Open Access  
Ethiopian Journal of Sciences and Sustainable Development     Open Access  
Vilnius University Proceedings     Open Access  
Sciential     Open Access  
ARPHA Proceedings     Open Access  
Gaudium Sciendi     Open Access  
Crea Ciencia Revista Científica     Open Access  
Rafidain Journal of Science     Open Access  
Journal of Al-Qadisiyah for Pure Science     Open Access  
Revista Tecnológica     Open Access  
Himalayan Journal of Science and Technology     Open Access  
International Journal of Academic Research in Business, Arts & Science     Open Access  
Universidad, Ciencia y Tecnología     Open Access  
Fides et Ratio : Revista de Difusión Cultural y Científica     Open Access  
Acta Nova     Open Access  
Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales     Open Access  
Entre Ciencia e Ingeniería     Open Access  
Revista Politécnica     Open Access  
Reportes Científicos de la FaCEN     Open Access  
Jurnal Ilmiah Ilmu Terapan Universitas Jambi : JIITUJ     Open Access  
Revista Eletrônica Ludus Scientiae     Open Access  
Emergent Scientist     Open Access  
Journal of Scientific Research and Reports     Open Access  
Asian Journal of Advanced Research and Reports     Open Access  
Archives of Current Research International     Open Access  
Advances in Research     Open Access  
International Journal of Applied Science     Open Access  
Iranian Journal of Science and Technology, Transactions A : Science     Hybrid Journal  
J : Multidisciplinary Scientific Journal     Open Access  
Revista Binacional Brasil - Argentina: Diálogo entre as ciências     Open Access  
Revista Ciencia y Tecnología     Open Access  
Journal of Institute of Science and Technology     Open Access  
Journal of Science (JSc)     Open Access  
WikiJournal of Science     Open Access  
Acta Materialia Transilvanica     Open Access  
Integrated Research Advances     Open Access  
PENDIPA : Journal of Science Education     Open Access  
Open Conference Proceedings Journal     Open Access  
Naturen     Full-text available via subscription  
Ekaia : EHUko Zientzia eta Teknologia aldizkaria     Open Access  
Sci     Open Access  
Maskana     Open Access  
Hoosier Science Teacher     Open Access  
Reports in Advances of Physical Sciences     Open Access  
Facets     Open Access  
Adıyaman University Journal of Science     Open Access  
Revista Brasileira de Iniciação Científica     Open Access  
Communications Faculty of Sciences University of Ankara Series A2-A3 Physical Sciences and Engineering     Open Access  
Scientific African     Open Access  
Scientific Journal of Mehmet Akif Ersoy University     Open Access  
Black Sea Journal of Engineering and Science     Open Access  
Fırat University Turkish Journal of Science & Technology     Open Access  
Gazi University Journal of Science     Open Access  
Middle East Journal of Science     Open Access  
International Journal of Computational and Experimental Science and Engineering (IJCESEN)     Open Access  
International Journal of Engineering, Technology and Natural Sciences     Open Access  
Bulletin of the National Research Centre     Open Access  
Uni-pluriversidad     Open Access  
ConCiencia     Open Access  
Ciencia y Tecnología     Open Access  
Revista Bases de la Ciencia     Open Access  
Elkawnie : Journal of Islamic Science and Technology     Open Access  
Ciência ET Praxis     Open Access  
Arab Journal of Basic and Applied Sciences     Open Access  
International Annals of Science     Open Access  
Science Heritage Journal     Open Access  
Avrasya Terim Dergisi     Open Access  
International Scientific and Vocational Studies Journal     Open Access  
TÜBAV Bilim Dergisi     Open Access  
LOGIKA Jurnal Ilmiah Lemlit Unswagati Cirebon     Open Access  
Dalat University Journal of Science     Open Access  
Investiga : TEC     Open Access  
Investigación Joven     Open Access  
Respuestas     Open Access  
Science Diliman     Open Access  
Instruments     Open Access  
Revista Científica y Tecnológica UPSE     Open Access  
HardwareX     Open Access  
Sultan Qaboos University Journal for Science     Open Access  
Borneo Journal of Resource Science and Technology     Open Access  
Sainstek : Jurnal Sains dan Teknologi     Open Access  
Revista de Información Científica     Open Access  
Indonesian Journal of Fundamental Sciences     Open Access  
Sainteknol : Jurnal Sains dan Teknologi     Open Access  
Jurnal Natural     Open Access  
Frontiers for Young Minds     Open Access  
Revista Ciência, Tecnologia & Ambiente     Open Access  
Journal of Indian Council of Philosophical Research     Hybrid Journal  
Journal of Negative and No Positive Results     Open Access  
Revista Conhecimento Online     Open Access  
Nova     Open Access  
CienciaUAT     Open Access  
Enseñanza de las Ciencias : Revista de Investigación y Experiencias Didácticas     Open Access  
Makara Journal of Science     Open Access  
Jurnal Sains Dasar     Open Access  
Indonesian Journal of Science and Technology     Open Access  
Ethiopian Journal of Science and Technology     Open Access  
Jurnal Matematika, Sains, Dan Teknologi     Open Access  
Heidelberger Jahrbücher Online     Open Access  
ARO. The Scientific Journal of Koya University     Open Access  
International Journal of Recent Contributions from Engineering, Science & IT     Open Access  
Estação Científica (UNIFAP)     Open Access  
The Winnower     Open Access  

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Proceedings of the Indian National Science Academy
Number of Followers: 0  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 0370-0046 - ISSN (Online) 2454-9983
Published by Springer-Verlag Homepage  [2469 journals]
  • Precision diabetes is becoming a reality in India

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      Abstract: Abstract The terms Precision Medicine and Personalized Medicine are used interchangeably but there are subtle differences between the two. Obtaining scientific information (for example, about genotype and phenotype and biomarkers) and then deciding the treatment is Precision Medicine. Personalized Medicine on the other hand refers to taking other factors pertaining to the patient (e.g., preferences, socioeconomic factors and patient) into account and then prescribing a treatment that is suitable for the patient. This review presents the concept of Precision Medicine as applied to diabetes (Precision Diabetes). It discusses planning suitable treatment strategies for different subtypes of diabetes and incorporating specific treatment plans (personalized treatment) for patients with diabetes. It also addresses the challenges in delivering precision diabetes treatment to all people with diabetes. Finally, it outlines where Precision Diabetes has already become a reality in the diabetes clinic e.g., in Monogenic diabetes and where it is still a work in progress (e.g., in type 1 and type 2 diabetes).
      PubDate: 2022-09-29
       
  • Li doped graphitic carbon nitride based solar light responding
           photocatalyst for organic water pollutants degradation

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      Abstract: Abstract In this study we have synthesised the alkali metal modified g-C3N4 by following a facile method of thermal polymerisation. The lithium doped g-C3N4 so obtained has been characterised to understand various structural, morphological and optical aspects of the samples. The photocatalytic potential of lithium doped g-C3N4 has been analysed for degradation of organic dyes crystal violet, methyl orange, rhodamine b, rose bengal under natural solar irradiation. The performed study revealed that li doped g-C3N4 can act as a potential solar light responding photocatalytic material for various organic dyes degradation and can be explored further for other environmental applications.
      PubDate: 2022-09-29
       
  • A comprehensive review on ethnobotanical, medicinal and nutritional
           potential of walnut (Juglans regia L.)

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      Abstract: Abstract Juglans regia L. commonly known as walnut is used as the most extensive and economical tree in the world. This review aims to study the ethnomedicinal, phytochemical and pharmacological potential of walnut. The literature has been collected from different online sources like science Direct, Scopus, ResearchGate, Google Scholar, PubMed, etc. based on inclusion and exclusion criteria. An ethnomedicinal survey has also been conducted to document the traditional knowledge and uses of walnut among the local peoples of the Union Territory of Jammu and Kashmir. On surveying the local peoples in the different major walnut-producing areas, it has been followed that the walnut is locally used as a medicinal, nutritional, and commercial plant to treat common diseases and disorders in the locality. The survey has been conducted first time in the area and no study has been reported till now in the Jammu Division while some work has been reported in the Kashmir Division. Among the many bioactive compounds present in various plant parts, Juglone has been reported a significant anti-cancer compound in treating deadly cancer. This systematic review describes the significant knowledge and traditional information collected on ethnomedicinal uses, phytochemistry, habitat, macro-morphology, area of distribution, and pharmacological importance.
      PubDate: 2022-09-22
       
  • Correction: First report on late Miocene (Tortonian: ~ 11–10 Ma)
           charophyte gyrogonites from Tapar, Kachchh District, Gujarat State,
           western India

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      PubDate: 2022-09-19
       
  • Editorial

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      PubDate: 2022-09-19
       
  • Ensure the dynamic identity and PUF based authenticated key settlement
           approach for the IoT infrastructure

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      Abstract: Abstract With technological advancements, the dependency on the Internet of things (IoT) has increased. The spectrum of IoT application domain becomes larger day by day. It converts the existing services into smart services. The evolution brings lot of security challenges hand in hand with IoT paradigms. This is due to the limitation of IoT devices like, low computational capabilities, small storage medium, less power back up and low processing speed, etc. To overcome these limitations, a proper authentication technique must be required to do the trust management in a heterogeneous IoT environment and secure all kinds of traffic. In this research document, a dynamic identity-based authentication approach is introduced for IoT environment, which utilizes very lightweight physical unclonable function, one-way hashing function and exclusive-OR(XOR) function to make the scheme lighter. Broadly accepted the Real or Random (RoR) model and the Burrows Abadi Needham logic (BAN logic) are used here, to check the security and the correctness of the devised protocol. In addition to that, the software simulation tool, Automated validation of Internet security protocols and applications (AVISPA) has proved that, the recommended protocol is safe and secure from various attacks. Furthermore, the comparative performance analysis exhibits the supremacy of the recommended scheme over the analogous schemes w.r.t computational power, memory usage, and communication overhead.
      PubDate: 2022-09-19
       
  • A brief review on novel biomarkers identified and advanced biosensing
           

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      Abstract: Abstract Advanced biosensor technology research is imperative for the management of infectious disease outbreaks such as Japanese Encephalitis (JE), a zoonotic disease caused by the flavivirus JE virus (JEV) which is transmitted to humans (dead-end hosts) from the amplification host, pigs, via mosquitoes. To avoid future pandemic scenarios, proactive research rather than responsive research in the field of diagnostics is a requirement for development of rapid, sensitive and specific screening detection methods. In this mini-review, we have critically compared and evaluated the different types of biomarkers (antigen, antibody, nucleic acid) identified for JEV diagnostics and their specific roles in the manifestation of the infection which may be potentially used for therapeutics and drug development as no treatment is available for JE. Furthermore, different biosensors developed for the detection of JEV biomarkers have been discussed in detail to give an overview of the working principles (electrochemical, optical, etc.), fabrication components (signal amplifier, bioreceptor, etc.), detection limits and response times. This review provides a compact compiled base on available JEV diagnostic research work being currently carried out along with their limitations, future prospective, and major challenges faced. This will enable future development of rapid point-of-care diagnostic screening methods for JEV infection management, which may help reduce number of fatalities.
      PubDate: 2022-09-19
       
  • Calculation of interfacial free energy for binary hard sphere mixtures

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      Abstract: Abstract In this work, we present a method to calculate interfacial free energy for a binary hard sphere fluid mixture in coexistence with disordered face centered cubic solid. Monte Carlo(MC) Simulations are performed at 0.97 size ratio of small to large particle diameters. Interfacial free energy is calculated across composition for (100),(110) and (111) orientations of the substitutionally disordered solid phase along the coexistence line. Our calculations are based on the concept of Gibbs equimolar dividing surface. First, we calculate the surface excess quantities using the thermodynamic properties obtained from MC simulations then we integrate rewritten equivalent form of Gibbs adsorption equation with respect to pressure using pure hard sphere system interfacial free energy as a reference to get binary hard sphere mixture interfacial free energy. In our simulations we also varied cross sectional areas of solid exposed to fluid mixtures by varying system sizes, the computed interfacial free energies are consistent within error limits and confirms to scaling laws.
      PubDate: 2022-09-15
       
  • Pollution complexity quantification using NPI and HPI of River Ganga
           system in Himalayan Region

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      Abstract: Abstract The Ganga river system is a life-sustaining system that offers freshwater to millions in India.This research demonstrated the Ganga River's water quality based on data collected from 20 locations from Upper, middle and foot hills of Garhwal Himalayas. The present study combines the Single-factor Pollution Index (Pi), Nemerow Pollution Index (NPI),Heavy Metal Pollution Index (HPI), and chemo-metric models (Principal Component Analysis: PCA and Cluster Analysis: CA) to establish a cause-effect relationship between any change in water quality and their sources.The water samples were analyzed to measure the concentrations of 10 potentially toxic elements (PTEs) such as Zn, Pb, Mn, Fe, Cu, Al, Ni, Cd, Mg, and Co. Results revealed that river water is highly contaminated (HPI > 30) at downstream sitescompared to upstream sites,resulting froma rapid increase in agricultural, industrial, and domestic activities. Regular monitoring and prevention of pollution techniques are required to protect river water from heavy metal toxicity. Some of the heavy metals tested were beyond industry guidelines, necessitating a health risk assessment. The health risk evaluation for all sites revealed that no single heavy metal is particularly hazardous, but the cumulative impact, as indicated by the hazard index, is (HI). For all seasons, HI far surpassed the threshold value (1). This is a reason for concern for both adults and children who have ingested the water. Heavy metal pollution was geogenic, with anthropogenic activities exacerbating it.
      PubDate: 2022-09-15
       
  • Anti-plasmodial and mosquitocidal potential of metallic nanoparticles: a
           perspective

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      Abstract: The incidence of malaria, a mosquito-borne infectious disease exists throughout the tropical and subtropical regions. Various factors restrict the effective control of malaria including their increasingly resistance to existing anti-malarial drugs. New strategies for malaria management are needed at both the fronts for the search of new anti-malarial agent and control of vector anopheles in order to restrict the transmission of malaria. Mosquitoes are the most important single group of insects in terms of public health importance, which transmit a number of diseases, such as malaria, filariasis, dengue, Japanese encephalitis, etc., causing millions of deaths every year. Although many strategies including chemicals and phytochemicals has been well explored for parasite and vector control, in recent years, metal nanoparticles are gaining attention as potential material in this domain. This review has summarized, the present status of some metallic nanoparticles as anti-plasmodial and mosquitocidal activities in perspective of malaria management. Graphical abstract Fig. Metallic nanoparticles potential with Anti-plasmodial and Mosquitocidal activity
      PubDate: 2022-09-13
       
  • Pyocyanin pigment from Pseudomonas species: Source of a dye and
           antimicrobial textile finish—a review

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      Abstract: Abstract Artificial colours are extensively used in various industries like food, textiles, cosmetics and pharmaceuticals. Synthetic pigments pose toxicity threats and this has provoked an interest in the field of microbial colours and dyes. Pigment producing microorganisms exhibit a promising potential in overcoming current challenges. These pigments are biodegradable and eco-friendly. At present, natural pigments, especially microbial pigments hold great significance within the market. Numerous microorganisms produce colored pigments. This review focuses on the antimicrobial and antifungal activity of pyocyanin, pigment from Pseudomonas aeruginosa. It may find application in preparation of sheets and gown for medical and hospital use. Various fermentation techniques are discussed in view of their production by some important microorganisms. Further, it also sheds light on the possibility of using this pigment as textile colourant or dye which can be used to colour cotton, wool and silk fabrics.
      PubDate: 2022-09-13
       
  • Population status of house sparrow (Passer domesticus L.) and its
           association with native bird species in and around Dehradun City of
           Uttarakhand, India

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      Abstract: Abstract Recent studies have indicated a significant decline in the population of the house sparrow (Passer domesticus L.) at the global level. In India also, the house sparrow population is being drastically decreased. Considering the issue, an attempt has been made to monitor the current status of house sparrows across Dehradun City of Uttarakhand from 2017 to 2019. The line transect method was used for bird surveys in the three habitats (high-density urban area, low-density urban area, and suburban area). The results showed that the population of house sparrows was significantly higher in the suburban area (84.19 ± 8.05) as compared to those in high-density (12.75 ± 2.02) and low-density (42.97 ± 4.74) urban areas. Similarly, the number of active nests was also found higher in a suburban area as compared to other areas. Additionally, a total of 87 co-occurring avian species were observed in the study area with maximum avian diversity reported in low-density (H = 2.85) followed by suburban (H = 2.67) and high-density urban areas (H = 2.12) respectively. This study suggested that the regular monitoring of house sparrows and co-occurring avian species is important to understand the population trend of the house sparrow in the study area.
      PubDate: 2022-09-09
       
  • Multi-sensor target data detection method based on improved deep learning

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      Abstract: Abstract Aiming at the problems of low detection accuracy and long detection time in the traditional multi-sensor target data detection method, a multi-sensor target data detection method based on improved deep learning is proposed. A regional nomination network model is built to locate all rectangular areas where multi-sensor targets may exist. A sample acquisition model is established by fusing multi-sensor target data in this area in combination with the storage structure of multi-sensor target data to collect multi-sensor target data and filter the collected target data. The histogram feature method is used to extract the processed multi-sensor target data features and the extracted multi-sensor target data features are input into the neural network training samples. The square error function is used to calculate the sample deviation and the deviation is corrected by the deviation gradient sinking method. Finally, the multi-sensor target data detection results are output. Simulation results show that the proposed method has high accuracy, low false detection rate and short detection time along with applicability.
      PubDate: 2022-09-07
       
  • Nutrition influences nervous system development by regulating neural stem
           cell homeostasis

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      Abstract: Abstract Like the general growth of an organism, nervous system development also depends heavily on nutrition. This review discusses how the brain-food axis works and how nutritional factors impact neural stem cell (NSC) behavior in vertebrate and invertebrate systems. Various aspects of NSC homeostasis, from proliferation, quiescence, and differentiation to timely elimination during development and adult life, depend on nutrition and metabolism. Here we have reviewed the role of macro-and micronutrient factors in the general homeostasis of NSCs. We highlight how the nutritional factors establish cross-talk between NSCs with systemic niche during CNS development via different signaling pathways. The nutrient-sensing by molecular signaling such as Insulin-PI3K-TOR are highly conserved in Drosophila and mammalian systems and play a central role in NSC fate determination and brain development. We discuss the insights from Drosophila murine and human systems to comprehend different ways through which nutrition influence NSC fate. A better understanding of the nutrition and metabolism in NSCs and their niche would assist in learning the central nervous system developmental and neurodegenerative disorders for better therapeutic design and treatment.
      PubDate: 2022-09-06
       
  • Gold catalysis in organic synthesis: fifteen years of research in India

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      Abstract: Gold catalysis has emerged as an important tool in the field of synthetic organic chemistry for the selective functionalization of C–C multiple bonds. The research in India on gold catalysis focuses on diverse fields starting from the methodology developments to the synthesis of molecular scaffolds for their potential application in medicinal chemistry and material science. Herein, we present a comprehensive overview of the gold-catalyzed organic transformations that were reported in India in the last fifteen years. Graphical abstract
      PubDate: 2022-09-05
       
  • Belousov–Zhabotinsky reaction: an open-source approach

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      Abstract: Abstract The time-dependent change in concentration of reactants in the oscillatory Belousov–Zhabotinsky reaction defined by non-linear ordinary coupled differential equations has been derived by applying normalized non-dimensional computational methods and presented graphically. The accurate normalisation procedure eschews complex mathematical steps; however, choosing the appropriate references to define the dimensionless variables necessitates a deep physical understanding of the problem. The dimensionless groups are then derived to provide the functional dependences of the unknowns of interest. Finally, to cross-check all the mentioned dependences, a computational simulation has been carried out using domain-specific to general-purpose programming languages. Although there are countless programming languages present to carry out computer simulations, a flexible, portable, and open-source language like python proves fruitful.
      PubDate: 2022-09-01
       
  • Increasing disease resistance in host plants through genome editing

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      Abstract: Abstract Diseases caused by plant pathogens pose significant challenges to crop yield and quality, thus incurring a serious constraint on the global food supply. Genome editing using the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-associated nuclease) system has revolutionized the field of biology and biotechnology. New technologies derived from CRISPR-Cas enable crop genetic improvement for plant disease resistance and the development of tools for the early detection of pathogens. This review discusses canonical and advanced genome editing tools available for understanding host–pathogen interaction and developing host resistance. We categorically cite examples of the use of genome editing technology in developing disease-resistant crops. CRISPR-Cas9 tools have enabled us to apply novel strategies to confer resistance against several plant pathogens like bacteria, viruses, fungi, and nematodes. CRISPR diagnostic methods have been developed by leveraging the CRISPR-Cas system’s precise ability to bind and cleave nucleic acids. We have also discussed the different CRISPR-diagnostic methods developed for precise and fast plant disease detection.
      PubDate: 2022-09-01
       
  • Electrochemical sensor for picric acid by using molecularly imprinted
           polymer and reduced graphene oxide modified pencil graphite electrode

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      Abstract: Abstract Here we report an electrochemical sensor for the determination of picric acid (PA) based on molecularly imprinted polymer (MIP) on reduced graphene oxide (rGO) coated pencil graphite electrode (PGE). Pyrrole (Py) was electropolymerized on the surface of rGO modified PGE, where PA was used as the template. After the extraction of PA molecules from the polymer matrix, MIP rGO PGE was obtained. Computational studies were carried out to predict the possible molecular interactions between template and polymer. The electrode modifications were characterized by various electrochemical and surface imaging techniques. The MIP rGO PGE shows linear response over PA concentration on differential pulse voltammetric (DPV) analysis with good reproducibility. MIP rGO PGE has significant mechanical stability with detection limits of 1.4 μM. The proposed sensor was applied to quantify the PA level present in the soil and water as real analytical samples successfully.
      PubDate: 2022-09-01
       
  • Hepatogenic differentiation of adipose-derived mesenchymal stem cells
           directed by topographical cues: a proof of concept study

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      Abstract: Abstract Topography and roughness are key features that can direct the behavior of cells. Here, we have developed a surface pattern comparable to the features and roughness present in the native liver tissue by virtue of the liver extracellular matrix. This study used polydimethylsiloxane to get an imprint of the topographical pattern of the native liver and used this imprint as a template to guide the differentiation of adipose-derived mesenchymal stem cells. The results showed a similar gene and protein expression profile to that of hepatocytes, showing potential in the field of scaffold development for tissue engineering applications.
      PubDate: 2022-09-01
       
  • Molecular genetic diversity of a cultivable freshwater prawn Macrobrachium
           dayanum (Henderson, 1893) from Outer Himalayas, India

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      Abstract: Abstract In the present investigation, genetic polymorphism and variability in seven natural populations of Himalayan prawn Macrobrachium dayanum were assessed by polymerase chain reaction (PCR) based two molecular techniques viz., ISSR and RAPD. Genomic DNA of each sample was isolated by Phenol–chloroform method. Genotyping by selective ISSR and RAPD markers revealed high level of genetic variability among seven populations depicted by 86.9% and 96.2% polymorphism respectively. The combined results of two molecular marker assays disclosed that populations of Nagri and Chadwal streams were genetically closest having highest values of Jaccard similarity (0.419) and Nei & Li coefficient (0.591) whereas the populations of Chadwal and Sai streams were genetically least related with lowest values of Jaccard similarity (0.206) and Nei & Li coefficient (0.342). Cluster analysis by UPGMA dendrograms revealed that seven populations of M. dayanum were distributed into two major groups which were further divided into sub-groups. The principal coordinate analysis was consistent with the UPGMA Clustering of the populations. Overall, the population of Kheri stream was found to be quite distinct from rest of six populations. The findings of present communication will serve for the sustainable conservation program of the Himalayan prawn and selection of its desired populations having higher genetic variability to withstand adverse conditions for future venture of commercial prawn culturing in the rural areas of Himalayas. In addition, the results of current study set a stage to evaluate the reasons for lesser genetic diversity of the studied species in some of the streams of Jammu and the way forward to improve the status of these lotic ecosystems to enhance the genetic polymorphism in M. dayanum.
      PubDate: 2022-09-01
       
 
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