Authors:Ziwei Cai; Shuang Fan, Xiaoyi Sun, Xiaodong Mo, Gen Yang Abstract: Relapse is the most important cause of treatment failure in acute leukemia (AL). Thus, how to predict relapse is critical for improving the survival of patients with AL. Measurable residual diseases (MRDs; previously termed minimal residual diseases), referring to the presence of remaining leukemia cells after the declaration of complete remission (CR) detected by morphological analysis, is the most important biomarker for relapse prediction.1 Several methods, including multiparameter flow cytometry (MFC), real-time quantitative polymerase chain reaction (qPCR), digital PCR (dPCR), and next-generation sequencing (NGS), are used to monitor MRD after treatment, reaching a sensitivity of 10−4 to 10−6. Citation: The Innovation 4, 3 (2023) PubDate: 2023-03-23 DOI: 10.1016/j.xinn.2023.100408 Issue No:Vol. 4, No. 3 (2023)
Authors:Yu-Qing Liu; Zheng Xiong, Yong-Lai Zhang, Hua Liu Abstract: As one of the crucial technologies of additive manufacturing (AM), projection technology, which features fast printing speed, high molding accuracy, and low cost, exhibits great potential in cutting-edge applications. The basic principle of projection-enabled AM (PAM) is the stacking of layer-wise structures, in which the dynamic mask pattern is projected onto the surface of the liquid photosensitive resin, triggering polymerization in a specific area to accomplish single-layer printing. This facilitates the layer-wise manufacture of complex three-dimensional (3D) structures. Citation: The Innovation 4, 3 (2023) PubDate: 2023-02-27 DOI: 10.1016/j.xinn.2023.100395 Issue No:Vol. 4, No. 3 (2023)