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  Subjects -> SCIENCES: COMPREHENSIVE WORKS (Total: 374 journals)
Showing 201 - 265 of 265 Journals sorted alphabetically
Jurnal MIPA     Open Access  
Jurnal Natural     Open Access  
Jurnal Sains Dasar     Open Access  
Jurnal Teknosains     Open Access  
Jurnal Udayana Mengabdi     Open Access  
Karaelmas Science and Engineering Journal     Open Access  
Karbala International Journal of Modern Science     Open Access  
Kennedy Institute of Ethics Journal     Full-text available via subscription   (Followers: 10)
LOGIKA Jurnal Ilmiah Lemlit Unswagati Cirebon     Open Access  
Logo STI Science, Technology and Innovation     Open Access   (Followers: 1)
Makara Journal of Science     Open Access  
Malawi Journal of Science and Technology     Open Access   (Followers: 6)
Maskana     Open Access  
MethodsX     Open Access   (Followers: 1)
Metode & Forskningsdesign     Open Access  
Mètode Science Studies Journal : Annual Review     Open Access  
Middle East Journal of Science     Open Access  
Middle European Scientific Bulletin     Open Access   (Followers: 3)
Modern Applied Science     Open Access   (Followers: 1)
Momona Ethiopian Journal of Science     Open Access   (Followers: 5)
MUST : Journal of Mathematics Education, Science and Technology     Open Access   (Followers: 4)
Mutis     Open Access  
National Academy Science Letters     Hybrid Journal   (Followers: 3)
National Science Review     Hybrid Journal   (Followers: 1)
Natural Sciences     Open Access  
Natural Sciences Education     Hybrid Journal  
Naturen     Full-text available via subscription  
Nepal Journal of Science and Technology     Open Access  
Network Science     Hybrid Journal   (Followers: 4)
New Directions in the Teaching of Physical Sciences     Open Access   (Followers: 2)
Nordic Journal of Science and Technology     Open Access   (Followers: 2)
Nordic Studies in Science Education     Open Access   (Followers: 3)
Nova     Open Access  
Nuncius     Hybrid Journal   (Followers: 2)
OmniScience : A Multi-disciplinary Journal     Full-text available via subscription   (Followers: 1)
Open Conference Proceedings Journal     Open Access  
Open Journal of Applied Sciences     Open Access  
Orbis Cógnita : Revista Científica     Open Access   (Followers: 2)
Patterns     Open Access   (Followers: 9)
PENDIPA : Journal of Science Education     Open Access  
People and Nature     Open Access   (Followers: 4)
Población y Desarrollo - Argonautas y caminantes     Open Access  
Politique et Sociétés     Full-text available via subscription   (Followers: 1)
Portal de la Ciencia     Open Access  
Proceedings of the Indian National Science Academy     Full-text available via subscription   (Followers: 2)
Proceedings of the Linnean Society of New South Wales     Full-text available via subscription   (Followers: 2)
Proceedings of the Royal Society of Queensland, The     Full-text available via subscription  
QScience Connect     Open Access  
Quantum Science and Technology     Hybrid Journal   (Followers: 5)
RAC: Revista Angolana de Ciências     Open Access  
Rafidain Journal of Science     Open Access  
Rehabilitation Research, Policy, and Education     Hybrid Journal   (Followers: 2)
Rekayasa     Open Access   (Followers: 1)
Reportes Científicos de la FaCEN     Open Access  
Reports in Advances of Physical Sciences     Open Access  
Research     Open Access   (Followers: 6)
Research Ideas and Outcomes     Open Access  
Research Integrity and Peer Review     Open Access  
Research Policy : X     Open Access   (Followers: 4)
Respuestas     Open Access  
Reviews in Theoretical Science     Full-text available via subscription  
Revista Bases de la Ciencia     Open Access  
Revista Binacional Brasil - Argentina: Diálogo entre as ciências     Open Access  
Revista Brasileira de Iniciação Científica     Open Access  
Revista Catarinense da Ciência Contábil     Open Access  
Revista Ciencia y Tecnología     Open Access  
Revista Ciência, Tecnologia & Ambiente     Open Access  
Revista Científica de la FAREM     Open Access  
Revista Científica de la Universidad Nacional del Este     Open Access   (Followers: 3)
Revista Cientifica Guillermo de Ockham     Open Access  
Revista Científica y Tecnológica UPSE     Open Access  
Revista Conhecimento Online     Open Access  
Revista Crítica de Ciências Sociais     Open Access  
Revista de Ciencia y Tecnología     Open Access  
Revista de Información Científica     Open Access  
Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales     Open Access  
Revista de la Sociedad Científica del Paraguay     Open Access   (Followers: 1)
Revista de la Universidad del Zulia     Open Access  
Revista Eletrônica Ludus Scientiae     Open Access  
Revista Logos Ciencia & Tecnología     Open Access  
Revista MundoFesc     Open Access  
Revista Politécnica     Open Access  
Revista Saber Digital     Open Access   (Followers: 1)
Revista Sociedad y Economía     Open Access  
Revista Tecnológica     Open Access  
Revista Theoria     Open Access   (Followers: 1)
Revista UNIMAR     Open Access  
Revista UniVap     Open Access  
Revista Vivências em Ensino de Ciências     Open Access   (Followers: 1)
Rihan Journal for Scientific Publishing     Open Access   (Followers: 1)
Royal Society Open Science     Open Access   (Followers: 7)
Ruhuna Journal of Science     Open Access  
Sainstek : Jurnal Sains dan Teknologi     Open Access  
SAINSTIS     Open Access  
Sainteknol : Jurnal Sains dan Teknologi     Open Access  
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi     Open Access  
Scholedge International Journal of Multidisciplinary & Allied Studies     Open Access  
Sci     Open Access  
Science     Full-text available via subscription   (Followers: 4814)
Science & Diplomacy     Free   (Followers: 3)
Science & Technology Studies     Open Access   (Followers: 3)
Science Advances     Free   (Followers: 37)
Science and Technology     Open Access   (Followers: 2)
Science Diliman     Open Access  
Science Heritage Journal     Open Access  
Science World Journal     Open Access  
Science, Technology and Arts Research Journal     Open Access   (Followers: 1)
ScienceRise     Open Access  
Sciences du jeu     Open Access  
Sciential     Open Access  
Scientific African     Open Access  
Scientific American     Full-text available via subscription   (Followers: 487)
Scientific American Mind     Full-text available via subscription   (Followers: 10)
Scientific Bulletin     Open Access  
Scientific Data     Open Access   (Followers: 6)
Scientific Journal of Mehmet Akif Ersoy University     Open Access  
Scientific Journal of Pure and Applied Sciences     Open Access   (Followers: 1)
Scientific Reports     Open Access   (Followers: 92)
Scientific World     Open Access  
Scientonomy : Journal for the Science of Science     Open Access   (Followers: 1)
Scienze Regionali : Italian Journal of Regional Science     Full-text available via subscription   (Followers: 18)
Selforganizology     Open Access  
Seminário de Iniciação Científica e Seminário Integrado de Ensino, Pesquisa e Extensão     Open Access  
Simbiótica     Open Access  
SINET : Ethiopian Journal of Science     Open Access   (Followers: 5)
Smart Science     Open Access  
South African Journal of Science     Open Access   (Followers: 2)
South American Sciences     Open Access  
South East European University Review (SEEU Review)     Open Access   (Followers: 3)
Springer Science Reviews     Hybrid Journal   (Followers: 2)
Studies in Science Education     Hybrid Journal   (Followers: 18)
Sultan Qaboos University Journal for Science     Open Access  
Tanzania Journal of Science     Open Access   (Followers: 4)
TD : The Journal for Transdisciplinary Research in Southern Africa     Open Access  
Technologies     Open Access   (Followers: 1)
TECNOSCIENZA: Italian Journal of Science & Technology Studies     Open Access   (Followers: 1)
Temas y Debates     Open Access  
The Innovation     Open Access   (Followers: 1)
The Scientific World Journal     Open Access  
The Social Studies     Hybrid Journal   (Followers: 3)
The Winnower     Open Access  
Theoria     Open Access   (Followers: 3)
THEORIA : An International Journal for Theory, History and Foundations of Science     Full-text available via subscription   (Followers: 1)
Transactions of Tianjin University     Full-text available via subscription  
Trilogía     Open Access  
TÜBAV Bilim Dergisi     Open Access  
Türk Bilim ve Mühendislik Dergisi     Open Access  
Tydskrif vir Geesteswetenskappe     Open Access  
Uluslararası Bilimsel Araştırmalar Dergisi (IBAD)     Open Access   (Followers: 1)
UNED Research Journal / Cuadernos de Investigación UNED     Open Access  
Uni-pluriversidad     Open Access  
Uniciencia     Open Access  
Universidad, Ciencia y Tecnología     Open Access  
Universitas (León)     Open Access  
Universitas Scientiarum     Open Access  
Unnes Science Education Journal     Open Access  
Vilnius University Proceedings     Open Access  
Walailak Journal of Science and Technology     Open Access  
WikiJournal of Science     Open Access  
World Scientific Research     Open Access  
Zeitschrift für Didaktik der Naturwissenschaften     Hybrid Journal  
Образование и наука     Open Access   (Followers: 1)
Східно-Європейський журнал передових технологій : Eastern-European Journal of Enterprise Technologies     Open Access   (Followers: 3)

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Similar Journals
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The Innovation
Number of Followers: 1  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2666-6758
Published by Elsevier Homepage  [2974 journals]
  • Cynomolgus-rhesus hybrid macaques serve as a platform for imprinting
           studies

    • Authors: Zongyang Lu; Jie Li, Yong Lu, Ling Li, Wei Wang, Chenchen Zhang, Libing Xu, Yanhong Nie, Changshan Gao, Xinyan Bian, Zhen Liu, Guang-Zhong Wang, Qiang Sun
      Abstract: Genomic imprinting can lead to allele-specific expression (ASE), where one allele is preferentially expressed more than the other. Perturbations in genomic imprinting or ASE genes have been widely observed across various neurological disorders, notably autism spectrum disorder (ASD). In this study, we crossed rhesus cynomolgus monkeys to produce hybrid monkeys and established a framework to evaluate their allele-specific gene expression patterns using the parental genomes as a reference. Our proof-of-concept analysis of the hybrid monkeys identified 353 genes with allele-biased expression in the brain, enabling us to determine the chromosomal locations of ASE clusters.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-05-02
      DOI: 10.1016/j.xinn.2023.100436
      Issue No: Vol. 4, No. 3 (2023)
       
  • China: The role of botanical gardens in conservation

    • Authors: Hongwen Huang; Peter H. Raven, Lisong Wang, Jingping Liao, Qingqing Zhan
      Abstract: Preserving as many as possible of the plants that support us directly as food, medicine, and building materials and indirectly by maintaining the conditions that make our lives sustainable will be an increasing challenge in the immediate future, owing to our population growth and the climate change that we are driving. With estimates that as many as a third of all kinds of organisms may have become extinct by the end of the century, it is clear that we must save as many of them and as much of their genetic diversity as we possibly can.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-27
      DOI: 10.1016/j.xinn.2023.100433
      Issue No: Vol. 4, No. 3 (2023)
       
  • Fluidic memristor: Bringing chemistry to neuromorphic devices

    • Authors: Tianyi Xiong; Weiqi Li, Ping Yu, Lanqun Mao
      Abstract: Neuromorphic devices, devices with resistance switch dynamic emulating the behavior of neurons, are experiencing a surge in development due to the demand for artificial intelligence and therapeutic devices such as neuroprosthetics.1 Toward reproducing the behaviors of neurons with artificial devices, neuromorphic devices based on two-terminal memristors (devices with a single-valued relationship between charge Q and magnetic flux φ, i.e., dφ = MdQ) with various mechanisms (e.g., redox, phase change, magnetic tunnelling, and ferroelectricity) have been developed for various applications, like in-memory computing or intelligent sensing.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-27
      DOI: 10.1016/j.xinn.2023.100435
      Issue No: Vol. 4, No. 3 (2023)
       
  • High-resolution observations from space to address new applications in
           hydrology

    • Authors: Luca Brocca; Wei Zhao, Hui Lu
      Abstract: There is an increasing demand from the hydrological community to improve the monitoring and modeling of hydrological processes using remote sensing technologies. However, this task has been severely limited by the coarse resolution of previous remote sensing observations. In recent years, along with the increased availability of high-resolution modeling in hydrology, the advent of high-resolution temporal dynamic satellite observations has been providing unprecedented new opportunities to address new applications and challenges in hydrology.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-27
      DOI: 10.1016/j.xinn.2023.100437
      Issue No: Vol. 4, No. 3 (2023)
       
  • Comparative analysis reveals epigenomic evolution related to species
           traits and genomic imprinting in mammals

    • Authors: Yisi Hu; Shenli Yuan, Xin Du, Jiang Liu, Wenliang Zhou, Fuwen Wei
      Abstract: DNA methylation is an epigenetic modification that plays a crucial role in various regulatory processes, including gene expression regulation, transposable element repression, and genomic imprinting. However, most studies on DNA methylation have been conducted in humans and other model species, whereas the dynamics of DNA methylation across mammals remain poorly explored, limiting our understanding of epigenomic evolution in mammals and the evolutionary impacts of conserved and lineage-specific DNA methylation.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-27
      DOI: 10.1016/j.xinn.2023.100434
      Issue No: Vol. 4, No. 3 (2023)
       
  • Complexities of the Turkey-Syria doublet earthquake sequence

    • Authors: Sidao Ni; Heping Sun, Paul Somerville, David A. Yuen, Chris Milliner, Hansheng Wang, Jiangchun Zhou, Yifei Cui
      Abstract: In the early morning of February 6th, 2023, an M7.8 earthquake occurred in southeastern Türkiye near the northern border of Syria. The event initiated a complex sequence of aftershocks, including an M7.6 earthquake about 9 h later and 90 km to the north (Figures 1A and 1B). The earthquake sequence is also referred to as a strong doublet earthquake sequence. Aftershocks of the two strong earthquakes occurred along two separate branches of the East Anatolia Fault, with lengths of up to 300 km, and some aftershocks occurred in Syria (NEIC/USGS, 2023).
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-24
      DOI: 10.1016/j.xinn.2023.100431
      Issue No: Vol. 4, No. 3 (2023)
       
  • Recent progress in the physics of twisted particles

    • Authors: Liping Zou; Pengming Zhang, Alexander J. Silenko, Liang Lu
      Abstract: Twisted (vortex) particles with intrinsic orbital angular momenta (OAMs) even in free space are of significant importance in modern physics and have important applications. Twisted photons and electrons were discovered in 1992 and 2010, respectively. The maximum observed OAMs were about 10000ℏ for photons and 1000ℏ for electrons. Recently, twisted neutrons, atoms, and molecules were also discovered. In a magnetic field, charged particles move in a helical trajectory (on a circle in the transverse plane).
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-24
      DOI: 10.1016/j.xinn.2023.100432
      Issue No: Vol. 4, No. 3 (2023)
       
  • Launching from Earth

    • Authors: Ji Dai
      Abstract: On behalf of my colleagues who conducted the study titled "Primate preoptic neurons drive hypothermia and cold defense," which was recently published in The Innovation,1 I would like to offer a response to Cerri et al.'s commentary on our study in a correspondence.2
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-22
      DOI: 10.1016/j.xinn.2023.100430
      Issue No: Vol. 4, No. 3 (2023)
       
  • Back to Earth

    • Authors: Matteo Cerri; Jürgen Bereiter-Hahn, Gerhard Heldmaier, Alexander Choukér, Leopold Summerer
      Abstract: On behalf of the Topical Team Hibernation of the European Space Agency, we would like to provide some comments on the recently published article "Primate preoptic neurons drive hypothermia and cold defense" by Zhang and colleagues.1
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-22
      DOI: 10.1016/j.xinn.2023.100429
      Issue No: Vol. 4, No. 3 (2023)
       
  • JWST’s eyes on an alien world

    • Authors: Xi Zhang
      Abstract: Our galaxy is believed to have more than a hundred billion planets, with over 5,000 of them discovered so far. Of these, only around 50 have unveiled their composition beyond the most prevalent hydrogen and helium. Why is it so difficult' Unlike the exploration of planets within our Solar System where we can send probes to gather samples, studying exoplanets is more akin to wine tasting—we must rely on our sense of smell. Remote sensing is currently the only approach available for characterizing exoplanets.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-21
      DOI: 10.1016/j.xinn.2023.100428
      Issue No: Vol. 4, No. 3 (2023)
       
  • Projecting universal health risks under climate change to bridge
           mitigation and health adaptation objectives

    • Authors: Tiantian Li; Can Zhang, Jie Ban, Peng Du, Runmei Ma, Patrick L. Kinney
      Abstract: Climate change is one of the biggest threats facing humanity. The global community has stated the objective of limiting the increase in the global average temperature to 1.5°C to prevent potentially catastrophic effects and health threats. A key strategy to reach the mitigation objective is to achieve carbon neutrality, also termed net zero, by cutting down emissions of greenhouse gases to as nearly zero level as possible by the mid-century, mainly through the implementation of clean energy policies or the increase in carbon sinks.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-12
      DOI: 10.1016/j.xinn.2023.100427
      Issue No: Vol. 4, No. 3 (2023)
       
  • Rapid, artifact-reduced, image reconstruction for super-resolution
           structured illumination microscopy

    • Authors: Zhaojun Wang; Tianyu Zhao, Yanan Cai, Jingxiang Zhang, Huiwen Hao, Yansheng Liang, Shaowei Wang, Yujie Sun, Tongsheng Chen, Piero R. Bianco, Kwangsung Oh, Ming Lei
      Abstract: Super-resolution structured illumination microscopy (SR-SIM) is finding increasing application in biomedical research due to its superior ability to visualize subcellular dynamics in living cells. However, during image reconstruction artifacts can be introduced and when coupled with time-consuming postprocessing procedures, limits this technique from becoming a routine imaging tool for biologists. To address these issues, an accelerated, artifact-reduced reconstruction algorithm termed joint space frequency reconstruction-based artifact reduction algorithm (JSFR-AR-SIM) was developed by integrating a high-speed reconstruction framework with a high-fidelity optimization approach designed to suppress the sidelobe artifact.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-12
      DOI: 10.1016/j.xinn.2023.100425
      Issue No: Vol. 4, No. 3 (2023)
       
  • Benefit analysis of multi-approach biomass energy utilization toward
           carbon neutrality

    • Authors: Jiaoyue Wang; Jingying Fu, Zhitong Zhao, Longfei Bing, Fengming Xi, Feng Wang, Jiang Dong, Shiyun Wang, Gang Lin, Yan Yin, Qinqin Hu
      Abstract: To reduce greenhouse gas (GHG) emissions, biomass has been increasingly developed as a renewable and clean alternative to fossil fuels because of its carbon-neutral characteristics. China has been investigating the rational development and use of bioenergy for developing its clean energy and achieving carbon neutrality. Substituting fossil fuels with multi-source and multi-approach utilized bioenergy and corresponding carbon reduction in China remain largely unexplored. Here, a comprehensive bioenergy accounting model with a multi-dimensional analysis was developed by combining spatial, life cycle, and multi-path analyses.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-12
      DOI: 10.1016/j.xinn.2023.100423
      Issue No: Vol. 4, No. 3 (2023)
       
  • Etoposide, dexamethasone, and pegaspargase with sandwiched radiotherapy in
           early-stage natural killer/T-cell lymphoma: A randomized phase III study

    • Authors: Huijuan Zhong; Shu Cheng, Xi Zhang, Bing Xu, Jiayi Chen, Xufeng Jiang, Jie Xiong, Yu Hu, Guohui Cui, Juying Wei, Wenbin Qian, Xiaobing Huang, Ming Hou, Feng Yan, Xin Wang, Yongping Song, Jianda Hu, Yuanhua Liu, Xuejun Ma, Fei Li, Chongyang Wu, Junmin Chen, Li Yu, Ou Bai, Jingyan Xu, Zunmin Zhu, Li Liu, Xin Zhou, Li Huang, Yin Tong, Ting Niu, Depei Wu, Hao Zhang, Chaofu Wang, Binshen Ouyang, Hongmei Yi, Qi Song, Gang Cai, Biao Li, Jia Liu, Zhifeng Li, Rong Xiao, Luqun Wang, Yujie Jiang, Yanyan Liu, Xiaoyun Zheng, Pengpeng Xu, Hengye Huang, Li Wang, Saijuan Chen, Weili Zhao
      Abstract: Methotrexate, etoposide, dexamethasone, and pegaspargase (MESA) with sandwiched radiotherapy is known to be effective for early-stage extranodal natural killer/T-cell lymphoma, nasal type (NKTCL). We explored the efficacy and safety of reduced-intensity, non-intravenous etoposide, dexamethasone, and pegaspargase (ESA) with sandwiched radiotherapy. This multicenter, randomized, phase III trial enrolled patients aged between 14 and 70 years with newly diagnosed early-stage nasal NKTCL from 27 centers in China.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-12
      DOI: 10.1016/j.xinn.2023.100426
      Issue No: Vol. 4, No. 3 (2023)
       
  • Optimizing protected areas to boost the conservation of key protected
           wildlife in China

    • Authors: Chunrong Mi; Kai Song, Liang Ma, Jiliang Xu, Baojun Sun, Yuehua Sun, Jianguo Liu, Weiguo Du
      Abstract: To meet the challenge of biodiversity loss and reach the targets of the proposed Post-2020 Global Biodiversity Framework, the Chinese government updated the list of national key protected wildlife in 2021 and has been continually expanding the protected areas (PAs). However, the status of protected wildlife in PAs remains unclear. In this study, we conducted a national assessment of the status of protected wildlife and suggested an optimization plan to overcome these shortcomings. From 1988 to 2021, the number of protected species almost doubled, and the area of PAs increased by 2.4 times, covering over 92.8% of the protected species.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-11
      DOI: 10.1016/j.xinn.2023.100424
      Issue No: Vol. 4, No. 3 (2023)
       
  • Targeted protein degradation bypassing cereblon and von Hippel-Lindau

    • Authors: Wenchao Lu
      Abstract: Targeted protein degradation (TPD) has emerged as a new drug discovery approach to wipe out disease-causing proteins by harnessing the ubiquitin-proteasome system (UPS). A major class of molecules in the field are called proteolysis-targeting chimeras (PROTACs), which are heterobifunctional molecules encompassing two ligands that bind to a protein of interest and the E3 ligase, respectively joint by a linker.1 Due to its catalytic mechanism that enables event-driven pharmacology, PROTACs technology can induce an efficient degradation and therefore achieve the pharmacology at a lower dose compared with traditional small molecule inhibitors that exert their inhibition through an occupancy-driven mechanism.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-10
      DOI: 10.1016/j.xinn.2023.100422
      Issue No: Vol. 4, No. 3 (2023)
       
  • Ultrasound-responsive matters for biomedical applications

    • Authors: Danqing Huang; Jinglin Wang, Chuanhui Song, Yuanjin Zhao
      Abstract: Ultrasound (US) is a biofavorable mechanical wave that has shown practical significance in biomedical fields. Due to the cavitation effect, sonoluminescence, sonoporation, pyrolysis, and other biophysical and chemical effects, a wide range of matters have been elucidated to be responsive to the stimulus of US. This review addresses and discusses current developments in US-responsive matters, including US-breakable intermolecular conjugations, US-catalytic sonosensitizers, fluorocarbon compounds, microbubbles, and US-propelled micro- and nanorobots.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-04-06
      DOI: 10.1016/j.xinn.2023.100421
      Issue No: Vol. 4, No. 3 (2023)
       
  • Space technology: A powerful tool for safeguarding world heritage

    • Authors: Lei Luo; Jie Liu, Francesca Cigna, Damian Evans, Mario Hernandez, Deodato Tapete, Peter Shadie, Athos Agapiou, Abdelaziz Elfadaly, Min Chen, Lanwei Zhu, Bihong Fu, Ruixia Yang, Shahina Tariq, Mohamed Ouessar, Rosa Lasaponara, Xinyuan Wang, Huadong Guo
      Abstract: The Convention Concerning the Protection of the World Cultural and Natural Heritage (WHC), adopted by United Nations Educational, Scientific and Cultural Organization (UNESCO) on November 16, 1972, aims to ensure the identification, protection, conservation, presentation, and transmission to future generations of the world’s cultural and natural heritage. The WHC works toward these goals by emphasizing the Outstanding Universal Value (OUV) of heritage sites and the unique contribution such places can make to conservation and human development agendas.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-03-28
      DOI: 10.1016/j.xinn.2023.100420
      Issue No: Vol. 4, No. 3 (2023)
       
  • Assessing changes in nighttime lighting in the aftermath of the
           Turkey-Syria earthquake using SDGSAT-1 satellite data

    • Authors: Bo Yu; Fang Chen, Ning Wang, Lei Wang, Huadong Guo
      Abstract: On February 6, 2023, a powerful earthquake with a magnitude of 7.8 MW struck southeastern Turkey and northwestern Syria. The epicenter of the earthquake was in Gaziantep, Turkey. The earthquake was followed by a devastating aftershock 9 h later, which registered a magnitude of 7.5 MW and which had an epicenter located 100 km farther north in Kahramanmaras, Turkey. Thousands of subsequent tremors and aftershocks since the initial earthquake have further exacerbated the impacts on lives and infrastructure, resulting in more than 50,000 deaths and damage to hundreds of thousands of buildings in the region.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-03-23
      DOI: 10.1016/j.xinn.2023.100419
      Issue No: Vol. 4, No. 3 (2023)
       
  • Novel microfluidic device for measurable residual disease detection in
           acute leukemia

    • Authors: Ziwei Cai; Shuang Fan, Xiaoyi Sun, Xiaodong Mo, Gen Yang
      Abstract: Relapse is the most important cause of treatment failure in acute leukemia (AL). Thus, how to predict relapse is critical for improving the survival of patients with AL. Measurable residual diseases (MRDs; previously termed minimal residual diseases), referring to the presence of remaining leukemia cells after the declaration of complete remission (CR) detected by morphological analysis, is the most important biomarker for relapse prediction.1 Several methods, including multiparameter flow cytometry (MFC), real-time quantitative polymerase chain reaction (qPCR), digital PCR (dPCR), and next-generation sequencing (NGS), are used to monitor MRD after treatment, reaching a sensitivity of 10−4 to 10−6.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-03-23
      DOI: 10.1016/j.xinn.2023.100408
      Issue No: Vol. 4, No. 3 (2023)
       
  • Save the life-sustaining mattic layer on the Qinghai-Tibetan Plateau

    • Authors: Ganlin Zhang; Fei Yang, Hao Long
      Abstract: The Kobresia pastures on the Qinghai-Tibetan Plateau (QTP) are a key feature of the world’s largest alpine ecosystem. They occupy approximately 450,000 km2, nearly 1/5 of the area of the QTP, and dominate the headwaters of most of Asia’s great rivers (Figure 1).1 Kobresia plants are typically only a few centimeters tall and form a fairly firm turf blanketing all relief positions wherever the environment allows. The Kobresia roots are interwoven with the surface soil. This characteristic layer is called a “mattic epipedon—a mat-like surface soil layer,” according to Chinese soil taxonomy.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-03-21
      DOI: 10.1016/j.xinn.2023.100418
      Issue No: Vol. 4, No. 3 (2023)
       
  • Evolution of the Yangtze River and its biodiversity

    • Authors: Feng Chen; Ge Xue, Yeke Wang, Hucai Zhang, Peter D. Clift, Yaowu Xing, Jun He, James S. Albert, Jun Chen, Ping Xie
      Abstract: Documenting the origins of megadiverse (sub)tropical aquatic ecosystems is an important goal for studies of evolution and ecology. Nonetheless, the geological and ecological establishment of the modern Yangtze River remains poorly understood. Here, we reconstruct the geographic and ecological history of an endemic clade of East Asian fishes based on the mitochondrial phylogenomics analysis of Cyprinidae using 15 fossil calibrations. We estimate an ancestral condition of benthic spawning with demersal or adhesive eggs in southern East Asia before ∼23 Ma and a derived condition of riverine spawning with semibuoyant eggs in the Yangtze by ∼18 Ma.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-03-21
      DOI: 10.1016/j.xinn.2023.100417
      Issue No: Vol. 4, No. 3 (2023)
       
  • Targeted protein degradation in cancers: Orthodox PROTACs and beyond

    • Authors: Jin Li; Xinxin Chen, Aiping Lu, Chao Liang
      Abstract: Targeted protein degradation (TPD) is emerging as a strategy to overcome the limitations of traditional small-molecule inhibitors. Proteolysis-targeting chimera (PROTAC) technology can be used to target proteins by hijacking the ubiquitin-proteasome system. Conceptually, PROTAC aims to target the “undruggable” majority of proteins in the human proteome. Through constant exploration and optimization of PROTACs and the exploitation of other TPD strategies over two decades, TPD has expanded from theoretical studies to clinical strategies, with practical applications in oncological, immunological, and other diseases.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-03-15
      DOI: 10.1016/j.xinn.2023.100413
      Issue No: Vol. 4, No. 3 (2023)
       
  • Breakthroughs in projection-enabled additive manufacturing: From novel
           strategies to cutting-edge applications

    • Authors: Yu-Qing Liu; Zheng Xiong, Yong-Lai Zhang, Hua Liu
      Abstract: As one of the crucial technologies of additive manufacturing (AM), projection technology, which features fast printing speed, high molding accuracy, and low cost, exhibits great potential in cutting-edge applications. The basic principle of projection-enabled AM (PAM) is the stacking of layer-wise structures, in which the dynamic mask pattern is projected onto the surface of the liquid photosensitive resin, triggering polymerization in a specific area to accomplish single-layer printing. This facilitates the layer-wise manufacture of complex three-dimensional (3D) structures.
      Citation: The Innovation 4, 3 (2023)
      PubDate: 2023-02-27
      DOI: 10.1016/j.xinn.2023.100395
      Issue No: Vol. 4, No. 3 (2023)
       
 
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