JournalTOCs

iScience
Number of Followers: 2

This is an Open Access Journal

Open Access journal
ISSN (Online) 2589-0042
Published by Elsevier

[2974 journals]

China’s multi-sector-shared CCUS networks in a carbon-neutral vision
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Haotian Tang, Wenying Chen, Shu Zhang, Qianzhi Zhang
Statistical mechanics of biomolecular condensates via cavity methods
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Nino Lauber, Ondrej Tichacek, Rudrarup Bose, Christoph Flamm, Luca Leuzzi, T-Y Dora Tang, Kepa Ruiz-Mirazo, Daniele De Martino
Visual and circadian regulation of Drosophila BDBT and BDBT effects on DBT
and PER localization
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Richard Brent Nolan, Colleen Bontrager, Abigail Bowser, Alyssa Corley, Hana Fiedler, Connor Flathers, Lauren Francis, Angel Le, Seyyed Mahmoudjafari, Tinh Nim, Connor E. Muolo, Brianna Shores, Christopher Viermann, Adam Waldren, Carmen Zatezalo, Jin-Yuan Fan, Jeffrey L. Price
Alterations in oligodendrocyte transcriptional networks reveal
region-specific vulnerabilities to neurological disease
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Dario Tommasini, Rachel Fox, Kathie J. Ngo, Jason D. Hinman, Brent L. Fogel
MicroRNAs emerging coordinate with placental mammals alter pathways in
endometrial epithelia important for endometrial function
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Laura Hume, Jessica C. Edge, Haidee Tinning, Dapeng T. Wang, Alysha S. Taylor, Vladimir Ovchinnikov, Annika V. Geijer-Simpson, Pavle Vrljicak, Jan J. Brosens, Emma S. Lucas, Nigel A.B. Simpson, Jayne Shillito, Karen Forbes, Mary J. O’Connell, Niamh Forde
Rosiglitazone reduces diabetes angiopathy by inhibiting mitochondrial
dysfunction dependent on regulating HSP22 expression
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Lingling Yu, Shengsong Chen, Qian Liang, Chahua Huang, Weifang Zhang, Longlong Hu, Yun Yu, Liang Liu, Xiaoshu Cheng, Huihui Bao
Long-range connectome of pyramidal neurons in the sensorimotor cortex
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Mei Yao, Ayizuohere Tudi, Tao Jiang, Xu An, Qingtao Sun, Anan Li, Z. Josh Huang, Hui Gong, Xiangning Li
Development of diverse adjustable axially chiral biphenyl ligands and
catalysts
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Jiyang Jie, Haijun Yang, Yufen Zhao, Hua Fu
EtcPRS Mut as a molecular marker of halofuginone resistance in Eimeria
tenella and Toxoplasma gondii
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Pei Sun, Yuanyuan Zhang, Chaoyue Wang, Dandan Hu, Jie Liu, Linlin Chen, Fangyun Shi, Xinming Tang, Zhenkai Hao, Jingxia Suo, Yonglan Yu, Xun Suo, Xianyong Liu
Tissue-specific heteroplasmy segregation is accompanied by a sharp mtDNA
decline in Caenorhabditis elegans soma
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Nikita Tsyba, Gaomin Feng, Lantana K. Grub, James P. Held, Adrianna M. Strozak, Kristopher Burkewitz, Maulik R. Patel
Suppression of preadipocyte determination by SOX4 limits white adipocyte
hyperplasia in obesity
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Ting He, Shuai Wang, Shengnan Li, Huanming Shen, Lingfeng Hou, Yunjia Liu, Yixin Wei, Fuan Xie, Zhiming Zhang, Zehang Zhao, Chunli Mo, Huiling Guo, Qingsong Huang, Rui Zhang, Dongyan Shen, Boan Li
Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver
disease in high-fat diet-induced obese mice
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Min Wang, Lili Li, Jun Qian, Nannan Wang, Jun Bao, Jiangyue Lu, Faming Chen, Yanfen Li, Yangheng Zhang, Fuhua Yan
Pain-related neuronal ensembles in the primary somatosensory cortex
contribute to hyperalgesia and anxiety
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Tatsuya Ishikawa, Koshi Murata, Hiroaki Okuda, Ilia Potapenko, Kiyomi Hori, Takafumi Furuyama, Ryo Yamamoto, Munenori Ono, Nobuo Kato, Yugo Fukazawa, Noriyuki Ozaki
Synaptic scaling of corticostriatal circuits underlies hyperactivity in
GABA Transporter-1 deficient mice
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Yan-Jiao Wu, Xin Yi, Xue Gu, Qi Wang, Qin Jiang, Ying Li, Michael X. Zhu, Jianqing Ding, Wei-Guang Li, Tian-Le Xu
Changes in serum-neutralizing antibody potency and breadth post-SARS-CoV-2
mRNA vaccine boost
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Manoj S. Nair, Ruy M. Ribeiro, Maple Wang, Anthony D. Bowen, Lihong Liu, Yicheng Guo, Jennifer Y. Chang, Pengfei Wang, Zizhang Sheng, Magdalena E. Sobieszczyk, Alan S. Perelson, Yaoxing Huang, David D. Ho
Temporal dynamics of TNF-mediated changes in hematopoietic stem cell
function and recovery
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Alexandra Rundberg Nilsson, Isabel Hidalgo, David Bryder, Cornelis Jan Pronk
Neural and central mechanisms of kidney fibrosis after relief of ureteral
obstruction
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Huanjuan Su, Zhichen Yang, Ying Zhang, Bihui Yang, Zhanmei Zhou, Cailing Su, Wei Cao
Pseudotime dynamics of T cells in pancreatic ductal adenocarcinoma inform
distinct functional states within the regulatory and cytotoxic T cells
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Ashwin Jainarayanan, Nithishwer Mouroug-Anand, Edward H. Arbe-Barnes, Adam J. Bush, Rachael Bashford-Rogers, Adam Frampton, Lara Heij, Mark Middleton, Michael L. Dustin, Enas Abu-Shah, Shivan Sivakumar
Selective dysfunction of fast-spiking inhibitory interneurons and
disruption of perineuronal nets in a tauopathy mouse model
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Takehiro Kudo, Hiroyuki Takuwa, Manami Takahashi, Takuya Urushihata, Masafumi Shimojo, Kazuaki Sampei, Mitsugu Yamanaka, Yutaka Tomita, Naruhiko Sahara, Tetsuya Suhara, Makoto Higuchi
Controllable self-replicating RNA vaccine delivered intradermally elicits
predominantly cellular immunity
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Tomokazu Amano, Hong Yu, Misa Amano, Erica Leyder, Maria Badiola, Priyanka Ray, Jiyoung Kim, Akihiro C. Ko, Achouak Achour, Nan-ping Weng, Efrat Kochba, Yotam Levin, Minoru S.H. Ko
Preclinical safety and efficacy of a therapeutic antibody that targets
SARS-CoV-2 at the sotrovimab face but is escaped by Omicron
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Jakob Kreye, S. Momsen Reincke, Stefan Edelburg, Lara M. Jeworowski, Hans-Christian Kornau, Jakob Trimpert, Peter Hombach, Sophia Halbe, Volker Nölle, Martin Meyer, Stefanie Kattenbach, Elisa Sánchez-Sendin, Marie L. Schmidt, Tatjana Schwarz, Ruben Rose, Andi Krumbholz, Sophie Merz, Julia M. Adler, Kathrin Eschke, Azza Abdelgawad
Single-cell sequencing reveals peritoneal environment and insights into
fibrosis in CAPD patients
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Wenxue Hu, Guanglan Li, Wei Dong, Peng He, Wei Liu, Yanhua Wu, Huaban Liang, Feng Wen, Feng Yu, Yan Yin, Zhiming Ye, Wenke Hao, Xinling Liang
Multi-omics analysis reveals underlying host responses in pediatric
respiratory syncytial virus pneumonia
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Xiaolan Huang, Fang Li, Yi Wang, Xinbei Jia, Nan Jia, Fei Xiao, Chunrong Sun, Jin Fu, Min Chen, Xiaodai Cui, Dong Qu, Laurence Don Wai Luu, Jun Tai, Jieqiong Li
Additional mutations based on Omicron BA.2.75 mediate its further evasion
from broadly neutralizing antibodies
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Huimin Guo, Jie Jiang, Senlin Shen, Xiangyang Ge, Qing Fan, Bing Zhou, Lin Cheng, Bin Ju, Zheng Zhang
An AKT1-and TRIM21-mediated phosphodegron controls proteasomal degradation
of HuR enabling cell survival under heat shock
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Sharanya Nag, Sayanur Rahaman, Abhishek Guha, Partho Sarothi Ray
Mathematical modeling and biochemical analysis support partially ordered
calmodulin-myosin light chain kinase binding
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Melissa J.S. MacEwen, Domnita-Valeria Rusnac, Henok Ermias, Timothy M. Locke, Hayden E. Gizinski, Joseph P. Dexter, Yasemin Sancak
Mitochondria-associated membrane protein PACS2 maintains right cardiac
function in hypobaric hypoxia
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Jie Yang, Mengjia Sun, Renzheng Chen, Xiaowei Ye, Boji Wu, Zhen Liu, Jihang Zhang, Xubin Gao, Ran Cheng, Chunyan He, Jingyu He, Xuhong Wang, Lan Huang
Boolean modeling of mechanosensitive epithelial to mesenchymal transition
and its reversal
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Emmalee Sullivan, Marlayna Harris, Arnav Bhatnagar, Eric Guberman, Ian Zonfa, Erzsébet Ravasz Regan
Assessing the impact of carbon dioxide removal on the power system
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Augustin Prado, Solene Chiquier, Mathilde Fajardy, Niall Mac Dowell
FDA-approved Abl/EGFR/PDGFR kinase inhibitors show potent efficacy against
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Robert Meineke, Sonja Stelz, Maximilian Busch, Christopher Werlein, Mark Kühnel, Danny Jonigk, Guus F. Rimmelzwaan, Husni Elbahesh
Trigging stepwise-strand displacement amplification lights up numerous
G-quadruplex for colorimetric signaling of serum microRNAs
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Huo Xu, Fenglin Yang, Danlong Chen, Weilin Ye, Guohui Xue, Lee Jia
NLRC5 affects diet-induced adiposity in female mice and co-regulates
peroxisome proliferator-activated receptor PPARγ target genes
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Sarah Bauer, Vanessa Aeissen, Alena M. Bubeck, Ioannis Kienes, Kornelia Ellwanger, Mona Scheurenbrand, Fjolla Rexhepi, Sheela Ramanathan, Philip Rosenstiel, W. Florian Fricke, Thomas A. Kufer
Identification of actionable targets for breast cancer intervention using
a diversity outbred mouse model
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Jennifer B. Jacob, Kuang-Chung Wei, Gerold Bepler, Joyce D. Reyes, Andi Cani, Lisa Polin, Kathryn White, Seongho Kim, Nerissa Viola, Julie McGrath, Anthony Guastella, CongCong Yin, Qing-Shen Mi, Benjamin L. Kidder, Kay-Uwe Wagner, Stuart Ratner, Victoria Phillips, Joanne Xiu, Prahlad Parajuli, Wei-Zen Wei
Development of an in vivo system to model breast cancer metastatic
organotropism and evaluate treatment response using the chick embryo
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Sumreen Javed, Sepideh Soukhtehzari, Nikki Salmond, Nazarine Fernandes, Karla C. Williams
Strain engineering of high-entropy alloy catalysts for electrocatalytic
water splitting
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Bing Wang, Weigui Liu, Yecheng Leng, Xiwen Yu, Cheng Wang, Lianghe Hu, Xi Zhu, Congping Wu, Yingfang Yao, Zhigang Zou
Noradrenergic pathway from the locus coeruleus to heart is implicated in
modulating SUDEP
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): XiTing Lian, Qing Xu, YuLing Wang, LeYuan Gu, Qian Yu, WeiHui Shao, HaiXiang Ma, Yue Shen, Lu Liu, JiaXuan Gu, HongHai Zhang
A generalized non-linear model predicting efficacy of neoadjuvant therapy
in HER2+ breast cancer
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Yusong Wang, Xiaoyan Liu, Keda Yu, Shouping Xu, Pengfei Qiu, Xinwen Zhang, Mozhi Wang, Yingying Xu
The state of macro-energy systems research: Common critiques, current
progress, and research priorities
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Rachel Moglen, Kiran Prakash Chawla, Patricia Levi, Yinong Sun, Oladoyin Phillips, Benjamin D. Leibowicz, Jesse D. Jenkins, Emily A. Grubert
Advances in self-assembled Au-DNA nanomachines
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Qianying Zhang, Shengshi Xu, Jingyi Zheng, Jian-Rong Zhang, Jun-Jie Zhu
Role of exosomal ncRNAs released by M2 macrophages in tumor progression of
gastrointestinal cancers
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Abdo Meyiah, Murad Alahdal, Eyad Elkord
Coronavirus accessory protein ORF3 biology and its contribution to viral
behavior and pathogenesis
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Fusheng Si, Shuai Song, Ruisong Yu, Zhen Li, Wenqiang Wei, Chao Wu
Accelerating Ammonia Synthesis in a Membraneless Flow Electrolyzer through
Coupling Ambient Dinitrogen Oxidation and Water Splitting
- Abstract: Publication date: Available online 21 March 2023Source: iScienceAuthor(s): Jing-Jing Lv, Zhe Li, Jiaju Fu, Wenlei Zhu
Title: Biomedical Discovery through the integrative Biomedical Knowledge
Hub (iBKH)
- Abstract: Publication date: Available online 21 March 2023Source: iScienceAuthor(s): Chang Su, Yu Hou, Manqi Zhou, Suraj Rajendran, Jacqueline R.M.A. Maasch, Zehra Abedi, Haotan Zhang, Zilong Bai, Anthony Cuturrufo, Winston Guo, Fayzan F. Chaudhry, Gregory Ghahramani, Jian Tang, Feixiong Cheng, Yue Li, Rui Zhang, Steven T DeKosky, Jiang Bian, Fei Wang
Importance of cooperation: how host nest defenses effectively prevent
brood parasitism from the cuckoos
- Abstract: Publication date: Available online 21 March 2023Source: iScienceAuthor(s): Longwu Wang, Huahua Zhao, Haixia Luo, Gangbin He, Hanlin Yan, Wei Liang
Crabtree effect in kidney proximal tubule cells via late-stage glycolytic
intermediates
- Abstract: Publication date: Available online 21 March 2023Source: iScienceAuthor(s): Manjula Darshi, Jana Tumova, Afaf Saliba, Jiwan Kim, Judy Baek, Subramaniam Pennathur, Kumar Sharma
CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for
CAR-T design in solid malignancies
- Abstract: Publication date: Available online 21 March 2023Source: iScienceAuthor(s): Thu Le Trinh, William A. Adams, Alexandra Calescibetta, Nhan Tu, Robert Dalton, Tina So, Max Wei, Grace Ward, Elena Kostenko, Sean Christiansen, Ling Cen, Amy McLemore, Kayla Reed, Junmin Whitting, Danielle Gilvary, Neale Lopez Blanco, Carlos Moran Segura, Jonathan Nguyen, Wendy Kandell, Xianghong Chen
Mitochondria hormesis delays aging and associated diseases in C. elegans
impacting on key ferroptosis players
- Abstract: Publication date: Available online 21 March 2023Source: iScienceAuthor(s): Alfonso Schiavi, Eva Salveridou, Vanessa Brinkmann, Anjumara Shaik, Ralph Menzel, Sumana Kalyanasundaram, Ståle Nygård, Hilde Nilsen, Natascia Ventura
The CIDNet model compared favourably with expert radiologists Development
and evaluation of an artificial intelligence system for children
intussusception diagnosis using ultrasound images
- Abstract: Publication date: Available online 21 March 2023Source: iScienceAuthor(s): Xiong Chen, Guochang You, Qinchang Chen, Xiangxiang Zhang, Na Wang, Xuehua He, Liling Zhu, Zhouzhou Li, Chen Liu, Shixiang Yao, Junshuang Ge, Wenjing Gao, Hongkui Yu
Title: Bat vocal sequences enhance contextual information independently of
syllable order
- Abstract: Publication date: Available online 21 March 2023Source: iScienceAuthor(s): Y. Amit, Y. Yovel
Adiponectin-mediated promotion of CD44 suppresses diabetic vascular
inflammatory effects
- Abstract: Publication date: Available online 20 March 2023Source: iScienceAuthor(s): Yanru Duan, Shihan Zhang, Yuanyuan Xing, Ye Wu, Wen Zhao, Pinxue Xie, Huina Zhang, Xinxiao Gao, Yanwen Qin, Yajing Wang, Xinliang Ma, Yunhui Du, Huirong Liu
Main Manuscript for Accelerated cropland expansion into high integrity
forests and protected areas globally in the 21st century
- Abstract: Publication date: Available online 20 March 2023Source: iScienceAuthor(s): Lanhui Wang, Fangli Wei, Jens-Christian Svenning
Impact of hybrid immunity booster vaccination and Omicron breakthrough
infection on SARS-CoV-2 VOCs cross-neutralization
- Abstract: Publication date: Available online 20 March 2023Source: iScienceAuthor(s): Edwards Pradenas, Silvia Marfil, Víctor Urrea, Macedonia Trigueros, Tetyana Pidkova, Anna Pons-Grífols, Raquel Ortiz, Carla Rovirosa, Ferran Tarrés-Freixas, Carmen Aguilar-Gurrieri, Ruth Toledo, Anna Chamorro, Marc Noguera-Julian, Lourdes Mateu, Ignacio Blanco, Eulàlia Grau, Marta Massanella, Jorge Carrillo, Bonaventura Clotet, Benjamin Trinité
Sensory detection of female olfactory cues as a central regulator of
energy metabolism and body weight in male mice
- Abstract: Publication date: Available online 20 March 2023Source: iScienceAuthor(s): Michael Garratt, Christine Neyt, Sharon R Ladyman, Martina Pyrski, Frank Zufall, Trese Leinders-Zufall
Steroidogenic factor 1 protects mice from obesity-induced glucose
intolerance via improving glucose-stimulated insulin secretion by beta
cells
- Abstract: Publication date: Available online 20 March 2023Source: iScienceAuthor(s): Yan Guo, Liehua Liu, Yanglei Cheng, Hai Li, Xuesi Wan, Jiajing Ma, Juan Liu, Weiwei Liang, Pengyuan Zhang, Jie Chen, Xiaopei Cao, Hongyu Guan, Haipeng Xiao, Yanbing Li
Biocatalytic potential of Pseudolycoriella CAZymes (Sciaroidea, Diptera)
in degrading plant and fungal cell wall polysaccharides
- Abstract: Publication date: Available online 20 March 2023Source: iScienceAuthor(s): Vitor Trinca, Sibeli Carli, João Vitor Cardoso Uliana, Carolina Victal Garbelotti, Mariana Mendes da Silva, Vitor Kunes, Luana Parras Meleiro, Guilherme Thomaz Pereira Brancini, Frank Menzel, Luiz Paulo Moura Andrioli, Tatiana Teixeira Torres, Richard John Ward, Nadia Monesi
High-Resolution Confocal and Light-Sheet Imaging of Collagen 3D Network
Architecture in Very Large Samples
- Abstract: Publication date: Available online 20 March 2023Source: iScienceAuthor(s): Grigorii Timin, Michel C. Milinkovitch
Impavido attenuates inflammation, reduces atherosclerosis, and alters gut
microbiota in hyperlipidemic mice.
- Abstract: Publication date: Available online 20 March 2023Source: iScienceAuthor(s): C. Alicia Traughber, Amanda J Iacano, Kalash Neupane, Mariam R Khan, Emmanuel Opoku, Tina Nunn, Ashutosh Prince, Naseer Sangwan, Stanley L Hazen, Jonathan D Smith, Kailash Gulshan
Thermal conductivity across transition metal dichalcogenide bilayers
- Abstract: Publication date: Available online 18 March 2023Source: iScienceAuthor(s): Insa F. de Vries, Helena Osthues, Nikos L. Doltsinis
Predicting peritoneal recurrence in gastric cancer with serosal invasion
using a pathomics nomogram
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Dexin Chen, Jianbo Lai, Jiaxin Cheng, Meiting Fu, Liyan Lin, Feng Chen, Rong Huang, Jun Chen, Jianping Lu, Yuning Chen, Guangyao Huang, Miaojia Yan, Xiaodan Ma, Guoxin Li, Gang Chen, Jun Yan
UPL5 modulates WHY2 protein distribution in a Kub-site dependent
ubiquitination in response to [Ca2+]cyt-induced leaf senescence
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Wei Lan, Weibo Ma, Shuai Zheng, Ping Yang, Yuhao Qiu, Wenfang Lin, Yujun Ren, Ying Miao
Conspiracy spillovers and geoengineering
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Ramit Debnath, David M. Reiner, Benjamin K. Sovacool, Finn Müller-Hansen, Tim Repke, R. Michael Alvarez, Shaun D. Fitzgerald
High yield with efficient nutrient use: Opportunities and challenges for
wheat
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Ning Huang, Haiyan Dang, Wenyan Mu, Jianxiong Ma, Yue Ma, Li Wang, Mei Shi, Hui Tian, Jinshan Liu, Yinglong Chen, Zhaohui Wang
Biased pollen transfer by bumblebees favors the paternity of
virus-infected plants in cross-pollination
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Alex M. Murphy, Sanjie Jiang, James A.D. Elderfield, Adrienne E. Pate, Chay Halliwell, Beverley J. Glover, Nik J. Cunniffe, John P. Carr
Asymmetric [2+1] cycloaddition of difluoroalkyl-substituted carbenes with
alkenes under rhodium catalysis: Synthesis of chiral
difluoroalkyl-substituted cyclopropanes
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Xinyu Zhang, Yongquan Ning, Chunqi Tian, Giuseppe Zanoni, Xihe Bi
A crack compensation strategy for highly stretchable conductors based on
liquid metal inclusions
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Guoqiang Li, Xing Ma, Zirong Xu, Yifeng Shen, Man Yuan, Jianping Huang, Tim Cole, Jingjing Wei, Sanhu Liu, Fei Han, Hanfei Li, Bayinqiaoge, Zhiwu Xu, Shi-Yang Tang, Zhiyuan Liu
Mechanistic insights into CDCP1 clustering on non-small-cell lung cancer
membranes revealed by super-resolution fluorescent imaging
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Xiao Qi, Zihao Li, Jinrui Zhang, Hongru Li, Guangxin Zhang, Meng Li, Baofeng Li, Yilin Fu, Mingjun Cai, Hongda Wang, Ti Tong, Jing Gao
Salmonella infection induces the reorganization of follicular dendritic
cell networks concomitant with the failure to generate germinal centers
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Edith Marcial-Juárez, Marisol Pérez-Toledo, Saba Nayar, Elena Pipi, Areej Alshayea, Ruby Persaud, Sian E. Jossi, Rachel Lamerton, Francesca Barone, Ian R. Henderson, Adam F. Cunningham
Hepatic ZBTB22-mediated detoxification ameliorates acetaminophen-induced
liver injury by inhibiting pregnane X receptor signaling
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Yingjian Chen, Tianqi Cui, Shaorong Xiao, Tianyao Li, Yadi Zhong, Kaijia Tang, Jingyi Guo, Shangyi Huang, Jiabing Chen, Jiayu Li, Qi Wang, Jiawen Huang, Huafeng Pan, Yong Gao
Single-cell RNA sequencing reveals maturation trajectory in human
pluripotent stem cell-derived cardiomyocytes in engineered tissues
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Shangli Cheng, David Brenière-Letuffe, Virpi Ahola, Andy O.T. Wong, Hoi Yee Keung, Bimal Gurung, Zongli Zheng, Kevin D. Costa, Deborah K. Lieu, Wendy Keung, Ronald A. Li
Superatomic states under high pressure
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Rui Wang, Xinrui Yang, Wanrong Huang, Zhonghua Liu, Yu Zhu, Hanyu Liu, Zhigang Wang
Systematic analysis of the aberrances and functional implications of
cuproptosis in cancer
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Jiangbing Li, Boyan Li, Rongrong Zhao, Gang Li
The vitellogenin receptor gene contributes to mating and host-searching
behaviors in parasitoid wasps
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Yifeng Sheng, Jiani Chen, Hanyu Jiang, Yueqi Lu, Zhi Dong, Lan Pang, Junwei Zhang, Ying Wang, Xuexin Chen, Jianhua Huang
Toll-like receptor 4 signaling in osteoblasts is required for load-induced
bone formation in mice
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Ibtesam Rajpar, Gaurav Kumar, Paolo Fortina, Ryan E. Tomlinson
Restricting genomic actions of innate immune mediators on fetal
hematopoietic progenitor cells
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Vu L. Tran, Peng Liu, Koichi R. Katsumura, Erin Kim, Bjorn M. Schoff, Kirby D. Johnson, Emery H. Bresnick
Liver development during Xenopus tropicalis metamorphosis is controlled by
T3-activation of WNT signaling
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Yuta Tanizaki, Shouhong Wang, Hongen Zhang, Yuki Shibata, Yun-Bo Shi
SARS-CoV-2 IgG seroprevalence surveys in blood donors before the
vaccination campaign, France 2020-2021
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Pierre Gallian, Nathanaël Hozé, Nadège Brisbarre, Paola Mariela Saba Villarroel, Elif Nurtop, Christine Isnard, Boris Pastorino, Pascale Richard, Pascal Morel, Simon Cauchemez, Xavier de Lamballerie
A phenomenological cartography of misophonia and other forms of sound
intolerance
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Nora Andermane, Mathilde Bauer, Ediz Sohoglu, Julia Simner, Jamie Ward
Strain induced metal-semiconductor transition in two-dimensional
topological half metals
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Jing-Yang You
Administration of prosaposin-derived neurotrophic factor to neural tube
defects facilitates regeneration and restores neurological functions
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Sakirul Khan, Akihide Takeuchi, Hiroaki Nabeka, Farzana Khan, Tetsuya Shimokawa, Sota Takanezawa, Takashi Saitou, Takeshi Imamura, Tetsuya Tachibana, Akira Nishizono, Fumihiko Hamada, Seiji Matsuda
Monovalent and trivalent VSV-based COVID-19 vaccines elicit neutralizing
antibodies and CD8+ T cells against SARS-CoV-2 variants
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Kate A. Parham, Gyoung Nyoun Kim, Connor G. Richer, Marina Ninkov, Kunyu Wu, Nasrin Saeedian, Yue Li, Rasheduzzaman Rashu, Stephen D. Barr, Eric J. Arts, S.M. Mansour Haeryfar, C. Yong Kang, Ryan M. Troyer
Phenotypic dimorphism between honeybee queen and worker is regulated by
complicated epigenetic modifications
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Meng Jie Jin, Zi Long Wang, Zhi Hao Wu, Xu Jiang He, Yong Zhang, Qiang Huang, Li Zhen Zhang, Xiao Bo Wu, Wei Yu Yan, Zhi Jiang Zeng
Oral metformin transiently lowers post-prandial glucose response by
reducing the apical expression of sodium-glucose co-transporter 1 in
enterocytes
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Lorea Zubiaga, Olivier Briand, Florent Auger, Veronique Touche, Thomas Hubert, Julien Thevenet, Camille Marciniak, Audrey Quenon, Caroline Bonner, Simon Peschard, Violeta Raverdy, Mehdi Daoudi, Julie Kerr-Conte, Gianni Pasquetti, Hermann Koepsell, Daniela Zdzieblo, Markus Mühlemann, Bernard Thorens, Nathalie D. Delzenne, Laure B. Bindels
Artificial intelligence-based HDX (AI-HDX) prediction reveals fundamental
characteristics to protein dynamics: Mechanisms on SARS-CoV-2 immune
escape
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Jiali Yu, Ugur Uzuner, Bin Long, Zachary Wang, Joshua S. Yuan, Susie Y. Dai
Cocaine and habit training cause dendritic spine rearrangement in the
prelimbic cortex
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Michelle K. Sequeira, Andrew M. Swanson, Henry W. Kietzman, Shannon L. Gourley
Intrinsic sexual dimorphism in the placenta determines the differential
response to benzene exposure
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Anthony Maxwell, Nicholas Adzibolosu, Anna Hu, Yuan You, Paul M. Stemmer, Douglas M. Ruden, Michael C. Petriello, Marianna Sadagurski, Lucas K. Debarba, Lisa Koshko, Jayanth Ramadoss, Annie Thy Nguyen, Darby Richards, Aihua Liao, Gil Mor, Jiahui Ding
Implantation of engineered human microvasculature to study human
infectious diseases in mouse models
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Sophia Schönherr-Hellec, Eirini Chatzopoulou, Jean-Philippe Barnier, Yoann Atlas, Sébastien Dupichaud, Thomas Guilbert, Yves Dupraz, Julie Meyer, Catherine Chaussain, Caroline Gorin, Xavier Nassif, Stephane Germain, Laurent Muller, Mathieu Coureuil
Cancer researchers’ perceptions of the importance of the sex of cell
lines, animals, and human samples for cancer biology research
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Berna C. Özdemir, Anke Richters, Cristina Espinosa da Silva, Alison May Berner
Cancer vaccines based on whole-tumor lysate or neoepitopes with validated
HLA binding outperform those with predicted HLA-binding affinity
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Hajer Fritah, Michele Graciotti, Cheryl Lai-Lai Chiang, Anne-Laure Huguenin- Bergenat, Rémy Petremand, Ritaparna Ahmed, Philippe Guillaume, Julien Schmidt, Brian J. Stevenson, David Gfeller, Alexandre Harari, Lana E. Kandalaft
Activation of AMP-activated protein kinase (AMPK) through inhibiting
interaction with prohibitins
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Shuhei Kanagaki, Yusuke Tsutsui, Naoki Kobayashi, Takashi Komine, Minoru Ito, Yunike Akasaka, Michiaki Nagasawa, Tomohiro Ide, Naoki Omae, Kazuhisa Nakao, Makoto Rembutsu, Maki Iwago, Aki Yonezawa, Yusei Hosokawa, Tetsuya Hosooka, Wataru Ogawa, Koji Murakami
Matrix stiffness induces epithelial-to-mesenchymal transition via
Piezo1-regulated calcium flux in prostate cancer cells
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Maria Lopez-Cavestany, Su Bin Hahn, Jacob M. Hope, Noah T. Reckhorn, Joshua D. Greenlee, Samantha C. Schwager, Jacob A. VanderBurgh, Cynthia A. Reinhart-King, Michael R. King
Mutating novel interaction sites in NRP1 reduces SARS-CoV-2 spike protein
internalization
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Debjani Pal, Kuntal De, Timothy B. Yates, Jaydeep Kolape, Wellington Muchero
A model of decentralized vision in the sea urchin Diadema
africanum
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Tianshu Li, John Kirwan, Maria Ina Arnone, Dan-Eric Nilsson, Giancarlo La Camera
Nanostructured silicon photocatalysts for solar-driven fuel production
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Sarrah Putwa, Isabel S. Curtis, Mita Dasog
Short-term synaptic plasticity in emerging devices for neuromorphic
computing
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Chao Li, Xumeng Zhang, Pei Chen, Keji Zhou, Jie Yu, Guangjian Wu, Du Xiang, Hao Jiang, Ming Wang, Qi Liu
Modulation of skyrmionic magnetic textures in two-dimensional vdW
materials and their heterostructures
- Abstract: Publication date: 21 April 2023Source: iScience, Volume 26, Issue 4Author(s): Xiaoyan Yao, Di Hu, Shuai Dong
Transient receptor potential canonical type 6 (TRPC6) O-GlcNAcylation at
Threonine-221 plays potent role in channel regulation
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Sumita Mishra, Junfeng Ma, Desirae McKoy, Masayuki Sasaki, Federica Farinelli, Richard C. Page, Mark J. Ranek, Natasha Zachara, David A. Kass
Microglia depletion prevents lactation by inhibition of prolactin
secretion
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Vivien Csikós, Szilvia Oláh, Fanni Dóra, Nikolett Arrasz, Melinda Cservenák, Arpád Dobolyi
Neuronal loss of NCLX-dependent mitochondrial calcium efflux mediates
age-associated cognitive decline
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Pooja Jadiya, Henry M. Cohen, Devin W. Kolmetzky, Ashlesha A. Kadam, Dhanendra Tomar, John W. Elrod
Chemogenetic activation of astrocytes promotes remyelination and restores
cognitive deficits in visceral hypersensitive rats
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Mahadi Hasan, Zhuogui Lei, Mastura Akter, Zafar Iqbal, Faeeqa Usaila, Aruna Surendran Ramkrishnan, Ying Li
Mixed lineage kinase-like protein protects against Clostridium perfringens
infection by enhancing NLRP3 inflammasome-extracellular traps axis
- Abstract: Publication date: 17 March 2023Source: iScience, Volume 26, Issue 3Author(s): Yang Liu, Li-Hua Xing, Fen-Xin Li, Na Wang, Yu-Ze Ma, Jian-Wei Li, Yu-Jing Wu, Jing Liang, Yu-Xin Lei, Xue-Yin Wang, Fan-Hua Meng, Yong-Jun Yang, Guang-Peng Li, Xiao Wang, Shui-Xing Yu