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  Subjects -> SCIENCES: COMPREHENSIVE WORKS (Total: 374 journals)
Showing 1 - 200 of 265 Journals sorted alphabetically
Accountability in Research: Policies and Quality Assurance     Hybrid Journal   (Followers: 19)
Acta Nova     Open Access   (Followers: 2)
Acta Scientifica Malaysia     Open Access   (Followers: 1)
Acta Scientifica Naturalis     Open Access   (Followers: 4)
Adıyaman University Journal of Science     Open Access  
Advanced Science     Open Access   (Followers: 16)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 8)
Advanced Theory and Simulations     Hybrid Journal   (Followers: 4)
Advances in Research     Open Access  
Advances in Science and Technology     Full-text available via subscription   (Followers: 18)
African Journal of Science, Technology, Innovation and Development     Hybrid Journal   (Followers: 8)
Afrique Science : Revue Internationale des Sciences et Technologie     Open Access   (Followers: 1)
AFRREV STECH : An International Journal of Science and Technology     Open Access   (Followers: 3)
Alfarama Journal of Basic & Applied Sciences     Open Access   (Followers: 12)
American Academic & Scholarly Research Journal     Open Access   (Followers: 4)
American Journal of Applied Sciences     Open Access   (Followers: 22)
American Journal of Humanities and Social Sciences     Open Access   (Followers: 14)
Anales del Instituto de la Patagonia     Open Access  
Applied Mathematics and Nonlinear Sciences     Open Access   (Followers: 2)
Arab Journal of Basic and Applied Sciences     Open Access  
Arabian Journal for Science and Engineering     Hybrid Journal   (Followers: 1)
Archives Internationales d'Histoire des Sciences     Partially Free   (Followers: 5)
Archives of Current Research International     Open Access  
ARPHA Conference Abstracts     Open Access   (Followers: 1)
ARPHA Proceedings     Open Access  
Asian Journal of Advanced Research and Reports     Open Access  
Asian Journal of Scientific Research     Open Access   (Followers: 2)
Asian Journal of Technology Innovation     Hybrid Journal   (Followers: 5)
Australian Field Ornithology     Full-text available via subscription   (Followers: 1)
Australian Journal of Social Issues     Hybrid Journal   (Followers: 6)
Bangladesh Journal of Scientific Research     Open Access  
Beni-Suef University Journal of Basic and Applied Sciences     Open Access   (Followers: 1)
Berichte Zur Wissenschaftsgeschichte     Hybrid Journal   (Followers: 11)
Bilge International Journal of Science and Technology Research     Open Access  
Bioethics Research Notes     Full-text available via subscription   (Followers: 15)
BJHS Themes     Open Access   (Followers: 1)
Bulletin de la Société Royale des Sciences de Liège     Open Access  
Bulletin of the National Research Centre     Open Access  
Chain Reaction     Full-text available via subscription  
Ciencia Amazónica (Iquitos)     Open Access  
Ciencia en su PC     Open Access   (Followers: 1)
Ciencia Ergo Sum     Open Access  
Ciência ET Praxis     Open Access  
Communications Faculty of Sciences University of Ankara Series A2-A3 Physical Sciences and Engineering     Open Access  
Comunicata Scientiae     Open Access  
Conference Papers in Science     Open Access  
Configurations     Full-text available via subscription   (Followers: 11)
COSMOS     Hybrid Journal   (Followers: 1)
Crea Ciencia Revista Científica     Open Access  
Current Issues in Criminal Justice     Hybrid Journal   (Followers: 14)
Current Research in Geoscience     Open Access   (Followers: 6)
Data     Open Access   (Followers: 4)
Dhaka University Journal of Science     Open Access  
Discover Sustainability     Open Access   (Followers: 5)
Einstein (São Paulo)     Open Access  
Ekaia : EHUko Zientzia eta Teknologia aldizkaria     Open Access  
Emergent Scientist     Open Access  
Enhancing Learning in the Social Sciences     Open Access   (Followers: 7)
Enseñanza de las Ciencias : Revista de Investigación y Experiencias Didácticas     Open Access  
Entramado     Open Access  
Entre Ciencia e Ingeniería     Open Access  
Epiphany     Open Access   (Followers: 1)
Ethiopian Journal of Education and Sciences     Open Access   (Followers: 5)
European Online Journal of Natural and Social Sciences     Open Access   (Followers: 4)
European Scientific Journal     Open Access   (Followers: 11)
Evidência - Ciência e Biotecnologia - Interdisciplinar     Open Access  
Exchanges : the Warwick Research Journal     Open Access   (Followers: 1)
Experimental Results     Open Access   (Followers: 2)
Fides et Ratio : Revista de Difusión Cultural y Científica     Open Access  
Fontanus     Open Access   (Followers: 1)
Forensic Science Policy & Management: An International Journal     Hybrid Journal   (Followers: 266)
Frontiers in Climate     Open Access   (Followers: 5)
Frontiers in Science     Open Access   (Followers: 1)
Fundamental Research     Open Access  
Futures & Foresight Science     Hybrid Journal   (Followers: 1)
Gaudium Sciendi     Open Access  
Ghana Studies     Full-text available via subscription   (Followers: 15)
Global Journal of Pure and Applied Sciences     Full-text available via subscription  
Globe, The     Full-text available via subscription   (Followers: 4)
HardwareX     Open Access  
Heidelberger Jahrbücher Online     Open Access  
Heliyon     Open Access   (Followers: 1)
History of Science and Technology     Open Access   (Followers: 5)
Hoosier Science Teacher     Open Access  
Indian Journal of History of Science     Hybrid Journal   (Followers: 3)
Instruments     Open Access  
Interciencia     Open Access  
International Annals of Science     Open Access  
International Journal of Advanced Multidisciplinary Research and Review     Open Access  
International Journal of Applied Science     Open Access  
International Journal of Engineering, Science and Technology     Open Access  
International Journal of Network Science     Hybrid Journal   (Followers: 3)
International Journal of Social Sciences and Management     Open Access   (Followers: 3)
International Journal of Technology Policy and Law     Hybrid Journal   (Followers: 10)
International Science and Technology Journal of Namibia     Open Access   (Followers: 2)
International Scientific and Vocational Studies Journal     Open Access  
Investiga : TEC     Open Access  
Investigación Joven     Open Access  
Investigacion y Ciencia     Open Access   (Followers: 1)
Iranian Journal of Science and Technology, Transactions A : Science     Hybrid Journal  
iScience     Open Access   (Followers: 2)
Issues in Science & Technology     Free   (Followers: 9)
Ithaca : Viaggio nella Scienza     Open Access  
J : Multidisciplinary Scientific Journal     Open Access  
Jaunujų mokslininkų darbai     Open Access   (Followers: 3)
Journal de la Recherche Scientifique de l'Universite de Lome     Full-text available via subscription  
Journal of Chromatography & Separation Techniques     Open Access   (Followers: 9)
Journal of Advanced Research     Open Access   (Followers: 2)
Journal of Analytical Science & Technology     Open Access   (Followers: 5)
Journal of Applied Science and Technology     Full-text available via subscription   (Followers: 1)
Journal of Applied Sciences and Environmental Management     Open Access   (Followers: 1)
Journal of Big History     Open Access   (Followers: 4)
Journal of Composites Science     Open Access   (Followers: 4)
Journal of Diversity Management     Open Access   (Followers: 4)
Journal of Indian Council of Philosophical Research     Hybrid Journal  
Journal of Institute of Science and Technology     Open Access  
Journal of King Saud University - Science     Open Access  
Journal of Mathematical and Fundamental Sciences     Open Access  
Journal of Negative and No Positive Results     Open Access  
Journal of Responsible Technology     Open Access  
Journal of Science and Technology     Open Access   (Followers: 2)
Journal of Science and Technology     Open Access   (Followers: 1)
Journal of Science and Technology (Ghana)     Open Access   (Followers: 3)
Journal of Science and Technology Policy Management     Hybrid Journal   (Followers: 1)
Journal of Science Foundation     Open Access   (Followers: 1)
Journal of Scientific Research and Reports     Open Access   (Followers: 1)
Journal of Shanghai Jiaotong University (Science)     Hybrid Journal  
Journal of Social Science Research     Open Access   (Followers: 2)
Journal of Taibah University for Science     Open Access  
Journal of the Ghana Science Association     Full-text available via subscription   (Followers: 3)
Journal of the History of Ideas     Full-text available via subscription   (Followers: 176)
Journal of the Indian Institute of Science     Hybrid Journal   (Followers: 4)
Journal of the Royal Society of New Zealand     Hybrid Journal   (Followers: 49)
Journal of the South Carolina Academy of Science     Open Access  
Journal of Unsolved Questions     Open Access  
Jurnal Sains Dasar     Open Access  
Jurnal Teknosains     Open Access  
Karaelmas Science and Engineering Journal     Open Access  
Karbala International Journal of Modern Science     Open Access  
Kennedy Institute of Ethics Journal     Full-text available via subscription   (Followers: 10)
Logo STI Science, Technology and Innovation     Open Access   (Followers: 14)
Malawi Journal of Science and Technology     Open Access   (Followers: 6)
Maskana     Open Access  
MethodsX     Open Access  
Mètode Science Studies Journal : Annual Review     Open Access  
Modern Applied Science     Open Access   (Followers: 1)
Momona Ethiopian Journal of Science     Open Access   (Followers: 5)
National Academy Science Letters     Hybrid Journal   (Followers: 3)
National Science Review     Hybrid Journal   (Followers: 1)
Natural Sciences     Open Access  
Natural Sciences Education     Hybrid Journal   (Followers: 1)
Naturen     Full-text available via subscription  
Nepal Journal of Science and Technology     Open Access  
Network Science     Hybrid Journal   (Followers: 4)
Nordic Journal of Science and Technology     Open Access   (Followers: 2)
Nordic Studies in Science Education     Open Access   (Followers: 4)
Nova     Open Access  
Open Conference Proceedings Journal     Open Access  
Open Journal of Applied Sciences     Open Access  
Orbis Cógnita : Revista Científica     Open Access   (Followers: 2)
Patterns     Open Access   (Followers: 9)
People and Nature     Open Access   (Followers: 4)
Población y Desarrollo - Argonautas y caminantes     Open Access  
Politique et Sociétés     Full-text available via subscription   (Followers: 1)
Portal de la Ciencia     Open Access  
Proceedings of the Indian National Science Academy     Full-text available via subscription   (Followers: 5)
Proceedings of the Linnean Society of New South Wales     Full-text available via subscription   (Followers: 2)
Proceedings of the Royal Society of Queensland, The     Full-text available via subscription  
QScience Connect     Open Access  
Quantum Science and Technology     Hybrid Journal   (Followers: 15)
Rafidain Journal of Science     Open Access  
Rehabilitation Research, Policy, and Education     Hybrid Journal   (Followers: 2)
Reportes Científicos de la FaCEN     Open Access  
Reports in Advances of Physical Sciences     Open Access  
Research Ideas and Outcomes     Open Access  
Research Integrity and Peer Review     Open Access   (Followers: 1)
Research Policy : X     Open Access   (Followers: 3)
Respuestas     Open Access  
Revista Bases de la Ciencia     Open Access  
Revista Cientifica Guillermo de Ockham     Open Access  
Revista Conhecimento Online     Open Access  
Revista Crítica de Ciências Sociais     Open Access  
Revista de Ciencia y Tecnología     Open Access  
Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales     Open Access  
Revista de la Universidad del Zulia     Open Access  
Revista Politécnica     Open Access  
Revista Tecnológica     Open Access  
Revista UniVap     Open Access  
SAINSTIS     Open Access  
Sainteknol : Jurnal Sains dan Teknologi     Open Access  
Sci     Open Access  
Science     Full-text available via subscription   (Followers: 5206)
Science & Diplomacy     Free   (Followers: 3)
Science Advances     Free   (Followers: 45)
Science and Technology     Open Access   (Followers: 2)
Science Heritage Journal     Open Access  
Science World Journal     Open Access  
Science, Technology and Arts Research Journal     Open Access   (Followers: 1)
ScienceRise     Open Access  
Sciences du jeu     Open Access  

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Dalat University Journal of Science
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ISSN (Print) 0866-787X
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  • Fatal Case of Possible Thyroid Crisis Induced by SARS-CoV-2 Infection

    • Authors: Febriyani Hamzah, Andi Makbul Aman, Harun Iskandar
      Abstract: Thyroid crisis is an emergency due to impaired thyroid function caused by various conditions, particularly infections such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that result in the dysfunction of various vital organs. We report a case of a 31-year-old Indonesian female with a 2-year history of hyperthyroidism with elevated thyroid-stimulating hormone (TSH) receptor antibodies. (TRAb) who developed thyroid crisis possibly in association with SARS-CoV-2 pneumonia, sepsis, and disseminated intravascular coagulation (DIC). Prior to admission, she was treated for her hyperthyroidism with propylthiouracil and had been in stable remission for a year. She was admitted to the Emergency Room with complaints of watery stools, icteric sclerae, jaundice, coughing, and shortness of breath. The physical examination showed a World Health Organization (WHO) performance score of 4, delirium, blood pressure within normal limits, tachycardia, tachypnea, axillary temperature of 36.7°C, icteric sclerae, jaundice, and exophthalmos. There was a 3 cm palpable nodule on the right side of the neck. Auscultation of the lungs revealed bilateral pulmonary rales. Abdominal examination noted a palpable liver and enlarged spleen. Laboratory tests showed thrombocytopenia, electrolyte imbalance, hypoalbuminemia and elevated transaminases. The thyroid function tests showed a suppressed TSH level with an elevated free thyroxine (FT4) level. The SARS-CoV-2 polymerase chain reaction (PCR) swab test was positive. Initial patient management was with supportive therapy that included favipiravir and anti-hyperthyroidism medication; however, despite these interventions, her condition continued to deteriorate and she died after a few hours. This case demonstrates no difference in therapy between patients with thyroid crises and COVID-19 or other infections. Proper and timely treatment is important for reducing mortality rates.
      PubDate: 2022-11-09
      Issue No: Vol. 37, No. 2 (2022)
       
  • Atypical Eruptive Xanthoma

    • Authors: Yotsapon Thewjitcharoen, Natthakan Saiwaew, Soontaree Nakasatien, Thep Himathongkam
      Abstract: Since May 2022, monkeypox outbreaks have been reported in several countries outside Africa. The typical skin lesions of monkeypox begin as papules that appear in possible areas of inoculation, such as the skin or mucous membranes, followed by generalized pustules. Systemic symptoms appear simultaneously or a few days earlier than the lesions.
      PubDate: 2022-10-28
      Issue No: Vol. 37, No. 2 (2022)
       
  • A Comparison of Statin Treatment Algorithms based on the ACC/AHA and
           Philippine Guidelines for Primary Prevention of Dyslipidemia in
           Statin-Naive Filipino Patients

    • Authors: Bayani Pocholo Maglinte, Alex Junia, Jeremyjones Robles
      Abstract: Objectives. This cross-sectional study evaluates the degree of agreement between the 2018 American College of Cardiology/American Heart Association (ACC/AHA2018) and 2020 Philippine guideline (PG2020) treatment algorithms for the primary prevention of dyslipidemia among Filipinos. Methodology. This review included 159 charts of tatin-naive Filipinos who are 45-79 years old. Using risk profile and lipid measurements, statin treatment recommendation was determined through the PG2020 algorithm and ACC/AHA-ASCVD Risk Estimator Plus web application. The degree of agreement was measured by Cohen’s kappa statistic with the two algorithms as independent raters. Results. A total of 159 patients were included in the final analysis. There was a slight agreement with a kappa coefficient of 0.209 or 4.4% (95% CI 0.078-0.340, p=0.003). Statin treatment was recommended in 69 out of 159 patients (43.4%) by the PG2020 overlapping with ACC/AHA2018 in 56 cases (81.2%). On the other hand, 109 cases (68.6%) were recommended for statin treatment by ACC/AHA2018 overlapping with PG2020 in only 51.4%. Conclusions. The low degree of agreement between the two treatment algorithms highlights the key demographic and ethnic variations in dyslipidemia management necessitating outcome-based studies to translate these differences. Overestimation of ASCVD risk calculation in the ACC/AHA2018 and consideration of important, unique risk factors among Filipinos favors the applicability of the Philippine guideline.
      PubDate: 2022-09-15
      Issue No: Vol. 37, No. 2 (2022)
       
  • Glycaemic Changes among Children and Adolescents with Type 1 Diabetes
           Mellitus Before and During Ramadan Fasting using Continuous Glucose
           Monitoring

    • Authors: Sze Teik Teoh, Suhaimi Hussain, Janet Yeow Hua Hong
      Abstract: Objectives . This study described and compared glycaemic changes with the use of the following Continuous Glucose Monitoring (CGM) metrics: time in range, time in hyperglycaemia and time in hypoglycaemia from retrospective CGM data among children and adolescents with Type 1 Diabetes Mellitus (T1DM), before and during Ramadan to better understand the impact of fasting during this season. Methodology. This study was conducted in 2 tertiary centres: Hospital Putrajaya (HPJ) and Hospital Universiti Sains Malaysia (HUSM) from February to May 2020. Muslim T1DM patients between ages 8 to18 who intended to fast during Ramadan were given Ramadan-focused education. CGM iPro2® (Medtronic) was used before and during Ramadan, complemented by finger-prick glucose monitoring or self-monitoring of blood glucose (SMBG). Results. Of the 32 patients, only 24 (12 female) were analysed. Mean age was 13.6 ± 3.1 years old, mean HbAlc was 9.6 ± 1.9% and mean duration of illness was 5.4 ± 3.4 years. Majority (91.7%) were on multiple dose injections (MDI) while only 8.3% were on continuous subcutaneous insulin infusion (CSII). All fasted in Ramadan without acute complications. Retrospective CGM analysis revealed similar results in time in range (TIR), time in hyperglycaemia and time in hypoglycaemia before and during Ramadan, indicating no increased hypoglycaemic or hyperglycaemic events related to fasting. Glycaemic variability before Ramadan as measured by the LBGI, HBGI and MAG, were similar to values during Ramadan. Conclusion. Ramadan fasting among T1DM children and adolescents, by itself, is not associated with short-term glycaemic deterioration. T1DM youths can fast safely in Ramadan with the provision of focused education and regular SMBG.
      PubDate: 2022-09-09
      Issue No: Vol. 37, No. 2 (2022)
       
  • An Atypical Presentation of Primary Hyperparathyroidism with Multiple
           Spontaneous Tendon Ruptures

    • Authors: Jielin Yew, Shui Boon Soh
      Abstract: Primary hyperparathyroidism (PHPT) is a common endocrine condition, increasingly presenting asymptomatically and detected on routine laboratory examination in developed countries. Multiple spontaneous tendon ruptures as the initial presentation of PHPT is extremely rare. We present the case of a 28-year-old male diagnosed with severe hypercalcemia secondary to PHPT after presenting with complications of multiple spontaneous tendon ruptures,and discuss the management issues in PHPT for this patient.
      PubDate: 2022-09-08
      Issue No: Vol. 37, No. 2 (2022)
       
  • Use of Combination of Oral Levothyroxine and Liothyronine in Severe
           Hypothyroidism with Massive Pericardial Effusion

    • Authors: Poh Shean Wong, Sue Wen Lim, Chin Voon Tong, Masni Mohamad, Zanariah Hussein
      Abstract: Thyroid hormone plays an important role in cardiovascular function. Pericardial effusions are commonly seen in cases of severe hypothyroidism. However, large to massive pericardial effusions with cardiac tamponade are exceptionally rare. Herein, we present two cases of severe hypothyroidism with massive pericardial effusion. Our first case demonstrates that a patient with large pericardial effusion can be managed conservatively with aggressive thyroid hormone replacement therapy. In our second case, pericardiocentesis was performed in addition to thyroid hormone replacement therapy as the underlying aetiology of effusion could not be reasonably limited to hypothyroidism. These two cases served to highlight and demonstrate rapid normalisation of thyroid function test by using aggressive oral thyroid hormone replacement therapy using liothyronine, in combination with levothyroxine, which led to resolution of pericardial effusion and prevent its re-accumulation.
      PubDate: 2022-09-05
      Issue No: Vol. 37, No. 2 (2022)
       
  • Comparison of Maternal and Neonatal Outcomes among High-Risk Filipino
           Women with Gestational Diabetes Diagnosed Before and After 24 weeks of
           Gestation

    • Authors: Kriselle Rae Dy, Christy Yao
      Abstract: Objectives. This study determined the prevalence, clinical characteristics and pregnancy outcomes of high-risk women diagnosed with gestational diabetes mellitus (GDM) before and after 24 weeks of gestation. Methodology. This retrospective study included all singleton deliveries with GDM at the Pasig City General Hospital from January 2018 to December 2019. Subjects were grouped into those who were diagnosed with GDM before 24 weeks of gestation (<24 weeks, n=61) and thereafter (≥24 weeks, n=219). Outcomes examined were preeclampsia, cesarean delivery, preterm birth, macrosomia, large-for-gestational age, small-for-gestational age, neonatal hypoglycemia, neonatal ICU admission, congenital malformations and perinatal mortality. Results. The group diagnosed with GDM before 24 weeks was significantly older (33.0 ± 5.7 years versus 29.4 ± 5.9 years, p<0.001), had higher 2-hour 75 g oral glucose tolerance test (OGTT) results (158.2 ± 20.0 mg/dL versus 150.0 ± 23.7 mg/dL, p=0.014), and had more pregnancies with preeclampsia (23.0% versus 9.6%, p=0.005). Conclusion. High-risk women diagnosed with GDM before 24 weeks of gestation had a higher incidence of preeclampsia compared with high-risk women diagnosed with GDM after 24 weeks of gestation.
      PubDate: 2022-08-27
      Issue No: Vol. 37, No. 2 (2022)
       
  • Risk Factors for Inpatient Hypoglycemia in a Tertiary Care Hospital in
           Indonesia

    • Authors: Chici Pratiwi, Martin Rumende, Ida Ayu Made Kshanti , Pradana Soewondo
      Abstract: Introduction. Hypoglycemia is an important and harmful complication that often occurs in inpatient and outpatient settings. This study aims to assess the incidence of inpatient hypoglycemia and its related factors. We also assessed mortality and length of hospital stay. Methodology. We performed a retrospective cohort study among patients with type 2 diabetes mellitus admitted to a tertiary hospital in Indonesia. Using multivariate regression, we analyzed age, sex, body mass index, comorbidities, history of hypoglycemia, hyperglycemia treatment administered, nutritional intake, and medical instruction as the related risk factors for inpatient hypoglycemia. Results. From 475 subjects, 80 (16.8%) had inpatient hypoglycemia, of which, 7.4% experienced severe hypoglycemia. We found that patients with a history of hypoglycemia (RR: 4.6; 95% CI: 2.8-7.6), insulin and/or sulfonylurea treatment (RR 6.4; 95% CI: 1.6-26.5), and inadequate nutritional intake (RR 2.6; 95% CI: 1.5-4.3) were more likely to have hypoglycemic events compared to those who did not. The length of hospital stay for patients in the hypoglycemic group is significantly longer than those in the non-hypoglycemic group (13 vs 7 days, p<0.001), but their mortality rates did not differ (16% vs 10.9%, p=0.18). Conclusion. Inpatient hypoglycemia may be affected by a history of hypoglycemia and inadequate nutritional intake. Patients who had inpatient hypoglycemia tend to have a longer median length of hospital stay.
      PubDate: 2022-08-25
      Issue No: Vol. 37, No. 2 (2022)
       
  • Prevalence of Diabetes among Community-living Older Persons in the
           Philippines

    • Authors: Maria Stella Giron, Shelley Ann de la Vega
      Abstract: Objective. To estimate the prevalence of diabetes among Filipino older persons living in the community. Methodology. A cross-sectional analysis was done on a random sample of persons ages 60 years and older from the Focused Interventions for Frail Older Adults Research and Development Program (2018-2019). A diagnosis of diabetes was established by self-reported physician’s diagnosis or if the person was on any antihyperglycemic drugs. Results. The prevalence of self-reported diabetes was 20.5%, with no difference in age, sex, education, or body mass index between older persons with and without diabetes. The presence of 2 or more comorbidities was significantly more common among older persons with diabetes (p<0.001). Visual impairment (p<0.01), hypertension (p<0.001) and hyperlipidemia (p <0.001) were more frequent among those with diabetes. Conclusion. Diabetes is prevalent among community-living older Filipinos. Therefore, effective public health measures for diabetes prevention and management are needed for the ever-growing older population, who are at the highest risk for morbidity and mortality.
      PubDate: 2022-08-23
      Issue No: Vol. 37, No. 2 (2022)
       
  • Efficacy and Safety of Semaglutide for Weight Loss in Obesity without
           Diabetes

    • Authors: Hanna Clementine Tan, Oliver Allan Dampil, Maricar Mae Marquez
      Abstract: Background. The weight loss benefit of semaglutide in patients with diabetes is well-documented, but its clinical utility in treating obesity among patients without diabetes is less described. We therefore assessed the efficacy and safety of subcutaneous semaglutide as treatment for obesity in patients without diabetes. Methodology. A comprehensive search of PubMed/MEDLINE, Cochrane and Google scholar was performed to identify trials on the efficacy and safety of subcutaneous semaglutide on patients with obesity without diabetes. Primary outcome was expressed as percent mean weight difference. Secondary outcomes including risk for gastrointestinal adverse events, discontinuation of treatment and serious adverse events were expressed as risk ratios. These were calculated using the random effects model. Results. The study included 4 randomized controlled trials having a total of 3,613 individuals with obesity without diabetes. The mean difference for weight reduction was -11.85%, favoring semaglutide [95% confidence interval (CI) (-12.81,-10.90), p<0.00001]. Secondary outcomes showed that the risk of developing gastrointestinal adverse events was 1.59 times more likely with semaglutide (RR 1.59, 95%CI [1.34, 1.88], p<0.00001). Risk for discontinuation due to adverse events was twice as likely in the semaglutide group (RR 2.19, 95%CI [1.36,3.55], p=0.001) and the risk for serious adverse events was 1.6 times more likely for semaglutide (RR1.60, 95% CI [1.24, 2.07], p=0.0003). Serious events were mostly of gastrointestinal and hepatobiliary disorders such as acute pancreatitis and cholelithiasis. Conclusion. Among individuals with obesity without type 2 diabetes, subcutaneous semaglutide is effective for weight loss with an 11.85% reduction from baseline compared to placebo. This supports the use of semaglutide for weight management in obesity. However, risk of gastrointestinal adverse events, discontinuation of treatment and serious adverse events were higher in the semaglutide group versus placebo.
      PubDate: 2022-08-23
      Issue No: Vol. 37, No. 2 (2022)
       
  • Severe Pericardial Effusion due to Autoimmune Hypothyroidism with
           Levothyroxine Withdrawal and Systemic Lupus Erythematosus

    • Authors: Sylvernon Israel, Katherine Ann Tan, Ma. Felisse Carmen Gomez, Florence Rochelle Gan, Jean Uy-Ho
      Abstract: The presence of autoantibodies is a common link between autoimmune hypothyroidism (AH) and Systemic Lupus Erythematosus (SLE). The coexistence of AH (Hashimoto’s Thyroiditis) and SLE is common; however, massive pericardial effusion (PEEF) with signs of tamponade is extremely rare and only a few cases have been reported in literature. We present a case of a 54-year-old female who came in with progressive dyspnea who was found out to have massive PEEF from overt AH and concurrent SLE, which was successfully managed medically. This gave us valuable insight that massive pericardial effusion occurring in overt hypothyroidism may be secondarily caused by other co-existing disease entities such as SLE. The importance of the correct diagnosis cannot be overemphasized, as this largely contributed to the successful management of this case.
      PubDate: 2022-08-18
      Issue No: Vol. 37, No. 2 (2022)
       
  • Detection of Hemostasis Abnormalities in Type 2 Diabetes Mellitus using
           Thromboelastography

    • Authors: Putu Moda Arsana, Novi Khila Firani, Siti Fatonah, Affa Kiysa Waafi, Adinda Dian Novitasari
      Abstract: Introduction. Type 2 DM (T2DM) is associated with inflammation and vascular dysfunction which impact hemostasis. Thromboelastography (TEG) as a hemostasis assessment method, is not routinely applied in T2DM. Methodology. A cross-sectional study was conducted among T2DM patients attending the Endocrinology Clinic of Saiful Anwar Hospital, Indonesia. Glycemic profiles were determined using fasting plasma glucose (FPG), 2-hour postprandial plasma glucose (2hPPG), and glycosylated hemoglobin (HbA1c). Therapy for T2DM was classified into insulin and non-insulin regimens. The primary and secondary hemostasis profile were examined using TEG and was classified as hypo- hyper- and normo- Result. A total of 57 T2DM patients were included. Kruskal-Wallis test did not reveal a significant association between glycemic profiles and groups of hemostasis. However, the median HbA1c was higher in the hypercoagulable group of primary hemostasis and fibrinolysis. The median FPG and 2hPPG were higher in the normo-coagulable group of secondary hemostasis. Logistic regression did not indicate a significant association between type of therapy for diabetes and hemostasis profile. Conclusion. This study did not find significant associations between glycemic levels and type of DM therapy with hemostasis profiles using the TEG method in patients with T2DM.
      PubDate: 2022-08-13
      Issue No: Vol. 37, No. 2 (2022)
       
  • Adrenocortical Carcinoma with Cushing’s Syndrome and Extensive Tumor
           Thrombosis of the Inferior Vena Cava in a 30-year-old Filipino Female

    • Authors: Kristine Abas, Maria Honolina Gomez, Jennifer Mapanao-Gonong, Rosella Arellano
      Abstract: Adrenocortical carcinoma (ACC) is a rare and aggressive neoplasm with poor prognosis. We report a case of a 30-year-old female who presented with profound classic features of an adrenocorticotrophic hormone (ACTH)-independent Cushing’s syndrome (CS) and a large adrenal mass with massive venous tumor thrombosis of the entire inferior vena cava (IVC), left renal and adrenal veins confirmed by imaging. Adrenal biopsy histopathology and immunohistochemistry confirmed ACC. Systemic palliative chemotherapy was administered. This rare case presents a unique and atypical presentation of an extensive tumor thrombosis of IVC. With the advanced stage at diagnosis, aggressive nature and poor prognosis of the disease, there is still a need to determine viable therapeutic options for metastatic ACC associated with venous invasion.
      PubDate: 2022-08-07
      Issue No: Vol. 37, No. 2 (2022)
       
  • Neonatal Outcomes of Pregnancies Complicated by Maternal Hyperthyroidism

    • Authors: Adlina Awanis Mamat , Noraida Ramli, Najib Majdi Yaacob, Suhaimi Hussain
      Abstract: Objective. This study aimed to determine the proportion, clinical characteristics, hormonal status, median time for normalization of serum thyroxine (FT4) and thyroid-stimulating hormone (TSH) and factors affecting time to thyroid function test (TFT) normalization of neonates born to mothers with maternal hyperthyroidism admitted in our institution. Methodology. This was a retrospective cohort study that included 170 newborns admitted to the Neonatal Intensive Care Unit (NICU) of Hospital Universiti Sains Malaysia (HUSM) with a history of maternal hyperthyroidism from January 2013 until December 2018. We analyzed their baseline demographic and clinical characteristics, maternal thyroid status and antibody levels. Finally, we analyzed newborn thyroid function and thyroid antibodies. Results. The proportion of neonates born to mothers with maternal hyperthyroidism was 0.8% (170 of 20198 neonates within the study period). Seven (4.1%) developed overt hyperthyroidism, while four (2.4%) had thyroid storm. The median time for thyroid function test normalization was 30 days (95% CI: 27.1 to 32.8). The median time for TFT normalization was longer among neonates of mothers with positive thyroid antibodies [46.6 days ( 39.4)] and of mothers who received anti-thyroid treatment [31.7 days (95% CI, 23.5 to 39.9)]. Conclusion. Neonates born to mothers with hyperthyroidism is uncommon. These babies were observed to have a longer time for normalization of thyroid function tests if their mothers had thyroid antibodies or received anti-thyroid treatment.
      PubDate: 2022-08-06
      Issue No: Vol. 37, No. 2 (2022)
       
  • Prevalence of Bacterial Urinary Tract Infection Among Patients with Type 2
           Diabetes Mellitus on Sodium-Glucose Cotransporter-2 Inhibitors

    • Authors: Pankaj Ferwani, Aasim Maldar, Nishitkumar Shah, Phulrenu Chauhan, Manoj Chadha
      Abstract: Background. Genitourinary tract infections, mycotic as well as bacterial, as defined by clinical symptoms, are one of the common adverse effects associated with the use of sodium-glucose cotransporter-2 inhibitors (SGLT2i) in type 2 diabetes mellitus (T2DM) patients in clinical trials. However, Indian data in terms of the prevalence of culture-proven bacterial type of urinary tract infection (UTI), and the causative organism is limited. Objective. This study aimed to determine the prevalence and causative agents of bacterial UTI among patients with T2DM on SGLT2i. Methodology. This was a prospective longitudinal study involving all patients with T2DM who were prescribed with SGLT2i, uncontrolled on other oral anti-diabetic medications, from June 2019 to February 2020. Prevalence of bacterial UTI was evaluated at baseline and 12 weeks after initiation of SGLT2i. Results. A total of 80 patients were started on SGLT2i. One female patient on canagliflozin had significant asymptomatic bacteriuria and the causative agent was Acinetobacter baumannii. One male patient on dapagliflozin had symptomatic urinary tract infection with negative urine culture study. Four patients developed genital mycotic infection. Conclusion. In this real-world study, SGLT2i as a class, was well tolerated with favorable safety profile, and risk of developing significant bacteriuria and/or symptomatic UTI was minimal.
      PubDate: 2022-07-25
      Issue No: Vol. 37, No. 2 (2022)
       
  • Collision of Two Tumors

    • Authors: Marisa Khatijah Borhan, Florence Hui Sieng Tan, Nur Shazwaniza Awang Basry
      Abstract: Acollision tumor involving metastasis to a pituitary adenoma is rare. We describe a case of a 68-year-old Bidayuh woman with underlying treatment-responsive lung adenocarcinoma, who presented with mass effect, panhypopituitarism and polyuria. Her initial imaging study reported pituitary macroadenoma, and she was treated with hormone replacement therapy. She then underwent transsphenoidal tumor debulking surgery with subsequent histopathological findings of a collision tumor of an adenocarcinoma with metastasis to a non-functioning pituitary adenoma.
      PubDate: 2022-06-16
      Issue No: Vol. 37, No. 2 (2022)
       
  • Factors Associated with Dietary Behaviour among Patients with Type 2
           Diabetes Mellitus in Rural Indonesia

    • Authors: Anggraini Dwi Kurnia, Nur Lailatul Masruroh, Nur Melizza, Yoyok Bekti Prasetyo, Herdianti Nur Hidayani
      Abstract: Background. Type 2 Diabetes Mellitus (T2DM) is one of the fastest-growing diseases and most serious major health problems worldwide. Few studies have focused on the association of social support with diabetes-related dietary behaviour. Objective. To examine the relationship between social support and dietary behaviour among patients with diabetes in a rural area of Indonesia. Methodology. This was a descriptive cross-sectional study that included 120 physically healthy patients above 18 years old with type 2 diabetes mellitus for at least 6 months. Data analysis was done using a stepwise regression model. Results. The mean age was 61.97 years (SD = 7.85, range = 52-74); 86.7% of the participants were females. Social support (β = 0.272, p = <0.001), diabetes medications (β = 0.169, p = 0.003), duration of diabetes (β = 0.118, p = 0.0047), and presence of diabetes complications (β = 0.197, p = 0.008) were significant predictors of dietary behaviour and accounted for 34.2% of the variance. Conclusion. Social support, diabetes medications, presence of diabetes complications, and duration of diabetes were associated with improved dietary behaviour. Therefore, social support should be considered when designing dietary interventions for patients with type 2 diabetes mellitus.
      PubDate: 2022-06-16
      Issue No: Vol. 37, No. 2 (2022)
       
 
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  Subjects -> SCIENCES: COMPREHENSIVE WORKS (Total: 374 journals)
Showing 1 - 200 of 265 Journals sorted alphabetically
Accountability in Research: Policies and Quality Assurance     Hybrid Journal   (Followers: 19)
Acta Nova     Open Access   (Followers: 2)
Acta Scientifica Malaysia     Open Access   (Followers: 1)
Acta Scientifica Naturalis     Open Access   (Followers: 4)
Adıyaman University Journal of Science     Open Access  
Advanced Science     Open Access   (Followers: 16)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 8)
Advanced Theory and Simulations     Hybrid Journal   (Followers: 4)
Advances in Research     Open Access  
Advances in Science and Technology     Full-text available via subscription   (Followers: 18)
African Journal of Science, Technology, Innovation and Development     Hybrid Journal   (Followers: 8)
Afrique Science : Revue Internationale des Sciences et Technologie     Open Access   (Followers: 1)
AFRREV STECH : An International Journal of Science and Technology     Open Access   (Followers: 3)
Alfarama Journal of Basic & Applied Sciences     Open Access   (Followers: 12)
American Academic & Scholarly Research Journal     Open Access   (Followers: 4)
American Journal of Applied Sciences     Open Access   (Followers: 22)
American Journal of Humanities and Social Sciences     Open Access   (Followers: 14)
Anales del Instituto de la Patagonia     Open Access  
Applied Mathematics and Nonlinear Sciences     Open Access   (Followers: 2)
Arab Journal of Basic and Applied Sciences     Open Access  
Arabian Journal for Science and Engineering     Hybrid Journal   (Followers: 1)
Archives Internationales d'Histoire des Sciences     Partially Free   (Followers: 5)
Archives of Current Research International     Open Access  
ARPHA Conference Abstracts     Open Access   (Followers: 1)
ARPHA Proceedings     Open Access  
Asian Journal of Advanced Research and Reports     Open Access  
Asian Journal of Scientific Research     Open Access   (Followers: 2)
Asian Journal of Technology Innovation     Hybrid Journal   (Followers: 5)
Australian Field Ornithology     Full-text available via subscription   (Followers: 1)
Australian Journal of Social Issues     Hybrid Journal   (Followers: 6)
Bangladesh Journal of Scientific Research     Open Access  
Beni-Suef University Journal of Basic and Applied Sciences     Open Access   (Followers: 1)
Berichte Zur Wissenschaftsgeschichte     Hybrid Journal   (Followers: 11)
Bilge International Journal of Science and Technology Research     Open Access  
Bioethics Research Notes     Full-text available via subscription   (Followers: 15)
BJHS Themes     Open Access   (Followers: 1)
Bulletin de la Société Royale des Sciences de Liège     Open Access  
Bulletin of the National Research Centre     Open Access  
Chain Reaction     Full-text available via subscription  
Ciencia Amazónica (Iquitos)     Open Access  
Ciencia en su PC     Open Access   (Followers: 1)
Ciencia Ergo Sum     Open Access  
Ciência ET Praxis     Open Access  
Communications Faculty of Sciences University of Ankara Series A2-A3 Physical Sciences and Engineering     Open Access  
Comunicata Scientiae     Open Access  
Conference Papers in Science     Open Access  
Configurations     Full-text available via subscription   (Followers: 11)
COSMOS     Hybrid Journal   (Followers: 1)
Crea Ciencia Revista Científica     Open Access  
Current Issues in Criminal Justice     Hybrid Journal   (Followers: 14)
Current Research in Geoscience     Open Access   (Followers: 6)
Data     Open Access   (Followers: 4)
Dhaka University Journal of Science     Open Access  
Discover Sustainability     Open Access   (Followers: 5)
Einstein (São Paulo)     Open Access  
Ekaia : EHUko Zientzia eta Teknologia aldizkaria     Open Access  
Emergent Scientist     Open Access  
Enhancing Learning in the Social Sciences     Open Access   (Followers: 7)
Enseñanza de las Ciencias : Revista de Investigación y Experiencias Didácticas     Open Access  
Entramado     Open Access  
Entre Ciencia e Ingeniería     Open Access  
Epiphany     Open Access   (Followers: 1)
Ethiopian Journal of Education and Sciences     Open Access   (Followers: 5)
European Online Journal of Natural and Social Sciences     Open Access   (Followers: 4)
European Scientific Journal     Open Access   (Followers: 11)
Evidência - Ciência e Biotecnologia - Interdisciplinar     Open Access  
Exchanges : the Warwick Research Journal     Open Access   (Followers: 1)
Experimental Results     Open Access   (Followers: 2)
Fides et Ratio : Revista de Difusión Cultural y Científica     Open Access  
Fontanus     Open Access   (Followers: 1)
Forensic Science Policy & Management: An International Journal     Hybrid Journal   (Followers: 266)
Frontiers in Climate     Open Access   (Followers: 5)
Frontiers in Science     Open Access   (Followers: 1)
Fundamental Research     Open Access  
Futures & Foresight Science     Hybrid Journal   (Followers: 1)
Gaudium Sciendi     Open Access  
Ghana Studies     Full-text available via subscription   (Followers: 15)
Global Journal of Pure and Applied Sciences     Full-text available via subscription  
Globe, The     Full-text available via subscription   (Followers: 4)
HardwareX     Open Access  
Heidelberger Jahrbücher Online     Open Access  
Heliyon     Open Access   (Followers: 1)
History of Science and Technology     Open Access   (Followers: 5)
Hoosier Science Teacher     Open Access  
Indian Journal of History of Science     Hybrid Journal   (Followers: 3)
Instruments     Open Access  
Interciencia     Open Access  
International Annals of Science     Open Access  
International Journal of Advanced Multidisciplinary Research and Review     Open Access  
International Journal of Applied Science     Open Access  
International Journal of Engineering, Science and Technology     Open Access  
International Journal of Network Science     Hybrid Journal   (Followers: 3)
International Journal of Social Sciences and Management     Open Access   (Followers: 3)
International Journal of Technology Policy and Law     Hybrid Journal   (Followers: 10)
International Science and Technology Journal of Namibia     Open Access   (Followers: 2)
International Scientific and Vocational Studies Journal     Open Access  
Investiga : TEC     Open Access  
Investigación Joven     Open Access  
Investigacion y Ciencia     Open Access   (Followers: 1)
Iranian Journal of Science and Technology, Transactions A : Science     Hybrid Journal  
iScience     Open Access   (Followers: 2)
Issues in Science & Technology     Free   (Followers: 9)
Ithaca : Viaggio nella Scienza     Open Access  
J : Multidisciplinary Scientific Journal     Open Access  
Jaunujų mokslininkų darbai     Open Access   (Followers: 3)
Journal de la Recherche Scientifique de l'Universite de Lome     Full-text available via subscription  
Journal of Chromatography & Separation Techniques     Open Access   (Followers: 9)
Journal of Advanced Research     Open Access   (Followers: 2)
Journal of Analytical Science & Technology     Open Access   (Followers: 5)
Journal of Applied Science and Technology     Full-text available via subscription   (Followers: 1)
Journal of Applied Sciences and Environmental Management     Open Access   (Followers: 1)
Journal of Big History     Open Access   (Followers: 4)
Journal of Composites Science     Open Access   (Followers: 4)
Journal of Diversity Management     Open Access   (Followers: 4)
Journal of Indian Council of Philosophical Research     Hybrid Journal  
Journal of Institute of Science and Technology     Open Access  
Journal of King Saud University - Science     Open Access  
Journal of Mathematical and Fundamental Sciences     Open Access  
Journal of Negative and No Positive Results     Open Access  
Journal of Responsible Technology     Open Access  
Journal of Science and Technology     Open Access   (Followers: 2)
Journal of Science and Technology     Open Access   (Followers: 1)
Journal of Science and Technology (Ghana)     Open Access   (Followers: 3)
Journal of Science and Technology Policy Management     Hybrid Journal   (Followers: 1)
Journal of Science Foundation     Open Access   (Followers: 1)
Journal of Scientific Research and Reports     Open Access   (Followers: 1)
Journal of Shanghai Jiaotong University (Science)     Hybrid Journal  
Journal of Social Science Research     Open Access   (Followers: 2)
Journal of Taibah University for Science     Open Access  
Journal of the Ghana Science Association     Full-text available via subscription   (Followers: 3)
Journal of the History of Ideas     Full-text available via subscription   (Followers: 176)
Journal of the Indian Institute of Science     Hybrid Journal   (Followers: 4)
Journal of the Royal Society of New Zealand     Hybrid Journal   (Followers: 49)
Journal of the South Carolina Academy of Science     Open Access  
Journal of Unsolved Questions     Open Access  
Jurnal Sains Dasar     Open Access  
Jurnal Teknosains     Open Access  
Karaelmas Science and Engineering Journal     Open Access  
Karbala International Journal of Modern Science     Open Access  
Kennedy Institute of Ethics Journal     Full-text available via subscription   (Followers: 10)
Logo STI Science, Technology and Innovation     Open Access   (Followers: 14)
Malawi Journal of Science and Technology     Open Access   (Followers: 6)
Maskana     Open Access  
MethodsX     Open Access  
Mètode Science Studies Journal : Annual Review     Open Access  
Modern Applied Science     Open Access   (Followers: 1)
Momona Ethiopian Journal of Science     Open Access   (Followers: 5)
National Academy Science Letters     Hybrid Journal   (Followers: 3)
National Science Review     Hybrid Journal   (Followers: 1)
Natural Sciences     Open Access  
Natural Sciences Education     Hybrid Journal   (Followers: 1)
Naturen     Full-text available via subscription  
Nepal Journal of Science and Technology     Open Access  
Network Science     Hybrid Journal   (Followers: 4)
Nordic Journal of Science and Technology     Open Access   (Followers: 2)
Nordic Studies in Science Education     Open Access   (Followers: 4)
Nova     Open Access  
Open Conference Proceedings Journal     Open Access  
Open Journal of Applied Sciences     Open Access  
Orbis Cógnita : Revista Científica     Open Access   (Followers: 2)
Patterns     Open Access   (Followers: 9)
People and Nature     Open Access   (Followers: 4)
Población y Desarrollo - Argonautas y caminantes     Open Access  
Politique et Sociétés     Full-text available via subscription   (Followers: 1)
Portal de la Ciencia     Open Access  
Proceedings of the Indian National Science Academy     Full-text available via subscription   (Followers: 5)
Proceedings of the Linnean Society of New South Wales     Full-text available via subscription   (Followers: 2)
Proceedings of the Royal Society of Queensland, The     Full-text available via subscription  
QScience Connect     Open Access  
Quantum Science and Technology     Hybrid Journal   (Followers: 15)
Rafidain Journal of Science     Open Access  
Rehabilitation Research, Policy, and Education     Hybrid Journal   (Followers: 2)
Reportes Científicos de la FaCEN     Open Access  
Reports in Advances of Physical Sciences     Open Access  
Research Ideas and Outcomes     Open Access  
Research Integrity and Peer Review     Open Access   (Followers: 1)
Research Policy : X     Open Access   (Followers: 3)
Respuestas     Open Access  
Revista Bases de la Ciencia     Open Access  
Revista Cientifica Guillermo de Ockham     Open Access  
Revista Conhecimento Online     Open Access  
Revista Crítica de Ciências Sociais     Open Access  
Revista de Ciencia y Tecnología     Open Access  
Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales     Open Access  
Revista de la Universidad del Zulia     Open Access  
Revista Politécnica     Open Access  
Revista Tecnológica     Open Access  
Revista UniVap     Open Access  
SAINSTIS     Open Access  
Sainteknol : Jurnal Sains dan Teknologi     Open Access  
Sci     Open Access  
Science     Full-text available via subscription   (Followers: 5206)
Science & Diplomacy     Free   (Followers: 3)
Science Advances     Free   (Followers: 45)
Science and Technology     Open Access   (Followers: 2)
Science Heritage Journal     Open Access  
Science World Journal     Open Access  
Science, Technology and Arts Research Journal     Open Access   (Followers: 1)
ScienceRise     Open Access  
Sciences du jeu     Open Access  

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