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  Subjects -> SCIENCES: COMPREHENSIVE WORKS (Total: 374 journals)
Showing 1 - 200 of 265 Journals sorted alphabetically
AAS Open Research     Open Access  
Accountability in Research: Policies and Quality Assurance     Hybrid Journal   (Followers: 17)
Acta Materialia Transilvanica     Open Access  
Acta Nova     Open Access  
Acta Scientifica Malaysia     Open Access   (Followers: 1)
Acta Scientifica Naturalis     Open Access   (Followers: 2)
Adıyaman University Journal of Science     Open Access  
Advanced Science     Open Access   (Followers: 12)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 4)
Advanced Theory and Simulations     Hybrid Journal   (Followers: 2)
Advances in Research     Open Access  
Advances in Science and Technology     Full-text available via subscription   (Followers: 16)
African Journal of Science, Technology, Innovation and Development     Hybrid Journal   (Followers: 7)
Afrique Science : Revue Internationale des Sciences et Technologie     Open Access   (Followers: 1)
AFRREV STECH : An International Journal of Science and Technology     Open Access   (Followers: 3)
American Academic & Scholarly Research Journal     Open Access   (Followers: 4)
American Journal of Applied Sciences     Open Access   (Followers: 22)
American Journal of Humanities and Social Sciences     Open Access   (Followers: 11)
ANALES de la Universidad Central del Ecuador     Open Access   (Followers: 1)
Anales del Instituto de la Patagonia     Open Access  
Applied Mathematics and Nonlinear Sciences     Open Access  
Apuntes de Ciencia & Sociedad     Open Access  
Arab Journal of Basic and Applied Sciences     Open Access  
Arabian Journal for Science and Engineering     Hybrid Journal   (Followers: 1)
Archives Internationales d'Histoire des Sciences     Partially Free   (Followers: 5)
Archives of Current Research International     Open Access  
ARO. The Scientific Journal of Koya University     Open Access  
ARPHA Conference Abstracts     Open Access   (Followers: 1)
ARPHA Proceedings     Open Access  
ArtefaCToS : Revista de estudios sobre la ciencia y la tecnología     Open Access  
Asian Journal of Advanced Research and Reports     Open Access  
Asian Journal of Scientific Research     Open Access   (Followers: 2)
Asian Journal of Technology Innovation     Hybrid Journal   (Followers: 5)
Australian Field Ornithology     Full-text available via subscription   (Followers: 2)
Australian Journal of Social Issues     Hybrid Journal   (Followers: 6)
Avrasya Terim Dergisi     Open Access  
Bangladesh Journal of Scientific Research     Open Access  
Beni-Suef University Journal of Basic and Applied Sciences     Open Access  
Berichte Zur Wissenschaftsgeschichte     Hybrid Journal   (Followers: 10)
BIBECHANA     Open Access  
Bilge International Journal of Science and Technology Research     Open Access   (Followers: 1)
Bioethics Research Notes     Full-text available via subscription   (Followers: 15)
BJHS Themes     Open Access  
Black Sea Journal of Engineering and Science     Open Access  
Borneo Journal of Resource Science and Technology     Open Access  
Bulletin de la Société Royale des Sciences de Liège     Open Access  
Bulletin of the National Research Centre     Open Access  
Butlletí de la Institució Catalana d'Història Natural     Open Access  
Chain Reaction     Full-text available via subscription  
Ciencia Amazónica (Iquitos)     Open Access  
Ciencia en su PC     Open Access   (Followers: 1)
Ciencia Ergo Sum     Open Access  
Ciência ET Praxis     Open Access  
Ciencia y Tecnología     Open Access  
Ciencias Holguin     Open Access   (Followers: 1)
CienciaUAT     Open Access  
Citizen Science : Theory and Practice     Open Access   (Followers: 1)
Communications Faculty of Sciences University of Ankara Series A2-A3 Physical Sciences and Engineering     Open Access  
Communications in Applied Sciences     Open Access  
Comunicata Scientiae     Open Access  
ConCiencia     Open Access  
Conference Papers in Science     Open Access  
Configurations     Full-text available via subscription   (Followers: 11)
COSMOS     Hybrid Journal   (Followers: 1)
Crea Ciencia Revista Científica     Open Access  
Cuadernos de Investigación UNED     Open Access  
Current Issues in Criminal Justice     Hybrid Journal   (Followers: 15)
Current Research in Geoscience     Open Access   (Followers: 5)
Dalat University Journal of Science     Open Access  
Data     Open Access   (Followers: 4)
Data Curation Profiles Directory     Open Access   (Followers: 6)
Dhaka University Journal of Science     Open Access  
Diálogos Interdisciplinares     Open Access  
Digithum     Open Access   (Followers: 2)
Discover Sustainability     Open Access   (Followers: 2)
Einstein (São Paulo)     Open Access  
Ekaia : EHUko Zientzia eta Teknologia aldizkaria     Open Access  
Elkawnie : Journal of Islamic Science and Technology     Open Access  
Emergent Scientist     Open Access  
Enhancing Learning in the Social Sciences     Open Access   (Followers: 7)
Enseñanza de las Ciencias : Revista de Investigación y Experiencias Didácticas     Open Access  
Entramado     Open Access  
Entre Ciencia e Ingeniería     Open Access  
Epiphany     Open Access   (Followers: 1)
Estação Científica (UNIFAP)     Open Access  
Ethiopian Journal of Education and Sciences     Open Access   (Followers: 5)
Ethiopian Journal of Science and Technology     Open Access  
Ethiopian Journal of Sciences and Sustainable Development     Open Access  
European Online Journal of Natural and Social Sciences     Open Access   (Followers: 4)
European Scientific Journal     Open Access   (Followers: 1)
Evidência - Ciência e Biotecnologia - Interdisciplinar     Open Access  
Exchanges : the Warwick Research Journal     Open Access   (Followers: 1)
Experimental Results     Open Access   (Followers: 1)
Facets     Open Access  
Fides et Ratio : Revista de Difusión Cultural y Científica     Open Access  
Fırat University Turkish Journal of Science & Technology     Open Access  
Fontanus     Open Access   (Followers: 1)
Forensic Science Policy & Management: An International Journal     Hybrid Journal   (Followers: 233)
Frontiers for Young Minds     Open Access  
Frontiers in Climate     Open Access   (Followers: 4)
Frontiers in Science     Open Access   (Followers: 1)
Fundamental Research     Open Access  
Futures & Foresight Science     Hybrid Journal   (Followers: 1)
Gaudium Sciendi     Open Access  
Gazi University Journal of Science     Open Access  
Ghana Studies     Full-text available via subscription   (Followers: 15)
Global Journal of Pure and Applied Sciences     Full-text available via subscription  
Global Journal of Science Frontier Research     Open Access   (Followers: 1)
Globe, The     Full-text available via subscription   (Followers: 4)
HardwareX     Open Access  
Heidelberger Jahrbücher Online     Open Access  
Heliyon     Open Access  
Himalayan Journal of Science and Technology     Open Access  
History of Science and Technology     Open Access   (Followers: 2)
Hoosier Science Teacher     Open Access  
Impact     Open Access   (Followers: 1)
Indian Journal of History of Science     Hybrid Journal  
Indonesian Journal of Fundamental Sciences     Open Access  
Indonesian Journal of Science and Mathematics Education     Open Access   (Followers: 2)
Indonesian Journal of Science and Technology     Open Access  
Ingenieria y Ciencia     Open Access   (Followers: 1)
Innovare : Revista de ciencia y tecnología     Open Access  
Instruments     Open Access  
Integrated Research Advances     Open Access  
Interciencia     Open Access  
Interface Focus     Full-text available via subscription  
International Annals of Science     Open Access  
International Archives of Science and Technology     Open Access  
International Journal of Academic Research in Business, Arts & Science     Open Access  
International Journal of Advanced Multidisciplinary Research and Review     Open Access  
International Journal of Applied Science     Open Access  
International Journal of Basic and Applied Sciences     Open Access   (Followers: 1)
International Journal of Computational and Experimental Science and Engineering (IJCESEN)     Open Access  
International Journal of Culture and Modernity     Open Access  
International Journal of Engineering, Science and Technology     Open Access  
International Journal of Engineering, Technology and Natural Sciences     Open Access  
International Journal of Innovation and Applied Studies     Open Access   (Followers: 3)
International Journal of Innovative Research and Scientific Studies     Open Access   (Followers: 1)
International Journal of Network Science     Hybrid Journal   (Followers: 3)
International Journal of Recent Contributions from Engineering, Science & IT     Open Access  
International Journal of Research in Science     Open Access   (Followers: 1)
International Journal of Social Sciences and Management     Open Access   (Followers: 2)
International Journal of Technology Policy and Law     Hybrid Journal   (Followers: 7)
International Letters of Social and Humanistic Sciences     Open Access  
International Scientific and Vocational Studies Journal     Open Access  
InterSciencePlace     Open Access  
Investiga : TEC     Open Access  
Investigación Joven     Open Access  
Investigacion y Ciencia     Open Access   (Followers: 1)
Iranian Journal of Science and Technology, Transactions A : Science     Hybrid Journal  
iScience     Open Access   (Followers: 1)
Issues in Science & Technology     Free   (Followers: 8)
Ithaca : Viaggio nella Scienza     Open Access  
J : Multidisciplinary Scientific Journal     Open Access  
Jaunujų mokslininkų darbai     Open Access  
Journal de la Recherche Scientifique de l'Universite de Lome     Full-text available via subscription  
Journal of Advanced Research     Open Access   (Followers: 2)
Journal of Al-Qadisiyah for Pure Science     Open Access  
Journal of Alasmarya University     Open Access  
Journal of Analytical Science & Technology     Open Access   (Followers: 4)
Journal of Applied Science and Technology     Full-text available via subscription   (Followers: 1)
Journal of Applied Sciences and Environmental Management     Open Access   (Followers: 1)
Journal of Big History     Open Access   (Followers: 3)
Journal of Composites Science     Open Access   (Followers: 3)
Journal of Diversity Management     Open Access   (Followers: 4)
Journal of Indian Council of Philosophical Research     Hybrid Journal  
Journal of Institute of Science and Technology     Open Access  
Journal of Integrated Science and Technology     Open Access  
Journal of King Saud University - Science     Open Access  
Journal of Mathematical and Fundamental Sciences     Open Access  
Journal of Natural Sciences Research     Open Access   (Followers: 1)
Journal of Negative and No Positive Results     Open Access  
Journal of Responsible Technology     Open Access  
Journal of Science (JSc)     Open Access  
Journal of Science and Engineering     Open Access   (Followers: 1)
Journal of Science and Technology     Open Access   (Followers: 2)
Journal of Science and Technology     Open Access   (Followers: 1)
Journal of Science and Technology (Ghana)     Open Access   (Followers: 3)
Journal of Science and Technology Policy Management     Hybrid Journal   (Followers: 1)
Journal of Science Foundation     Open Access   (Followers: 1)
Journal of Science of the University of Kelaniya Sri Lanka     Open Access  
Journal of Scientific Research     Open Access  
Journal of Scientific Research and Reports     Open Access  
Journal of Scientometric Research     Open Access   (Followers: 20)
Journal of Shanghai Jiaotong University (Science)     Hybrid Journal  
Journal of Social Science Research     Open Access   (Followers: 2)
Journal of Taibah University for Science     Open Access  
Journal of the Asiatic Society of Bangladesh, Science     Open Access  
Journal of the Ghana Science Association     Full-text available via subscription   (Followers: 3)
Journal of the History of Ideas     Full-text available via subscription   (Followers: 133)
Journal of the Indian Institute of Science     Hybrid Journal   (Followers: 3)
Journal of the National Science Foundation of Sri Lanka     Open Access  
Journal of the Royal Society of New Zealand     Hybrid Journal   (Followers: 48)
Journal of the South Carolina Academy of Science     Open Access  
Journal of Unsolved Questions     Open Access  
Jurnal Ilmiah Ilmu Terapan Universitas Jambi : JIITUJ     Open Access  
Jurnal Matematika, Sains, Dan Teknologi     Open Access  
Jurnal MIPA     Open Access  
Jurnal Natural     Open Access  
Jurnal Sains Dasar     Open Access  

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Jurnal Natural
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 1411-8513 - ISSN (Online) 2541-4062
Published by Universitas Syiah Kuala Homepage  [19 journals]
  • Seed size selection from M3 mutant soybean offspring of Kipas Merah Bireun
           variety in Aceh province

    • Authors: ZUYASNA ZUYASNA, M. ADIE MUCHLISH, EFENDI EFENDI, ZURAIDA ZURAIDA
      Pages: 1 - 6
      Abstract: Kipas Merah Bireun is one of the superior soybeans which was once widely cultivated in Bireun Regency, Aceh Province, used to be as a centre of origin of Kipas Merah Bireun variety. The weaknesses of the Kipas Merah Bireun variety are relatively small seed size (dry weight 12 g/100 seeds), long harvest period and less resistance to drought stress. Therefore it is necessary to improve the quality of Kipas Merah Bireun variety soybeans in order to get soybeans with better properties, one way is to use mutation techniques. The objectives of the study reported here were to evaluate the genetic variability for seed size of single plant selection for large seed in the mutants of gamma irradiated population. The research successfully selected 41 lines soybean mutant with both of high weight seed per plant and large seed size. Several mutant lines of Kipas Merah Bireun were promising to be investigated and developed further in accordance with attempts to increase productivity in Aceh province. Therefore, further research is needed to see how the growth and production of selected mutant soybeans with large seeds in this study in various locations and planting seasons.
      PubDate: 2022-02-26
      DOI: 10.24815/jn.v22i1.18189
      Issue No: Vol. 22, No. 1 (2022)
       
  • Application of PLS SEM in Evaluations of Mathematics Statistics II Course
           Online Learning

    • Authors: IZZATI RAHMI, MAHDHIVAN SYAFWAN, HAZMIRA YOZZA, IQBAL HAMONANGAN, FRILIANDA WULANDARI
      Pages: 7 - 16
      Abstract: The impact of the COVID-19 pandemic on the education sector includes the learning system that cannot be conducted directly (offline). With the change in the learning system, it is necessary to evaluate whether the implemented online learning system can run well and provide results as expected. The level of student satisfaction is one of the factors that can be used to evaluate online learning. This study analyzed the student satisfaction level with online learning for the Mathematics Statistics II course at the Mathematics Department of Andalas University, related to service quality by lecture and the level of student understanding. Data analysis was conducted using causal modeling, namely Partial Least Square Structural Equations Modeling (PLS-SEM). By using The PLS-SEM, it is known that there is a significant and positive effect of service quality on student satisfaction in the Mathematics Statistics II course. In addition, the service quality also affects the understanding level significantly and positively. However, the level of student understanding has no significant effect on the level of student satisfaction. The coefficient of determination (R2) from the structural model of student satisfaction toward the Mathematics Statistics II course online learning is 0.774. This value indicates that the resulting model is good because it has relatively high accuracy.
      PubDate: 2022-02-26
      DOI: 10.24815/jn.v22i1.23065
      Issue No: Vol. 22, No. 1 (2022)
       
  • Optimizing the gonadal performance of broodstock Helostoma temminckii with
           addition of enrichment ingredients in feed

    • Authors: INDIRA FITRILIYANI, SISWANTO SISWANTO, LUCHAS LUCHAS
      Pages: 17 - 24
      Abstract: The problem in the development of Kissing gourami fish culture was quality seeds that cannot be available continuously. Purpose of this research was to examine the need for additional enrichment materials in feed that can optimize the process of gonad maturation of Kissing gourami fish. Treatment A=Commercial feed added with Vegetable Oil, Glutathione, and Egg White; B=Commercial feed added with Vegetable Oil, Vitamin E 300 mg/Kg, Glutathione, and Egg White; C=Commercial feed added with Vegetable Oil, Vitamin E 500 mg/Kg, Glutathione, and Egg White. and D=Commercial feed added with Vegetable Oil, Vitamin E 700 mg/Kg, Glutathione, and Egg White. The results showed that all treatments with the addition of glutathione and vitamin E fortifications with levels of 300 mg-700 mg gave the effect of increasing IGS, IHS, higher fecundity and larger egg diameter than treatment A. The amount of initial IGS increase in treatment A was 33.49%, treatment B was 172.52%, treatment C was 208.60% and treatment D was 691.20%. While the IHS value at the end of the study decreased in treatment A by 35.30% and treatment C which also experienced a decrease in IHS by 26.23%. While in treatments B and D there was a not too large increase, in the range of 42.56% (B) and 5.66% (D).
      PubDate: 2022-02-26
      DOI: 10.24815/jn.v22i1.23426
      Issue No: Vol. 22, No. 1 (2022)
       
  • Potential of carbon storage and sequestration in the Heroes Park City
           Forest, Purworejo Regency, Central Java

    • Authors: VIVI ASTUTI, INGGITA UTAMI, SRI WAHYUNINGSIH
      Pages: 25 - 30
      Abstract: Heroes Park City Forest has  a high vegetation density in Purworejo Regency, Central Java province, absorbing and storing carbon from the atmosphere. This study analyzes the value of carbon stock, sequestration, and tree composition in the Heroes Park City Forest. Data collection was carried out in February 2021, using three randomly distributed 20 x 100 m plots. Analysis of carbon stock data, important value index, and diversity index was carried out quantitatively descriptively. The results showed that the carbon stock value of trees was 116.84 tons ha-1, which according to Reducing Emissions from Deforestation and Forest Degradation or REDD+, was included in the high carbon stock category. The value of carbon sequestration in Heroes Park urban forest is 428.80 tons ha-1, which is higher than some city forests in Indonesia. The sampling location is covered with 157 tree species, dominated by Acacia auriculiformis, and has a moderate level of tree diversity. Vegetation dominated by Acacia auriculiformis from Fabaceae contributed 43 percent of the total carbon stock in Heroes Park. Abiotics such as rainfall, air temperature, and humidity in Purworejo City support the growth of plants from the Fabaceae. Therefore, Heroes Park City Forest in Purworejo Regency has high carbon storage or carbon stock and sequestration values and needs to be monitored annually to maintain this potential.
      PubDate: 2022-02-26
      DOI: 10.24815/jn.v22i1.21798
      Issue No: Vol. 22, No. 1 (2022)
       
  • Anatomical changes of Ipomoea reptans due to mercury uptake and
           accumulation in contaminant soil

    • Authors: NITA TAUHIDA, ESSY HARNELLY, MUHAMMAD NASIR, MUHAMMAD BAHI
      Pages: 31 - 35
      Abstract: Heavy metal contaminants like mercury is a serious problem to human, animals, and some plants’ health. Phytoremediation is an alternative technique, which can remediate the contaminants from soil using a hyperaccumulator plant. The goal of this research was to study anatomical changes of plant main organs (roots, stems, and leaves) of  Ipomoea reptans which are assumed as a hyperaccumulator plant that grows in mercury contaminant. The mercury concentration of the growth medium was 0, 61.871, 92.258, and 107.046 ppb. Ipomoea reptans were harvested after 27 days. The anatomical changes of the plant’s main organs were observed by preparing the cross-section of roots, stems, and leaves of I. reptans. The result showed that mercury treatment has caused anatomical damage at the xylem vessel of the root, and decreased bulliform cell size. The anatomical damage was found only in the root of I. reptans. The mercury concentration in media decrease to 0 ppb (P0), 50,420 ppb (P1), 58,583 (P2), and 96,120 (P3).
      PubDate: 2022-02-26
      DOI: 10.24815/jn.v22i1.23198
      Issue No: Vol. 22, No. 1 (2022)
       
  • Virulence of conidia Beauveria bassiana (Bals.) as a bioinsecticide
           against Crocidolomia pavonana (F.) (Lepidoptera: Pyralidae) on broccoli
           plants

    • Authors: MUHAMMAD SAYUTHI, ALFIAN RUSYDI, HASNAH HASNAH, NAILA EVI AZAHRA
      Pages: 36 - 43
      Abstract: Crocidolomia pavonana is an important pest of broccoli plants. Pest control is currently still using chemical pesticides that negatively impact the environment. It is hoped that Beauveria bassiana will become one of the environmentally friendly bioinsecticides. The research aimed to study the virulence level of conidia density of B. bassiana as a bioinsecticide against C. pavonana pests on broccoli plants. This experiment used a completely randomized design consisting of 5 treatments and four replications so that 20 experimental units were obtained. The Basic Plant Protection Laboratory and Plant Pest Science Laboratory Faculty of Agriculture, Syiah Kuala University as the research location, which was carried out from January to September 2021. The parameters observed were larval mortality, pupae formed, imago appeared, an incubation period of B. bassiana conidia, and average time of C. pavonana. The results showed that B. bassiana with conidia density of 108/mL distilled water was effective as a bioinsecticide against C. pavonana. The highest percentage of C. pavonana mortality observed at 6 Days After Application (DAA) occurred at a density of 108 conidia/mL of water (97.50%), and the lowest was at a density of 102 conidia/mL of distilled water (62.50%). The percentage of pupae formed was observed. At 7, DAA was 15% using a density of 102 conidia /mL aquadest. Produce 5%, a density of 104 conidia/mL of distilled water was used. The percentage of imago that appeared with a conidia density of 102/mL of distilled water killed at 14 DAA yielded 15%, and 5% resulted from a density of 104 conidia/mL of distilled water. The fastest incubation occurred at a density of 108 conidia/mL of distilled water with a time of 3.50 days. Death of C. pavonana at 3.03 days required conidia density of B. bassiana 102/mL of distilled water.
      PubDate: 2022-02-26
      DOI: 10.24815/jn.v22i1.22628
      Issue No: Vol. 22, No. 1 (2022)
       
  • Influence of monomer concentration on the morphology, contact angle, water
           uptake, and antibacterial activity of grafted cellulose obtained from peel
           durian

    • Authors: ROSLIANA LUBIS, SAISA SAISA
      Pages: 44 - 50
      Abstract: The objective of the current study is to evaluate and determine the effect of monomer concentration of ClAETA on the grafting copolymerization of oxidized cellulose which isolated from peel durian. Four concentrations of ClAETA were used in this study, e.g., 40, 50, 60, and 70%. Several analyses were performed to determine the material characteristic, e.g., degree of grafting, FT-IR, surface morphology, contact angle, degree of swelling, and antibacterial activity. The result showed, monomer concetration plays a significant role to the physical and surface morphology of DAC-ClAETA. The degree of grafting of ClAETA was found in the range of 15-31%, and at the concentration of 50% the grafted oxidized cellulose has 30.4% of degree of grafting. SEM images showed the pore volume has linear correlation to the monomer concetration, it increased the surface roughness. Also, the contact angle confirmed the hydrophilicity and degree of swelling of grafted oxidized cellulose was increase that linear to ClAETA concentration. DAC-g- ClAETA was found antibacterial active against S. aureus, S. epidermis, and C. albicans than DAC.
      PubDate: 2022-02-26
      DOI: 10.24815/jn.v22i1.23865
      Issue No: Vol. 22, No. 1 (2022)
       
  • Optimization of fuzzy entropy on solar panel’s motor

    • Authors: MUHAMMAD IKHWAN, MARWAN RAMLI, MARDLIJAH MARDLIJAH
      Pages: 51 - 56
      Abstract: Renewable energy has been in great demand by the public, even some countries have set regulations for substitution and transition from fossil energy to renewable energy. This study aims to modify the fuzzy control system with a metaheuristic method, namely fuzzy entropy. The entropy value of the fuzzy set in the previous stage becomes the basis for calculating the foot of uncertainty in the new fuzzy set. This process makes the entropy method parallel to other optimization methods that have been carried out on fuzzy control systems. The results obtained indicate that the modified fuzzy control system successfully controls the angle and angular velocity of the solar panel. The error value shown is very small and the time to reach stability is below 5 s. This is a rapid development of several previous studies. The modified system has no overshoot and steady state error below 1%. Based on these results, entropy research can be developed again by changing the fuzzy set to a more complex form.
      PubDate: 2022-02-26
      DOI: 10.24815/jn.v22i1.23187
      Issue No: Vol. 22, No. 1 (2022)
       
  • Anticancer activity and apoptotic induction of Chromolaena odorata Linn
           leaves extract and fractions on hepatocellular carcinoma cell lines
           (HepG2)

    • Authors: HANIFAH YUSUF, MARHAMI FAHRIANI
      Pages: 57 - 67
      Abstract: The purpose of this study is to screen and to evaluate anticancer activity and apoptosis induction of Chromolaena odorata (C. odorata) leaves extract and its fractions on HepG2 cancer cell lines. The C. odorata leaves were extracted by maceration using ethanol 80% then fractionated by using n-hexane, ethyl acetate and ethanol. MTT assay method was used to evaluate anticancer activity and flowcytometri method used to evaluate the induction of apoptosis. The phytochemical analysis and  characterization of the major compound of the extract and the fractions were done by using Liquid Chromatography-Mass Spectroscopy (LCMS). The phytochemical analyis showed that the crude ethanolic extract and fractions of C. odorata leaves contains alkaloid, flavonoids, phenolic, steroids, tannin and saponin. The result of LCMS shown the major compounds of the extract and fractions are 5,7,8,3′,4′-Pentamethoxyflavonone, 1-Carboethoxy-β-carboline, 3-Methylcanthin-2, 6- dion, Canthin-6-one. In the n-hexane fraction obtained 5,7,8,3′,4′-Pentamethoxyflavonone, Methyl ophiopogonanone A and Pd-C-Ⅱ. Meanwhile, in the ethyl acetate fraction contained, 3-(3′,4′-Dihydroxybenzyl)-7-hydroxychroman-4-one, 3-(4'-Hydroxy-benzyl)-5,7-dihydroxy-6-methyl-8- methoxy-chroman-4-one, Methyl opiopogonanone A and Sinensetin. The ethanol fraction, contained the compound 3-(3′,4′-Dihydroxybenzyl)-7-hydroxychroman-4-one, 3-(4'-Hydroxy-benzyl)-5,7-dihydroxy-6-methyl-8- methoxy-chroman-4-one and Methyl opiopogonanone A. The crude ethanolic extract, n-hexane fraction, ethyl acetate and ethanol fraction extract have anticancer activities with IC50 value of 23.44 mg/mL, 84.52mg/mL; 88.51mg/mL; and 167.49 mg/mL respectively. This research suggests the crude ethanolic extract of Chromolaena odorata leaves has a potential candidate for hepatocarcinoma treatment.
      PubDate: 2022-03-08
      DOI: 10.24815/jn.v22i1.22854
      Issue No: Vol. 22, No. 1 (2022)
       
 
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