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  Subjects -> SCIENCES: COMPREHENSIVE WORKS (Total: 426 journals)
Showing 1 - 200 of 265 Journals sorted alphabetically
AAS Open Research     Open Access   (Followers: 2)
ABC Journal of Advanced Research     Open Access  
Academic Voices : A Multidisciplinary Journal     Open Access   (Followers: 2)
Accountability in Research: Policies and Quality Assurance     Hybrid Journal   (Followers: 22)
Acta Materialia Transilvanica     Open Access  
Acta Nova     Open Access   (Followers: 1)
Acta Scientifica Malaysia     Open Access   (Followers: 1)
Acta Scientifica Naturalis     Open Access   (Followers: 3)
Adıyaman University Journal of Science     Open Access  
Advanced Science     Open Access   (Followers: 13)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 10)
Advanced Theory and Simulations     Hybrid Journal   (Followers: 5)
Advances in Research     Open Access  
Advances in Science and Technology     Full-text available via subscription   (Followers: 17)
African Journal of Science, Technology, Innovation and Development     Hybrid Journal   (Followers: 8)
Afrique Science : Revue Internationale des Sciences et Technologie     Open Access   (Followers: 2)
AFRREV STECH : An International Journal of Science and Technology     Open Access   (Followers: 4)
American Academic & Scholarly Research Journal     Open Access   (Followers: 6)
American Journal of Applied Sciences     Open Access   (Followers: 27)
American Journal of Humanities and Social Sciences     Open Access   (Followers: 15)
ANALES de la Universidad Central del Ecuador     Open Access   (Followers: 3)
Anales del Instituto de la Patagonia     Open Access  
Applied Mathematics and Nonlinear Sciences     Open Access   (Followers: 1)
Apuntes de Ciencia & Sociedad     Open Access  
Arab Journal of Basic and Applied Sciences     Open Access  
Arabian Journal for Science and Engineering     Hybrid Journal   (Followers: 5)
Archives Internationales d'Histoire des Sciences     Partially Free   (Followers: 6)
Archives of Current Research International     Open Access  
ARO. The Scientific Journal of Koya University     Open Access  
ARPHA Conference Abstracts     Open Access   (Followers: 6)
ARPHA Proceedings     Open Access   (Followers: 5)
ArtefaCToS : Revista de estudios sobre la ciencia y la tecnología     Open Access   (Followers: 1)
Asia-Pacific Journal of Science and Technology     Open Access  
Asian Journal of Advanced Research and Reports     Open Access   (Followers: 2)
Asian Journal of Applied Science and Engineering     Open Access   (Followers: 2)
Asian Journal of Scientific Research     Open Access   (Followers: 3)
Asian Journal of Technology Innovation     Hybrid Journal   (Followers: 7)
Australian Field Ornithology     Full-text available via subscription   (Followers: 4)
Australian Journal of Social Issues     Hybrid Journal   (Followers: 7)
Avances en Ciencias e Ingeniería     Open Access  
AZimuth     Full-text available via subscription   (Followers: 2)
Bangladesh Journal of Scientific Research     Open Access   (Followers: 1)
Beni-Suef University Journal of Basic and Applied Sciences     Open Access   (Followers: 3)
Berichte Zur Wissenschaftsgeschichte     Hybrid Journal   (Followers: 10)
Berkeley Scientific Journal     Full-text available via subscription  
BIBECHANA     Open Access   (Followers: 2)
BibNum     Open Access  
Bilge International Journal of Science and Technology Research     Open Access   (Followers: 1)
Bioethics Research Notes     Full-text available via subscription   (Followers: 16)
Bistua : Revista de la Facultad de Ciencias Básicas     Open Access  
BJHS Themes     Open Access   (Followers: 1)
Black Sea Journal of Engineering and Science     Open Access  
Borneo Journal of Resource Science and Technology     Open Access  
Brazilian Journal of Science and Technology     Open Access   (Followers: 2)
Bulletin de la Société Royale des Sciences de Liège     Open Access  
Bulletin of the National Research Centre     Open Access  
Butlletí de la Institució Catalana d'Història Natural     Open Access  
Central European Journal of Clinical Research     Open Access  
Chain Reaction     Full-text available via subscription  
Ciencia & Natura     Open Access   (Followers: 1)
Ciencia Amazónica (Iquitos)     Open Access   (Followers: 1)
Ciencia en Desarrollo     Open Access   (Followers: 2)
Ciencia en su PC     Open Access   (Followers: 1)
Ciencia Ergo Sum     Open Access  
Ciência ET Praxis     Open Access  
Ciencia y Tecnología     Open Access  
Ciencia, Docencia y Tecnología     Open Access  
Ciencias Holguin     Open Access   (Followers: 2)
CienciaUAT     Open Access   (Followers: 1)
Citizen Science : Theory and Practice     Open Access   (Followers: 2)
Communications Faculty of Sciences University of Ankara Series A2-A3 Physical Sciences and Engineering     Open Access  
Communications in Applied Sciences     Open Access  
Comprehensive Therapy     Hybrid Journal   (Followers: 3)
Comunicata Scientiae     Open Access   (Followers: 1)
ConCiencia     Open Access  
Conference Papers in Science     Open Access   (Followers: 2)
Configurations     Full-text available via subscription   (Followers: 10)
COSMOS     Hybrid Journal  
Crea Ciencia Revista Científica     Open Access   (Followers: 2)
Cuadernos de Investigación UNED     Open Access  
Current Issues in Criminal Justice     Hybrid Journal   (Followers: 15)
Current Research in Geoscience     Open Access   (Followers: 8)
Dalat University Journal of Science     Open Access  
Data     Open Access   (Followers: 4)
Data Curation Profiles Directory     Open Access   (Followers: 4)
Dhaka University Journal of Science     Open Access  
Dharmakarya     Open Access  
Diálogos Interdisciplinares     Open Access  
Digithum     Open Access   (Followers: 2)
Discover Sustainability     Open Access   (Followers: 3)
Einstein (São Paulo)     Open Access  
Ekaia : EHUko Zientzia eta Teknologia aldizkaria     Open Access  
Elkawnie : Journal of Islamic Science and Technology     Open Access  
Emergent Scientist     Open Access  
Enhancing Learning in the Social Sciences     Open Access   (Followers: 9)
Enseñanza de las Ciencias : Revista de Investigación y Experiencias Didácticas     Open Access  
Entramado     Open Access  
Entre Ciencia e Ingeniería     Open Access   (Followers: 1)
Epiphany     Open Access   (Followers: 4)
Episteme Transversalis     Open Access  
Ergo     Open Access  
Estação Científica (UNIFAP)     Open Access   (Followers: 1)
Ethiopian Journal of Education and Sciences     Open Access   (Followers: 6)
Ethiopian Journal of Science and Technology     Open Access  
Ethiopian Journal of Sciences and Sustainable Development     Open Access   (Followers: 6)
European Online Journal of Natural and Social Sciences     Open Access   (Followers: 12)
European Scientific Journal     Open Access   (Followers: 10)
Evidência - Ciência e Biotecnologia - Interdisciplinar     Open Access  
Exchanges : the Warwick Research Journal     Open Access   (Followers: 2)
Experimental Results     Open Access   (Followers: 1)
Extensionismo, Innovación y Transferencia Tecnológica     Open Access   (Followers: 3)
Facets     Open Access  
Fides et Ratio : Revista de Difusión Cultural y Científica     Open Access   (Followers: 1)
Fırat University Turkish Journal of Science & Technology     Open Access  
Fontanus     Open Access  
Forensic Science Policy & Management: An International Journal     Hybrid Journal   (Followers: 373)
Frontiers for Young Minds     Open Access  
Frontiers in Climate     Open Access   (Followers: 3)
Frontiers in Science     Open Access   (Followers: 1)
Futures & Foresight Science     Hybrid Journal   (Followers: 4)
Gaudium Sciendi     Open Access   (Followers: 1)
Gazi University Journal of Science     Open Access  
Ghana Studies     Full-text available via subscription   (Followers: 15)
Global Journal of Pure and Applied Sciences     Full-text available via subscription  
Global Journal of Science Frontier Research     Open Access   (Followers: 2)
Globe, The     Full-text available via subscription   (Followers: 4)
HardwareX     Open Access  
Heidelberger Jahrbücher Online     Open Access  
Heliyon     Open Access  
Himalayan Journal of Science and Technology     Open Access   (Followers: 1)
History of Science and Technology     Open Access  
Hoosier Science Teacher     Open Access  
Iberoamerican Journal of Science Measurement and Communication     Open Access  
Impact     Open Access   (Followers: 2)
Indian Journal of History of Science     Hybrid Journal   (Followers: 1)
Indonesian Journal of Fundamental Sciences     Open Access  
Indonesian Journal of Science and Mathematics Education     Open Access   (Followers: 4)
Indonesian Journal of Science and Technology     Open Access  
Ingenieria y Ciencia     Open Access   (Followers: 1)
Innovare : Revista de ciencia y tecnología     Open Access  
Instruments     Open Access  
Integrated Research Advances     Open Access  
Interciencia     Open Access   (Followers: 1)
Interface Focus     Full-text available via subscription  
International Annals of Science     Open Access  
International Archives of Science and Technology     Open Access  
International Journal of Academic Research in Business, Arts & Science     Open Access   (Followers: 2)
International Journal of Advanced Multidisciplinary Research and Review     Open Access  
International Journal of Advancement in Education and Social Sciences     Open Access   (Followers: 1)
International Journal of Advances in Engineering, Science and Technology     Open Access   (Followers: 3)
International Journal of Applied Science     Open Access  
International Journal of Basic and Applied Sciences     Open Access   (Followers: 4)
International Journal of Computational and Experimental Science and Engineering (IJCESEN)     Open Access  
International Journal of Culture and Modernity     Open Access  
International Journal of Engineering, Science and Technology     Open Access  
International Journal of Innovation and Applied Studies     Open Access   (Followers: 12)
International Journal of Innovative Research and Scientific Studies     Open Access   (Followers: 6)
International Journal of Innovative Research in Social and Natural Sciences     Open Access   (Followers: 2)
International Journal of Network Science     Hybrid Journal   (Followers: 3)
International Journal of Recent Contributions from Engineering, Science & IT     Open Access   (Followers: 1)
International Journal of Research in Science     Open Access   (Followers: 2)
International Journal of Science & Emerging Technologies     Open Access   (Followers: 1)
International Journal of Sciences : Basic and Applied Research     Open Access  
International Journal of Social Sciences and Management     Open Access   (Followers: 3)
International Journal of Technology Policy and Law     Hybrid Journal   (Followers: 7)
International Letters of Social and Humanistic Sciences     Open Access   (Followers: 1)
International Review of Applied Sciences     Open Access  
InterSciencePlace     Open Access   (Followers: 1)
Investiga : TEC     Open Access  
Investigación Joven     Open Access  
Investigación Valdizana     Open Access  
Investigacion y Ciencia     Open Access   (Followers: 1)
Iranian Journal of Science and Technology, Transactions A : Science     Hybrid Journal  
iScience     Open Access   (Followers: 1)
Issues in Science & Technology     Free   (Followers: 7)
Istituto Lombardo - Accademia di Scienze e Lettere - Rendiconti di Scienze     Open Access  
Ithaca : Viaggio nella Scienza     Open Access  
J : Multidisciplinary Scientific Journal     Open Access  
Jaunujų mokslininkų darbai     Open Access  
Journal de la Recherche Scientifique de l'Universite de Lome     Full-text available via subscription   (Followers: 2)
Journal for New Generation Sciences     Open Access   (Followers: 3)
Journal of Chromatography & Separation Techniques     Open Access   (Followers: 12)
Journal of Advanced Research     Open Access   (Followers: 3)
Journal of Al-Qadisiyah for Pure Science     Open Access   (Followers: 1)
Journal of Alasmarya University     Open Access  
Journal of Analytical Science & Technology     Open Access   (Followers: 6)
Journal of Applied Science and Technology     Full-text available via subscription   (Followers: 1)
Journal of Applied Sciences and Environmental Management     Open Access   (Followers: 3)
Journal of Big History     Open Access   (Followers: 3)
Journal of Composites Science     Open Access   (Followers: 3)
Journal of Critical Thought and Praxis     Open Access   (Followers: 2)
Journal of Deliberative Mechanisms in Science     Open Access  
Journal of Diversity Management     Open Access   (Followers: 6)
Journal of Indian Council of Philosophical Research     Hybrid Journal  
Journal of Institute of Science and Technology     Open Access  
Journal of Integrated Science and Technology     Open Access  
Journal of Interaction Science     Open Access   (Followers: 1)
Journal of Kerbala University     Open Access   (Followers: 1)
Journal of King Saud University - Science     Open Access   (Followers: 1)
Journal of Law, Information and Science     Full-text available via subscription   (Followers: 20)

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Beni-Suef University Journal of Basic and Applied Sciences
Number of Followers: 3  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2314-8535 - ISSN (Online) 2314-8543
Published by SpringerOpen Homepage  [260 journals]
  • Evaluation of terpene-rich extract of Lantana camara L. leaves for
           antimicrobial activity against mycobacteria using Resazurin Microtiter
           Assay (REMA)

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Shriniwas P. Patil, Subhash T. Kumbhar BackgroundLantana camara L. (Verbenaceae) is notorious weed, leaves of which are rich in terpenes, in the form of essential oil. Terpenes have potent antimicrobial and antimycobacterial activities. Depending upon saponification characteristic of lipids and waxes; unsaponified petroleum ether extract which contain only terpenes, can be prepared. Terpene-rich extract (TRE) of L. camara L. leaves has exhibited higher antioxidant and antimicrobial activities as compared to any solvent extract.AimPresent attempt was aimed towards preparation of terpene-rich extract (TRE) of L. camara L. leaves; its phytochemical analysis by NMR and evaluation of its anti-mycobacterial activity.MethodsIn order to retain only terpenes in extract, in present study, petroleum ether extract of L. camara L. leaves was saponified using aqueous potassium hydroxide and remaining unsaponified extract (TRE) was phytochemically analyzed using chromatographic and NMR techniques. Further, TRE was screened for its anti-mycobacterial potential against Mycobacterium tuberculosis (H37Ra) by Resazurin Microtiter Assay (REMA) method.ResultsDetail phytochemical analysis reflected successful preparation of extract rich in terpenes. H1-NMR analysis proved the presence of various terpenes and triterpenoids, reported earlier for their presence in the plant. TRE was then found to have significant anti-mycobacterial activity with MIC90 value up to 50 µg/ml.ConclusionTRE contains different terpenes in specific proportion which makes it significantly potent antimycobacterial with minimum MIC90 value up to 50 µg/ml. REMA found to be economic and easier as compared to other techniques.Graphical abstractGraphical abstract for this article
       
  • Catalytic upgrading of bio-oil from bagasse: Thermogravimetric analysis
           and fixed bed pyrolysis

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): M.U. Garba, Umaru Musa, A.G. Olugbenga, Yahaya S. Mohammad, Mohammed Yahaya, A.A. Ibrahim The objective of this work was to upgrade bio-oil from bagasse by pyrolysis using catalyst/biomass of three different compositions (5, 15 and 20 wt% HZSM-5 loadings). The thermal analysis and product distribution experiments were carried out in a thermogravimetric analyzer (TGA) and a fixed bed reactor, respectively. In TGA, the pyrolysis of catalytic runs shifted the thermograph curves to the lower temperatures and generated high yield residues compared to that obtained from non-catalytic run. From a fixed-bed condition, the maximum bio-oil yield from non-catalytic and catalytic runs at a temperature of 500 °C at 15% ZSM-5 catalyst concentration were 49.4% and 21.1 wt% respectively. Aromatics, phenols and oleic acids are the main chemical components deduced from gas chromatography/mass spectrometry (GC–MS) analysis of the bio-oil. Bio-oil from catalytic pyrolysis had more aromatics (desirable component) and less oleic acid (undesirable component) than the bio-oil from non-catalytic pyrolysis. The study of bio-oil from catalytic bagasse pyrolysis enhances desirable component when used as transportation fuel. Besides addition of catalyst improving the degradation mechanism of biomass also alters the product composition closer to the aromatic range hydrocarbon.
       
  • The hydrothermal uranium and some other metal deposits of the extensional
           faulting during the advanced opening of the Red Sea, Central Eastern
           Desert, Egypt

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Soliman Abu Elatta Abdallah Mahmoud, Gehad Mohammed Reda Mansour The hydrothermal uranium and some other metal deposits occur within the zone of the major NW-SE trending normal fault and its associated minor normal faults that cut the Miocene clastic-carbonate sediments at Ochre-Um Greifat and Wadi Wizr locations. Samples from these locations were subjected to mineralogical and geochemical studies in order to determine their concentrations of strategic and economic elements (e.g., U, Th, Mo, Zn, Pb, As and V) as well as their petrogenesis. The mineralogical studies were confirmed by X-ray diffraction (XRD) and the environmental scanning electron microscopy coupled with energy dispersive spectroscopy ESEM/EDX. The geochemical data was determined by ICP-MS and ICP-OES (Acme Lab. of Canada). The results showed that the Ochre-Um Greifat deposits are enriched in U and Zn elements, with significant concentrations of Cu and Th while Wadi Wizr deposits are enriched in Mo, Zn, Pb and As elements. The discrimination diagrams based on major and trace elements indicated that the Ochre-Um Greifat and Wadi Wizr deposits are of hydrothermal origin. Additionally, uranium deposit was subjected to the supergene processes. Moreover, radionuclides showed that the state of disequilibrium as a result of physicochemical conditions of the hydrothermal solutions and the nature of ambient rocks. The study concluded that the locations need further geological and geophysical studies to determine if nuclear materials (uranium and molybdenum) and other associated elements are economically valuable.Graphical abstractGraphical abstract for this article
       
  • Comparative life-cycle cost and GHG emission analysis of five different
           water heating systems for residential buildings in Australia

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Nallapaneni Manoj Kumar, Mobi Mathew In this paper, five different types of water heating systems namely electric instantaneous, electric storage, natural gas instantaneous, natural gas storage, and heat pump are studied for Australian conditions. The study is carried out for understanding the life cycle cost of each system under similar water demand conditions. The focus is made on life-cycle cost (LCC) that include the running costs on an annual basis, and total running cost for the system life, maintenance cost; and greenhouse gas (GHG) emissions. The observations reveal that five systems had major differences in the upfront cost, running cost, and life-cycle cost, and GHG emissions. The observed LCC and GHG emissions for electric instantaneous, electric storage, natural gas instantaneous, natural gas storage, and heat pump are 9005 AU$, 12,724 AU$, 6955 AU$, 7479 AU$, and 8098 AU$, and 1862 tons of CO2, 2306 tons of CO2, 851 tons of CO2, 917 tons of CO2, and 842 tons of CO2 respectively.
       
  • Biochemical markers for carbon sequestration in two mangrove species
           (Avicennia marina and Rhizophora mucronata)

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Kandasamy Kathiresan, Kandasamy Saravanakumar, Nabikhan Asmathunisha, Raj Anburaj, Venugopal Gomathi In order to find the simple biochemical markers for selection of mangrove clones with high carbon sequestration, This work was made in two species (Rhizophora mucronata and Avicennia marina) under two seasons by analysing the carbon sequestration rate in mangrove biomass, in relation to 15 biochemical fractions- carotenoids, anthocyanins, flavonoids, phenols, tannins, leaf wax, chloroplast, chlorophylls (a, b, a/b, total) and chloroplasts. Carbon sequestration rate was positively correlated with chlorophyll a, b, total, flavonoids, leaf surface wax and chlorophyll an of the chloroplast. Anyone of these biochemical markers is suggested for selecting the mangrove clones of high carbon sequestration potential.
       
  • Overtopping breach peak outflow approximation of embankment dam by using
           Monte Carlo method

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Mohamed Mohamed Abdellatif Mohamed The main goal of this paper is to develop an empirical relationship for estimating the peak outflow discharge of embankment dam breach due to overtopping flow. The main controlling parameter in the previously developed relationships is the reservoir volume behind the embankment dam. These relationships assumed that the whole reservoir volume becomes empty during the failure process and the area under the outflow hydrograph curve is equal to this volume. Conducted large scale physical models recorded that a remaining vertical head-cut in the upstream side of the embankment dam maintained even after the final breach formation. That means, the previously depended upon assumption is not true especially for embankments constructed from cohesive soils. The newly developed relationship accounts for the remaining vertical head-cut and the spelled overtopping flow. The Monte Carlo method was employed to calculate the area under the flow duration curve and consequently the development of the new formula. The new relationship gave more accurate results and reasonable outcomes as compared to actual previous case sttudies measured breach peak outflow discharges and the results obtained using previously developed formulae.
       
  • In vitro and in vivo evaluation of anti-inflammatory potency of Mesua
           ferrea, Saraca asoca, Viscum album & Anthocephalus cadamba in murine
           macrophages raw 264.7 cell lines and Wistar albino rats

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Syed Murthuza, B.K. Manjunatha The present study reports the in-vitro and in-vivo anti-inflammatory potency of Mesua ferrea, Saraca asoca, Viscum album and Anthocephalus cadamba, potent medicinal plants of Western Ghats of Karnataka India. Lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cell line was used in in-vitro assay. Pretreatment with methanolic extracts at non toxic concentrations abridged the LPS-induced protein levels. Among the four plants tested, methanolic extract of Viscum album (70.20 ± 1.094) and Mesua ferrea (68.29 ± 2.862) showed potent anti-inflammatory activity at 100 µg concentration with an IC50 value of 57.23 ± 1.922 and 63.36 ± 3.791 µg/ml. In vivo anti-inflammatory activity was evaluated using carrageenan-induced paw edema in Wistar albino rats, Viscum album (0.6167 ± 0.01667) and Mesua ferrea (0.6833 ± 0.01667) showed potent anti-inflammatory activity (at 100 mg/kg.bw). The obtained results indicate the potency of active constituents of Mesua ferrea and Viscum album in the development of effective anti-inflammatory drugs.
       
  • Computational studies on α-aminoacetamide derivatives with
           anticonvulsant activities

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Oluwaseye Adedirin, Adamu Uzairu, Gideon A. Shallangwa, Stephen E. Abechi Computational methods were used to study the structural parameters that influence that anticonvulsant activity of some α-aminoacetamides which were active in maximal electroshock seizure test. Their molecular structures were optimized with B3LYP/631G** density function theory method using Spartan 14 software. Modified-K-mediod clustering algorithm was used for data division, genetic function algorithm was used for variable selection and multiple linear regressions method was used for model construction. Developed model was statistically significant with coefficient of determination (R2) of 0.957, cross-validated R2 i.e. Q2 of 0.927, variance ratio (F4,15) of 82.94, Y-randomization R2 i.e. cR2P of 0.840 and predicted R2 (R2Pred) of 0.812. The molecular descriptors contained in the model were GATS8c (Geary autocorrelation of lag-8/weighted by atomic charges); VCH-7 (valence chain of order 7); VE3_D (Logarithmic coefficient sum of the last eigenvector from topological distance matrix) and RDF100p (radial distribution function − 100/weighted by polarizability). Molecular docking result showed that studied compounds had high binding affinity for neuronal sodium channel (PDB: 2KaV). Their binding affinity compared favorably with that of phenytoin, a validated sodium channel blocker. In addition, a linear relationship existed between anticonvulsant activity of studied compounds and their binding affinity for neuronal sodium channel.
       
  • A method to attain power optimality and efficiency in solar panel

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): M. Rajvikram, S. Leoponraj One of the renewable energy resources, solar is obtained from the solar radiations. The solar radiations are converted into electrical energy through the photovoltaic panel. The electrical yield of solar panel is mainly affected by optical and thermal losses which are caused due to reflection and temperature variations. These temperature and reflective variations also reduce the lifetime of the panel. The main intention of this work is to use anti-reflective coatings to increase the efficiency of the solar cell by increasing the electrical yield through increasing the output power and thus causing a reduction in optical losses. The antireflective chemicals like aluminum oxide and tantalum pentoxide (Al2O3- Ta2O5-Al2O3) are coated as a double layer. A very thin film of the chemicals is deposited on the large area of 156 mm × 156 mm at the surface of the solar cell. By this method, the reflection loss has been reduced and efficiency has been increased. The FLIR thermal image is also included in this paper for the comparison of the results of uncoated and coated solar panel. This method is cost effective as the chemical agents used are economical which is advantageous compared to other methods.
       
  • Blockchain: Enabling wide range of services in distributed energy system

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Nallapaneni Manoj Kumar This paper reports on how the technology behind cryptocurrency (Bitcoin) i.e. Blockchain could offer its services in distributed energy system (DES), noting on the issues related to operating conditions, energy generation monitoring, energy sharing and trading, financial flows, emission inventory, carbon emission trading and many more. Information on blockchain implication in DES is reported.
       
  • Approach towards different fermentative techniques for the production of
           bioactive actinobacterial melanin

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Poonam Sharma, Tanim Arpit Singh, Bhanupriya Bharat, Sheetal Bhasin, H.A. Modi Actinobacteria were isolated from soil samples gathered from different localities of Indore region. Among 64 isolates, 28 exhibited pigment production. These isolates were further assessed in secondary screening by submerged fermentation process. The isolate NL was found to be the highest pigment producer. Cultural and Morphological characteristics of our isolate NL corresponded with typical features of Streptomycetes. Maximum pigment production was observed on peptone yeast extract iron medium (PYI). Pigment yield was highest using cotton method when compared against solid state and submerged fermentation processes. The influence of heavy metal salts on pigment production was tested and results revealed that Co, Cu and Pb increased the pigment production whereas Mn was found to have inverse effect. Antibacterial activity of crude melanin obtained from different fermentative processes was checked against test organisms Escherichia coli, Salmonella typhi, Bacillus subtilis and Staphylococcus aureus. The crude melanin recovered from cotton method and submerged fermentation exhibited broad spectrum activity against gram positive and gram negative organism. Optimised pigment production using the enhancing heavy metals can be scaled up to industrial level for production of pigments to be employed as preservatives and dyes.
       
  • Heavy metal tolerance and adaptability assessment of indigenous
           filamentous fungi isolated from industrial wastewater and sludge samples

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Pawan Kumar Rose, Rani Devi A total of twenty-five isolates of fungi from the wastewater and sludge samples of a steel industry were screened for their resistance to Cu(II) and Ni(II). Three strains were finally selected and identified as Aspergillus awamori, Aspergillus flavus and Aspergillus niger. The growth behavior and concurrent bioaccumulation of Cu(II) and Ni(II) by each fungus was investigated as a function of pH of the growth medium and concentration of Cu(II) and Ni(II). pH for maximum growth with concurrent bioaccumulation of Cu(II) and Ni(II) was observed, respectively as 4.0 and 5.0 for A. awamori, 5.0 and 5.0 for A. flavus and 4.0 and 5.0 for A. niger. The growth behavior with increasing heavy metals concentration was also examined as tolerance index. Synergistic and inhibitory effect on growth with lower and higher concentration of both heavy metals, respectively observed for each fungus. Our finding indicates that the resistant strains isolated from their contaminated habitat have better pertinence and application in heavy metals bioremediation.
       
  • Semicarbazide-sensitive amine oxidase activity levels in patients with
           acute lymphoblastic leukemia after cytotoxic chemotherapy

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Shatha Abdul Wadood AL‑Shammaree BackgroundThe role of Semicarbazide-sensitive amine oxidase (SSAO) in carcinogenesis is unknown; however, due to its function it may be involved in tumorigenesis via production of reactive aldehydes and hydrogen peroxide.ObjectiveThe study aimed to assess serum SSOA activity and to investigate the effect of cytotoxic chemotherapy on liver function in patients with acute lymphoblastic leukemia (ALL).Materials and MethodsSamples from 25 children with ALL were taken before and after finishing the induction phase of chemotherapy with (Daunorubicin, Vincristine VRC, L-asparaginase, Cyclophosphamide, Cytosar, Dexon, and Adriamycin). Activity of SSAO and liver function tests (alanine transferase (ALT), aspartate transferase (AST), alkaline phosphatase (ALP) and total serum bilirubin TSB) were measured using colorimetric methods before and after treatment.ResultsSignificant lower level in SSOA activity was found in 68% of the patients (P 
       
  • Acetone extract of Flammulina velutipes caps: A promising source of
           antioxidant and anticancer agents

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): C.I. Ukaegbu, S.R. Shah, A.H. Hazrulrizawati, O.R. Alara The high death rate associated with cancer has fuelled the search for complementary cancer treatment methods in recent times. Among the leading alternative methods is natural products which have attracted much attention due to their high body tolerance. In this study, the caps of Flammulina velutipes (commonly called Enoki), an edible mushroom, were extracted with different solvents and characterized for in vitro antioxidant and anticancer activities. The anticancer activity of the extract was studied against breast cancer cells (MCF-7 and MDA-MD-231) and normal or Vero breast cells (MCF-10a). The radical scavenging, metal reducing power, and anticancer properties of the extracts were investigated via in vitro chemical and cell-based methods. Furthermore, a phytochemical profiling process was performed on the extract fraction with the highest level of biological activities using Liquid chromatography-mass spectrometry coupled with quadrupole time of flight (LC-MS-QTof). The results showed acetone fraction of Enoki caps to exhibit more radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radicals (IC50 = 0.840 mg/mL) and hydrogen peroxide (H2O2) radicals (IC50 = 0.890 mg/mL) compared to the ethyl acetate fraction (IC50 = 0.97 mg/mL against DPPH and 1.180 mg/mL against H2O2). Additionally, acetone fraction showed a better metal reducing property in a concentration-dependent manner. The in vitro cytotoxicity study showed a preferential level of toxicity of the acetone extract to the studied cancer cell lines compared to the Vero cells. This extract showed more cytotoxicity against MCF-7 (IC50 value ranged from 17.7 µg/mL to 38.36 µg/mL) and MDA-MB-231 (IC50 value ranged from 114.5 µg/mL to 184.2 µg/mL) compared to MCF-10a (>250 µg/mL). These findings present F. velutipes caps as a potential natural source of antioxidant and anticancer agents.
       
  • Synthesis, characterization and the role of ionic radii on the mechanistic
           of solvothermal for polyazine PtIV complexes: Reduction PtIV to PtII, DFT,
           X-ray single crystal and anticancer studies

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Waleed H. Al-Assy, Said A.I. Mahmoud, Dalal Z. Husein, Mohsen M. Mostafa Polypyridyl based on triazine and pyrazine rings with Pt4+, including 2,4,6-tris(2-pyridyl)-1,3,5-triazine (TPT, L1) and 2,3,5,6-tetra(2-pyridyl)-1,4-triazine (TPP, L2), was reported. [Pt34+ (TPT)2Cl8]Cl4·2H2O (1) and [Pt4+(TPP)Cl3]Cl·3H2O (2) were synthesized and characterized. Comparative studies of the solvothermal of Pt4+ complexes and the stability studies of triazine and pyrazine moieties were investigated. Pt2+ complex, [PtII(bpca)Cl], resulted from the metal-promoted solvolysis of L1 to bis-(2-pyridylcarbonyl) amide anion (bpca) and 2-picolinamide, gives yellow single crystal, C12H8ClN3O2Pt (3). The effect of ionic radii of the metal ions has a vital role in solvolysis process. The single crystal shows a square-planar around the Pt2+ ion (3). Crystal data of 3: space group; a = 7.5263 (2) b = 14.1846 (4) c = 22.6884 (7) Å, α = β = γ = 90°, V = 2422.16 (12) Å3, Z = 8. The DFT parameters were calculated to confirm the geometry of complexes. Anticancer activity of complexes was measured.
       
  • Incidence and Molecular Identification of Cochliobolus carbonum as Causal
           Organism of Rice Seedling Blight

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Rabie A.S. El-Shafey, Kotb A. Attia, Fatma A. Mostafa, Rabab M. Elamawi During last few years, seedling blight and black lesions along culm of rice seedlings have been appearing frequently in nurseries. Identification of the causal organism was the objective of this research. The identification was done based on morpho-pathological characteristics and Internal Transcribed Spacer (ITS) region sequencing analysis. The pathogen effects on germination and development of rice seedlings were studied under laboratory and greenhouse conditions. Based on the morphological examination, 10 isolates were identified as Cochliobolus carbonum fungus. This organism recorded different levels of pathogenicity, and most of the isolates showed high virulence, up to 56% as seedling infection with isolate ECC-5. The germination percentage was reduced to 73% for cultivar Sakha 101. Sakha 101 recorded highest infected seedlings percentage (44%) under artificial inoculation. The isolates’ reaction was more variable on seedlings than on leaves of Egyptian rice cultivars. Infection severity on leaves of isolate ECC-5 recorded highest average for infection, while isolate ECC-3 did not exhibit any infection. Most of C. carbonum isolates were induced severe infection on rice seedlings. Therefore, the identified isolates were recorded as a novel pathogen causing seedling blight disease on rice. Soaking in crude extract filtrate of C. carbonium isolates culture reduced germination percentage to 1.55% with Sakha101 and inhibit the shoots and roots growth. The molecular variation using ISJ markers reflected a high level of genetic variation between isolates. The ITS region sequencing of two isolates ECC-7 and ECC-9 was successfully analyzed, and alignment with 19 isolates of Bipolaris zeicola worldwide with 97% identity. Phylogenetic analyses of sequences resulted in a well-resolved phylogeny. The data suggested that ITS region analysis was a potential tool for phylogenetic reconstruction of the new isolates and as was DNA barcode for identification of the fungal species. It confirmed that this organism is a rice seed-borne pathogen that causes seedling blight disease.
       
  • Design, synthesis of novel azo derivatives of benzimidazole as potent
           antibacterial and anti tubercular agents

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Sujit Kumar Mohanty, Anuradha Khuntia, N. Yellasubbaiah, C. Ayyanna, B. Naga Sudha, M. Sai Harika A series of some novel azo derivatives of benzimidazole were prepared by coupling diazonium derivative of benzimidazole with various appropriate aromatic compounds. Confirmation of the chemical structure of the novel synthesized compounds 6a (1–5) & 6b (1–5) was substantiated by TLC, different spectral data IR, 1H NMR, Mass spectra and elemental analysis. The synthesized compounds were evaluated for in-vitro antimicrobial and anti tubercular activities against Bacillus subtilis, Escherichia coli and Mycobacterium tuberculosis. The compounds exhibited weak, moderate, or high in-vitro antimicrobial and anti tubercular potency. Compounds 6a2, 6a3, 6b2 and 6b3 exhibited potential antimicrobial activity.Graphical abstractWhere, 2a: 5-Iodo Salicylic acid & 2b: 3-bromo-5-hydroxy benzoic acidAr: 1-5Graphical abstract for this article
       
  • Ceramide generation as a novel biological mechanism for chemo-preventive
           and cytotoxic effects of hesperidin on HT-144 melanoma cells

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Mahdi Mashhadi Akbar Boojar, Masoud Mashhadi Akbar Boojar, Sepide Golmohammad, Mojtaba Nikkhah Yazdi IntroductionHesperidin and its aglycone, hesperetin are abundant natural flavonoid in Citrus and known for their anti-neoplastic and pro-apoptotic properties. Ceramide is a key regulator in apoptosis and cytotoxicity and its metabolizing enzymes have considered as a target in cancer studies. Acid ceramidase (ACDase) and Neutral sphingomyelinase (NSMase) are the main enzymes in ceramide metabolism.MethodsIn the present study, we investigated the effects of hesperidin and hesperetin on HT-144 human melanoma cells. The investigated cells treated with seven different concentrations of hesperidin and hesperetin (0–210 µM) and cell viability, caspase-3 and 9 activities, total cell ceramide and the activities of ACDase and NSMase were evaluated with fluorescence and spectrophotometry analysis.ResultsThe data revealed that hesperidin and hesperetin were induced cytotoxicity and activities of caspase-3 and 9 in a dose-dependent fashion (P 
       
  • Cultural optimization of a new exopolysaccharide producer
           “Micrococcus roseus

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Faten Hereher, Amira ElFallal, Mohammed Abou-Dobara, Elshahat Toson, Mohamed M. Abdelaziz The ability to produce polysaccharides is widely spread among bacteria. The usefulness of EPS molecules makes development of new strategies for improved synthesis of EPS is a necessity. A novel EPS Producer promisingly was obtained from a culture of Micrococcus roseus. In the present investigation, two screening steps for exopolysaccharide production were done using 9 strains and 7 isolates of different taxonomic bacterial groups isolated from different soil samples together with bacterial strains obtained from culture collections. The first screening for EPS-production was done on solid basal media based on the mucous aspect of colonies. The slimiest and mucous bacterial strains were again screened for EPS production in liquid cultures. Comparative data of the eleven bacterial strains showed that Micrococcus roseus proved to produce the maximum EPS in shacked culture and the maximum EPS production was amounting to 1.805 g EPS/l. An attempt was made to optimize and maximize the production of EPS by M. roseus. Maximum EPS production of 800 mg/100 ml observed after 96 h incubation at 25 °C using 4.5% and 0.02% of sucrose and ammonium sulphate concentration respectively at pH 7.0. A preliminary structural elucidation of the exopolysaccharide of M. roseus was done using spectroscopic technique FTIR and showed a characteristic band attributed to (1–3) β glucan linkage. The monomeric composition was glucose, galactose and rhamnose with two carbohydrate and protein portions 91.3% and 8.7% respectively.
       
  • Evaluation of optimization parameters in microwave reflux extraction of
           piperine-oleoresin from black pepper (Piper nigrum)

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Olusegun Abayomi Olalere, Nour Hamid Abdurahman, Rosli bin Mohd Yunus, Oluwaseun Ruth Alara, Sweeta Akbari Black pepper is a functional plant with nutritional and medicinal benefits. Piperine being the major bioactive compound in black pepper has been applied for the treatment of many free radical-related diseases. This study determined a combination of operating parameters that optimize the microwave extraction of the piperine oil. The effect of irradiation time, microwave power level, feed particle size and feed-solvent ratio on piperine content and absorbed microwave energy were tested using a three-level L9-Taguchi parametric design. The results obtained placed the optimum extraction condition at 90 min of irradiation time, 350 W of microwave power, 0.1 mm of particle size and 1:12 of feed-solvent ratio. Under this optimal condition the optimal piperine oil and absorbed microwave energy of 5.64 w/w and 84.17 J/min were obtained, respectively. The optimal conditions can therefore be employed to design extraction process with higher efficiency and productivity.
       
  • Pathogenicity of Escherichia coli O157 in commercial broiler
           chickens

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Azza A. EL-Sawah, AL Hussien M. Dahshan, El-Shaymaa El-Nahass, A.I. Abd El-Mawgoud Broiler chickens are frequently infected with Escherichia coli (E. coli), which often results in disease and high economic losses. The most affected ages to infections with E. coli are chickens from 4 to 5 weeks. Several studies show that poultry are already and persistently infected by E. coli O157. The current study aimed to determine the pathogenicity of E. coli serogroup O157 in broiler chicks, a trial of prevention and treatment using probiotic and/or antibiotic. The chicks were divided into five groups including control negative, control positive, probiotic treated group, probiotic and antibiotic treated group and finally antibiotic treated group. The clinical signs, mortality, performance parameters, postmortem examination, re-isolation and E. coli count as well as the pathological changes in liver and intestine were recorded. The probiotic group gave the best results in controlling infection by E. coli O157 followed by probiotic and antibiotic and finally antibiotic. In conclusion, the E. coli O157 serogroup was pathogenic to chicks when experimentally inoculated, so particular attention must be directed toward E. coli O157 not only as a pathogen infecting bird but also of great public health impact. Also probiotics was of great value in protection against the E. coli infection and improve the performance parameters of chicks.
       
  • Comparative morphological study of three species of Saraca L. (Fabaceae)
           by the statistical approach to find out the logic of potent morphological
           markers

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Sujit Sil, Tanmoy Mallick, Kalyan Kumar De, Arabinda Pramanik, Asok Ghosh The genus Saraca L. (Fabaceae s.l.) has 11 species among which three are distributed in India. This study is done for these three species as S. indica L., S. declinata (Jack) Miq., and S. thaipingensis Cantley ex Prain which are taxonomically recognized and identified by morphological characters, both of vegetative and reproductive. As a common trend of taxonomic study key to the identification of taxa is based on contrast pairs of lead characters considering as good characters to the taxonomic work when these characters are different in different taxa. The present study is emphasized here again to find out the marker characters for identity with the approach of preparation of ternary plot considering 82 characters through statistical method. Morphological characters like the texture of ovary, the presence of hood on anther and distribution of hairs on anther, bract and stigma morphology, shape and size of the seed, pollen surface etc. are found to be potent morphological markers for these three species of Saraca. The marker character to prepare a better key of identity is also established by this method. Earlier works on taxonomy also support this finding. The results show the relationship and character correlation amongst the species as S. declinata is more close to S. thaipingensis than S. indica. This work approaches a basis to strengthen a part of classical taxonomy.
       
  • Clerodendrum volubile P. Beauv (Lamiaceae), an underutilized indigenous
           vegetable of utmost nutritive and pharmacological importance

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Abdulwakeel Ayokun-nun Ajao, Ojo Michael Oseni, Olaniran Temitope Oladipo, Yusuf Agbomekhe Adams, Yusuf Ola Mukaila, Abdulwadud Abiodun Ajao Clerodendrum volubile is an underutilized vegetable native to West Africa most especially Nigeria. The plant is used traditionally in the treatment of arthritis, diabetes, dropsy, gout rheumatism, dropsy, swellings, oedema, and analgesic. The ethnopharmacological potential of C. volubile through its phytochemistry, biological activities, and proximate analysis was reviewed for the first time. Published articles on C. volubile were sourced from scientific data bases such as Google Scholar, Medicine, PubMed, Science Direct, and Scopus. C. volubile contains appreciable quantity of phytochemicals and compounds such as ajugoside, pectolinarigenin, protocatechuic acid, biochanin, and 5, 7,4′-Trimethoxykaempferol. It also elicited wide range of biological activities such as antidiabetic, antihyperlipidemic, anti-hypertension, antioxidant, anticancer, anti-inflammatory, hepatoprotective, antimicrobial, and analgesic. C. volubile is a potential pharmaceutical agent especially in the treatment of cancer due to the ability of its extracts to scavenge reactive oxygen species. Future research should focus on isolation of bioactive compounds responsible for elicited activities and mechanism of action of the bioactivities through in vivo studies.
       
  • Two spectrophotometric methods for quantitative determination of some
           pesticides applied for cucumber in Egypt

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Amira M. Hegazy, Rehab M. Abdelfatah, Hamada M. Mahmoud, Mohamed A. Elsayed Specific spectroscopic techniques were validated for assay of four pesticides applied for cucumber in Egypt; mandipropamid (MAN), metalaxyl (MET), thiophenate methyl (THO) and carbendazim (CAR). First method is derivative method for the quaternary mixture of the studied pesticides; by using the first derivative THO was assayed at 281 nm, while MAN and CAR were assayed using second derivative at 236.4 and 256.2 nm, respectively and MET was assayed using third derivative at 221.6 nm. Second method is double divisor ratio spectrum derivative method that used for assay of MAN at 289 nm and MET at 233.2 nm using a double divisor of 30 μg mL−1 of each of THO and CAR, then both THO and CAR were determined at 259 and 267.4 nm, respectively, using a double divisor of 4 μg mL−1 of each of MAN and MET. The obtained results were within the acceptable range regarding to the Egyptian committee of agricultural recommendations.
       
  • A novel chalcone derivative from Punica granatum peel inhibits
           LOX/COX enzyme activity

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Sudheesh S., Soumya K., Jesna James The present study evaluates the Lipoxygenase (LOX) and cyclooxygenase (COX) inhibitory activity of a flavonoid isolated from Punica granatum peel. The molecular structure and chemical bonds were analyzed using UV–Visible, FT-IR, 1H NMR and Mass spectra. The structure of the compound was identified as a novel derivative of chalcone. The isolated compound was interpreted as (2E)-3-(4-hydroxy-3-pentylphenyl)-1-(2-hydroxy-4,5-di((E)-prop-1-enyl)phenyl)prop-2-en-1-one. A prominent inhibition on LOX and COX was observed. The in vitro study indicates the potential of isolated compound to use as an anti-inflammatory agent.
       
  • Assessment of proliferative index in different grades of breast cancers
           using AgNOR (Agyrophilic Nuclear Organizer Region) expression

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Williams Kweku Darkwah, Gideon Aidoo, Yanhui Ao, Kwabena Owusu Danquah, Ernest Adjei, Ernest Adankwah, Alhassan Kadri Nucleolar organiser regions (NORs) are loops of DNA which are responsible for ribosomal RNA (rRNA) transcription in the nucleus of cells. NORs can be selectively stained by silver methods. The NORs agyrophilia is due to a group of nucleolar proteins, which have affinity for silver (Agyrophilic Nucleolar Organizer Regions, AgNOR proteins). The aim of the present study is to assess proliferative index in different grades of invasive ductal carcinoma (IDC) by using AgNOR as a marker. A total of 18 formalin fixed paraffin-embedded breast tissue blocks were retrieved from the archives of the histopathology department of the Komfo Anokye Teaching Hospital, Ghana. The tissue blocks included 17 IDC, (with 8 as grade 2 IDC, 9 as grade 3 IDC) and 1 normal breast tissues. Tissue sections were diagnosed and graded following haematoxylin and eosin (H&E) staining. Silver staining was used to demonstrate the presence of AgNOR. The AgNOR dots were manually counted in 50 and 100 cells. The mean AgNOR count (mAgNOR) and proliferative index, (pAgNOR, percentage of cells with ≥5 AgNOR dots per nucleus), significantly increased with increasing grade of IDC. The mAgNOR and pAgNOR were low in normal breast, (at p-value less than 0.05). There was no significant difference in the mAgNOR and pAgNOR score for counting 50 and 100 cells (at a p-value of 0.01). mAgNOR and pAgOR increases with increase in grade of IDC and hence can be used to assess proliferative index of IDC.
       
  • Synthesis, characterization and the role of ionic radii on the mechanistic
           of solvothermal for polyazine PtIV complexes: Reduction PtIV to PtII, DFT,
           x-ray single crystal and anticancer studies

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Waleed H. Al-Assy, Said A.I. Mahmoud, Dalal Z. Husein, Mohsen M. Mostafa Polypyridyl based on triazine and pyrazine rings with Pt4+, including 2,4,6-tris(2-pyridyl)-1,3,5-triazine (TPT, L1) and 2,3,5,6-tetra(2-pyridyl)-1,4-triazine (TPP, L2), was reported. [Pt34+ (TPT)2Cl8]Cl4·2H2O (1) and [Pt4+(TPP)Cl3]Cl·3H2O (2) were synthesized and characterized. Comparative studies of the solvothermal of Pt4+ complexes and the stability studies of triazine and pyrazine moieties were investigated. Pt2+ complex, [PtII(bpca)Cl], resulted from the metal-promoted solvolysis of L1 to bis-(2-pyridylcarbonyl) amide anion (bpca) and 2-picolinamide, gives yellow single crystal, C12H8ClN3O2Pt (3). The effect of ionic radii of the metal ions has a vital role in solvolysis process. The single crystal shows a square-planar around the Pt2+ ion (3). Crystal data of 3: space group; a = 7.5263 (2) b = 14.1846 (4) c = 22.6884 (7) Å, α = β = γ = 90°, V = 2422.16 (12) Å3, Z = 8. The DFT parameters were calculated to confirm the geometry of complexes. Anticancer activity of complexes was measured.
       
  • Response surface optimization and effects of agricultural wastes on total
           petroleum hydrocarbon degradation

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Kingsley Amechi Ani, Ebere Ochin This study was carried out to investigate the effects of Goat manure (GM) and Palm oil mill effluent (POME) on total petroleum hydrocarbons (TPHs) degradation. Microbial respiration rates (CO2 evolution) were investigated. TPHs degradation rate constants were estimated using the first-order kinetics model. Scanning electron microscope (SEM) and infrared spectroscopy (FT-IR) were used to investigate the surface morphologies and functional groups in GM and POME. The CO2 evolution rates in TPH contaminated soil treated with GM (TPHCS-GM), TPH contaminated soil treated with POME (TPHCS-POME), and the untreated TPH contaminated soil (UTPHCS) were 497 mg/g, 440 mg/g, and 296 mg/g, respectively. TPHCS-GM showed higher TPH degradation rate with corresponding lower half-lives. Results from the physiochemical characterization indicated that GM performed better in restoring the scarce nutrient in the TPH contaminated soil. 58% and 39% of TPH were degraded at pH 8 and 4 in TPHCS-GM and TPHCS-POME, respectively. The response surface optimization process indicated the accuracy of the quadratic model (R2 value of 0.9891) in predicting TPH degradation (76.59%) with optimum independence variables of initial TPH concentration (300 g/L) and pH (6). The results obtained from this work showed the positive prospects of GM and POME as organic nutrients in TPH contaminated soil.
       
  • A review on Adenium obesum: A potential endemic medicinal plant
           in Oman

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Md. Amzad Hossain Medicinal plants have played a vital role in the treatment of various human diseases and development of the society since the ancient times. Medicinal plants are the only safe sources for new drugs to treat curable and incurable diseases. About 25% of the prescription drugs available worldwide are derived from natural resources. Adenium obesum (AO) is one of the rare endemic medicinal plants in Oman and it belongs to family Apocynaceae. A biochemical investigation of the local AO species showed that the selected plant contained different groups of chemical compounds such as carbohydrate, cardiac glycoside, flavonoid, prenylated flavonoids, terpenoids, pregnanes etc. In addition, the pharmacological activities on the selected Omani species showed significant antimicrobial, antioxidant, anticancer, antiviral and immune modulatory activities. Only a few scientific research has been performed on the indigenous AO plant species. For this reason, it is mandatory for human, mainly the young generation to be aware of the toxicity, biochemical and pharmacological activities of the selected AO plant species. This comprehensive review report of the selected medicinal plant includes taxonomy, biological activity, phytochemicals, and potential uses. The study concludes that the plant extracts or isolated phytochemicals might be used as safe novel medicine in the near future for therapy and prevention of different diseases in the near future.
       
  • Uranium potentiality mapping of G-V occurrence at Gabal Gattar area, North
           Eastern Desert, Egypt, using GIS approach

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Mohamed A. El Zalaky Delineation and evaluation of mineral resources are major exploration parameters required for investment decisions. Identifying the best probable sites for uranium mineralization in terrains of lack subsurface penetrations is a challenging task. In northern part of Egyptian Eastern Desert, the uranium occurrences of Gabal Gattar area are among the most important source of uranium mineralization. Gattar-V (G-V) uranium occurrence considered as the most important uranium locality in the northern parts of Gabal Gattar area. The well-known uranium mineralization in this occurrence is restricted to the geological contact zone between the Hammamat sedimentary rocks and the G. Gattar Alkali feldspar granite. The lithological units and their alteration zones that are associated with the uranium mineralization and the ground spectrometric measurements data are identified and delineated throughout the field work of the geological investigation. In addition to the delineation of visible uranium mineralized zones, useful aid for the location of uranium promising zones is provided. Uranium potential (UP) mapping is a systematic tools that considers the main controlling factors which influence the localization of uranium mineralization within their host rocks. The present study aims to highlight, identify, model and map uranium promising zones in G-V uranium occurrence by using Geographic Information System (GIS) to construct multiple geological thematic maps such as different kind of alteration, contact zone, radiometric measurement and secondary zones of uranium mineralization. The constructed thematic maps of the different controlling factors of U-mineralization are assigned with a fixed score, weight, and calculated using a linear equation approach. Each weighted thematic map is statistically calculated to produce a uranium potential levels map of the investigated area. The uranium potential areas thus obtained were classified into four classes of potentiality (very high, high, moderate and low). The obtained an integrated uranium potential map of the investigated area will be a useful guide in the mining planning activity and create a good decision for better planning and management of uranium resource.
       
  • Plackett-Burman design for screening of process components and their
           effects on production of lactase by newly isolated Bacillus sp. VUVD101
           strain from Dairy effluent

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Abraham Peele Karlapudi, S. Krupanidhi, Rajeswara Reddy E., Indira M., N. Bobby Md., Venkateswarulu T.C. In the present investigation, a low-cost fermentation medium was designed to achieve the maximum production of lactase from the Bacillus sp. VUVD101 strain through the screening of different nutritional and physical variables, using the Plackett-Burman design. Fourteen variables of the fermentation process were selected: incubation time, temperature, pH, RPM, DO, inoculum size, inoculum age, MgSO4, l-Cysteine, KH2PO4, CaCl2, K2PHO4, corn steep liquor and lactose. The selected variables were evaluated through statistical analysis, based on their significance, coefficient value and standard effect plot. The results suggested that six variables, namely, corn steep liquor, lactose, MgSO4, temperature, pH and RPM, had influence with high confidence levels, while the remaining eight variables did not show a significant effect on production. The analysis of the variance value R2 (0.96) also showed the model used for prediction to be significant (p less than 0.05). The plot for the standard effect for each component and its traits provided accurate data by which to select well-suited variables for further optimization. In comparison with the basal medium, 68% higher enzyme activity was achieved from the model of the optimized medium, and lactase activity was found to be 18.31 U/ml.
       
  • Molecular detection of integron and antimicrobial resistance genes in
           multidrug resistant Salmonella isolated from poultry, calves and human in
           Beni-Suef governorate, Egypt

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Sahar A. Abdel Aziz, Gihan K. Abdel-Latef, Salama A.S. Shany, Sherin R. Rouby Antibiotic resistant Salmonella represent a public health threat worldwide. The current study was delineated to determine Salmonella spp. prevalent in poultry droppings (N: 14 flocks), calves feces (N: 90) and human stool samples (N: 80) from live-stock contacts as well as poultry handler in Beni-Suef governorate, Egypt. Phenotypic and genotypic screening for the presence of antimicrobial resistance was applied. Isolation rates were 57.1%, 5.6% and 2.5% for poultry, calves and humans, respectively. S. Megherafelt. S. Kentucky, S. Amsterdam, S. Nigeria, S. Paratyphi: B2, S. Alamo, S. Madras and S. Haifa were the predominant serovars in poultry flocks under investigation. The predominant serovar from calves’ samples was S. Kentucky while S. Infantis and S. Paratyphi: B2 were detected in human samples. The results of antimicrobial disc diffusion revealed the presence of multiple drug resistance (MDR) in100% of Salmonella isolates. PCR confirmed the existence of class 1 integron and the following gene cassettes in the resistant strains, blaTEM and blaSHV for β-lactams, aadA2 for aminoglycosides (streptomycin), tetA and tetB for tetracycline, sull for Sulfamethoxazole, dfrA for trimethoprim, floR for chloramphenicol and mphA for macrolides.
       
  • An analytical study of the performance indices of air spring suspensions
           over the passive suspension

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): M.M. Moheyeldein, Ali M. Abd-El-Tawwab, K.A. Abd El-gwwad, M.M.M. Salem In terms of vehicle dynamics aspects, the suspension system should maintain good ride quality and road holding performance against the road irregularities especially in the case of high driving speeds. In this paper, two different air spring models (classic air spring; dynamic air spring model) are presented. Thereafter, both the dynamic air spring suspension and the passive suspension are compared in terms of RMS of body acceleration, suspension travel, and dynamic tire force. Based on that, a 2-DOF quarter mathematical model is implemented in MATLAB/Simulink platform. The ride quality and road handling responses are evaluated considering a vehicle speed of 20 m/s and road Class C. Besides, a parametric analysis is conducted to investigate the influences of the air spring model parameters on the vehicle dynamics. Then, the results are analyzed and compared for both the classic and dynamic air spring models showing the improvements over the passive suspensions. Furthermore, time domain and frequency domain analysis are then presented for the proposed suspensions. The obtained results indicated that, for the dynamic air spring model, the body acceleration, suspension travel and dynamic tire load improved by 27%, 10%, and 20%, respectively, which provides more comfort and easy handling performances comparing to the passive suspension.
       
  • Effect of intranasal insulin on peripheral glucose profile in
           dexamethasone-induced insulin resistance in Wistar rats

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Anoka A. Njan, Chloe O. Fatigun, Abdul-Musawwir Alli-Oluwafuyi, Olufunke E. Olorundare, Olarenwaju S. Afolabi, Olugbenga Akinola, Abdulbasit Amin This study evaluates the therapeutic potential of intranasal insulin (INI) in dexamethasone-induced insulin resistance in Wistar rats. In the first phase of the study, thirteen, healthy, untreated male Wistar rats were divided into 2 groups and administered either vehicle (0.9% Normal saline, 20 µl) or insulin (2 IU) intranasally to assess intranasal delivery of insulin in brain. In the second phase of experiments, to evaluate the acute effects of intranasal insulin on peripheral blood glucose, intranasal or intraperitoneal insulin was co-administered with or without dexamethasone 10 mg/kg to 26 male Wistar rats and blood glucose monitored. To evaluate effect of intranasal insulin in peripheral metabolic disease model, insulin or vehicle was administered via intranasal or intraperitoneal (IP) route to control or dexamethasone (Dex)-treated (0.5 mg/kg, IP) female Wistar rats for seven consecutive days. Twenty-four hours after last dose, trunk blood was collected via cardiac puncture. Biochemical assay of glucose, lipid and insulin was performed on serum while enzyme activity – glucokinase and glucose-6-phosphatase (G6Pase) or lactate dehydrogenase (LDH) and glucose-6-phosphate dehydrogenase (G6PDH) were assayed from liver and brain homogenates respectively. Acute intranasal but not intraperitoneal insulin elevated brain insulin after 30 min. In animals administered single dose of 10 mg/kg dexamethasone, intranasal and intraperitoneal insulin lowered blood glucose within one hour. However, only the former’s effect was maintained at the 3rd and fourth hour. Dex-induced hyperglycemia was associated with increased hepatic glucose-6-phosphatase activity and decreased high-density lipoprotein (HDL), these effect were attenuated by subchronic (INI) administration. Also INI did not induce oxidative stress in the brain which suggests no brain damage during the period of study. Subchronic administration of INI was able to reduce the effect of Dex-induced hyperglycemia that is associated with increased hepatic glucose-6-phosphatase activity and decreased high-density lipoprotein (HDL) without damage to the brain. We demonstrate the potential of brain targeting with intranasal insulin in a rat model of insulin resistance and peripheral metabolic disease.
       
  • Pilot study: Tumor suppressive effect of crude polysaccharide substances
           extracted from some selected mushroom

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Faten Hereher, Amira ElFallal, Elshahat Toson, Mohammed Abou-Dobara, Mohamed Abdelaziz A number of bioactive molecules, including antitumor substances, have been identified in many mushroom species. Polysaccharides are the best known and most potent mushroom derived substances with antitumor and immunomodulating properties. The present study is a pilot study was conducted to evaluate the role of these polysaccharide substances as antitumor agents using EAC cell line in animal mice. Five mushroom species were used as a source of these polysaccharide substances. These are Pleurotus pulmonarius, Pleurotus sajar caju, Pleurotus sp. Ganoderma applanatum and Volvariella speciosa. An extremely significant reduction of the tumor volumes in tumor bearing mice treated with most of these substances was noticed compared with those saline-treated tumor-bearing mice. This reduction in tumor volume was accompanied with a significant reduction in both liver DNA and RNA in addition to an increase in total lipids and proteins. A significant increase in serum superoxide dismutase activity and a highly significant decrease in each of the serum alkaline phosphatase, GPT and GOT in addition to MDA. On the other hand, there was an elevation in albumin concentration after treatment the groups of tumor-bearing mice with the polysaccharide substances compared with those saline-treated tumor-bearing mice. The results showed that the administration of these polysaccharide via the prophylactic treatment don't rule out its role in the antitumor effect by these substances. However, the other mode of treatment i.e. treatment by polysaccharide after tumor injection showed better results in this respect. This means that not only these polysaccharides cure but have also important prophylactic properties. The presence of β-glucan in these polysaccharides was confirmed by FT-IR analysis.
       
  • Mellein, a dihydroisocoumarin with bioherbicidal activity from a new
           strain of Lasiodiplodia pseudotheobromae C1136

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Charles Oluwaseun Adetunji, Julius Kola Oloke, Mishra Pradeep, A. Peter Oluyori, Ravinder Singh Jolly, Oluwasesan Micheal Bello The use of synthetic herbicides poses a serious threat to environment, health and food safety. The development of safe and effective bioherbicides for selective control of weeds is thus the primary concern in crop production around the world. Efforts are being made to investigate the use of a safe, ecofriendly and highly selective herbicides from biological origin. Coumarin and its derivatives are natural compounds renowned for their phytotoxic potential.Mellein, a dihydroisocoumarin designated as (R)-8-hydroxy-3-methylisochroman-1-one was isolated as an active metabolite from the broth of a new strain (this strain is one of the best among phytopathogenic strains collected) of Lasiodiplodia pseudotheobromae. The structural characterization of the compound was achieved by using combined spectroscopic analysis i.e. 1D and 2D NMR and LC–MS. The host range study was carried-out against plants from Cucurbitaceae, Solanaceae and Leguminosae, Poaceae and Valerianaceae families, the isolated phytotoxic metabolite from Lasiodiplodia pseudotheobromae at a concentration 10 µg/µl showed selective inhibition at 56%–66% against the latter two families only when inoculated.Hence, purified compound from Lasiodiplodia pseudotheobromae is recommended for large scale production of bioherbicides for the management of weeds in conventional farming to improve yield and enhance food security.
       
  • Genotyping of β-lactams resistant staphylococci isolated from bovine
           subclinical mastitis

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Ahmed H. Abed, Al Sayed R. Attia, Ahmed A. Atia Staphylococci are one of the most significant causative mastitis pathogens in both clinical and subclinical cases. The present study aimed to study the prevalence of staphylococcal subclinical mastitis studying their antibiogram and detection of the prevalence mecA and blaZ genes in β-lactams resistant isolates using polymerase chain reaction (PCR). A total of 433 Staphylococcus species were recovered from 493 subclinically mastitic quarters with a prevalence of 87.8%. S. aureus were the most prevalent isolates as 237 isolates (48%). Also, 196 Coagulase-Negative Staphylococci (CNS) isolates (39.8%); representing 8 species, were recovered of which S. xylosus was the most predominant (36.7%), followed by S. epidermidis (14.8%), S. chromogenes (13.3%), S. haemolyticus (11.2%) and S. saprophyticus (9.7%). Results of antimicrobial susceptibility testing showed high resistances against ampicillin and cefoxitin while a moderate resistance was recorded against amoxicillin. PCR was applied on 40 β-lactam resistant Staphylococcus isolates (20 S. aureus and 20 CNS) for detection of mecA and blaZ genes. The two genes were detected in 75% and 65% of S. aureus isolates as well as in 70% and 55% of CNS isolates, respectively.
       
  • Production of new rhamnolipids Rha C16-C16 by Burkholderia sp. through
           biodegradation of diesel and biodiesel

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): A.B. Abeer Mohammed, Ahmed A. Tayel, Nihal M. Elguindy Burkholderia sp. C3 was previously isolated from polycyclic aromatic hydrocarbons (PAH) contaminated soil; it was evaluated for the ability to utilize a range of diesel and biodiesel as sole carbon sources. Burkholderia sp. C3 could degrade 99% of diesel and biodiesel supplemented at 2% (v/v) in a basal mineral medium within 3 days of incubation at 30 °C. The produced rhamnolipids (RL), from diesel degrading bacteria, were characterized by Orcinol test and Mass spectrometry (MS). The MS confirmed that RLs structure compounds had a mixture of mono-rhamno-mono-lipidic, mono-rhamno-di-lipidic and di-rhamno-di-lipidic congeners. Burkholderia sp. produced a mixture of rhamnolipid homologues, as identified by mass spectrometry, while the composition of rhamnolipids depended upon the carbon substrates. The homologues rhamnolipid Rha-Rha-C10-C10, Rha-C10-C10 and Rha-Rha-C12-C12 were the predominant structures. Rha-C12-C14, Rha-C10-C12, Rha-Rha-C10-C12, and Rha-Rha-C12-C14 were detected as minor components. The efficient employment of Burkholderia sp., for the bioremediation of diesel contamination and production of RLs from it, could be recommended from this study.
       
  • Effect of different sterilization methods on physicochemical and
           microbiological properties of rice wine

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Tie-Yan Jin, Kandasamy Saravanakumar, Myeong-Hyeon Wang The present study investigated the effect of three different sterilization methods (high hydrostatic pressure sterilization, ultraviolet sterilization, and ultra-high temperature sterilization) on changes of physicochemical and microbiological properties of rice wine Makgeolli during the preservation at 15 °C for 20 weeks. The results indicated that pH, titratable acidity, color, contents of reducing sugar and alcohol were not significantly varied between different sterilization methods but microbial counts and sensory evaluation were exhibited the significant differences. The microbial counts of the sterilized Makgeolli were significantly lower than that in unsterilized one after 20 weeks of storage. Sensory profiles were markedly dependent on the sterilization methods. This work inferred, the high hydrostatic pressure treatment as the suitable method of sterilization for improving the shelf life of rice wine Makgeolli.
       
  • Biological and phytochemical studies of different leaves extracts of
           Pteropyrum scoparium

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Afaf Mohammed Weli, Samiya Al-Salmi, Horiya Al Hoqani, Mohammad Amzad Hossain Pteropyrum scoparium (P. scoparium, Sidaf) is a medicinally important plant available in most of the tropical countries including Sultanate of Oman and locally it is used to treat dyspepsia and blood purifying agent. The aim of the present study is to prepare leave extracts of different polarities and to evaluate their phytochemicals, total phenols content, antioxidant and antimicrobial activities. The leaves of the plant were extracted with absolute ethanol by maceration method at ambient temperature for one week. The extract was filtered and evaporated to dryness by using rotary evaporator. The residue was suspended in equal volume of ethanol: water and fractionation with hexane, chloroform, and butanol, respectively. The total phenols content, antioxidant and antimicrobial activities of four prepared extracts were evaluated by Folin-Ciocalteu reagent (FCR), 2,2-diphenyl-1-picrylhydrazyl (DPPH) and agar disc diffusion methods. The highest amount of phenols content was found in hydro alcoholic extract and the lowest content was in hexane to be in the order of hydro alcohol > butanol > chloroform > hexane extract. The main antioxidant activity was found in residue from butanol and the minimum activity was in that from chloroform, the order of antioxidant activity; butanol > hydro alcoholic > hexane > chloroform extract. The antibacterial activity of ethanol extract and its derived fractions of the plant against one Gram-positive Staphylococcus aureus (S. aureus) and one Gram-negative Escherichia coli (E. coli) bacteria strains were qualitatively assessed by the presence or absence of inhibition zones. All the extracts of the selected plant at most of the concentrations did not exhibit potent antibacterial activity. The phytochemical studies of the prepared extracts, showed that all the extract contains saponins, steroids, and terpenoids. In addition to that, the chloroform, butanol and hydro-alcohol extract contains tannins and glycoside. In conclusion, all the crude extracts showed significant antioxidant activity. It could be used as natural antioxidant instead of synthetic one.
       
  • Central composite design for optimization of preparation conditions and
           characterization of hydroxyapatite produced from catfish bones

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Abolaji Grace Farombi, Omotayo Sarafadeen Amuda, Abass Olanrewaju Alade, Aderonke Adetutu Okoya, Segun Akanmu Adebisi Hydroxyapatite (HAP) was prepared from catfish bones at optimized conditions by employing Central Composite Design (CCD) under Response Surface Methodology (RSM). The temperature of preparation ranges between 300 and 1000 °C and time was varied between 1 and 2 h. The software gave thirteen (13) runs experiment within the conditions. 10 g of treated catfish bones inside crucible was calcined in the furnace at the temperatures and times suggested by the software. The yield percentages were determined and a standard method of pore size estimation Methylene Blue Number Method was used to estimate the adsorption capacity of the calcined catfish bones (CFHAP). Hence, the optimized conditions for adsorption were deduced. Characterization of the catfish bones before and after calcinations was studied by using Scanning Electron Microscopy (SEM); Fourier Transform Infrared Spectroscopy (FTIR;) Energy Dispersive X –ray Spectroscopy (EDX) and Brunaver-Emmett-Teller (BET). The results confirmed that the product is hydroxyapatite.
       
  • Spectrophotometric and tandem mass spectroscopic analysis of Indian borage
           (Plectranthus amboinicus (Lour.) Spreng.) for its polyphenolics
           characterization

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): C.T. Sulaiman, M. Deepak, Indira Balachandran Plectranthus amboinicus (Lour.) Spreng. has been used for the treatment of many diseases in traditional Indian systems of medicine. In the present study, Polyphenolic profiling was carried out in leaves of P. amboinicus using spectrophotometric and mass spectroscopic analyses. The total Polyphenolics of different extracts such as ethanol, acetone and n-butanol were estimated spectrophotometrically and major phenolic compounds of ethanol extract was characterized by HPLC coupled tandem mass spectroscopic analysis.
       
  • Microwave-assisted extraction and characterization of fatty acid from eel
           fish (Monopterus albus)

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Haruna Kolawole Afolabi, Siti Kholijah Abdul Mudalip, Oluwaseun Ruth Alara Eel fish (Monopterus albus) is a functional food that has shown remarkable effects on a range of diseases, which include inflammatory diseases, type 2 diabetes and cancer. This study emphasized on the use of microwave-assisted extraction (MAE) technique in studying the effects of three MAE parameters (irradiation time, microwave temperature and microwave power) to obtain extract from eel fish using ethanol as the extracting solvent. The free fatty acid (FFA), acid value, fatty acid contents, and functional groups in the extract were also examined. More so, the maximum extraction yield of 16.13% w/w was obtained at a microwave power of 800 W, FFA and acid value of 1.35 and 2.69 mg KOH/g, respectively confirmed good quality of the obtained extract. In addition, the major fatty acid contents in the extract using gas chromatography-mass spectrometry (GC-MS) analysis were arachidonic acid, linolenic acid, myristic acid, oleic acid, palmitic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). Consequently, the Fourier transform infrared spectrometry (FTIR) analysis confirmed the presence of different functional groups in the extract. Therefore, this study divulged that MAE is an efficient and reliable technique for extracting high yields of fatty acids from M. albus fish with a notable potential for industrial applications.
       
  • Three-dimensional finite element analysis of a porcelain crowned tooth

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Bankole.I. Oladapo, S. Abolfazl Zahedi, F. Vahidnia, O.M. Ikumapayi, Muhammad U. Farooq The restoration of endodontically treated teeth is one of the main challenges in restorative dentistry since the weakened tooth structure is more prone to biomechanical failures due to significant tooth loss. The aim of this paper is to computational analysis of prepared crowned tooth in order to differentiate the possibility of using porcelain material for typical clinical condition and masticatory load by using the three-dimensional finite element method (3D FEM). In order to have an accurate geometry of tooth model, a coordinate measuring machine (CMM) is proposed to scan the tooth. The obtained scanned contours exported to ABAQUS FE package for computational stress analysis. The prosthodontics crown FEM has been created and put on simulated chewing stresses. The model is composed of four different materials, namely; prepared tooth, luting cement, substructure (IPS Empress Core), and Ingot (IPS Empress Layer). The generated FEM run and the stress distributions of the crowned tooth is thoroughly investigated. The developed model is extremely useful for indicating tooth biomechanics and has the tendency to deliver a better understanding to designers in the biomedical engineering field and dentistry.
       
  • l-cysteine+derivatives+as+multi-target-directed+ligands+for+the+treatment+of+neurodegenerative+diseases&rft.title=Beni-Suef+University+Journal+of+Basic+and+Applied+Sciences&rft.issn=2314-8535&rft.date=&rft.volume=">Design synthesis in silico in vitro and in vivo evaluation of novel
           l-cysteine derivatives as multi-target-directed ligands for the treatment
           of neurodegenerative diseases

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Vadivel Kannan, Manohar Babu Sitty, Muthusamy Periyannan There are four major molecular mechanisms involved in the neuronal cell death are excitotoxicity, neuroinflammation, apoptosis and oxidative stress. Our objective is to explore in silico, in vitro and in vivo evaluation of neuroprotective potential of novel l-Cysteine derivatives as multi-target-directed drugs to manage neurodegenerative diseases. Fifty molecules were designed and included in the in silico analysis to evaluate their druglikeness and binding affinities towards the selected target proteins using various pharmacokinetic and docking software. Based on in silico results and synthetic feasibility, nine compounds were selected for synthesis, spectral analysis, in vitro and in vivo neuroprotective evaluation on neuroblastoma cell line and aluminium induced neurotoxicity in rats. Selected compounds gained best docking score and obey Lipinski’s rule of five. In vitro results showed that the compound 1a and 1b significantly increased the percentage viability (81.03 ± 4.78 and 76.1 ± 1.99) of human neuroblastoma cells at concentration of 100 µg. Mean retention latencies and oxidative stress were significantly decreased (P 
       
  • An evidence of fungal derived 1-aminocyclopropane-1-carboxylate deaminase
           promoting the growth of mangroves

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Kandasamy Saravanakumar, Davoodbasha MubarakAli, Kandasamy Kathiresan, Myeong-Hyeon Wang The present study reports the enzyme 1-aminocyclopropane-1-carboxylate deaminase (ACCD) from Trichoderma strains TSK8 and SKS1 enhance the growth mangroves (Rhizophora) evidenced by primary enzyme quantification followed by greenhouse experiments. The results indicated that ACCD enzyme activity about 20% higher in strain SKS1 than that of strain TSK8. In the greenhouse study, we analyzed the effect of Trichoderma treatment on physiological and biochemical characteristics of mangrove seedlings. The results demonstrated that SKS1 significantly enhanced the growth of mangroves (Rhizophora apiculata and Rhizophora mucronata) as compared to control (untreated). The strain TSK8 and SKS1 increased the plant total biomass by 43.26% and 41.23% respectively in R. mucronata. Particularly, SKS1 showed the 70.8% biomass increase in R. apiculata. The growth was investigated with and without the addition of soluble phosphate were investigated. Thusly, the fungal strains SKS1 and TSK8 derived ACCD has potency on the mangroves growth enhancement. Thus present work provided the platform for the development of Trichoderma sp. based biofertilizer for a promising approach for the restoration of aquatic plants.
       
  • Design and assessment of pulsatile technology based chronomodulated
           delivery systems of nifedipine

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Sowjanya Battu, Prasanna Raju Yalavarthi, G.V. Subba Reddy, V. Uma Maheswara Rao, K. Jyothshna Devi, Harini Chowdary Vadlamudi Nifedipine has poor aqueous solubility which limits its oral absorption as unit formulation. This limitation was acted through multiparticulate pulsatile systems for the treatment of angina pectoris. Initially, solid dispersions of nifedipine (NF) using sodium starch glycolate (SSG) and guar gum (GG) in 1:1 and 1:2 ratios were processed by kneading technique. Solution layering technique was employed to coat the solid dispersions on non-pareil sugar spheres (∼450 µm) to obtain immediate (NMP 1 and 2) and controlled release pellets (NMP-3 and 4). Controlled release pellets were further coated with Eudragit L100 and RS100 to achieve pulsatile pellets (NMPP-1 to 5). Pellets were subjected to saturation solubility, FTIR, DSC, micromeritics, SEM, drug content, drug release, pharmacokinetic and stability studies. By means of solid dispersions, solubility of NF was increased by 130-folds due to encompassing ordered interparticle mixing of NF and carriers. Significant interactions between NF and carriers were not demonstrated in FTIR spectra as well as in DSC thermograms. Fluidization process again proved its supremacy in producing defined spherical shaped pellets with desired micromeritics. Solution layering process resulted with high drug content (81–94.2%) and maximum drug was released by end of 12 h with 6 h lag phase. Suitable pharmacokinetic parameters were moderated by immediate (NMP) and pulsatile pellets (NMPP) as Cmax of 820 ng/mL for NMP-2 and 360.8 ng/mL for NMPP-5 at 5 and 16 h respectively. Increased pharmacokinetics and bioavailability were the result of linear increase in solubility of NF with solid dispersions. The pulsatile formulations were physicochemically intact over a period of time. Thus, multiparticulate systems of NF had demonstrated their applicability in chronotherapy of circadian based ailments.
       
  • Optimization of the anticonvulsant activity of
           2-acetamido-N-benzyl-2-(5-methylfuran-2-yl) acetamide using QSAR modeling
           and molecular docking techniques

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Oluwaseye Adedirin, Adamu Uzairu, Gideon A. Shallangwa, Stephen E. Abechi Chemometric descriptors were used to analyze quantitatively the anticonvulsant activity of ninety propanamide derivatives. Molecular geometries of the data set were optimized with B3LYP/6-31G∗∗ quantum mechanical method and chemometric descriptors were calculated from the optimized structure. Linear QSAR models were developed using genetic function algorithm. Predictive capabilities of the models were evaluated using various internal and external validation techniques. The best three models proposed were octa-parametric equation with good statistical quality: R2 (0.898–0.918); Q2 (0.865–0.893); R2pred (0.746–0.772) and F (66.657–88.036). 2-acetamido-N-benzyl-2-(5-methylfuran-2-yl) acetamide a member of the data set was chosen as scaffold for in silico design. Using the information afforded by the models, several attempts were made to optimize the scaffold by introducing various modifications. Potential derivatives with higher predicted activity values than the template were identified and a detailed analysis on the models applicability domain defined the designed compounds, whose estimations can be accepted with confidence. Some of the designed compounds docked with γ-aminobutyrate aminotransferase (PBD: 1OHV) (target) showed better binding affinity for the target when compare with 4-aminohex-5-enoic acid (vigabatrin) (a known inhibitor of the target).
       
  • Antitumor activity of synthesized and characterized Cu(II), Ni(II) and
           Co(II) complexes of hydrazone-oxime ligands derived from 3-(hydroxyimino)
           butan-2-one

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Fathy A. El-Saied, Tarek A. Salem, Mohamad M.E. Shakdofa, Ahmed N. Al-Hakimi, Ahmed S. Radwan Mononuclear and binuclear metal complexes of hydrazone oxime resulted from the condensation of acetohydrazide and pyridyl hydrazide with 3-(hydroxyimino) butan-2-one were prepared. All compounds were characterized using elemental, spectral and thermal analyses, as well as magnetic moment and molar conductance measurements. The ligands acted as neutral/monobasic bidentate, monobasic tridentate and dibasic tetradentate ligands bonded to the metal ions via azomethine nitrogen or oxime oxygen atoms and enolic carbonyl oxygen or pyridine nitrogen atom. The spectral and magnetic studies of the complexes showed that exhibit either distorted octahedral, square planer or tetrahedral geometry. Newly complexes were tested for their anti-proliferative activity in vitro against three human cell lines; MCF-7, Hep-G2 and HL-60. The cytotoxic action of the complexes was determined and compared to that of the anticancer drug doxorubicin. Results of cytotoxicity activities indicated that the compound (6) has a wide range of cytotoxicity against the three cell lines in concentration ranges as that of doxorubicin. It shows more cytotoxic against MCF-7 (IC50 = 1.8 μM) and HL-60 (IC50 = 10.6 μM) cancer cell lines. Compounds (H2L1) and (11) exhibited higher cytotoxic activities rather than doxorubicin against MCF-7 and HL-60 cell line. Compounds (2) and (11) are 3.1 and 2.1 times more active than doxorubicin; respectively, against HL-60 cell line.
       
  • The genus Vitex: An overview of iridoids as chemotaxonomic marker

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): M. Oluwasesan Bello, Ahmed A. Zaki, Sinmisola Aloko, Pius S. Fasinu, E. Oluwatoyin Bello, Usman L. Ajao, Olubunmi S. Oguntoye In our continuing work on Vitex genus, the phytochemical investigation of leaves of Vitex grandifolia led to the isolation of two iridoids known in the literature as agnuside and bartsioside. The chemical structures were characterized by combined spectroscopic analysis. These compounds were isolated from this specie for the first time, this study give evidence to iridoids as chemotaxonomic marker and their constitutive presence has been reported in a number of genera in the family Lamiaceae. Iridoids have been isolated from nineteen species belonging to genus Vitex from Lamiaceae especially aucubin and agnuside. In addition to the utilization of morphological features of plants belonging to this genus, these compounds may be useful chemotaxonomic markers to aid taxonomic identification. This work evaluates and describes the distribution of iridoids in Vitex species to further establish this claim with structures of the iridoids found in this genus.
       
  • Fermentation of lignocellulose ingredients in vivo and in vitro via using
           fecal and caecal inoculums of monogastric animals (swine/turkeys)

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Ibrahim M.I. Youssef, Josef Kamphues Three experiments were performed to evaluate the digestibility and fermentation rates of two types of lignocellulose products that can be used in diets of pigs and turkeys. Experiment I: In vitro dry matter digestibility studies using Daisy system were conducted by using fecal or excreta fluid of swine/turkeys as a source of inoculums. The feedstuffs used as substrates were commercial swine or turkey diet, lignocellulose A and B. The dry matter digestibility was found to be about 75%, 28%, and
       
  • Earth-sheltered buildings in hot-arid climates: Design guidelines

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Heba Hassan, Daisuke Sumiyoshi One of the most effective techniques to meet the tradeoff between thermal comfort and low energy consumption in hot-arid climates is Earth sheltering.This paper reports the results of research series which aim to measure the suitability of applying the Earth sheltering technique at hot-arid climates, in Egypt as a case study.The research tested 164 experts’ responses about their attitude towards Earth-sheltered buildings and obtained their recommendations and preferences about the architectural and urban design guidelines.On the other hand, basement’s thermal performance was tested, through simulation and measurements to reach the calibration process.Moreover, measuring the balance between the thermal comfort, and energy savings through a parametric optimization analysis. The tested design variables were 25 window/wall ratio percentages, 23 orientation angles, and five cities location templates; Ismailia, Sharm-El-Shiekh, Al Minya, Marsa-Matrouh and Al Kharga.The research results present site-specific guidelines, through several topics; architectural design guidelines, site selection and urban planning guidelines, for architects and urban planners regarding the application of this technique for residential buildings.
       
  • A quantitative review and classification of empirical models for
           predicting global solar radiation in West Africa

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): Samuel Chukwujindu Nwokolo, Julie C. Ogbulezie The knowledge of the global solar radiation is of particular significance in reliable evaluation of the solar energy potential in a given locality. However, ground measurement of global solar radiation (GSR) is not available in most locations in West Africa. During the past 36 years in order to estimate GSR on the horizontal surface on both daily and monthly mean daily basis, several empirical models have been developed for numerous locations in West Africa. As a result, various input parameters have been utilized and numerous functional forms employed. In this study aimed at classifying and reviewing the empirical models employed for estimating GSR in West Africa, the empirical models so far utilized were classified into six main categories and presented based on the input parameters employed. The models were further reclassified into numerous main sub-classes (groups) and finally presented according to their developing year. On the whole, 356 empirical models and 68 functional forms were reported in literature for estimating GSR in West Africa. The authors equally compared the empirical and soft computing models for estimating GSR in West Africa and across the globe and observed that the soft computer models yielded better. Thus, this review would provide solar energy researchers in terms of identifying the input parameters and functional forms widely employed up till now as well as recognizing their importance for estimating GSR in several locations and need to adopt soft computing methods particularly promising as an alternative approach for estimate GSR with high precision in West Africa.
       
  • Numerical solution of nonlinear sine–Gordon equation by using the
           modified cubic B-spline differential quadrature method

    • Abstract: Publication date: December 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 4Author(s): H.S. Shukla, Mohammad Tamsir This paper deals with numerical solution of one dimensional nonlinear sine–Gordon. “Modified cubic B-spline differential quadrature method” is used to solve one dimensional nonlinear sine–Gordon. The method reduces the problem to a system of first order ordinary differential equations (ODEs). The resulting system of ODEs is solved by “an optimal five stage and fourth-order strong stability preserving Runge–Kutta (SSP-RK54) method”. Finally, the method is illustrated and compared with existing methods via numerical examples. It is found that the method not only is quite easy to implement, but also gives better results than the ones already existing in the literature.
       
  • Amelioration of DENA-induced oxidative stress in rat kidney and brain by
           the essential oil of Elettaria cardamomum

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Nihal M. Elguindy, Galila A. Yacout, Eman F. El Azab The goal of the present work was to study the protective role of the essential oil of Elettaria cardamomum (cardamom) against diethylnitrosamine (DENA)-induced oxidative stress in the kidney and brain of rats in comparison with geraniol, a pure compound as one of the main components of cardamom essential oil. Geraniol or cardamom essential oil was orally administered every day (100 and 200 mg/kg) for 1 week before DENA administration and continuously administered for 26 weeks. The levels of brain and kidney ornithine decarboxylase (ODC), brain acetylcholinesterase (AChE) and renal markers such as urea and creatinine were elevated after DENA administration. However, cardamom and geraniol administration decreased kidney and brain oxidative stress and lowered the activity of ODC in brain and kidney and the activity of AChE in brain. Cardamom or geraniol had significantly reduced the level of lipid peroxidation to almost half the value in DENA group and enhanced glutathione level by double its values in brain and kidney compared to glutathione levels in DENA treated-rats. In addition, geraniol or oil of cardamom improved the activities of the antioxidant markers; catalase, superoxide dismutase, glutathione peroxidase, glutathione reductase, and glutathione-S transferase in the brain and kidneys of DENA-treated rats. The results support the chemopreventive, antioxidant, neuroprotective and anticancer effects of the essential oil of cardamom, which are mediated through its inhibition of ODC and AChE activities and activation of antioxidant markers.
       
  • Morphological, histological and ultrastructural studies on the exocrine
           pancreas of goose

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Rasha Ragab Beheiry, Waheed Abdel-Azeem Abdel-Raheem, Ahmed Mostafa Balah, Hoda Foad Salem, Mayada Wahid Karkit The present work was aimed to study the morphological and histological features of goose pancreas and to investigate the ultrastructure of pancreatic acini. This study was conducted on the pancreas of ten healthy mature birds of goose. The pancreas was excised from the duodenum rapidly after slaughter of the birds. The specimens were fixed in 10% buffered neutral formalin then processed for light and electron microscopic study. The macroscopic observations revealed that goose pancreas was located in the right side of the abdomen between the ascending and descending loops of duodenum. It was formed from dorsal, splenic, ventral and third lobes. The histological observations revealed that the pancreas was formed of lobules of serous acini. The secretory acinus unit was appearing as a single spherical mass composed of many serous cells surrounding narrow lumen. The pyramidal acinar cells appeared bizonal structure; the basal basophilic cytoplasm and apical acidophilic cytoplasm. Centroacinar cells were slightly smaller cells that appeared brighter than the acinar cells and were located in the center of the lumen of the acinus. The duct system was well developed began with the centroacinar cells. Underneath electron microscope, the acinar cells have been two kinds, the electron dense acinar cells with electron dense cytoplasm and heterochromatic nuclei and the electron lucent acinar cells, which characterized by means of electron lucent cytoplasm, and their nuclei had considerable euchromatin, abundant endoplasmic reticulum, mitochondria and numerous zymogen granules, and considered active cells.
       
  • Water demand and waste management with respect to projected urban growth
           of Gurugram city in Haryana

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Anil Kumar Misra, Misbah Masoodi, Rohith P. Poyil, Naval Kishore Tewari Gurugram city (Haryana state) has witnessed unprecedented urban growth over the past two decades, owing to the escalation in population, immigration and unorganized expansion. Present study examines the spatial determinants and different features of urban growth till 2011 in the Gurugram city and based on the growth rates and probable demands, land use pattern changes for 2031, 2041 and 2051 have been projected. Using photogrammetric analysis, orthoimage of Gurugram city was prepared and through visual image interpretation land use map of Gurugram city was generated. The population escalation was calculated using population estimation method and land use pattern of Gurugram city was predicted for 2031, 2041 and 2051. Based on the land cover and land use pattern changes, strategies for managing the water resource and solid waste management have been proposed. Probable future changes in land cover patterns, urban growth and land use patterns are very useful for urban planning and managing the natural resources. The results of the study could help in understanding the urban growth processes and their patterns, and facilitate urban planners and policy makers to deal with rapid urban agglomeration processes and associated problems.
       
  • Design regulatory interaction network for anxiety disorders using R: A
           bioinformatics approach

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Nahida Habib, Bikash Kumar Paul, Md. Shadidul Islam, Kawsar Ahmed Bio-informatics research fields are progressively growing enriched with the incremental use of R tools. Anxiety Disorders can be defined as one of the most common mental disorders. They are tangible psychiatric disorders or a group of mental illnesses thought to be caused by either genetic vulnerability or environmental susceptibility factors. Several studies have revealed that anxiety is associated with an increased risk of Angina, Asthma, Diabetes, Heart Attack and High Blood Pressure. Thus, these five anxiety disorders must have some genetic association among them. Finding the genetic relationship among the above diseases will help to understand the gene linkage and connection association among them which leads to the way to common drug design. Here, after investigating the genetic association of Angina, Asthma, Diabetes, Heart Attack and High Blood Pressure a Regulatory Interaction Network is designed using R. The investigated diseases genes are collected, preprocessed, processed, mined and optimized using R. This research aimed to create a new dimension in the field of drug design.
       
  • Interplay of electrically conducting and non conducting walls on
           magnetohydrodynamic mixed convection flow in vertical permeable
           micro-channel in existence of induced magnetic field

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Basant K. Jha, Babatunde Aina In this article, flow formation of fully developed mixed convection flow of an incompressible, viscous and electrically conducting fluid in vertical permeable micro-channel in presence of induced magnetic field is analyzed. The effects of velocity slip and temperature jump are taken into account. The influence of induced magnetic field arising due to the motion of an electrically conducting fluid in the presence of transverse magnetic field is taken into consideration. The governing equations of the motion are a set of simultaneous ordinary differential equations and their exact solutions in dimensionless form have been obtained for the velocity field, the induced magnetic field and the temperature field. The expressions for the induced current density and skin friction have also been obtained. Numerical procedures are examined for various active parameters namely: suction/injection, rarefaction, fluid wall interaction, mixed convection, Hartmann number and the magnetic Prandtl number. Results revealed that, increase in Hartmann number and magnetic Prandtl number causes a pronounced reduction in skin friction.
       
  • Variation in seasonal prevalence and intensity of progenetic metacercariae
           of Clinostomum complanatum infection in Trichogaster fasciatus fish

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Shabnam Khan, Sakil Ahmed, M. Serajuddin, Mohammad Khalid Saifullah A total of 1242 out of 1484 Trichogaster fasciatus fish were found to be infected with metacercarial stage of Clinostomum complanatum where 14,258 parasites were recorded mainly from the peritoneal cavity, gills and viscera during five years of study period. The seasonal variations in prevalence, intensity and abundance of the parasitic infection were assessed. The maximum and minimum values of prevalence of metacercarial infection of C. complanatum in the fish were 92.40% and 70.40% during summer and winter respectively. Similarly, intensity and abundance of the parasite were maximum during summer as compared to winter and rainy seasons. The high prevalence of infection of the parasite during summer may be because of the time of emergence of cercariae in high temperature from snail vector and the environment.
       
  • BNP as a promising marker in prediction of malignant arrhythmias in pts
           with LV systolic dysfunction after an acute MI

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Ahmed Yassin, MohamedAbo Hamila, Ahmed Battah, Amal Rizk, SheriefMokhtar
       
  • Seasonal and spatial variation of aquatic macrophytes and phytoplankton
           community at El-Quanater El-Khayria River Nile, Egypt

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Mostafa M. El-Sheekh, Amany M. Haroon, Soad Sabae In this study, the phytoplankton biomass and species composition in El-Quanater El-Khayria (River Nile, Egypt) was analyzed at four sampling sites on a program of a seasonally sampling and supported by measurements of different water variables as well as biomass production of most common aquatic macrophytes. The major species of aquatic macrophytes were two submerged species (Ceratophyllum demersum and Ceratophyllum submersum), two emergent (Polygonum tomentosum and spontaneum), and one free floating aquatic macrophyte (Eichhornia crassipes). Considerable seasonal variations in water quality as well as macrophytes biomass were found in the studied areas, which result in a variation of phytoplankton flora. A total of 235 phytoplankton species belonging to 7 classes was recorded, with higher numbers in autumn and winter compared to spring and summer. The maximum number of phytoplankton (7238 × 104 L−1 cells) was recorded in winter, however, the lowest one (96 × 104 L−1 cells) recorded in spring. Chlorophyceae was the dominant group, forming 56.96% of the total phytoplankton biomass followed by Bacillariophyceae (34.82%), Cyanophyceae (7.99%), Cryptophyceae (0.10%), Dinophyceae (0.096%), Chrysophyceae (0.03%) and Euglenophyceae (0.02%). Chlorophyll a values ranged from 9.77 µg L−1 to 69.81 µg L−1, with a considerable seasonal and spatial variation. All phytoplankton classes as well as, chlorophyll a was negatively correlated with all aquatic macrophytes species except for C. submersum which correlated positively with chlorophyll a and Cyanophyceae. In addition, it was positively correlated with pH, conductivity and dissolved oxygen.
       
  • Synthesis, spectroscopy characterization and biological activities of some
           novel 1-(3-(N,N-dimethylamino)-1-(5-substituted thiophene-2-yl)
           propylidene semicarbazone Mannich base derivatives

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Chandravadivelu Gopi, Magharla Dasaratha Dhanaraju The main aim of this work was to synthesise a novel 1-(3-(N,N-dimethylamino)-1-(5-substituted thiophene-2-yl)propylidene semicarbazone Mannich base derivatives and examine the anti-diabetic and anti-inflammatory activities using alloxan-induced diabetic and carrageenan-induced paw oedema methods. These analogues were prepared by performing a condensation reaction between 1-(thiophen 2-yl) ethanone, formaldehyde, N,N-dimethyl amine hydrochloride and semicarbazide. The prepared analogues were characterised by FT-IR, 1H NMR, 13C NMR, mass spectroscopy and elemental analysis. The result reveals that most of the compounds were significantly reduced in the blood glucose level and inflammation of paw volume of experimental animals as compared to the standard drugs.
       
  • Efficient extraction of antioxidants from Vernonia cinerea leaves:
           Comparing response surface methodology and artificial neural network

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Oluwaseun Ruth Alara, Nour Hamid Abdurahman, Haruna Kolawole Afolabi, Olusegun Abayomi Olalere Despite response surface methodology (RSM) has been the most preferred statistical tool for optimizing extraction processes, artificial neural network (ANN) has been one of the most effective tools used for optimization and empirical modelling since the last two decades, most especially for non-linear equations. Thus, this study was carried out to compare the performance of RSM and ANN in optimizing the extraction yield and antioxidant capability of extract from Vernonia cinerea leaves using microwave-assisted extraction (MAE) techniques. The responses (extraction yield and antioxidant capabilities) were modelled and optimized as functions of four independent MAE parameters (irradiation time, microwave power level, ethanol concentration, and feed-to-solvent ratio) using RSM and ANN. The coefficient of determination (R2), root mean square error (RMSE) and absolute average deviation (AAD) were employed to compare the performance of both modelling tools. ANN model has a higher predictive potential compared to RSM model with higher correlation coefficients of 0.9912, 0.9928 and 0.9944 for extraction yield, DPPH and ABTS scavenging activities, respectively. Thus, ANN model could be a better alternative in data fitting for the MAE of antioxidants from Vernonia cinerea leaves.
       
  • Di-(2-ethylhexyl) Phthalate, a major bioactive metabolite with
           antimicrobial and cytotoxic activity isolated from River Nile derived
           fungus Aspergillus awamori

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Momen M. Lotfy, Hossam M. Hassan, Mona H. Hetta, Ahmed O. El-Gendy, Rabab Mohammed The main objective of this study is to investigate the still unexplored River Nile habitat since it was found little information on the chemistry and biology of the River Nile derived microorganisms. Therefor it was claimed to isolate a number of microorganisms, identify them and test their antimicrobial activities. On the other hand isolation of at least one bioactive metabolite from isolated fungus grown under static condition. A number of microorganisms has been isolated using three different media; TSA (Trypton Soya Agar), SDA (Sabroud Dextrose Agar) and ISP4 (International Streptomyces Project 4), their antimicrobial activities were studied using two agar diffusion methods; cup and modified agar disc methods. Chromatographic techniques were used for isolation of one compound which also tested for its antimicrobial and cytotoxic activity. Thirty-four versatile isolates were recovered, related to Gram positive bacteria, Gram negative bacteria, fungi and actinomycetes. The antimicrobial screening showed varying activities against tested strains in both methods. Isolation of Di-(2-ethylhexyl) Phthalate (DEHP) compound from fungus Aspergillus awamori had been succeeded, it is the first report for its isolation from the titled fungus, DEHP exhibited activity against Candida albicans fungus and the Gram positive bacteria Sarcina lutea, also DEHP showed cytotoxic activity against some carcinoma cell lines. It can be concluded that the River Nile could be a tremendous resource for production of bioactive metabolites.
       
  • Wheat germ and vitamin E decrease BAX/BCL-2 ratio in rat kidney treated
           with gentamicin

    • Abstract: Publication date: September 2018Source: Beni-Suef University Journal of Basic and Applied Sciences, Volume 7, Issue 3Author(s): Mohamed A.M. Kandeil, Kamel M.A. Hassanin, Eman T. Mohammed, Ghada M. Safwat, Doaa Sh. Mohamed The intracellular accumulation of gentamicin acts on mitochondria directly (by increasing oxidative stress) and indirectly (by increasing the proapoptotic BAX gene expression levels) and thus activates intrinsic pathway of apoptosis. This study intended to investigate the probable prophylactic effect of wheat germ as a nephro-protective agent in relation to vitamin E as a well-known natural antioxidant on a nephrotoxic model induced by gentamicin. Forty male Sprague Dawley rats were divided randomly into four groups; of 10 rats each: control group, gentamicin group (120 mg/kg/day i.p. for 15 days), vitamin E group (200 mg/kg orally for 45 days) and wheat germ group (20% of the diet for 45 days). Gentamicin injection was started on the 30th day for both groups (3) and (4). It was noticed that wheat germ significantly decreased BAX/BCL-2 ratio. The significant decrement in MDA level and the significant increment in total antioxidant capacity (TAC) level and catalase (CAT) activity of wheat germ treated rats reflecting its antioxidant activity. Additionally, the wheat germ succeeded in improvement of the kidney function of rats of this group which was manifested by amelioration of deteriorated serum creatinine, urea, sodium and potassium levels. In conclusion, the efficacy of wheat germ as anti-apoptotic and antioxidant was higher than that of vitamin E and it effectively protected against the direct and indirect toxic effects of gentamicin on kidney through regulation of BAX-BCL-2 gene expressions and further inhibition of mitochondrial cytochrome c translocation into cytosol.
       
  • Biochemical and Apoptotic Biomarkers of Experimentally Induced Traumatic
           Brain Injury: In Relation to Time since Death

    • Abstract: Publication date: Available online 31 January 2018Source: Beni-Suef University Journal of Basic and Applied SciencesAuthor(s): Amany Abdel-Rahman Mohamed, Khlood M. Elbohi, Nabela I. El Sharkawy, Mona A. Hassan The present study declares the relationship between the cause of death and postmortem biochemical marker alterations in CSF, serum and plasma. In addition, immunohistochemical and microarchitecture examination of brain tissue of White New Zealand rabbits at different PMI after traumatized death. Thirty adult male White New Zealand rabbits were divided into two main equal groups; the first was physically killed by cervical dislocation and the second through head trauma. Each group was subdivided into three PMIs (zero, 6, and 12hrs PM). CSF was used to detect the levels of K+, Na+, Ca++, albumin While, lactic acid, hypoxanthine, ammonia and uric acid concentrations were measured in plasma. Estimation of HMGB1, IL-1β and TNF-α were assessed in serum. In addition to immunohistochemical observations of Bcl-2 and P53 apoptotic proteins in brain tissue. The results revealed that some of the examined parameters as K+, Na+, albumin, ammonia, hypoxanthine and HMGB1 had the potential role in estimation of PMI at examined time periods in physical and traumatized death. Traumatic death induced severe cerebral hemorrhages and necrosis of cerebral parenchyma than physical death. Immunohistochemical results of P53 and Bcl-2 in brain tissue declared focal positive reactions of some neurons, astrocytes and microglia in different degrees with time since death. It was concluded that biochemical analysis of some body fluids, tissue pathological changes and apoptotic markers are applicable tools for assessing accurate PMI after traumatic brain injury and could have a crucial role in legal medicine
       
 
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