Subjects -> MEDICAL SCIENCES (Total: 8810 journals)
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INTERNAL MEDICINE (180 journals)                     

Showing 1 - 180 of 180 Journals sorted alphabetically
Abdomen     Open Access  
ACP Hospitalist     Full-text available via subscription   (Followers: 9)
ACP Internist     Full-text available via subscription   (Followers: 10)
ACP Journal Club     Full-text available via subscription   (Followers: 11)
Acta Clinica Belgica     Hybrid Journal   (Followers: 1)
Acute and Critical Care     Open Access   (Followers: 11)
Acute Medicine     Full-text available via subscription   (Followers: 9)
Advances in Hepatology     Open Access   (Followers: 4)
Advances in Integrative Medicine     Hybrid Journal   (Followers: 6)
African Journal of Primary Health Care & Family Medicine     Open Access   (Followers: 6)
African Journal of Thoracic and Critical Care Medicine     Open Access  
American Family Physician     Full-text available via subscription   (Followers: 38)
American Journal of Hypertension     Hybrid Journal   (Followers: 31)
Anales de Medicina Interna     Open Access   (Followers: 1)
Anatomy & Physiology : Current Research     Open Access   (Followers: 9)
Angiology     Hybrid Journal   (Followers: 5)
Annals of Colorectal Research     Open Access   (Followers: 1)
Annals of Internal Medicine     Full-text available via subscription   (Followers: 392)
AORN Journal     Hybrid Journal   (Followers: 27)
Apollo Medicine     Open Access  
Archives of Drug Information     Hybrid Journal   (Followers: 5)
Archivos de Medicina Interna     Open Access   (Followers: 1)
Asia Oceania Journal of Nuclear Medicine & Biology     Open Access   (Followers: 4)
Asian Pacific Journal of Tropical Disease     Full-text available via subscription   (Followers: 3)
Australasian Physical & Engineering Sciences in Medicine     Hybrid Journal   (Followers: 1)
BMI Journal : Bariátrica & Metabólica Iberoamericana     Open Access   (Followers: 1)
BMJ Open Diabetes Research & Care     Open Access   (Followers: 35)
BMJ Quality & Safety     Hybrid Journal   (Followers: 69)
Bone & Joint Journal     Hybrid Journal   (Followers: 138)
Brain Communications     Open Access   (Followers: 4)
Brain Science Advances     Open Access  
Canadian Journal of General Internal Medicine     Open Access   (Followers: 2)
Cardiovascular Medicine in General Practice     Full-text available via subscription   (Followers: 7)
Case Reports in Internal Medicine     Open Access   (Followers: 1)
Cell Death & Disease     Open Access   (Followers: 3)
Cellular and Molecular Gastroenterology and Hepatology     Open Access   (Followers: 3)
Cephalalgia     Hybrid Journal   (Followers: 8)
Cephalalgia Reports     Open Access   (Followers: 4)
Chronic Diseases and Injuries in Canada     Free   (Followers: 1)
Clinical Ethics     Hybrid Journal   (Followers: 13)
Clinical Liver Disease     Open Access   (Followers: 5)
Clinical Nutrition     Hybrid Journal   (Followers: 98)
Clinical Thyroidology     Full-text available via subscription   (Followers: 1)
CNE Pflegemanagement     Hybrid Journal  
Communication Law and Policy     Hybrid Journal   (Followers: 5)
Current Diabetes Reports     Hybrid Journal   (Followers: 30)
Current Hepatology Reports     Hybrid Journal  
Current Research: Integrative Medicine     Open Access  
CVIR Endovascular     Open Access   (Followers: 1)
Der Internist     Hybrid Journal   (Followers: 12)
Diabetes     Full-text available via subscription   (Followers: 603)
Diabetes Care     Full-text available via subscription   (Followers: 578)
Diabetes Internacional     Open Access  
Diabetes Spectrum     Full-text available via subscription   (Followers: 17)
Diagnosis     Hybrid Journal   (Followers: 1)
Egyptian Journal of Bronchology     Open Access  
Egyptian Journal of Internal Medicine     Open Access   (Followers: 1)
Egyptian Journal of Neurosurgery     Open Access  
Egyptian Liver Journal     Open Access   (Followers: 2)
Egyptian Spine Journal     Open Access  
EMC - Aparato Locomotor     Hybrid Journal  
Endovascular Neuroradiology / Ендоваскулярна нейрорентгенохірургія     Open Access   (Followers: 1)
eNeuro     Open Access   (Followers: 3)
Ergonomics     Hybrid Journal   (Followers: 24)
European Journal of Inflammation     Open Access   (Followers: 2)
European Journal of Internal Medicine     Full-text available via subscription   (Followers: 10)
European Journal of Translational Myology     Open Access  
European Radiology Experimental     Open Access   (Followers: 2)
Head and Neck Tumors     Open Access   (Followers: 1)
Health Sociology Review     Hybrid Journal   (Followers: 14)
HemaSphere     Open Access   (Followers: 2)
Hepatology Communications     Open Access  
Hepatoma Research     Open Access   (Followers: 3)
Human Physiology     Hybrid Journal   (Followers: 5)
ImmunoHorizons     Open Access  
Immunological Medicine     Open Access  
Infectious Diseases: Research and Treatment     Open Access   (Followers: 5)
Inflammation and Regeneration     Open Access   (Followers: 2)
Inflammatory Intestinal Diseases     Open Access  
Innere Medizin up2date     Hybrid Journal   (Followers: 1)
Internal and Emergency Medicine     Hybrid Journal   (Followers: 5)
Internal Medicine Journal     Hybrid Journal   (Followers: 9)
International Journal of Abdominal Wall and Hernia Surgery     Open Access   (Followers: 1)
International Journal of Anatomy and Research     Open Access   (Followers: 2)
International Journal of Angiology     Hybrid Journal  
International Journal of Artificial Organs     Hybrid Journal   (Followers: 3)
International Journal of Hyperthermia     Open Access  
International Journal of Internal Medicine     Open Access   (Followers: 3)
International Journal of Noncommunicable Diseases     Open Access  
International Journal of Psychiatry in Clinical Practice     Hybrid Journal   (Followers: 6)
Iranian Journal of Neurosurgery     Open Access   (Followers: 1)
Italian Journal of Anatomy and Embryology     Open Access   (Followers: 1)
JAC-Antimicrobial Resistance     Open Access   (Followers: 4)
JAMA Internal Medicine     Full-text available via subscription   (Followers: 364)
JCSM Clinical Reports     Open Access   (Followers: 3)
JHEP Reports     Open Access  
JIMD Reports     Open Access  
JMV - Journal de Médecine Vasculaire     Hybrid Journal   (Followers: 1)
Joint Commission Journal on Quality and Patient Safety     Hybrid Journal   (Followers: 41)
JOP. Journal of the Pancreas     Open Access   (Followers: 2)
Journal of Basic & Clinical Physiology & Pharmacology     Hybrid Journal   (Followers: 1)
Journal of Bone Oncology     Open Access   (Followers: 1)
Journal of Cancer & Allied Specialties     Open Access  
Journal of Clinical and Experimental Hepatology     Full-text available via subscription   (Followers: 3)
Journal of Clinical Movement Disorders     Open Access   (Followers: 3)
Journal of Community Hospital Internal Medicine Perspectives     Open Access  
Journal of Cutaneous Immunology and Allergy     Open Access  
Journal of Developmental Origins of Health and Disease     Hybrid Journal   (Followers: 2)
Journal of Endoluminal Endourology     Open Access  
Journal of Gastroenterology and Hepatology Research     Open Access   (Followers: 4)
Journal of General Internal Medicine     Hybrid Journal   (Followers: 23)
Journal of Hypertension     Hybrid Journal   (Followers: 14)
Journal of Infectious Diseases     Hybrid Journal   (Followers: 48)
Journal of Interdisciplinary Medicine     Open Access  
Journal of Internal Medicine     Hybrid Journal   (Followers: 11)
Journal of Liver : Disease & Transplantation     Hybrid Journal   (Followers: 7)
Journal of Medical Internet Research     Open Access   (Followers: 24)
Journal of Movement Disorders     Open Access   (Followers: 2)
Journal of Pain and Symptom Management     Hybrid Journal   (Followers: 46)
Journal of Pancreatic Cancer     Open Access  
Journal of Renal and Hepatic Disorders     Open Access  
Journal of Solid Tumors     Open Access   (Followers: 1)
Journal of Sports Medicine and Allied Health Sciences : Official Journal of the Ohio Athletic Trainers Association     Open Access   (Followers: 1)
Journal of the American Board of Family Medicine     Open Access   (Followers: 11)
Journal of the European Mosquito Control Association     Open Access  
Journal of Translational Internal Medicine     Open Access  
Jurnal Vektor Penyakit     Open Access  
La Revue de Medecine Interne     Full-text available via subscription   (Followers: 3)
Lege artis - Das Magazin zur ärztlichen Weiterbildung     Hybrid Journal   (Followers: 1)
Liver Cancer International     Open Access  
Liver Research     Open Access  
Molecular Diagnosis & Therapy     Hybrid Journal   (Followers: 3)
Molecular Therapy - Oncolytics     Open Access  
Multiple Sclerosis and Demyelinating Disorders     Open Access   (Followers: 7)
MYOPAIN. A journal of myofascial pain and fibromyalgia     Hybrid Journal   (Followers: 18)
Neuro-Oncology Advances     Open Access   (Followers: 1)
Neurobiology of Pain     Open Access   (Followers: 2)
Neurointervention     Open Access   (Followers: 6)
Neuromuscular Diseases     Open Access  
Nigerian Journal of Gastroenterology and Hepatology     Full-text available via subscription  
OA Alcohol     Open Access   (Followers: 5)
Oncological Coloproctology     Open Access  
Open Journal of Internal Medicine     Open Access  
Pleura and Peritoneum     Open Access  
Pneumo News     Full-text available via subscription  
Polish Archives of Internal Medicine     Full-text available via subscription   (Followers: 2)
Preventing Chronic Disease     Free   (Followers: 2)
Progress in Transplantation     Hybrid Journal   (Followers: 1)
Prostate International     Open Access   (Followers: 2)
Psychiatry and Clinical Psychopharmacology     Open Access   (Followers: 1)
Pulmonary Therapy     Open Access   (Followers: 2)
Quality of Life Research     Hybrid Journal   (Followers: 20)
Research and Practice in Thrombosis and Haemostasis     Open Access  
Revista Chilena de Fonoaudiología     Open Access   (Followers: 1)
Revista de la Sociedad Peruana de Medicina Interna     Open Access   (Followers: 4)
Revista del Instituto de Medicina Tropical     Open Access  
Revista Hispanoamericana de Hernia     Open Access   (Followers: 1)
Revista Médica Internacional sobre el Síndrome de Down     Full-text available via subscription   (Followers: 1)
Revista Virtual de la Sociedad Paraguaya de Medicina Interna     Open Access   (Followers: 1)
Romanian Journal of Diabetes Nutrition and Metabolic Diseases     Open Access   (Followers: 1)
Romanian Journal of Internal Medicine     Open Access  
Russian Journal of Child Neurology     Open Access   (Followers: 1)
Scandinavian Journal of Primary Health Care     Open Access   (Followers: 8)
Schlaf     Hybrid Journal  
Schmerzmedizin     Hybrid Journal  
Scientific Journal of the Foot & Ankle     Open Access   (Followers: 1)
SciMedicine Journal     Open Access   (Followers: 3)
SEMERGEN - Medicina de Familia     Full-text available via subscription   (Followers: 1)
The Journal of Critical Care Medicine     Open Access   (Followers: 9)
Therapeutic Advances in Chronic Disease     Open Access   (Followers: 8)
Therapeutic Advances in Musculoskeletal Disease     Hybrid Journal   (Followers: 6)
Thieme Case Report     Hybrid Journal   (Followers: 1)
Tijdschrift voor Urologie     Hybrid Journal  
Tissue Barriers     Hybrid Journal   (Followers: 1)
Transactions of the Royal Society of Tropical Medicine and Hygiene     Hybrid Journal   (Followers: 3)
Transgender Health     Open Access   (Followers: 3)
Trends in Anaesthesia and Critical Care     Full-text available via subscription   (Followers: 23)
US Cardiology Review     Open Access  
Vascular and Endovascular Review     Open Access   (Followers: 1)
Ожирение и метаболизм     Open Access  

           

Similar Journals
Journal Cover
Progress in Transplantation
Journal Prestige (SJR): 0.47
Citation Impact (citeScore): 1
Number of Followers: 1  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 1526-9248 - ISSN (Online) 2164-6708
Published by Sage Publications Homepage  [1151 journals]
  • Life Expectancy After Liver Transplantation for Hepatocellular Carcinoma
           With Cirrhosis
    • Authors: Ji Hun Kwak, Robert Shavelle, Jordan Brooks
      Pages: 62 - 71
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 62-71, March 2021.
      Background:Hepatocelluar carcinoma, the most common primary liver cancer, has a historically dire prognosis. For hepatic cancer patients with cirrhosis who underwent liver transplantation, we sought to calculate life expectancies both at time of transplant and several years later, stratified by some key variables, and to determine if survival has improved in recent years.Methods:Data on 13,797 hepatic cancer patients with cirrhosis who underwent liver transplantation in the MELD era (2002-2018) from the US Organ Procurement and Transplantation Network database were analyzed using the Cox proportional hazards regression model and life table methods.Results:The major factors related to survival were age, donor age, transplant year, diabetes, functional status, and the presence of severe hepatic encephalopathy. Survival was significantly worse with increasing age and decreasing functional status level. There was no significant difference in survival between males and females. Survival improved over the study period, at 5% per calendar year during the first 5 years post transplant, and 1% per year thereafter.Conclusions:Life expectancies were markedly reduced from normal, even among 5-year survivors with the most favorable characteristics. Survival improved modestly over the years 2002-2018.
      Citation: Progress in Transplantation
      PubDate: 2021-03-09T10:23:51Z
      DOI: 10.1177/1526924820978603
      Issue No: Vol. 31, No. 1 (2021)
       
  • Assessing How a Transplant Hospitality House for Patients and Families Can
           Promote Wellbeing
    • Authors: Talia C. Giordano, Jan L. Weinstock, Jennifer W. Campbell
      Abstract: Progress in Transplantation, Ahead of Print.
      Patients and caregivers face increasingly complex and unique challenges when they travel to distant hospitals for transplant care. They can find themselves in a strange city managing hospital stays and outpatient appointments, requiring lodging, food, transportation, financial assistance, and emotional support. Those unable to overcome these logistical challenges may lose access to lifesaving treatment. Transplant specific hospitality houses have emerged to support patients who travel long distances from home to seek care, though little is known about the impact of such programs. Can a transplant hospitality house impact opportunities for family-centered care, perceptions of physiological and physical security, and perceptions of belonging and esteem' Can their contributions also be linked to perceived positive health outcomes and what aspects of a transplant hospitality house are most significant for a patient’s and caregiver’s health journey' One transplant hospitality house investigated these questions with 71 participating in focus groups or key stakeholder interviews: transplant patients and caregivers, transplant hospital social workers, volunteers, financial contributors, board members, and staff. The findings suggest that while patients and caregivers were dependent and deeply grateful for the lodging and amenities that met their basic needs, it was the contact and support from other patients and caregivers at the transplant hospitality house that had the most profound positive impact on patient and family attitudes, outlooks, and perceived well-being.
      Citation: Progress in Transplantation
      PubDate: 2021-04-01T09:04:27Z
      DOI: 10.1177/15269248211003561
       
  • Vitamin D Levels and the Risk of Posttransplant Diabetes Mellitus After
           Kidney Transplantation
    • Authors: Kevin Quach, Monica Abdelmasih, Pei Xuan Chen, Yanhong Li, Olusegun Famure, Michelle Nash, Ramesh Prasad, Bruce A. Perkins, Paul M. Yip, S. Joseph Kim
      Abstract: Progress in Transplantation, Ahead of Print.
      Introduction:Given the burden of posttransplant diabetes mellitus and the high prevalence of low vitamin D levels in kidney transplant recipients, it is reasonable to consider vitamin D as a novel and potentially modifiable risk factor in this patient population.Research question:To determine the association between 25- hydroxyvitamin D (25(OH)D) level and posttransplant diabetes among kidney transplant recipients. Design: In a multi-center cohort study of 442 patients who received a kidney transplant between January 1, 2005 and December 31, 2010, serum samples within one-year before transplant were analyzed for 25(OH)D levels. The association between 25(OH)D and posttransplant diabetes were examined in Cox proportional hazard models.Results:The median 25(OH)D level was 66 nmol/L. The cumulative probability of diabetes at 12-months by quartiles of 25(OH)D (< 42, 42 to 64.9, 65 to 94.9, and > 95 nmol/L) were 23.4%, 26.9%, 21.4%, and 15.6%, respectively. Compared to the highest 25(OH)D quartile, hazard ratios (95% CI) for the risk were 1.85 (1.03, 3.32), 2.01 (1.12, 3.60), 1.77 (0.96, 3.25) across the first to third quartiles, respectively. The associations were accentuated in a model restricted to patients on tacrolimus. When modeled as a continuous variable, 25(OH)D levels were significantly associated with a higher risk of diabetes (hazard ratio 1.06, 95% CI: 1.01, 1.13 per 10 nmol/L decrease).Discussion:Serum 25(OH)D was an independent predictor of posttransplant diabetes in kidney transplant recipients. These results may inform the design of trials using vitamin D to reduce the risk in kidney transplant recipients.
      Citation: Progress in Transplantation
      PubDate: 2021-04-01T09:00:01Z
      DOI: 10.1177/15269248211002796
       
  • What Are the Burden, Causes, and Costs of Early Hospital Readmissions
           After Kidney Transplantation'
    • Authors: Olusegun Famure, Esther D. Kim, Magdalene Au, Roman E. Zyla, Johnny W. Huang, Pei Xuan Chen, Yanhong Li, S. Joseph Kim
      Abstract: Progress in Transplantation, Ahead of Print.
      Introduction:Kidney transplant recipients are at risk for complications resulting in early hospital readmission. This study sought to determine the incidences, risk factors, causes, and financial costs of early readmissions.Design:This single-centre cohort study included 1461 kidney recipients from 1 Jul 2004 to 31 Dec 2012, with at least 1-year follow-up. Early readmission was defined as hospitalization within 30 or 90-days postdischarge from transplant admission. Associations between various parameters and 30 and 90-days posttransplant were determined using multivariable Cox proportional hazards models. The hospital-associated costs of were assessed.Results:The rates of early readmission were 19.4% at 30 days and 26.8% at 90 days posttransplant. Mean cost per 30-day readmission was 11 606 CAD. Infectious complications were the most common reasons and resulted in the greatest cost burden. Factors associated with 30 and 90-days in multivariable models were recipient history of chronic lung disease (hazard ratio or HR 1.78 [95%CI: 1.14, 2.76] and HR 1.68 [1.14, 2.48], respectively), median time on dialysis (HR 1.07 [95% CI: 1.01, 1.13]and HR 1.06 [95% CI: 1.01, 1.11], respectively), being transplanted preemptively (HR 1.75 [95% CI: 1.07, 2.88] and HR 1.66 [95% CI: 1.07, 2.57], respectively), and having a transplant hospitalization lasting of and more than 11 days (HR 1.52 [95% CI: 1.01, 2.27] and HR 1.65 [95% CI: 1.16, 2.34], respectively).Discussion:Early hospital readmission after transplantation was common and costly. Strategies to reduce the burden of early hospital readmissions are needed for all patients.
      Citation: Progress in Transplantation
      PubDate: 2021-03-24T09:26:11Z
      DOI: 10.1177/15269248211003563
       
  • A Narrative Review of Qualitative Studies Describing Access to Kidney
           Transplantation
    • Authors: Molly Ranahan, Beth Dolph, Jon VonVisger, Renee Cadzow, Thomas Feeley, Liise K. Kayler
      Abstract: Progress in Transplantation, Ahead of Print.
      Background:This review used the Information-Motivation-Behavioral Skills (IMB) model of health behavior change to conceptualize the determinants of kidney transplant access behavior for adult patients with end-stage renal disease (ESRD).Methods:A narrative review of qualitative studies of patient access to kidney transplantation was undertaken. Only articles in English were accessed. The existing literature was critically analyzed using theoretical constructs of the IMB model and thematic synthesis was performed.Results:Results suggest patients having more information (greater transplant knowledge), more personal motivation (higher transplant outcomes expectations), more social motivation (more social and provider support), and more selfefficacy (confidence in navigating the transplant continuum) may be more likely to perform transplant access behaviors.Conclusion:Our findings provide a framework for considering patients’ levels of knowledge, motivation, and self-efficacy in future educational and behavioral interventions for ESRD patients.
      Citation: Progress in Transplantation
      PubDate: 2021-03-24T09:16:21Z
      DOI: 10.1177/15269248211002804
       
  • Program Evaluation or Original Research'
    • Authors: Rebecca P. Winsett
      Abstract: Progress in Transplantation, Ahead of Print.

      Citation: Progress in Transplantation
      PubDate: 2021-03-23T09:15:15Z
      DOI: 10.1177/15269248211003756
       
  • Identifying Needs and Barriers to Engage Family Members in Transplant
           Candidate Care
    • Authors: Warren T. McKinney, Marilyn J. Bruin, Sophie Kurschner, Melissa R. Partin, Allyson Hart
      Abstract: Progress in Transplantation, Ahead of Print.
      Introduction:Friends and family members provide critical support to patients on the waitlist for deceased donor kidney transplantation. However, little is known about how best to support and engage them effectively to improve patient outcomes.Methods:We conducted 5 focus groups with the family members of patients on the waitlist for a deceased donor kidney (n=23) to identify individual- and group-level targets for an intervention. Discussions encouraged participants to reflect on their support roles, experiences at the transplant evaluation, interactions with providers, knowledge of transplant options and expected outcomes. Transcripts of study sessions were coded using an iterative and inductive process.Results:The thematic analysis produced two main themes related to experiences providing care to patients on the waitlist for kidney transplantation. First, participants revealed that supporting a patient on the waitlist created challenges that reverberate through their entire social structure. Family members discussed frustrations with adapting to their patient’s kidney health needs, feelings of isolation, and barriers to identifying and building effective support networks. Second, participants described multiple challenges that prevented their patient-family unit from making informed decisions about transplant care. These challenges included communication with their patient, patients resisting help, difficulty understanding the information, and feeling helpless.Conclusion:Family members providing care to patients with end-stage kidney disease require targeted support to overcome the unique challenges associated with their role in helping to meet their patient’s clinical needs. Interventions to engage friends and family members in the care of kidney transplant candidates need to effectively address these challenges.
      Citation: Progress in Transplantation
      PubDate: 2021-03-23T09:12:15Z
      DOI: 10.1177/15269248211002794
       
  • Cytomegalovirus Disease, Short-Term Cardiovascular Events and Graft
           Survival in a Cohort of Kidney Transplant Recipients With High CMV IgG
           Seroprevalence
    • Authors: James S. Díaz, Fabián A. Jaimes
      Abstract: Progress in Transplantation, Ahead of Print.
      Introduction:Both cytomegalovirus (CMV) infection and CMV disease have been linked with several long-term indirect effects in kidney transplant recipients. Research questions: We conducted a retrospective study to assess the association between cytomegalovirus disease and risks of death, shortterm cardiovascular events and graft loss in a cohort of renal transplant recipients.Design:The associations between CMV disease and death and cardiovascular events were determined using Cox regression models, while the association between viral disease and graft loss risk was analyzed through a competing risks regression according to the Fine and Gray method. Death with a functioning graft was considered as a competing risk event.Results:A total of 865 consecutive renal transplant recipients were included. The prevalence of seropositive donor/seronegative recipient (D+/R-) group was 89.9% with the remaining patients classified as seropositive recipient (R+). After median follow-up time of 24.4 months, CMV disease was not a risk factor for all-causes mortality (HR = 1.75; 95% CI 0.94-3.25), early cardiovascular events (HR = 0.54; 95% CI 0.16-1.82) or graft loss (subhazard ratio [the HR adjusted for competing risk of death with functioning graft] = 0.99; 95% CI 0.53-1.84).Conclusions:In this cohort with high prevalence of CMV IgG antibodies, we found no association between cytomegalovirus disease and risk of death or graft loss. The relationship between CMV and cardiovascular disease remains to be unraveled and probably corresponds to a multifactorial phenomenon involving individual risk factors and the immune response to infection rather than the virus effect itself.
      Citation: Progress in Transplantation
      PubDate: 2021-03-19T09:23:40Z
      DOI: 10.1177/15269248211002792
       
  • Ideal Body Weight-Based Dosing of Rabbit Antithymocyte Globulin for Cost
           Minimization in Kidney Transplantation
    • Authors: Rachel J. Bubik, Kristen T. Peterson, Laura J. Myhre, Stacy A. Bernard, Patrick Dean, Heather P. May
      Abstract: Progress in Transplantation, Ahead of Print.
      Introduction:Contemporary dosing strategies for rabbit anti-thymocyte globulin (rATG) in kidney transplantation aim to reduce cumulative exposure, minimizing long-term adverse events. The use of ideal body weight-based dosing has been trialed, however concern for increased rejection post-transplant exists due to lower doses of rATG. Research Questions: The primary aim of this study was to compare rejection rates between rATG dosing protocols using actual body weight and ideal body weight and secondarily to evaluate cost savings following protocol implementation.Design:This was a retrospective study surrounding implementation of an ideal body weight-based dosing protocol for rATG. We compared 75 kidney transplant recipients in whom rATG was dosed based on actual body weight (pre-protocol group) to 64 in whom dosing was based on ideal body weight (post-protocol group), following a nine-month washout.Results:The mean cumulative rATG dose in the pre-protocol group was 6.3 mg/kg of actual body weight. When ideal body weight was used in the post-protocol group, the mean dose was 4.5 mg/kg of actual body weight. The rejection rate was 18.7% pre-protocol and 23.4% postprotocol, which did not represent a statistically significant difference (p = 0.491). The actual annual cost savings after protocol implementation exceeded $162,000, approximately $2,500 per patient.Conclusion:Results suggest ideal body weight-based dosing of rATG may reduce exposure and cost, without significantly impacting the risk of rejection in kidney transplant recipients. More studies are needed to confirm these findings.
      Citation: Progress in Transplantation
      PubDate: 2021-03-18T09:12:37Z
      DOI: 10.1177/15269248211003257
       
  • Donor Gamma-Glutamyl Transferase Is Associated With Liver Allograft
           Discard and Failure
    • Authors: Theodore Zhang, Brian Hickner, Ronald Cotton, Nhu Thao Nguyen Galvan, John M Vierling, Christine O’Mahony, John A Goss, Abbas Rana
      Abstract: Progress in Transplantation, Ahead of Print.
      Introduction:The disparity between the number of individuals on the wait list and available liver allografts creates the need for a system that maximizes donor liver utilization and predicts graft failure.Research Question:This study aimed to determine the relationship between donor Gamma-Glutamyl Transferase (GGT), liver discard, and graft failure.Design:Through multivariate analysis from 53 966 deceased liver donors, we adjusted for donor clinical and demographic characteristics and compared donor GGT with allograft discard. We compared donor GGT ranges with graft failure and analyzed data from 47 269 liver recipients.Results:After adjusting for other factors, donor GGT was significantly associated with liver discard, with GGT over 200 U/L being most significant (OR 2.74, CI 2.51-2.99). Donor GGT under 20 U/L was also found to be a protective factor for post-transplant graft failure (HR 0.91, CI 0.83 – 1.00).Conclusion:Going forward, GGT should be included among other characteristics associated with allograft discard considered during the procurement process.
      Citation: Progress in Transplantation
      PubDate: 2021-03-17T09:24:16Z
      DOI: 10.1177/15269248211002800
       
  • Cavoportal Transposition for the Management of Extensive Portal System
           Thrombosis During Liver Transplantation
    • Authors: Antonio Cubisino, Francis Navarro, Fabrizio Panaro
      Abstract: Progress in Transplantation, Ahead of Print.

      Citation: Progress in Transplantation
      PubDate: 2021-03-16T05:17:30Z
      DOI: 10.1177/15269248211002812
       
  • The Impact and Implications of The COVID-19 Pandemic on Organ Procurement
           Outside of an Epicenter
    • Authors: Janice Jene Hudgins, Allison Jo Boyer, Kristen Danielle Orr, Clint Allen Hostetler, Jeffrey Paul Orlowski, Ronald A. Squires
      Abstract: Progress in Transplantation, Ahead of Print.
      The COVID-19 pandemic has been well-documented to have a variable impact on individual communities and health care systems. We describe the experience of a single organ procurement organization (OPO), located in an area without a large cluster of cases during the initial phase of the COVID-19 pandemic. A review of community health data describing the impact of COVID-19 nationally and in Oklahoma was conducted. Additionally, a retrospective review of available OPO data from March 2019-May 2020 was performed. While the amount of donor referrals received and organs recovered by the OPO remained stable in the initial months of the pandemic, the observed organs transplanted vs. expected organs transplanted (O:E) decreased to the lowest number in the 15-month period and organs transplanted decreased as well. Fewer organs from Oklahoma donors were accepted for transplant despite staff spending more time allocating organs.
      Citation: Progress in Transplantation
      PubDate: 2021-03-16T05:16:50Z
      DOI: 10.1177/15269248211002808
       
  • Life Expectancy after Liver Transplantation for Non-Cirrhotic
           Hepatocellular Carcinoma
    • Authors: Robert M. Shavelle, Ji Hun Kwak, Rachel Saur, Jordan C. Brooks, Philip Rosenthal
      Abstract: Progress in Transplantation, Ahead of Print.
      Background:Hepatocelluar carcinoma typically occurs with underlying cirrhosis. However roughly 20% of cases arise in a non-cirrhotic liver. There is limited literature that addresses the long-term survival of the narrow subgroup who received transplantation. For such patients we sought to calculate life expectancies both at time of transplant and several years later, stratified by key risk factors, and to determine if survival has improved in recent years. Such information can be helpful in making treatment decisions.Methods:Data on 4,373 non-cirrhotic HCC patients who underwent liver transplantation in the MELD era (2002-2018) from the United States OPTN database were analyzed using the Cox proportional hazards regression model and life table methods.Results:Demographic and past medical history factors related to survival were patient age, donor age over 20, and the presence of ascites or severe hepatic encephalopathy. Survival did not vary by race or sex. HCC-specific factors significantly related to survival were the total number of tumors, extrahepatic spread, lymph node involvement, satellite lesions, micro- or macrovascular invasion, tumor differentiation (grade), and pre-transplant treatment. Survival improved over the study period, at 4% per calendar year during the first 5 years post transplant and 1% per year thereafter.Conclusions:Life expectancy in non-cirrhotic HCC transplant patients is much reduced from normal, and varies according to age and tumor-related factors. Survival improved modestly over the study period.
      Citation: Progress in Transplantation
      PubDate: 2021-03-16T05:15:50Z
      DOI: 10.1177/15269248211002793
       
  • The Need for Consensus About Liver Transplantation For Patients With
           Neuropsychiatric Wilson’s Disease
    • Authors: Alberto Ferrarese, Patrizia Burra
      Abstract: Progress in Transplantation, Ahead of Print.
      Liver transplantation is considered an effective therapeutic option for Wilson’s disease (WD) patients with hepatic phenotype, since it removes the inherited defects of copper metabolism, and is associated with excellent graft and patient outcomes. The role of liver transplantation in WD patients with mixed hepatic and neuropsychiatric phenotype has remained controversial over time, mainly because of high post-operative complications, reduced survival and a variable, unpredictable rate of neurological improvement. This article critically discusses the recently published data in this field, focussing in more detail on isolated neuropsychiatric phenotype as a potential indication for liver transplantation in WD patients.
      Citation: Progress in Transplantation
      PubDate: 2021-03-12T05:10:31Z
      DOI: 10.1177/15269248211002806
       
  • Progress in Transplantation Moves to Online-Only Publication
    • Authors: Rebecca P. Winsett
      Pages: 3 - 3
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 3-3, March 2021.

      Citation: Progress in Transplantation
      PubDate: 2020-12-08T09:38:45Z
      DOI: 10.1177/1526924820979060
      Issue No: Vol. 31, No. 1 (2020)
       
  • The Utility of a Pre-Transplant Psychosocial Evaluation in Predicting
           Post-Liver Transplant Outcomes
    • Authors: Jacqueline H. Becker, Eyal Shemesh, Akhil Shenoy, Ailie Posillico, Christopher S. Knight, Se-Kang Kim, Sander S. Florman, Thomas Schiano, Rachel A. Annunziato
      Pages: 4 - 12
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 4-12, March 2021.
      Background:There is insufficient evidence about the ability of pretransplant psychosocial evaluations to predict posttransplant outcomes. While standardized assessments were developed to increase predictive validity, it is unclear whether the risk scores they yield predict outcomes. We investigated if the Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT), a scaling approach to those assessments, would have been a superior predictor than the standard psychosocial evaluation.Methods:In this retrospective study, medical records of 182 adult liver transplant recipients who were at least 1 year posttransplant and prescribed tacrolimus for immunosuppression were analyzed. Regression analyses predicted outcomes of interest, including immunosuppressant nonadherence and biopsy-proven rejection, obtained 1-year posttransplant to time of data collection. Nonadherence was determined using the medication level variability index (MLVI).Results:Approximately 49% of patients had MLVI > 2.5, suggestive of nonadherence, and 15% experienced rejection. SIPAT total score did not predict adherence either using the continuous (P = .70), or dichotimized score, above or below > 2.5 (P = .14), or rejection (P = 0.87). Using a SIPAT threshold (total score > 69) did not predict adherence (p = .16) nor was a superior predictor of the continuous adherence score (P = .45), MLVI > 2.5 (P = .42), or rejection (P = 0.49), than the standard evaluation.Conclusion:Our findings suggest that the SIPAT is unable to predict 2 of the most important outcomes in this population, immunosuppressant adherence and rejection. Research efforts should attempt to evaluate the best manner to use psychosocial evaluations.
      Citation: Progress in Transplantation
      PubDate: 2020-12-04T08:53:03Z
      DOI: 10.1177/1526924820978605
      Issue No: Vol. 31, No. 1 (2020)
       
  • Analysis of Linguistically and Culturally Tailored Initiatives in Websites
           of Kidney Transplant Programs in the United States Between 2013-2018
    • Authors: Juan Carlos Caicedo, Samuel Carbunaru, Joseph Tyler Brooks, Christopher Chiodo Ortiz, Alejandro Chiodo Ortiz, Xiomara Benavides, Laura Niño, Jorge Ortiz, Jayme E. Locke
      Pages: 13 - 18
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 13-18, March 2021.
      Introduction:Minority patients constitute the majority of the kidney transplant waiting list, yet they suffer greater difficulties in listing and longer wait times to transplantation. There is a lack of information regarding targeted efforts by transplant centers to improve transplant care for minority populations.Research Question:Our aim was to analyze all kidney transplant websites in the United States to identify changes over a 5-year period in the number of multilingual websites, reported culturally targeted initiatives, and center and provider diversity.Design:Surveys were developed to analyze center websites of all transplant programs in the United States. Those with incomplete information about their nephrology or surgical teams were excluded, resulting in 174 (73%) sites in 2013 and 185 (76%) in 2018. Results: Few websites were available in a language other than English, 6.3% in 2013 and 9.7% in 2018 (P = 0.24). Only 3 websites (1.3%) in 2013 and 7 (3.7%) in 2018 reported any evidence of a culturally targeted initiative (P = 0.23). In 2018, 35% of centers employed a Hispanic transplant physician, 77% had a transplant physician who spoke a language other than English, and 39% had a transplant physician who spoke Spanish.Discussion:Although minority patients are expected to grow in the United States, decreased access to transplantation continues to vex the transplant community. Very little progress has been made in the development of multilingual websites and culturally targeted initiatives.
      Citation: Progress in Transplantation
      PubDate: 2020-12-23T09:37:13Z
      DOI: 10.1177/1526924820978593
      Issue No: Vol. 31, No. 1 (2020)
       
  • How Can We Help Alleviate the Financial Concerns of Non-Directed
           (Altruistic) Living Kidney Donors'
    • Authors: Ariella Maghen, Georgina Mendoza, Grecia B. Vargas, Sarah E. Connor, Sima Nassiri, Lorna Kwan, Erika L. Wood, Jonathan Lalezari, Sarah Friedman, Amy D. Waterman, Sheba George, Sally L. Maliski, Jeffrey L. Veale
      Pages: 19 - 26
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 19-26, March 2021.
      Introduction:The recent increase in non-directed donors (NDDs) in the United States (U.S.) may help reduce the overwhelming number of patients on the waitlist. However, non-directed donation may be limiting its full potential. Out-of-pocket donation costs upward of $8,000 may be a barrier to potential donors with altruistic tendencies, but inadequate financial support. This study aimed to describe the financial concerns of 31 U.S. NDDs.Methods:We conducted qualitative interviews and administered quantitative demographic surveys between April 2013 and April 2015. Interview transcripts were analyzed using grounded theory techniques to describe and expand on themes relevant to the NDD experience.Findings:We identified 4 sub-themes related to the theme of financial concerns: (1) direct costs related to transportation, lodging, and parking, (2) indirect costs of lost wages encountered from taking time off work to recover from surgery, (3) sources of financial support, and (4) suggestions for alleviating donor financial burden. Two thirds of participants (20) expressed concerns about direct and indirect donation costs. 11 NDDs reported the negative impact of direct costs,15 NDDs had concerns about indirect costs; only 7 donors received supplemental financial support from state mandates and transplant programs.Discussion:Understanding the financial concerns of NDDs may guide improvements in the NDD donation experience that could support individuals who are interested in donating but lack the financial stability to donate. Removing financial disincentives may help increase nondirected donation rates, increase the living donor pool, and the number of kidneys available for transplantation.
      Citation: Progress in Transplantation
      PubDate: 2020-12-09T09:49:46Z
      DOI: 10.1177/1526924820978589
      Issue No: Vol. 31, No. 1 (2020)
       
  • The Educational Value and Emotional Impact on Medical Students After
           Participating in Transplant Organ Retrieval
    • Authors: Alistair J. M. Reed, Rhiannon Baldwin-Smith, James Arwyn-Jones, Simon Knight, Isabel Quiroga
      Pages: 27 - 31
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 27-31, March 2021.
      Introduction:Medical students and healthcare professionals lack knowledge and confidence in organ transplantation which stems in part from a lack of exposure to transplant surgery at medical school. To address this, we developed a program that allowed students to attend organ retrievals and assessed its efficacy as an educational intervention.Methods:Students were invited to attend organ retrievals through a voluntary program. Students then completed an anonymous, self-administered questionnaire (n = 40) designed to capture the perceived educational value and emotive impact of attending an organ retrieval, and its effect on career aspirations. Quantitative and qualitative data were analyzed.Results:100% of students would recommend attending an organ retrieval to a colleague. Students strongly agreed that attending an organ retrieval was a useful learning experience (87.5%) and 90% of students felt more confident discussing organ donation with patients and relatives. 50% of students were more likely to pursue a career in transplant surgery. Students recognized a number of difficulties associated with the emotive impact of organ procurement.Conclusion:An organ retrieval program for medical students offers a novel learning opportunity, and may increase knowledge and improve attitudes toward transplantation in future healthcare professionals. However, the emotive impact of exposing students to organ retrievals must also be recognized.
      Citation: Progress in Transplantation
      PubDate: 2020-12-04T08:49:44Z
      DOI: 10.1177/1526924820978590
      Issue No: Vol. 31, No. 1 (2020)
       
  • Education Priorities and What Matters to Those Considering Living Kidney
           Donation
    • Authors: Kara Schick-Makaroff, Rebecca E. Hays, Julia Hunt, Laura A. Taylor, Dianne LaPointe Rudow
      Pages: 32 - 39
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 32-39, March 2021.
      Introduction:Although informed consent content elements are prescribed in detailed regulatory guidance, many live kidney donors describe feeling underprepared and under informed. The goal of this pilot study was to explore the educational components needed to support an informed decision-making process for living kidney donors.Methods/Approach:A qualitative description design was conducted with thematic analysis of 5 focus groups with 2 cohorts: living kidney donor candidates (n = 11) and living kidney donors (n = 8).Findings:The educational components needed to engage in an informed decision-making process were: 1) contingent upon, and motivated by, personal circumstances; 2) supported through explanation of risks and benefits; 3) enhanced by understanding the overall donation experience; and 4) personalized by talking to another donor.Discussion:Tailoring education to meet the needs for fully informed decision-making is essential. Current education requirements, as defined by regulatory bodies, remain challenging to transplant teams attempting to ensure fully informed consent of living kidney donor candidates. Information on the emotional, financial, and overall life impact is needed, along with acknowledgement of relational ties driving donor motivations and the hoped-for recipient outcomes. Discussion of care practices, and access to peer mentoring may further strengthen the informed decision-making process.
      Citation: Progress in Transplantation
      PubDate: 2020-12-10T09:40:40Z
      DOI: 10.1177/1526924820978599
      Issue No: Vol. 31, No. 1 (2020)
       
  • The Significance and Impact of Screening Preservation Fluid Cultures in
           Renal Transplant Recipients
    • Authors: Anesia Reticker, Alicia Lichvar, Meghan Walsh, Alan E. Gross, Shree Patel
      Pages: 40 - 46
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 40-46, March 2021.
      Introduction:Infectious complications can be a major cause of morbidity and mortality in solid organ transplant recipients. Preservation fluid is necessary to maintain organ viability but may serve as a vector or infection. The utility of screening preservation fluid routinely for microbial growth and the impact of culture-positive preservation fluid is controversial. Research Question: What is the clinical impact of a culture positive preservation fluid in a kidney transplant recipient'Design:This retrospective study was performed to define the incidence of post-operative infection related to PF and examine the negative sequelae of culture-positive PF. One hundred and fifty-two deceased donor renal transplant recipients from January 2015 to December 2017 were included for analysis.Results:Overall, 67% of patients (102/152) received an allograft from a culture-positive PF. Nearly 80% of microbial growth was consistent with skin flora, and coagulase-negative staphylococci was the most frequently isolated organism (56%). Sixty-seven percent of patients (68/102) with culture-positive PF received antimicrobial treatment for an average duration of 5 days. There was no difference in the incidence of infection between patients with culture positive PF compared to culture-negative PF. Furthermore, there were no cases of infection related to PF regardless of whether culture-positive PF was treated or untreated. The incidence of subsequent C. difficile infection and multidrug-resistant organisms was similar.Discussion:This study suggests antimicrobial treatment for culture positive PF may not be necessary with pathogens that are common contaminants and of low virulence. Interventional studies are needed to validate this strategy.
      Citation: Progress in Transplantation
      PubDate: 2020-12-10T09:41:40Z
      DOI: 10.1177/1526924820978608
      Issue No: Vol. 31, No. 1 (2020)
       
  • Preoperative Trapped Lung Is Associated With Increased Mortality After
           Orthotopic Liver Transplantation
    • Authors: Kathryn H. Melamed, David Dai, Natasha Cuk, Daniela Markovic, Robert Follett, Tisha Wang, Roxana Cortes Lopez, Aditya S. Shirali, Jane Yanagawa, Ronald Busuttil, Fady Kaldas, Igor Barjaktarevic
      Pages: 47 - 54
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 47-54, March 2021.
      Introduction:Trapped lung, characterized by atelectatic lung unable to reexpand and fill the thoracic cavity due to a restricting fibrous visceral pleural peel, is occasionally seen in patients with end-stage liver disease complicated by hepatic hydrothorax. Limited data suggest that trapped lung prior to orthotopic liver transplantation may be associated with poor outcomes.Research Question:What is the clinical significance of trapped lung in patients receiving orthotopic liver transplantation'Design:We performed a retrospective analysis of patients who underwent liver transplantation over an 8-year period. Baseline clinical characteristics and postoperative outcomes of adult patients with trapped lung were analyzed and compared to the overall cohort of liver transplant recipients and controls matched 3:1 based on age, sex, Model for End-Stage Liver Disease (MELD) score, and presence of pleural effusion.Results:Of the 1193 patients who underwent liver transplantation, we identified 20 patients (1.68%) with trapped lung. The probability of 1 and 2-year survival were 75.0% and 57.1%, compared to 85.6% and 80.4% (p = 0.02) in all liver transplant recipients and 87.9% and 81.1% (p = 0.03) in matched controls respectively. Patients with trapped lung had a longer hospital length of stay compared to the total liver transplant population (geometric mean 54.9 ± 8.4 vs. 27.2 ± 0.7 days, p ≤ 0.001), when adjusted for age and MELD score.Discussion:Patients with trapped prior to orthotopic liver transplantation have increased probability of mortality as well as increased health care utilization. This is a small retrospective analysis, and further prospective investigation is warranted.
      Citation: Progress in Transplantation
      PubDate: 2020-12-07T10:00:02Z
      DOI: 10.1177/1526924820978604
      Issue No: Vol. 31, No. 1 (2020)
       
  • The Living Donor Navigator Program Provides Support Tools for Caregivers
    • Authors: Rhiannon D. Reed, A. Cozette Killian, Margaux N. Mustian, Daagye H. Hendricks, Kimberly N. Baldwin, Vineeta Kumar, J. Nicholas Dionne-Odom, Kenneth Saag, Lisle Hites, Natalia V. Ivankova, Jayme E. Locke
      Pages: 55 - 61
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 55-61, March 2021.
      Introduction:The Living Donor Navigator (LDN) program is one of several initiatives designed to help transplant candidates identify living donors with the help of a friend or family member advocate to speak on their behalf. More than half of advocates in the LDN program were the spouse or parent of the candidate and served in a caregiving role. Caregivers for patients awaiting transplantation have reported poorer quality of life than the general population, suggesting more support is needed for this vulnerable group. The purpose of this study was to understand whether the LDN program met the needs of advocates who were also caregivers for the transplant candidate.Methods:We performed a supplementary secondary qualitative analysis of a parent study conducted December 2017-January 2018 with 9 advocates who participated in the LDN program. Transcripts were reanalyzed from focus group discussions, concentrating on comments about caregiving or made by caregivers. Using manual coding and reflexive thematic analysis, we identified broad codes and major themes.Findings:Our re-analysis revealed one theme overlapping with our previous analysis (Support) and 2 new themes specific to caregiver advocates: Quality of Life and Fear. Caregivers agreed that the LDN program equipped them with tools to address these areas and best serve their simultaneous caregiver/advocate roles.Discussion:These analyses demonstrated that those who served as advocate and caregiver derived a benefit from the LDN program but had distinct needs from other advocates. These findings can inform continued refinement of the program and expansion to support needs of caregiver
      Citation: Progress in Transplantation
      PubDate: 2020-12-23T09:39:34Z
      DOI: 10.1177/1526924820978598
      Issue No: Vol. 31, No. 1 (2020)
       
  • Factors Influencing Emergency Department Utilization and Hospital
           Re-Admissions in a Predominantly Obese, Racially Diverse Urban Renal
           Transplant Population
    • Authors: Alicia B. Lichvar, Alisha Patel, Dana Pierce, Renee Petzel Gimbar, Ivo Tzvetanov, Enrico Benedetti, Maya Campara
      Pages: 72 - 79
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 72-79, March 2021.
      Introduction:Early emergency department and hospital re-admissions are common in renal transplant recipients, but data are lacking in unique populations. Study Aim: The purpose of this study was to identify patient risk factors for multiple acute care utilization events within the first year of renal transplantation.Design:This was a single-center, retrospective cohort study of adult renal transplant recipients between 9/2013-9/2016. Patients were compared across number of emergency department visits and by hospital re-admissions. Diagnoses were categorized. Univariate and multivariate logistic regression was used to assess risk for multiple acute care utilization events within the first 12 months post-transplant.Results:A total of 216 patients were analyzed and were on average 50.5 (SD 13.9) years old, redominantly Black (49.77%) with an average body mass index of 33.33 (9.8) and were recipients of deceased donor renal transplants (61.11%). A total of 105 (48.6%) patients visited the emergency epartment and 119 (55.1%) patients had a hospital readmission. Patients having a body mass index >35 kg/m2 did not differ across emergency department visit or hospitalization groups. Delayed graft function (OR 2.86, 95% CI 1.07-7.65) and previous renal transplant (OR 2.77, 95% CI 1.04-7.39) were significantly associated with multiple acute care utilizations.Discussion:Acute care utilization following renal transplantation was similar to previously reported experiences. Obesity did not impact use of acute care resources or patient outcomes. Strategies addressing potential preventable emergency visits and hospital re-dmissions should be promoted.
      Citation: Progress in Transplantation
      PubDate: 2020-12-23T09:38:13Z
      DOI: 10.1177/1526924820978596
      Issue No: Vol. 31, No. 1 (2020)
       
  • Ventricular Assist Device Technology and Black-White Disparities on the
           Heart Transplant Wait List
    • Authors: Adrianne Frech, Jake Tarrence, Ginny Natale, Dmitry Tumin
      Pages: 80 - 87
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 80-87, March 2021.
      Introduction:Heart transplantation is the definitive treatment for end-stage heart failure. Left ventricular assist devices (LVADs) are a continually improving technology that extends life for some candidates on the heart transplant waiting list. Research Questions: Our objective is to compare Black-White differences in LVAD implantation and heart transplant outcomes during a period of technological innovation when the pulsatile flow LVAD was largely replaced by the continuous flow LVAD between 1999-2014.Design:We used transplant registry data from the United Network for Organ Sharing (N = 5,550) to identify Black and White patients with heart failure who used an LVAD as a bridge-to-transplant (BTT). Using logistic regression, we compared Black-White differences in access to newer LVAD technology and timing of implantation relative to wait listing for heart transplantation. We used competing-risks event history models to predict transplant outcomes across race, LVAD type, and timing of LVAD implantation.Results:Black and White candidates were equally likely to receive newer continuous flow LVADs, but Black candidates received LVADs later in the disease course (i.e. after transplant listing). This later timing of technological intervention contributed to poorer wait list outcomes among black transplant candidates, including lower likelihood of receiving a heart transplant and greater likelihood of being removed from the wait list due to worsening health.Discussion:Delayed LVAD implantation is more common among Black patients and is associated with poorer transplant outcomes.
      Citation: Progress in Transplantation
      PubDate: 2020-12-23T09:36:14Z
      DOI: 10.1177/1526924820978591
      Issue No: Vol. 31, No. 1 (2020)
       
  • Differentiating Depression From Demoralization in Organ Transplantation
           Recipients
    • Authors: Mary Rzeszut, Rachel Assael
      Pages: 88 - 90
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 88-90, March 2021.
      Living with end stage organ failure and transplantation has implications for physiological, psychological, and social well-being. The development of anxiety or depressive disorders are common with demoralization, another psychological syndrome, a topic of interest in psychiatry. To feel demoralized is to lose hope, courage, or confidence, which upsets normal functioning. While depression may co-exist with demoralization, they are 2 distinct entities, with the former characterized by an inability to experience pleasure and the latter characterized by helplessness and avoidance coping. In an effort to more adequately address the psychological stress in organ transplant patients, it is important to distinguish between demoralization and depression. Demoralization has prognostic implications such as negative disease outcomes such as treatment nonadherence and an increase risk of suicide. Medication for depression is not effective for demoralization syndrome. Therapeutic interventions include cognitive behavioral techniques that focus on exploration of attitudes toward hope and meaning in life.
      Citation: Progress in Transplantation
      PubDate: 2020-12-22T07:32:41Z
      DOI: 10.1177/1526924820978602
      Issue No: Vol. 31, No. 1 (2020)
       
  • Post-Cardiac Injury Following Liver Transplantation for Budd-Chiari
           Syndrome
    • Authors: Pamela Wong-Lucio, Pablo Moreno-Franco, Juan Canabal, Philip Lowman, Courtney Scott, Kristopher Croome, Ryan Chadha
      Pages: 91 - 92
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 91-92, March 2021.

      Citation: Progress in Transplantation
      PubDate: 2020-12-04T08:51:23Z
      DOI: 10.1177/1526924820978594
      Issue No: Vol. 31, No. 1 (2020)
       
  • Can Cytokine Serum Levels Be Useful With Kidney Transplantation and
           COVID-19'
    • Authors: Gian Luigi Adani, Riccardo Pravisani, Martina Fabris, Itzhak Avital, Francesco Curcio, Umberto Baccarani
      Pages: 93 - 94
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 93-94, March 2021.

      Citation: Progress in Transplantation
      PubDate: 2020-12-04T08:50:42Z
      DOI: 10.1177/1526924820978592
      Issue No: Vol. 31, No. 1 (2020)
       
  • Posttransplant Renal Lymphangiectasia Presents Differently From Native
           Kidneys and Warrants Attention
    • Authors: Roberta Pisano, Desirée Gianardi, Valerio Borrelli, Simone Guadagni, Alessandro Campatelli
      Pages: 95 - 96
      Abstract: Progress in Transplantation, Volume 31, Issue 1, Page 95-96, March 2021.

      Citation: Progress in Transplantation
      PubDate: 2020-12-15T09:38:56Z
      DOI: 10.1177/1526924820978595
      Issue No: Vol. 31, No. 1 (2020)
       
 
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