JournalTOCs

Geriatric Nephrology and Urology
Number of Followers: 7

Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0924-8455 - ISSN (Online) 1573-7306
Published by Springer-Verlag

[2468 journals]

Answering the Call… Again
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  Semin intervent Radiol 2021; 38: 509-510
  DOI: 10.1055/s-0041-1736528
  
  Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
  
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  Semin intervent Radiol 2021; 38: 509-5102021-11-24T00:00:00+0100
  Issue No: Vol. 38, No. 05 (2021)
Musculoskeletal Interventions: A Review on Genicular Artery Embolization
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  Authors: Sajan; Abin, Bagla, Sandeep, Isaacson, Ari
  Pages: 511 - 514
  Abstract: Symptomatic knee pain is one of the most common joint diseases that affects millions of people worldwide. The treatment for knee pain secondary to osteoarthritis (OA) begins with conservative therapy and progresses to surgical intervention when conservative therapy fails. Genicular artery embolization (GAE) offers an alternative option for patients who are poor surgical candidates. Multiple studies have been conducted worldwide demonstrating the safety and efficacy of GAE in patients with mild to moderate OA. The purpose of this article is to describe the current literature on GAE and highlight the latest findings from a randomized controlled trial comparing GAE versus sham embolization.
  Citation: Semin intervent Radiol 2021; 38: 511-514
  PubDate: 2021-11-24T00:00:00+0100
  DOI: 10.1055/s-0041-1736529
  Issue No: Vol. 38, No. 05 (2021)
A Review of Musculoskeletal Embolization to Treat Pain Outside of the Knee
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  Authors: Sajan; Abin, Bagla, Sandeep, Isaacson, Ari
  Pages: 515 - 517
  Abstract: Chronic inflammation leading to musculoskeletal pain has garnered interest in the past decade with the success of genicular artery embolization for knee pain secondary to osteoarthritis. Outside the knee joint, musculoskeletal embolization has been applied to other anatomical locations, mainly shoulder pain secondary to adhesive capsulitis and elbow pain secondary to lateral epicondylitis. The success of these early trials and other case reports highlights the efficacy of musculoskeletal embolization and its future potential.
  Citation: Semin intervent Radiol 2021; 38: 515-517
  PubDate: 2021-11-24T00:00:00+0100
  DOI: 10.1055/s-0041-1736530
  Issue No: Vol. 38, No. 05 (2021)
Endovascular Arteriovenous Fistula Creation: A Review
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  Authors: Tyagi; Ravi, Ahmed, S. Samaduddin, Navuluri, Rakesh, Ahmed, Osman
  Pages: 518 - 522
  Abstract: Endovascular arteriovenous fistula (endoAVF) creation offers a minimally invasive method for the formation of arteriovenous shunts utilized for hemodialysis. Currently, there exist two similar yet unique devices: WavelinQ and Ellipsys. This review analyzes the anatomy, pre- and postoperative considerations, fistula creation methods, and outcomes associated with endoAVF. Currently, data are limited with regard to clinical efficacy of endoAVFs when compared to surgical AVFs. However, early data suggest endoAVFs are a useful technique in the creation of AVFs.
  Citation: Semin intervent Radiol 2021; 38: 518-522
  PubDate: 2021-11-24T00:00:00+0100
  DOI: 10.1055/s-0041-1736531
  Issue No: Vol. 38, No. 05 (2021)
Stem Cell–Based Therapies: What Interventional Radiologists Need to
Know
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  Authors: Yu; Hyeon, Commander, Clayton W., Stavas, Joseph M.
  Pages: 523 - 534
  Abstract: As the basic units of biological organization, stem cells and their progenitors are essential for developing and regenerating organs and tissue systems using their unique self-renewal capability and differentiation potential into multiple cell lineages. Stem cells are consistently present throughout the entire human development, from the zygote to adulthood. Over the past decades, significant efforts have been made in biology, genetics, and biotechnology to develop stem cell–based therapies using embryonic and adult autologous or allogeneic stem cells for diseases without therapies or difficult to treat. Stem cell–based therapies require optimum administration of stem cells into damaged organs to promote structural regeneration and improve function. Maximum clinical efficacy is highly dependent on the successful delivery of stem cells to the target tissue. Direct image-guided locoregional injections into target tissues offer an option to increase therapeutic outcomes. Interventional radiologists have the opportunity to perform a key role in delivering stem cells more efficiently using minimally invasive techniques. This review discusses the types and sources of stem cells and the current clinical applications of stem cell–based therapies. In addition, the regulatory considerations, logistics, and potential roles of interventional Radiology are also discussed with the review of the literature.
  Citation: Semin intervent Radiol 2021; 38: 523-534
  PubDate: 2021-11-24T00:00:00+0100
  DOI: 10.1055/s-0041-1736657
  Issue No: Vol. 38, No. 05 (2021)
The Common but Complicated Tool: Review of Embolic Materials for the
Interventional Radiologist
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  Authors: Young; Shamar, Rostambeigi, Nassir, Golzarian, Jafar
  Pages: 535 - 541
  Abstract: Embolization is an important and widely utilized technique in interventional radiology. There are a variety of different categories and individual products which can be utilized to perform embolization. Understanding the different classes of embolic agents, the important features of each of these classes including strengths and limitations, and the variation in individual products within the classes is critical for interventional radiologist to practice safely and effectively. This article reviews the different kinds of embolics and relays some of the pertinent physical and chemical properties of individual products which should be considered when determining which embolic to select for a given purpose.
  Citation: Semin intervent Radiol 2021; 38: 535-541
  PubDate: 2021-11-24T00:00:00+0100
  DOI: 10.1055/s-0041-1736658
  Issue No: Vol. 38, No. 05 (2021)
Beyond the MAA-Y90 Paradigm: The Evolution of Radioembolization Dosimetry
Approaches and Scout Particles
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  Authors: Keane; Grace, Lam, Marnix, de Jong, Hugo
  Pages: 542 - 553
  Abstract: Radioembolization is a well-established treatment for primary and metastatic liver cancer. There is increasing interest in personalized treatment planning supported by dosimetry, as it provides an opportunity to optimize dose delivery to tumor and minimize nontarget deposition, which demonstrably increases the efficacy and safety of this therapy. However, the optimal dosimetry procedure in the radioembolization setting is still evolving; existing data are limited as few trials have prospectively tailored dose based on personalized planning and predominantly semi-empirical methods are used for dose calculation. Since the pretreatment or “scout” procedure forms the basis of dosimetry calculations, an accurate and reliable technique is essential. 99mTc-MAA SPECT constitutes the current accepted standard for pretreatment imaging; however, inconsistent patterns in published data raise the question whether this is the optimal agent. Alternative particles are now being introduced to the market, and early indications suggest use of an identical scout and treatment particle may be superior to the current standard. This review will undertake an evaluation of the increasingly refined dosimetric methods driving radioembolization practices, and a horizon scanning exercise identifying alternative scout particle solutions. Together these constitute a compelling vision for future treatment planning methods that prioritize individualized care.
  Citation: Semin intervent Radiol 2021; 38: 542-553
  PubDate: 2021-11-24T00:00:00+0100
  DOI: 10.1055/s-0041-1736660
  Issue No: Vol. 38, No. 05 (2021)
Challenges of Implementing Artificial Intelligence in Interventional
Radiology
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  Authors: Mazaheri; Sina, Loya, Mohammed F., Newsome, Janice, Lungren, Mathew, Gichoya, Judy Wawira
  Pages: 554 - 559
  Abstract: Artificial intelligence (AI) and deep learning (DL) remains a hot topic in medicine. DL is a subcategory of machine learning that takes advantage of multiple layers of interconnected neurons capable of analyzing immense amounts of data and “learning” patterns and offering predictions. It appears to be poised to fundamentally transform and help advance the field of diagnostic radiology, as heralded by numerous published use cases and number of FDA-cleared products. On the other hand, while multiple publications have touched upon many great hypothetical use cases of AI in interventional radiology (IR), the actual implementation of AI in IR clinical practice has been slow compared with the diagnostic world. In this article, we set out to examine a few challenges contributing to this scarcity of AI applications in IR, including inherent specialty challenges, regulatory hurdles, intellectual property, raising capital, and ethics. Owing to the complexities involved in implementing AI in IR, it is likely that IR will be one of the late beneficiaries of AI. In the meantime, it would be worthwhile to continuously engage in defining clinically relevant use cases and focus our limited resources on those that would benefit our patients the most.
  Citation: Semin intervent Radiol 2021; 38: 554-559
  PubDate: 2021-11-24T00:00:00+0100
  DOI: 10.1055/s-0041-1736659
  Issue No: Vol. 38, No. 05 (2021)
Understanding the Basics of Commonly Used Wires in Interventional
Radiology
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  Authors: Pandhi; Mithil B., Tyagi, Ravi, Surabhi, Divya, Shah, Ketan Y.
  Pages: 560 - 564
  Abstract: A wide variety of wires are available for use in interventional radiology, with wires demonstrating differences in construction, diameter, length, coating, shape, and taper. It is crucial to understand the difference in characteristics between these wires to select the most effective and safe wire for the intended purpose when undertaking a procedure. This article reviews the qualities and functions of different types of wires to aid in this decision-making process.
  Citation: Semin intervent Radiol 2021; 38: 560-564
  PubDate: 2021-11-24T00:00:00+0100
  DOI: 10.1055/s-0041-1739159
  Issue No: Vol. 38, No. 05 (2021)
Image-Guided Robotics for Standardized and Automated Biopsy and Ablation
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  Authors: Christou; Anna S., Amalou, Amel, Lee, HooWon, Rivera, Jocelyne, Li, Rui, Kassin, Michael T., Varble, Nicole, Tsz Ho Tse, Zion, Xu, Sheng, Wood, Bradford J.
  Pages: 565 - 575
  Abstract: Image-guided robotics for biopsy and ablation aims to minimize procedure times, reduce needle manipulations, radiation, and complications, and enable treatment of larger and more complex tumors, while facilitating standardization for more uniform and improved outcomes. Robotic navigation of needles enables standardized and uniform procedures which enhance reproducibility via real-time precision feedback, while avoiding radiation exposure to the operator. Robots can be integrated with computed tomography (CT), cone beam CT, magnetic resonance imaging, and ultrasound and through various techniques, including stereotaxy, table-mounted, floor-mounted, and patient-mounted robots. The history, challenges, solutions, and questions facing the field of interventional radiology (IR) and interventional oncology are reviewed, to enable responsible clinical adoption and value definition via ergonomics, workflows, business models, and outcome data. IR-integrated robotics is ready for broader adoption. The robots are coming!
  Citation: Semin intervent Radiol 2021; 38: 565-575
  PubDate: 2021-11-24T00:00:00+0100
  DOI: 10.1055/s-0041-1739164
  Issue No: Vol. 38, No. 05 (2021)
How I Do It: Computed Tomography–Guided Modified Translumbar
Embolization of Type 2 Endoleak
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  Semin intervent Radiol 2021; 38: 576-580
  DOI: 10.1055/s-0041-1736656
  
  Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
  
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  Semin intervent Radiol 2021; 38: 576-5802021-11-24T00:00:00+0100
  Issue No: Vol. 38, No. 05 (2021)
Percutaneous Balloon-Assisted Suprapubic Cystostomy Tube Placement: A
Novel Technique
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  Semin intervent Radiol 2021; 38: 581-583
  DOI: 10.1055/s-0041-1739160
  
  Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
  
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  Semin intervent Radiol 2021; 38: 581-5832021-11-24T00:00:00+0100
  Issue No: Vol. 38, No. 05 (2021)
Missed Gastroduodenal Hemorrhage: Breaking the Rules of Diagnostic Imaging
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  Semin intervent Radiol 2021; 38: 584-587
  DOI: 10.1055/s-0041-1739158
  
  Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
  
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  Semin intervent Radiol 2021; 38: 584-5872021-11-24T00:00:00+0100
  Issue No: Vol. 38, No. 05 (2021)
Management of Postprocedural Uterine Artery Embolization Pain
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  Semin intervent Radiol 2021; 38: 588-594
  DOI: 10.1055/s-0041-1739161
  
  Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
  
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  Semin intervent Radiol 2021; 38: 588-5942021-11-24T00:00:00+0100
  Issue No: Vol. 38, No. 05 (2021)
Principles of Radioembolization
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  Authors: Sivananthan; Gajan, Tabori, Nora E.
  Pages: 393 - 396
  Abstract: Radioembolization has become a mainstay therapy in the treatment of primary and secondary liver cancers. This article will specifically discuss a brief history of yttrium treatment as well as an overview of the physical properties of the currently available devices. A discussion of the mechanism of action will be followed by a discussion on patient selection for this treatment.
  Citation: Semin intervent Radiol 2021; 38: 393-396
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735606
  Issue No: Vol. 38, No. 04 (2021)
Current Approach to Planning Angiography and MAA Administration
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  Authors: Commander; Clayton W., Mauro, David M.
  Pages: 397 - 404
  Abstract: Transarterial radioembolization of primary and secondary hepatic malignancies utilizing yttrium-90 microspheres is a commonly performed treatment by interventional radiologists. Traditionally performed as a two-part procedure, a diagnostic angiography is performed 1 to 3 weeks prior to treatment with the injection of technetium-99m-macroaggregated albumin followed by planar scintigraphy in the nuclear medicine department. Careful attention must be paid to the details during the diagnostic angiography to ensure the delivery of a safe and optimal dose to the diseased liver and to minimize radiation-induced damage to both unaffected liver and adjacent structures. In this article, we will review the steps and considerations that must be made during the angiography planning and discuss current and future areas of research.
  Citation: Semin intervent Radiol 2021; 38: 397-404
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735616
  Issue No: Vol. 38, No. 04 (2021)
Standard Radiation Dosimetry Models: What Interventional Radiologists Need
to Know
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  Authors: Webster; Linzi Arndt, Villalobos, Alexander, Majdalany, Bill S., Bercu, Zachary L., Gandhi, Ripal T., Kokabi, Nima
  Pages: 405 - 411
  Abstract: Thoughtful and accurate dosimetry is critical to obtain the safest and most efficacious yttrium-90 (Y90) radioembolization of primary and secondary liver cancers. Three dosimetry models are currently used in clinical practice, namely, body surface area model, medical internal radiation dose model, and the partition model. The objective of this review is to briefly outline the history behind Y90 dosimetry and the difference between the aforementioned models. When applying these three models to a single case, the differences between them are further demonstrated. Each dosimetry model in clinical practice has its own benefits and limitations. Therefore, it is incumbent upon practicing interventional radiologists to be aware of these differences to optimize treatment outcomes for their patients.
  Citation: Semin intervent Radiol 2021; 38: 405-411
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1732323
  Issue No: Vol. 38, No. 04 (2021)
Lobar Radioembolization for Intermediate and Advanced Hepatocellular
Carcinoma: Retrospective and Prospective Data
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  Authors: Lakhoo; Janesh, Perez, Thomas H., Borgmann, Anthony J., Brown, Daniel B.
  Pages: 412 - 418
  Abstract: Historically, outcomes reporting for radioembolization with yttrium-90 (90Y) of hepatocellular carcinoma has included patients across the range of Barcelona Clinic Liver Cancer (BCLC) stages. With the potential for curative radiation segmentectomy for BCLC 0/A patients and evolution of systemic therapy for BCLC C patients, focused review by group is of increasing interest. In this review, we report on efficacy of 90Y in patients with intermediate (BCLC B) and advanced (BCLC C) hepatocellular carcinoma as well as expected toxicities. Additionally, we review existing trials comparing 90Y to transarterial chemoembolization and systemic treatments in these patient groups and outline future studies.
  Citation: Semin intervent Radiol 2021; 38: 412-418
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1733903
  Issue No: Vol. 38, No. 04 (2021)
Radiation Lobectomy: An Overview of Concept and Applications, Technical
Considerations, Outcomes
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  Authors: Entezari; Pouya, Gabr, Ahmed, Kennedy, Kristie, Salem, Riad, Lewandowski, Robert J.
  Pages: 419 - 424
  Abstract: Surgical resection has long been considered curative for patients with early-stage hepatocellular carcinoma (HCC). However, inadequate future liver remnant (FLR) renders many patients not amenable to surgery. Recently, lobar administration of yttrium-90 (Y90) radioembolization has been utilized to induce FLR hypertrophy while providing disease control, eventually facilitating resection in patients with hepatic malignancy. This has been termed “radiation lobectomy (RL).” The concept is evolving, with modified approaches combining RL and high-dose curative-intent radioembolization (radiation segmentectomy) to achieve tumor ablation. This article provides an overview of the concept and applications of RL, including technical considerations and outcomes in patients with hepatic malignancies.
  Citation: Semin intervent Radiol 2021; 38: 419-424
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735530
  Issue No: Vol. 38, No. 04 (2021)
Radiation Segmentectomy
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  Authors: Prachanronarong; Kristina, Kim, Edward
  Pages: 425 - 431
  Abstract: Radiation segmentectomy is an yttrium-90 transarterial radioembolization treatment where a high radiation dose is administered to a small volume of liver to achieve a high tumoricidal dose to a target with anatomic surgical precision while sparing surrounding parenchyma. This therapeutic modality is often used to treat hepatocellular carcinoma, and recent studies have demonstrated that radiation segmentectomy is an effective treatment as a neoadjuvant to transplant, resection, or as a standalone treatment. This article provides a review of radiation segmentectomy, indications for treatment, recent outcome data, and guidelines for postprocedural management.
  Citation: Semin intervent Radiol 2021; 38: 425-431
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735529
  Issue No: Vol. 38, No. 04 (2021)
Contemporary Algorithm for the Management of Hepatocellular Carcinoma in
2021: The Northwestern Approach
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  Authors: Swersky; Adam, Kulik, Laura, Kalyan, Aparna, Grace, Karen, Caicedo, Juan Carlos, Lewandowski, Robert J., Salem, Riad
  Pages: 432 - 437
  Abstract: Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a major cause of cancer-related morbidity and mortality around the world. Frequently, concurrent liver dysfunction and variations in tumor burden make it difficult to design effective and standardized treatment pathways. Contemporary treatment guidelines designed for an era of personalized medicine should consider these features in a more clinically meaningful way to improve outcomes for patients across the HCC spectrum. Given the heterogeneity of HCC, we propose a detailed clinical algorithm for selecting optimal treatment using an evidence-based and practical approach, incorporating liver function, tumor burden, the extent of disease, and ultimate treatment intent, with the goal of individualizing clinical decision making.
  Citation: Semin intervent Radiol 2021; 38: 432-437
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735528
  Issue No: Vol. 38, No. 04 (2021)
Radioembolization of Intrahepatic Cholangiocarcinoma: Patient Selection,
Outcomes, and Competing Therapies
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  Authors: Ness; Joseph Ray, Molvar, Christopher
  Pages: 438 - 444
  Abstract: Intrahepatic cholangiocarcinoma is the second most common primary hepatic malignancy and poses a therapeutic challenge owing to its late-stage presentation and treatment-resistant outcomes. Most patients are diagnosed with locally advanced, unresectable disease and are treated with a combination of systemic and local regional therapies. Transarterial radioembolization offers a survival benefit and a favorable side effect profile, with a growing body of evidence to support its use. Herein, we review patient selection and detail outcomes of radioembolization for intrahepatic cholangiocarcinoma, together with mention of competing treatments.
  Citation: Semin intervent Radiol 2021; 38: 438-444
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735526
  Issue No: Vol. 38, No. 04 (2021)
Radioembolization of Secondary Hepatic Malignancies
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  Authors: Manchec; Barbara, Kokabi, Nima, Narayanan, Govindarajan, Niekamp, Andrew, Peña, Constantino, Powell, Alex, Schiro, Brian, Gandhi, Ripal
  Pages: 445 - 452
  Abstract: Cancer has become the leading cause of mortality in America, and the majority of patients eventually develop hepatic metastasis. As liver metastases are frequently unresectable, the value of liver-directed therapies, such as transarterial radioembolization (TARE), has become increasingly recognized as an integral component of patient management. Outcomes after radioembolization of hepatic malignancies vary not only by location of primary malignancy but also by tumor histopathology. This article reviews the outcomes of TARE for the treatment of metastatic colorectal cancer, metastatic breast cancer, and metastatic neuroendocrine tumors, as well as special considerations when treating metastatic disease with TARE.
  Citation: Semin intervent Radiol 2021; 38: 445-452
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1732318
  Issue No: Vol. 38, No. 04 (2021)
Recognizing and Managing Adverse Events in Y-90 Radioembolization
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  Authors: Laidlaw; Grace L., Johnson, Guy E.
  Pages: 453 - 459
  Abstract: Transarterial radioembolization using yttrium-90 (Y-90) microspheres is an important therapy in the management of unresectable primary liver tumors or hepatic metastases. While radioembolization is generally well-tolerated, it is not free from adverse events, and familiarity with the prevention and treatment of radioembolization-specific complications is an important component of patient care. This article aims to review radioembolization-specific toxicities stratified by hepatic, extrahepatic, and systemic effects, with a focus on preventing and mitigating radioembolization-induced morbidity.
  Citation: Semin intervent Radiol 2021; 38: 453-459
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735617
  Issue No: Vol. 38, No. 04 (2021)
Post Yttrium-90 Imaging
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  Authors: Rice; Mitchell, Krosin, Matthew, Haste, Paul
  Pages: 460 - 465
  Abstract: Transarterial radioembolization with yttrium-90 (90Y) is a mainstay for the treatment of liver cancer. Imaging the distribution following delivery is a concept that dates back to the 1960s. As β particles are created during 90Y decay, bremsstrahlung radiation is created as the particles interact with tissues, allowing for imaging with a gamma camera. Inherent qualities of bremsstrahlung radiation make its imaging difficult. SPECT and SPECT/CT can be used but suffer from limitations related to low signal-to-noise bremsstrahlung radiation. However, with optimized imaging protocols, clinically adequate images can still be obtained. A finite but detectable number of positrons are also emitted during 90Y decay, and many studies have demonstrated the ability of commercial PET/CT and PET/MR scanners to image these positrons to understand 90Y distribution and help quantify dose. PET imaging has been proven to be superior to SPECT for quantitative imaging, and therefore will play an important role going forward as we try and better understand dose/response and dose/toxicity relationships to optimize personalized dosimetry. The availability of PET imaging will likely remain the biggest barrier to its use in routine post-90Y imaging; thus, SPECT/CT imaging with optimized protocols should be sufficient for most posttherapy subjective imaging.
  Citation: Semin intervent Radiol 2021; 38: 460-465
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735569
  Issue No: Vol. 38, No. 04 (2021)
Radioembolization for the Treatment of Hepatocellular Carcinoma: The Road
to Personalized Dosimetry and Ablative Practice
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  Authors: De la Garza-Ramos; Cynthia, Toskich, Beau B.
  Pages: 466 - 471
  Abstract: Radioembolization dosimetry for the treatment of hepatocellular carcinoma has evolved alongside our understanding of best practice for this therapy. At the core of advances in dosimetry are personalized and ablative applications of radioembolization, which have generated paradigm shifts in both safety and efficacy. This review provides a summary of fundamental radioembolization dosimetry concepts and narrates how our approach to treating patients has shifted from conventional to tailored and definitive therapy.
  Citation: Semin intervent Radiol 2021; 38: 466-471
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735571
  Issue No: Vol. 38, No. 04 (2021)
Radioembolization in the Setting of Systemic Therapies
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  Authors: Mabud; Tarub S., Hickey, Ryan
  Pages: 472 - 478
  Abstract: 90Yttrium (Y90) radioembolization has been shown to improve outcomes for primary and metastatic liver cancers, but there is limited understanding of the optimal timing and safety of combining systemic therapies with Y90 treatment. Both therapeutic effects and toxicities could be synergistic depending on the timing and dosing of different coadministration paradigms. In particular, patients with liver-only or liver-dominant metastatic disease progression are often on systemic therapy when referred to interventional radiology for consideration of Y90 treatment. Interventional radiologists are frequently asked to offer insight into whether or not to hold systemic therapy, and for how long, prior to and following transarterial therapy. This study reviews the current evidence regarding the timing and safety of systemic therapy with Y90 treatment for hepatocellular carcinoma, metastatic colorectal carcinoma, intrahepatic cholangiocarcinoma, metastatic neuroendocrine tumors, and other hepatic metastases. A particular focus is placed on the timing, dosing, and toxicities of combined therapy.
  Citation: Semin intervent Radiol 2021; 38: 472-478
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735572
  Issue No: Vol. 38, No. 04 (2021)
Extrahepatic Applications of Yttrium-90 Radioembolization
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  Authors: Murali; Nikitha, Mouli, Samdeep K., Riaz, Ahsun, Lewandowski, Robert J., Salem, Riad
  Pages: 479 - 481
  Abstract: While initially described and now accepted as treatment for primary and secondary malignancies in the liver, radioembolization therapy has expanded to include treatment for other disease pathologies and other organ systems. Advantages and limitations for these treatments exist and must be compared against more traditional treatments for these processes. This article provides an overview of the current applications for radioembolization outside of the liver, for both malignant and nonmalignant disease.
  Citation: Semin intervent Radiol 2021; 38: 479-481
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735573
  Issue No: Vol. 38, No. 04 (2021)
Quality of Life and Cost Considerations: Y-90 Radioembolization
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  Authors: Williams; Stephen J., Rilling, William S., White, Sarah B.
  Pages: 482 - 487
  Abstract: Objective Transarterial radioembolization (TARE) offers a minimally invasive and safe treatment option for primary and metastatic hepatic malignancies. The benefits of TARE are manifold including prolonged overall survival, low associated morbidities, and improved time to progression allowing prolonged treatment-free intervals. The rapid development of new systemic therapies including immunotherapy has radically changed the treatment landscape for primary and metastatic liver cancer. Given the current climate, it is critical for interventional oncologists to understand the benefits of TARE relative to these other therapies. Therefore, this report aims to review quality-of-life outcomes and the cost comparisons of TARE as compared with systemic therapies.
  Citation: Semin intervent Radiol 2021; 38: 482-487
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735570
  Issue No: Vol. 38, No. 04 (2021)
Biliary-Caval Fistula following Y90 Radioembolization
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  Authors: Hall; Alexander D., White, Sarah B., Rilling, William S.
  Pages: 488 - 491
  Abstract: The safety of radioembolization with yttrium-90 (90Y) is well documented and major complications are rare. Previous studies have demonstrated that biliary complications following 90Y, including bile duct injury and hepatic abscess formation, occur at an increased rate in patients who have had prior biliary surgery and interventions. This article reviews a case of a patient who developed recurrent cholangitis and sepsis as well as a biliary-caval fistula following radioembolization. Additionally, we review current data regarding biliary complications following radioembolization in patients with prior biliary intervention.
  Citation: Semin intervent Radiol 2021; 38: 488-491
  PubDate: 2021-10-07T00:00:00+01:00
  DOI: 10.1055/s-0041-1735605
  Issue No: Vol. 38, No. 04 (2021)
Infrapopliteal Artery Chronic Total Occlusion Crossing Techniques: An
Overview for Endovascular Specialists
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  Semin intervent Radiol 2021; 38: 492-499
  DOI: 10.1055/s-0041-1735607
  
  Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
  
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  Semin intervent Radiol 2021; 38: 492-4992021-10-07T00:00:00+01:00
  Issue No: Vol. 38, No. 04 (2021)
Disability in Interventional Radiology
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  Semin intervent Radiol 2021; 38: 500-503
  DOI: 10.1055/s-0041-1735604
  
  Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
  
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  Semin intervent Radiol 2021; 38: 500-5032021-10-07T00:00:00+01:00
  Issue No: Vol. 38, No. 04 (2021)
Understanding the Basics of Commonly Used Wires in Interventional
Radiology
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  Semin intervent Radiol 2021; 38: 504-508
  DOI: 10.1055/s-0041-1735611
  
  Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
  
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  Semin intervent Radiol 2021; 38: 504-5082021-10-07T00:00:00+01:00
  Issue No: Vol. 38, No. 04 (2021)

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