JournalTOCs

Journal of Clinical Urology
Journal Prestige (SJR): 0.15

Number of Followers: 13

Hybrid journal (It can contain Open Access articles)
ISSN (Print) 2051-4158 - ISSN (Online) 2051-4166
Published by Sage Publications

[1176 journals]

Jo Cresswell Introduction
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Pages: 2 - 3
  Abstract: Journal of Clinical Urology, Volume 17, Issue 1_suppl, Page 2-3, June 2024.
  
  Citation: Journal of Clinical Urology
  PubDate: 2024-06-24T11:39:53Z
  DOI: 10.1177/20514158241252244
  Issue No: Vol. 17, No. 1_suppl (2024)
Abstract Book_BAUS 2024
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Pages: 4 - 102
  Abstract: Journal of Clinical Urology, Volume 17, Issue 1_suppl, Page 4-102, June 2024.
  
  Citation: Journal of Clinical Urology
  PubDate: 2024-06-24T11:39:52Z
  DOI: 10.1177/20514158241252246
  Issue No: Vol. 17, No. 1_suppl (2024)
A clinician survey on the current practices within the prostate cancer
diagnostic pathway in the United Kingdom
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Uma Walters, Mathias Winkler, Rakesh Heer, Andrea Rockall, Rhian Gabe, Hashim U Ahmed, Taimur T Shah
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objectives:To assess current clinical practice of prostate biopsies among UK Urologists and Radiologists, to guide future strategy with regard to diagnostic studies.Methods:An online questionnaire was administered to 210 UK Urologists and Radiologists, between January 2020 and December 2020.Results:124 responded (59%); urologists (55/77, 71.4%) and radiologists 22/77 (28.5%). 63/76 (83%) clinicians routinely use prebiopsy multiparametric magnetic resonance imaging (mpMRI) and 13/76 (17.1%) use bpMRI. For an MRI PI-RADS 1-2 score, 96% of clinicians would proceed to prostate biopsy with at least one additional risk factor. For an MRI PI-RADS 3 score, 48.6% would proceed to prostate biopsy with one additional risk factor, while 35.7% would perform a biopsy in all patients. 17.7% would proceed to prostate biopsy with a PSAD ⩽ 0.12 ng/mL/mL even in patients with a PI-RADS 1–2 lesion and 82.4% would for PI-RADS 3 lesions. Transperineal biopsies were most commonly performed (63/72, 88%). Up to nine systematic cores was most common (25/68, 36.8%) with three to four targeted cores (37%). 66/67 (98.5%) of clinicians would be willing to accept a standard operating procedure for participants in an RCT study (with regard to biopsy strategy).Conclusion:Our study has provided a glimpse into current UK practice to diagnose patients with prostate cancer and provides evidence for future RCT study designs.
  Citation: Journal of Clinical Urology
  PubDate: 2024-08-03T08:35:21Z
  DOI: 10.1177/20514158241267083
Outcomes of type 1 versus type 2 papillary renal cell carcinoma following
surgery: A 20-year experience
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Morgan Black, Courtney Yong, James E Slaven, Kingsley Ebare, Muhammad T Idrees, Ronald Boris, Chandru P Sundaram
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Introduction:Papillary renal cell carcinoma (PRCC) is the second most common type of renal cell carcinoma. Although studies have explored the connection between PRCC subtype and disease prognosis, the evidence is conflicting. We compared oncologic outcomes of type 1 and 2 PRCCs following surgical management.Methods:A single-centre, retrospective review identified patients undergoing surgery for PRCC from 2000 to 2022. Demographic, imaging, staging pathology, and follow-up data were collected. Recurrence-free, cancer-specific, and overall survival (RFS, CSS, OS) were calculated using the Kaplan-Meier method and Cox proportional hazard ratio.Results:A total of 249 patients were identified. Of the total, 177 patients had type 1 PRCC, and 72 had type 2. The average age was 62 years and was similar between groups (p = 0.66). The median RENAL score was 7 for both groups (p = 0.12). Type 2 had a higher pathologic T-stage with fewer pT1 (58% vs 86%) and more pT3 masses (32% vs 7%) than type 1 (p
  Citation: Journal of Clinical Urology
  PubDate: 2024-07-28T06:29:10Z
  DOI: 10.1177/20514158241266065
Cystolitholapaxy for large-volume bladder stones using Swiss LithoClast
TrilogyⓇ: Initial clinical experience
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: George Sturgess, Ian Beckley, Alison Downey, Rebecca Phillips, Xenia Sara, George Wilcox, Matthew Young, Stephanie Symons
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objective:Large bladder calculi can be managed with open cystolithotomy, or endoscopically through cystolitholapaxy. The Swiss LithoClast Trilogy is a single-probe dual-energy lithotripter, widely used in percutaneous nephrolithotomy (PCNL). We report our clinical experience including the safety and efficacy of using Trilogy for cystolitholapaxy.Patients and Methods:Patients undergoing cystolitholapaxy using Trilogy since 2020 were identified, and data collected included stone profile, operative details, complications and stone-free status. Radiological stone characterisation was performed for all patients undergoing computed tomography (CT) imaging pre-operatively.Results:There were 41 cystolitholapaxy procedures performed using Trilogy. Average age was 65 years, and 85.4% were male. Average total stone volume was 13.7 cm3 (SD ±14.6 cm3). The largest stone cleared had a maximal diameter of 4.9 cm and volume of 46.1 cm3. Transurethral access via a nephroscope was used in 38 of 41 (92.7%) cases. Average total operating time was 89 minutes (SD ± 40 minutes), and average length of stay was 1.35 days (SD ±2.41 days). Two complications not directly attributable to the use of Trilogy occurred.Conclusion:Cystolitholapaxy using Trilogy is both safe and effective in treating large-volume bladder stones with high complete clearance rates and an excellent safety profile. It should be considered as an alternative to open cystolithotomy.Level of evidence:4
  Citation: Journal of Clinical Urology
  PubDate: 2024-07-27T07:02:39Z
  DOI: 10.1177/20514158241266061
Editorial July
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Abstract: Journal of Clinical Urology, Ahead of Print.
  
  Citation: Journal of Clinical Urology
  PubDate: 2024-07-27T06:56:40Z
  DOI: 10.1177/20514158241265225
ChatGPT sitting for FRCS Urology examination: Will artificial intelligence
get certified'
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Elsayed Desouky, Samer Jallad, Jeetesh Bhardwa, Harbinder Sharma, Jas Kalsi
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Introduction:The use of artificial intelligence (AI), including neural networks and deep learning, has rapidly changed many industries. One recent application of AI that has gained the attention of physicians and the general public alike is ChatGPT, a chatbot developed and released by OpenAI Inc. in November2022. We challenged ChatGPT to sit the Fellowship of the Royal College of Surgeons (FRCS) Urology examination, both parts, to assess its performance and determine its eligibility for the title.Methods:We prepared a set of 100 Multiple-Choice Questions (MCQs) for Part 1 and 8 viva scenarios for Part 2. We choose to use ChatGPT 3.5 that is the free version available online, and responses were documented during the simulation.Results:In Part 1 MCQs, Chat Generative Pre-trained Transformer (ChatGPT) managed to answer some questions correctly with an overall score of 35%. However, in Part 2 Viva, its performance improved to an extent, demonstrating proficiency by offering detailed explanations and reasoning, achieving average score in some stations. ChatGPT’s performance raised some concerns on answering questions.Conclusion:AI is definitely an asset that can be used in our daily practice, yet it is crucial to take into consideration the concerns about the accuracy of data provided, including AI hallucination. ChatGPT failed to get the FRCS Urology title this time. Still in the early stages of development, further research is necessary to comprehensively understand their limitations and capabilities.Level of evidence:Not applicable
  Citation: Journal of Clinical Urology
  PubDate: 2024-07-24T08:56:51Z
  DOI: 10.1177/20514158241262081
Current peri-operative and surgical management of bladder paraganglioma
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Sammy Gharbieh, Niyati Lobo, Anand Velusamy, Jamie McCanny, Ramesh Thurairaja, Muhammad Shamim Khan, Rajesh Nair
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Introduction:In this article, we provide a narrative review of current peri-operative and surgical management of paraganglioma of the urinary bladder (PUB).Methods:Key articles relating to peri-operative optimisation, intra-operative considerations and post-operative follow-up of patients with PUB were identified for review.Discussion:Although the majority of PUBs are functionally active with potential for catecholamine release, typical catecholaminergic symptoms are often overshadowed by the presence of lower urinary tract symptoms such as painless visible haematuria. Consequently, many cases are diagnosed based on post-operative histopathology, resulting in inferior short- and long-term outcomes. Accurate pre-operative diagnosis is crucial as this informs pre-operative optimisation and choice of surgical approach. Partial cystectomy is the mainstay of treatment, but transurethral resection may be appropriate for non-functional tumours
  Citation: Journal of Clinical Urology
  PubDate: 2024-06-24T06:18:03Z
  DOI: 10.1177/20514158241262086
Recommendations of Clinical Practice Guidelines for the treatment of
urinary incontinence in women: A methodological survey
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Mariana Del Grossi Moura, Flávia Blaseck Sorrilha, Gabriela Magnusson, Silvio Barberato-Filho, Luciane Cruz Lopes, Glasiela Isabele Camargo Pereira, Cristiane de Cássia Bergamaschi
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objective:This study described and analysed key recommendations from Clinical Practice Guidelines (CPGs) concerning urinary incontinence (UI) treatment in women.Materials and methods:We carried out searches in the following databases: MEDLINE, EMBASE, Web of Science, Virtual Health Library, among others. The reviewers, in duplicate and independently, selected the documents and extracted the data. The quality assessment of the guidelines was carried out, in triplicate, using the Appraisal of Guidelines REsearch and Evaluation (AGREE II) instrument.Results:Six CPGs were selected for analysis. Pelvic Floor Muscle Training (PFMT) is the primary treatment for UI, with adjunctive therapies (biofeedback, vaginal cones, dynamic lumbopelvic stabilisation, and electrical stimulation) recommended alongside PFMT. Discrepancies among CPG were noted in recommendations for drug treatments and invasive procedures, suggesting the need for individualised approaches. When conservative non-pharmacological treatments failed, drugs are recommended. Mid-urethral slings were endorsed, with alternatives like colposuspension or autologous rectus fascial slings considered when mid-urethral slings were unsuitable. Botulinum toxin type A was suggested for urge UI patients unresponsive to conservative therapy.Conclusion:UI treatment must prioritise the conservative non-pharmacological therapies and progressing to invasive options, as necessary. These evidence-based findings aim to guide patients, healthcare professionals, and policy managers in effectively managing UI.Level of evidence:Not applicable
  Citation: Journal of Clinical Urology
  PubDate: 2024-05-17T11:19:40Z
  DOI: 10.1177/20514158241251630
Assessing the efficacy of clinical triage in the prostate cancer best
practice pathway
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Charlotte Roberts, Sophie Vaggers, Linda Martin, Denise Elson, Alexandra Noble, Karen Carrinton, James Dyer
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objective:The Prostate Cancer UK timed prostate cancer diagnostic pathway is a new UK pathway to deliver a diagnosis within 28 days for patients with suspected prostate cancer. We aim to review our experience of implementing this pathway, in particular the success of clinical triage.Subjects/patients (or materials) and methods:We reviewed consecutive referrals to the prostate cancer best timed pathway from September 2019 to September 2020. Patients were triaged either straight to test multiparametric magnetic resonance imaging (mpMRI) or straight to outpatient clinic. Inappropriate triage was defined as either: patients referred straight to test mpMRI who were diagnosed with prostate cancer and managed with watchful waiting or androgen deprivation therapy (ADT) or patients who were referred straight to clinic who subsequently had an mpMRI and underwent radical treatment.Results:A total of 154/155 (99.6%) of patients were appropriately triaged in the straight to mpMRI group. A total of 124/132 (94.0%) of patients were appropriately triaged in the straight to clinic group (patients who required review to ascertain if mpMRI was appropriate and then received radical treatment).Conclusion:The implementation of a consultant supervised triage process has been successful in avoiding unnecessary mpMRIs or unnecessary clinic appointments before a patient received a diagnosis or reassuring test. We advise that outcomes are audited regularly to ensure the effective use of resources.Level of evidence:2C
  Citation: Journal of Clinical Urology
  PubDate: 2024-05-14T11:50:53Z
  DOI: 10.1177/20514158241247090
Sustainability in endourology: Greening the stone theatre and beyond
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Sara Ramsey
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objective:Climate change has been described as the ‘biggest global health threat of the 21st century’ and NHS England has set out its plans to develop a ‘net zero’ NHS by 2040. This is a target of completely negating the amount of greenhouse gases produced by healthcare in the United Kingdom, currently estimated at 4% of the UK total carbon emissions. We need to consider as a community of endourologists how we can make sustainable choices.Methods:Recommendations for sustainable surgery in the United Kingdom have been considered and applied to the field of Endourology. There is a relatively little published evidence on this evolving area.Results:Areas for making sustainable choices in Endourology can broadly be divided into ‘Prevention and Education’, ‘Pre-operative’, ‘Planning’, ‘Operative’ and ‘After Care’. While reducing waste in theatre is clearly important, there are many other decisions we can make with our patients to create a lower carbon journey.Conclusion:Sustainability in Endourology strongly parallels GIRFT recommendations and the concept of realistic medicine. We should all make personal and professional choices to reduce our carbon footprint with the shared goal of Net zero in 2040.Level of evidence:4
  Citation: Journal of Clinical Urology
  PubDate: 2024-04-28T07:30:15Z
  DOI: 10.1177/20514158241246038
Ureteroscopic treatment of urolithiasis: How do we measure and optimise
outcomes'
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Daron Smith, Sabrina Helena Rossi, Yuko Smith, Amelia Pietropaolo, Hrishi Joshi, Hari Ratan
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Background:Patients with urolithiasis have access to a wide range of efficacious therapeutic surgical options, including shockwave lithotripsy (SWL), retrograde ureteric or intrarenal surgery with semi-rigid and flexible ureteroscopes (URS or fURS) and percutaneous nephrolithotomy (PCNL). In recent years, there have been many peer-reviewed publications evaluating new techniques and new equipment, such as pulse-modulated Holmium:YAG and thulium fibre lasers. However, when reviewing this extensive literature, it becomes apparent that there is no consensus on what constitutes a ‘successful’ stone treatment outcome.Objectives:The purpose of this article is to review the existing measures of ‘success’ after the ureteroscopic treatment of urolithiasis and to promote a standardised and holistic approach to reporting outcomes in clinical trials.Methods:Our narrative review focussed on studies examining measures of success in urolithiasis treatment published within the last 10 years.Conclusions:Due to markedly different reported outcome measures of treatments for urolithiasis, comparing results between studies can be difficult. In addition to measuring clinical outcomes, there is an increasing acknowledgement of the importance of patient-reported outcome measures (PROMs) in determining treatment success, and the need to consider the cost-effectiveness and environmental sustainability of various treatments. We suggest that all future studies on this common urological condition should incorporate holistic and tranpsarent outcome measures.Level of evidence:Not applicable
  Citation: Journal of Clinical Urology
  PubDate: 2024-04-18T12:02:15Z
  DOI: 10.1177/20514158241237278
Nurse-led UTI service provides consistent care and reduces pressure on
consultant clinics
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Supun De Silva, Mustafa Rashid, Coral Seymour, Paulette Hussain, Maike Eylert
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objectives:To publish the five-year outcomes of the nurse-led urinary tract infection (UTI) clinic, which is the first-ever outpatient nurse-led service for women with recurrent urinary tract infections.Materials and Methods:This report is on a single UK centre review of outcomes including patients seen in a nurse-led UTI clinic between January 2017 and December 2021.Results:A total of 1425 patients were audited. The median wait from referral time was 18 weeks. Standard ultrasound of kidneys, ureter and bladder (KUB) was offered to most patients which detected an abnormality in 17.5% (n = 240/1374) of scans, and flexible cystoscopy (selective) was positive in 11.9% (n = 46/386) mainly for benign pathologies. At 6 months, 80.6% of patients were discharged, with only 10.9% of patients requiring referral to the consultant urology clinic. Four urothelial cancers were picked up in the absence of red-flag symptoms on the referral, each one much quicker than the average wait for general consultant clinics at the point of referral.Conclusions:A well-run, protocol-driven nurse-led UTI clinic provides consistent care to women with recurrent UTIs. More than 80% of patients can be successfully discharged at 6 months which reduces pressure on consultant clinics.Level of evidence:Not applicable
  Citation: Journal of Clinical Urology
  PubDate: 2024-04-15T05:54:08Z
  DOI: 10.1177/20514158241245825
A short history of the British Urology Researchers in Surgical Training
(BURST): The power of collaborative research
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Quentin Mak, Kevin Gerard Byrnes, Arjun Nathan, Nikki Kerdegari, Sinan Khadhouri, Nikita Bhatt, Veeru Kasivisvanathan
  Abstract: Journal of Clinical Urology, Ahead of Print.
  The British Urology Researchers in Surgical Training (BURST) is a UK-based, trainee-led urology research collaborative. Since inception in 2014, BURST has led projects in several urological subspecialties with the aim of improving urological practice for patient benefit. Key innovations we have used include an emphasis on social media communications and developing innovative technology solutions to improve collaboration. In this review article, we summarise our recent studies and highlight important strategies for performing collaborative research.Level of evidence: Not applicable.
  Citation: Journal of Clinical Urology
  PubDate: 2024-04-11T07:23:03Z
  DOI: 10.1177/20514158241242970
Advances in HoLEP technology and technique – Current state of play
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Nicholas S Dean, Jega Thiruchelvam, Jenny N Guo, Jordan Durrant, Amy E Krambeck, Tevita F Aho
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Background:Until recently, Holmium laser enucleation of the prostate (HoLEP) utilisation has been limited despite its perceived benefits over alternative surgical and minimally invasive benign prostatic hyperplasia (BPH) treatments.Objective:The purpose of this review is to highlight our experience with recent advances in laser and morcellator technologies that have made it easier for urologists to consistently offer HoLEP as a safe, efficient, and effective in an ambulatory (day surgery) setting.Methods:Our narrative review focused on contemporary studies published within the last five years.Conclusions:Technological advances coupled with increasing availability of training opportunities has and will continue to improve patients’ accessibility to the gold standard in BPH surgical treatment. Furthermore, we will describe refinements in laser enucleation techniques that have improved procedural efficiencies, rates of temporary post-operative urinary incontinence, and preservation of sexual function. The effects of technical modifications on functional and durability outcomes are to be seen in further prospective studies.Level of Evidence:Level 7 (Expert Opinion)
  Citation: Journal of Clinical Urology
  PubDate: 2024-04-09T04:48:47Z
  DOI: 10.1177/20514158241242961
A retrospective study on the management of ureteric stones following
presentation to the emergency department in the University Hospitals
Sussex Trust East from November 2020 to November 2021
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Ava Rietdyk, Paimaun Zakikhani, Andrew Symes
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objective:To ascertain which patient demographic, clinical and stone-specific factors were significant when predicting intervention for ureteric stones and determine the proportion of patients with smaller, more distally located stones requiring intervention to establish whether follow-up imaging was indicated to confirm stone passage.Subjects/patients and methods:This is a retrospective review of 227 patients presenting with ureteric stones on non-contrast computerised tomography (NCCT) between November 2020 and November 2021. Eleven different clinical, demographic and imaging-related factors were recorded, and multivariate logistical regression was used to determine which factors were significant when predicting intervention.Results:A total of 53 patients (23.3%) underwent some form of intervention with only stone size (p < 0.001) and stone location (p < 0.001) significant in predicting treatment. Only 4.17% of patients with a ⩽ 4 mm distally located stone required intervention. These patients either had raised inflammatory markers or significant pain.Conclusion:Given that 95.83% of patients with ⩽ 4 mm distal ureteric calculi passed their stone spontaneously, a patient-initiated follow-up (PIFU) could be implemented to replace a follow-up NCCT. Based on this dataset, the application of PIFU could have prevented additional radiation exposure of 1.5–3 mSv/patient and excess financial cost of approximately £7000 to services.Level of Evidence:Level 3
  Citation: Journal of Clinical Urology
  PubDate: 2024-04-05T06:57:48Z
  DOI: 10.1177/20514158241241195
Day case Rezum™ water vapour therapy for urinary retention secondary to
benign prostatic hyperplasia
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Mohamed Noureldin, Omar Alabed Allat, Ramzy Elnabarawy, Mohamed Alnoomani, Yehia Abdelmotagly, Tina Gehring, Govindaraj N Rajkumar, Amr Emara, Richard G Hindley
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objectives:Rezum (Boston Scientific) water vapour therapy is an effective day case minimally invasive surgical treatment (MIST) for men with troublesome lower urinary tract symptoms (LUTSs) due to benign prostatic obstruction. The potential place for MISTs in the treatment of patients with urinary retention or permanent catheter dependence is currently unclear.Patients and Methods:A total of 48 patients presenting with retention of urine (out of a total of 524 patients) over a 4-year period from 2017 underwent Rezum treatment. All patients were followed up at 3, 6 and 12 months after the procedure. At each visit, flow rate, post void residual urine, and patient reported outcome measures (PROMs) including International Prostate Symptom Score (IPSS) were recorded.Results:A total of 34 patients had an indwelling catheter prior to treatment and 14 were self-catheterising. The mean age was 67 years (standard deviation (SD) = 3) with a mean prostate volume of 56 mL (SD = 6). The average number of injections per case was 8 (SD1), which included median lobe (ML) treatment in one man. 75% of the patients passed their post treatment trial without catheter (TWOC). IPSS improved to 6 (p = 0.001) in 12 months.Conclusion:The results from this cohort of patients are encouraging. Further evaluation with longer follow-up is required. The addition of MISTs to the portfolio of options for men with retention of urine may offer a streamlined and efficient alternative to the conventional treatments, and help therefore to reduce the national waiting list, and allow men a more rapid solution avoiding prolonged catheterisation.Level of evidence:Not applicable.
  Citation: Journal of Clinical Urology
  PubDate: 2024-02-29T11:55:59Z
  DOI: 10.1177/20514158241234390
Incidence of acute and delayed rectal toxicities following hydrogel spacer
insertion in men receiving dose-escalated radiotherapy for prostate cancer
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Prasanth Anton Sagayanathan, Ajanthan Loganathan, Ninan Tharakan, Arveen Kalapara, Stefan Antoniou, Luke McGhee, Simon Pridgeon
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objectives:The objective of this study was to evaluate the effectiveness of a hydrogel spacer in reducing acute and delayed rectal toxicities.Materials and Methods:Patients undergoing definitive radiotherapy between January 2015 and March 2018 were retrospectively identified from our institutional cancer registry. Planning data were collected on dose-volume histograms (DVH) for V65, V70 and V75 Gy. All patients underwent definitive volumetric modulated arc therapy (VMAT) of 78 Gy over 39 fractions in a single centre. Toxicity reporting and definitions were in accordance with Common Terminology Criteria for Adverse Events (CTCAE) guidelines.Results:A total of 162 patients received radiotherapy during the study period (spacer n = 80; no spacer n = 82). Baseline characteristics between groups were comparable. Acute rectal toxicity was documented in 19 men (24%) with spacer versus 36 men (44%) without spacer devices (p = 0.007). Over a median post-treatment follow-up period of 17 months (range = 3–38 months), there was a significant reduction in delayed toxicity in men with spacers compared to men without (17 men 21% vs. 31 men 39%, p = 0.021).Conclusion:Hydrogel spacer devices reduce rectal radiation exposure in prostate cancer patients undergoing radiotherapy. This translates into a clinical benefit in terms of acute and delayed rectal toxicities.Level of evidence:cohort study
  Citation: Journal of Clinical Urology
  PubDate: 2024-02-23T11:48:15Z
  DOI: 10.1177/20514158241229506
The efficacy of vardenafil and tamsulosin in treatment of lower urinary
tract symptoms secondary to benign prostatic hyperplasia: A randomised
clinical trial
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Mohamed Mahmoud Zaza, Adham Hussien Mohamed Hussien, Tarek Abdel-Majid Salem, Mohamed Hassan Ali Soliman
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objectives:This randomised controlled trial (RCT) aimed to evaluate the efficacy of vardenafil monotherapy, tamsulosin monotherapy, and combination therapy of vardenafil and tamsulosin in treating lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH).Methods:This RCT involved 75 patients presenting with LUTS secondary to BPH. Patients were randomly allocated into three groups, receiving either vardenafil monotherapy, tamsulosin monotherapy, or a combination of both drugs. Assessments and follow-ups were conducted 1, 3, and 6 months after treatment initiation, focusing on improvements in LUTS, uroflowmetry measurements, and patients’ sexual performance. Data analysis was performed using Microsoft Office Excel 2007 and IBM SPSS statistics software version 22.0.Results:This study included 75 participants divided into three groups. No significant differences were found in terms of patients’ age (p = 0.504) or treatment duration (p = 0.680) between the groups. The combination of vardenafil/tamsulosin consistently showed the lowest International Prostate Symptom Score (IPSS) scores and grades, followed by the tamsulosin group (p 0.001), but no significant differences were found between the tamsulosin and vardenafil/tamsulosin groups.Conclusion:The combination therapy with vardenafil and tamsulosin is more effective in improving LUTS secondary to BPH than monotherapy. Tamsulosin monotherapy also appears to be more effective than vardenafil monotherapy. Combination therapy provides a viable treatment option for patients who do not respond adequately to monotherapy or experience adverse effects from either drug.Level of Evidence:Moderate
  Citation: Journal of Clinical Urology
  PubDate: 2024-02-12T09:32:40Z
  DOI: 10.1177/20514158241227097
Does the drainage of irrigation through the ureteral access sheath have an
impact on the results of primary retrograde intrarenal surgery'
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Vaddi Chandramohan, PM Siddalinga Swamy, Paidakula Ramakrishna, Ganesan Soundarya, Manas Babu, Anandan Hemnath, Rakesh Panda
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Purpose:One of the risk factors associated with post-operative fever and infections is the amount of fluid absorbed by the kidney. We conducted a prospective study to analyse the effects of irrigation fluid inflow and outflow on post-operative complications and stone-free rate.Material and methods:We did a prospective study on all primary retrograde intrarenal surgery (RIRS) cases performed at our hospital between JAN 2020 and JAN 2023. The fluid draining out of the access sheath was collected in a measuring container until the flexible scope was inside the access sheath. The amount of fluid retained by the body was measured by calculating the difference between the quantity of irrigation fluid utilised and the output from the access sheath.Results:A total of 566 patients were included in the study. The retained volume of more than 100 ml was associated with more pain (0.0/426 vs 49/140, p
  Citation: Journal of Clinical Urology
  PubDate: 2024-02-03T12:34:39Z
  DOI: 10.1177/20514158241226550
Risk of isolated metastatic disease outside the abdomen is low in cT1a
renal cancer: A retrospective analysis of a large cohort from the Scottish
Renal Cancer Consortium
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Edward AA Mains, Sarika Nalagatla, Elizabeth McLellan, Alastair McKay, Matthew Trail, Daniel W Good, Jennifer B Ayers, Flora Rodger, James P Blackmur, Jane Hendry, Khaver Qureshi, Steve Leung, Simon Phipps, S Alan McNeill, Andrew Martindale, Khalid Janjua, James F Donaldson, Ben G Thomas, Alex Chapman, Grigorios Athanasiadis, Muhammad Zeeshan Aslam, Gavin Lamb, Grenville Oades, Alexander Laird
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objectives:Chest computed tomography (CT) is recommended by the European Association of Urology guidelines as part of the evaluation of patients presenting with renal tumours. There are no direct recommendations for the use of computed tomography (CT) pelvis, but this is often included routinely in the assessment for metastatic disease. The incidence of metastatic disease in cT1a renal cell carcinoma (RCC) is low. Predictive algorithms may be able to guide the selective use of chest CT in the pre-operative evaluation of patients. We sought primarily to assess the clinical utility of these algorithms in predicting lung and pelvic metastases in a national cohort of purely cT1a tumours.Patients and Methods:Patients with sporadic, unilateral cT1a renal tumours diagnosed between January 2012 and December 2017 were identified from a prospectively collected national database. Patient clinico-pathological parameters and treatment type were recorded. Details on clinical presentation and bloods at diagnosis were taken from local electronic records retrospectively. Differences between those with and without metastatic disease were assessed.Results:Of the total 696 patients, 7 (1.0%) patients had metastatic disease exclusively outside the abdomen. Indeterminate lung lesions were present in 114 (16.6%) patients, with 2 (1.8%) progressing to presumed metastatic disease. Patients with metastatic disease were more likely to be anaemic than those without metastatic disease (85.7% and 25.7%, respectively, p = 0.020).Conclusion:Metastatic disease at presentation with cT1a renal cancer was uncommon in our national multi-centre series, with limited impact on clinical management. Patients with cT1a without intra-abdominal metastatic disease could safely avoid CT chest or pelvic CT at diagnosis, with benefits in terms of radiation exposure and resource utilisation.Level of evidence:3.
  Citation: Journal of Clinical Urology
  PubDate: 2024-01-31T03:15:00Z
  DOI: 10.1177/20514158231223363
Investigating raised white cells, sepsis and antibiotic administration in
obstructive urolithiasis: A retrospective cohort analysis
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Deji Akiboye, Yan Leung, Muhesh Taheem, Stephen Gordon
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objectives:Patients with obstructive ureteric calculi frequently present with leucocytosis, prompting empirical antibiotic treatment. Evidence for antibiotics in these cases is limited. This study investigated whether leucocytosis is a reliable marker of sepsis in obstructive urolithiasis, and assessed factors associated with sepsis after emergency department (A&E) discharge, including antibiotic administration.Methods:Retrospective data collection was performed on all patients with computed tomography (CT)-proven ureteric calculi presenting to a single centre A&E between October 2019 and October 2020. Data were collected on patient demographics, comorbidities, stone factors, serum and urinalysis and relevant culture results. Multivariable regression analysis assessed significant correlations for immediate/delayed sepsis, serum leucocytes and antibiotic administration.Results:In total, 392 patients (298:98 M:F) met the inclusion criteria. Raised leucocytes were found in 212 patients (54.4%) with 24 patients (6.1%) admitted immediately with sepsis, and 12 (3.1%) returning with sepsis. In total, 83 patients received antibiotics, of whom 57 (68.7%) had no immediate or delayed sepsis. Multivariable regression showed immediate sepsis significantly associated with stone size, presence and degree of type 2 diabetes (p
  Citation: Journal of Clinical Urology
  PubDate: 2024-01-31T03:12:21Z
  DOI: 10.1177/20514158231221117
Trifecta rate and its predictor variables according to calibres in
percutaneous nephrolithotomy
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Juliusz Jan Szczesniewski, Juan Boronat Catalá, Alba María García-Cano, Percy Miguel Rodríguez Castro, Diego Torres Pérez, Luis Llanes González
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objective:The aim of this study is to determine and compare the number of patients who met the trifecta criteria using standard, Mini-15Fr and Ultra-Mini percutaneous nephrolithotomy (PCNL).Material and methods:Retrospective study of PCNL in Galdakao-modified supine Valdivia position with standard, Mini-15Fr and Ultra-Mini PCNL.Results:A total of 164 consecutive patients were analysed. Forty-six patients underwent standard PCNL (29.6%), 58 patients Mini-15Fr (34.4%) and 61 patients Ultra-Mini (36%). The Ultra-Mini had the lowest rate of complications (15%) followed by standard PCNL (18.6%) and Mini-15Fr (20.7%). There was no difference in stone-free rate (SFR). The trifecta rate was slightly higher in the Ultra-Mini at 65%, followed by the Mini-15Fr group (55%) and PCNL standard with 50% (p = 0.280). Univariate logistic regression found that lower surgical time (odds ratio (OR) = 1.01), tubeless technique (OR = 2.87) and shorter hospitalization (OR = 1.72) time were factors to favourable accomplishment of trifecta. In multivariate logistic regression, shorter hospitalization was established as independent predictor for achievement of trifecta (OR = 1.74).Conclusions:The miniaturized calibres in our study had a similar SFR and complications compared to the standard calibre in lithiasis smaller than 5 cm in diameter. The tubeless rate was higher and mean hospitalization was lower in the Mini-15Fr and Ultra-Mini. Tubeless technique and shorter hospitalization were predictors of trifecta.Level of evidence:2c
  Citation: Journal of Clinical Urology
  PubDate: 2024-01-30T09:35:02Z
  DOI: 10.1177/20514158241226859
Transitioning from a mobile to on-site extracorporeal shockwave
lithotripsy service: Is it worth it'
- Free pre-print version: Loading...
  Rate this result: What is this?
  
  Please help us test our new pre-print finding feature by giving the pre-print link a rating.
  A 5 star rating indicates the linked pre-print has the exact same content as the published article.
  
  Authors: Nour Abdel-Fattah, Sinan Khadhouri, Allan Johnston, Catriona Campbell, Jamie Krishnan, Laura Slater, Nicholas Cohen, Ismail Mokadem
  Abstract: Journal of Clinical Urology, Ahead of Print.
  Objectives:The aim of this study was to compare the efficiency and effectiveness of a previous mobile versus current on-site lithotripsy service at a tertiary referral centre.Methods:Patient demographics, stone properties and service provision data were collected; retrospectively for mobile extracorporeal shockwave lithotripsy service (mESWL) between December 2017 and December 2018, and prospectively for on-site extracorporeal shockwave lithotripsy service (osESWL) between March 2019 and March 2020.Results:The overall stone clearance rate for mESWL was 57.1% (68/119) and 79.2% (164/207) for osESWL (p
  Citation: Journal of Clinical Urology
  PubDate: 2024-01-12T01:07:09Z
  DOI: 10.1177/20514158231222062

HOME > Browse the 73 Subjects covered by JournalTOCs
Subject	Total Journals