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Clinical Nephrology
Journal Prestige (SJR): 0.535  Citation Impact (citeScore): 1 Number of Followers: 6  Subscription journalISSN (Print) 0301-0430 Published by Dustri-Verlag  [2 journals]
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- Spontaneous remission of de novo membranous nephropathy in post-allogeneic
hematopoietic stem cell transplantation patients: A report of two cases-
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Authors: Wai Lun Will Pak, Ann Jakubowski, Miguel-Angel Perales, Claudia Michelle Brauer Obrador, Steven Salvatore, Surya Seshan, Ilya Glezerman
Abstract: Membranous nephropathy (MN) is one of the most common de novo glomerular diseases developing in patients after allogeneic hematopoietic stem cell transplantation (HSCT). Most authors have used immunosuppression for its treatment to target the underlying immune-mediated processes, akin to graft-versus-host disease, but the optimal management is currently unclear. Limited reports in the literature described the use of a conservative approach with success, particularly in cases with lower risks of...
Citation: Clinical nephrology
PubDate: 2024-08-19
DOI: 10.5414/CN111431
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- Kidney transplantation in multiple myeloma in 2023: A short review
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Authors: Gonçalo Ávila, Marisa Roldão, Hugo Ferreira, Inês Coelho, Teresa Chuva, Ana Paiva, José Maximino Costa
Abstract: Patients with multiple myeloma (MM) frequently present with kidney involvement, of which a non-negligible proportion will progress to end-stage kidney disease. Kidney transplantation (KT) is the preferred kidney replacement therapy for selected patients; however, there are still many uncertainties regarding its application in MM patients. The risk of hematological relapse and subsequent graft loss or patient death often leads nephrologists to deem these patients unfit for KT. As such, data on KT...
Citation: Clinical nephrology
PubDate: 2024-08-19
DOI: 10.5414/CN111241
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- Current use, training, and barriers in point-of-care ultrasound in
nephrology: A national survey of VA medical centers-
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Authors: Kevin J Murray, Abhilash Koratala, Ariadna Perez-Sanchez, Terry Lund, Anthony Andrade, Steven M Gorbatkin, John M Duch, Sandipani Sandilya, Jorge Lamarche, Michael J Mader, Elizabeth K Haro, Nilam J Soni, Robert Nathanson
Abstract: CONCLUSION: A minority of nephrology groups currently use common POCUS applications including evaluation of urinary retention, hydronephrosis, and volume status. The most common barriers to POCUS use in nephrology were lack of trained providers and ultrasound equipment. Investment in POCUS training and infrastructure is needed to expand and standardize POCUS use in nephrology.
Citation: Clinical nephrology
PubDate: 2024-08-09
DOI: 10.5414/CN111464
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- Idiopathic nodular glomerulosclerosis: A case report and literature review
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Authors: Huan Yang, Ying Li, Zhenkun He, Yunjuan Liao, Chunrui Yang, ShanShan Dong
Abstract: This paper reports a 49-year-old male patient with a long-term smoking history who developed renal insufficiency and proteinuria in the range of nephropathy without diabetes. Renal biopsy showed nodular glomerulosclerosis with vitreous degeneration of arterioles and moderate and severe proliferation of glomerular mesangial cells and matrix. The patient was diagnosed with idiopathic nodular glomerulosclerosis. After treatment with angiotensin-converting enzyme inhibitor/angiotensin II receptor...
Citation: Clinical nephrology
PubDate: 2024-08-09
DOI: 10.5414/CN111382
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- Kidney complications of Wilson disease and its treatments: A case report
and literature review-
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Authors: Maria Salman, Ayub Akbari, Gregory L Hundemer
Abstract: Wilson disease is a rare autosomal recessive genetic disorder of copper metabolism that leads to copper accumulation and subsequent organ dysfunction. While classically considered a condition that primarily affects the liver and nervous system, Wilson disease and its treatments can also result in a wide range of kidney complications as well. We present the case of a 31-year-old female with a longstanding (> 10 year) history of Wilson disease who developed acute-onset nephrotic syndrome including...
Citation: Clinical nephrology
PubDate: 2024-08-05
DOI: 10.5414/CN111402
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- Clinicopathological features and outcomes of PLA2R-related membranous
nephropathy with renal glycosuria-
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Authors: Piao Zhang, Feng Xu, Xumeng Liu, Ziyun Hu, Dandan Liang, Shaoshan Liang, Xiaodong Zhu, Fan Yang, Caihong Zeng
Abstract: CONCLUSION: PLA2R-related MN patients with renal glycosuria presented with more severe clinicopathological manifestations and worse prognoses. Nephrotoxic drugs should be administered rationally, and RTX should be considered as a promising treatment option.
Citation: Clinical nephrology
PubDate: 2024-08-05
DOI: 10.5414/CN111362
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- Post-COVID-19 complement-mediated TMA: A case report
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Authors: Jan A Jochims, Babak Yazdani, Bernd Krüger, Zoran V Popovic, Bernhard K Krämer
Abstract: Systemic COVID-19 disease is associated with a variety of organ involvement in infected patients. A rarely reported complication is the induction of complement-mediated thrombotic microangiopathy (TMA). TMA is an extremely rare pathological condition that results in thrombosis in capillaries and small arterioles, due to an endothelial injury. It is often combined with thrombocytopenia, Coombs-negative hemolytic anemia, and end-organ damage. This case involves a patient who was admitted to our...
Citation: Clinical nephrology
PubDate: 2024-07-24
DOI: 10.5414/CN111217
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- Immunosuppressant-resistant nephrotic syndrome and primary amenorrhea: A
case report of adult Frasier syndrome and literature review-
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Authors: Caifeng Li, Liyu Lin, Tao Pu, Jie Teng, Ziyan Shen
Abstract: We present a case of a 19-year-old who developed nephrotic syndrome with preserved renal function. Renal biopsy confirmed focal segmental glomerular sclerosis (FSGS). No remission was achieved despite 2 years of treatment with glucocorticoids, mycophenolate mofetil, tacrolimus, and cyclophosphamide. After transfer to our center, we performed re-examination of renal pathology by electron microscope (EM), chromosomal karyotype, and gene analysis. EM revealed uneven thickness of the glomerular...
Citation: Clinical nephrology
PubDate: 2024-07-22
DOI: 10.5414/CN111432
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- Risk factors for in-hospital mortality among patients hospitalized with
COVID-19 and end-stage kidney disease-
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Authors: Jackson Heilbronn, Amir Abdipour, Giv Heidari-Bateni, Mohammad Sharif, Sahib Grewal, Sergio Infante, Kwame Agyeman, Zohreh Gholizadeh Ghozloujeh, Lida Gharibvand, Sayna Norouzi
Abstract: CONCLUSION: Cardiovascular disease is the leading cause of mortality for ESKD patients and also places them at increased risk of mortality in the setting of severe COVID-19 infection.
Citation: Clinical nephrology
PubDate: 2024-07-22
DOI: 10.5414/CN111323
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- The efficacy of sacubitril/valsartan in patients receiving peritoneal
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Authors: Xueyan Bian, Jianwei Ma, Qin Su, Qiang Yu, Jiancheng Huang, Sizeng Bao, Ji Ying
Abstract: CONCLUSION: The findings suggest that sacubitril/valsartan can safely and effectively improve RRF and cardiac function in patients with diabetes combined with HFpEF receiving PD, but it has little effect on PD adequacy.
Citation: Clinical nephrology
PubDate: 2024-07-22
DOI: 10.5414/CN111320
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- Biopsy-proven BK virus nephropathy in renal transplant recipients:
A -multi-central study from Turkey (BK-TURK STUDY)-
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Authors: Ozkan Gungor, Hamad Dheir, Mahmud Islam, Huseyin Toz, Abdulmecit Yildiz, Ayse Sinangil, Erhan Tatar, Gulay Asci, Ozkan Ulutas, Eda Altun, Orcun Altunoren, Suheyla Apaydin, Alparslan Ersoy, Berfu Korucu, Seda Safak, Ulver Derici, Saliha Yildirim, Nurhan Seyahi, Seyda Gul Ozcan, Kadir Gokhan Atilgan, Mehmet Deniz Ayli, Caner Cavdar, Ozcan Uzun, Rahmi Yilmaz, Arda Erdut, Mustafa Sevinc, Umut Kasapoğlu, Ismail Kocyigit, Cihan Uysal, Kultigin Turkmen, Hakan Ozer, Arzu Velioglu, Ebru Ok, Bulent Kaya, Zulfikar Yilmaz, Oktay Ozkan, Egemen Cebeci, Kenan Turgutalp, Meltem Gursu, Enver Yuksel, Necmi Eren, Erkan Dervisoglu, Fatma Betul Guzel, Gursel Yildiz, Serkan Bakirdogen, Ayca Inci, Can Sevinc, Aydin Turkmen
Abstract: CONCLUSION: BKVN is still a frequent cause of allograft loss in kidney transplantation and is not fully elucidated. The results of our study suggest that leflunomide treatment is associated with more favorable allograft outcomes.
Citation: Clinical nephrology
PubDate: 2024-07-22
DOI: 10.5414/CN111300
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- Fibrillary glomerulonephritis in a patient with rheumatoid arthritis:
A case report and review of the literature-
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Authors: Olivia Schreiber, Michael Chau, Solomon Dawson, Vinay Srinivasan
Abstract: Fibrillary glomerulonephritis (FGN) is a rare glomerular disease defined by the presence of microfibrils that deposit within the glomeruli. While initially thought to be idiopathic, FGN is now recognized to be associated with infection, malignancies, and autoimmune disorders. We describe a case of biopsy-proven FGN in a patient with seropositive rheumatoid arthritis (RA) and provide a review of the literature regarding the association of FGN with RA.
Citation: Clinical nephrology
PubDate: 2024-07-22
DOI: 10.5414/CN111259
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- Comment to "Familial polycystic kidneys with no genetic confirmation: Are
we sure it is ADPKD'". Clin Nephrol. 2023; 99: 149 - 152-
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Authors: Liliana Italia De Rosa, Giulia Mancassola, Maria Teresa Sciarrone Alibrandi
Abstract: No abstract
Citation: Clinical nephrology
PubDate: 2024-07-12
DOI: 10.5414/CN111418
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- Denosumab for immobilization-induced hypercalcemia in patients with
end-stage renal disease-
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Authors: Jugal Thaker, Abdallah S Geara
Abstract: No abstract
Citation: Clinical nephrology
PubDate: 2024-07-12
DOI: 10.5414/CN111361
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- Influenza vaccination-associated cryoglobulinemic vasculitis
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Authors: Estelle Taki, Stephanie Wirtshafter, Abdallah S Geara
Abstract: Mixed cryoglobulinemia is a small vessel vasculitis associated with viral infections, mainly hepatitis C virus, however, other important causes include lymphoproliferative and autoimmune disorders. Influenza vaccine-induced cryoglobulinemia has been rarely reported. A 68-year-old male presented on three occasions following influenza vaccination with purpuric rash and lower extremities swelling. His lab work showed mixed cryoglobulins. On his most recent presentation, in addition to the purpura,...
Citation: Clinical nephrology
PubDate: 2024-07-12
DOI: 10.5414/CN111383
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- Association of vitamin intake with health-related quality of life in
hemodialysis patients-
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Authors: Ursula Alchabab, Razane El Hajj Chehade, Chloe Kharsa, Rebecca Kassab, Serena Maria Dib, Dania Chelala, Jenny Hawi, Celine Boueri, Hiba Azar, Serge Finianos, Ibrahim Abdo, Chadia Beaini, Mabel Aoun
Abstract: CONCLUSION: A higher number of vitamins in hemodialysis patients is associated with an increased perception of the burden of kidney disease. Interventional studies are needed to assess whether selective vitamin supplementation in case of deficiencies is associated with better quality of life.
Citation: Clinical nephrology
PubDate: 2024-07-12
DOI: 10.5414/CN111306
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- Efficacy of urokinase in maintaining patency of hemodialysis catheters:
A meta-analysis-
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Authors: Jiaxiu Deng, Weixiang Luo, Weiwei Zhang, Shiyi Xiong, Liping Wang
Abstract: CONCLUSION: Urokinase locking maintains catheter patency more effectively than heparin. Prophylactic locking with urokinase or urokinase mixtures reduces incidences of catheter malfunction, which ensures the smooth progression of hemodialysis and reduces patient medical costs. The results of this study have important clinical implications and will provide guidance to medical practitioners globally.
Citation: Clinical nephrology
PubDate: 2024-07-12
DOI: 10.5414/CN111239
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- Efficacy and safety analysis of sodium zirconium cyclosilicate and calcium
polystyrene sulfonate on rapid reduction of potassium in moderate to
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Authors: XiaoJuan Fu, Sen Zhang, Fang Gao, Nan Mao
Abstract: CONCLUSION: Sodium zirconium cyclosilicate has a more obvious effect on reducing potassium particularly for those patients with moderate to severe hyperkalemia who need rapid potassium reduction.
Citation: Clinical nephrology
PubDate: 2024-07-12
DOI: 10.5414/CN111226
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- Analysis of IgG subclass staining for IgG immunofluorescence-positive
IgA nephropathy-
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Authors: Hideyo Oguchi, Yui Nakayama, Naobumi Tochigi, Tetuo Mikami, Noriyuki Kounoue, Junya Hashimoto, Yuko Hamasaki, Ken Sakai
Abstract: CONCLUSION: IgG1-positive IF staining intensity was highest among each IgG subclass in IgG IF-positive IgAN biopsies. A negative correlation was revealed between the age at biopsy and IgG1 IF intensity. Oxford E and C scores were higher in patients with IgG IF-positive IgAN than in those with IgG IF-negative IgAN. The Oxford score was not significantly different between the IgG subclasses, but the IF intensity of IgG had a positive correlation with the IF intensity of IgG1 in IgG IF-positive...
Citation: Clinical nephrology
PubDate: 2024-07-02
DOI: 10.5414/CN111352
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- Combining telemedicine and in-person visits to deliver care to patients
with severe chronic kidney disease (CKD): Lessons learned from COVID-19-
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Authors: Gaetano Alfano, Silvia Cazzato, Laura Diotallevi, Francesco Giaroni, Francesco Fontana, Silvia Giovanella, Giulia Ligabue, Giacomo Mori, Elena Santini, Paola Dondi, Patrizia Palumbo, Rossella Giannini, Renata Menozzi, Annachiara Ferrari, Mariacristina Gregorini, Gianni Cappelli, Riccardo Magistroni, Gabriele Donati
Abstract: CONCLUSION: Telemedicine made it possible to provide care to and maintain close monitoring of 2/3 of patients with pre-dialytic stage of CKD during the COVID-19 pandemic.
Citation: Clinical nephrology
PubDate: 2024-07-02
DOI: 10.5414/CN111141
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- Clinical management of unremitting nephrogenic diabetes insipidus
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Authors: Nasha Elavia, Matthew R Weir, Abdolreza Haririan, Sarah H Khan
Abstract: The polyuria and polydipsia state in diabetes insipidus (DI) can be challenging to manage for patients and clinicians with significant impact on the patients' well-being. A review of literature shows that nonsteroidal anti-inflammatory drugs (NSAIDs), thiazide and potassium-sparing diuretics, along with low dietary solute and protein, and high water intake remain the standard medical therapy. Although these therapeutic approaches improve symptoms, the urine-concentrating defect is still...
Citation: Clinical nephrology
PubDate: 2024-06-25
DOI: 10.5414/CN111366
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- The influence of gut microbiota on membranous nephropathy: A two-sample
Mendelian randomization study-
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Authors: Qian Wu, Tingting Zheng, Sheng Xie, Jue Zhu, Ling Yuan, Wei Wei, Na Lyu
Abstract: CONCLUSION: Our findings provided causal evidence for the effect of gut microbiota on MN patients and broadened the spectrum of bacterial taxa that might be involved in the pathogenesis of MN. These selected bacterial taxa hold promise as new biomarkers, which may aid in designing targeted therapeutic modalities for MN, improving our comprehension of the gut-kidney axis.
Citation: Clinical nephrology
PubDate: 2024-06-25
DOI: 10.5414/CN111346
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- Metabolic acidosis and sexual dysfunction in chronic kidney disease in
predialysis group: Cross-sectional study from a single center-
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Authors: Elif Ilhan, Sibel G Bek, Irem Sarıoglu, Sibel Balcı, Ozge Tekdemir, Metin Ergül, Erkan Dervisoglu, Betul Kalender
Abstract: CONCLUSION: Metabolic acidosis and low eGFR appear to be the most important risk factors contributing to sexual disorders in patients with CKD.
Citation: Clinical nephrology
PubDate: 2024-06-11
DOI: 10.5414/CN111396
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- Decreased IgA binding levels were accompanied by increased IgG sialylation
in IgA nephropathy-
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Authors: Youxia Liu, Hongshan Chen, Hongfen Li, Fanghao Wang, Yue Xing, Zhanfei Wu, Wenying Li, Junya Jia, Tiekun Yan
Abstract: CONCLUSION: The preliminary findings from our present study indicate that the binding level of IgA in purified sialylated IgG is lower than that in desialylated IgG.
Citation: Clinical nephrology
PubDate: 2024-06-10
DOI: 10.5414/CN111406
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- Hypercalcemia of malignancy: Cancer treatment can be a cause as well
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Authors: Hassan Izzedine, Rose Mary Attieh, Farhana Begum, Yee-Ming Melody Cheung, Kenar D Jhaveri
Abstract: While the incidence of hypercalcemia of malignancy (HCM) is on the decline, it still occurs in up to 30% of patients with cancer. Immune checkpoint inhibitor (ICI)-related hypercalcemia is becoming increasingly recognized. We describe a case of cemiplimab-induced hypercalcemia in a patient with metastatic squamous cell carcinoma of the earlobe and discuss a management algorithm for HCM. Timely diagnosis and management of HCM is critical for optimal care and the prevention of complications.
Citation: Clinical nephrology
PubDate: 2024-06-07
DOI: 10.5414/CN111403
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- Sagliker syndrome in a patient with end-stage renal disease and
uncontrolled secondary hyperparathyroidism-
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Authors: Yuefang Ru, Lingjie Xue, Min-Gang Zhu, Xiaolan Ye, Er-Min Gu
Abstract: No abstract
Citation: Clinical nephrology
PubDate: 2024-06-05
DOI: 10.5414/CN111327
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- Phosphorus: Chronicles of the epistemology of a vital element
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Authors: Garabed Eknoyan, Eleanor D Lederer
Abstract: It was in the philosopher's stone quest that the alchemist Hennig Brand isolated chemiluminescent white phosphorus (P), Greek for "light bearer", from urine in 1669. By 1771 phosphorus was isolated from bone, and in 1777 it was identified by Antoine Lavoisier as a highly reactive element that exists predominantly in nature as ionic phosphate (PO(4)^(3-)) and in solution as phosphoric acid (H(3)PO(4)). Early 20^(th) century studies revealed phosphorylated biomolecules as essential components of...
Citation: Clinical nephrology
PubDate: 2024-06-05
DOI: 10.5414/CN111435
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- IgG4-associated disease with systemic lupus erythematosus: A case report
and review-
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Authors: Ruyi Xie, Huimin Li, Xian Wang, Xiaowei Li
Abstract: We report a 67-year-old man who presented with poor dietary intake and fatigue. Laboratory tests showed leukopenia, antinuclear antibody (ANA) positivity, anti-dsDNA antibody (A-dsDNA) and anti-Smith antibody (anti-Sm) negativity, decreased C3 and C4, elevated serum immunoglobulin G (IgG), IgG4, and creatinine, and 1.25 g urinary protein at 24 hours. As his condition worsened, re-examination showed thrombocytopenia and A-dsDNA positivity, and renal biopsy pathology showed IgG4-related...
Citation: Clinical nephrology
PubDate: 2024-06-05
DOI: 10.5414/CN111343
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- Membranous-like glomerulopathy with masked monotypic IgG deposits:
A single center case series-
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Authors: Rosemary Attieh, Kumail Merchant, Yihe Yang, Christine Sethna, Kenar D Jhaveri
Abstract: CONCLUSION: MGMID can affect both adult and pediatric patients. Further studies are needed to fully characterize its risk factors, optimal therapy, and outcomes.
Citation: Clinical nephrology
PubDate: 2024-06-05
DOI: 10.5414/CN111305
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- Mind the gap in kidney care: Translating what we know into what we do
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Authors: Valerie A Luyckx, Katherine R Tuttle, Dina Abdellatif, Ricardo Correa-Rotter, Winston W S Fung, Agnès Haris, Li-Li Hsiao, Makram Khalife, Latha A Kumaraswami, Fiona Loud, Vasundhara Raghavan, Stefanos Roumeliotis, Marianella Sierra, Ifeoma Ulasi, Bill Wang, Siu-Fai Lui, Vassilios Liakopoulos, Alessandro Balducci
Abstract: Historically, it takes an average of 17 years to move new treatments from clinical evidence to daily practice. Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long. The time is now to narrow the gap between what we know and what we do. Clear guidelines exist for the prevention and management of common risk factors for kidney disease, such as hypertension and diabetes, but only a fraction of people with these conditions...
Citation: Clinical nephrology
PubDate: 2024-05-31
DOI: 10.5414/CNWKDEdi24
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- First episode of febrile urinary tract infection in children, detection
and risk factors of kidney scarring: A prospective cohort study-
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Authors: Despoina Tramma, Vaia Dokousli, Despoina Samourkasidou, Nikolaos Gkiourtzis
Abstract: CONCLUSION: VUR did not appear to be associated with the first episode of APN, and children older than 1 year of age had a higher risk of scarring. Antibiotic prophylaxis may prevent kidney scarring due to host immunomodulatory effects, but more studies are needed so that conclusions can be drawn.
Citation: Clinical nephrology
PubDate: 2024-05-10
DOI: 10.5414/CN111307
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- Variable phenotype and genotype of pediatric patients with HNF1B
nephropathy-
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Authors: Bora Gülhan, Ozan Ekici, İsmail Dursun, Nilüfer Göknar, Selçuk Yüksel, Demet Alaygut, Zeynep Birsin Özçakar, Hülya Nalçacıoğlu, Beltinge Demircioğlu Kılıç, Oğuz Söylemezoğlu, Ali Duzova, Rezan Topaloglu, Fatih Ozaltin
Abstract: CONCLUSION: Patients with HNF1B-associated disease have concomitant urinary system abnormalities such as VUR or UPJO. Missense variants seem to be the most common pathological variations in HNF1B gene and have higher risk of CKD.
Citation: Clinical nephrology
PubDate: 2024-05-03
DOI: 10.5414/CN111310
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- Spectrum of renal disease in scleroderma other than scleroderma renal
crisis: A review of the literature-
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Authors: Larabe Farrukh, Virginia Steen, Lee Shapiro, Geovani Faddoul, Swati Mehta
Abstract: CONCLUSION: The spectrum of kidney involvement in SSc can range from asymptomatic reduction of the glomerular filtration rate to life-threatening scleroderma renal crisis. Therefore, it is essential that physicians closely monitor renal function in these patients for any emerging renal dysfunction.
Citation: Clinical nephrology
PubDate: 2024-05-03
DOI: 10.5414/CN111243
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- Shorter observation times and smaller gauge needles in outpatient kidney
biopsies-
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Authors: Larab L Giniyani, James McGee, Maria V DeVita, Revana T Rahman, Andrew A Moses, Jordan L Rosenstock
Abstract: Controversy exists as to the optimal observational time (OT) after outpatient percutaneous kidney biopsy. Further, there is some uncertainty about the benefit of smaller (18-gauge) vs. larger (16-gauge) biopsy needles. At our institution, we have been lowering the OT after outpatient kidney biopsies. Initially in 2015, we were monitoring for 6 hours and gradually began to decrease the OT over time. From 2020, we have adopted an OT of less than 4 hours. During this time period (in 2018), we also...
Citation: Clinical nephrology
PubDate: 2024-05-03
DOI: 10.5414/CN111132
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- A comparative analysis of kidney allograft outcomes in steroid use versus
steroid discontinuation after basiliximab and ATG induction: A UNOS
database study-
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Authors: Pitchaphon Nissaisorakarn, Het Patel, Francesca Cardarelli, Aala Amtul
Abstract: CONCLUSION: Patients who were maintained on steroids after basiliximab induction had better 5-year allograft survival and patient survival compared to those who were not maintained on steroids. However, steroid maintenance conferred no additional benefit after ATG induction and was associated with higher mortality.
Citation: Clinical nephrology
PubDate: 2024-05-03
DOI: 10.5414/CN111033
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- Incorporating genetic testing into a routine kidney clinic
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Authors: Jingjing Zhang, Wing Zeng, Seyed Hamrahian, Omar H Maarouf
Abstract: Incorporating genetic testing in routine outpatient nephrology clinic can improve on chronic kidney disease (CKD) diagnosis and utilization of precision medicine. We sent a genetic test on patients with atypical presentation of common kidney diseases, electrolytes derangements, and cystic kidney diseases. We were able to identify a gene variant contributing to patients' kidney disease in more than half of our cohort. We then showed that patients with ApoL1 risk allele have likely worse kidney...
Citation: Clinical nephrology
PubDate: 2024-04-25
DOI: 10.5414/CN111138
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- Rituximab treatment in resistant lupus nephritis: A single-center
prospective study-
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Authors: Shahzad Alam, Mastakim Ahmed Mazumder, Manjuri Sharma, Pranab Jyoti Mahanta, Manzoor Ahmand Parry, Prodip Kumar Doley
Abstract: CONCLUSION: Rituximab is a safe and effective therapeutic strategy for patients with resistant LN.
Citation: Clinical nephrology
PubDate: 2024-04-25
DOI: 10.5414/CN111104
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- Physical functional capacity assessment in children with chronic kidney
disease: A cross sectional observational study-
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Authors: Himani Goswami, Harda Shah, Kinnari Vala, Shahenaz Kapadia, Bharat Tiwari, Anshuman Saha
Abstract: CONCLUSION: Muscle strength and functional capacity were most impaired in Indian children on hemodialysis and best preserved in KTR.
Citation: Clinical nephrology
PubDate: 2024-04-17
DOI: 10.5414/CN111295
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- Application of improved glomerular filtration rate estimation by a neural
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Authors: Ying-Chun Ma, Yang Xie, Limin Liao
Abstract: CONCLUSION: The MLP-based model offered significant advantages in estimating GFR in Chinese NLUTD patients, and its application could be suggested in clinical practice.
Citation: Clinical nephrology
PubDate: 2024-04-17
DOI: 10.5414/CN111150
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- Effect of cyclophosphamide combined with glucocorticoid therapy on
idiopathic membranous nephropathy: A multicenter open-label randomized
controlled trial-
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Authors: Jianlin Wang, Dong Bian, Jian Sun
Abstract: CONCLUSION: Cyclophosphamide combined with glucocorticoid therapy is effective for improving the overall remission rate and can suppress inflammatory responses and oxidative stress in patients with idiopathic membranous nephropathy.
Citation: Clinical nephrology
PubDate: 2024-04-12
DOI: 10.5414/CN111287
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- Evaluating prescription of angiotensin-converting enzyme inhibitors or
angiotensin II receptor blockers in patients with diabetes and albuminuria
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Authors: Kittiphan Chienwichai, Phirada Chaloemwa, Sorawat Sangkaew, Arunchai Chang
Abstract: CONCLUSION: ACEi/ARB therapy was suboptimal in patients with diabetes, hypertension, and albuminuria. Non-adherence was associated with CKD stage, possibly because of concerns about adverse events and healthcare-related factors.
Citation: Clinical nephrology
PubDate: 2024-04-12
DOI: 10.5414/CN111247
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- Tolvaptan therapy for edema in patients with chronic kidney disease
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Authors: Li Zhou, Qianqian Xu, Xuehua Xi, Xueying Yu, Wenge Li
Abstract: CONCLUSION: As long as a rational treatment regimen is followed, tolvaptan is a safe and effective diuretic for treating edema in CKD, even in the late stages of CKD without reducing residual renal function in the patients.
Citation: Clinical nephrology
PubDate: 2024-04-05
DOI: 10.5414/CN111365
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- Acute kidney injury in children with lymphoma
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Authors: Hejia Zhang, Yanlong Duan, Xiaoxue Li, Zhi Chen, Xiaorong Liu
Abstract: CONCLUSION: TLS, lung infection, and lymphoma clinical stage were identified as independent risk factors for AKI in children with lymphoma during the first 30 days of hospitalization. Clinicians should increase their awareness of AKI in hospitalized patients with lymphoma.
Citation: Clinical nephrology
PubDate: 2024-03-26
DOI: 10.5414/CN111157
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- The diversity of peripheral blood T cells and myeloid-derived suppressor
cells in patients with idiopathic membranous nephropathy-
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Authors: Xiaohu Shi, Mingqiang Zhang, Gangan Wang, Gang Chen, Rongrong Hu, Xuewang Lee, Xuemei Li
Abstract: CONCLUSION: Tregs and G-MDSCs were reduced in the circulation of the IMN patients, which may promote understanding of the crucial functions that are mediated by these cells in the pathogenesis of IMN.
Citation: Clinical nephrology
PubDate: 2024-03-21
DOI: 10.5414/CN111059
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- SARS-CoV-2 Omicron infection in a cohort of hospitalized kidney
transplant recipients: Risk factors of severity-
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Authors: Zhitao Cai, Tianyu Wang
Abstract: CONCLUSION: Renal transplant recipients were generally susceptible to infection with the Omicron variant, with a more pronounced incidence of severe illness observed in the group with hypertension comorbidity.
Citation: Clinical nephrology
PubDate: 2024-03-18
DOI: 10.5414/CN111303
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- Incidence and risk factors of acute kidney injury after transcatheter
aortic valve replacement-
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Authors: Zhenjian Xu, Xin Zhou, Hui Yang, Qiuju Chen, Guangxuan Luo, Shichun Cai, Anping Xu
Abstract: CONCLUSION: A retrospective study revealed a 17.3% incidence of AKI after TAVR surgery in our hospital, most of which were stage 1 AKI. A low preoperative eGFR and contrast volume were found to be independent risk factors for AKI.
Citation: Clinical nephrology
PubDate: 2024-03-18
DOI: 10.5414/CN111269
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- Implication of acute tubular injury in minimal change nephrotic syndrome
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Authors: Hillary Grainer, Maria V DeVita, Tung Ming Leung, Vanesa Bijol, Jordan L Rosenstock
Abstract: While acute tubular injury (ATI) is known to occur in a significant number of minimal change disease (MCD) nephrotic syndrome cases with acute kidney injury (AKI), the clinical significance is not certain, and AKI may also occur without ATI. This study aimed to evaluate whether the severity of AKI defined by Kidney Disease Improving Global Outcomes (KDIGO) criteria correlated with the presence or severity of ATI in a series of adult patients with MCD. We also looked at whether time to remission...
Citation: Clinical nephrology
PubDate: 2024-03-18
DOI: 10.5414/CN111218
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- Characteristics of neutralizing antibody titers of the SARS-CoV-2 vaccine
in maintenance hemodialysis patients-
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Authors: Yoshifumi Amari, Satoshi Morimoto, Takashi Teranishi, Yu Motoike, Takatomi Yurugi, Yasuo Oyama, Fumitaka Nakajima, Hitoshi Kobayashi
Abstract: CONCLUSION: This study confirmed that patients undergoing hemodialysis were proven to have acquired sufficient antibody titers after the vaccination.
Citation: Clinical nephrology
PubDate: 2024-03-18
DOI: 10.5414/CN111179
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- The role of complement inhibitors in thrombotic microangiopathy with
systemic lupus erythematosus-
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Authors: Aliza Anwar Memon, Krista L Lentine, David Brink, Mowaffaq Said
Abstract: No abstract
Citation: Clinical nephrology
PubDate: 2024-03-03
DOI: 10.5414/CN111279
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- Determinants of non-diabetic kidney diseases in type 2 diabetic patients:
Twenty years of single center experience-
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Authors: Tamer Sakaci, Elbis Ahbap, Taner Basturk, Mustafa Ortaboz, Ayse Aysim Ozagari, Emrah Erkan Mazı, Kamile Gulcin Eken, Nuri Baris Hasbal, Abdulkadir Unsal
Abstract: CONCLUSION: Renal biopsy findings in patients with type 2 DM highlight that the prevalence of NDN may be higher than assumed, as presented mainly in the form of primary glomerular disease. The presence of AKI/RPKD, hematuria, and ANS/ANP serves as a reliable indicator of non-diabetic renal pathology. In more ambiguous situations, factors such as a shorter duration of diabetes, absence of DRP, and a lower NLR value may assist clinicians in biopsy decision.
Citation: Clinical nephrology
PubDate: 2024-03-03
DOI: 10.5414/CN111093
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