Subjects -> MEDICAL SCIENCES (Total: 8196 journals)
    - ALLERGOLOGY AND IMMUNOLOGY (205 journals)
    - ANAESTHESIOLOGY (105 journals)
    - CARDIOVASCULAR DISEASES (334 journals)
    - CHIROPRACTIC, HOMEOPATHY, OSTEOPATHY (19 journals)
    - COMMUNICABLE DISEASES, EPIDEMIOLOGY (227 journals)
    - DENTISTRY (266 journals)
    - DERMATOLOGY AND VENEREOLOGY (162 journals)
    - EMERGENCY AND INTENSIVE CRITICAL CARE (121 journals)
    - ENDOCRINOLOGY (149 journals)
    - FORENSIC SCIENCES (43 journals)
    - GASTROENTEROLOGY AND HEPATOLOGY (178 journals)
    - GERONTOLOGY AND GERIATRICS (125 journals)
    - HEMATOLOGY (160 journals)
    - HYPNOSIS (4 journals)
    - INTERNAL MEDICINE (177 journals)
    - LABORATORY AND EXPERIMENTAL MEDICINE (90 journals)
    - MEDICAL GENETICS (58 journals)
    - MEDICAL SCIENCES (2241 journals)
    - NURSES AND NURSING (331 journals)
    - OBSTETRICS AND GYNECOLOGY (199 journals)
    - ONCOLOGY (355 journals)
    - OPHTHALMOLOGY AND OPTOMETRY (135 journals)
    - ORTHOPEDICS AND TRAUMATOLOGY (150 journals)
    - OTORHINOLARYNGOLOGY (76 journals)
    - PATHOLOGY (96 journals)
    - PEDIATRICS (254 journals)
    - PHYSICAL MEDICINE AND REHABILITATION (153 journals)
    - PSYCHIATRY AND NEUROLOGY (800 journals)
    - RADIOLOGY AND NUCLEAR MEDICINE (182 journals)
    - RESPIRATORY DISEASES (109 journals)
    - RHEUMATOLOGY (76 journals)
    - SPORTS MEDICINE (77 journals)
    - SURGERY (388 journals)
    - UROLOGY, NEPHROLOGY AND ANDROLOGY (151 journals)

UROLOGY, NEPHROLOGY AND ANDROLOGY (151 journals)                     

Showing 1 - 144 of 144 Journals sorted alphabetically
Actas Urológicas Españolas     Full-text available via subscription   (Followers: 1)
Actas Urológicas Españolas (English Edition)     Full-text available via subscription   (Followers: 1)
Advances in Chronic Kidney Disease     Hybrid Journal   (Followers: 15)
Advances in Urology     Open Access   (Followers: 13)
African Journal of Nephrology     Open Access   (Followers: 1)
African Journal of Urology     Open Access   (Followers: 7)
AJP Renal Physiology     Hybrid Journal   (Followers: 8)
Aktuelle Urologie     Hybrid Journal   (Followers: 4)
American Journal of Kidney Diseases     Hybrid Journal   (Followers: 53)
American Journal of Men's Health     Open Access   (Followers: 9)
American Journal of Nephrology     Full-text available via subscription   (Followers: 31)
Andrologia     Hybrid Journal   (Followers: 3)
Andrology     Hybrid Journal   (Followers: 5)
Andrology & Gynecology : Current Research     Hybrid Journal   (Followers: 4)
Andrology and Genital Surgery     Open Access   (Followers: 8)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 2)
Arab Journal of Urology     Open Access   (Followers: 7)
Archives of Clinical Nephrology     Open Access   (Followers: 2)
Archivio Italiano di Urologia e Andrologia     Open Access   (Followers: 1)
Archivos Españoles de Urología     Open Access   (Followers: 1)
Asian Journal of Andrology     Open Access   (Followers: 1)
Asian Journal of Urology     Open Access   (Followers: 3)
Asian Pediatric Nephrology Association     Open Access   (Followers: 3)
Bangladesh Journal of Urology     Open Access   (Followers: 5)
Basic and Clinical Andrology     Open Access  
BJU International     Hybrid Journal   (Followers: 19)
BJUI Compass     Open Access   (Followers: 1)
BMC Nephrology     Open Access   (Followers: 9)
BMC Urology     Open Access   (Followers: 13)
Canadian Journal of Kidney Health and Disease     Open Access   (Followers: 7)
Canadian Urological Association Journal     Open Access   (Followers: 1)
Cancer Urology     Open Access   (Followers: 1)
Cardiorenal Medicine     Full-text available via subscription   (Followers: 1)
Case Reports in Nephrology     Open Access   (Followers: 6)
Case Reports in Nephrology and Dialysis     Open Access   (Followers: 8)
Case Reports in Urology     Open Access   (Followers: 11)
Clinical and Experimental Nephrology     Hybrid Journal   (Followers: 5)
Clinical Journal of the American Society of Nephrology     Full-text available via subscription   (Followers: 24)
Clinical Kidney Journal     Open Access   (Followers: 5)
Clinical Medicine Insights : Urology     Open Access   (Followers: 3)
Clinical Nephrology     Full-text available via subscription   (Followers: 8)
Cuadernos de Cirugía     Open Access  
Current Opinion in Nephrology & Hypertension     Hybrid Journal   (Followers: 12)
Current Opinion in Urology     Hybrid Journal   (Followers: 11)
Current Urology     Open Access   (Followers: 10)
Current Urology Reports     Hybrid Journal   (Followers: 5)
Der Nephrologe     Hybrid Journal  
Der Urologe     Hybrid Journal   (Followers: 1)
Diabetic Nephropathy     Open Access  
EMC - Urología     Full-text available via subscription  
Enfermería Nefrológica     Open Access   (Followers: 1)
European Urology     Hybrid Journal   (Followers: 23)
European Urology Focus     Hybrid Journal   (Followers: 4)
European Urology Oncology     Hybrid Journal  
European Urology Open Science     Open Access   (Followers: 8)
Forum Nefrologiczne     Full-text available via subscription  
Geriatric Nephrology and Urology     Hybrid Journal   (Followers: 7)
Giornale di Clinica Nefrologica e Dialisi     Open Access  
Hellenic Urology     Open Access   (Followers: 4)
IJU Case Reports     Open Access  
Indian Journal of Nephrology     Open Access   (Followers: 2)
Indian Journal of Urology     Open Access   (Followers: 5)
International Brazilian Journal of Urology     Open Access   (Followers: 5)
International Journal of Nephrology     Open Access   (Followers: 2)
International Journal of Nephrology and Renovascular Disease     Open Access   (Followers: 2)
International Journal of Urology     Hybrid Journal   (Followers: 10)
International Urology and Nephrology     Hybrid Journal   (Followers: 6)
Journal für Urologie und Urogynäkologie/Österreich     Hybrid Journal  
Journal of Clinical Nephrology     Open Access   (Followers: 1)
Journal of Clinical Urology     Hybrid Journal   (Followers: 12)
Journal of Endoluminal Endourology     Open Access  
Journal of Endourology     Hybrid Journal   (Followers: 2)
Journal of Endourology Case Reports     Hybrid Journal  
Journal of Genital System & Disorders     Hybrid Journal   (Followers: 1)
Journal of Integrative Nephrology and Andrology     Open Access   (Followers: 2)
Journal of Kidney Cancer and VHL     Open Access  
Journal of Lower Genital Tract Disease     Hybrid Journal  
Journal of Nephrology     Hybrid Journal   (Followers: 5)
Journal of Nephrology Research     Open Access   (Followers: 2)
Journal of Pediatric Nephrology     Open Access   (Followers: 3)
Journal of Renal Care     Hybrid Journal   (Followers: 8)
Journal of Renal Nursing     Full-text available via subscription   (Followers: 8)
Journal of Renal Nutrition     Hybrid Journal   (Followers: 28)
Journal of Renal Nutrition and Metabolism     Open Access   (Followers: 2)
Journal of the American Society of Nephrology     Full-text available via subscription   (Followers: 38)
Journal of The Egyptian Society of Nephrology and Transplantation     Open Access  
Journal of Urology & Nephrology     Open Access  
Kidney Diseases     Open Access   (Followers: 3)
Kidney International     Hybrid Journal   (Followers: 52)
Kidney International Reports     Open Access   (Followers: 6)
Kidney Medicine     Open Access   (Followers: 1)
Kidney Research Journal     Open Access   (Followers: 6)
Kidneys (Počki)     Open Access  
Nature Reviews Nephrology     Full-text available via subscription   (Followers: 29)
Nature Reviews Urology     Full-text available via subscription   (Followers: 9)
Nefrología     Open Access  
Nefrología (English Edition)     Open Access  
Nephro-Urology Monthly     Open Access   (Followers: 1)
Nephrology     Hybrid Journal   (Followers: 13)
Nephrology Dialysis Transplantation     Hybrid Journal   (Followers: 26)
Nephron     Hybrid Journal   (Followers: 3)
Nephron Clinical Practice     Full-text available via subscription   (Followers: 3)
Nephron Experimental Nephrology     Full-text available via subscription   (Followers: 4)
Nephron Extra     Open Access   (Followers: 1)
Nephron Physiology     Full-text available via subscription   (Followers: 4)
Neurourology and Urodynamics     Hybrid Journal   (Followers: 1)
OA Nephrology     Open Access   (Followers: 2)
Open Access Journal of Urology     Open Access   (Followers: 6)
Open Journal of Nephrology     Open Access   (Followers: 4)
Open Journal of Urology     Open Access   (Followers: 6)
Open Urology & Nephrology Journal     Open Access  
Paediatric Nephrology Journal of Bangladesh     Open Access   (Followers: 4)
Portuguese Journal of Nephrology & Hypertension     Open Access   (Followers: 1)
Progrès en Urologie     Full-text available via subscription  
Progrès en Urologie - FMC     Full-text available via subscription  
Prostate Cancer and Prostatic Diseases     Hybrid Journal   (Followers: 4)
Renal Failure     Open Access   (Followers: 11)
Renal Replacement Therapy     Open Access   (Followers: 3)
Research and Reports in Urology     Open Access   (Followers: 4)
Revista de Nefrología, Diálisis y Trasplante     Open Access   (Followers: 1)
Revista Mexicana de Urología     Open Access  
Revista Urologia Colombiana     Open Access  
Scandinavian Journal of Urology     Hybrid Journal   (Followers: 6)
Seminars in Nephrology     Hybrid Journal   (Followers: 11)
The Prostate     Hybrid Journal   (Followers: 6)
Therapeutic Advances in Urology     Open Access   (Followers: 3)
Translational Research in Urology     Open Access   (Followers: 1)
Trends in Urology & Men's Health     Partially Free   (Followers: 1)
Urine     Open Access  
Uro-News     Hybrid Journal  
Urolithiasis     Hybrid Journal   (Followers: 1)
Urologia Internationalis     Full-text available via subscription   (Followers: 1)
Urologia Journal     Hybrid Journal  
Urologic Clinics of North America     Full-text available via subscription   (Followers: 3)
Urologic Nursing     Full-text available via subscription   (Followers: 3)
Urological Science     Open Access  
Urologicheskie Vedomosti     Open Access  
Urologie in der Praxis     Hybrid Journal  
Urology     Hybrid Journal   (Followers: 26)
Urology Case Reports     Open Access   (Followers: 3)
Urology Times     Free   (Followers: 3)
Urology Video Journal     Open Access  
World Journal of Nephrology and Urology     Open Access   (Followers: 5)
World Journal of Urology     Hybrid Journal   (Followers: 10)

           

Similar Journals
Journal Cover
Cardiorenal Medicine
Journal Prestige (SJR): 0.8
Citation Impact (citeScore): 2
Number of Followers: 1  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 1664-3828 - ISSN (Online) 1664-5502
Published by Karger Homepage  [122 journals]
  • Interaction between hyperuricemia and admission lactate increases the risk
           of acute kidney injury in patients with ST-segment elevation myocardial
           infarction

    • Free pre-print version: Loading...

      Abstract: AbstractBackground and Objective: Acute kidney injury (AKI) is a common complication associated with adverse outcomes among patients with ST-segment elevation myocardial infarction (STEMI). This is conflicting information about the relationship between hyperuricemia and AKI in STEMI. This work aims to investigate the effect of the interaction between hyperuricemia and lactate on the risk of AKI.Methods: We analyzed 2,008 consecutive STEMI patients between January 2014 and January 2019. Hyperuricemia was defined as a serum uric acid (SUA) level >7 mg/dl for males and >6 mg/dl for females. AKI was defined based on the Kidney Disease: Improving Global Outcomes (KDIGO). Logistic regression models were applied to establish the relationship between hyperuricemia and AKI in the overall population and subgroups stratified as per lactate levels at admission (≤ 2.2 mmol/L or > 2.2 mmol/L). Results: In total, we included 1,887 STEMI patients. Multivariate analysis showed that hyperuricemia is associated with the risk of AKI (OR: 1.34; 95% CI: 1.01-1.77; P =0.045). Nonetheless, the predictive effect of hyperuricemia was only observed in patients with lactate level > 2.2mmol/L (OR: 2.05; 95% CI: 1.36-3.10; P < 0.001), but not in those with lactate level ≤ 2.2mmol/L (OR: 0.86, 95% CI: 0.56-1.32, P = 0.493). The interaction between hyperuricemia and lactate levels demonstrated a significant effect on AKI.Conclusions: In summary, hyperuricemia increases the risk of AKI in STEMI patients with lactate levels> 2.2mmol/L, but not those with lactate levels ≤ 2.2 mmol/L.

      PubDate: Tue, 02 Aug 2022 13:34:31 +020
       
  • Roles for SGLT2 Inhibitors in Cardiorenal Disease

    • Free pre-print version: Loading...

      Abstract: Cardiovascular disease (CVD) and chronic kidney disease (CKD) share common risk factors, including type 2 diabetes mellitus (T2DM). In cardiovascular outcome studies of patients with T2DM, sodium-glucose cotransporter 2 inhibitor (SGLT2i) therapy was associated with risk reductions in cardiorenal endpoints. This article aims to provide a comprehensive overview of the efficacy of SGLT2i therapy in patients at risk of cardiorenal disease. A literature review of large outcome studies of patients who had CKD or heart failure with reduced ejection fraction (HFrEF, defined as having a left ventricle ejection fraction [LVEF]
      PubDate: Thu, 14 Jul 2022 10:59:23 +020
       
  • Catheter ablation for atrial fibrillation in patients with chronic kidney
           disease and on dialysis – a meta-analysis and review

    • Free pre-print version: Loading...

      Abstract: Background: Atrial fibrillation (AF) is common in chronic kidney disease (CKD) patients and is difficult to treat with antiarrhythmics and anticoagulants due to abnormal metabolism and increased side effects. Catheter ablation, if successful, may be a safer alternative. This review aims to analyse the effect of CKD or haemodialysis (HD) on recurrence of AF after catheter ablation . This review evaluates efficacy of catheter ablation therapy in CKD and haemodialysis (HD) patients by with single catheter ablation therapy. Methods: MEDLINE, and Embase, and Pubmed databases were searched until December 2020. Two authors abstracted the data independently. Relative risks were derived using random-effects meta-analysis. Results: Of the initially identified 520 782 studies, 65 and 34 observational studies on CKD and HD patients respectively were found reporting AF recurrence rates. During a mean (SD) follow-up of 25.5 (9.8) months, CKD patients have a higher risk of AF recurrence compared to patients without CKD (RR 2.34, 95% CI 1.36-4.02, p
      PubDate: Tue, 12 Jul 2022 16:16:36 +020
       
  • Serum and Urine Osmolality as Predictors of Adequate Diuresis in Acute
           Decompensated Heart Failure: A Prospective Cohort Study

    • Free pre-print version: Loading...

      Abstract: Abstract: BackgroundDetermination of adequacy of decongestion remains a significant challenge in the management of acute heart failure (AHF).Methods This is a prospective single center cohort study of patients (>18 years old) admitted for AHF on intravenous diuretics, with BNP > 100 pg/mL or echocardiographic findings of reduced ejection fraction or diastolic dysfunction, and at least 1 clinical sign of volume overload. Patients with eGFR≤45mL/minute or on dialysis, and with exposure to contrast dye or nephrotoxins were excluded. Serum and spot urine osmolality were obtained early morning simultaneously daily for 5 days or until discharge. ROC curves were used to analyze the optimal cut-offs for the osmolality values in the prediction of heart failure readmissionsResultsOf the total 100 patients, 62% were male and 59% were Black American. The mean age was 64.41±12.53 and 34% had preserved ejection fraction. Patients with 30-day readmission had higher serum osmolality(mOsm/kg) on admission (305 [299-310] vs 298 [294-303] p=0.044) and had higher drop in serum osmolality between admission and discharge (-7.5 [-9.0,-1.25] vs -1.0 [-4.0,4.0] ;p=0.044). Serum osmolality on admission of >299 mOsm/kg (sensitivity:83%, specificity:61%) and drop in serum osmolality between admission and discharge of >2 mOsm/kg (sensitivity:83%, specificity:65%) was associated with 30-day HF readmissions. No patients discharged with urine osmolality more than 500 mOsm/kg had 30-day readmissions but this was not statistically significant p=0.334Conclusion Measurement of serum osmolality and urine osmolality may have some utility in AHF, but interpretation should consider baseline values and dynamic changes to account for individual differences in sodium and water handling.

      PubDate: Mon, 27 Jun 2022 16:52:10 +020
       
  • Prediction of acute kidney injury for acute type A aortic dissection
           patients underwent Sun’s procedure by a perioperative nomogram

    • Free pre-print version: Loading...

      Abstract: Introduction: Postoperative acute kidney injury (AKI) occurs in 20%-40% of acute type A aortic dissection (ATAAD) patients undergoing cardiac surgery. A predictive model could be developed to assess the probability of AKI in patients with ATAAD before and after cardiac surgery in a timely manner.Methods: This retrospective study enrolled a total of 224 patients with ATAAD. Patients were subjected to total arch replacement using tetrafurcate graft with stented elephant trunk implantation according to Sun’s procedure. Statistical comparison for the collected data was done with Student’s t-test or Mann-Whitney U test (continuous variables) and chi-square test (categorical variables). The independent predictors were screened by multivariate logistic regression analysis, and then incorporated into a nomogram. The reliability of cardiac surgery-associated acute kidney injury (CSA-AKI) models was evaluated using the area under the receiver operating characteristic curve (AUC).Results: This study enrolled 224 acute type A aortic dissection patients, including 53 patients with AKI and 171 patients without AKI. The incidence of ATAAD-induced AKI in the cohort was 23.66%. The screened predictors for AKI include iliac artery involvement, creatinine, D-dimer, autotransfusion, platelet-rich plasma reinfusion, nasal temperature, red blood cells, fresh frozen plasma, drainage, and mechanical ventilation. The calculated AUC values for model 1, model 2, model 3, and model 4 were 0.710, 0.777, 0.827, and 0.848, respectively. Model 4 was optimum for AKI risk scoring compared with model 1, model 2, and model 3.Conclusions: AKI prediction models were established for ATAAD patients using preoperative, intraoperative, and postoperative information. Particularly model 4 shows superiority in risk prediction for CSA-AKI.

      PubDate: Wed, 22 Jun 2022 14:42:23 +020
       
  • ATRIAL FIBRILLATION AND ANTICOAGULANT TREATMENT IN END – STAGE RENAL
           DISEASE PATIENTS. WHERE DO WE STAND

    • Free pre-print version: Loading...

      Abstract: The frequent coexistence in daily clinical practice of chronic kidney disease (CKD) and atrial fibrillation (AF), especially in the elderly, represents a conundrum for physicians, mainly related to the management of anticoagulant therapy. The reduction of estimated glomerular filtration rate (eGFR) impairs anticoagulant clearance, increasing bleeding propensity. Moreover, dysfunctional responses of endothelial cells and inflammatory systems both trigger thromboembolic status. Those mechanisms pose AF patients with CKD to increased risk of adverse events. If several evidences suggested the use of direct oral anticoagulants (DOACs) over warfarin as preferred anticoagulant strategy in patients with moderate to severe CKD (eGFR > 30 ml/min), less is known about the optimal anticoagulation management in patients with end-stage renal disease (ESRD) or on renal replacement therapy (RRT). Furthermore, a pivotal feature to be considered when choosing the anticoagulant drug in CKD patients is represented by nephroprotective capability. Indeed, anticoagulant therapy with warfarin showed detrimental effects on kidney function, whereas DOACs demonstrated a beneficial effect on renal function preservation. Mounting evidences showed that, when pharmacological treatment cannot be pursued due to contraindication to anticoagulation, left atrial appendage occlusion (LAAO) may represent a valid alternative. This brief review outlines the current evidence regarding anticoagulation therapy in ESRD/RRT patients, reporting new evidences on nephroprotective effect of oral anticoagulants and on the use of LAAO as non-pharmacological alternative to oral anticoagulation.

      PubDate: Tue, 07 Jun 2022 11:31:46 +020
       
  • SUBCLINICAL AKI AND CLINICAL OUTCOMES IN ELDERLY PATIENTS UNDERGOING
           CARDIAC SURGERY: DIAGNOSTIC UTILITY OF NGAL VERSUS STANDARD CREATININE
           INCREASE CRITERIA

    • Free pre-print version: Loading...

      Abstract: Background: AKI is a common and serious postoperative complication in patients undergoing cardiac surgery and its incidence is particularly high among elderly patients. Cardiac surgery-associated AKI (CSA-AKI) represents the second most common cause of AKI in the intensive care unit but its true incidence could be underestimated, especially in elderly population. The current biomarkers of AKI are unreliable and delayed during acute changes in kidney function. In the setting of subclinical AKI (SAKI), biomarkers of tubular damage such as NGAL, seems to be an early indicator of kidney damage. The aim of this study was to investigate NGAL utility in the SAKI diagnosis on the first 48 hours after cardiac surgery and its helpfulness in predicting adverse clinical outcomes in comparison to current criteria for AKI. Methods: This is an observational study of 72 patients admitted to San Bortolo’s cardiac surgery department for elective cardiosurgical procedure enrolled over a 5-months period. All patients underwent peripheral venous sample 48 hours after cardiac surgery to assess plasmatic Creatinine (48Cr) and NGAL (48pNGAL) in addition to exams already foreseen by clinical practice. For each patient we studied renal, respiratory and cardiovascular outcome during hospitalization as well as 30 days and 6 months mortality. Creatinine Increase AKI (CrIAKI) was defined by 48CrI≥0.3mg/dL and Subclinical Acute kidney Injury (SAKI) was defined by 48pNGAL≥100pg/dL. We also assessed Respiratory (ArespO) as well as Cardiovascular (ACvO ) outcome.Results: 30 days mortality was 8.3% (6 patients) and 6 months mortality was 12.5% (9 patients). A total of 27 patients (37.5%) presented AKI according to KDIGO (4) and 4 (5.5%) needed RRT. SAKI was significantly associated with 30 days mortality (p=0.0238), six months mortality (p=0.002), Adverse renal outcome ARenO (p=0.004) and need for RRT (p=0.005). CrIAKI was significantly associated with 30 days mortality (p=0.009) and ARenO (p=0.0001), but not with six months mortality nor need for RRT.

      PubDate: Fri, 03 Jun 2022 10:19:58 +020
       
  • The utility of systemic immune-inflammation index for predicting
           contrast-induced nephropathy in patients with ST-segment elevation
           myocardial infarction undergoing primary percutaneous coronary
           intervention

    • Free pre-print version: Loading...

      Abstract: Objective: The systemic immune-inflammation index (SII), derived from counts of neutrophil, platelet and lymphocyte, have been developed to predict clinical outcomes in several cancers and cardiovascular diseases. The aim of this study was to evaluate the utility of SII to predict contrast-induced nephropathy (CIN) in patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI). Methods: A total of 632 patients with STEMI who underwent primary PCI were retrospectively included. The patients divided into two groups based on the presence or absence of CIN. Baseline demographic, laboratory and clinic characteristics were evaluated between the two groups. Logistic regression analysis was used to identify independent predictors of CIN.Results: The receiver-operating characteristic (ROC) curve analysis demonstrated that the optimal cut-off value of SII for predicting CIN was 1282 with a sensitivity 76.1% and specificity 86.7% (AUC: 0.834; 95% CI 0.803-0.863; p1282 (p
      PubDate: Tue, 17 May 2022 10:03:23 +020
       
  • Serum Thyrotropin Elevation and Coronary Artery Calcification in
           Hemodialysis Patients

    • Free pre-print version: Loading...

      Abstract: Introduction:Hypothyroidism is highly prevalent in end-stage kidney disease (ESKD) patients, and emerging data show that lower circulating thyroid hormone levels lead to downregulation of vascular calcification inhibitors and coronary artery calcification (CAC) in this population. To date, no studies have examined the association of serum thyrotropin (TSH), the most sensitive and specific single biochemical metric of thyroid function, with CAC risk in hemodialysis patients.Methods:In secondary analyses of patients from the Anti-Inflammatory and Anti-Oxidative Nutrition in Hypoalbuminemic Dialysis Patients (AIONID) trial, we examined serum TSH levels and CAC risk assessed by cardiac CT scans collected within a 90-day period. We evaluated the relationship between serum TSH with CAC Volume and Agatston scores (defined as >100 mm3 and >100 Houndsfield Units [HU], respectively) using multivariable logistic regression. Results:Among 104 patients who met eligibility criteria, higher TSH levels in the highest tertile were associated with moderately elevated CAC Volume and Agatston scores in case-mix adjusted analyses (ref: lowest tertile): adjusted ORs (aORs) (95%CIs) 4.26 (1.18, 15.40) and 5.53 (1.44, 21.30), respectively. TSH levels >3.0 mIU/L (ref: ≤3.0 mIU/L) were also associated with moderately elevated CAC Volume and Agatston scores. In secondary analyses, point estimates of incrementally lower direct free thyroxine levels trended towards elevated CAC Volume and Agatston scores, although associations did not achieve statistical significance.Conclusions:In hemodialysis patients, higher serum TSH was associated with elevated CAC Volume and Agatston scores. Further studies are needed to determine if thyroid hormone supplementation can attenuate CAC burden in this population.

      PubDate: Thu, 12 May 2022 14:26:14 +020
       
  • The prognostic significance of chronic kidney disease on the all-cause
           death of ischemic heart failure in the Chinese population: a prospective
           cohort study

    • Free pre-print version: Loading...

      Abstract: Objective: Our team tried to explore the impact of chronic kidney disease (CKD) on all-cause death among ischemic heart failure (IHF) patients.Methods: From December 2015 to June 2019, IHF patients were continuously recruited in the Department of Cardiology, Guangdong Provincial People's Hospital. Participants were tracked through telephone interviews until October 15, 2020, or until the clinical endpoints appeared. The clinical endpoints were defined as all-cause death. The date of death or the last follow-up date minus the discharge date were used to calculate the follow-up time.Results: A total of 1568 IHF patients (mean age 63.5 ± 11.0 years old, 85.8% male) were included in this study. Using the estimated glomerular filtration rate (eGFR) of 60 mL/min/1.73 m2 as the dividing line, IHF patients were divided into non-CKD group (n = 1134) and CKD group (n = 434). After a median follow-up of 2.1 years, the all-cause death of non-CKD and CKD patients was 6.1/100 person-years and 13.7/100 person-years, respectively, and the incidence rate ratio was 2.24 (95% CI: 1.75-2.88; P value < 0.001). The cumulative all-cause death of non-CKD and CKD patients were 19.4% and 40.7%, respectively (p value < 0.001). CKD was an independent predictor of all-cause death in IHF patients (HR: 1.35, 95% CI: 1.03-1.76, P value = 0.029). Among IHF patients, in 8 subgroups, the all-cause death of CKD patients was consistently higher than that of non-CKD patients. Among IHF patients, the risk of all-cause death gradually increased when eGFR gradually decreased.Conclusion: Among IHF patients, CKD is a significant risk factor for all-cause death.

      PubDate: Thu, 12 May 2022 08:47:03 +020
       
 
JournalTOCs
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Email: journaltocs@hw.ac.uk
Tel: +00 44 (0)131 4513762
 


Your IP address: 3.239.4.127
 
Home (Search)
API
About JournalTOCs
News (blog, publications)
JournalTOCs on Twitter   JournalTOCs on Facebook

JournalTOCs © 2009-