JournalTOCs

Journal of Musculoskeletal Research
Journal Prestige (SJR): 0.158

Number of Followers: 9

Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0218-9577 - ISSN (Online) 1793-6497
Published by World Scientific

[120 journals]

EFFECTS OF CERVICAL TRACTION AND INFRARED THERAPY ON PAIN INTENSITY AND
NECK DISABILITY INDEX AMONG PEOPLE WITH CERVICAL SPONDYLOSIS: A CROSS-OVER
COHORT STUDY
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  Authors: Augustine Asiduba Igwe, Ogochukwu Kelechi Onyeso, Charles Ikechukwu Ezema, Gabriel Okey Eyichukwu, Emmanuel Chukwudi Ejim, Victor A. Egwuonwu, Obinna Onwujekwe, Amaeze Augustine Amaeze, Goddy Chuba Okoye
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Objective: To investigate the effects of six-week cervical traction and infrared therapy on neck pain intensity (PI) and neck disability index (NDI) among individuals with cervical spondylosis. Methods: This study was a non-randomized cross-over cohort design. A total of 40 participants (men=20, and women=20) who were purposively selected, received a six-week infrared therapy, observed a one-week washout period, and then six-week concurrent infrared therapy and cervical traction. The PI and NDI were measured at baseline, after infrared therapy, the washout period, and infrared plus cervical traction. Data were analyzed using repeated-measures analysis of variance (RM ANOVA), Friedman’s ANOVA, independent samples [math]-test, and Kendall’s tau correlation test. Result: The mean age of the participants was 40±8.60 years. Infrared therapy plus cervical traction significantly reduced PI: [math]2(3) = 102.06, [math] < 0.001, and NDI: [math](1, 39) = 222.56, [math] < 0.001, relative to infrared therapy alone. Specifically, the minimum clinically important difference (MCID) for PI was 2.2, while infrared alone reduced the PI by 1.0 ([math] = 4.633, [math] < 0.001), infrared therapy plus cervical traction reduced PI by 6.0 ([math]= 7.405, [math] < 0.001). The MCID for NDI was 8.50, while infrared alone reduced the NDI by 1.05 ([math]= 30.087, [math] < 0.001), infrared therapy plus cervical traction reduced NDI by 15.83 ([math] = 14.644, [math] < 0.001). Conclusion: Concurrent infrared and cervical traction significantly reduced PI and NDI among patients with cervical spondylosis more than lone infrared therapy.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-08-03T07:00:00Z
  DOI: 10.1142/S0218957722500233
DISTAL TIBIA SOLITARY OSTEOCHONDROMA-A CASE SERIES
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  Authors: Ramniwas Bishnoi, Hemant Jain, Nandlal Bharwani, Jayesh Chouhan, Pradeep Choudhary, Mahesh Bhati
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Introduction: Distal tibia involvement is very rare and it merely accounts for around 4% of all the excised lesions. (Mirra, 1989) Distal tibia osteochondromas mainly present pain, deformity like varus/valgus around ankle joint, pathologic fractures of surrounding structures and for the above-mentioned problems, surgical excision has to be considered as a possible option. (Ismail et al., 2008). Methods: We conducted a prospective study from 1st June 2018 to 1st June 2021 including five patients (4 males and 1 female) with distal tibia osteochondroma. In our study, surgical excision was performed in all the cases. Pre-operative and at final follow-up ‘AOFAS-AHFS score’ and ‘VAS score’ were evaluated. Results: All five patients had good functional outcome at final follow-up, mean AOFAS-AHFS score improved from 61.2±5.4 to 85±3.39, and mean VAS score improved from 7.2±0.83 to 0.8±0.44 at final follow-up and found no difficulty in daily routine activities. All patients had complete ROM at final follow-up. Conclusion: Distal tibia osteochondroma has good functional outcome and less complications, if managed properly.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-08-03T07:00:00Z
  DOI: 10.1142/S0218957722500294
DOES REAL ACUPUNCTURE PRODUCE THE SAME EFFECT AS PLACEBO ACUPUNCTURE ON
SENSORY PERCEPTION' A RANDOMIZED CONTROLLED CLINICAL TRIAL
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  Authors: Leonardo Y. S. Maciel, Mauricio L. P. Neto, Paula Michele S. Leite, Andreza C. R. Mendonça, Mylena Maria S. Santana, Carla Carolina A. Araujo, Jersica H. S. Souza, Érika Thatyana N. Santana, Josimari M. DeSantana
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Background : Acupuncture treatment has become increasingly popular in the Western due to its therapeutic effects and low cost. However, some studies suggest that both real and sham acupuncture have effects. Objectives: Our study aimed to evaluate the effect of real and placebo acupuncture in cutaneous and deep sensitivity threshold. Methods: Three different types of placebo acupunctures were compared with real acupuncture, four groups at the St25 point (abdominal) and four at the Bl52 point (lumbar region), totaling eight groups. 185 subjects were recruited and randomized, ratings of cutaneous sensitivity threshold (von Frey filaments) and pressure pain threshold (algometer) occurred before and after the application. Results: The cutaneous sensitivity threshold showed no significant difference in the intragroup analysis and also compared between groups. The pressure pain threshold showed a significant decrease in values in the Real group Bl52 ([math] = 0.044) and insertion and removal Bl52 ([math] = 0.037) for intra-group analysis and comparison between groups, there was a significant reduction in Real groups St25 and insertion and withdrawal in Bl52 point compared to Park Sham Bl52 and Real Bl52, respectively ([math] [math] 0.05). Conclusion: Cutaneous sensitivity threshold did not change after applying acupuncture or placebo, but these techniques influence the pressure pain threshold.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-07-30T07:00:00Z
  DOI: 10.1142/S0218957722500221
THE EFFECTIVENESS OF MYOFASCIAL RELEASE VERSUS KINESIOTAPING IN LATERAL
EPICONDYLITIS
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  Authors: Archana Khanna, Rita Sharma, Sini Sam
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Purpose: The purpose of the study is to compare the clinical efficacy of myofascial release (MFR) and kinesiotaping (KT) on pain intensity, grip strength and functional limitation in lateral epicondylitis (LE). Methods: 60 patients who fulfilled the inclusion criteria were randomly allocated to two groups: MYF and KIN. In MYF group ([math]), the subjects were treated with MFR technique and conventional physiotherapy whereas in KIN group ([math]), subjects received KT and conventional physiotherapy. The intervention was given 4 days/week for 4 weeks. Outcome measures included numeric pain rating scale (NPRS), handgrip strength and patient rated tennis elbow evaluation (PRTEE) score. These measures were recorded pre- and post-intervention after 4 weeks. Results: Paired and unpaired [math]-test was used for statistical analysis. Both the groups showed statistically significant improvement in the outcomes measures but MYF group had better improvement in functional limitation (PRTEE) ([math])) and NPRS ([math]) as compared to KIN group. Conclusion: The study demonstrates that MFR is more effective in decreasing pain, functional disability and improving grip strength in LE as compared to KT.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-07-27T07:00:00Z
  DOI: 10.1142/S0218957722500191
SURGICAL TECHNIQUE AND CLINICAL BENEFITS IN FULL-ENDOSCOPIC TRANS-KAMBIN
TRIANGLE LUMBAR INTERBODY FUSION (KLIF): A REVIEW
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  Authors: Koichi Sairyo, Masatoshi Morimoto, Kazuta Yamashita, Fumitake Tezuka, Kosuke Sugiura, Makoto Takeuchi, Shunsuke Tamaki, Takuma Abe, Kohei Ota, Shinya Nakagawa, Takashi Inokuchi, Junzo Fujitani
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Full-endoscopic surgery started as discectomy via the transforaminal route toward the end of the 20th century. The interlaminar route was subsequently used for herniated nucleus pulposus at the L5/S1 level in patients with an anatomically high iliac crest. Thus, two full-endoscopic approaches are described in the literature. Furthermore, the surgical indications have expanded from discectomy to decompression and, most recently, to interbody fusion. The term used to describe interbody fusion surgery performed via the transforaminal route using a facet-preserving technique is trans-Kambin fusion (KLIF) and that used to describe such surgery when performed after facetectomy using the interlaminar technique is transforaminal lumbar interbody fusion (TLIF). Therefore, we have agreed the nomenclature of full-endoscopic facet-preserving KLIF and full-endoscopic facet-sacrificing TLIF. We have been performing full-endoscopic KLIF surgery since 2018. This review describes the surgical technique used for full-endoscopic KLIF, its clinical outcomes, and how it differs from full-endoscopic TLIF.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-06-13T07:00:00Z
  DOI: 10.1142/S0218957722400061
ACCURACY OF INTRAOPERATIVE COMPUTED TOMOGRAPHY NAVIGATION IN ONE
REGISTRATION SCAN FOR ADOLESCENT IDIOPATHIC SCOLIOSIS
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  Authors: Meng-Huang Wu, Christopher Wu, Ching-Yu Lee, Yen-Yao Li, Tsung-Jen Huang
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Purpose:Pedicle screw insertion in a deformed and rotated pedicle in scoliosis is technically demanding. A multislice spiral intraoperative computed tomography (iCT)-guided navigation system can assist pedicle screw insertion. However, no studies have been performed to evaluate the pedicle diameter and accuracy of pedicle screw placement in patients with adolescent idiopathic scoliosis (AIS) using one scan iCT-guided navigation. Methods:This was a retrospective cohort study. iCT was performed before screw insertion and after screw insertion. The pedicle diameters in all planned surgical levels were measured. A pedicle with a maximal diameter of less than 4 mm was considered narrow. A screw with a breach distance of [math]2 mm was considered accurate. Results:Twenty-nine consecutive patients with AIS received surgery with 415 pedicle screws inserted in 580 planned screw insertion pedicles. Twenty-five patients had been found to have narrow pedicles (86.2%). Overall, the screw accuracy rate was 98.6% (409/415). Thirty-eight screws were inserted in narrow pedicles and the screw accuracy was 84.2% (32/38). There were no major complications after screw insertion. Conclusion:One scan iCT-guided navigation provides a high degree of safety and screw accuracy of 98.6% for pedicle screw placement in AIS.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-06-04T07:00:00Z
  DOI: 10.1142/S021895772240005X
EDITORIAL: THE LATEST ADVANCES IN MINIMALLY INVASIVE SPINE SURGERY
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  Authors: Tsung-Jen Huang, Po-Quang Chen
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-06-03T07:00:00Z
  DOI: 10.1142/S0218957722030014
FULL-ENDOSCOPIC TRANSFORAMINAL DECOMPRESSION TO TREAT A HIGH-RISK PATIENT
WITH LUMBAR SPINAL STENOSIS AND DEGENERATIVE SPONDYLOLISTHESIS: A CASE
REPORT AND LITERATURE REVIEW
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  Authors: Pin-Yang Huang, Meng-Huang Wu, Tsung-Jen Huang, Ching-Yu Lee
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Lumbar spinal stenosis (LSS) with degenerative spondylolisthesis (DS) is prevalent in the aging population while they often have multiple comorbidities which are related to the higher risk for general anesthesia. Full-endoscopic transforaminal decompression (FETD) has been utilized under local anesthesia to remove herniated intervertebral disc, resect hypertrophic ligament and enlarged bone spur in order to decompress the affected neural structure without compromising the stability. In this study, we would present that a 71-year-old male patient, who had multiple comorbidities, underwent FETD to treat LSS with DS. We also conducted literature review to illustrate the feasibility of FETD in the treatment of LSS with DS. Reviewing 80 patients with LSS and DS in the four case-series studies, there was no difference in vertebral slippage percentage before and after operation. The overall complication rate was 3.75%, including three patients who had small dural tears which did not develop neurological sequelae during the follow-up period and did not require surgical or medical intervention. Four patients (5%) underwent reoperation due to recurrent or persistent sciatica symptoms. In conclusion, FETD can not only provide complete decompression but also maintain the original stability in treatment of LSS with DS. FETD can be an effective and safe approach to treat lumbar spinal stenosis with degenerative spondylolisthesis and can be an alternative for patients with multiple comorbidities or high risks for general anesthesia.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-06-03T07:00:00Z
  DOI: 10.1142/S0218957722400024
LATEST ADVANCES IN MINIMALLY INVASIVE SPINE SURGERY FOR TREATMENT OF
INFECTIOUS SPONDYLITIS
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  Authors: Hsien Chao, Tsung-Ting Tsai, Yu-Cheng Yeh, Ping-Yeh Chiu, Fu-Cheng Kao, Ming-Kei Hsieh, Po-Liang Lai, Tsai-Sheng Fu, Chi-Chien Niu
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Nowadays, minimal invasive surgery (MIS) plays an important role in the treatment of infectious spondylitis. This paper reviews the current options in MIS techniques and discusses the surgical outcomes from a series of cases at our department. Demographic characteristics and pre-operative clinical status of 21 patients with MIS for multilevel infectious spondylitis were analyzed; also, pre- and post-operative X-rays were assessed for surgical correction angles and fusion status. The results indicated that percutaneous endoscopic debridement (PEDD) and drainage has the advantages of less blood loss and shorter recovery time. Overall, percutaneous screw system can preserve paravertebral soft tissue, reduce post-operative pain, and foster early post-operative mobilization. Robot-assisted percutaneous screw placement is more accurate than using free-hand. Cortical bone trajectory (CBT) screw requires less surgical exposure while preserving adequate strength. Endoscopic lumbar interbody fusion (Endo-LIF) is an alternative fusion technique to treat spondylitis because it offers better functional prognosis than minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in the treatment of degenerative lumbar diseases. All the enrolled patients via MIS-TLIF obtained good surgical outcomes. Various minimally invasive techniques have been evolved and modified, so it is important for spine surgeon to keep up to date with advanced orthopedic knowledge and surgical techniques.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-06-02T07:00:00Z
  DOI: 10.1142/S0218957722400036
NATIONWIDE SURVEY ON INCIDENTAL DURAL TEARS DURING ENDOSCOPIC SPINE
SURGERY IN JAPAN
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  Authors: Akira Dezawa, Kouichi Sairyo, Hiroaki Nakamura
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Purpose: The Japanese Orthopedic Association has conducted a nationwide survey on the status of endoscopic spine surgery in Japan every year since 2006. This study aimed to analyze incidental dural tear. Method:We sent questionnaires to all spine surgery hospitals in Japan and received responses from an average of 1296 hospitals (974–1746) each year. The average response rate for the questionnaire was 63.7% (45.2–85.8). Results:The average number of facilities performing endoscopic spine surgery was 314 (222–415). The percentage of facilities performing endoscopic procures was 24.3% (20.3–27.3%). Incidental dural tear accounted for 65.4% (3113/4758) of all complications, which was significantly higher than nerve root injuries, cauda equina injuries (4.6%), and hematomas (10.0%). The number of accidents resulting in harm to patients was 154 (3.6%) for incidental dural tear which was significantly less than that for hematoma (75.5%) and for nerve root cauda equina injury (49.5%). Conclusion:As the number of endoscopic procedures increased, the number of complications increased year by year. However, the rate of complications has remained constant, with incidental durotomy tending to be the most common endoscopic lumbar laminectomy for lumbar spinal canal stenosis.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-06-02T07:00:00Z
  DOI: 10.1142/S0218957722400048
CERVICAL DISC HERNIATION AND FORAMINAL STENOSIS
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  Authors: Hyeun Sung Kim, Pang Hung Wu, Ji Yeon Kim, Yeon Jin Lee, Jun Hyung Lee, Jun Bok Jeon, Il-Tae Jang
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Objective: Limited literature on the effect on clinical and radiological outcomes in cervical endoscopic spine surgery replacing a large percentage of open and microscopic minimally invasive surgery on outcomes in patients for cervical disc herniations and foraminal pathologies. Methods: Retrospective comparative cohort study of two periods of 2015 to 2017 (first generation) is compared to 2018–2020 (second generation) on surgical treatment of degenerative cervical spinal conditions for 132 spinal cases. Basic demographics, preoperative, post-operative 1 week, 3 months and final follow-up of patients’ clinical outcomes in terms of Visual Analog Scale Pain Score, Neck Disability Index, Japanese Orthopaedic Association Score and MacNab’s Criteria were evaluated. Results: In the first generation, 50 cases of cervical disc herniation and foraminal stenosis with 70% open anterior cervical discectomy fusion or disc replacement 30% of the cases underwent posterior cervical endoscopic procedures with complication rate of 2%. In the second generation, 82 cases of cervical disc herniation and foraminal stenosis with 7% open anterior cervical discectomy fusion or disc replacement 93% of the cases underwent posterior cervical endoscopic procedures with complication rate of 6%. Compared to preoperative score, motor, JOA, VAS and NDI scores all statistically significant improved within the individual cohort. Compared to the first generation, the second generation has statistically significant improved VAS of 0.326+/−0.146 at 3 months and 0.648+/−0.163 at final follow-up and statistically significant improved NDI of 2.81+/−1.15 at final follow-up, [math] < 0.05. Conclusions: Generation change of increasing percentage of endoscopic surgeries and expansion of endoscopic spinal indications over open surgeries in degenerative spinal conditions and disc herniations are possible as a surgeon gets more experience with endoscopic spine surgery producing good clinical outcomes.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-05-31T07:00:00Z
  DOI: 10.1142/S0218957722400012
ASSOCIATION AMONG FUNCTION-RELATED TESTS, PAIN, AND DEMOGRAPHIC DATA IN
INDIVIDUALS WITH SHOULDER DISORDERS
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  Authors: Prasert Sakulsriprasert, Rachaneewan Adisaiphaopan, Sarawut Suwannarat, Thachakorn Sa-ngounsak, Pathtarajaree Junsiri, Kamonwan Praoprirtpirom, Chompunoot Suwanasri
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Background: Function-related tests for shoulder disorders are probably related to pain and demographic data which need to be investigated. This paper aimed to study the associations among function-related tests, pain, and demographic data in individuals with shoulder disorders. Methods: The demographic data, pain by numerical rating scale (NRS), and function-related tests which are hand behind neck (HBN) and hand behind back (HBB) tests were collected. The associations were analyzed using the Spearman correlation coefficient and point-biserial correlation. Results: Five hundred sixty-six individuals with shoulder disorders participated. High significant association was reported between HBN and HBB ([math], [math]). Also, NRS ([math] –0.196, [math] –0.237), age ([math] –0.258, [math] –0.241), number of underlying diseases ([math] –0.161, [math] –0.171), and diabetes mellitus (DM) ([math] –0.124, [math] –0.143) had significant correlations with HBN and HBB tests. Conclusion: The association among HBN, HBB, NRS, age, number of underlying diseases, and DM reflected the importance of pain management and the considerations of the patient’s background involving age and underlying diseases.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-05-31T07:00:00Z
  DOI: 10.1142/S0218957722500208
ULTRASONOGRAPHIC EVALUATION OF MORPHOLOGICAL CHANGES IN THE INFRAPATELLAR
FAT PAD DURING KNEE EXTENSION
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  Authors: Hayato Kawaji, Mitsuhiro Aoki, Masahiro Yamane, Yoshiaki Kataoka
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Purpose: To investigate morphological changes in the infrapatellar fat pad (IPFP) during active knee extension using ultrasonography. Methods: IPFP deformity from 30∘ knee flexion to full extension was recorded using ultrasonography. IPFP thickness and patellar tendon-tibial angle were evaluated on 26 healthy knees in the first session and nine knees in the second session. Intra-rater and inter-rate reliability were evaluated using coefficient of variation (CV) and intraclass correlation coefficient (ICC) of types (1, 3) and (2, 3), respectively. Absolute reliability was assessed using the standard error of measurement (SEM). Changes in the patellar tendon-tibial angle and IPFP thickness were analyzed using paired [math]-test. Results: At each knee angle, ICC (1, 3) was [math] for the patellar tendon-tibial angle and IPFP thickness (CV [math]). Compared to 30∘ knee flexion, the patellar tendon-tibial angle increased significantly from 33.3∘ to 38.9∘ ([math]). The IPFP thickness significantly increased from 4.4[math]mm to 5.3[math]mm with active knee extension ([math]), without overlap of the 95% CI of SEM. For inter-rater reliability, ICC (2, 3) was [math] for each variable (CV [math]). Conclusions: Increased IPFP thickness during active knee extension indicates IPFP deformity in the anterior interval. Ultrasonography may help evaluate morphological changes and estimate IPFP scarring.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-05-11T07:00:00Z
  DOI: 10.1142/S021895772250021X
DISTAL HUMERUS FRACTURES MANAGED WITH OPEN REDUCTION AND INTERNAL FIXATION
OR TOTAL ELBOW ARTHROPLASTY RESULT IN SIMILAR RANGE OF MOTION AND
REOPERATION RATES
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  Authors: Amber Gordon, Shaan Patel, Kyle Achors, Evan Horowitz, Carson Smith, Jason Nydick
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Introduction: The purpose of our study was to evaluate complications in intraarticular distal humerus fractures in patients above 50 years of age treated with either total elbow arthroplasty (TEA) or open reduction and internal fixation (ORIF). Methods: Between 1999 and 2018, 54 patients, underwent either TEA (27 patients) or ORIF (27 patients) for a distal humerus fracture at a Level 1 trauma center. Pre-operative variables, including mechanism of injury, open or closed fracture, AO/OTA fracture classification, and nerve palsy, were recorded. Main outcomes measurements included postoperative complications and reoperation. Results: Average follow up was 3.3 years for the TEA group and 1.0 year for the ORIF group. The TEA group had 28 complications in 23 total patients Fourteen complications were minor and did not require reoperations. Twelve patients had a major complication requiring reoperation. The ORIF group had 25 complications in 17 patients. Twelve complications were minor and did not require operation. Twelve patients sustained a major complication requiring reoperation. Conclusion: Patients above 50 years of age with intraarticular distal humerus fractures managed with TEA or ORIF have similar reoperation and complication rates.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-04-19T07:00:00Z
  DOI: 10.1142/S0218957722500075
ULTRASOUND-GUIDED PLATELET-RICH PLASMA INJECTION THERAPY IN PARTIAL
THICKNESS ROTATOR CUFF TEARS: LONG-TERM RESULTS
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  Authors: Shubham Agarwal, Hemant Jain, Kishore Raichandani, H. S. Ujjwal, Amit Singh
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Introduction: Rotator cuff tendinopathy/partial tear is the most common cause of shoulder pain encountered in clinical practice. The treatment varies from conservative to surgical options. Recently there has been extensive use of blood-derived products for the healing of tendon injuries. Platelet-rich plasma (PRP) is hypothesized to augment tendon healing due to various growth factors including PDGF, VEGF and TGF-b. While the theoretical explanations look promising, the clinical efficacy of PRP is conflicting, thus establishing a clear need for extensive studies. Aim: The purpose of this study is to evaluate the results of the use of PRP in patients having partial rotator cuff tears. Material and Methods: Fifty patients of the age group 25–50 years who had partial cuff tears ([math] involvement) identified on Magnetic Resonance Imaging (MRI) and had continuous pain for a minimum three months were studied. They were treated with PRP therapy and the results of their function were evaluated over time. Results: Shoulder function assessment was done was UCLA and Quick DASH score. Each of these scores showed a statistically significant improvement at 6 and 12 months. The Mean UCLA score pre-procedure was [math] and at final follow-up was [math]. There was reduction in the average Quick DASH score from [math] pre-therapy to [math] at 12 months follow-up. Conclusion: After the final follow-up, most of the patients were able to resume their daily activities. The world of PRP therapy looks promising and is needed to be explored further in orthopedics as a lot of controversy over its benefits exists in the literature.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-04-06T07:00:00Z
  DOI: 10.1142/S0218957722500178
EFFECT OF PLATELET-RICH FIBRIN ON BIOMECHANICAL AND BIOCHEMICAL ASPECTS OF
TENDON HEALING: A PRELIMINARY ANIMAL STUDY
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  Authors: Amir Reza Yousefi, Davoud Kazemi, Mostafa Rezaei
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Purpose: To investigate the effect of platelet-rich fibrin as a rich source of growth factors on biomechanical and biochemical aspects of tendon healing. Methods: Tendon defects were created in six adult male mixed breed dogs by surgical resection of the central third of the patellar tendon of both hind limbs. The defects were either treated by platelet-rich fibrin implantation or left empty. The animals were euthanized one, three and six months after surgery and their patellar tendons harvested for determination of ultimate stress, ultimate strain, tensile strength and Young’s modulus of elasticity along with hydroxyproline content. Results: Significant differences were not observed in mean values of the measured biomechanical and biochemical parameters at any time point between the two groups. Conclusions: Based on the results of the present study, PRF did not have a positive influence on biomechanical and biochemical aspects of tendon healing in dogs.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-03-30T07:00:00Z
  DOI: 10.1142/S0218957722500166
DISTAL TIBIA SPIRAL AND COMMINUTED FRACTURES: CAN ABSOLUTE ANATOMICAL
REDUCTION BE COMPROMISED'
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  Authors: Sharath K. Ramanath, Ashwini Varadha Rajan, Rahul Hemant Shah, Vanchhit Singh
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Purpose: Minimally invasive plate osteosynthesis (MIPO) is used for the treatment of distal tibial fractures, especially in cases of intra-articular fractures. There are many advantages of MIPO, including preservation of blood supply to the fracture site and enhanced bone healing, however, it is not without complication. The study aimed to elaborate the benefits of MIPO technique in managing distal tibia fractures and to describe the necessities for good union and functional outcome. Methods: A total of 38 patients with distal tibia comminuted and spiral fractures, having closed distal tibia AO/OTA 43-A, B or C fractures with or without fibular fractures, were included. All the cases were assessed for union time, complications and functional outcomes. Binomial regression using [math] v3.6.0 was used to assess the success of MIPO based on four-cortex alignment. [math] value [math] was considered statistically significant. Results: The mean operative time was 70[math]min. All 38 tibial fractures united and the mean union time was found to be 18 weeks. Five cases were noted to have complications (four superficial infections and one implant failure). Out of 38 patients, 28 (majority) showed excellent functional outcomes as assessed by the American Orthopaedic Foot and Ankle Society score, i.e. a score of [math]90. Conclusion: MIPO is a good method for the management of tibial fractures with extra-articular and intra-articular involvement, with good union even when absolute four cortical contact is not achieved.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-03-30T07:00:00Z
  DOI: 10.1142/S021895772250018X
BONE DEFECT MANAGEMENT AND AUGMENTATION OF DISTAL FEMORAL FRACTURES WITH
POLYMETHYLMETHACRYLATE BONE CEMENT
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  Authors: Sebastián Corró, Enrique García-Albó, José Vicente Andrés-Peiró, Jordi Teixidor, Jordi Tomás
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Fragility distal femoral fractures are often associated to deficient bone stock and bone defect. Frail patients, who are characterized by their coexisting comorbidities, low functional status and frequent cognitive impairment, benefit from early intervention and mobilization. The use of polymethylmethacrylate bone cement in the case of distal femoral fractures with decreased screw purchase and bone defect is a valid option in frail non-ambulatory patients. Given an accurate patient selection, the immediate postoperative mobilization provided by the one-shot surgery presented in this paper procures substantial advantages.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-03-04T08:00:00Z
  DOI: 10.1142/S0218957722500130
COMPARATIVE EVALUATION OF EFFICACY OF PERCUTANEOUS INTRADISCAL
RADIOFREQUENCY ABLATION AND PLATELET RICH PLASMA INJECTION FOR DISCOGENIC
LOW BACK PAIN: A PROSPECTIVE RANDOMIZED TRIAL
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  Authors: Titiksha Goyal, Anil Kumar Paswan, Dhruv Jain, Nimisha Verma, Rajeev Kumar Dubey
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Background: Discogenic pain is a common, yet underdiagnosed cause of low backache, for which a wide array of radiofrequency (RF) ablative techniques and regenerative therapies have been tried with variable results. The objective of the study was to compare pain relief and improvement in function between percutaneous intradiscal RF ablation and platelet-rich plasma (PRP) injection for the treatment of discogenic low backache. Methods: This double-blind, randomized, parallel-group interventional study was carried out in patients with chronic lumbar discogenic pain. Twenty-four patients each in percutaneous intradiscal radiofrequency (PIRF) ablation (Group R) and PRP injection (Group P) groups were analyzed. Numeric Rating Scale (NRS) and Oswestry Disability Index (ODI) were calculated before the procedure, and at 3 and 6 months after the procedure. Results: At 3 months, NRS score was significantly less in group R compared to group P ([math]). However at 6 months, there was no statistically significant difference between NRS and ODI of both groups ([math] and 0.369, respectively). Both NRS and ODI decreased significantly over 6 months within each group. Conclusion: No significant difference in efficacy of PIRF ablation and intradiscal PRP injection was observed at 6 months follow-up, although there was a significant improvement in pain and disability with both the procedures.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-03-03T08:00:00Z
  DOI: 10.1142/S0218957722500099
FAST-TWITCH MUSCLE FIBERS HYPERTROPHY IS HAMPERED BY ANTIOXIDANT
SUPPLEMENTATION DURING ATROPHY REHABILITATION IN RATS
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  Authors: Maurilio T. Dutra, Beshoy Girgis, Antonio Bovolini, José Alberto R. Duarte
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  The role of antioxidant supplementation on muscle recovery after disuse is unknown. The aim was to investigate the effect of Vitamin C and E supplementation on muscle recovery after hindlimb suspension. Twenty-two Wistar rats were allocated into 4 groups: exercise with supplementation (VIT, [math]); exercise with placebo (PLA, [math]); hindlimb suspension (SUSP, [math]), and control (CON, [math]). All groups, except for CON, were submitted to a hindlimb suspension protocol for 10 days. Then, VIT and PLA underwent 10 days of a rehabilitation protocol consisting of exercise on a treadmill. VIT received vitamin C (250 mg/kg/day) and E (360 mg/kg) during rehabilitation. Samples of soleus and tibialis anterior were prepared for cross-sectional area (CSA) and biochemical analysis. Both VIT (1265.6[math]m[math]2, 95% CI: 1234.6–1290.3) and PLA (1280.9[math]m[math]2, 95% CI: 1296.4–1354.9) presented higher CSA of the soleus in relation to CON (816.66[math]m[math]2, 95% CI: 866.3–904.0, [math] [math] 0.05) with no difference between them. Both VIT (1276.9[math]m[math]2, 95% CI: 1378.7–1484.6) and PLA (1573.3[math]m[math]2, 95% CI: 1553.9–1651.5) presented higher tibialis anterior CSA in relation to CON (1041.56[math]m[math]2, 95% CI: 1119.1–1185.2, [math] [math] 0.05). In this muscle, CSA of PLA was higher than VIT ([math] [math] 0.05). Vitamin’s supplementation attenuated tibialis anterior hypertrophy following the rehabilitation protocol.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-03-03T08:00:00Z
  DOI: 10.1142/S0218957722500117
BONE TURNOVER IMBALANCE IN RHEUMATOID ARTHRITIS: RELATIONSHIP BETWEEN
TUMOR NECROSIS FACTOR-[math] AND DICKKOPF-1 WITH BONE TURNOVER MARKERS
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  Authors: Faisal Parlindungan, Rudy Hidayat, Sumariyono Sumariyono, Sukamto Koesnoe
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to bone loss due to an imbalance of the bone turnover process that could be evaluated using bone turnover markers. Inflammation in RA is mainly mediated by Tumor necrosis factor-[math] (TNF-[math]) that will increase osteoclastogenesis. In recent studies, Dickkopf-1 (DKK-1) is a key regulatory pathway for bone formation that affects osteoblastogenesis. Objective: This study aims to examine the imbalance of the bone turnover process in RA patients. Methods: This was a cross-sectional study with 38 subjects of premenopausal women with RA. Serum levels of TNF-[math], DKK-1, and bone turnover markers (CTx and P1NP) were investigated. Result: The median duration of RA in this study was 5 years with 60.5% of subjects in remission or with low disease activity. The median value of TNF-[math] was 10.6 pg/mL, the mean value of DKK-1 was 4027[math]pg/mL, the mean value of CTx was 2.74[math]ng/mL, and the mean value of P1NP was 34[math]pg/mL. This study revealed a weak positive correlation between TNF-[math] and P1NP ([math]; [math]). Conclusion: This study found a low level of TNF-[math], a high level of DKK-1, a high level of CTx and a low level of P1NP that indicates an imbalance of bone turnover process in RA patients that is in favor of bone resorption.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-03-03T08:00:00Z
  DOI: 10.1142/S0218957722500129
FUNCTIONAL OUTCOME OF MEDIAL SUBTALAR DISLOCATION WITHOUT ARTICULAR
FRACTURES
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  Authors: Nandlal Bharwani, Pradeep Choudhary, Hemant Jain, Kishore Raichandani, Jagdish Godara, Medhavi Saxena
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Introduction: Subtalar dislocation is a rare injury around foot and ankle. Most common mode of injury is high-energy trauma (road traffic accident (RTA), fall from height (FFH) and sports activities) (Saini R, Dhillon MS, Gill SS. Congenital subtalar dislocation — a case report. Foot 19; Kaufmann RA, Davidson R, McCarthy J. Bilateral congenital subtalar dislocation: a case report. Clin. Orthop. Related Res. 397). It is commonly seen in young men and the mechanism is inversion injury in plantar-flexed foot. Medial-type dislocation is most commonly seen with incidence between 65% and 85%, as stated in various studies. Pure ligamentous injuries have shown good prognosis, which when associated with fractures can affect the functional outcome. Methods: We conducted a prospective study from 1st January 2017 to 1st December 2020 including seven patients (five males and two females) with closed medial subtalar dislocation with (1) or without fractures (6). In our study, closed reduction was performed in all the cases. At final follow-up, functional outcome was evaluated using ‘AOFAS-AHFS Score’ and radiological assessment. Results: All seven patients had good functional outcome at final follow-up and found no difficulty in doing daily routine activities. Routine clinical and radiological assessments were also done at final follow-up. All patients had complete ROM at final follow-up. Conclusion: Closed medial subtalar dislocation without significant articular fractures has good outcome in terms of function if managed properly.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-03-02T08:00:00Z
  DOI: 10.1142/S0218957722500063
THE IMPACT OF MICROENDOSCOPIC DECOMPRESSION ON LOW BACK PAIN IN PATIENTS
WITH DEGENERATIVE LUMBAR SPONDYLOLISTHESIS
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  Authors: Takato Aihara, Atsushi Kojima, Kenji Endo, Yasunobu Sawaji, Hidekazu Suzuki, Hirosuke Nishimura, Kazuma Murata, Takamitsu Konishi, Kengo Yamamoto
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  The same surgeon used microendoscopic decompression (MED) for all 70 patients with degenerative lumbar spondylolisthesis (DS). During the same period, fusion was not performed. Clinical outcomes were evaluated by the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ) and visual analogue scale (VAS). Standing maximal flexion-extension lateral radiographs were obtained before and after MED to measure the intervertebral angles and percentages of slipping. The mean duration of follow-up was 47.5 months. The effectiveness rate of low back pain (LBP) was the highest among all five functional scores of the JOABPEQ. LBP, pain and numbness in the buttocks and lower limb as measured by the VAS were significantly improved on follow-up evaluation. Improvements in LBP were significantly correlated with improvements in all other functional scores of the JOABPEQ and with improvements in pain and numbness in the buttocks and lower limb scores of the VAS. However, neither spondylolisthesis nor motion on flexion/extension (MFE) before and after MED influenced the improvement in LBP and the LBP after MED. The presence of LBP before MED did not lead to poor outcomes. Residual LBP was not related to residual spondylolisthesis or MFE or the development of increased spondylolisthesis postoperatively; however, residual LBP was significantly related to other residual disturbances.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-03-02T08:00:00Z
  DOI: 10.1142/S0218957722500087
COMPARISON OF UTILITY SCORES OF HIP ARTHROPLASTY FOR DYSPLASTIC
OSTEOARTHRITIS
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  Authors: Akihiro Hino, Nobuhiro Kaku, Hiroaki Tagomori, Shinichi Ikeda, Hiroshi Tsumura
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Purpose: This study aimed to compare the utility score of dysplastic osteoarthritis of the hip (OA) after different surgical treatments. Methods: In this cross-sectional study, we evaluated the utility scores of 204 patients using the Short Form-6 Dimension. Results: Utility scores of all surgery types were significantly higher than those preoperatively in OA ([math]). The utility scores of the unilateral primary total hip arthroplasty (THA) were significantly higher than those of the revision THA. Conclusions: Although THA and osteotomy are effective surgical procedures, lifetime treatment plans should be considered to avoid revision surgery as far as possible.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-02-26T08:00:00Z
  DOI: 10.1142/S0218957722500105
FUNCTIONAL OUTCOME OF MEDIAL SUBTALAR DISLOCATION WITHOUT ARTICULAR
FRACTURES
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  Authors: Nandlal Bharwani, Pradeep Choudhary, Hemant Jain, Kishore Raichandani, Jagdish Godara, Medhavi Saxena
  Abstract: Journal of Musculoskeletal Research, Ahead of Print.
  Introduction: Subtalar dislocation is a rare injury around foot and ankle. Most common mode of injury is high energy trauma (road traffic accident, fall from height and sports activities) (Saini R, Dhillon MS, Gill SS. Congenital subtalar dislocation-a case report. Foot 19; Kaufmann RA, Davidson R, McCarthy J. Bilateral congenital subtalar dislocation: A case report. Clin Orthop Relat Res 397). It is commonly seen in young men and the mechanism is inversion injury in plantar-flexed foot. Medial type dislocation is most commonly seen with incidence between 65% and 85% as stated in various studies. Pure ligamentous injuries have shown good prognosis, which when associated with fractures can affect the functional outcome. Methods: We conducted a prospective study from 1st January 2017 to 1st December 2020 including seven patients (5 males and 2 females) with closed medial subtalar dislocation with (1) or without fractures (6). In our study, closed reduction was performed in all cases. At final follow-up, functional outcome was evaluated using “AOFAS-AHFS score” and radiological assessment. Results: All seven patients had good functional outcome at final follow-up and found no difficulty in doing daily routine activities. Routine clinical and radiological assessments were also done at final follow-up. All patients had complete ROM at final follow-up. Conclusion: Closed medial subtalar dislocation without significant articular fractures has good outcome in terms of function if managed properly.
  Citation: Journal of Musculoskeletal Research
  PubDate: 2022-02-11T08:00:00Z
  DOI: 10.1142/S0218957722500051