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Balkan Journal of Dental Medicine
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This is an Open Access Journal

Open Access journal
ISSN (Print) 2335-0245 - ISSN (Online) 2335-0245
Published by Sciendo

[370 journals]

Three Dimensional Evaluation of Marginal Microleakage at the Adhesive
Interface between Different Fissure Sealants and Enamel: Micro-CT Analysis
- Abstract: SummaryBackground/Aim: Sealing ability and adhesion to enamel of fissure sealants are quite critical in prevention of dental caries. The objective of the present study was to assess the marginal microleakage of different material-based pit and fissures with non-invasive and invasive techniques by using the Micro-CT method.Material and Methods: 30 extracted human permanent molars were randomly assigned to three sealant groups (n=10) as resin-based ClinPro, giomer-based BeautiSealant, and glass ionomer-based Fuji IX-GP. Half of each group was randomly divided into two parts as non-invasive and invasive techniques. The volumetric analysis of marginal microleakage between the enamel-material interface was performed by using Micro-CT. The results were analyzed with Student’s t, One-Way ANOVA, Tukey and Games-Howell tests. Statistical significance level was considered as 0.05.Results: In non-invasive technique, Fuji IX-GP showed statistically significantly lower marginal microleakage values than Clinpro (p=0.022). Other comparisons were not significant (p>0.05). However, in invasive technique, microleakage values both of Fuji IX-GP and BeautiSealant were significantly lower than Clinpro (p<0.001, p<0.001). Besides, regardless of the sealant material, the invasive technique showed significantly superior results than non-invasive technique regarding marginal microleakage.Conclusions: Considering the clinical conditions, it was concluded that glass ionomer-based Fuji IX-GP and giomer-based BeautiSealant could be used as alternative to resin based sealants. Additionally, invasive technique (fissure preparation) can be recommended to reduce marginal microleakage.
  PubDate: Tue, 23 Nov 2021 00:00:00 GMT
Association between Self-Reported Bruxism, Peripartum Depression and
Myogenous Temporomandibular Disorders among Postpartum Women in Turkey
- Abstract: SummaryBackground/Aim: It is possible to find studies in the literature evaluating the relationship among self-reported bruxism, psychological factors, and myogenous temporomandibular disorder. In addition, the relationship between these issues has not yet been clarified. The objective of this study was to evaluate the association between peripartum depression, self-reported bruxism, and myogenous temporomandibular disorders among postpartum women in Turkey.Material and Methods: This study included 220 women, whom were asked about their bruxism behaviour during day and during sleep. Besides, all of them assessed with Short-Form Fonseca’s Anamnestic Index for myogenous temporomandibular disorder and the Edinburgh postnatal depression scale for peripartum depression.Results: The results showed that, self-reported bruxism was observed at a statistically significantly higher rate (94.3%) in peripartum depression group. 86.5% of the patients with self-reported bruxism had myogenous temporomandibular disorder (p<0.001). As a result, 80.0% of the patients with peripartum depression had myogenous temporomandibular disorder (p<0.001).Conclusions: In conclusion, a significant relationship has been found between peripartum depression and self-reported bruxism, self-reported bruxism and myogenous temporomandibular disorder, and peripartum depression and myogenous temporomandibular disorder. The present study is the first to evaluate the relationship between peripartum depression, self-reported bruxism, and myogenous temporomandibular disorder so it could be considered as a pilot attempt, and further studies using more representative samples are encouraged.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Periodontal Management during COVID-19 Pandemic: Mini Review
- Abstract: SummaryA few cases of pneumonia were reported by Wuhan Municipal Health Commission in Wuhan, Hubei Province, Republic of China and this mysterious pneumonia was recognized as novel coronavirus disease (COVID-19) in the course of time on 31 December 2019. Based on the literature knowledge, COVID-19 outbreak was came into existence through an animal-to-human transmission, then continued human-to-human diffusion. Especially dentists among the medical professionals are at high-risk group of SARS-CoV-2 virus contamination because of several routine dental procedures having the risk to convey the SARS-CoV-2 virus via droplets and close contact. In this mini review, it was aimed to give information about patient management during COVID-19 pandemic for dental practitioners, periodontologists and dental hygienists.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Characteristics and Prevalence of Anterior Buccal Mandibular Depression
Area in Cone Beam Computed Tomography Images
- Abstract: SummaryBackground/Aim: The purpose of this study was to assess the anterior buccal mandibular depressions (ABMD) prevalence and clinical characteristics at cone beam computed tomography images (CBCT).Material and Methods: 198 CBCT images with minimal depression between the mandibular molars were evaluated retrospectively. Presence and location of ABMD, its maximum depth, maximum width, cortical width, if any, alveolar crest width at maximum depth, the distance between maximum depth and alveolar crest apex and existing teeth in the relevant region were examined in cross-sectional views. Panoramic radiography of ABMD patients was evaluated for trabecular pattern and radiopacity to determine the area of interest. The possible lingual depression area on the maximum depth of ABMD slice was investigated and the same measurements for ABMD was performed. The presence of aperture / foramen in the ABMD area was also investigated.Results: The prevalence of ABMD was found as 43.43% where 82 cases were at bilateral side and 4 cases were only at left side. Lingual depression was observed in 20.7% right side and 30.2% left side of the ABMD cases. There was no statistically significant difference for maximum depth between different age groups. Most frequent location was observed in lateral and canine region (27.4%) followed by lateral-first premolar area (25.6%). Least frequent location was at canine-second premolar area (1.2%).Conclusions: ABMD is a lesser known area with a high prevalence observed on CBCT images. The detectability of the area on panoramic radiographs is limited. Clinicians should take into consideration ABMDs’ characteristics to avoid confusion with periapical pathologies. Failure to detect these areas before implant surgeries may cause complications. For this reason, it is important to be examined in detail for ABMD before surgery.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Effects of COVID-19 Pandemic on Turkish Private Practice Dentists’
Economic Well-Being
- Abstract: SummaryBackground/Aim: Coronavirus disease 2019 (COVID-19) is a global health concern. The COVID-19 pandemic has not only health implications but also important social, economic, and political consequences. Dental practices have currently cancelled elective procedures and restricted services to the provision of emergency dental care in order to prevent transmission of COVID-19, which has had serious financial implications. Although several reports about the economic consequences of the COVID-19 pandemic have been prepared, no study has analyzed the potential impact of a pandemic on the economy of private-practice dentists. In this context, the purpose of this study is to determine how the COVID-19 has shaped the economic behavior of Turkish private-practice dentists and study the underlying mechanisms.Material and Method: A total of 312 private practice dentists were included in the study. The researchers developed a closed-ended questionnaire that contained 10 questions and was divided into three parts. The first part captured demographic information (age, gender, and professional experience of dentists). The second part measured the economic effects of the pandemic. The third part explored the dentists’ economic behavior in the post-pandemic period.Results: Over half (52.6%) of the dentists stated that during the pandemic, they only cared for patients in emergency situations. Most (97.4%) of the dentists stated that the pandemic affected their economic situation negatively, and 66.7% of dentists stated that they could not meet their routine clinical expenses during the pandemic. In the post-pandemic period, 52.6% of dentists are considering increasing their treatment fees, and 19.2% of dentists are considering dismissing some of their employees for economic reasons.Conclusions: The significant limitation of clinical and surgical activities in private dental practice caused by the COVID-19 pandemic has had a very significant negative effect on private-practice dentists’ economic well-being.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Treatment of Gunshot-Related Mandibular Fracture with Splint-Guided
Reduction: Case Report
- Abstract: SummaryBackground/Aim: Gunshot injury-related mandibular fractures often have a complex pattern, characterized by comminution, bone loss, and soft-tissue avulsion. The management is difficult and varies between individual cases.Case Report: A 41-year-old male patient presented with marked swelling and ecchymosis in the left mandibular region. Intraorally, he had a deviated open bite on the left side. A unilateral comminuted mandibular fracture was diagnosed by panoramic radiograph and computed tomography. An acrylic dental splint-guided open reduction and internal fixation, including intermaxillary fixation through brackets and intermaxillary elastics, was planned. No complications were observed throughout the healing period, and healing at the fracture site was satisfactory. The occlusion returned to the preinjury position and was stable.Conclusions: This case report shows that successful functional and esthetic results can be achieved with a strict patient-specific treatment protocol for a comminuted mandibular fracture due to gunshot injury.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Canal Configuration of Maxillary Premolars in Cukurova Population: A CBCT
Analysis
- Abstract: SummaryBackground/Aim: Aim of this study was to evaluate the anatomy of root-canal systems and numbers of permanent maxillary premolars’ roots and canals, using cone beam computed tomography scans.Material and Methods: In this retrospective and observational study, maxillary right/left and first/second premolars of patients who were screened with cone beam computed tomography for various reasons in a Turkish dental school, were examined. Evaluated parameters were age, gender, canal configuration (Vertucci classification) and numbers of roots and canals. Chi-square test was used for statistical analysis. The level of significance was set at p<0.05.Results: A total of 1086 maxillary premolars including 555 first premolars and 531 second premolars were examined in 331 patients (186 female, 145 male). Presence of two roots was shown in 75% of first premolars. 76.3% of second premolars were found to have a single root. Most common canal configuration was type IV (73.2%) for first premolars and type II (32.4%) for second premolars. There was a significant relationship between gender and numbers of first and second premolars’ roots and canals.Conclusions: High heterogeneity of maxillary premolar root-canal system anatomy should be considered during endodontic treatment.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Sealing Efficiency of MTA, Accelerated MTA, Biodentine and RMGIC as
Retrograde Filling Materials
- Abstract: SummaryBackground/Aim: This in-vitro study evaluated the apical-sealing ability of MTA, MTA+10% CaCl2, Biodentine™ and RMGIC when used as retrograde material.Material and Methods: A total of 80 single-rooted bovine incisors were decoronated, instrumented, and divided into 4 groups according to retrograde material, as follows: Group 1: MTA (ProRoot MTA, Dentsply); Group 2: MTA (ProRoot MTA, Dentsply) + 10% CaCl2; Group 3: Biodentine (Biodentine®, Septodont); Group 4: RMGIC (Nova Glass -LC, Imicryl). Root surfaces were isolated with nail polish, and teeth were immersed in 2% methylene blue dye at 37°C for 48 h. The extent of dye penetration (mm) was measured under a stereomicroscope.Results: RMGIC had the highest mean-rank dye penetration score (MP=49.05), followed by MTA (MP=43.65), Biodentine (35.95) and MTA+CaCl2 (MP=33.35). The results of paired comparison tests found the mean microleakage value of MTA+10% CaCl2 and Biodentine (Group 3) to be significantly lower than that of RMGIC (respectively; p=0,020, p=0,019). No significant difference was found in the other group comparisons (p> 0.05).Conclusions: These results suggest that the addition of an accelerator to MTA may reduce microleakage following endodontic surgery. Biodentine can be used as an alternative to MTA on retrograde obturation.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Quality of Information about Accelerated Orthodontics on Instagram
- Abstract: SummaryBackground/Aim: Social media has become popular in recent years in dentistry. This study aims to evaluate the posts shared on Instagram related to accelerated orthodontic treatment.Material and Methods: The first 100 posts were selected for #acceleratedorthodontics and #speedbraces hashtags and analyzed. The type of posts, posts’ purpose, the source of posts, the number of likes and comments, the number of followers and followings of the users who uploaded the posts were recorded. Four posts in #speedbraces were irrelevant and the remaining 196 posts were evaluated.Results: The sources of the posts include 60 orthodontists, 20 dental pages, 9 dental clinics, 8 periodontologists, 3 surgeons in #acceleratedorthodontics hashtag. Also, 37 posts were preop-postopt, 34 of them were advertising, 14 of them were surgical information, 12 of them were professional information, and 3 of them were personal sharing in #acceleratedorthodontics hashtag. When the aims of the shares were evaluated, it was observed that 56 were for advertisement, 23 were for patient information, 7 were for entertainment, 6 were experience and 4 were preop-postop comparison in #speedbraces hashtag.Conclusions: The posts related to accelerated orthodontics on Instagram are insufficient in terms of the content. The patients should be guided to reach the correct sources of information by orthodontists.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Prevalence of Dental Number Anomalies Among A Group of Turkish Children
- Abstract: SummaryBackground/Aim: The study aimed to evaluate the prevalence and distribution of congenital dental number anomalies in the permanent dentition among a group of Turkish children in the Inner Aegean Region of Turkey.Material and Methods: A total of 5377 patients aged 7–9 who visited our clinic for the first time between September 2018 and September 2019 were investigated. The children were examined for tooth agenesis and supernumerary teeth using panoramic radiographs taken for various reasons and clinical records reviewed. Dental number anomalies were evaluated according to gender and localization. Descriptive and comparative statistical analyses were performed using the SPSS package software program Version 23.Results: For the study, the data of 1987 patients (947 female, 1040 male) were examined. The tooth agenesis was found in 109 patients (5.5%), the supernumerary teeth were found in 24 patients (1.2%). The prevalence of tooth agenesis was 5% in males, 6% in females. There was no statistical difference between genders (p>0.05). The distribution of tooth agenesis according to jaws and sides by gender was not statistically different (p>0.05). The most commonly missing teeth were mandibular left second premolar (37.6% of patients) and mandibular right second premolar (33% of patients). According to types of teeth and gender, molar tooth agenesis was seen more common in females than males (p<0.05), there was no significant difference in other types of teeth by gender. The prevalence of supernumerary teeth were 1.9% in males, 0.4% in females and the difference between genders was found to be statistically significant (p<0.05). All the supernumerary teeth were located in the anterior maxilla, and half of them were mesiodens.Conclusions: Early diagnosis and appropriate treatment choice are very important managing complications associated with congenital dental number anomalies and for differential diagnosis of characteristic syndromes.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Accidental Injection of EDTA Instead of Anesthesia Solution during Root
Canal Treatment: Case Report
- Abstract: SummaryBackground/Aim: Many irrigation solutions are used during root canal treatment. It is unacceptable to confuse irrigation solutions with anesthetic solution and inadvertently inject the patient. After such an error, local and systemic serious complications can be seen in the patient. The purpose of this case report is to show how careless use of etilendiamin tetraacedic acid (EDTA) can result in important complications, and offer some treatment methods for curing symptoms resulting from such complications.Case Report: A 17% EDTA solution, was inadvertently injected in the buccal mucosa of a 20-year-old male during routine root canal treatment. Severe pain, bleeding and mucosal swelling occurred shortly after the injection. Irrigation with saline was performed by sliding the mucoperiosteal flap at the injection site. Then the flap was sutured primary. At the control one week later, there were no areas of necrosis in the patient, but ecchymosis occurred. Decalcified areas were not detected in dental volumetric tomography examination.Conclusions: The dentists must apply the precautions of EDTA irrigation solution during the root canal treatment and manage the treatment of this clinical complication.
  PubDate: Wed, 03 Nov 2021 00:00:00 GMT
Application of Bio-Resorbable Membranes in Preventing Complications of
Lower Jaw Surgery
- Abstract: SummaryBackground/Aim: Prevention of inflammation and alveolar bone atrophy is very important in oral surgery. The aim of this study was to compare the use of two osteoplastic bio-resorbable membranes in order to prevent inflammatory complications and atrophy of the alveolar part of the mandible after surgical interventions.Material and Methods: We examined 86 patients 45-70 years old who were classified into four groups. In group 1, there were 21 patients who had a “bio-resorbable membrane type 1 implanted. The group 2 consisted of 23 persons treated with bio-resorbable membrane type 2. Only the occurrence of inflammatory complications after the placement of these membranes was monitored. Group 3 included 20 persons treated with membrane type 1 and group 4 included 22 patients treated with membrane type 2 to prevent both inflammatory complications and atrophy of the alveolar part of the mandible. The level of atrophy of the alveolar bone after one year was determined by cone-beam computed tomography. The obtained data were statistically evaluated.Results: Six inflammatory complications (“dry socket”) have been identified in operated patients treated with a membrane type 1 (the first and the third groups). Only two “dry socket” occurred in patients treated with membrane type 2 (the second and fourth groups). Group 4 had significant advantages in the alveolar crest height 14.6 (11.2-22.3) and in its width 7.7 (5.1-10.2) both in relation to the indices of group 3 (11.1 (9.7-20.4) and 6.2 (4.2-9.0).Conclusions: The bio-resorbable membrane type 2 prevented inflammatory complications in the short postoperative period after surgical interventions, as well as, the atrophy of the mandible.
  PubDate: Mon, 11 Oct 2021 00:00:00 GMT
Occupational Stress among Dental Professionals
- Abstract: SummaryStress at the work place was declared by the World Health Organization as a worldwide epidemic. The stress caused by work appears when the balance between one’s own possibilities and the environment demands is disturbed, which leads to a poor mental state. The fact is that the majority of dentists find they are under constant stress, which is caused by the nature of dental work. Literature describes dentistry as an extremely stressful profession. The main stressors include the tendency toward technical perfection, the causation of pain in patients, the lack of patient cooperation during dental treatment, the failure to maintain the given appointments. Adequate education and preparation, even during dental studies, non-neglect of symptoms and difficulties at the work place, adequate and timely response to the identification of the cause and its elimination or balancing, have a key role in solving this great problem in modern dentistry.
  PubDate: Thu, 15 Jul 2021 00:00:00 GMT
Influence of Different Reline Materials and Processing Methods on Flexural
Strength of Denture Base Material
- Abstract: SummaryBackground/Aim: Relining is defined as the procedure used to resurface the tissue side of a denture with new base material, thus producing an accurate adaptation is provided at the denture foundation area. During mastication, relined dentures have to withstand masticatory forces to prevent fracture. The aim of this study was to evaluate the flexural strength of acrylic resin denture base relined with different methods and materials.Material and Methods: Fourteen experimental groups and one control group were determined to consider different reline materials and processing methods. Acrylic resin specimens were prepared with the dimensions of 65× 10× 1.5 mm and reline materials (1.5 mm thickness) were placed on acrylic resins. Reline material was not used in control group specimens. Flexural strength values of relined and control specimens were measured with three-point bending test at a speed of 5 mm/min. Data were analyzed with using one way Anova and Student t tests.Results: The highest flexural strength values were shown in control group (86.51±1.08 MPa). There were significant differences among relined specimens (p< 0.05). For the relined specimens, the highest flexural strength values were found in the relined specimens with denture base material (77.90±1.93 MPa), and the lowest values were found in relined with autopolymerize acrylic material (59.81±1.50 MPa).Conclusions: Relining of the heat cure denture base material significantly decreases the flexural strength for all processing methods and materials.
  PubDate: Thu, 15 Jul 2021 00:00:00 GMT
Evaluation of Antibiotic Prescribing Patterns in Paediatric Dental
Patients: Cross - Sectional Epidemiological Study
- Abstract: SummaryBackground/Aim: The purpose of this study was to investigate the antibiotic prescribing patterns for the treatment of paediatric oral infection, dental trauma and prophylaxis among dentists in Turkey.Material and Methods: A total of 206 paediatric dentists, including general dentists, paediatric dentists and specialist dentists, participated in this cross-sectional study. The questionnaire included questions about the number of paediatric patients treated and antibiotics prescribed, the most commonly prescribed antibiotic for oral infections and the clinical conditions under which antibiotics were prescribed. The participants’ ages, workplaces and professional experience were also evaluated.Results: The majority of the participants were paediatric dentists (45.1%) and general dentists (42.7%). For the management of dental infections, most dentists prescribed penicillin (94.7%). Their foremost prescription choices for the presence of an anaerobic infection were metronidazole (48.5%) and penicillin (32%). For dental trauma, the most common antibiotic-prescribed cases were avulsion and contaminated wounds, followed by alveolar fracture. Antibiotics were prescribed as a first choice for dental infections and dental infections of anaerobic origin, with no significant differences between professional experience or dental specialty in the dentists (p > 0.05). Practitioners belonging to Ministry of Health dental centres significantly differed from all other groups in preferring the antibiotic cephalosporin for dental infections of anaerobic origin.Conclusions: Adherence to published guidelines for antibiotic prescriptions for anaerobic dental infections and dental trauma was low. Clearer, more specific guidelines and increased post-graduate education could lead to a reduction in the negative consequences of this issue’s resultant over-prescribed antibiotics.
  PubDate: Thu, 15 Jul 2021 00:00:00 GMT
The Evaluation of Medical Conditions in Patients Admitted to the Oral
Diagnosis Clinic
- Abstract: SummaryBackground/Aim: The aim of this study is to set forth the current systemic diseases of the patients admitted to the oral diagnosis clinic of the Faculty of Dentistry Sütçü İmam University, and the prevalence of these diseases.Material and Methods: This study will be conducted by retrospective evaluation of anamneses in the tooth information management system of patients admitted to the oral diagnosis clinic of the Faculty of Dentistry, Sütçü İmam University for dental treatment. The anamneses taken from the patients before their treatments will be obtained from digital medium.Results: Out of 4077 patients included in the study, 2554 were female, and 1523 were male. Of them, 25.6% had systemic diseases. The mean age of the patients was 35.24%+12.3. It was found that cardiovascular diseases were more common than the other systemic diseases. The most common cardiovascular disease was found to be hypertension (7.5%), while the most common endocrine system disease was diabetes mellitus (7.5%).Conclusions: Dental practitioners must keep themselves up-to-date as they encounter patients with systemic diseases. They must pay attention while taking anamneses from patients. Therefore, they may apply medical consultation to prevent probable complications when necessary.
  PubDate: Thu, 15 Jul 2021 00:00:00 GMT
Comparison of Cyclic Fatigue Resistance of Heat-Treated Nickel-Titanium
Reciprocating Instruments at the Intracanal Temperature
- Abstract: SummaryBackground/Aim: The aim of the present study was to compare the cyclic fatigue resistance of NiTi files running with reciprocal motion and having different characteristics (RPC Blue, WOG, EndoArt Wise Reciproc Gold, EndoArt Wise Reciproc Blue) at the intracanal temperature (35°C) by using NaOCl irrigation solution.Material and Methods: Totally 60 WaveOne GOLD (Dentsply-Sirona, Ballaigues, Switzerland), Reciproc Blue (VDW, Munich, Germany), EndoArt Wise Reciproc Gold, and EndoArt Wise Blue (Inci Dental Productions Co, Istanbul, Turkey) (n= 15) files were used. Each of the rotary files were tested at the intracanal temperature (35°C) using a dynamic model in a stainless-steel artificial canal with an inner diameter of 1.5 mm, 60° angle of curvature, and 2mm radius of curvature until fracture occurred. The device automatically stopped at the moment of fracture and the number of cycles to the fracture was calculated as per second. The lengths of fractured parts were measured using a digital microcaliper. The One-Way Analysis of Variance (ANOVA) and Tukey’s post-hoc tests were used for intergroup comparisons.Results: In 2 mm Radius of curvature, the EndoArt Wise Reciproc Blue group had a significantly higher time to fracture followed by the EndoArt Wise Reciproc Gold, Resiproc Blue, WaveOne Gold. No significant difference was found between EndoArt Wise Reciproc Gold and Resiproc Blue groups (P>0.05). Among the groups, there was no statistically significant difference in the lengths of fractured parts of the instruments (P> 0.05).Conclusions: EndoArt Wise Reciproc Blue files exhibited significantly higher cyclic fatigue resistance compared with other files tested in a 2-mm radius of curvature and a 60° angle in an artificial canal at the intracanal temperature.
  PubDate: Thu, 15 Jul 2021 00:00:00 GMT
Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma-Treatment
Modalities
- Abstract: SummaryHead and neck squamous cell carcinoma (HNSCC) belongs to the most frequent cancer subtypes in the world. Mutations due to genetic and chromosomal instability, syndromes such as Fanconi anemia and the Bloom syndrome, environmental risk factors such as tobacco smoking, alcohol and human papillomavirus infection (HPV) subtypes 16,18,31,33,35,52,58 are implicated in its pathogenesis. The HNSCC belongs to the solid tumors of epithelial origin and consists of stromal, inflammatory, cancer cells and most importantly a fraction of them, the cancer stem cells (CSCs). The identification of the CSCs through their biomarkers such as CD44, CD10, CD166, CD133, CD271, ALDH, Oct4, Nanog, Sox2 and Bmi1, the maintenance of their subpopulation through epithelial to mesenchymal transition, the role of HPV infection regarding their prognosis and of their microenvironment regarding their resistance to therapy, all constitute key elements that must be taken thoroughly into consideration in order to develop an effective targeted therapy. There are already therapies in place targeting specific related biomarkers, important biochemical pathways and growth factors. The aim of this literature review is to illustrate the treatment modalities available against the cancer stem cells of head and neck squamous cell carcinoma.
  PubDate: Thu, 15 Jul 2021 00:00:00 GMT
Evaluation of Perceptions of Smile Esthetics by Dental Students
- Abstract: SummaryBackground/Aim: The aim of this study was to investigate in the esthetic perceptions of 2nd grade dental students before and after training.Material and Methods: A total of 16 photographs which contain golden ratio, buccal corridor, midline deviation, incisal embrasure, lip line, midline diastema, dark triangles and smile arc were shown to 78 dental students (33 male, 45 female). Immediately after the training about the smile esthetics, the same photos were shown again. The effect of gender on esthetic perception was also examined, in addition to assessing the effects of education on esthetic perception. Pearson Chi-square, Fisher’s Exact test and McNemar test were used in the analysis of the results.Results: According to the results of the analysis, it was found that the answers of the smile arc before and after the education were statistically significant (p< 0.05). Accordingly, the rate of correct answers of women is statistically higher than that of men. A statistically significant difference was found between the responses to the gingival appearance in the smile before and after the education (p< 0.05).Conclusions: Based on the limited results of this study, professional dental education may affect the esthetic evaluation of smile. There were differences in the esthetic perception of women and men.
  PubDate: Thu, 15 Jul 2021 00:00:00 GMT
Hemostatic and Histopathological Effects of Local Mineral Zeolite and
Tranexamic Acid in Experimental Femoral Artery Bleeding Model
- Abstract: SummaryBackground/Aim: This study aimed to evaluate the effect of local zeolite and tranexamic acid application on hemostasis duration and histopathological changes in the experimental bleeding model, created by puncturing femoral arteries in rats.Material and Methods: A total of 36 Sprague Dawley female rats weighing an average of 240 ± 20 g were used in the study. The three main study groups were the zeolite, zeolite+tranexamic acid, and control groups. Each group was sacrificed on the seventh and fourteenth days of the study, using subgroups for histopathological findings. After piercing the femoral artery of each rat, one gram of the material assigned to the group was applied to the bleeding site after which a 100-gram scale weight was placed on the site for 30 sec intervals, during which temperature was measured. The same sequence of procedures was repeated for the control group, using only standard compression. Statistical analysis was performed using IBM Statistical Package for Social Sciences (SPSS) 15 statistical software. Significance was evaluated at the level of p< 0.05.Results: The bleeding stop time of the control group was significantly longer than the zeolite and zeolite+tranexamic groups (p< 0.05). There was no statistically significant difference between the zeolite and zeolite+tranexamic groups’ bleeding stop times (p> 0.05) or between the mean wound temperatures of the control and zeolite+tranexamic acid groups when bleeding stopped (p> 0.05).Conclusions: The effectiveness of the zeolite group and zeolite+tranexamic acid mixture is more than the control group in ensuring bleeding control. Their efficacy has been clearly observed in providing hemostasis. In addition, it has been determined that zeolite tranexamic acid mixture causes less exothermic reaction than zeolite group. We believe that this new formula should be developed and used to guide new studies.
  PubDate: Thu, 15 Jul 2021 00:00:00 GMT