Subjects -> MEDICAL SCIENCES (Total: 8185 journals)
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HEMATOLOGY (160 journals)                     

Showing 1 - 151 of 151 Journals sorted alphabetically
Acta Angiologica     Open Access   (Followers: 2)
Acta Haematologica     Full-text available via subscription   (Followers: 23)
Acta Haematologica Polonica     Open Access  
Adipocyte     Open Access  
Advances in Hematology     Open Access   (Followers: 13)
Africa Sanguine     Full-text available via subscription  
American Journal of Hematology     Hybrid Journal   (Followers: 52)
Anemia     Open Access   (Followers: 6)
Annals of Hematology     Hybrid Journal   (Followers: 15)
Archives of Hematology Case Reports and Reviews     Open Access  
Arteriosclerosis, Thrombosis and Vascular Biology     Full-text available via subscription   (Followers: 29)
Artery Research     Hybrid Journal   (Followers: 4)
Artificial Cells, Nanomedicine and Biotechnology     Hybrid Journal   (Followers: 4)
ASAIO Journal     Hybrid Journal   (Followers: 2)
Best Practice & Research Clinical Haematology     Hybrid Journal   (Followers: 5)
Blood     Hybrid Journal   (Followers: 296)
Blood Advances     Open Access   (Followers: 7)
Blood and Lymphatic Cancer : Targets and Therapy     Open Access   (Followers: 7)
Blood Cancer Journal     Open Access   (Followers: 18)
Blood Cells, Molecules, and Diseases     Hybrid Journal   (Followers: 8)
Blood Coagulation & Fibrinolysis     Hybrid Journal   (Followers: 60)
Blood Pressure     Open Access  
Blood Pressure Monitoring     Hybrid Journal   (Followers: 1)
Blood Purification     Full-text available via subscription   (Followers: 6)
Blood Reviews     Hybrid Journal   (Followers: 26)
BMC Hematology     Open Access   (Followers: 7)
BMJ Open Diabetes Research & Care     Open Access   (Followers: 29)
Bone Marrow Transplantation     Hybrid Journal   (Followers: 17)
British Journal of Diabetes & Vascular Disease     Open Access   (Followers: 21)
British Journal of Haematology     Hybrid Journal   (Followers: 60)
British Journal of Primary Care Nursing - Cardiovascular Disease, Diabetes and Kidney Care     Full-text available via subscription   (Followers: 10)
Canadian Journal of Diabetes     Hybrid Journal   (Followers: 28)
Case Reports in Hematology     Open Access   (Followers: 10)
Clinical and Applied Thrombosis/Hemostasis     Open Access   (Followers: 32)
Clinical Diabetes     Full-text available via subscription   (Followers: 39)
Clinical Diabetes and Endocrinology     Open Access   (Followers: 20)
Clinical Lymphoma & Myeloma     Full-text available via subscription   (Followers: 2)
Clinical Lymphoma Myeloma and Leukemia     Hybrid Journal   (Followers: 5)
Clinical Medicine Insights : Blood Disorders     Open Access   (Followers: 1)
Conquest : The Official Journal of Diabetes Australia     Full-text available via subscription   (Followers: 3)
Current Angiogenesis     Hybrid Journal   (Followers: 1)
Current Diabetes Reports     Hybrid Journal   (Followers: 24)
Current Diabetes Reviews     Hybrid Journal   (Followers: 27)
Current Hematologic Malignancy Reports     Hybrid Journal   (Followers: 2)
Current Opinion in Hematology     Hybrid Journal   (Followers: 20)
Cytotherapy     Full-text available via subscription   (Followers: 2)
Der Diabetologe     Hybrid Journal   (Followers: 2)
Diabetes     Full-text available via subscription   (Followers: 410)
Diabetes aktuell     Hybrid Journal   (Followers: 3)
Diabetes and Vascular Disease Research     Hybrid Journal   (Followers: 20)
Diabetes Care     Full-text available via subscription   (Followers: 469)
Diabetes Case Reports     Open Access  
Diabetes Educator     Hybrid Journal   (Followers: 27)
Diabetes Management     Full-text available via subscription   (Followers: 15)
Diabetes Research and Clinical Practice     Hybrid Journal   (Followers: 70)
Diabetes Spectrum     Full-text available via subscription   (Followers: 16)
Diabetes Technology & Therapeutics     Hybrid Journal   (Followers: 50)
Diabetes Therapy     Open Access   (Followers: 23)
Diabetic Foot & Ankle     Open Access   (Followers: 10)
Diabetic Medicine     Hybrid Journal   (Followers: 147)
Diabetologia     Hybrid Journal   (Followers: 205)
Diabetologia Kliniczna     Hybrid Journal  
Diabetologie und Stoffwechsel     Hybrid Journal   (Followers: 2)
Egyptian Journal of Haematology     Open Access  
eJHaem     Open Access  
European Journal of Haematology     Hybrid Journal   (Followers: 16)
Experimental Hematology     Hybrid Journal   (Followers: 6)
Experimental Hematology & Oncology     Open Access   (Followers: 6)
Expert Review of Hematology     Hybrid Journal   (Followers: 5)
Fluids and Barriers of the CNS     Open Access   (Followers: 1)
Global Journal of Transfusion Medicine     Open Access   (Followers: 1)
Haematologica - the Hematology journal     Open Access   (Followers: 33)
Haemophilia     Hybrid Journal   (Followers: 66)
Hematologia     Full-text available via subscription   (Followers: 3)
Hematología     Open Access  
Hematology     Open Access   (Followers: 15)
Hematology Reports     Open Access   (Followers: 4)
Hematology, Transfusion and Cell Therapy     Open Access   (Followers: 2)
Hematology/Oncology and Stem Cell Therapy     Open Access   (Followers: 6)
Hemodialysis International     Hybrid Journal   (Followers: 3)
Hepatitis Monthly     Open Access   (Followers: 3)
Immunohematology : Journal of Blood Group Serology and Molecular Genetics     Hybrid Journal   (Followers: 1)
Indian Journal of Hematology and Blood Transfusion     Hybrid Journal   (Followers: 2)
Info Diabetologie     Full-text available via subscription   (Followers: 1)
InFo Hämatologie + Onkologie : Interdisziplinäre Fortbildung von Ärzten für Ärzte     Full-text available via subscription  
Integrated Blood Pressure Control     Open Access  
International Blood Research & Reviews     Open Access  
International Journal of Clinical Transfusion Medicine     Open Access   (Followers: 3)
International Journal of Diabetes in Developing Countries     Hybrid Journal   (Followers: 6)
International Journal of Diabetes Research     Open Access   (Followers: 8)
International Journal of Hematologic Oncology     Open Access   (Followers: 2)
International Journal of Hematology     Hybrid Journal   (Followers: 4)
International Journal of Hematology Research     Open Access   (Followers: 2)
International Journal of Hematology-Oncology and Stem Cell Research     Open Access   (Followers: 2)
International Journal of Laboratory Hematology     Hybrid Journal   (Followers: 25)
Iraqi Journal of Hematology     Open Access  
JMIR Diabetes     Open Access  
Journal of Blood Disorders & Transfusion     Open Access   (Followers: 3)
Journal of Applied Hematology     Open Access   (Followers: 2)
Journal of Blood Medicine     Open Access   (Followers: 1)
Journal of Cerebral Blood Flow & Metabolism     Hybrid Journal   (Followers: 3)
Journal of Diabetes     Open Access   (Followers: 20)
Journal of Diabetes and its Complications     Hybrid Journal   (Followers: 25)
Journal of Diabetes and Metabolic Disorders     Open Access   (Followers: 8)
Journal of Diabetes Investigation     Open Access   (Followers: 12)
Journal of Diabetes Mellitus     Open Access   (Followers: 5)
Journal of Diabetes Research     Open Access   (Followers: 13)
Journal of Diabetes Research     Open Access   (Followers: 9)
Journal of Hematological Malignancies     Open Access  
Journal of Hematology     Open Access   (Followers: 2)
Journal of Hematology and Transfusion Medicine     Open Access   (Followers: 1)
Journal of Hematopathology     Hybrid Journal   (Followers: 3)
Journal of Hypo & Hyperglycemia     Partially Free  
Journal of Pediatric Hematology/Oncology     Hybrid Journal   (Followers: 8)
Journal of Social Health and Diabetes     Open Access   (Followers: 1)
Journal of Thrombosis and Haemostasis     Hybrid Journal   (Followers: 81)
Journal of Thrombosis and Thrombolysis     Hybrid Journal   (Followers: 35)
Journal of Transfusion Medicine     Full-text available via subscription  
Kidney and Blood Pressure Research     Open Access   (Followers: 4)
Leukemia     Hybrid Journal   (Followers: 22)
Leukemia and Lymphoma     Hybrid Journal   (Followers: 12)
Leukemia Research     Hybrid Journal   (Followers: 8)
Leukemia Research Reports     Open Access   (Followers: 1)
Leukemia Supplements     Full-text available via subscription  
Mediterranean Journal of Hematology and Infectious Diseases     Open Access  
Nederlands Tijdschrift voor Diabetologie     Hybrid Journal  
Nutrition & Diabetes     Open Access   (Followers: 20)
Oncohematology     Open Access   (Followers: 1)
Open Diabetes Journal     Open Access  
Open Hematology Journal     Open Access   (Followers: 1)
Open Hypertension Journal     Open Access  
Open Journal of Blood Diseases     Open Access  
Pediatric Blood & Cancer     Hybrid Journal   (Followers: 8)
Pediatric Hematology Oncology Journal     Open Access   (Followers: 3)
Peritoneal Dialysis International     Hybrid Journal  
Platelets     Hybrid Journal   (Followers: 3)
Practical Diabetes     Hybrid Journal   (Followers: 7)
Primary Care Diabetes     Hybrid Journal   (Followers: 26)
Research & Reviews : Journal of Oncology and Hematology     Full-text available via subscription   (Followers: 1)
Research and Practice in Thrombosis and Haemostasis     Open Access   (Followers: 1)
Revista Cubana de Hematología, Inmunología y Hemoterapia     Open Access  
Seminars in Hematology     Hybrid Journal   (Followers: 12)
Seminars in Thrombosis and Hemostasis     Hybrid Journal   (Followers: 45)
Thalassemia Reports     Open Access   (Followers: 1)
The Lancet Haematology     Full-text available via subscription   (Followers: 38)
Therapeutic Advances in Hematology     Hybrid Journal  
Thrombosis & Haemostasis     Hybrid Journal   (Followers: 145)
Thrombosis Research     Hybrid Journal   (Followers: 47)
Transfusionsmedizin - Immunhämatologie, Hämotherapie, Immungenetik, Zelltherapie     Hybrid Journal  
Transplantation and Cellular Therapy     Hybrid Journal   (Followers: 13)
Veins and Lymphatics     Open Access   (Followers: 1)

           

Similar Journals
Journal Cover
International Blood Research & Reviews
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2321-7219
Published by Science-res Publishing Homepage  [5 journals]
  • Comparism of Microscopy and Molecular Diagnosis of Ehrlichia ruminantium
           in Cattles in Makurdi Benue Nigeria

    • Authors: Terese Simon Atsuwe, Victor Ugochukwu Obisike, Edidiong John Udo
      Pages: 1 - 5
      Abstract: Introduction: Makurdi, is the capital city of Benue State, the food basket of the Nigeria, the city challenged with Ehrlichia ruminantium of cattle  that are responsible for severe losses caused either by negative impact of ticks blood loss or blood related infections, damage to hides and others. Aim: This study was designed to identify and Characterize Ehrlichia ruminantium of Cattle within Makurdi Nigeria using microscopy and molecular techniques (PCR). Methodology: Blood sample were collected from a total of 432 cattle of both sexes and analyzed microscopically using thin blood film and DNA examination was done using polymerase chain reaction (PCR). Tick-borne pathogens were identified and characterized by PCR amplification using species specific primer of 16s rRNA for Ehrlichia. Data obtained were analyzed using chi square, t-test and P values at less than 0.05 were considered significantly different. Results: The result of comparison of prevalence of infection of haeomoparasite using microscopy and PCR revealed that, microscopy was not able to detect Ehrlichia while PCR yielded at percentage of 15%, Ehrlichia prevalence. The percentage of prevalence of haemoparasite was highly detected by PCR than microscopy and this was statistically significant (P < 0.05). Conclusion: Ehrlichia ruminantium in cattle have been seen to be prevalent in Makurdi metropolis and molecular method such as PCR can effectively diagnose the infection.
      PubDate: 2022-06-09
       
  • Serological Pattern of Hepatitis B Virus Infection and Risk Factors among
           Infected Individuals in Port Harcourt, Rivers State, Nigeria

    • Authors: Baribefe Banavule Daniel Koate, Teddy Charles Adias, Ebirien-Agana Samuel Bartimaeus, Zacchaeus Awortu Jeremiah
      Pages: 6 - 21
      Abstract: Hepatitis B virus infection is a serious global public health challenge that affects more than two billion people worldwide. This study aimed to evaluate the serological pattern of HBV infection in HBV infected patients in Port Harcourt, Nigeria. The main aim of this study was to evaluate the serological pattern of hepatitis B infection in Port Harcourt, Nigeria. This was a comparative cross sectional study carried out on 260 hepatitis B patients and blood donors attending hepatitis B clinics, and blood banks in Rivers State University Teaching Hospital, Port Harcourt, Military Hospital, Port Harcourt, and University of Port Harcourt Teaching Hospital, Choba. The study involved the use of hepatitis B panel assay, measurement of prevalence of hepatitis B virus infection in Port Harcourt, assessment of hepatitis B serological markers in all subjects, determination of the presence and prevalence of occult HBV among participants. HBV 5-parameter (panel) Rapid Test kit was used to assess HBV serological markers. Standard operation procedure, good laboratory practice, External/Internal Quality Control were used accordingly and Quality Assurance ensued. 84.2% participants were males, 15.8% females aged between 19 and 65 years, Mean ±SD age 30.57±9.70 years, Participants from 20 states, South-South, South-East, and other Geo-political Zones of Nigeria, resident in the cosmopolitan city of Port Harcourt were enrolled. Result obtained showed serological markers among test subjects as 77.3% HBsAg, 43.97% HBsAb, 48.94% HBcAg, 36.17% HBcAb, and 46.81% HBeAg.  Grouping of HBV panel assay result was HBV positive 1 (Occult HBV) 7.8% (n=11), HBV positive 2 73.76% (n=104), HBV positive 3 – (occult HBV post treatment) 14.18% (n=20), HBV positive 4 4.26% (n=6). All five serological markers of HBV in infected patients in PHC are evident in significant proportions indicating real infections at different stages of disease manifestation. Mass screening for HBV infection is recommended for our populace to check spread.
      PubDate: 2022-06-25
       
  • Current and Emerging Laboratory Techniques for Malaria Diagnosis

    • Authors: Clement Ugochukwu Nyenke, Evelyn Orevaoghene Onosakponome, Roseanne Adah Okafor
      Pages: 22 - 36
      Abstract: Effective diagnostic methods must continue to be developed due to the effects of malaria on world health. Malaria is an infectious disease spread by mosquitoes that affects both people and other animals. It is the product of Plasmodium parasites, which are transmitted through bites from infected female Anopheles mosquitoes. Other sporozoan species responsible for malaria infections include the sporozoan parasites Plasmodium falciparum, Plasmodium ovale, Plasmodium vivax, Plasmodium malaria, and Plasmodium knowlesi. Routine diagnosis of malaria is impeded in areas where the disease is endemic by technical and infrastructure issues with laboratories. Prompt and accurate diagnosis is essential since good disease management is one of the primary actions of the Global Malaria Control Strategy. Accurate malaria detection is also crucial in order to inform malaria control efforts through epidemiologic screening and surveillance, for research reasons to evaluate the effectiveness of antimalarial medications and vaccines, and for blood bank screening. This study's main goal is to show some of the new and effective ways to diagnose malaria that go beyond the gold standard, light microscopy, which has some problems.
      PubDate: 2022-07-22
       
  • Is Defibrotide Prophylaxis Effective on Graft Versus Host Disease in
           Patients with Allogeneic Stem Cell Transplantation'

    • Authors: İrfan Yavaşoğlu, Atakan Turgutkaya, Hilal Eroğlu Küçükdiler, Gürhan Kadıköylü, Gökhan Sargın, Ali Zahit Bolaman
      Pages: 37 - 41
      Abstract: Introduction: Sinusoidal obstruction syndrome (SOS) is one of the complications of allogeneic stem cell transplantation (allo-SCT). Defibrotide (DF) is used effectively in SOS prophylaxis and treatment. Graft versus host disease (GVHD) is a significant cause of morbidity and mortality in allo-SCT. Here, we retrospectively investigated the effect of DF on the development of GVHD in these patients. Methods: We evaluated 81 allo-transplanted patients due to various diagnoses (benign or malignant), retrospectively. Thirty-four patients used DF as prophylaxis while 47 patients did not receive it. Acute and chronic GVHD assessments were performed at +30/100th day and throughout the life of the patients, respectively. Results: Acute GVHD was more common with DF use (82% vs 61%). There was no statistical significance in terms of the effect on chronic GVHD. We observed that one patient in the non- DF group developed SOS. Conclusions: DF may be beneficial to prevent acute GVHD. However, we observed that GVHD and mortality were more common in patients using DF. This is probably due to the similarity of high-risk criteria between GVHD and SOS. We have not found a significant association between defibrotide use and the development of chronic GVHD.
      PubDate: 2022-07-30
       
  • Understanding Complement-mediated Nervous System aging in Order to Develop
           Neurodegenerative Therapeutics

    • Authors: Gabriel Pisani, Byron Baron
      Pages: 42 - 52
      Abstract: Aging is becoming one of the biggest burdens to the developed world, mainly due to it being linked to a variety of diseases from neurodegenerative disorders such as Alzheimer’s disease to cancer. It involves the dysregulation of virtually every biological process known, affecting every organ and tissue by distinct mechanisms, the nature of which is only now beginning to be truly understood. This is also true for memory loss, which is considered one of the most typical signs of old age. This is not surprising, given the still limited knowledge regarding how memories and thoughts are stored and utilised by the Central Nervous System (CNS). A potential hint, however, is the recent discovery that the complement system plays a role in synaptic pruning, which is essential for erasing unneeded memories. This is particularly intriguing given that the complement system is a branch of the innate immune system which has been documented as being overactive with aging. This review will thus cover what is currently known about the relationship between the immune system and aging and how the changes in the immune system with age affect the brain in an effort to direct further research. This topic has not been reviewed as a whole, which is why this paper aims to summarise the information on this topic whilst also elaborating on the gaps in research in order to develop potential therapies for neurodegeneration and immunosenescence.
      PubDate: 2022-08-02
       
  • Study the Impact of Cramming in Medical Students

    • Authors: Forman Erwin Siagian
      Pages: 53 - 64
      Abstract: Aim: To reveal pre- exam cramming among pre-clinical medical students, what drives this practice, failure due to cramming and the problems and difficulties related to the act of cramming. Discussion: Cramming is common practice among struggling medical students. The prevalence of cramming is like an iceberg phenomenon. The act of stacking too many information just the night before an exam probably authorize the perpetrator to remember some information in the short term period and enable them to take in enough information for the exam. Along with this practice also comes sleep deprivation, mental and emotional disturbances and even substance abuse in order to achieve good marks and passing the exam. Unfortunately for some experts, cramming is not considered as learning.  Procrastination and some other reason are believed to be the reason the culprit commits cramming. Conclusion: Cramming not only changes the behavior of the perpetrator, but also has an impact on his family, classmates, environment and future.
      PubDate: 2022-08-03
       
  • The Prevalence of Malaria in COVID-19 Patients among Blood Group
           Classification

    • Authors: Onosakponome; Evelyn Orevaoghene
      Pages: 65 - 72
      Abstract: Background: COVID‐19 is caused by SARS‐CoV‐2; it is considered a global tragedy that has astounded health care systems. Since the pandemic began, identifying the characteristics that might influence risk of infection and poor disease outcomes have been of paramount interest. Malaria is still a major global health burden particularly in the sub-Saharan Africa region with about 230 million cases annually. Blood group systems are genetically inherited features whose associations with some infectious diseases have long been debated. Aim: This observational study was aimed at evaluating the prevalence of malaria in covid-19 patients based on blood group in Rivers State Isolation COVID-19 centers located in Rivers state Nigeria. Methodology: 400 subjects participated and gave consent to be included in the study. Subjects were grouped ABO blood classification using commercially available anti-sera A, B. Microscopic method was used for the examination of malaria parasite and Giemsa staining technique. Results: Out of the 400 samples, 327 subjects were infected with malaria parasite while 73 were uninfected. Furthermore,91 subjects were blood group A,85 subjects were blood group B,10 subjects were blood group AB and 214 subjects were blood group O. Additionally, the number of subjects infected with malaria among blood group A, AB, B and O are 71, 69, 7 and 180 respectively. Also the distribution of covid-19 among blood group A, B, AB and O is 78.02%, 81.17%, 70.00%, and 84.11% respectively. Furthermore, the prevalence of malaria and COVID -19 infection based on blood A, B, AB and O appeared to be 14.28%, 9.41%, 0.00% and 16.82% respectively. Conclusion: This study has shown that most COVID-19 patients in Rivers state COVID-19 centers have blood groups O and A and had malaria co-infection. The prevalence of malaria with COVID-19 patients based on blood group was high amongst group O patient.
      PubDate: 2022-08-03
       
  • Evaluation of Effectiveness of Different Regimens of Centrifugation for a
           Single-spin Method of Pure Platelet-containing Plasma Preparation

    • Authors: Viktoria Petrushenko, Dmytro Grebeniuk, Halyna Nazarchuk
      Pages: 73 - 83
      Abstract: Aims: The aim of the study is to determine the optimal parameters of single centrifugation for the preparation of platelet-containing plasma (PCP) with maximum reduction of other cellular elements of the blood. Materials and Methods: 30 conditionally healthy persons aged 18 to 60 years (36.9±11.2 years) were included in the study. A total of 12 centrifugation modes were studied: 110g × 5 min, 110g × 10 min, 110g × 15 min, 140g × 5 min, 140g × 10 min, 140g × 15 min, 160g × 5 min, 160g × 10 min, 160g × 15 min, 190g × 5 min, 190g × 10 min, 190g × 15 min. To evaluate the effectiveness of different centrifugation modes, in addition to the number of basic cellular elements, such indicators as platelet capture efficiency, platelet enrichment factor, erythrocyte-reducing efficiencies and leukocyte-reducing efficiencies were studied. Results: When examining the volumes of the obtained plasma containing platelets, it was found that almost all centrifugation modes allow obtaining significantly different volumes of the investigated blood fraction from the others (p<0.001). For clarity, the regimens were sorted according to the volume of platelet-containing plasma obtained, from the smallest to the largest. There was a progressive decrease in the numerical values of the concentration of platelets, erythrocytes and leukocytes in plasma samples. Also there was a progressive decrease in the numerical values of the coefficient of platelet enrichment. Conclusions: With a single centrifugation for the preparation of plasma containing platelets, the most effective mode is 160g × 10 min, which allows achieving a platelet enrichment factor of about 1.71 at a platelet concentration of 483.6 ± 45.4 × 109/l, a platelet capture efficiency of 85, 7 ± 0.1% and reductions of erythrocytes and leukocytes 98.76 ± 0.09% and 98.46 ± 0.14%, respectively.
      PubDate: 2022-08-09
       
  • Prevalence and Clinical Aspects of Hemophilia in the Western Region of
           Cameroon

    • Authors: Romaric De Manfouo Tuono, Gildas Boris Kuitsouc Tazemda, Ernest Tambo, Omer Njajou
      Pages: 84 - 91
      Abstract: Introduction: Hemophilia is a constitutional defect in blood clotting related to a clotting factor deficiency. Its remains a major public health problem, mainly due to ignorance of the disease, limited screening capacities and access to treatment in sub-Saharan Africa and particularly in Cameroon. It causes heavy bleeding in the absence of adequate management. Few reports are available about the disease in countries with limited resources. This study assess the occurrence of hemophilia in the Western region of Cameroon and clinical aspects with the aim of raising public awareness of the disease. Methods: A cross-sectional and descriptive study was carried out over a period of 04 months in 5 departments of the Western region of Cameroon, in particular Mifi, Ndé, Bamboutos, Haut Nkam and Menoua. The individuals were selected in their houses on the basis of clinical arguments, i.e. bleeding from the gums, traumatic wounds, hematomas. The blood samples taken from the latter were analyzed in the hemostasis laboratory of the Regional Hospital of Bafoussam. The epidemiological characteristics of hemophiliacs identified and suspects hemophiliacs were analyzed. The results obtained were analysed using statistical software R version 4.1.1. Results: Out of 5995 people selected, 13 (0.22%) cases of hemophilia were identified, 09 confirmed cases and 04 new cases. The mean age of the patients was 14.85 years old (1.5-49). The disease was discovered mainly during circumcision in the months following birth (9/13, 69.23%), and by bleeding of the gums (9/13, 69.23%). Clinical signs were pain of the joints (46%), hematoma and swelling of the joints (38%). Platelets counts and prothrombin rate were normal in all. However, a prolonged Cephalin + Activator Time was found; it was corrected by supplying normal control plasma. Conclusion: Hemophilia is a pathology little known for the general public. For this, with the help of public authorithies, continuing education sessions must be set up to raise awareness among the population in order to limit the transmission of the disease and to eradicate this scourge which constitutes a real public health problem.
      PubDate: 2022-08-20
       
  • Hepatitis B Virus and Behavioural Risk among Blood Donors, Gabon

    • Authors: Denis; Maulot-Bangola, Christian, Mangala, Olivier, Rebienot Pellegrin, Joseph, Fokam, Thérèse, Nkoa
      Pages: 92 - 98
      Abstract: Background: In resource- limited setting, co-infection between HIV and hepatitis B virus (HBV) poses important public health considerations. This cross-sectional study was undertaken with the aim of determining HBV seroprevalence patterns in urban blood banks. Methods: A cross-sectional study was conducted at an urban blood bank setting. A total of 1610 blood donors were enrolled, and 283 consecutive plasma samples with unknown HBsAg status were selected for risks factors. HBV seroprevalence was based on the Chemiluminescence method (Cobas® e601, Roche). Potential risk factors associated with overt HBV infection were assessed by calculating the crude and adjusted odds ratio, 95% confidence intervalley (95% CI) and p values. Results: Of 1610 participants, overall rate seroprevalence of HBsAg was 5.5% (95% CI: 4.36%–6.58%) ranging from 0.06% (95% CI: 0-0.18) (HCV) to 0.12% (95% CI: 0-0.30) (Syphilis). Seroprevalence of infection increased in older age groups (20-39 years) but men had a statistically significant higher prevalence of overt HBV infection than women (P=0.0001). The multivariate model showed the following to be predictors of HBV infection: male gender (OR=2.5 (95% CI 1.14-5.58), P= 0.02), first-time donor status (OR = 11.06, (95% CI 5.34-22.9), P= 0.01) and residence outside of Libreville (OR = 2.52, 95% CI 1.09-5.83), P=0.03). Conclusion: HB and co-infection are n o t common in Gabon. Intermediate seroprevalence was associated with male gender, first-time donor status and residence outside of Libreville. HCV and HBV infection among the younger age groups are becoming an alarming issue. Prevention and control of HBV infection are needed to reduce HBV transmission.
      PubDate: 2022-08-25
       
  • Analysis of Donor Deferral in a Tertiary Health Institution in
           South-Western Nigeria

    • Authors: Temitope O. Olusanya, Abimbola Ogunlowo, Olusola T. Boyede, Uchenna S. Okafor, Adedolapo A. Onifade, Ayodele Fayiga, Mary F. Adaramola-Adepegba, Oluwasegun J. Adeniyi, Olalekan A. Kemiki, Ifeoluwa S. Abiodun
      Pages: 99 - 105
      Abstract: Aim: This study aimed at evaluating the deferral pattern among blood donors, in order to draw out lessons that will help canvass for a strengthened policy framework and encourage better outcomes in voluntary blood donation. Study Design: This was a retrospective study. Place and Duration of Study: All the data were sourced from the central database of donors, as recorded by the Haematology Department of Babcock University Teaching Hospital Ilisan-Remo, Ogun state, Nigeria.  The data used spanned through a period of 5 years, from 2017 to 2021. Methodology: A total of 7,362 voluntary and non-remunerated blood donors were included in this study. Their records were accessed and used for the study. Data were analysed using SPSS version 25. The level of statistical significance was set at P < 0.05. Results: In this study, half (50.2%) of the entire population of volunteers were between the ages of 18 and 30 years while only 3.7% of them were between 51 and 60 years of age. There were more male volunteers for blood donation compared to the females who only represented 10.8% of the population. 61% of the voluntary donors were accepted for blood donation while 39% were regarded as unfit and hence, deferred. The 3 main reasons for deferral in this study were inadequate hemoglobin (54.7% of deferral cases), unmatched blood group (30.9%) and transfusion transmissible infections (14.4%). Age and gender had a statistically significant (P < 0.05) relationship with the pattern of deferral of the volunteers. Conclusion: The high deferral rate observed in this study may reveal an urgent need for a community-based intervention and targeted efforts by necessary agencies to help improve the general health status of possible future voluntary blood donors.
      PubDate: 2022-08-26
       
  • Outcome of Haematological and Haemostatic Indices in Hospitalized Yellow
           Fever Patients at the Centre for Communicable Disease Control and Research
           (CCDCR) Federal Medical Centre, Asaba, Delta State, Nigeria

    • Authors: Sylvia Ifeoma Obu, Anthony Uchenna Asiodu, Victor Azubuike Osiatuma, Anastacia Okwudili Ojimba, Ngozichukwuka Andrew Oburo, Anthony Chukwuemeka Iyasele, Efe Erhinyaye Omoyibo, Chinyelu Ifeoma Emekekwue, Tochi Praise Nnanna, Justina Ifeoma Chukwumah, Samuel Uchenna Eluaka, Samuel Eno Edet, Queen Adesuwa Aigbokhaede, Ndudi Dibigbo-Ibeaji, Obianuju Nkemjika Jisieike, Ugoeze Francis Chinedu, Rosemary Odion Sadoh, Destiny Osarumwense Imade
      Pages: 106 - 115
      Abstract: Aim: To assess the outcome of haematological and haemostatic indices in hospitalized Yellow Fever Positive patients treated using levels of full blood count, platelet count and other red cell indices at the Centre for Communicable Disease and Research (CCDCR) Federal Medical Centre, Asaba, Delta State, Nigeria. Study Design:  Retrospective observational study. Place and Duration of Study: Centre for Communicable Disease Control and Research (CCDCR), Federal Medical Centre Asaba, Nigeria, between August and December 2020. Methodology: Descriptive data was collected from the records of fifty-six (56) patients aged 16 – 65 years who were hospitalized and treated at the CCDCR FMC Asaba, within the months of August to December, 2020 and 56 non-Yellow Fever subjects as control subjects. The patients’ samples were previously collected and analyzed for haematological parameters (neutrophil, eosinophil, basophil, lymphocytes, monocytes, platelet count, mean cell volume (MCV), mean cell haemoglobin (MCH) and mean cell haemoglobin concentration (MCHC), using an automated haematology analyzer. Data collected was analyzed using SPSS version 25 and P values less than .05 were considered statistically significant.  Results: There were higher levels of total white blood cell count, eosinophil and MCH in hospitalized yellow fever patients when compared with the control group (P < 0.05). On the other hand, there was a lower level in platelet count of hospitalized yellow fever patients when compared with non-yellow fever control subjects (P < 0.05).  There was no significant difference in other haematological indices assayed which appeared normal (P > 0.05). Conclusion: In conclusion, it can be inferred that yellow fever can be associated with several haematological derangements which this study has succeeded to lay bare. Understanding these characteristics aids in planning therapy, management of patients as well as monitoring outcome. 
      PubDate: 2022-09-06
       
  • Assessment of Infection Control Practices in Bolan Medical Complex and
           Sandeman Provincial Hospital of Quetta, Balochistan, Pakistan

    • Authors: Shumaila Nargus
      Pages: 116 - 123
      Abstract: Pakistan has a double burden of disease, with more than 40% of the population suffering from infectious diseases. Therefore, in order to lower the risk of dangerous, avoidable infections among patients and healthcare staff, effective hospital infection control programmes are crucial from both an economic and a therapeutic standpoint. The goal of the study was to locate any gaps in current infection control and preventive procedures. The two teaching hospitals Bolan Medical Complex and Sandeman Provincial Hospital in Quetta were the sites of this cross-sectional investigation. In the SAMPLE, 161 people participated. The Statistical Package for Social Sciences (SPSS) version 16.0 was used to analyse the data, which was gathered via data sheets and questionnaires. The findings revealed that the Infection Control Committee (ICC) member's view of health-associated infections (HAIs) was ultimately determined to be inconsequential (P=0.6), and their perception that the staff education level may be a contributing factor was also shown to be unimportant (P=0.1). The operation theatre, labour room, lab and blood bank, OPD, and wards at BMC were evaluated in reference to the steps taken there for infection control and prevention, and the results were observed 30, 25, 15, 14, and 15 accordingly. It was shown that the primary reason for the poor results was the negative perception of the ICC towards infection control and prevention. Therefore, it is necessary to alter how ICC is seen.
      PubDate: 2022-09-15
       
 
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