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HEMATOLOGY (160 journals)                     

Showing 1 - 151 of 151 Journals sorted alphabetically
Acta Angiologica     Open Access   (Followers: 2)
Acta Haematologica     Full-text available via subscription   (Followers: 23)
Acta Haematologica Polonica     Open Access  
Adipocyte     Open Access  
Advances in Hematology     Open Access   (Followers: 13)
Africa Sanguine     Full-text available via subscription  
American Journal of Hematology     Hybrid Journal   (Followers: 52)
Anemia     Open Access   (Followers: 6)
Annals of Hematology     Hybrid Journal   (Followers: 14)
Archives of Hematology Case Reports and Reviews     Open Access  
Arteriosclerosis, Thrombosis and Vascular Biology     Full-text available via subscription   (Followers: 29)
Artery Research     Hybrid Journal   (Followers: 4)
Artificial Cells, Nanomedicine and Biotechnology     Hybrid Journal   (Followers: 3)
ASAIO Journal     Hybrid Journal   (Followers: 2)
Best Practice & Research Clinical Haematology     Hybrid Journal   (Followers: 5)
Blood     Hybrid Journal   (Followers: 284)
Blood Advances     Open Access   (Followers: 6)
Blood and Lymphatic Cancer : Targets and Therapy     Open Access   (Followers: 7)
Blood Cancer Journal     Open Access   (Followers: 18)
Blood Cells, Molecules, and Diseases     Hybrid Journal   (Followers: 8)
Blood Coagulation & Fibrinolysis     Hybrid Journal   (Followers: 61)
Blood Pressure     Hybrid Journal  
Blood Pressure Monitoring     Hybrid Journal   (Followers: 1)
Blood Purification     Full-text available via subscription   (Followers: 6)
Blood Reviews     Hybrid Journal   (Followers: 26)
BMC Hematology     Open Access   (Followers: 7)
BMJ Open Diabetes Research & Care     Open Access   (Followers: 29)
Bone Marrow Transplantation     Hybrid Journal   (Followers: 17)
British Journal of Diabetes & Vascular Disease     Open Access   (Followers: 21)
British Journal of Haematology     Hybrid Journal   (Followers: 60)
British Journal of Primary Care Nursing - Cardiovascular Disease, Diabetes and Kidney Care     Full-text available via subscription   (Followers: 10)
Canadian Journal of Diabetes     Hybrid Journal   (Followers: 28)
Case Reports in Hematology     Open Access   (Followers: 10)
Clinical and Applied Thrombosis/Hemostasis     Open Access   (Followers: 32)
Clinical Diabetes     Full-text available via subscription   (Followers: 40)
Clinical Diabetes and Endocrinology     Open Access   (Followers: 20)
Clinical Lymphoma & Myeloma     Full-text available via subscription   (Followers: 2)
Clinical Lymphoma Myeloma and Leukemia     Hybrid Journal   (Followers: 5)
Clinical Medicine Insights : Blood Disorders     Open Access   (Followers: 1)
Conquest : The Official Journal of Diabetes Australia     Full-text available via subscription   (Followers: 4)
Current Angiogenesis     Hybrid Journal   (Followers: 1)
Current Diabetes Reports     Hybrid Journal   (Followers: 24)
Current Diabetes Reviews     Hybrid Journal   (Followers: 27)
Current Hematologic Malignancy Reports     Hybrid Journal   (Followers: 2)
Current Opinion in Hematology     Hybrid Journal   (Followers: 19)
Cytotherapy     Full-text available via subscription   (Followers: 2)
Der Diabetologe     Hybrid Journal   (Followers: 2)
Diabetes     Full-text available via subscription   (Followers: 392)
Diabetes aktuell     Hybrid Journal   (Followers: 3)
Diabetes and Vascular Disease Research     Hybrid Journal   (Followers: 20)
Diabetes Care     Full-text available via subscription   (Followers: 450)
Diabetes Case Reports     Open Access   (Followers: 1)
Diabetes Educator     Hybrid Journal   (Followers: 27)
Diabetes Management     Full-text available via subscription   (Followers: 16)
Diabetes Research and Clinical Practice     Hybrid Journal   (Followers: 72)
Diabetes Spectrum     Full-text available via subscription   (Followers: 17)
Diabetes Technology & Therapeutics     Hybrid Journal   (Followers: 50)
Diabetes Therapy     Open Access   (Followers: 23)
Diabetic Foot & Ankle     Open Access   (Followers: 10)
Diabetic Medicine     Hybrid Journal   (Followers: 126)
Diabetologia     Hybrid Journal   (Followers: 191)
Diabetologia Kliniczna     Hybrid Journal  
Diabetologie und Stoffwechsel     Hybrid Journal   (Followers: 2)
Egyptian Journal of Haematology     Open Access  
eJHaem     Open Access  
European Journal of Haematology     Hybrid Journal   (Followers: 16)
Experimental Hematology     Hybrid Journal   (Followers: 6)
Experimental Hematology & Oncology     Open Access   (Followers: 6)
Expert Review of Hematology     Hybrid Journal   (Followers: 5)
Fluids and Barriers of the CNS     Open Access   (Followers: 1)
Global Journal of Transfusion Medicine     Open Access   (Followers: 1)
Haematologica - the Hematology journal     Open Access   (Followers: 33)
Haemophilia     Hybrid Journal   (Followers: 66)
Hematologia     Full-text available via subscription   (Followers: 3)
Hematología     Open Access  
Hematology     Open Access   (Followers: 15)
Hematology Reports     Open Access   (Followers: 4)
Hematology, Transfusion and Cell Therapy     Open Access   (Followers: 2)
Hematology/Oncology and Stem Cell Therapy     Open Access   (Followers: 6)
Hemodialysis International     Hybrid Journal   (Followers: 3)
Hepatitis Monthly     Open Access   (Followers: 3)
Immunohematology : Journal of Blood Group Serology and Molecular Genetics     Hybrid Journal   (Followers: 1)
Indian Journal of Hematology and Blood Transfusion     Hybrid Journal   (Followers: 2)
Info Diabetologie     Full-text available via subscription   (Followers: 1)
InFo Hämatologie + Onkologie : Interdisziplinäre Fortbildung von Ärzten für Ärzte     Full-text available via subscription  
Integrated Blood Pressure Control     Open Access  
International Blood Research & Reviews     Open Access  
International Journal of Clinical Transfusion Medicine     Open Access   (Followers: 3)
International Journal of Diabetes in Developing Countries     Hybrid Journal   (Followers: 6)
International Journal of Diabetes Research     Open Access   (Followers: 8)
International Journal of Hematologic Oncology     Open Access   (Followers: 2)
International Journal of Hematology     Hybrid Journal   (Followers: 4)
International Journal of Hematology Research     Open Access   (Followers: 2)
International Journal of Hematology-Oncology and Stem Cell Research     Open Access   (Followers: 2)
International Journal of Laboratory Hematology     Hybrid Journal   (Followers: 25)
Iraqi Journal of Hematology     Open Access  
JMIR Diabetes     Open Access  
Journal of Blood Disorders & Transfusion     Open Access   (Followers: 3)
Journal of Applied Hematology     Open Access   (Followers: 2)
Journal of Blood Medicine     Open Access   (Followers: 1)
Journal of Cerebral Blood Flow & Metabolism     Hybrid Journal   (Followers: 3)
Journal of Diabetes     Hybrid Journal   (Followers: 20)
Journal of Diabetes and its Complications     Hybrid Journal   (Followers: 26)
Journal of Diabetes and Metabolic Disorders     Open Access   (Followers: 8)
Journal of Diabetes Investigation     Open Access   (Followers: 12)
Journal of Diabetes Mellitus     Open Access   (Followers: 6)
Journal of Diabetes Research     Open Access   (Followers: 13)
Journal of Diabetes Research     Open Access   (Followers: 9)
Journal of Hematological Malignancies     Open Access  
Journal of Hematology     Open Access   (Followers: 2)
Journal of Hematology and Transfusion Medicine     Open Access   (Followers: 1)
Journal of Hematopathology     Hybrid Journal   (Followers: 3)
Journal of Hypo & Hyperglycemia     Partially Free  
Journal of Pediatric Hematology/Oncology     Hybrid Journal   (Followers: 8)
Journal of Social Health and Diabetes     Open Access   (Followers: 1)
Journal of Thrombosis and Haemostasis     Hybrid Journal   (Followers: 81)
Journal of Thrombosis and Thrombolysis     Hybrid Journal   (Followers: 35)
Journal of Transfusion Medicine     Full-text available via subscription  
Kidney and Blood Pressure Research     Open Access   (Followers: 4)
Leukemia     Hybrid Journal   (Followers: 22)
Leukemia and Lymphoma     Hybrid Journal   (Followers: 12)
Leukemia Research     Hybrid Journal   (Followers: 8)
Leukemia Research Reports     Open Access   (Followers: 1)
Leukemia Supplements     Full-text available via subscription  
Mediterranean Journal of Hematology and Infectious Diseases     Open Access  
Nederlands Tijdschrift voor Diabetologie     Hybrid Journal  
Nutrition & Diabetes     Open Access   (Followers: 20)
Oncohematology     Open Access   (Followers: 1)
Open Diabetes Journal     Open Access  
Open Hematology Journal     Open Access   (Followers: 1)
Open Hypertension Journal     Open Access  
Open Journal of Blood Diseases     Open Access  
Pediatric Blood & Cancer     Hybrid Journal   (Followers: 8)
Pediatric Hematology Oncology Journal     Open Access   (Followers: 3)
Peritoneal Dialysis International     Hybrid Journal  
Platelets     Hybrid Journal   (Followers: 3)
Practical Diabetes     Hybrid Journal   (Followers: 7)
Primary Care Diabetes     Hybrid Journal   (Followers: 27)
Research & Reviews : Journal of Oncology and Hematology     Full-text available via subscription   (Followers: 1)
Research and Practice in Thrombosis and Haemostasis     Open Access   (Followers: 1)
Revista Cubana de Hematología, Inmunología y Hemoterapia     Open Access  
Seminars in Hematology     Hybrid Journal   (Followers: 12)
Seminars in Thrombosis and Hemostasis     Hybrid Journal   (Followers: 47)
Thalassemia Reports     Open Access   (Followers: 1)
The Lancet Haematology     Full-text available via subscription   (Followers: 38)
Therapeutic Advances in Hematology     Hybrid Journal  
Thrombosis & Haemostasis     Hybrid Journal   (Followers: 124)
Thrombosis Research     Hybrid Journal   (Followers: 49)
Transfusionsmedizin - Immunhämatologie, Hämotherapie, Immungenetik, Zelltherapie     Hybrid Journal  
Transplantation and Cellular Therapy     Hybrid Journal   (Followers: 13)
Veins and Lymphatics     Open Access   (Followers: 1)

           

Similar Journals
Journal Cover
Journal of Applied Hematology
Number of Followers: 2  

  This is an Open Access Journal Open Access journal
ISSN (Print) 1658-5127 - ISSN (Online) 2454-6976
Published by Medknow Publishers Homepage  [448 journals]
  • Delta beta thalassemia, a rare hemoglobin variant: An experience from
           nodal centre in North Indian state

    • Authors: Promil Jain, Nisha Marwah, Niti Dalal, Richa Pawar, Meenu Gill, Sanjay Kumar
      Pages: 1 - 4
      Abstract: Promil Jain, Nisha Marwah, Niti Dalal, Richa Pawar, Meenu Gill, Sanjay Kumar
      Journal of Applied Hematology 2022 13(1):1-4
      CONTEXT: Fetal hemoglobin (HbF) reduces to <1% few months after birth. However, it can persist beyond infancy into adult life in rare conditions such as delta-beta (δβ) thalassemia and hereditary persistence of HbF. δβ thalassemia is a relatively rare type of thalassemia due to decrease in both beta and delta globin chain production.AIMS: This study aims to assess the hematological and high-performance liquid chromatography (HPLC) findings in δβ thalassemia.SETTINGS AND DESIGN: Cross-sectional observational study.SUBJECTS AND METHODS: The study was conducted in department of Clinical Pathology, PGIMS, Rohtak. On screening of 1197 patients over a period of around 1 year, a total of 13 cases of δβ thalassemia were detected by HPLC.STATISTICAL ANALYSIS USED: Not done.RESULTS: The age of presentation ranged from 1 to 42 years with a mean age of 22.8 years. Eleven cases were diagnosed as heterozygous δβ thalassemia and two as homozygous δβ thalassemia.CONCLUSIONS: δβ thalassemia is an uncommon cause of elevated HbF. Clinical and hematological parameters should be carefully analyzed for accurate diagnosis.
      Citation: Journal of Applied Hematology 2022 13(1):1-4
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_198_20
      Issue No: Vol. 13, No. 1 (2022)
       
  • Hematopoietic stem cell transplantation in paroxysmal nocturnal
           hemoglobinuria: Experience from a tertiary care center

    • Authors: Duncan Khanikar, Sandip Shah, Akanksha Garg, Kinnari Patel, Kamlesh Shah, Aishwarya Raj, Harsha Panchal, Apurva Patel, Sonia Parikh
      Pages: 5 - 8
      Abstract: Duncan Khanikar, Sandip Shah, Akanksha Garg, Kinnari Patel, Kamlesh Shah, Aishwarya Raj, Harsha Panchal, Apurva Patel, Sonia Parikh
      Journal of Applied Hematology 2022 13(1):5-8
      BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematological disorder characterized by episodic intravascular hemolysis. Despite newer therapies such as eculizumab, hematopoietic stem cell transplantation (HSCT) remains the only curative therapy. MATERIALS AND METHODS: An observational analytical retrospective study was conducted comprising eight PNH patients who had undergone HSCT at our center. From January 2014 to December 2020, we performed HSCT in 8 PNH patients, 5 female and 3 male, with median age of 32 years (range: 15–38 years). RESULTS: Seven patients had pancytopenia, associated with marrow hypocellularity. One patient presented with a thrombotic episode. Seven had matched sibling donor (MSD) transplant and one underwent haploidentical transplant. The median time from diagnosis to transplant was 7 months (range: 1–38 months). All received reduced intensity conditioning (RIC): Flu-Bu-Cy-A TG for MSD transplants and Flu-A TG-Post Cy in haploidentical transplants. Median CD34+ stem cell dose was 5.5 × 106/kg (range 3.4–5.8 × 106/kg). All had successful engraftment. Acute graft versus host disease (GVHD) Grade I–III occurred in six patients. Chronic GVHD occurred in two patients. One patient succumbed to Grade III liver GVHD. Rest seven patients are alive till date and transfusion independent. The overall survival was 87.5% at a median of 26 months. CONCLUSIONS: HSCT is the only curative therapy for PNH. With the use of RIC, the outcomes of PNH patients can be improved. The incidence of GVHD is high with RIC regimens but can be managed with prompt immunosuppression.
      Citation: Journal of Applied Hematology 2022 13(1):5-8
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_15_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • Evaluation of pediatric anemia in rural population of Maharashtra, India

    • Authors: Debopriya Chatterjee, Swapnil A More, Sneha R Joshi
      Pages: 9 - 12
      Abstract: Debopriya Chatterjee, Swapnil A More, Sneha R Joshi
      Journal of Applied Hematology 2022 13(1):9-12
      INTRODUCTION: World Health Organization showed that the prevalence of anemia among children of 6–59 months was 42.6% globally in 2011 and 59% in India. Fourth National Family Health Survey, 2016, shows 58.6% of Indian children are anemic, of which 53.8% are in Maharashtra, especially among rural children.AIMS: The aim of the study was to study the morphologic and cytometric evaluation of anemia in pediatric population.MATERIAL AND METHODS: The study was conducted after obtaining approval from the ethics committee. All patients that came to outpatient department and inpatient department between 2016 and 2018, satisfying the inclusion criteria were included. Routine investigations performed were hemoglobin estimation, blood indices, and peripheral blood smear examination.RESULTS: The total number of pediatric patients that were found to be anemic was 400 (54.9%). Toddlers, aged 6 months to 6 years, were most anemic (48.0%). Moderate severity of anemia was seen most frequently (50.5%). Microcytic hypochromic anemia (67.0%), iron deficiency anemia was the most common cause seen (65.2%).CONCLUSION: The occurrence of anemia in children is essential to be constantly monitored to identify causes, formation of intervention strategies, and ensure already formed national programs are effective.
      Citation: Journal of Applied Hematology 2022 13(1):9-12
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_50_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • Health-related quality of life of adolescents with sickle cell disease on
           hydroxyurea: A case-control study

    • Authors: Hayfaa Mohammed Mones, Meaad Kadhum Hassan, Bahaa Abd Al Hussein Ahmed
      Pages: 13 - 21
      Abstract: Hayfaa Mohammed Mones, Meaad Kadhum Hassan, Bahaa Abd Al Hussein Ahmed
      Journal of Applied Hematology 2022 13(1):13-21
      BACKGROUND: Sickle cell disease (SCD) is a chronic multisystem disorder associated with acute and chronic complications that may negatively impact the quality of life (QoL). The study aimed to assess the health-related QoL (HRQoL) of patients with SCD on hydroxyurea (HU) and the factors affecting HRQoL domains.MATERIALS AND METHODS: This case-control study included 174 patients with SCD (12–18-year-old); 87 were on HU for at least 1 year and 87 were not receiving HU. It also included 174 healthy adolescents of the same age group. The HRQoL was assessed using the Short Form 36 Health Survey version 2 (SF-36v2). A multivariate linear regression analysis was performed to assess the independent effect of studied variables on HRQoL dimensions.RESULTS: Patients with SCD who were not on HU were found to have significantly lower SF-36 v2 scores (all domains) compared to those on HU and control group, P < 0.001. While patients on HU had significantly lower SF-36 v2 scores in physical functioning, role physical (RP), general health, and physical health component score only compared to the control group, P < 0.001. Multivariate linear regression analysis revealed significant associations between duration of HU therapy and RP (R2 = 0.208, P = 0.021) and mental health component score (R2 = 0.389, P = 0.047) and between hemoglobin levels with social functioning (R2 = 0.370, P = 0.023).CONCLUSIONS: HU has improved the HRQoL of SCD patients, in almost all domains, in addition to the improvement in many disease-related complications, mainly painful episodes. The positive impact of HU on HRQoL was significantly associated with the duration of therapy.
      Citation: Journal of Applied Hematology 2022 13(1):13-21
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_7_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • Relationship between genotype variants and the age of first acute splenic
           sequestration in patients with sickle cell disease in a tertiary center of
           Saudi Arabia: A retrospective study

    • Authors: Lobna Abdulaziz Baitalmal, Fawaz Abdulaziz Al Kasim, Eatidal Fathey Ghareeb, Fauzia Rehman Azmet, Parameaswari Parthasarathy Jaganathan
      Pages: 22 - 27
      Abstract: Lobna Abdulaziz Baitalmal, Fawaz Abdulaziz Al Kasim, Eatidal Fathey Ghareeb, Fauzia Rehman Azmet, Parameaswari Parthasarathy Jaganathan
      Journal of Applied Hematology 2022 13(1):22-27
      BACKGROUND: Acute splenic sequestration crisis (ASSC) is one of the earliest life-threatening complications of sickle cell disease (SCD). Here, we aimed to identify the relation between the age of the first splenic sequestration episode and SCD variants. Episodes of acute splenic sequestration before 1 year of age are associated with a higher risk of recurrence.METHODS: We carried out a retrospective chart review study from the medical charts of SCD patients ≤12 years admitted to the Department of Pediatric Hematology King Saud Medical City, Riyadh with the first episode of ASSC and no other complications from January 2014 to December 2019.RESULTS: We included 47 patients (46.8% males, 53.2% females) diagnosed with SCD and having experienced their first ASSC in this review. The mean age of the patients at which the first episode of splenic sequestration happened was 3.26 years. The genotype distribution in the population was 74.5% HBSS, 21.3% HBS β0 thalassemia, and 4.3% HBSβ+ thalassemia. The crisis precipitated with fever in 74.5% of patients. Treatment included programmed blood transfusion (46.2%), splenectomy (29.8%). The recurrence rate after the first episode of ASSC was 59.6%. The high rate of recurrence was mainly due to the early age of presentation and poor compliance with suggested treatment. The use of hydroxyurea in 19.1% of patients showed a decrease of recurrence of ASSSC by 66.6% of patients.CONCLUSION: The study concluded that the HBSS variant of SCD had the earliest presentation with the first episode of ASSC but the differences were numerical without any statistical difference. Earlier age of presentation is associated with a higher rate of recurrence, but the difference was numerical not statistically significant. Our study shows hydroxyurea decreased recurrent splenic sequestrations; further research would help in establishing its role
      Citation: Journal of Applied Hematology 2022 13(1):22-27
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_244_20
      Issue No: Vol. 13, No. 1 (2022)
       
  • Role of serum hepcidin and reticulocyte hemoglobin concentration in
           evaluation of anemia in ulcerative colitis patients

    • Authors: Samar Reda Ammar, Medhat A Ghazy, Maaly M Mabrouk, Amr M Gawaly
      Pages: 28 - 34
      Abstract: Samar Reda Ammar, Medhat A Ghazy, Maaly M Mabrouk, Amr M Gawaly
      Journal of Applied Hematology 2022 13(1):28-34
      CONTEXT: One of the most common extra-intestinal signs of ulcerative colitis (UC) disease is anemia, which has a significant influence on patients' quality of life.AIM: The aim was to evaluate the role of serum hepcidin and reticulocyte hemoglobin concentration (CHr) in the study of anemia in UC patients.SUBJECTS AND METHODS: We recruited 80 UC patients and 30 healthy individuals of matched age and sex as controls. Subjects were subdivided into three groups – Group I: 50 anemic UC patients, Group II: 30 nonanemic UC patients, and Group III: 30 healthy controls.RESULTS: CHr showed a statistically highly significant decline in Group I than Groups II and III. Serum hepcidin showed a significant difference between Groups I, II, and III. We reported a significant negative correlation between CHr and severity of UC and extension of UC and a significant positive correlation between CHr and hemoglobin level, mean corpuscular volume (MCV), serum ferritin, and transferrin saturation. While, serum hepcidin had a significant negative correlation with severity and extension of UC and a significant positive correlation with hemoglobin level, MCV, serum ferritin, transferrin saturation, and CHr.CONCLUSIONS: CHr had an excellent performance in prediction of iron-restricted anemia and was the test of best performance in prediction of iron-deficiency anemia ± ACD. Serum hepcidin had an excellent performance in prediction of ACD.
      Citation: Journal of Applied Hematology 2022 13(1):28-34
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_127_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • The prevalence of cumulative alloimmunization in patients with sickle cell
           disease at King Fahad University Hospital

    • Authors: Rabab Ahmad AlDawood
      Pages: 35 - 40
      Abstract: Rabab Ahmad AlDawood
      Journal of Applied Hematology 2022 13(1):35-40
      BACKGROUND: Sickle cell disease (SCD) is caused by a mutation in the beta-globin gene. Red blood cell (RBC) transfusion is considered the mainstay of management. On the other hand, it carries many side effects, of which alloimmunization is the most significant.AIMS AND OBJECTIVES: The aim of this study is to identify the prevalence of alloimmunization among SCD patients and its relation with other independent risk factors in order to provide recommendations for the care of SCD patients.MATERIALS AND METHODS: This is a retrospective cohort study conducted at King Fahad Hospital of the University in Al-Khobar from January 1, 2010, to December 31, 2018. Data were collected from both the QuadraMed electronic system and the blood bank transfusion cards. Data were analyzed using IBM SPSS (version 23.0, Chicago, IL, USA).RESULTS: One hundred and seven out of 556 SCD patients developed alloantibodies with a prevalence of (19.2%). Anti-E was the most identified alloantibody in 37 (34.6%) patients, followed by anti-K in 33 (30.8%) of the alloimmunized SCD patients. We found a clinically significant correlation between the alloimmunization and age and direct antiglobulin test positivity.CONCLUSION: Alloimmunization is a major complication among SCD patients. Moreover, most of the formed alloantibodies were directed toward the Rh and K antigens. All SCD patients should undergo extended RBC phenotyping at the earliest opportunity, including the following RBC antigens (C/c, E/e, K, Jka/Jkb, Fya/Fyb, M/N, and S/s) at a minimum either serologically or by genotyping.
      Citation: Journal of Applied Hematology 2022 13(1):35-40
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_122_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • Maternal and neonatal variables affecting CD34&#43; cell count in
           the umbilical cord blood

    • Authors: Satya Prakash, Ashish Jain, Deepak Pahwa, Jaswinder Kaur Kalra, Rattiram Sharma
      Pages: 41 - 46
      Abstract: Satya Prakash, Ashish Jain, Deepak Pahwa, Jaswinder Kaur Kalra, Rattiram Sharma
      Journal of Applied Hematology 2022 13(1):41-46
      INTRODUCTION: Ease of collection, ready availability and lower graft-versus-host disease compared to peripheral blood stem cell favored umbilical cord blood stem cell transplantation.AIM: To assess the maternal and neonatal predictor affecting total nucleated and CD34+ cell count in cord blood collections.METHOD: A total of 200 Cord blood units were collected under aseptic conditions. Volume reduction was made by 6% hydroxyethyl starch followed by upright centrifugation of cord blood units to obtain a cellular pellet. Differential cell counts were done through hematology analyzer, viability testing by trypan blue exclusion test and percentage CD34, and CD45 estimation by flow cytometry. Two samples were HBsAg positive and not included in the study.RESULT: Total CD34 positive cell counts were more in cord blood units collected from younger age mother. Higher birth weight of newborns yielded a larger volume of cord blood unit and higher absolute TNC and CD34+ cell counts. The placental weight was positively correlated with the volume of cord blood collected, birth weight of new born, and total nucleated cell count but no correlation was observed with absolute CD34+ cell counts. The gravida status, gestational age and method of delivery were not significant with total nucleated cell (TNC), mononuclear cell (MNC), and CD34+ counts. CONCLUSION: Maternal age, birth weight, placental weight, and volume of CBUs were the most important predictor of getting increased nucleated and CD34+ cells in cord blood. Moreover, CBUs collected from pre-term deliveries were shown to have an approximately equal absolute number of CD34+ cells.
      Citation: Journal of Applied Hematology 2022 13(1):41-46
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_68_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • Iron deficiency anemia in pregnancy: Subgroup analysis from Riyadh mother
           and baby multicenter cohort study (RAHMA)

    • Authors: Hayfaa A Wahabi, Samia Esmaeil, Hala Elmorshedy, Hanadi Bakhsh, Aalaa Abdelrahman, Amel Fayed
      Pages: 47 - 53
      Abstract: Hayfaa A Wahabi, Samia Esmaeil, Hala Elmorshedy, Hanadi Bakhsh, Aalaa Abdelrahman, Amel Fayed
      Journal of Applied Hematology 2022 13(1):47-53
      OBJECTIVES: The objective of the study was to estimate the prevalence and risk factors of anemia among pregnant women in Riyadh and to examine its association with adverse pregnancy outcomes.METHODS: This study is a subgroup analysis from Riyadh mother and baby multicenter cohort study. Participants were grouped into four groups according to hemoglobin level: nonanemic (≥11.0 g/100 ml), mild (10–10.9 g/100 ml), moderate (7.0–9.9 g/100 ml), and severe anemia (<7.0 g/100 ml). Regression analyses were conducted to extrapolate the predicted probability (PP) for pregnancy outcomes.RESULTS: Out of 10,600 participants, 3261 (30.76%) were anemic; 1729 (16.3%), 1520 (14.3%), and 12 (0.1%) had mild, moderate, and severe anemia, respectively. The odds of anemia was higher in younger mothers (odds ratio [OR] = 0.94, confidence interval [CI]: 0.91–0.94) and in primiparous (OR = 1.01, CI: 0.90–1.14), while attendants of antenatal care and those who received iron supplements were less likely to be anemic (OR = 0.93, CI: 0.82–1.06) and (OR = 0.92, CI: 0.77–1.09), respectively. There was a significant increase in the odds of lower APGAR with the decreased hemoglobin; an increment of maternal hemoglobin by 1 g/100 ml decreased the likelihood of APGAR scores <7 by 9% (OR = 0.91, CI: 0.83–0.99). The PP showed a decrease in preterm birth (PTB) rate from 8% (CI: 6%–9%) to 6.5% (CI: 5%–8%), low birth weight (LBW) rate from 12% (CI 10%–13%) to 11% (CI: 9%–12%), stillbirth rate from 1.3% (CI: 0.7%–2.1%) to 1.1% (CI: 0.7%–1.6%), and maternal admission to intensive care unit (ICU) from 0.8% (CI: 0.2%–1.5%) to 0.2% (CI: 0.06%–0.4%), with increase of maternal hemoglobin from 7 g/100 ml to 15 g/100 ml.CONCLUSION: More than a third of the pregnant women in Riyadh had mild-to-moderate anemia. The odds of anemia increased in primipara, younger mothers, and those without antenatal care or iron supplementation. PP showed that anemia is associated with low APGAR scores, LBW, PTB stillbirth, and maternal admission to ICU.
      Citation: Journal of Applied Hematology 2022 13(1):47-53
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_133_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • Leukocyte adhesion defects Type III: A rare association of primary
           immunodeficiency and platelet functional defect

    • Authors: Anand Prakash
      Pages: 54 - 56
      Abstract: Anand Prakash
      Journal of Applied Hematology 2022 13(1):54-56
      Leukocyte adhesion defect (LAD) Type III is an extremely rare disease, which presents with severe infections and a Glanzmann thrombasthenia-like bleeding phenotype. A 2-year-old male child with LAD Type III with recurrent mucosal bleeding and relatively few infections is presented to highlight this novel presentation. The rare association of primary immunodeficiency and platelet functional disease is described.
      Citation: Journal of Applied Hematology 2022 13(1):54-56
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_43_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • Linezolid-induced pancytopenia and hyponatremia

    • Authors: Satish Kumar, Narayan Dhakal, Vishal Mangal, Anil Menon
      Pages: 57 - 59
      Abstract: Satish Kumar, Narayan Dhakal, Vishal Mangal, Anil Menon
      Journal of Applied Hematology 2022 13(1):57-59
      Linezolid (LnZ) is an antibiotic that is effective against Gram-positive bacteria and vancomycin-resistant enterococcus. LnZ is notorious to cause adverse hematological effects, primarily thrombocytopenia; however, pancytopenia is an infrequent complication. Euvolemic hyponatremia is a very rare adverse effect in patients receiving LnZ for more than 2 weeks. Early identification of pancytopenia and hyponatremia due to LnZ can result in avoidance of unnecessary investigations with improved patient outcome. An 80-year-old male with no previous comorbidities was admitted with a fracture neck of the left femur. He was empirically prescribed tablet LnZ 600 mg twice daily by the orthopedics team for soft-tissue infection over the sacral area. He underwent surgery for the left femur's fracture neck and was continued on LnZ in the postoperative period. Two weeks after the surgery, he was noticed to have pancytopenia and hyponatremia. After a thorough evaluation, LnZ was suspected to be the cause of pancytopenia and euvolemic hyponatremia. After 2 weeks of withholding LnZ, his pancytopenia and hyponatremia resolved. Physicians should be aware of the rare adverse effects of LnZ and should identify the patients at risk before administrating the drug. Regular monitoring of hematological and biochemical parameters is mandatory if intended to continue the drug for a more extended period.
      Citation: Journal of Applied Hematology 2022 13(1):57-59
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_29_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • A rare clinical presentation of Hodgkin&#39;s disease

    • Authors: Prashanth Parameswaran, Dilip Harindran Vallathol, Narayanankutty Warrier, Sajna V Kutty
      Pages: 60 - 62
      Abstract: Prashanth Parameswaran, Dilip Harindran Vallathol, Narayanankutty Warrier, Sajna V Kutty
      Journal of Applied Hematology 2022 13(1):60-62
      Hodgkin's disease or Hodgkin's lymphoma (HL) is a hematolymphoid neoplasm of B-cell lineage that has unique histologic, immunophenotypic, and clinical features. The occurrence of hemophagocytic lymphohistiocytosis (HLH) and neurological symptoms is rare in this disease. We present a case report of a 40-year-old woman who presented to our outpatient department with HLH and cerebellar signs. On further investigations, she was found to have classical HL. Her clinical condition improved with one cycle chemotherapy and steroids and she is on follow-up. This case indicates that a strong index of clinical suspicion is key to diagnose HLH and neurological symptoms (probably paraneoplastic) in HL. The cornerstone of management is identifying and treating the underlying cause.
      Citation: Journal of Applied Hematology 2022 13(1):60-62
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_234_20
      Issue No: Vol. 13, No. 1 (2022)
       
  • Atypical morphology and aberrant immunophenotypic expression: A diagnostic
           dilemma in acute promyelocytic leukemia

    • Authors: Shipra Verma, Paresh Singhal, Sharanjit Singh, Satyaranjan Das
      Pages: 63 - 67
      Abstract: Shipra Verma, Paresh Singhal, Sharanjit Singh, Satyaranjan Das
      Journal of Applied Hematology 2022 13(1):63-67
      Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia, which is highly aggressive, yet the most curable. It is a medical emergency that requires a very high index of suspicion, as delay in the treatment could lead to fatality. The initial diagnosis is made on the basis of its typical clinical presentation, morphological and immunophenotypic features. However, definitive diagnosis rests on the cytogenetic study. We present one such interesting case of APL where the morphology as well as immunophenotypic features was quite deceiving, leading to a diagnostic dilemma.
      Citation: Journal of Applied Hematology 2022 13(1):63-67
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_42_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • Root cause analysis of a moderately large fibrinous coagulum in a thawed
           fresh frozen plasma bag: Discussing the lessons learnt

    • Authors: Manish Raturi, Reshma Nambiyar, Yashaswi Dhiman, Adityaveer Sahrawat
      Pages: 68 - 69
      Abstract: Manish Raturi, Reshma Nambiyar, Yashaswi Dhiman, Adityaveer Sahrawat
      Journal of Applied Hematology 2022 13(1):68-69

      Citation: Journal of Applied Hematology 2022 13(1):68-69
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_164_21
      Issue No: Vol. 13, No. 1 (2022)
       
  • Bone marrow aspiration using 18g lumbar puncture needle: Correspondence

    • Authors: Rujittika Mungmunpuntipantip, Si M Sai Tin, Viroj Wiwanitkit
      Pages: 70 - 70
      Abstract: Rujittika Mungmunpuntipantip, Si M Sai Tin, Viroj Wiwanitkit
      Journal of Applied Hematology 2022 13(1):70-70

      Citation: Journal of Applied Hematology 2022 13(1):70-70
      PubDate: Thu,28 Apr 2022
      DOI: 10.4103/joah.joah_178_21
      Issue No: Vol. 13, No. 1 (2022)
       
 
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