Subjects -> MEDICAL SCIENCES (Total: 8196 journals)
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HEMATOLOGY (160 journals)                     

Showing 1 - 151 of 151 Journals sorted alphabetically
Acta Angiologica     Open Access   (Followers: 2)
Acta Haematologica     Full-text available via subscription   (Followers: 23)
Acta Haematologica Polonica     Open Access  
Adipocyte     Open Access  
Advances in Hematology     Open Access   (Followers: 13)
Africa Sanguine     Full-text available via subscription  
American Journal of Hematology     Hybrid Journal   (Followers: 52)
Anemia     Open Access   (Followers: 6)
Annals of Hematology     Hybrid Journal   (Followers: 14)
Archives of Hematology Case Reports and Reviews     Open Access  
Arteriosclerosis, Thrombosis and Vascular Biology     Full-text available via subscription   (Followers: 29)
Artery Research     Hybrid Journal   (Followers: 4)
Artificial Cells, Nanomedicine and Biotechnology     Hybrid Journal   (Followers: 3)
ASAIO Journal     Hybrid Journal   (Followers: 2)
Best Practice & Research Clinical Haematology     Hybrid Journal   (Followers: 5)
Blood     Hybrid Journal   (Followers: 284)
Blood Advances     Open Access   (Followers: 6)
Blood and Lymphatic Cancer : Targets and Therapy     Open Access   (Followers: 7)
Blood Cancer Journal     Open Access   (Followers: 18)
Blood Cells, Molecules, and Diseases     Hybrid Journal   (Followers: 8)
Blood Coagulation & Fibrinolysis     Hybrid Journal   (Followers: 61)
Blood Pressure     Hybrid Journal  
Blood Pressure Monitoring     Hybrid Journal   (Followers: 1)
Blood Purification     Full-text available via subscription   (Followers: 6)
Blood Reviews     Hybrid Journal   (Followers: 26)
BMC Hematology     Open Access   (Followers: 7)
BMJ Open Diabetes Research & Care     Open Access   (Followers: 29)
Bone Marrow Transplantation     Hybrid Journal   (Followers: 17)
British Journal of Diabetes & Vascular Disease     Open Access   (Followers: 21)
British Journal of Haematology     Hybrid Journal   (Followers: 60)
British Journal of Primary Care Nursing - Cardiovascular Disease, Diabetes and Kidney Care     Full-text available via subscription   (Followers: 10)
Canadian Journal of Diabetes     Hybrid Journal   (Followers: 28)
Case Reports in Hematology     Open Access   (Followers: 10)
Clinical and Applied Thrombosis/Hemostasis     Open Access   (Followers: 32)
Clinical Diabetes     Full-text available via subscription   (Followers: 40)
Clinical Diabetes and Endocrinology     Open Access   (Followers: 20)
Clinical Lymphoma & Myeloma     Full-text available via subscription   (Followers: 2)
Clinical Lymphoma Myeloma and Leukemia     Hybrid Journal   (Followers: 5)
Clinical Medicine Insights : Blood Disorders     Open Access   (Followers: 1)
Conquest : The Official Journal of Diabetes Australia     Full-text available via subscription   (Followers: 4)
Current Angiogenesis     Hybrid Journal   (Followers: 1)
Current Diabetes Reports     Hybrid Journal   (Followers: 24)
Current Diabetes Reviews     Hybrid Journal   (Followers: 27)
Current Hematologic Malignancy Reports     Hybrid Journal   (Followers: 2)
Current Opinion in Hematology     Hybrid Journal   (Followers: 19)
Cytotherapy     Full-text available via subscription   (Followers: 2)
Der Diabetologe     Hybrid Journal   (Followers: 2)
Diabetes     Full-text available via subscription   (Followers: 392)
Diabetes aktuell     Hybrid Journal   (Followers: 3)
Diabetes and Vascular Disease Research     Hybrid Journal   (Followers: 20)
Diabetes Care     Full-text available via subscription   (Followers: 450)
Diabetes Case Reports     Open Access   (Followers: 1)
Diabetes Educator     Hybrid Journal   (Followers: 27)
Diabetes Management     Full-text available via subscription   (Followers: 16)
Diabetes Research and Clinical Practice     Hybrid Journal   (Followers: 72)
Diabetes Spectrum     Full-text available via subscription   (Followers: 17)
Diabetes Technology & Therapeutics     Hybrid Journal   (Followers: 50)
Diabetes Therapy     Open Access   (Followers: 23)
Diabetic Foot & Ankle     Open Access   (Followers: 10)
Diabetic Medicine     Hybrid Journal   (Followers: 126)
Diabetologia     Hybrid Journal   (Followers: 191)
Diabetologia Kliniczna     Hybrid Journal  
Diabetologie und Stoffwechsel     Hybrid Journal   (Followers: 2)
Egyptian Journal of Haematology     Open Access  
eJHaem     Open Access  
European Journal of Haematology     Hybrid Journal   (Followers: 16)
Experimental Hematology     Hybrid Journal   (Followers: 6)
Experimental Hematology & Oncology     Open Access   (Followers: 6)
Expert Review of Hematology     Hybrid Journal   (Followers: 5)
Fluids and Barriers of the CNS     Open Access   (Followers: 1)
Global Journal of Transfusion Medicine     Open Access   (Followers: 1)
Haematologica - the Hematology journal     Open Access   (Followers: 33)
Haemophilia     Hybrid Journal   (Followers: 66)
Hematologia     Full-text available via subscription   (Followers: 3)
Hematología     Open Access  
Hematology     Open Access   (Followers: 15)
Hematology Reports     Open Access   (Followers: 4)
Hematology, Transfusion and Cell Therapy     Open Access   (Followers: 2)
Hematology/Oncology and Stem Cell Therapy     Open Access   (Followers: 6)
Hemodialysis International     Hybrid Journal   (Followers: 3)
Hepatitis Monthly     Open Access   (Followers: 3)
Immunohematology : Journal of Blood Group Serology and Molecular Genetics     Hybrid Journal   (Followers: 1)
Indian Journal of Hematology and Blood Transfusion     Hybrid Journal   (Followers: 2)
Info Diabetologie     Full-text available via subscription   (Followers: 1)
InFo Hämatologie + Onkologie : Interdisziplinäre Fortbildung von Ärzten für Ärzte     Full-text available via subscription  
Integrated Blood Pressure Control     Open Access  
International Blood Research & Reviews     Open Access  
International Journal of Clinical Transfusion Medicine     Open Access   (Followers: 3)
International Journal of Diabetes in Developing Countries     Hybrid Journal   (Followers: 6)
International Journal of Diabetes Research     Open Access   (Followers: 8)
International Journal of Hematologic Oncology     Open Access   (Followers: 2)
International Journal of Hematology     Hybrid Journal   (Followers: 4)
International Journal of Hematology Research     Open Access   (Followers: 2)
International Journal of Hematology-Oncology and Stem Cell Research     Open Access   (Followers: 2)
International Journal of Laboratory Hematology     Hybrid Journal   (Followers: 25)
Iraqi Journal of Hematology     Open Access  
JMIR Diabetes     Open Access  
Journal of Blood Disorders & Transfusion     Open Access   (Followers: 3)
Journal of Applied Hematology     Open Access   (Followers: 2)
Journal of Blood Medicine     Open Access   (Followers: 1)
Journal of Cerebral Blood Flow & Metabolism     Hybrid Journal   (Followers: 3)
Journal of Diabetes     Hybrid Journal   (Followers: 20)
Journal of Diabetes and its Complications     Hybrid Journal   (Followers: 26)
Journal of Diabetes and Metabolic Disorders     Open Access   (Followers: 8)
Journal of Diabetes Investigation     Open Access   (Followers: 12)
Journal of Diabetes Mellitus     Open Access   (Followers: 6)
Journal of Diabetes Research     Open Access   (Followers: 13)
Journal of Diabetes Research     Open Access   (Followers: 9)
Journal of Hematological Malignancies     Open Access  
Journal of Hematology     Open Access   (Followers: 2)
Journal of Hematology and Transfusion Medicine     Open Access   (Followers: 1)
Journal of Hematopathology     Hybrid Journal   (Followers: 3)
Journal of Hypo & Hyperglycemia     Partially Free  
Journal of Pediatric Hematology/Oncology     Hybrid Journal   (Followers: 8)
Journal of Social Health and Diabetes     Open Access   (Followers: 1)
Journal of Thrombosis and Haemostasis     Hybrid Journal   (Followers: 81)
Journal of Thrombosis and Thrombolysis     Hybrid Journal   (Followers: 35)
Journal of Transfusion Medicine     Full-text available via subscription  
Kidney and Blood Pressure Research     Open Access   (Followers: 4)
Leukemia     Hybrid Journal   (Followers: 22)
Leukemia and Lymphoma     Hybrid Journal   (Followers: 12)
Leukemia Research     Hybrid Journal   (Followers: 8)
Leukemia Research Reports     Open Access   (Followers: 1)
Leukemia Supplements     Full-text available via subscription  
Mediterranean Journal of Hematology and Infectious Diseases     Open Access  
Nederlands Tijdschrift voor Diabetologie     Hybrid Journal  
Nutrition & Diabetes     Open Access   (Followers: 20)
Oncohematology     Open Access   (Followers: 1)
Open Diabetes Journal     Open Access  
Open Hematology Journal     Open Access   (Followers: 1)
Open Hypertension Journal     Open Access  
Open Journal of Blood Diseases     Open Access  
Pediatric Blood & Cancer     Hybrid Journal   (Followers: 8)
Pediatric Hematology Oncology Journal     Open Access   (Followers: 3)
Peritoneal Dialysis International     Hybrid Journal  
Platelets     Hybrid Journal   (Followers: 3)
Practical Diabetes     Hybrid Journal   (Followers: 7)
Primary Care Diabetes     Hybrid Journal   (Followers: 27)
Research & Reviews : Journal of Oncology and Hematology     Full-text available via subscription   (Followers: 1)
Research and Practice in Thrombosis and Haemostasis     Open Access   (Followers: 1)
Revista Cubana de Hematología, Inmunología y Hemoterapia     Open Access  
Seminars in Hematology     Hybrid Journal   (Followers: 12)
Seminars in Thrombosis and Hemostasis     Hybrid Journal   (Followers: 47)
Thalassemia Reports     Open Access   (Followers: 1)
The Lancet Haematology     Full-text available via subscription   (Followers: 38)
Therapeutic Advances in Hematology     Hybrid Journal  
Thrombosis & Haemostasis     Hybrid Journal   (Followers: 124)
Thrombosis Research     Hybrid Journal   (Followers: 49)
Transfusionsmedizin - Immunhämatologie, Hämotherapie, Immungenetik, Zelltherapie     Hybrid Journal  
Transplantation and Cellular Therapy     Hybrid Journal   (Followers: 13)
Veins and Lymphatics     Open Access   (Followers: 1)

           

Similar Journals
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Diabetologia Kliniczna
Journal Prestige (SJR): 0.101
Number of Followers: 0  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 2084-4441
Published by Via Medica Homepage  [41 journals]
  • Outcome Prediction and Severity of Corona Virus Disease (COVID-19) on the
           Basis of Clinical and Laboratory Parameters

    • Free pre-print version: Loading...

      Authors: Virendra C Patil; Suresh J. Bhosale, Ashok Kshirsagar, Harsha V. Patil, Sanjay S. Patil
      Abstract: Background: Laboratory parameters play a key role in triaging, predicting disease course, severity and may determine prognosis COVID-19 patients. Material and methods: Aim and Objectives: To study the relation of clinical and laboratory parameters (total WBC count, neutrophil: lymphocyte ratio, serum ferritin, serum D-dimer, serum LDH, CRP, ESR) with severity and outcome of Corona Virus Disease (COVID-19) confirmed by real-time RT-PCR. Sample size: It was a time-bound study conducted over 3 months (1st April to 30th June, 2020). A total of 206 patients will be included in this study satisfying the inclusion criteria. Study design: This was a prospective, observational and non-interventional study conducted on patients with laboratory-confirmed COVID-19 admitted in a tertiary care teaching hospital. Statistical Analysis: Data will be analyzed for mean, percentage, standard deviation, and chi-square test for quantitative data by using appropriate statistical tests using INSTAT software version 8.0 (trial version) and p-value < 0.05 will be considered statistically significant. Results: Total of 206 patients of both genders were included in the present study. Total 141 (68.44%) patients were males and 65 (31.55%) patients were females (Chi Sq. 56.07; DF:1; p < 0.001). Among all the groups according to the severity of illness, ‘D’ group was the most common group (n = 99; 45.06%). Age > 60 years (17.48%), obesity (13.11%), hypertension (10.19%), COPD (5.83%), and diabetes mellitus (5.83%) were the most frequent risk factors or comorbidities associated with COVID-19 disease. Many patients had multiple risk factors in the present study. The majority (3/4th) of the patients were in C and D group (moderate) with co-morbidities and about 1/4th were in the severe group. Total 5 (2.43%) patients with COVID-19 patients succumbed to death with an overall case fatality rate of 2.43%. The case fatality rate was significantly higher among the patients with risk factors or comorbidities (p = 0.0124). Late presentation, associated comorbidity, advancing age, High level of ferritin, D-dimer, CRP, PaO2/FiO2 ratio less than 100 at the time of admission were associated with mortality. The terminal event in patients who have succumbed was bradycardia followed by cardiorespiratory arrest. The cause of death was ARDS with bilateral extensive pneumonia. Conclusions: Late presentation, associated comorbidity like diabetes mellitus, advancing age, High level of ferritin, D-dimer, CRP, PaO2/FiO2 ratio less than 100 at the time of admission were associated with mortality. The terminal event in patients who have succumbed was bradycardia followed by cardiorespiratory arrest. The cause of death was ARDS with bilateral extensive pneumonia.
      PubDate: Wed, 20 Apr 2022 18:20:08 +020
       
  • Evaluation of the Relationship between Serum Copeptin Level and Diabetic
           Retinopathy in Patients with Type 2 Diabetes

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      Authors: Shima Heydari; Mohammad Ali Yaghoubi, Gholamhossein Yaghoobi, Bita Bijari, Shadieh Poorabbas Feizabadi, Amirhossein Sahebkar
      PubDate: Wed, 20 Apr 2022 15:49:59 +020
       
  • Frailty in Diabetic Subjects during COVID-19 and Its Association with
           HbA1c, Mean Platelet Volume and Monocyte/Lymphocyte Ratio

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      Authors: Burcin Meryem Atak Tel; Satilmis Bilgin, Ozge Kurtkulagi, Gizem Kahveci, Tuba Taslamacioglu Duman, Tugrul Sagdic, Gulali Aktas
      Abstract: Background: Frailty is associated with increased risk of hospitalization in diabetic patients. Both SARS-CoV-2 pandemic and type 2 diabetes mellitus contribute to the frailty. In this study we aimed to observe clinical and laboratory indices of the diabetic subjects during COVID-19 pandemic who were either frail or not according to Edmonton frail score. Material and methods: During the pandemic era, 100 consecutive patients with type 2 diabetes mellitus divided into two groups either as frail or non-frail according to the Edmonton Frail Scale scores. Laboratory and clinical features of the frail and non-frail subjects were compared. Results: Frail patients were older than the non-frail diabetics. Blood urea, serum creatinine, eGFR, plasma albumin, total cholesterol, triglyceride, HbA1c, mean platelet volume (MPV), and monocyte lymphocyte ratio (MLR) levels of the frail and non-frail groups were significantly different. Moreover, Edmonton frail score was significantly and positively correlated with blood urea, serum creatinine, MLR, MPV, HbA1c and inversely correlated with eGFR and plasma albumin levels. Conclusions: We think that HbA1c, MPV and MLR could be surrogate markers of frailty in diabetic elderly during COVID-19 outbreak. Strategies to keep them in normal range do not only improve diabetes control but also reduce the risk of frailty in this population.
      PubDate: Tue, 19 Apr 2022 17:12:42 +020
       
  • The Effect of Hydroalcoholic Seed Extract of Securigera Securidaca on the
           Hepatic Renin-Angiotensin System in the Streptozotocin-Induced Diabetic
           Animal Model

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      Authors: Bahar Kiani; Shahin Alizadeh-Fanalou, Fatemeh Khomari, Mohammad Babaei, Iraj Alipourfard, Ali Kalantari Hesari, Mohammad Najafi, Ali-Mohammad Sharifi, Elham Bahreini
      Abstract: Background: The aim of the study was to investigate the effect of hydroalcoholic seed extract of Securigera securidaca (S. securidaca) (HESS) on liver local reninangiotensin system (RAS) in streptozotocin-induced diabetic rats. Methods: Three groups of diabetic male Wistar rats were treated with different doses of HESS (100, 200, 400 mg/Kg-BW), and the results were compared with diabetic and healthy control groups. To test the effects of HESS on liver local RAS as well as its alternative pathway, the tissue levels of renin, angiotensin-converting enzyme (ACE), ACE2, angiotensin-II (Ang-II), and Ang-(1-7) were measured. The oxidative state of liver tissue was evaluated by biomarkers of malondialdehyde (MDA), total oxidant status (TOS), and total antioxidant status (TAS). Due to the association between local RAS activity and tissue inflammation, the production of interleukins (IL) IL-1, IL-6, tumor necrosis factor alfa (TNF-a), and IL-10 in the liver was assayed in the experimental group. Results: Dose-dependent effects of HESS showed that the highest dose of the extract had a reducing effect on the hepatic levels of local RAS components including angiotensinogen, ACE, and Ang-II. Surprisingly, despite the decrease in tissue level of ACE2, an increase in Ang-(1-7) tissue concentration was observed. Decreased local RAS activity through treatment with the highest dose of HESS was associated with decreased tissue levels of proinflammatory cytokines (IL-1, IL-6, TNF-a), and increased anti-inflammatory cytokine (IL-10). Most of the effects of the extract are attributed to its antioxidant properties. Conclusions: S. securidaca seed can be suggested as a suitable drug supplement to prevent hepatic complications of diabetes.
      PubDate: Thu, 03 Mar 2022 16:24:34 +010
       
  • Influence of Physical Activity, Mediterranean Diet, Smoking, and Different
           Sociodemographic Variables on the Prevalence of Diabesity

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      Authors: Pere Riutord Sbert; Bartomeu Riutord Fe, Neus Riutord Fe, Sebastiana Arroyo Bote, Ángel Arturo López González, José Ignacio Ramírez Manent
      Abstract: Background: Diabesity is a pathological entity that encompasses the presence of obesity and type 2 diabetes in the same individual and, as occurs with both entities, its prevalence is increasing in industrialized countries. The objective of this study is to determine the influence of healthy habits and sociodemographic variables on the occurrence of diabesity. Methods: Descriptive, cross-sectional study in 1457 Spanish workers in which the influence of healthy habits such as physical exercise determined with the International. Physical Activity Questionnaire (IPAQ), adherence to the Mediterranean diet, and tobacco consumption were assessed, as well as sociodemographic variables such as age, sex, and social class on the prevalence of diabesity. Results: The prevalence of diabesity determined with seven scales increased as the level of physical activity decreased and adherence to the Mediterranean diet decreased. In the multivariate analysis, the variables that most influenced the appearance of diabesity were, in order, age over 50 years, male sex, and low or moderate physical activity. High adherence to the Mediterranean diet also had an inverse influence on diabesity, although the results obtained were not always significant; while tobacco consumption, Mediterranean diet, and social class II-III had no influence on almost any scale. Conclusions: Age is the risk factor that most increases the risk of diabesity, followed by the male sex.
      PubDate: Tue, 15 Feb 2022 20:20:27 +010
       
  • Serum Long Non-Coding RNAs in Diabetic Kidney Disease

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      Authors: Talaat Abdel-Fattah Abdel-Aty; Mohammad Nader Mowafy, Eman Ahmad El-Attar, Mohamed Aly Hasab, Yaser Aly Ammar
      Abstract: Background: Diabetic kidney disease (DKD) afflicts almost 40% of type 2 diabetes mellitus (T2DM) patients and may progress to end-stage renal disease despite multifactorial management. Urinary albumin/creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) are not sufficiently sensitive or specific for early diagnosis or recognition of patients at higher risk of cardiorenal complications. Long non-coding RNAs (lncRNAs) emerged as key regulators of major DKD signaling pathways. Their potential role as novel biomarkers or therapeutic targets in DKD remains to be established. Methods: We studied 4 groups of 25 adults each. G1, 2, 3 had T2DM and normal, moderately-increased, and severely-increased UACR, respectively. G4 were healthy controls. Participants underwent clinical assessment and analysis of blood picture, fasting serum glucose, glycated hemoglobin, lipid profile, hepatic transaminases, albumin, urea, and creatinine. By real-time quantitative polymerase chain reaction, we assessed relative serum expression levels of the lncRNAs plasmacytoma variant translocation-1 gene (PVT1), metastasis-associated lung adenocarcinoma transcript-1 (MALAT1), and cancer susceptibility candid-2 gene (CASC2). Results: Serum PVT1 was significantly higher in diabetic patients compared with controls, and significantly higher in G2 compared with the other patients’ groups. Serum MALAT1 and CASC2 showed no statistically significant association with the occurrence of T2DM, DKD, or other major diabetic complications. Increased serum creatinine was the only significant predictor of increased UACR. Conclusions: Increased serum PVT1 is a reliable early biomarker of DKD progression. It may provide a plausible therapeutic approach. The involvement of MALAT1 and CASC2 in DKD pathogenesis is less established. Further large-scale prospective studies are warranted.
      PubDate: Wed, 02 Feb 2022 15:52:51 +010
       
  • Study of the Relationship between Serum Asprosin, Endothelial Dysfunction
           and Insulin Resistance

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      Authors: Kamel Hemida Rohoma; Aly Ahmed Abdellrahim, Reham Abdel Haleem Abo Elwafa, Mohamed Galal Moawad
      Abstract: Background: Until now, the relationship between asprosin and soluble E-selectin (sE-selectin) as well as the role of asprosin in diabetes are still unclear. This work aimed to assess the relationship between fasting serum asprosin and markers of endothelial dysfunction and metabolic parameters, namely, sE-selectin, fasting insulin, fasting plasma glucose (FPG), HOmeostatic Model Assesment – Insulin Resistance (HOMA-IR), fasting lipid profile, and glycated hemoglobin (HbA1c) among people with different spectra of glycemia including normal subjects, impaired glucose tolerance (IGR), and subjects with type 2 diabetes mellitus (T2DM). Methods: Ninety subjects were recruited and divided according to the American Diabetes Association (ADA) diagnostic criteria into three groups; subjects with type 2 diabetes mellitus (n = 30), subjects with impaired glucose resistance (n = 30), and control subjects (n = 30). All groups were subjected to thorough history taking, physical examination, and laboratory investigation, involving fasting asprosin, sE-selectin, and HOMA-IR. Results: The univariate analysis showed a significant positive correlation between asprosin and glycemic parameters, insulin resistance, obesity parameters, and endothelial dysfunction in the three groups. However, multivariate analysis showed that triglycerides and sE-selectin are the most independent factors affecting asprosin. Univariate analysis for parameters affecting sE-selectin showed that asprosin is significantly correlated with sE-selectin, and multivariate analysis revealed that asprosin was the most independent factor affecting sE-selectin. Conclusions: Our study showed a significant positive correlation between asprosin, glucose dysregulation, insulin resistance, and endothelial dysfunction.
      PubDate: Wed, 02 Feb 2022 10:30:29 +010
       
  • Correlation of Vitamin D3, Insulin-Like Growth Factor 1 and Insulin
           Resistance in Pre-Diabetes and Newly Diagnosed Type 2 Diabetes

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      Authors: Dhananjay Gupta; Manish Kumar, Anubhuti Chitkara, A. K. Varshney
      Abstract: Background: Vitamin D deficiency is implicated in the pathogenesis of diabetes mellitus, and more importantly, in the progression of 'pre-diabetes' to overt diabetes mellitus. Alterations in circulating insulin-like growth factor 1 (IGF-1) levels to defects in insulin secretion from beta cells. IGF-1 increases 1,25(OH)D level in vitro by stimulating 1α-hydroxylase expression. Interaction between vitamin D and the IGF-1 system provides an explanation of why hypovitaminosis D levels lead to Insulin resistance. This study aims to find the role of vitamin D and IGF-1 in pre-diabetic individuals and their role in the progression of pre-diabetes to clinically overt diabetes mellitus. Methods: The observational study was done in the Department of Medicine and Department of Biochemistry, ABVIMS & PGIMER, Dr. RML Hospital, New Delhi, after Ethical approval from the institutional review board (IRB). Ninety study participants were enrolled, which included 30 pre-diabetics, 30 newly diagnosed type-2 diabetics, and 30 healthy controls. Results: Vitamin D levels decreased as the insulin resistance (homeostatic model assessment for insulin resistance [HOMA-IR] score) increased and this negative correlation between vitamin D levels and HOMA-IR was significant in pre-diabetic (p = 0.001) and the newly diagnosed diabetics group (p = 0.011), but not in the controls group (p = 0.067). Whereas, vitamin D and IGF-1 levels showed a similar positive correlation when compared amongst the three groups. The positive association between vitamin D and IGF-1 was statistically significant (p = 0.0012). Conclusions: Thus, vitamin D and IGF-1 levels should be measured in all individuals with dysglycemia, whether pre-diabetic or overt type 2 diabetic. And, if vitamin D insufficiency/deficiency is found, it should be corrected adequately in these patients. Although, a large population-based study is needed for the same.
      PubDate: Fri, 28 Jan 2022 14:35:39 +010
       
  • A Study of Combined Oral Anti-Diabetic Drugs during Ramadan

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      Authors: Majid H Alabbood; Nassar T Alibrahim, Haider A Alidrisi, Ali H Alhamza, Ammar M Almomin, Ibrahim H Hussein
      Abstract: Background: The safety and efficacy of combination tablets of metformin plus sulfonylurea or plus dipeptidyl peptidase-4 inhibitors have not been studied previously. This study aimed to compare the efficacy and safety of Gliconorm versus Sitavia plus among patients with type 2 diabetes mellitus who fast Ramadan. Methods: This was an open-label study conducted from 1 May 2018 till 1 July 2018. People with type 2 diabetes mellitus who were drug-naïve or on metformin only, with HbA1c < 10 % were included. The participants were divided into two groups. The first group was given Gliconorm (glibenclamide 5 mg + metformin 1000 mg), while the second group was given Sitavia plus (sitagliptin 50 mg + metformin 1000 mg) imme-diately after Iftar. Glycated hemoglobin (HbA1c) was measured before and after Ramadan. Several home recordings of blood glucose were collected. In addition, patients were asked to report any hypoglycemic or severe hyperglycemic episodes. Results: A total of 34 participants (18 women) (19 in the first group and 15 in the second group) were involved the study. The mean age was 49.6 ± 9.3 years. HbA1c reduced from 8.7 % (72 mmol/mol) to 7.6 % (60 mmol/mol) and from 8.7% (72 mmol/mol) to 7.7 % (61 mmol/mol) in the first and second group, respectively (p < 0.0001). Only one patient in the first group experienced one episode of hypoglycemia and hyperglycemia. Conclusions: Both medications seem to be safe and effective during Ramadan fasting. 
      PubDate: Fri, 05 Mar 2021 15:07:53 +010
       
 
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