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Diabetes Management
Number of Followers: 15

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ISSN (Print) 1758-1907
Published by Future Medicine

[29 journals]

Development of a fully canine anti-canine CTLA4 monoclonal antibody for
comparative translational research in dogs with spontaneous tumors
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  Authors: Nicola J. Mason, Nicholas Chester, Ailian Xiong, Antonia Rotolo, Ying Wu, Sho Yoshimoto, Patrick Glassman, Gayathri Gulendran, Don L. Siegel
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-12-03T03:58:05Z
  DOI: 10.1080/19420862.2021.2004638
  Issue No: Vol. 13, No. 1 (2021)
Drug-like antibodies with high affinity, diversity and developability
directly from next-generation antibody libraries
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  Authors: Andre Azevedo Reis Teixeira, Michael Frank Erasmus, Sara D’Angelo, Leslie Naranjo, Fortunato Ferrara, Camila Leal-Lopes, Oliver Durrant, Cecile Galmiche, Aleardo Morelli, Anthony Scott-Tucker, Andrew Raymon Morton Bradbury
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-12-01T11:44:27Z
  DOI: 10.1080/19420862.2021.1980942
  Issue No: Vol. 13, No. 1 (2021)
Agonistic nanobodies and antibodies to human VISTA
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  Authors: Yu-Heng Vivian Ma, Amanda Sparkes, Ema Romão, Shrayasee Saha, Jean Gariépy
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-24T07:39:48Z
  DOI: 10.1080/19420862.2021.2003281
  Issue No: Vol. 13, No. 1 (2021)
Hydrogen-deuterium exchange mass spectrometry reveals three unique binding
responses of mAbs directed to the catalytic domain of hCAIX
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  Authors: Joey G. Sheff, John F. Kelly, Anna Robotham, Traian Sulea, Félix Malenfant, Denis L’Abbé, Mélanie Duchesne, Alex Pelletier, Jean Lefebvre, Andrea Acel, Marie Parat, Mylene Gosselin, Cunle Wu, Yves Fortin, Jason Baardsnes, Henk Van Faassen, Shannon Awrey, Shawn C. Chafe, Paul C. McDonald, Shoukat Dedhar, Anne E.G. Lenferink
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-11-23T10:34:08Z
  DOI: 10.1080/19420862.2021.1997072
  Issue No: Vol. 13, No. 1 (2021)
Isolation and characterization of monoclonal antibodies against human
carbonic anhydrase-IX
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  Authors: Anne E.G. Lenferink, Paul C. McDonald, Christiane Cantin, Suzanne Grothé, Mylene Gosselin, Jason Baardsnes, Myriam Banville, Paul Lachance, Alma Robert, Yuneivy Cepero-Donates, Stevo Radinovic, Patrick Salois, Marie Parat, Hafida Oamari, Annie Dulude, Mehul Patel, Martin Lafrance, Andrea Acel, Nathalie Bousquet-Gagnon, Denis L’Abbé, Alex Pelletier, Félix Malenfant, Maria Jaramillo, Maureen O’Connor-Mccourt, Cunle Wu, Yves Durocher, Mélanie Duchesne, Christine Gadoury, Anne Marcil, Yves Fortin, Beatrice Paul-Roc, Maurizio Acchione, Shawn C. Chafe, Oksana Nemirovsky, Joseph Lau, Francois Bénard, Shoukat Dedhar
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-22T07:21:50Z
  DOI: 10.1080/19420862.2021.1999194
  Issue No: Vol. 13, No. 1 (2021)
An efficient system for bioconjugation based on a widely applicable
engineered O-glycosylation tag
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  Authors: Thomas V. Murray, Kasia Kozakowska-McDonnell, Adam Tibbles, Annabel Taylor, Daniel Higazi, Emmanuel Rossy, Alessandra Rossi, Sivaneswary Genapathy, Giulia Tamburrino, Nicola Rath, Natalie Tigue, Vivian Lindo, Tristan Vaughan, Monika A. Papworth
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-16T09:33:11Z
  DOI: 10.1080/19420862.2021.1992068
  Issue No: Vol. 13, No. 1 (2021)
Current strategies for detecting functional convergence across B-cell
receptor repertoires
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  Authors: Matthew I. J. Raybould, Anthony R. Rees, Charlotte M. Deane
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-16T09:23:38Z
  DOI: 10.1080/19420862.2021.1996732
  Issue No: Vol. 13, No. 1 (2021)
Development of a robust and semi-automated two-step antibody purification
process
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  Authors: Xiaomin Yang, Richard Yuan, Christopher Garcia, Jessica Berry, Denisa Foster, Dongmei He, Gui-Feng Zhang, Bryan E. Jones
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-16T05:35:37Z
  DOI: 10.1080/19420862.2021.2000348
  Issue No: Vol. 13, No. 1 (2021)
Polyreactivity and polyspecificity in therapeutic antibody development:
risk factors for failure in preclinical and clinical development campaigns

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  Authors: Orla Cunningham, Martin Scott, Zhaohui Sunny Zhou, William J.J. Finlay
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-15T05:05:35Z
  DOI: 10.1080/19420862.2021.1999195
  Issue No: Vol. 13, No. 1 (2021)
The impact of immunogenicity on therapeutic antibody pharmacokinetics: A
preclinical evaluation of the effect of immune complex formation and
antibody effector function on clearance
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  Authors: Eugenia Opolka-Hoffmann, Gregor Jordan, Michael Otteneder, Robin Kieferle, Martin Lechmann, Gerhard Winter, Roland F. Staack
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-12T07:59:52Z
  DOI: 10.1080/19420862.2021.1995929
  Issue No: Vol. 13, No. 1 (2021)
Impact of IgG subclass on molecular properties of monoclonal antibodies
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  Authors: Yu Tang, Paul Cain, Victor Anguiano, James J. Shih, Qing Chai, Yiqing Feng
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-12T07:55:53Z
  DOI: 10.1080/19420862.2021.1993768
  Issue No: Vol. 13, No. 1 (2021)
Differences in human IgG1 and IgG4 S228P monoclonal antibodies viscosity
and self-interactions: Experimental assessment and computational
predictions of domain interactions
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  Authors: Pin-Kuang Lai, Gaurav Ghag, Yao Yu, Veronica Juan, Laurence Fayadat-Dilman, Bernhardt L. Trout
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-08T11:10:54Z
  DOI: 10.1080/19420862.2021.1991256
  Issue No: Vol. 13, No. 1 (2021)
Viro-antibody therapy: engineering oncolytic viruses for genetic delivery
of diverse antibody-based biotherapeutics
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  Authors: Roland E. Kontermann, Guy Ungerechts, Dirk M. Nettelbeck
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-08T10:24:15Z
  DOI: 10.1080/19420862.2021.1982447
  Issue No: Vol. 13, No. 1 (2021)
Identification of a CE-SDS shoulder peak as disulfide-linked fragments
from common CH2 cleavages in IgGs and IgG-like bispecific antibodies
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  Authors: Mingyan Cao, Yang Jiao, Conner Parthemore, Samuel Korman, Jiao Ma, Alan Hunter, Greg Kilby, Xiaoyu Chen
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-01T07:27:15Z
  DOI: 10.1080/19420862.2021.1981806
  Issue No: Vol. 13, No. 1 (2021)
Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for
the treatment of cancer
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  Authors: Hong Xiang, Abigael G. Chan, Ago Ahene, David I. Bellovin, Rong Deng, Amy W. Hsu, Ursula Jeffry, Servando Palencia, Janine Powers, James Zanghi, Helen Collins
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-11-01T07:20:28Z
  DOI: 10.1080/19420862.2021.1981202
  Issue No: Vol. 13, No. 1 (2021)
Effect of variable domain charge on in vitro and in vivo disposition of
monoclonal antibodies
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  Authors: Shufang Liu, Ashwni Verma, Hubert Kettenberger, Wolfgang F. Richter, Dhaval K. Shah
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-29T06:48:10Z
  DOI: 10.1080/19420862.2021.1993769
  Issue No: Vol. 13, No. 1 (2021)
Nonclinical safety evaluation, pharmacokinetics, and target engagement of
Lu AF82422, a monoclonal IgG1 antibody against alpha-synuclein in
development for treatment of synucleinopathies
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  Authors: Lone Fjord-Larsen, Annemette Thougaard, Karen Malene Wegener, Joan Christiansen, Frank Larsen, Lise Maj Schrøder-Hansen, Marianne Kaarde, Dorte Kornerup Ditlevsen
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-28T08:32:14Z
  DOI: 10.1080/19420862.2021.1994690
  Issue No: Vol. 13, No. 1 (2021)
Novel chimeric monoclonal antibodies that block fentanyl effects and alter
fentanyl biodistribution in mice
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  Authors: Bhupal Ban, Rodell C. Barrientos, Therese Oertel, Essie Komla, Connor Whalen, Megan Sopko, Yingjian You, Partha Banerjee, Agnieszka Sulima, Arthur E. Jacobson, Kenner C. Rice, Gary R. Matyas, Vidadi Yusibov
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-25T10:20:15Z
  DOI: 10.1080/19420862.2021.1991552
  Issue No: Vol. 13, No. 1 (2021)
Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig
receptor display neutralization activity and mucosal enrichment
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  Authors: Ian White, Ninkka Tamot, Rajitha Doddareddy, Jason Ho, Qun Jiao, Paul B. Harvilla, Tong-Yuan Yang, Brian Geist, M. Jack Borrok, Matthew D. Truppo, Rajkumar Ganesan, Partha Chowdhury, Adam Zwolak
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-25T10:15:54Z
  DOI: 10.1080/19420862.2021.1987180
  Issue No: Vol. 13, No. 1 (2021)
Fc gamma receptor IIIb binding of individual antibody proteoforms resolved
by affinity chromatography–mass spectrometry
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  Authors: Steffen Lippold, Alexander Knaupp, Arnoud H. de Ru, Rayman T. N. Tjokrodirijo, Peter A. van Veelen, Erwin van Puijenbroek, Steven W. de Taeye, Dietmar Reusch, Gestur Vidarsson, Manfred Wuhrer, Tilman Schlothauer, David Falck
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-22T03:41:00Z
  DOI: 10.1080/19420862.2021.1982847
  Issue No: Vol. 13, No. 1 (2021)
Antibody mix-and-read assays based on fluorescence intensity probes
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  Authors: Ujwal Patil, Atul Goyal, Binh Vu, Yanyun Liu, Vijay Maranholkar, Katerina Kourentzi, James M. Briggs, Richard C. Willson
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-18T09:35:24Z
  DOI: 10.1080/19420862.2021.1980178
  Issue No: Vol. 13, No. 1 (2021)
Structure-based charge calculations for predicting isoelectric point,
viscosity, clearance, and profiling antibody therapeutics
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  Authors: Nels Thorsteinson, John R. Gunn, Kenneth Kelly, Will Long, Paul Labute
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-10T05:49:45Z
  DOI: 10.1080/19420862.2021.1981805
  Issue No: Vol. 13, No. 1 (2021)
Quantification of natural abundance NMR data differentiates the solution
behavior of monoclonal antibodies and their fragments
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  Authors: David Ban, Cory T. Rice, Mark A. McCoy
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-06T03:43:48Z
  DOI: 10.1080/19420862.2021.1978132
  Issue No: Vol. 13, No. 1 (2021)
Antibody blockade of CD96 by distinct molecular mechanisms
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  Authors: Peter S. Lee, Bryant Chau, Ishita Barman, Christine Bee, Aarti Jashnani, Jason M. Hogan, Barbara Aguilar, Gavin Dollinger, Arvind Rajpal, Pavel Strop
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-01T11:45:50Z
  DOI: 10.1080/19420862.2021.1979800
  Issue No: Vol. 13, No. 1 (2021)
Selective depletion of radiolabeled HER2-specific antibody for contrast
improvement during PET
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  Authors: Priyanka Khare, Wei Sun, Sreevidhya Ramakrishnan, Guiyang Hao, Su-Tang Lo, Kien Nham, Xiankai Sun, Raimund J. Ober, E. Sally Ward, Rafal Swiercz
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-10-01T03:55:36Z
  DOI: 10.1080/19420862.2021.1976705
  Issue No: Vol. 13, No. 1 (2021)
Enhancing the multi-attribute method through an automated and
high-throughput sample preparation
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  Authors: Pongkwan Sitasuwan, Thomas W. Powers, Tiffany Medwid, Yuting Huang, Bradley Bare, L. Andrew Lee
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-09-29T05:20:31Z
  DOI: 10.1080/19420862.2021.1978131
  Issue No: Vol. 13, No. 1 (2021)
Versatile and rapid microfluidics-assisted antibody discovery
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  Authors: Ramona Gaa, Emmanuel Menang-Ndi, Shruti Pratapa, Christine Nguyen, Satyendra Kumar, Achim Doerner
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-09-29T02:12:13Z
  DOI: 10.1080/19420862.2021.1978130
  Issue No: Vol. 13, No. 1 (2021)
Allometric scaling of therapeutic monoclonal antibodies in preclinical and
clinical settings
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  Authors: Eva Germovsek, Ming Cheng, Craig Giragossian
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-09-17T06:48:08Z
  DOI: 10.1080/19420862.2021.1964935
  Issue No: Vol. 13, No. 1 (2021)
Ten years in the making: application of CrossMab technology for the
development of therapeutic bispecific antibodies and antibody fusion
proteins
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  Authors: Marlena Surowka, Wolfgang Schaefer, Christian Klein
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-09-07T06:36:32Z
  DOI: 10.1080/19420862.2021.1967714
  Issue No: Vol. 13, No. 1 (2021)
Characterizing and understanding the formation of cysteine conjugates and
other by-products in a random, lysine-linked antibody drug conjugate
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  Authors: Difei Qiu, Yande Huang, Naresh Chennamsetty, Scott A. Miller, Michael Hay
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-09-05T01:22:22Z
  DOI: 10.1080/19420862.2021.1974150
  Issue No: Vol. 13, No. 1 (2021)
Sensitive, homogeneous, and label-free protein-probe assay for antibody
aggregation and thermal stability studies
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  Authors: Salla Valtonen, Emmiliisa Vuorinen, Ville Eskonen, Morteza Malakoutikhah, Kari Kopra, Harri Härmä
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-08-30T08:00:27Z
  DOI: 10.1080/19420862.2021.1955810
  Issue No: Vol. 13, No. 1 (2021)
A non-clinical comparative study of IL-23 antibodies in psoriasis
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  Authors: Li Zhou, Yibing Wang, Qi Wan, Fei Wu, Jeffrey Barbon, Robert Dunstan, Stephen Gauld, Mark Konrad, Laura Leys, Richard McCarthy, Marian Namovic, Christine Nelson, Gary Overmeyer, Denise Perron, Zhi Su, Leyu Wang, Susan Westmoreland, Jun Zhang, Rui Zhu, Geertruida Veldman
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-08-30T04:33:43Z
  DOI: 10.1080/19420862.2021.1964420
  Issue No: Vol. 13, No. 1 (2021)
Correction
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  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-08-25T06:59:10Z
  DOI: 10.1080/19420862.2021.1966993
  Issue No: Vol. 13, No. 1 (2021)
Accurate determination of epitope for antibodies with unknown 3D
structures
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  Authors: Shifa Tahir, Thomas Bourquard, Astrid Musnier, Yann Jullian, Yannick Corde, Zakaria Omahdi, Laetitia Mathias, Eric Reiter, Pascale Crépieux, Gilles Bruneau, Anne Poupon
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-08-25T06:57:15Z
  DOI: 10.1080/19420862.2021.1961349
  Issue No: Vol. 13, No. 1 (2021)
Improved epitope resolution of the prefusion trimer-specific antibody AM14
bound to the RSV F glycoprotein
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  Authors: Wayne Harshbarger, Priyanka D. Abeyrathne, Sai Tian, Ying Huang, Sumana Chandramouli, Matthew James Bottomley, Enrico Malito
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-08-23T07:35:13Z
  DOI: 10.1080/19420862.2021.1955812
  Issue No: Vol. 13, No. 1 (2021)
Untargeted proteomics reveals upregulation of stress response pathways
during CHO-based monoclonal antibody manufacturing process leading to
disulfide bond reduction
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  Authors: Seo-Young Park, Susan Egan, Anthony J. Cura, Kathryn L. Aron, Xuankuo Xu, Mengyuan Zheng, Michael Borys, Sanchayita Ghose, Zhengjian Li, Kyongbum Lee
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-08-23T06:21:58Z
  DOI: 10.1080/19420862.2021.1963094
  Issue No: Vol. 13, No. 1 (2021)
An end-to-end automated platform process for high-throughput engineering
of next-generation multi-specific antibody therapeutics
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  Authors: Norbert Furtmann, Marion Schneider, Nadja Spindler, Bjoern Steinmann, Ziyu Li, Ingo Focken, Joachim Meyer, Dilyana Dimova, Katja Kroll, Wulf Dirk Leuschner, Audrey Debeaumont, Magali Mathieu, Christian Lange, Werner Dittrich, Jochen Kruip, Thorsten Schmidt, Joerg Birkenfeld
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-08-12T02:53:58Z
  DOI: 10.1080/19420862.2021.1955433
  Issue No: Vol. 13, No. 1 (2021)
Host cell protein profiling of commercial therapeutic protein drugs as a
benchmark for monoclonal antibody-based therapeutic protein development
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  Authors: Rosalynn Molden, Mengqi Hu, Sook Yen E, Diana Saggese, James Reilly, John Mattila, Haibo Qiu, Gang Chen, Hanne Bak, Ning Li
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-08-07T07:04:44Z
  DOI: 10.1080/19420862.2021.1955811
  Issue No: Vol. 13, No. 1 (2021)
Development of potent and effective synthetic SARS-CoV-2 neutralizing
nanobodies
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  Authors: Maxwell A. Stefan, Yooli K. Light, Jennifer L. Schwedler, Peter R. McIlroy, Colleen M. Courtney, Edwin A. Saada, Christine E. Thatcher, Ashlee M. Phillips, Feliza A. Bourguet, Catherine M. Mageeney, Summer A. McCloy, Nicole M. Collette, Oscar A. Negrete, Joseph S. Schoeniger, Dina R. Weilhammer, Brooke Harmon
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-08-04T11:50:56Z
  DOI: 10.1080/19420862.2021.1958663
  Issue No: Vol. 13, No. 1 (2021)
Targeting and pharmacology of an anti-IL13Rα2 antibody and antibody-drug
conjugate in a melanoma xenograft model
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  Authors: Parul Gupta, Ziyue Karen Jiang, Bing Yang, Lisa Manzuk, Edward Rosfjord, Johnny Yao, Luanna Lemon, Kavon Noorbehesht, John David, Sujiet Puthenveetil, Jeffrey M. Casavant, Elwira Muszynska, Fengping Li, Mauricio Leal, Puja Sapra, Anand Giddabasappa
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-08-04T06:44:38Z
  DOI: 10.1080/19420862.2021.1958662
  Issue No: Vol. 13, No. 1 (2021)
Host cell protein detection gap risk mitigation: quantitative IAC-MS for
ELISA antibody reagent coverage determination
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  Authors: Daniel M. Waldera-Lupa, Yvonne Jasper, Pia Köhne, Ronja Schwichtenhövel, Heiner Falkenberg, Thomas Flad, Peter Happersberger, Bernd Reisinger, Alireza Dehghani, Roland Moussa, Thomas Waerner
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-08-04T06:41:11Z
  DOI: 10.1080/19420862.2021.1955432
  Issue No: Vol. 13, No. 1 (2021)
A matrix of structure-based designs yields improved VRC01-class antibodies
for HIV-1 therapy and prevention
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  Authors: Young D. Kwon, Mangaiarkarasi Asokan, Jason Gorman, Baoshan Zhang, Qingbo Liu, Mark K. Louder, Bob C. Lin, Krisha McKee, Amarendra Pegu, Raffaello Verardi, Eun Sung Yang, VRC Production Program, Kevin Carlton, Nicole A. Doria-Rose, Paolo Lusso, John R. Mascola, Peter D. Kwong
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-30T10:22:15Z
  DOI: 10.1080/19420862.2021.1946918
  Issue No: Vol. 13, No. 1 (2021)
Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell
engager targeting EGFR-positive tumors
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  Authors: Susanne Wingert, Uwe Reusch, Stefan Knackmuss, Michael Kluge, Michael Damrat, Jens Pahl, Ute Schniegler-Mattox, Thomas Mueller, Ivica Fucek, Kristina Ellwanger, Michael Tesar, Torsten Haneke, Joachim Koch, Martin Treder, Wolfgang Fischer, Erich Rajkovic
  Abstract: Volume 13, Issue 1, January-December 2021
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  PubDate: 2021-07-30T08:10:51Z
  DOI: 10.1080/19420862.2021.1950264
  Issue No: Vol. 13, No. 1 (2021)
Preclinical characterization of dostarlimab, a therapeutic anti-PD-1
antibody with potent activity to enhance immune function in in vitro
cellular assays and in vivo animal models
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  Authors: Sujatha Kumar, Srimoyee Ghosh, Geeta Sharma, Zebin Wang, Marilyn R. Kehry, Margaret H. Marino, Tamlyn Y. Neben, Sharon Lu, Shouqi Luo, Simon Roberts, Sridhar Ramaswamy, Hadi Danaee, David Jenkins
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-27T02:41:13Z
  DOI: 10.1080/19420862.2021.1954136
  Issue No: Vol. 13, No. 1 (2021)
Characterization of MW06, a human monoclonal antibody with
cross-neutralization activity against both SARS-CoV-2 and SARS-CoV
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  Authors: Wen Jiang, Junchao Wang, Shasha Jiao, Chenjian Gu, Wei Xu, Ben Chen, Rongjuan Wang, Huilin Chen, Youhua Xie, An Wang, Gang Li, Dadi Zeng, Jinchao Zhang, Min Zhang, Shuang Wang, Mingzhu Wang, Xun Gui
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-27T02:37:16Z
  DOI: 10.1080/19420862.2021.1953683
  Issue No: Vol. 13, No. 1 (2021)
Highly sensitive detection of antibody nonspecific interactions using flow
cytometry
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  Authors: Emily K. Makowski, Lina Wu, Alec A. Desai, Peter M. Tessier
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-27T02:35:26Z
  DOI: 10.1080/19420862.2021.1951426
  Issue No: Vol. 13, No. 1 (2021)
Discovery-stage identification of drug-like antibodies using emerging
experimental and computational methods
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  Authors: Emily K. Makowski, Lina Wu, Priyanka Gupta, Peter M. Tessier
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-27T02:31:18Z
  DOI: 10.1080/19420862.2021.1895540
  Issue No: Vol. 13, No. 1 (2021)
Targeting cancer with antibody-drug conjugates: Promises and challenges
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  Authors: Alexis Q. Dean, Shen Luo, Julianne D. Twomey, Baolin Zhang
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-22T12:03:11Z
  DOI: 10.1080/19420862.2021.1951427
  Issue No: Vol. 13, No. 1 (2021)
The therapeutic potential of sialylated Fc domains of human IgG
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  Authors: Richard J. Pleass
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-21T06:09:46Z
  DOI: 10.1080/19420862.2021.1953220
  Issue No: Vol. 13, No. 1 (2021)
Animal- versus in vitro-derived antibodies: avoiding the extremes
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  Authors: Andrew R.M. Bradbury, Stefan Dübel, Achim Knappik, Andreas Plückthun
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-20T06:39:05Z
  DOI: 10.1080/19420862.2021.1950265
  Issue No: Vol. 13, No. 1 (2021)
Challenges of non-clinical safety testing for biologics: A Report of the
9th BioSafe European Annual General Membership Meeting
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  Authors: Thomas Kissner, Guenter Blaich, Andreas Baumann, Sven Kronenberg, Adam Hey, Andrea Kiessling, Petra M. Schmitt, Wouter Driessen, Chantal Carrez, Daniel Kramer, Jennifer Fretland, Wolfgang F. Richter, Tobias Paehler, Ulrike Hopfer, Benno Rattel
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-09T01:03:00Z
  DOI: 10.1080/19420862.2021.1938796
  Issue No: Vol. 13, No. 1 (2021)
An integrated approach for characterizing immunogenic responses toward a
bispecific antibody
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  Authors: Sivan Cohen, Shan Chung, Christoph Spiess, Victor Lundin, Eric Stefanich, Steven T. Laing, Vanessa Clark, Jochen Brumm, Ying Zhou, Catherine Huang, Joyce Guerrero, Srividya Myneni, Rajbharan Yadav, Ketevan Siradze, Kun Peng
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-06T06:55:04Z
  DOI: 10.1080/19420862.2021.1944017
  Issue No: Vol. 13, No. 1 (2021)
Stability of a high-concentration monoclonal antibody solution produced by
liquid–liquid phase separation
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  Authors: Jack E. Bramham, Stephanie A. Davies, Adrian Podmore, Alexander P. Golovanov
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-06T06:51:07Z
  DOI: 10.1080/19420862.2021.1940666
  Issue No: Vol. 13, No. 1 (2021)
Correction
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  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-07-06T06:35:06Z
  DOI: 10.1080/19420862.2021.1935652
  Issue No: Vol. 13, No. 1 (2021)
A T cell redirection platform for co-targeting dual antigens on solid
tumors
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  Authors: Leonie Enderle, Karim H. Shalaby, Maryna Gorelik, Alexander Weiss, Levi L. Blazer, Marcin Paduch, Lia Cardarelli, Anthony Kossiakoff, Jarrett J. Adams, Sachdev S. Sidhu
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-06-30T10:58:43Z
  DOI: 10.1080/19420862.2021.1933690
  Issue No: Vol. 13, No. 1 (2021)
Identifying biophysical assays and in silico properties that enrich for
slow clearance in clinical-stage therapeutic antibodies
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  Authors: Boris Grinshpun, Nels Thorsteinson, Joao NS Pereira, Friedrich Rippmann, David Nannemann, Vanita D. Sood, Yves Fomekong Nanfack
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-06-12T06:50:11Z
  DOI: 10.1080/19420862.2021.1932230
  Issue No: Vol. 13, No. 1 (2021)
A human antibody of potent efficacy against SARS-CoV-2 in rhesus macaques
showed strong blocking activity to B.1.351
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  Authors: Chunyin Gu, Xiaodan Cao, Zongda Wang, Xue Hu, Yanfeng Yao, Yiwu Zhou, Peipei Liu, Xiaowu Liu, Ge Gao, Xiao Hu, Yecheng Zhang, Zhen Chen, Li Gao, Yun Peng, Fangfang Jia, Chao Shan, Li Yu, Kunpeng Liu, Nan Li, Weiwei Guo, Guoping Jiang, Juan Min, Jianjian Zhang, Lu Yang, Meng Shi, Tianquan Hou, Yanan Li, Weichen Liang, Guoqiao Lu, Congyi Yang, Yuting Wang, Kaiwen Xia, Zheng Xiao, Jianhua Xue, Xueyi Huang, Xin Chen, Haixia Ma, Donglin Song, Zhongzong Pan, Xueping Wang, Haibing Guo, Hong Liang, Zhiming Yuan, Wuxiang Guan, Su-Jun Deng
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-06-07T07:08:11Z
  DOI: 10.1080/19420862.2021.1930636
  Issue No: Vol. 13, No. 1 (2021)
501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in
vitro
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  Authors: Haolin Liu, Pengcheng Wei, Qianqian Zhang, Zhongzhou Chen, Katja Aviszus, Walter Downing, Shelley Peterson, Lyndon Reynoso, Gregory P. Downey, Stephen K. Frankel, John Kappler, Philippa Marrack, Gongyi Zhang
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-06-02T06:42:43Z
  DOI: 10.1080/19420862.2021.1919285
  Issue No: Vol. 13, No. 1 (2021)
The influence of antibody engineering on Fc conformation and Fc receptor
binding properties: Analysis of FcRn-binding engineered antibodies and an
Fc fusion protein
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  Authors: Takuo Suzuki, Noritaka Hashii, Minoru Tada, Akiko Ishii-Watabe
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-05-25T07:24:11Z
  DOI: 10.1080/19420862.2021.1923366
  Issue No: Vol. 13, No. 1 (2021)
Ensembles in solution as a new paradigm for antibody structure prediction
and design
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  Authors: Monica L. Fernández-Quintero, Guy Georges, Janos M. Varga, Klaus R. Liedl
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-05-25T07:18:07Z
  DOI: 10.1080/19420862.2021.1923122
  Issue No: Vol. 13, No. 1 (2021)
Potent SARS-CoV-2 binding and neutralization through maturation of iconic
SARS-CoV-1 antibodies
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  Authors: Romain Rouet, Ohan Mazigi, Gregory J. Walker, David B. Langley, Meghna Sobti, Peter Schofield, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Jake Y. Henry, Arunasingam Abayasingam, Deborah Burnett, Anthony Kelleher, Robert Brink, Rowena A. Bull, Stuart Turville, Alastair G. Stewart, Christopher C. Goodnow, William D. Rawlinson, Daniel Christ
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-05-24T08:10:22Z
  DOI: 10.1080/19420862.2021.1922134
  Issue No: Vol. 13, No. 1 (2021)
Collecting antibodies and large molecule biomarkers in mouse interstitial
brain fluid: a comparison of microdialysis and cerebral open flow
microperfusion
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  Authors: Florie Le Prieult, Erica Barini, Loic Laplanche, Kerstin Schlegel, Mario Mezler
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-05-16T11:40:54Z
  DOI: 10.1080/19420862.2021.1918819
  Issue No: Vol. 13, No. 1 (2021)
Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination
partner for cancer immunotherapy
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  Authors: Inja Waldhauer, Valeria Gonzalez-Nicolini, Anne Freimoser-Grundschober, Tapan K Nayak, Linda Fahrni, Ralf J. Hosse, Danny Gerrits, Edwin J. W. Geven, Johannes Sam, Sabine Lang, Esther Bommer, Virginie Steinhart, Elisabeth Husar, Sara Colombetti, Erwin Van Puijenbroek, Markus Neubauer, J. Mark Cline, Pradeep K. Garg, Gregory Dugan, Federica Cavallo, Gonzalo Acuna, Jehad Charo, Volker Teichgräber, Stefan Evers, Otto C. Boerman, Marina Bacac, Ekkehard Moessner, Pablo Umaña, Christian Klein
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-05-11T06:19:48Z
  DOI: 10.1080/19420862.2021.1913791
  Issue No: Vol. 13, No. 1 (2021)
Animal immunization merges with innovative technologies: A new paradigm
shift in antibody discovery
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  Authors: Ponraj Prabakaran, Sambasiva P Rao, Maria Wendt
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-05-05T08:36:47Z
  DOI: 10.1080/19420862.2021.1924347
  Issue No: Vol. 13, No. 1 (2021)
Targeting cancer homing into the lymph node with a novel anti-CCR7
therapeutic antibody: the paradigm of CLL
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  Authors: Carlos Cuesta-Mateos, Raquel Juárez-Sánchez, Tamara Mateu-Albero, Javier Loscertales, Wim Mol, Fernando Terrón, Cecilia Muñoz-Calleja
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-05-04T01:38:45Z
  DOI: 10.1080/19420862.2021.1917484
  Issue No: Vol. 13, No. 1 (2021)
N-terminal selective conjugation method widens the therapeutic window of
antibody–drug conjugates by improving tolerability and stability
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  Authors: Min Ji Ko, Daehae Song, Juhee Kim, Jae Yong Kim, Jaehyun Eom, Byungje Sung, Yong-Gyu Son, Young Min Kim, Sang Hoon Lee, Weon-Kyoo You, Jinwon Jung
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-04-27T09:59:56Z
  DOI: 10.1080/19420862.2021.1914885
  Issue No: Vol. 13, No. 1 (2021)
A platform-agnostic, function first-based antibody discovery strategy
using plasmid-free mammalian expression of antibodies
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  Authors: Ruijun Zhang, Ponraj Prabakaran, Xiaocong Yu, Brian C. Mackness, Ekaterina Boudanova, Joern Hopke, Jose Sancho, Jacqueline Saleh, HyunSuk Cho, Ningning Zhang, Helene Simonds-Mannes, Samuel D. Stimple, Dietmar Hoffmann, Anna Park, Partha S. Chowdhury, Sambasiva P. Rao
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-04-26T06:27:17Z
  DOI: 10.1080/19420862.2021.1904546
  Issue No: Vol. 13, No. 1 (2021)
Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in
gemcitabine-resistant pancreatic cancer models
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  Authors: Emilia Rabia, Véronique Garambois, Julie Hubert, Marine Bruciamacchie, Nelly Pirot, Hélène Delpech, Morgane Broyon, Charles Theillet, Pierre-Emmanuel Colombo, Nadia Vie, Diego Tosi, Celine Gongora, Lakhdar Khellaf, Marta Jarlier, Nina Radosevic-Robin, Thierry Chardès, André Pèlegrin, Christel Larbouret
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-04-20T09:33:09Z
  DOI: 10.1080/19420862.2021.1914883
  Issue No: Vol. 13, No. 1 (2021)
Protective antibodies against human parainfluenza virus type 3 infection
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  Authors: Jim Boonyaratanakornkit, Suruchi Singh, Connor Weidle, Justas Rodarte, Ramasamy Bakthavatsalam, Jonathan Perkins, Guillaume B.E. Stewart-Jones, Peter D. Kwong, Andrew T. McGuire, Marie Pancera, Justin J. Taylor
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-04-20T09:24:59Z
  DOI: 10.1080/19420862.2021.1912884
  Issue No: Vol. 13, No. 1 (2021)
Development of a mechanism of action-reflective, dual target cell-based
reporter bioassay for a bispecific monoclonal antibody targeting human
CTLA-4 and PD-1
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  Authors: Weimin Chen, Madhu Pandey, Hong Sun, Andrea Rolong, Mingyan Cao, Dengfeng Liu, Jihong Wang, Lingmin Zeng, Alan Hunter, Shihua Lin
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-04-19T06:20:43Z
  DOI: 10.1080/19420862.2021.1914359
  Issue No: Vol. 13, No. 1 (2021)
Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid
protein
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  Authors: Curtis D. Hodge, Daniel. J. Rosenberg, Patricia Grob, Mateusz Wilamowski, Andrzej Joachimiak, Greg L. Hura, Michal Hammel
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-04-12T09:56:13Z
  DOI: 10.1080/19420862.2021.1905978
  Issue No: Vol. 13, No. 1 (2021)
Developments and opportunities in continuous biopharmaceutical
manufacturing
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  Authors: Ohnmar Khanal, Abraham M. Lenhoff
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-04-11T05:56:12Z
  DOI: 10.1080/19420862.2021.1903664
  Issue No: Vol. 13, No. 1 (2021)
Calculation of therapeutic antibody viscosity with coarse-grained models,
hydrodynamic calculations and machine learning-based parameters
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  Authors: Pin-Kuang Lai, James W. Swan, Bernhardt L. Trout
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-04-09T09:47:34Z
  DOI: 10.1080/19420862.2021.1907882
  Issue No: Vol. 13, No. 1 (2021)
TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine
release in preclinical models of B-NHL
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  Authors: Harbani K. Malik-Chaudhry, Kirthana Prabhakar, Harshad S. Ugamraj, Andrew A. Boudreau, Benjamin Buelow, Kevin Dang, Laura M. Davison, Katherine E. Harris, Brett Jorgensen, Heather Ogana, Duy Pham, Ute Schellenberger, Wim Van Schooten, Roland Buelow, Suhasini Iyer, Nathan D. Trinklein, Udaya S. Rangaswamy
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-04-05T05:46:12Z
  DOI: 10.1080/19420862.2021.1890411
  Issue No: Vol. 13, No. 1 (2021)
A bivalent, bispecific Dab-Fc antibody molecule for dual targeting of HER2
and HER3
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  Authors: Alexander Rau, Katharina Kocher, Mirjam Rommel, Lennart Kühl, Maximilian Albrecht, Hannes Gotthard, Nadine Aschmoneit, Bettina Noll, Monilola A. Olayioye, Roland E. Kontermann, Oliver Seifert
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-03-23T04:57:43Z
  DOI: 10.1080/19420862.2021.1902034
  Issue No: Vol. 13, No. 1 (2021)
Immunogenicity risk assessment for biotherapeutics through in vitro
detection of CD134 and CD137 on T helper cells
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  Authors: Sivan Cohen, Srividya Myneni, Anna Batt, Joyce Guerrero, Jochen Brumm, Shan Chung
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-03-17T09:04:10Z
  DOI: 10.1080/19420862.2021.1898831
  Issue No: Vol. 13, No. 1 (2021)
Data mining patented antibody sequences
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  Authors: Konrad Krawczyk, Andrew Buchanan, Paolo Marcatili
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-03-16T06:30:00Z
  DOI: 10.1080/19420862.2021.1892366
  Issue No: Vol. 13, No. 1 (2021)
Functional GLP-1R antibodies identified from a synthetic GPCR-focused
library demonstrate potent blood glucose control
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  Authors: Qiang Liu, Pankaj Garg, Burcu Hasdemir, Linya Wang, Emily Tuscano, Emily Sever, Erica Keane, Ana G Lujan Hernandez, Tom Z. Yuan, Eric Kwan, Joyce Lai, Greg Szot, Sreenivasan Paruthiyil, Fumiko Axelrod, Aaron K. Sato
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-03-12T09:01:22Z
  DOI: 10.1080/19420862.2021.1893425
  Issue No: Vol. 13, No. 1 (2021)
Extended plasma half-life of albumin-binding domain fused human IgA upon
pH-dependent albumin engagement of human FcRn in vitro and in vivo
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  Authors: Simone Mester, Mitchell Evers, Saskia Meyer, Jeannette Nilsen, Victor Greiff, Inger Sandlie, Jeanette Leusen, Jan Terje Andersen
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-03-11T06:02:25Z
  DOI: 10.1080/19420862.2021.1893888
  Issue No: Vol. 13, No. 1 (2021)
Fc galactosylation follows consecutive reaction kinetics and enhances
immunoglobulin G hexamerization for complement activation
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  Authors: Bingchuan Wei, Xuan Gao, Lance Cadang, Saeed Izadi, Peilu Liu, Hui-Min Zhang, Elizabeth Hecht, Jeongsup Shim, Gordon Magill, Juan Rincon Pabon, Lu Dai, Wilson Phung, Elaine Lin, Christopher Wang, Kevin Whang, Sean Sanchez, Jose Oropeza Jr, Julien Camperi, Jennifer Zhang, Wendy Sandoval, Yonghua Taylor Zhang, Guoying Jiang
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-03-08T01:20:55Z
  DOI: 10.1080/19420862.2021.1893427
  Issue No: Vol. 13, No. 1 (2021)
Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing
Spike epitopes demonstrate enhanced potency against SARS-CoV-2
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  Authors: Shion A. Lim, Josef A. Gramespacher, Katarina Pance, Nicholas J. Rettko, Paige Solomon, Jing Jin, Irene Lui, Susanna K. Elledge, Jia Liu, Colton J. Bracken, Graham Simmons, Xin X. Zhou, Kevin K. Leung, James A. Wells
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-03-05T11:45:27Z
  DOI: 10.1080/19420862.2021.1893426
  Issue No: Vol. 13, No. 1 (2021)
Identification of critical chemical modifications and paratope mapping by
size exclusion chromatography of stressed antibody-target complexes
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  Authors: Pavel V. Bondarenko, Andrew C. Nichols, Gang Xiao, Rachel Liuqing Shi, Pik Kay Chan, Thomas M Dillon, Fernando Garces, David J. Semin, Margaret S. Ricci
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-02-21T03:08:48Z
  DOI: 10.1080/19420862.2021.1887629
  Issue No: Vol. 13, No. 1 (2021)
Identification of critical chemical modifications by size exclusion
chromatography of stressed antibody-target complexes with competitive
binding
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  Authors: Rachel Liuqing Shi, Gang Xiao, Thomas M. Dillon, Arnold McAuley, Margaret S. Ricci, Pavel V. Bondarenko
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-02-21T02:58:09Z
  DOI: 10.1080/19420862.2021.1887612
  Issue No: Vol. 13, No. 1 (2021)
Coming together at the hinges: Therapeutic prospects of IgG3
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  Authors: Thach H. Chu, Edward F. Patz, Margaret E. Ackerman
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-02-19T08:44:23Z
  DOI: 10.1080/19420862.2021.1882028
  Issue No: Vol. 13, No. 1 (2021)
Off-target binding of an anti-amyloid beta monoclonal antibody to platelet
factor 4 causes acute and chronic toxicity in cynomolgus monkeys
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  Authors: Lise I. Loberg, Meha Chhaya, Alexander Ibraghimov, Edit Tarcsa, Andreas Striebinger, Andreas Popp, Lili Huang, Frank Oellien, Stefan Barghorn
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-02-18T07:20:38Z
  DOI: 10.1080/19420862.2021.1887628
  Issue No: Vol. 13, No. 1 (2021)
Combining random mutagenesis, structure-guided design and next-generation
sequencing to mitigate polyreactivity of an anti-IL-21R antibody
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  Authors: Sharon M. Campbell, Joseph DeBartolo, James R. Apgar, Lydia Mosyak, Virginie McManus, Sonia Beyer, Eric M. Bennett, Matthew Lambert, Orla Cunningham
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-02-09T08:56:43Z
  DOI: 10.1080/19420862.2021.1883239
  Issue No: Vol. 13, No. 1 (2021)
One size does not fit all: navigating the multi-dimensional space to
optimize T-cell engaging protein therapeutics
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  Authors: Wei Chen, Fan Yang, Carole Wang, Jatin Narula, Edward Pascua, Irene Ni, Sheng Ding, Xiaodi Deng, Matthew Ling-Hon Chu, Amber Pham, Xiaoyue Jiang, Kevin C. Lindquist, Patrick J. Doonan, Tom Van Blarcom, Yik Andy Yeung, Javier Chaparro-Riggers
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-02-09T08:44:22Z
  DOI: 10.1080/19420862.2020.1871171
  Issue No: Vol. 13, No. 1 (2021)
Innovative approaches to biologic development on the trail of CT-P13:
biosimilars, value-added medicines, and biobetters
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  Authors: HoUng Kim, Rieke Alten, Fraser Cummings, Silvio Danese, Geert D’Haens, Paul Emery, Subrata Ghosh, Cyrielle Gilletta de Saint Joseph, JongHyuk Lee, James O. Lindsay, Elena Nikiphorou, Ben Parker, Stefan Schreiber, Steven Simoens, Rene Westhovens, Ji Hoon Jeong, Laurent Peyrin-Biroulet
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-02-09T06:20:46Z
  DOI: 10.1080/19420862.2020.1868078
  Issue No: Vol. 13, No. 1 (2021)
Brain pharmacokinetics of anti-transferrin receptor antibody affinity
variants in rats determined using microdialysis
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  Authors: Hsueh-Yuan Chang, Shengjia Wu, Yingyi Li, Wanying Zhang, Matthew Burrell, Carl I. Webster, Dhaval K. Shah
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-01-27T07:32:35Z
  DOI: 10.1080/19420862.2021.1874121
  Issue No: Vol. 13, No. 1 (2021)
Common light chain chickens produce human antibodies of high affinity and
broad epitope coverage for the engineering of bispecifics
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  Authors: Kathryn H. Ching, Kimberley Berg, Kevin Reynolds, Darlene Pedersen, Alba Macias, Yasmina N. Abdiche, William D. Harriman, Philip A. Leighton
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-01-25T12:51:22Z
  DOI: 10.1080/19420862.2020.1862451
  Issue No: Vol. 13, No. 1 (2021)
Bispecific antibody target pair discovery by high-throughput phenotypic
screening using in vitro combinatorial Fab libraries
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  Authors: Pallavi Bhatta, Kevin D. Whale, Amy K. Sawtell, Clare L. Thompson, Stephen E. Rapecki, David A. Cook, Breda M. Twomey, Milena Mennecozzi, Laura E. Starkie, Emily M. C. Barry, Shirley J. Peters, Ahmad M. Kamal, Helene M. Finney
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-01-25T09:37:22Z
  DOI: 10.1080/19420862.2020.1859049
  Issue No: Vol. 13, No. 1 (2021)
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific
antibody for the treatment of solid tumors
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  Authors: Adam R. Root, Gurkan Guntas, Madan Katragadda, James R. Apgar, Jatin Narula, Chew Shun Chang, Sara Hanscom, Matthew McKenna, Jason Wade, Caryl Meade, Weijun Ma, Yongjing Guo, Yan Liu, Weili Duan, Claire Hendershot, Amy C. King, Yan Zhang, Eric Sousa, Amy Tam, Susan Benard, Han Yang, Kerry Kelleher, Fang Jin, Nicole Piche-Nicholas, Sinead E. Keating, Fernando Narciandi, Rosemary Lawrence-Henderson, Maya Arai, Wayne R. Stochaj, Kristine Svenson, Lidia Mosyak, Khetemcnee Lam, Christopher Francis, Kimberly Marquette, Liliana Wroblewska, H. Lily Zhu, Alfredo Darmanin Sheehan, Edward R. LaVallie, Aaron M. D’Antona, Alison Betts, Lindsay King, Edward Rosfjord, Orla Cunningham, Laura Lin, Puja Sapra, Lioudmila Tchistiakova, Divya Mathur, Laird Bloom
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-01-18T10:33:21Z
  DOI: 10.1080/19420862.2020.1850395
  Issue No: Vol. 13, No. 1 (2021)
Antibodies to watch in 2021
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  Authors: Hélène Kaplon, Janice M. Reichert
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-01-18T06:54:28Z
  DOI: 10.1080/19420862.2020.1860476
  Issue No: Vol. 13, No. 1 (2021)
Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the
same epitope
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  Authors: Wing Ki Wong, Sarah A. Robinson, Alexander Bujotzek, Guy Georges, Alan P. Lewis, Jiye Shi, James Snowden, Bruck Taddese, Charlotte M. Deane
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-01-15T10:03:52Z
  DOI: 10.1080/19420862.2021.1873478
  Issue No: Vol. 13, No. 1 (2021)
In memoriam: Jefferson Foote
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  Authors: E. Sally Ward, Peter Jones, Tim Buss, Cristina Rada, Gregory Winter, Richard Willson
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-01-13T06:15:48Z
  DOI: 10.1080/19420862.2020.1870059
  Issue No: Vol. 13, No. 1 (2021)
A computational method for immune repertoire mining that identifies novel
binders from different clonotypes, demonstrated by identifying
anti-pertussis toxoid antibodies
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  Authors: Eve Richardson, Jacob D. Galson, Paul Kellam, Dominic F. Kelly, Sarah E. Smith, Anne Palser, Simon Watson, Charlotte M. Deane
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-01-11T02:33:14Z
  DOI: 10.1080/19420862.2020.1869406
  Issue No: Vol. 13, No. 1 (2021)
Antibody-mediated delivery of LIGHT to the tumor boosts natural killer
cells and delays tumor progression
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  Authors: Marco Stringhini, Jacqueline Mock, Vanessa Fontana, Patrizia Murer, Dario Neri
  Abstract: Volume 13, Issue 1, January-December 2021
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  Citation: mAbs
  PubDate: 2021-01-06T02:02:23Z
  DOI: 10.1080/19420862.2020.1868066
  Issue No: Vol. 13, No. 1 (2021)
Rational selection of building blocks for the assembly of bispecific
antibodies
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  Authors: Danyang Gong, Timothy P. Riley, Krzysztof P. Bzymek, Ana R. Correia, Danqing Li, Christopher Spahr, John H. Robinson, Ryan B. Case, Zhulun Wang, Fernando Garces
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-01-05T08:01:15Z
  DOI: 10.1080/19420862.2020.1870058
  Issue No: Vol. 13, No. 1 (2021)
Activity of murine surrogate antibodies for durvalumab and tremelimumab
lacking effector function and the ability to deplete regulatory T cells in
mouse models of cancer
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  Authors: Darren J. Schofield, Jennifer Percival-Alwyn, Mateusz Rytelewski, John Hood, Raymond Rothstein, Leslie Wetzel, Kelly McGlinchey, Grace Adjei, Amanda Watkins, LeeAnn Machiesky, Weimin Chen, John Andrews, Maria Groves, Michelle Morrow, Ross A. Stewart, Andrew Leinster, Robert W. Wilkinson, Scott A. Hammond, Nadia Luheshi, Claire Dobson, Michael Oberst
  Abstract: Volume 13, Issue 1, January-December 2021
  .
  
  Citation: mAbs
  PubDate: 2021-01-05T07:59:05Z
  DOI: 10.1080/19420862.2020.1857100
  Issue No: Vol. 13, No. 1 (2021)