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Diabetes Management
Number of Followers: 15 ![]() ISSN (Print) 1758-1907 Published by Future Medicine ![]() |
- Development of a fully canine anti-canine CTLA4 monoclonal antibody for
comparative translational research in dogs with spontaneous tumors
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Authors: Nicola J. Mason, Nicholas Chester, Ailian Xiong, Antonia Rotolo, Ying Wu, Sho Yoshimoto, Patrick Glassman, Gayathri Gulendran, Don L. Siegel
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-12-03T03:58:05Z
DOI: 10.1080/19420862.2021.2004638
Issue No: Vol. 13, No. 1 (2021)
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- Drug-like antibodies with high affinity, diversity and developability
directly from next-generation antibody libraries
Open Access Article
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Authors: Andre Azevedo Reis Teixeira, Michael Frank Erasmus, Sara D’Angelo, Leslie Naranjo, Fortunato Ferrara, Camila Leal-Lopes, Oliver Durrant, Cecile Galmiche, Aleardo Morelli, Anthony Scott-Tucker, Andrew Raymon Morton Bradbury
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-12-01T11:44:27Z
DOI: 10.1080/19420862.2021.1980942
Issue No: Vol. 13, No. 1 (2021)
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- Agonistic nanobodies and antibodies to human VISTA
Open Access Article
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Authors: Yu-Heng Vivian Ma, Amanda Sparkes, Ema Romão, Shrayasee Saha, Jean Gariépy
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-11-24T07:39:48Z
DOI: 10.1080/19420862.2021.2003281
Issue No: Vol. 13, No. 1 (2021)
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- Hydrogen-deuterium exchange mass spectrometry reveals three unique binding
responses of mAbs directed to the catalytic domain of hCAIX
Open Access Article
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Authors: Joey G. Sheff, John F. Kelly, Anna Robotham, Traian Sulea, Félix Malenfant, Denis L’Abbé, Mélanie Duchesne, Alex Pelletier, Jean Lefebvre, Andrea Acel, Marie Parat, Mylene Gosselin, Cunle Wu, Yves Fortin, Jason Baardsnes, Henk Van Faassen, Shannon Awrey, Shawn C. Chafe, Paul C. McDonald, Shoukat Dedhar, Anne E.G. Lenferink
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-11-23T10:34:08Z
DOI: 10.1080/19420862.2021.1997072
Issue No: Vol. 13, No. 1 (2021)
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- Isolation and characterization of monoclonal antibodies against human
carbonic anhydrase-IX
Open Access Article
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Authors: Anne E.G. Lenferink, Paul C. McDonald, Christiane Cantin, Suzanne Grothé, Mylene Gosselin, Jason Baardsnes, Myriam Banville, Paul Lachance, Alma Robert, Yuneivy Cepero-Donates, Stevo Radinovic, Patrick Salois, Marie Parat, Hafida Oamari, Annie Dulude, Mehul Patel, Martin Lafrance, Andrea Acel, Nathalie Bousquet-Gagnon, Denis L’Abbé, Alex Pelletier, Félix Malenfant, Maria Jaramillo, Maureen O’Connor-Mccourt, Cunle Wu, Yves Durocher, Mélanie Duchesne, Christine Gadoury, Anne Marcil, Yves Fortin, Beatrice Paul-Roc, Maurizio Acchione, Shawn C. Chafe, Oksana Nemirovsky, Joseph Lau, Francois Bénard, Shoukat Dedhar
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-11-22T07:21:50Z
DOI: 10.1080/19420862.2021.1999194
Issue No: Vol. 13, No. 1 (2021)
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- An efficient system for bioconjugation based on a widely applicable
engineered O-glycosylation tag
Open Access Article
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Authors: Thomas V. Murray, Kasia Kozakowska-McDonnell, Adam Tibbles, Annabel Taylor, Daniel Higazi, Emmanuel Rossy, Alessandra Rossi, Sivaneswary Genapathy, Giulia Tamburrino, Nicola Rath, Natalie Tigue, Vivian Lindo, Tristan Vaughan, Monika A. Papworth
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-11-16T09:33:11Z
DOI: 10.1080/19420862.2021.1992068
Issue No: Vol. 13, No. 1 (2021)
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- Current strategies for detecting functional convergence across B-cell
receptor repertoires
Open Access Article
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Authors: Matthew I. J. Raybould, Anthony R. Rees, Charlotte M. Deane
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-11-16T09:23:38Z
DOI: 10.1080/19420862.2021.1996732
Issue No: Vol. 13, No. 1 (2021)
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- Development of a robust and semi-automated two-step antibody purification
process
Open Access Article
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Authors: Xiaomin Yang, Richard Yuan, Christopher Garcia, Jessica Berry, Denisa Foster, Dongmei He, Gui-Feng Zhang, Bryan E. Jones
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-11-16T05:35:37Z
DOI: 10.1080/19420862.2021.2000348
Issue No: Vol. 13, No. 1 (2021)
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- Polyreactivity and polyspecificity in therapeutic antibody development:
risk factors for failure in preclinical and clinical development campaigns
Open Access Article
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Authors: Orla Cunningham, Martin Scott, Zhaohui Sunny Zhou, William J.J. Finlay
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-11-15T05:05:35Z
DOI: 10.1080/19420862.2021.1999195
Issue No: Vol. 13, No. 1 (2021)
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- The impact of immunogenicity on therapeutic antibody pharmacokinetics: A
preclinical evaluation of the effect of immune complex formation and
antibody effector function on clearance
Open Access Article
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Authors: Eugenia Opolka-Hoffmann, Gregor Jordan, Michael Otteneder, Robin Kieferle, Martin Lechmann, Gerhard Winter, Roland F. Staack
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-11-12T07:59:52Z
DOI: 10.1080/19420862.2021.1995929
Issue No: Vol. 13, No. 1 (2021)
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- Impact of IgG subclass on molecular properties of monoclonal antibodies
Open Access Article
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Authors: Yu Tang, Paul Cain, Victor Anguiano, James J. Shih, Qing Chai, Yiqing Feng
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-11-12T07:55:53Z
DOI: 10.1080/19420862.2021.1993768
Issue No: Vol. 13, No. 1 (2021)
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- Differences in human IgG1 and IgG4 S228P monoclonal antibodies viscosity
and self-interactions: Experimental assessment and computational
predictions of domain interactions
Open Access Article
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Authors: Pin-Kuang Lai, Gaurav Ghag, Yao Yu, Veronica Juan, Laurence Fayadat-Dilman, Bernhardt L. Trout
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-11-08T11:10:54Z
DOI: 10.1080/19420862.2021.1991256
Issue No: Vol. 13, No. 1 (2021)
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- Viro-antibody therapy: engineering oncolytic viruses for genetic delivery
of diverse antibody-based biotherapeutics
Open Access Article
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Authors: Roland E. Kontermann, Guy Ungerechts, Dirk M. Nettelbeck
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-11-08T10:24:15Z
DOI: 10.1080/19420862.2021.1982447
Issue No: Vol. 13, No. 1 (2021)
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- Identification of a CE-SDS shoulder peak as disulfide-linked fragments
from common CH2 cleavages in IgGs and IgG-like bispecific antibodies
Open Access Article
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Authors: Mingyan Cao, Yang Jiao, Conner Parthemore, Samuel Korman, Jiao Ma, Alan Hunter, Greg Kilby, Xiaoyu Chen
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-11-01T07:27:15Z
DOI: 10.1080/19420862.2021.1981806
Issue No: Vol. 13, No. 1 (2021)
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- Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for
the treatment of cancer
Open Access Article
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Authors: Hong Xiang, Abigael G. Chan, Ago Ahene, David I. Bellovin, Rong Deng, Amy W. Hsu, Ursula Jeffry, Servando Palencia, Janine Powers, James Zanghi, Helen Collins
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-11-01T07:20:28Z
DOI: 10.1080/19420862.2021.1981202
Issue No: Vol. 13, No. 1 (2021)
-
- Effect of variable domain charge on in vitro and in vivo disposition of
monoclonal antibodies
Open Access Article
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Authors: Shufang Liu, Ashwni Verma, Hubert Kettenberger, Wolfgang F. Richter, Dhaval K. Shah
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-29T06:48:10Z
DOI: 10.1080/19420862.2021.1993769
Issue No: Vol. 13, No. 1 (2021)
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- Nonclinical safety evaluation, pharmacokinetics, and target engagement of
Lu AF82422, a monoclonal IgG1 antibody against alpha-synuclein in
development for treatment of synucleinopathies
Open Access Article
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Authors: Lone Fjord-Larsen, Annemette Thougaard, Karen Malene Wegener, Joan Christiansen, Frank Larsen, Lise Maj Schrøder-Hansen, Marianne Kaarde, Dorte Kornerup Ditlevsen
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-28T08:32:14Z
DOI: 10.1080/19420862.2021.1994690
Issue No: Vol. 13, No. 1 (2021)
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- Novel chimeric monoclonal antibodies that block fentanyl effects and alter
fentanyl biodistribution in mice
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Authors: Bhupal Ban, Rodell C. Barrientos, Therese Oertel, Essie Komla, Connor Whalen, Megan Sopko, Yingjian You, Partha Banerjee, Agnieszka Sulima, Arthur E. Jacobson, Kenner C. Rice, Gary R. Matyas, Vidadi Yusibov
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-25T10:20:15Z
DOI: 10.1080/19420862.2021.1991552
Issue No: Vol. 13, No. 1 (2021)
-
- Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig
receptor display neutralization activity and mucosal enrichment
Open Access Article
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Authors: Ian White, Ninkka Tamot, Rajitha Doddareddy, Jason Ho, Qun Jiao, Paul B. Harvilla, Tong-Yuan Yang, Brian Geist, M. Jack Borrok, Matthew D. Truppo, Rajkumar Ganesan, Partha Chowdhury, Adam Zwolak
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-25T10:15:54Z
DOI: 10.1080/19420862.2021.1987180
Issue No: Vol. 13, No. 1 (2021)
-
- Fc gamma receptor IIIb binding of individual antibody proteoforms resolved
by affinity chromatography–mass spectrometry
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Authors: Steffen Lippold, Alexander Knaupp, Arnoud H. de Ru, Rayman T. N. Tjokrodirijo, Peter A. van Veelen, Erwin van Puijenbroek, Steven W. de Taeye, Dietmar Reusch, Gestur Vidarsson, Manfred Wuhrer, Tilman Schlothauer, David Falck
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-22T03:41:00Z
DOI: 10.1080/19420862.2021.1982847
Issue No: Vol. 13, No. 1 (2021)
-
- Antibody mix-and-read assays based on fluorescence intensity probes
Open Access Article
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Authors: Ujwal Patil, Atul Goyal, Binh Vu, Yanyun Liu, Vijay Maranholkar, Katerina Kourentzi, James M. Briggs, Richard C. Willson
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-18T09:35:24Z
DOI: 10.1080/19420862.2021.1980178
Issue No: Vol. 13, No. 1 (2021)
-
- Structure-based charge calculations for predicting isoelectric point,
viscosity, clearance, and profiling antibody therapeutics
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Authors: Nels Thorsteinson, John R. Gunn, Kenneth Kelly, Will Long, Paul Labute
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-10T05:49:45Z
DOI: 10.1080/19420862.2021.1981805
Issue No: Vol. 13, No. 1 (2021)
-
- Quantification of natural abundance NMR data differentiates the solution
behavior of monoclonal antibodies and their fragments
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Authors: David Ban, Cory T. Rice, Mark A. McCoy
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-06T03:43:48Z
DOI: 10.1080/19420862.2021.1978132
Issue No: Vol. 13, No. 1 (2021)
-
- Antibody blockade of CD96 by distinct molecular mechanisms
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Authors: Peter S. Lee, Bryant Chau, Ishita Barman, Christine Bee, Aarti Jashnani, Jason M. Hogan, Barbara Aguilar, Gavin Dollinger, Arvind Rajpal, Pavel Strop
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-01T11:45:50Z
DOI: 10.1080/19420862.2021.1979800
Issue No: Vol. 13, No. 1 (2021)
-
- Selective depletion of radiolabeled HER2-specific antibody for contrast
improvement during PET
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Authors: Priyanka Khare, Wei Sun, Sreevidhya Ramakrishnan, Guiyang Hao, Su-Tang Lo, Kien Nham, Xiankai Sun, Raimund J. Ober, E. Sally Ward, Rafal Swiercz
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-10-01T03:55:36Z
DOI: 10.1080/19420862.2021.1976705
Issue No: Vol. 13, No. 1 (2021)
-
- Enhancing the multi-attribute method through an automated and
high-throughput sample preparation
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Authors: Pongkwan Sitasuwan, Thomas W. Powers, Tiffany Medwid, Yuting Huang, Bradley Bare, L. Andrew Lee
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-09-29T05:20:31Z
DOI: 10.1080/19420862.2021.1978131
Issue No: Vol. 13, No. 1 (2021)
-
- Versatile and rapid microfluidics-assisted antibody discovery
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Authors: Ramona Gaa, Emmanuel Menang-Ndi, Shruti Pratapa, Christine Nguyen, Satyendra Kumar, Achim Doerner
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-09-29T02:12:13Z
DOI: 10.1080/19420862.2021.1978130
Issue No: Vol. 13, No. 1 (2021)
-
- Allometric scaling of therapeutic monoclonal antibodies in preclinical and
clinical settings
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Authors: Eva Germovsek, Ming Cheng, Craig Giragossian
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-09-17T06:48:08Z
DOI: 10.1080/19420862.2021.1964935
Issue No: Vol. 13, No. 1 (2021)
-
- Ten years in the making: application of CrossMab technology for the
development of therapeutic bispecific antibodies and antibody fusion
proteins
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Authors: Marlena Surowka, Wolfgang Schaefer, Christian Klein
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-09-07T06:36:32Z
DOI: 10.1080/19420862.2021.1967714
Issue No: Vol. 13, No. 1 (2021)
-
- Characterizing and understanding the formation of cysteine conjugates and
other by-products in a random, lysine-linked antibody drug conjugate
Open Access Article
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Authors: Difei Qiu, Yande Huang, Naresh Chennamsetty, Scott A. Miller, Michael Hay
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-09-05T01:22:22Z
DOI: 10.1080/19420862.2021.1974150
Issue No: Vol. 13, No. 1 (2021)
-
- Sensitive, homogeneous, and label-free protein-probe assay for antibody
aggregation and thermal stability studies
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Authors: Salla Valtonen, Emmiliisa Vuorinen, Ville Eskonen, Morteza Malakoutikhah, Kari Kopra, Harri Härmä
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-30T08:00:27Z
DOI: 10.1080/19420862.2021.1955810
Issue No: Vol. 13, No. 1 (2021)
-
- A non-clinical comparative study of IL-23 antibodies in psoriasis
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Authors: Li Zhou, Yibing Wang, Qi Wan, Fei Wu, Jeffrey Barbon, Robert Dunstan, Stephen Gauld, Mark Konrad, Laura Leys, Richard McCarthy, Marian Namovic, Christine Nelson, Gary Overmeyer, Denise Perron, Zhi Su, Leyu Wang, Susan Westmoreland, Jun Zhang, Rui Zhu, Geertruida Veldman
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-30T04:33:43Z
DOI: 10.1080/19420862.2021.1964420
Issue No: Vol. 13, No. 1 (2021)
-
- Correction
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Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-25T06:59:10Z
DOI: 10.1080/19420862.2021.1966993
Issue No: Vol. 13, No. 1 (2021)
-
- Accurate determination of epitope for antibodies with unknown 3D
structures
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Authors: Shifa Tahir, Thomas Bourquard, Astrid Musnier, Yann Jullian, Yannick Corde, Zakaria Omahdi, Laetitia Mathias, Eric Reiter, Pascale Crépieux, Gilles Bruneau, Anne Poupon
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-25T06:57:15Z
DOI: 10.1080/19420862.2021.1961349
Issue No: Vol. 13, No. 1 (2021)
-
- Improved epitope resolution of the prefusion trimer-specific antibody AM14
bound to the RSV F glycoprotein
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Authors: Wayne Harshbarger, Priyanka D. Abeyrathne, Sai Tian, Ying Huang, Sumana Chandramouli, Matthew James Bottomley, Enrico Malito
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-23T07:35:13Z
DOI: 10.1080/19420862.2021.1955812
Issue No: Vol. 13, No. 1 (2021)
-
- Untargeted proteomics reveals upregulation of stress response pathways
during CHO-based monoclonal antibody manufacturing process leading to
disulfide bond reduction
Open Access Article
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Authors: Seo-Young Park, Susan Egan, Anthony J. Cura, Kathryn L. Aron, Xuankuo Xu, Mengyuan Zheng, Michael Borys, Sanchayita Ghose, Zhengjian Li, Kyongbum Lee
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-23T06:21:58Z
DOI: 10.1080/19420862.2021.1963094
Issue No: Vol. 13, No. 1 (2021)
-
- An end-to-end automated platform process for high-throughput engineering
of next-generation multi-specific antibody therapeutics
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Authors: Norbert Furtmann, Marion Schneider, Nadja Spindler, Bjoern Steinmann, Ziyu Li, Ingo Focken, Joachim Meyer, Dilyana Dimova, Katja Kroll, Wulf Dirk Leuschner, Audrey Debeaumont, Magali Mathieu, Christian Lange, Werner Dittrich, Jochen Kruip, Thorsten Schmidt, Joerg Birkenfeld
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-08-12T02:53:58Z
DOI: 10.1080/19420862.2021.1955433
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- Host cell protein profiling of commercial therapeutic protein drugs as a
benchmark for monoclonal antibody-based therapeutic protein development
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Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-07T07:04:44Z
DOI: 10.1080/19420862.2021.1955811
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- Development of potent and effective synthetic SARS-CoV-2 neutralizing
nanobodies
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Authors: Maxwell A. Stefan, Yooli K. Light, Jennifer L. Schwedler, Peter R. McIlroy, Colleen M. Courtney, Edwin A. Saada, Christine E. Thatcher, Ashlee M. Phillips, Feliza A. Bourguet, Catherine M. Mageeney, Summer A. McCloy, Nicole M. Collette, Oscar A. Negrete, Joseph S. Schoeniger, Dina R. Weilhammer, Brooke Harmon
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-04T11:50:56Z
DOI: 10.1080/19420862.2021.1958663
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- Targeting and pharmacology of an anti-IL13Rα2 antibody and antibody-drug
conjugate in a melanoma xenograft model
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Authors: Parul Gupta, Ziyue Karen Jiang, Bing Yang, Lisa Manzuk, Edward Rosfjord, Johnny Yao, Luanna Lemon, Kavon Noorbehesht, John David, Sujiet Puthenveetil, Jeffrey M. Casavant, Elwira Muszynska, Fengping Li, Mauricio Leal, Puja Sapra, Anand Giddabasappa
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-04T06:44:38Z
DOI: 10.1080/19420862.2021.1958662
Issue No: Vol. 13, No. 1 (2021)
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- Host cell protein detection gap risk mitigation: quantitative IAC-MS for
ELISA antibody reagent coverage determination
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Authors: Daniel M. Waldera-Lupa, Yvonne Jasper, Pia Köhne, Ronja Schwichtenhövel, Heiner Falkenberg, Thomas Flad, Peter Happersberger, Bernd Reisinger, Alireza Dehghani, Roland Moussa, Thomas Waerner
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-08-04T06:41:11Z
DOI: 10.1080/19420862.2021.1955432
Issue No: Vol. 13, No. 1 (2021)
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- A matrix of structure-based designs yields improved VRC01-class antibodies
for HIV-1 therapy and prevention
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Authors: Young D. Kwon, Mangaiarkarasi Asokan, Jason Gorman, Baoshan Zhang, Qingbo Liu, Mark K. Louder, Bob C. Lin, Krisha McKee, Amarendra Pegu, Raffaello Verardi, Eun Sung Yang, VRC Production Program, Kevin Carlton, Nicole A. Doria-Rose, Paolo Lusso, John R. Mascola, Peter D. Kwong
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-30T10:22:15Z
DOI: 10.1080/19420862.2021.1946918
Issue No: Vol. 13, No. 1 (2021)
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- Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell
engager targeting EGFR-positive tumors
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Authors: Susanne Wingert, Uwe Reusch, Stefan Knackmuss, Michael Kluge, Michael Damrat, Jens Pahl, Ute Schniegler-Mattox, Thomas Mueller, Ivica Fucek, Kristina Ellwanger, Michael Tesar, Torsten Haneke, Joachim Koch, Martin Treder, Wolfgang Fischer, Erich Rajkovic
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-30T08:10:51Z
DOI: 10.1080/19420862.2021.1950264
Issue No: Vol. 13, No. 1 (2021)
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- Preclinical characterization of dostarlimab, a therapeutic anti-PD-1
antibody with potent activity to enhance immune function in in vitro
cellular assays and in vivo animal models
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Authors: Sujatha Kumar, Srimoyee Ghosh, Geeta Sharma, Zebin Wang, Marilyn R. Kehry, Margaret H. Marino, Tamlyn Y. Neben, Sharon Lu, Shouqi Luo, Simon Roberts, Sridhar Ramaswamy, Hadi Danaee, David Jenkins
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-27T02:41:13Z
DOI: 10.1080/19420862.2021.1954136
Issue No: Vol. 13, No. 1 (2021)
-
- Characterization of MW06, a human monoclonal antibody with
cross-neutralization activity against both SARS-CoV-2 and SARS-CoV
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Authors: Wen Jiang, Junchao Wang, Shasha Jiao, Chenjian Gu, Wei Xu, Ben Chen, Rongjuan Wang, Huilin Chen, Youhua Xie, An Wang, Gang Li, Dadi Zeng, Jinchao Zhang, Min Zhang, Shuang Wang, Mingzhu Wang, Xun Gui
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-27T02:37:16Z
DOI: 10.1080/19420862.2021.1953683
Issue No: Vol. 13, No. 1 (2021)
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- Highly sensitive detection of antibody nonspecific interactions using flow
cytometry
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Authors: Emily K. Makowski, Lina Wu, Alec A. Desai, Peter M. Tessier
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-27T02:35:26Z
DOI: 10.1080/19420862.2021.1951426
Issue No: Vol. 13, No. 1 (2021)
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- Discovery-stage identification of drug-like antibodies using emerging
experimental and computational methods
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Authors: Emily K. Makowski, Lina Wu, Priyanka Gupta, Peter M. Tessier
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-27T02:31:18Z
DOI: 10.1080/19420862.2021.1895540
Issue No: Vol. 13, No. 1 (2021)
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- Targeting cancer with antibody-drug conjugates: Promises and challenges
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Authors: Alexis Q. Dean, Shen Luo, Julianne D. Twomey, Baolin Zhang
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-22T12:03:11Z
DOI: 10.1080/19420862.2021.1951427
Issue No: Vol. 13, No. 1 (2021)
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- The therapeutic potential of sialylated Fc domains of human IgG
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Authors: Richard J. Pleass
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-07-21T06:09:46Z
DOI: 10.1080/19420862.2021.1953220
Issue No: Vol. 13, No. 1 (2021)
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- Animal- versus in vitro-derived antibodies: avoiding the extremes
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Authors: Andrew R.M. Bradbury, Stefan Dübel, Achim Knappik, Andreas Plückthun
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-20T06:39:05Z
DOI: 10.1080/19420862.2021.1950265
Issue No: Vol. 13, No. 1 (2021)
-
- Challenges of non-clinical safety testing for biologics: A Report of the
9th BioSafe European Annual General Membership Meeting
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Authors: Thomas Kissner, Guenter Blaich, Andreas Baumann, Sven Kronenberg, Adam Hey, Andrea Kiessling, Petra M. Schmitt, Wouter Driessen, Chantal Carrez, Daniel Kramer, Jennifer Fretland, Wolfgang F. Richter, Tobias Paehler, Ulrike Hopfer, Benno Rattel
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-09T01:03:00Z
DOI: 10.1080/19420862.2021.1938796
Issue No: Vol. 13, No. 1 (2021)
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- An integrated approach for characterizing immunogenic responses toward a
bispecific antibody
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Authors: Sivan Cohen, Shan Chung, Christoph Spiess, Victor Lundin, Eric Stefanich, Steven T. Laing, Vanessa Clark, Jochen Brumm, Ying Zhou, Catherine Huang, Joyce Guerrero, Srividya Myneni, Rajbharan Yadav, Ketevan Siradze, Kun Peng
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-06T06:55:04Z
DOI: 10.1080/19420862.2021.1944017
Issue No: Vol. 13, No. 1 (2021)
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- Stability of a high-concentration monoclonal antibody solution produced by
liquid–liquid phase separation
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Authors: Jack E. Bramham, Stephanie A. Davies, Adrian Podmore, Alexander P. Golovanov
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-07-06T06:51:07Z
DOI: 10.1080/19420862.2021.1940666
Issue No: Vol. 13, No. 1 (2021)
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- Correction
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Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-07-06T06:35:06Z
DOI: 10.1080/19420862.2021.1935652
Issue No: Vol. 13, No. 1 (2021)
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- A T cell redirection platform for co-targeting dual antigens on solid
tumors
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Authors: Leonie Enderle, Karim H. Shalaby, Maryna Gorelik, Alexander Weiss, Levi L. Blazer, Marcin Paduch, Lia Cardarelli, Anthony Kossiakoff, Jarrett J. Adams, Sachdev S. Sidhu
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-06-30T10:58:43Z
DOI: 10.1080/19420862.2021.1933690
Issue No: Vol. 13, No. 1 (2021)
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- Identifying biophysical assays and in silico properties that enrich for
slow clearance in clinical-stage therapeutic antibodies
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Authors: Boris Grinshpun, Nels Thorsteinson, Joao NS Pereira, Friedrich Rippmann, David Nannemann, Vanita D. Sood, Yves Fomekong Nanfack
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-06-12T06:50:11Z
DOI: 10.1080/19420862.2021.1932230
Issue No: Vol. 13, No. 1 (2021)
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- A human antibody of potent efficacy against SARS-CoV-2 in rhesus macaques
showed strong blocking activity to B.1.351
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Authors: Chunyin Gu, Xiaodan Cao, Zongda Wang, Xue Hu, Yanfeng Yao, Yiwu Zhou, Peipei Liu, Xiaowu Liu, Ge Gao, Xiao Hu, Yecheng Zhang, Zhen Chen, Li Gao, Yun Peng, Fangfang Jia, Chao Shan, Li Yu, Kunpeng Liu, Nan Li, Weiwei Guo, Guoping Jiang, Juan Min, Jianjian Zhang, Lu Yang, Meng Shi, Tianquan Hou, Yanan Li, Weichen Liang, Guoqiao Lu, Congyi Yang, Yuting Wang, Kaiwen Xia, Zheng Xiao, Jianhua Xue, Xueyi Huang, Xin Chen, Haixia Ma, Donglin Song, Zhongzong Pan, Xueping Wang, Haibing Guo, Hong Liang, Zhiming Yuan, Wuxiang Guan, Su-Jun Deng
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-06-07T07:08:11Z
DOI: 10.1080/19420862.2021.1930636
Issue No: Vol. 13, No. 1 (2021)
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- 501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in
vitro
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Authors: Haolin Liu, Pengcheng Wei, Qianqian Zhang, Zhongzhou Chen, Katja Aviszus, Walter Downing, Shelley Peterson, Lyndon Reynoso, Gregory P. Downey, Stephen K. Frankel, John Kappler, Philippa Marrack, Gongyi Zhang
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-06-02T06:42:43Z
DOI: 10.1080/19420862.2021.1919285
Issue No: Vol. 13, No. 1 (2021)
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- The influence of antibody engineering on Fc conformation and Fc receptor
binding properties: Analysis of FcRn-binding engineered antibodies and an
Fc fusion protein
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Authors: Takuo Suzuki, Noritaka Hashii, Minoru Tada, Akiko Ishii-Watabe
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-05-25T07:24:11Z
DOI: 10.1080/19420862.2021.1923366
Issue No: Vol. 13, No. 1 (2021)
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- Ensembles in solution as a new paradigm for antibody structure prediction
and design
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Authors: Monica L. Fernández-Quintero, Guy Georges, Janos M. Varga, Klaus R. Liedl
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-05-25T07:18:07Z
DOI: 10.1080/19420862.2021.1923122
Issue No: Vol. 13, No. 1 (2021)
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- Potent SARS-CoV-2 binding and neutralization through maturation of iconic
SARS-CoV-1 antibodies
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Authors: Romain Rouet, Ohan Mazigi, Gregory J. Walker, David B. Langley, Meghna Sobti, Peter Schofield, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Jake Y. Henry, Arunasingam Abayasingam, Deborah Burnett, Anthony Kelleher, Robert Brink, Rowena A. Bull, Stuart Turville, Alastair G. Stewart, Christopher C. Goodnow, William D. Rawlinson, Daniel Christ
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-05-24T08:10:22Z
DOI: 10.1080/19420862.2021.1922134
Issue No: Vol. 13, No. 1 (2021)
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- Collecting antibodies and large molecule biomarkers in mouse interstitial
brain fluid: a comparison of microdialysis and cerebral open flow
microperfusion
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Authors: Florie Le Prieult, Erica Barini, Loic Laplanche, Kerstin Schlegel, Mario Mezler
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-05-16T11:40:54Z
DOI: 10.1080/19420862.2021.1918819
Issue No: Vol. 13, No. 1 (2021)
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- Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination
partner for cancer immunotherapy
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Authors: Inja Waldhauer, Valeria Gonzalez-Nicolini, Anne Freimoser-Grundschober, Tapan K Nayak, Linda Fahrni, Ralf J. Hosse, Danny Gerrits, Edwin J. W. Geven, Johannes Sam, Sabine Lang, Esther Bommer, Virginie Steinhart, Elisabeth Husar, Sara Colombetti, Erwin Van Puijenbroek, Markus Neubauer, J. Mark Cline, Pradeep K. Garg, Gregory Dugan, Federica Cavallo, Gonzalo Acuna, Jehad Charo, Volker Teichgräber, Stefan Evers, Otto C. Boerman, Marina Bacac, Ekkehard Moessner, Pablo Umaña, Christian Klein
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-05-11T06:19:48Z
DOI: 10.1080/19420862.2021.1913791
Issue No: Vol. 13, No. 1 (2021)
-
- Animal immunization merges with innovative technologies: A new paradigm
shift in antibody discovery
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Authors: Ponraj Prabakaran, Sambasiva P Rao, Maria Wendt
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-05-05T08:36:47Z
DOI: 10.1080/19420862.2021.1924347
Issue No: Vol. 13, No. 1 (2021)
-
- Targeting cancer homing into the lymph node with a novel anti-CCR7
therapeutic antibody: the paradigm of CLL
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Authors: Carlos Cuesta-Mateos, Raquel Juárez-Sánchez, Tamara Mateu-Albero, Javier Loscertales, Wim Mol, Fernando Terrón, Cecilia Muñoz-Calleja
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-05-04T01:38:45Z
DOI: 10.1080/19420862.2021.1917484
Issue No: Vol. 13, No. 1 (2021)
-
- N-terminal selective conjugation method widens the therapeutic window of
antibody–drug conjugates by improving tolerability and stability
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Authors: Min Ji Ko, Daehae Song, Juhee Kim, Jae Yong Kim, Jaehyun Eom, Byungje Sung, Yong-Gyu Son, Young Min Kim, Sang Hoon Lee, Weon-Kyoo You, Jinwon Jung
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-04-27T09:59:56Z
DOI: 10.1080/19420862.2021.1914885
Issue No: Vol. 13, No. 1 (2021)
-
- A platform-agnostic, function first-based antibody discovery strategy
using plasmid-free mammalian expression of antibodies
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Authors: Ruijun Zhang, Ponraj Prabakaran, Xiaocong Yu, Brian C. Mackness, Ekaterina Boudanova, Joern Hopke, Jose Sancho, Jacqueline Saleh, HyunSuk Cho, Ningning Zhang, Helene Simonds-Mannes, Samuel D. Stimple, Dietmar Hoffmann, Anna Park, Partha S. Chowdhury, Sambasiva P. Rao
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-04-26T06:27:17Z
DOI: 10.1080/19420862.2021.1904546
Issue No: Vol. 13, No. 1 (2021)
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- Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in
gemcitabine-resistant pancreatic cancer models
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Authors: Emilia Rabia, Véronique Garambois, Julie Hubert, Marine Bruciamacchie, Nelly Pirot, Hélène Delpech, Morgane Broyon, Charles Theillet, Pierre-Emmanuel Colombo, Nadia Vie, Diego Tosi, Celine Gongora, Lakhdar Khellaf, Marta Jarlier, Nina Radosevic-Robin, Thierry Chardès, André Pèlegrin, Christel Larbouret
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-04-20T09:33:09Z
DOI: 10.1080/19420862.2021.1914883
Issue No: Vol. 13, No. 1 (2021)
-
- Protective antibodies against human parainfluenza virus type 3 infection
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Authors: Jim Boonyaratanakornkit, Suruchi Singh, Connor Weidle, Justas Rodarte, Ramasamy Bakthavatsalam, Jonathan Perkins, Guillaume B.E. Stewart-Jones, Peter D. Kwong, Andrew T. McGuire, Marie Pancera, Justin J. Taylor
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-04-20T09:24:59Z
DOI: 10.1080/19420862.2021.1912884
Issue No: Vol. 13, No. 1 (2021)
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- Development of a mechanism of action-reflective, dual target cell-based
reporter bioassay for a bispecific monoclonal antibody targeting human
CTLA-4 and PD-1
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Authors: Weimin Chen, Madhu Pandey, Hong Sun, Andrea Rolong, Mingyan Cao, Dengfeng Liu, Jihong Wang, Lingmin Zeng, Alan Hunter, Shihua Lin
Abstract: Volume 13, Issue 1, January-December 2021
.
Citation: mAbs
PubDate: 2021-04-19T06:20:43Z
DOI: 10.1080/19420862.2021.1914359
Issue No: Vol. 13, No. 1 (2021)
-
- Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid
protein
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Authors: Curtis D. Hodge, Daniel. J. Rosenberg, Patricia Grob, Mateusz Wilamowski, Andrzej Joachimiak, Greg L. Hura, Michal Hammel
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-04-12T09:56:13Z
DOI: 10.1080/19420862.2021.1905978
Issue No: Vol. 13, No. 1 (2021)
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- Developments and opportunities in continuous biopharmaceutical
manufacturing
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Authors: Ohnmar Khanal, Abraham M. Lenhoff
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-04-11T05:56:12Z
DOI: 10.1080/19420862.2021.1903664
Issue No: Vol. 13, No. 1 (2021)
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- Calculation of therapeutic antibody viscosity with coarse-grained models,
hydrodynamic calculations and machine learning-based parameters
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Authors: Pin-Kuang Lai, James W. Swan, Bernhardt L. Trout
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-04-09T09:47:34Z
DOI: 10.1080/19420862.2021.1907882
Issue No: Vol. 13, No. 1 (2021)
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- TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine
release in preclinical models of B-NHL
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Authors: Harbani K. Malik-Chaudhry, Kirthana Prabhakar, Harshad S. Ugamraj, Andrew A. Boudreau, Benjamin Buelow, Kevin Dang, Laura M. Davison, Katherine E. Harris, Brett Jorgensen, Heather Ogana, Duy Pham, Ute Schellenberger, Wim Van Schooten, Roland Buelow, Suhasini Iyer, Nathan D. Trinklein, Udaya S. Rangaswamy
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-04-05T05:46:12Z
DOI: 10.1080/19420862.2021.1890411
Issue No: Vol. 13, No. 1 (2021)
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- A bivalent, bispecific Dab-Fc antibody molecule for dual targeting of HER2
and HER3
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Authors: Alexander Rau, Katharina Kocher, Mirjam Rommel, Lennart Kühl, Maximilian Albrecht, Hannes Gotthard, Nadine Aschmoneit, Bettina Noll, Monilola A. Olayioye, Roland E. Kontermann, Oliver Seifert
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-03-23T04:57:43Z
DOI: 10.1080/19420862.2021.1902034
Issue No: Vol. 13, No. 1 (2021)
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- Immunogenicity risk assessment for biotherapeutics through in vitro
detection of CD134 and CD137 on T helper cells
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Authors: Sivan Cohen, Srividya Myneni, Anna Batt, Joyce Guerrero, Jochen Brumm, Shan Chung
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-03-17T09:04:10Z
DOI: 10.1080/19420862.2021.1898831
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- Data mining patented antibody sequences
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Authors: Konrad Krawczyk, Andrew Buchanan, Paolo Marcatili
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-03-16T06:30:00Z
DOI: 10.1080/19420862.2021.1892366
Issue No: Vol. 13, No. 1 (2021)
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- Functional GLP-1R antibodies identified from a synthetic GPCR-focused
library demonstrate potent blood glucose control
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Authors: Qiang Liu, Pankaj Garg, Burcu Hasdemir, Linya Wang, Emily Tuscano, Emily Sever, Erica Keane, Ana G Lujan Hernandez, Tom Z. Yuan, Eric Kwan, Joyce Lai, Greg Szot, Sreenivasan Paruthiyil, Fumiko Axelrod, Aaron K. Sato
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-03-12T09:01:22Z
DOI: 10.1080/19420862.2021.1893425
Issue No: Vol. 13, No. 1 (2021)
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- Extended plasma half-life of albumin-binding domain fused human IgA upon
pH-dependent albumin engagement of human FcRn in vitro and in vivo
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Authors: Simone Mester, Mitchell Evers, Saskia Meyer, Jeannette Nilsen, Victor Greiff, Inger Sandlie, Jeanette Leusen, Jan Terje Andersen
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-03-11T06:02:25Z
DOI: 10.1080/19420862.2021.1893888
Issue No: Vol. 13, No. 1 (2021)
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- Fc galactosylation follows consecutive reaction kinetics and enhances
immunoglobulin G hexamerization for complement activation
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Authors: Bingchuan Wei, Xuan Gao, Lance Cadang, Saeed Izadi, Peilu Liu, Hui-Min Zhang, Elizabeth Hecht, Jeongsup Shim, Gordon Magill, Juan Rincon Pabon, Lu Dai, Wilson Phung, Elaine Lin, Christopher Wang, Kevin Whang, Sean Sanchez, Jose Oropeza Jr, Julien Camperi, Jennifer Zhang, Wendy Sandoval, Yonghua Taylor Zhang, Guoying Jiang
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-03-08T01:20:55Z
DOI: 10.1080/19420862.2021.1893427
Issue No: Vol. 13, No. 1 (2021)
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- Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing
Spike epitopes demonstrate enhanced potency against SARS-CoV-2
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Authors: Shion A. Lim, Josef A. Gramespacher, Katarina Pance, Nicholas J. Rettko, Paige Solomon, Jing Jin, Irene Lui, Susanna K. Elledge, Jia Liu, Colton J. Bracken, Graham Simmons, Xin X. Zhou, Kevin K. Leung, James A. Wells
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-03-05T11:45:27Z
DOI: 10.1080/19420862.2021.1893426
Issue No: Vol. 13, No. 1 (2021)
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- Identification of critical chemical modifications and paratope mapping by
size exclusion chromatography of stressed antibody-target complexes
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Authors: Pavel V. Bondarenko, Andrew C. Nichols, Gang Xiao, Rachel Liuqing Shi, Pik Kay Chan, Thomas M Dillon, Fernando Garces, David J. Semin, Margaret S. Ricci
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-02-21T03:08:48Z
DOI: 10.1080/19420862.2021.1887629
Issue No: Vol. 13, No. 1 (2021)
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- Identification of critical chemical modifications by size exclusion
chromatography of stressed antibody-target complexes with competitive
binding
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Authors: Rachel Liuqing Shi, Gang Xiao, Thomas M. Dillon, Arnold McAuley, Margaret S. Ricci, Pavel V. Bondarenko
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-02-21T02:58:09Z
DOI: 10.1080/19420862.2021.1887612
Issue No: Vol. 13, No. 1 (2021)
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- Coming together at the hinges: Therapeutic prospects of IgG3
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Authors: Thach H. Chu, Edward F. Patz, Margaret E. Ackerman
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-02-19T08:44:23Z
DOI: 10.1080/19420862.2021.1882028
Issue No: Vol. 13, No. 1 (2021)
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- Off-target binding of an anti-amyloid beta monoclonal antibody to platelet
factor 4 causes acute and chronic toxicity in cynomolgus monkeys
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Authors: Lise I. Loberg, Meha Chhaya, Alexander Ibraghimov, Edit Tarcsa, Andreas Striebinger, Andreas Popp, Lili Huang, Frank Oellien, Stefan Barghorn
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-02-18T07:20:38Z
DOI: 10.1080/19420862.2021.1887628
Issue No: Vol. 13, No. 1 (2021)
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- Combining random mutagenesis, structure-guided design and next-generation
sequencing to mitigate polyreactivity of an anti-IL-21R antibody
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Authors: Sharon M. Campbell, Joseph DeBartolo, James R. Apgar, Lydia Mosyak, Virginie McManus, Sonia Beyer, Eric M. Bennett, Matthew Lambert, Orla Cunningham
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-02-09T08:56:43Z
DOI: 10.1080/19420862.2021.1883239
Issue No: Vol. 13, No. 1 (2021)
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- One size does not fit all: navigating the multi-dimensional space to
optimize T-cell engaging protein therapeutics
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Authors: Wei Chen, Fan Yang, Carole Wang, Jatin Narula, Edward Pascua, Irene Ni, Sheng Ding, Xiaodi Deng, Matthew Ling-Hon Chu, Amber Pham, Xiaoyue Jiang, Kevin C. Lindquist, Patrick J. Doonan, Tom Van Blarcom, Yik Andy Yeung, Javier Chaparro-Riggers
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-02-09T08:44:22Z
DOI: 10.1080/19420862.2020.1871171
Issue No: Vol. 13, No. 1 (2021)
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- Innovative approaches to biologic development on the trail of CT-P13:
biosimilars, value-added medicines, and biobetters
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Authors: HoUng Kim, Rieke Alten, Fraser Cummings, Silvio Danese, Geert D’Haens, Paul Emery, Subrata Ghosh, Cyrielle Gilletta de Saint Joseph, JongHyuk Lee, James O. Lindsay, Elena Nikiphorou, Ben Parker, Stefan Schreiber, Steven Simoens, Rene Westhovens, Ji Hoon Jeong, Laurent Peyrin-Biroulet
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-02-09T06:20:46Z
DOI: 10.1080/19420862.2020.1868078
Issue No: Vol. 13, No. 1 (2021)
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- Brain pharmacokinetics of anti-transferrin receptor antibody affinity
variants in rats determined using microdialysis
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Authors: Hsueh-Yuan Chang, Shengjia Wu, Yingyi Li, Wanying Zhang, Matthew Burrell, Carl I. Webster, Dhaval K. Shah
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-27T07:32:35Z
DOI: 10.1080/19420862.2021.1874121
Issue No: Vol. 13, No. 1 (2021)
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- Common light chain chickens produce human antibodies of high affinity and
broad epitope coverage for the engineering of bispecifics
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Authors: Kathryn H. Ching, Kimberley Berg, Kevin Reynolds, Darlene Pedersen, Alba Macias, Yasmina N. Abdiche, William D. Harriman, Philip A. Leighton
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-25T12:51:22Z
DOI: 10.1080/19420862.2020.1862451
Issue No: Vol. 13, No. 1 (2021)
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- Bispecific antibody target pair discovery by high-throughput phenotypic
screening using in vitro combinatorial Fab libraries
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Authors: Pallavi Bhatta, Kevin D. Whale, Amy K. Sawtell, Clare L. Thompson, Stephen E. Rapecki, David A. Cook, Breda M. Twomey, Milena Mennecozzi, Laura E. Starkie, Emily M. C. Barry, Shirley J. Peters, Ahmad M. Kamal, Helene M. Finney
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-25T09:37:22Z
DOI: 10.1080/19420862.2020.1859049
Issue No: Vol. 13, No. 1 (2021)
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- Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific
antibody for the treatment of solid tumors
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Authors: Adam R. Root, Gurkan Guntas, Madan Katragadda, James R. Apgar, Jatin Narula, Chew Shun Chang, Sara Hanscom, Matthew McKenna, Jason Wade, Caryl Meade, Weijun Ma, Yongjing Guo, Yan Liu, Weili Duan, Claire Hendershot, Amy C. King, Yan Zhang, Eric Sousa, Amy Tam, Susan Benard, Han Yang, Kerry Kelleher, Fang Jin, Nicole Piche-Nicholas, Sinead E. Keating, Fernando Narciandi, Rosemary Lawrence-Henderson, Maya Arai, Wayne R. Stochaj, Kristine Svenson, Lidia Mosyak, Khetemcnee Lam, Christopher Francis, Kimberly Marquette, Liliana Wroblewska, H. Lily Zhu, Alfredo Darmanin Sheehan, Edward R. LaVallie, Aaron M. D’Antona, Alison Betts, Lindsay King, Edward Rosfjord, Orla Cunningham, Laura Lin, Puja Sapra, Lioudmila Tchistiakova, Divya Mathur, Laird Bloom
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-18T10:33:21Z
DOI: 10.1080/19420862.2020.1850395
Issue No: Vol. 13, No. 1 (2021)
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- Antibodies to watch in 2021
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Authors: Hélène Kaplon, Janice M. Reichert
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-18T06:54:28Z
DOI: 10.1080/19420862.2020.1860476
Issue No: Vol. 13, No. 1 (2021)
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- Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the
same epitope
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Authors: Wing Ki Wong, Sarah A. Robinson, Alexander Bujotzek, Guy Georges, Alan P. Lewis, Jiye Shi, James Snowden, Bruck Taddese, Charlotte M. Deane
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-15T10:03:52Z
DOI: 10.1080/19420862.2021.1873478
Issue No: Vol. 13, No. 1 (2021)
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- In memoriam: Jefferson Foote
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Authors: E. Sally Ward, Peter Jones, Tim Buss, Cristina Rada, Gregory Winter, Richard Willson
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-13T06:15:48Z
DOI: 10.1080/19420862.2020.1870059
Issue No: Vol. 13, No. 1 (2021)
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- A computational method for immune repertoire mining that identifies novel
binders from different clonotypes, demonstrated by identifying
anti-pertussis toxoid antibodies
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Authors: Eve Richardson, Jacob D. Galson, Paul Kellam, Dominic F. Kelly, Sarah E. Smith, Anne Palser, Simon Watson, Charlotte M. Deane
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-11T02:33:14Z
DOI: 10.1080/19420862.2020.1869406
Issue No: Vol. 13, No. 1 (2021)
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- Antibody-mediated delivery of LIGHT to the tumor boosts natural killer
cells and delays tumor progression
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Authors: Marco Stringhini, Jacqueline Mock, Vanessa Fontana, Patrizia Murer, Dario Neri
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-06T02:02:23Z
DOI: 10.1080/19420862.2020.1868066
Issue No: Vol. 13, No. 1 (2021)
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- Rational selection of building blocks for the assembly of bispecific
antibodies
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Authors: Danyang Gong, Timothy P. Riley, Krzysztof P. Bzymek, Ana R. Correia, Danqing Li, Christopher Spahr, John H. Robinson, Ryan B. Case, Zhulun Wang, Fernando Garces
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-05T08:01:15Z
DOI: 10.1080/19420862.2020.1870058
Issue No: Vol. 13, No. 1 (2021)
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- Activity of murine surrogate antibodies for durvalumab and tremelimumab
lacking effector function and the ability to deplete regulatory T cells in
mouse models of cancer
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Authors: Darren J. Schofield, Jennifer Percival-Alwyn, Mateusz Rytelewski, John Hood, Raymond Rothstein, Leslie Wetzel, Kelly McGlinchey, Grace Adjei, Amanda Watkins, LeeAnn Machiesky, Weimin Chen, John Andrews, Maria Groves, Michelle Morrow, Ross A. Stewart, Andrew Leinster, Robert W. Wilkinson, Scott A. Hammond, Nadia Luheshi, Claire Dobson, Michael Oberst
Abstract: Volume 13, Issue 1, January-December 2021
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Citation: mAbs
PubDate: 2021-01-05T07:59:05Z
DOI: 10.1080/19420862.2020.1857100
Issue No: Vol. 13, No. 1 (2021)
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