Subjects -> MEDICAL SCIENCES (Total: 8669 journals)
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CARDIOVASCULAR DISEASES (338 journals)                  1 2 | Last

Showing 1 - 200 of 338 Journals sorted alphabetically
Acta Angiologica     Open Access   (Followers: 5)
Acta Cardiologica     Hybrid Journal   (Followers: 2)
Acute Cardiac Care     Hybrid Journal   (Followers: 8)
Adipositas - Ursachen, Folgeerkrankungen, Therapie     Hybrid Journal  
AJP Heart and Circulatory Physiology     Hybrid Journal   (Followers: 12)
Aktuelle Kardiologie     Hybrid Journal   (Followers: 1)
American Heart Journal     Hybrid Journal   (Followers: 60)
American Journal of Cardiology     Hybrid Journal   (Followers: 68)
American Journal of Cardiovascular Drugs     Hybrid Journal   (Followers: 18)
American Journal of Hypertension     Hybrid Journal   (Followers: 29)
Anales de Cirugia Vascular     Full-text available via subscription   (Followers: 1)
Anatolian Journal of Cardiology     Open Access   (Followers: 6)
Angiología     Full-text available via subscription  
Angiologia e Cirurgia Vascular     Open Access   (Followers: 1)
Angiology     Hybrid Journal   (Followers: 3)
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (Followers: 1)
Annals of Circulation     Open Access   (Followers: 2)
Annals of Noninvasive Electrocardiology     Hybrid Journal   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 12)
AORTA     Open Access  
Archives of Cardiovascular Diseases     Full-text available via subscription   (Followers: 6)
Archives of Cardiovascular Diseases Supplements     Full-text available via subscription   (Followers: 4)
Archives of Cardiovascular Imaging     Open Access   (Followers: 2)
Archivos de cardiología de México     Open Access   (Followers: 1)
Argentine Journal of Cardiology (English edition)     Open Access   (Followers: 2)
Arquivos Brasileiros de Cardiologia     Open Access   (Followers: 2)
Arrhythmia & Electrophysiology Review     Open Access   (Followers: 1)
Arteriosclerosis, Thrombosis and Vascular Biology     Full-text available via subscription   (Followers: 33)
Artery Research     Hybrid Journal   (Followers: 5)
ARYA Atherosclerosis     Open Access  
ASAIO Journal     Hybrid Journal   (Followers: 4)
ASEAN Heart Journal     Open Access   (Followers: 3)
Asian Cardiovascular and Thoracic Annals     Hybrid Journal   (Followers: 2)
Aswan Heart Centre Science & Practice Services     Open Access   (Followers: 1)
Atherosclerosis : X     Open Access  
Bangladesh Heart Journal     Open Access   (Followers: 3)
Basic Research in Cardiology     Hybrid Journal   (Followers: 9)
BMC Cardiovascular Disorders     Open Access   (Followers: 22)
Brain Circulation     Open Access   (Followers: 1)
British Journal of Cardiology     Full-text available via subscription   (Followers: 18)
Canadian Journal of Cardiology     Hybrid Journal   (Followers: 18)
Cardiac Cath Lab Director     Full-text available via subscription  
Cardiac Electrophysiology Review     Hybrid Journal   (Followers: 2)
Cardiac Failure Review     Open Access   (Followers: 2)
Cardiocore     Full-text available via subscription   (Followers: 1)
Cardiogenetics     Open Access   (Followers: 3)
Cardiology     Full-text available via subscription   (Followers: 20)
Cardiology and Angiology: An International Journal     Open Access   (Followers: 1)
Cardiology and Therapy     Open Access   (Followers: 11)
Cardiology Clinics     Full-text available via subscription   (Followers: 14)
Cardiology in Review     Hybrid Journal   (Followers: 9)
Cardiology in the Young     Hybrid Journal   (Followers: 35)
Cardiology Journal     Open Access   (Followers: 6)
Cardiology Plus     Open Access   (Followers: 1)
Cardiology Research     Open Access   (Followers: 15)
Cardiology Research and Practice     Open Access   (Followers: 11)
Cardiopulmonary Physical Therapy Journal     Hybrid Journal   (Followers: 9)
Cardiorenal Medicine     Full-text available via subscription   (Followers: 1)
Cardiothoracic Surgeon     Open Access   (Followers: 1)
CardioVasc     Full-text available via subscription   (Followers: 1)
Cardiovascular & Haematological Disorders - Drug Targets     Hybrid Journal   (Followers: 1)
Cardiovascular & Hematological Agents in Medicinal Chemistry     Hybrid Journal   (Followers: 2)
CardioVascular and Interventional Radiology     Hybrid Journal   (Followers: 15)
Cardiovascular and Thoracic Open     Open Access  
Cardiovascular Diabetology     Open Access   (Followers: 10)
Cardiovascular Drugs and Therapy     Hybrid Journal   (Followers: 14)
Cardiovascular Endocrinology & Metabolism     Hybrid Journal   (Followers: 1)
Cardiovascular Engineering     Hybrid Journal   (Followers: 1)
Cardiovascular Engineering and Technology     Hybrid Journal   (Followers: 1)
Cardiovascular Intervention and Therapeutics     Hybrid Journal   (Followers: 5)
Cardiovascular Journal     Open Access   (Followers: 6)
Cardiovascular Journal of Africa     Full-text available via subscription   (Followers: 5)
Cardiovascular Journal of South Africa     Full-text available via subscription   (Followers: 2)
Cardiovascular Medicine in General Practice     Full-text available via subscription   (Followers: 7)
Cardiovascular Pathology     Hybrid Journal   (Followers: 4)
Cardiovascular Regenerative Medicine     Open Access  
Cardiovascular Research     Hybrid Journal   (Followers: 16)
Cardiovascular Revascularization Medicine     Hybrid Journal   (Followers: 1)
Cardiovascular System     Open Access  
Cardiovascular Therapeutics     Open Access   (Followers: 1)
Cardiovascular Toxicology     Hybrid Journal   (Followers: 6)
Cardiovascular Ultrasound     Open Access   (Followers: 5)
Case Reports in Cardiology     Open Access   (Followers: 7)
Catheterization and Cardiovascular Interventions     Hybrid Journal   (Followers: 3)
Cerebrovascular Diseases     Full-text available via subscription   (Followers: 3)
Cerebrovascular Diseases Extra     Open Access  
Chest     Full-text available via subscription   (Followers: 103)
Choroby Serca i Naczyń     Open Access   (Followers: 1)
Circulation     Hybrid Journal   (Followers: 267)
Circulation : Cardiovascular Imaging     Hybrid Journal   (Followers: 15)
Circulation : Cardiovascular Interventions     Hybrid Journal   (Followers: 19)
Circulation : Cardiovascular Quality and Outcomes     Hybrid Journal   (Followers: 11)
Circulation : Genomic and Precision Medicine     Hybrid Journal   (Followers: 16)
Circulation : Heart Failure     Hybrid Journal   (Followers: 26)
Circulation Research     Hybrid Journal   (Followers: 35)
Cirugía Cardiovascular     Open Access  
Clínica e Investigación en Arteriosclerosis     Full-text available via subscription  
Clínica e Investigación en arteriosclerosis (English Edition)     Hybrid Journal  
Clinical and Experimental Hypertension     Hybrid Journal   (Followers: 3)
Clinical Cardiology     Hybrid Journal   (Followers: 10)
Clinical Hypertension     Open Access   (Followers: 5)
Clinical Medicine Insights : Cardiology     Open Access   (Followers: 6)
Clinical Research in Cardiology     Hybrid Journal   (Followers: 5)
Clinical Research in Cardiology Supplements     Hybrid Journal  
Clinical Trials and Regulatory Science in Cardiology     Open Access   (Followers: 4)
Congenital Heart Disease     Hybrid Journal   (Followers: 6)
Congestive Heart Failure     Hybrid Journal   (Followers: 4)
Cor et Vasa     Full-text available via subscription   (Followers: 1)
Coronary Artery Disease     Hybrid Journal   (Followers: 3)
CorSalud     Open Access  
Critical Pathways in Cardiology     Hybrid Journal   (Followers: 5)
Current Cardiology Reports     Hybrid Journal   (Followers: 6)
Current Cardiology Reviews     Hybrid Journal   (Followers: 3)
Current Cardiovascular Imaging Reports     Hybrid Journal   (Followers: 1)
Current Cardiovascular Risk Reports     Hybrid Journal  
Current Heart Failure Reports     Hybrid Journal   (Followers: 5)
Current Hypertension Reports     Hybrid Journal   (Followers: 6)
Current Hypertension Reviews     Hybrid Journal   (Followers: 6)
Current Opinion in Cardiology     Hybrid Journal   (Followers: 13)
Current Problems in Cardiology     Hybrid Journal   (Followers: 3)
Current Research : Cardiology     Full-text available via subscription   (Followers: 1)
Current Treatment Options in Cardiovascular Medicine     Hybrid Journal   (Followers: 1)
Current Vascular Pharmacology     Hybrid Journal   (Followers: 5)
CVIR Endovascular     Open Access   (Followers: 1)
Der Kardiologe     Hybrid Journal   (Followers: 1)
Echo Research and Practice     Open Access   (Followers: 2)
Echocardiography     Hybrid Journal   (Followers: 4)
Egyptian Heart Journal     Open Access   (Followers: 2)
Egyptian Journal of Cardiothoracic Anesthesia     Open Access  
ESC Heart Failure     Open Access   (Followers: 4)
European Cardiology Review     Open Access   (Followers: 1)
European Heart Journal     Hybrid Journal   (Followers: 67)
European Heart Journal - Cardiovascular Imaging     Hybrid Journal   (Followers: 10)
European Heart Journal - Cardiovascular Pharmacotherapy     Full-text available via subscription   (Followers: 2)
European Heart Journal - Quality of Care and Clinical Outcomes     Hybrid Journal  
European Heart Journal : Acute Cardiovascular Care     Hybrid Journal   (Followers: 1)
European Heart Journal : Case Reports     Open Access   (Followers: 1)
European Heart Journal Supplements     Hybrid Journal   (Followers: 7)
European Journal of Cardio-Thoracic Surgery     Hybrid Journal   (Followers: 9)
European Journal of Cardio-Thoracic Surgery Supplements     Full-text available via subscription   (Followers: 2)
European Journal of Cardiovascular Nursing     Hybrid Journal   (Followers: 5)
European Journal of Heart Failure     Hybrid Journal   (Followers: 13)
European Journal of Preventive Cardiology.     Hybrid Journal   (Followers: 6)
European Stroke Organisation     Hybrid Journal   (Followers: 3)
Experimental & Translational Stroke Medicine     Open Access   (Followers: 9)
Expert Review of Cardiovascular Therapy     Full-text available via subscription   (Followers: 3)
Folia Cardiologica     Open Access  
Forum Zaburzeń Metabolicznych     Hybrid Journal  
Frontiers in Cardiovascular Medicine     Open Access   (Followers: 1)
Future Cardiology     Hybrid Journal   (Followers: 5)
General Thoracic and Cardiovascular Surgery     Hybrid Journal   (Followers: 3)
Global Cardiology Science and Practice     Open Access   (Followers: 5)
Global Heart     Hybrid Journal   (Followers: 3)
Heart     Hybrid Journal   (Followers: 48)
Heart and Mind     Open Access  
Heart and Vessels     Hybrid Journal  
Heart Failure Clinics     Full-text available via subscription   (Followers: 2)
Heart Failure Reviews     Hybrid Journal   (Followers: 3)
Heart India     Open Access   (Followers: 2)
Heart International     Full-text available via subscription  
Heart Rhythm     Hybrid Journal   (Followers: 11)
Heart Views     Open Access   (Followers: 2)
HeartRhythm Case Reports     Open Access  
Hellenic Journal of Cardiology     Open Access   (Followers: 1)
Herz     Hybrid Journal   (Followers: 2)
High Blood Pressure & Cardiovascular Prevention     Full-text available via subscription   (Followers: 2)
Hypertension     Full-text available via subscription   (Followers: 23)
Hypertension     Open Access   (Followers: 2)
Hypertension in Pregnancy     Hybrid Journal   (Followers: 9)
Hypertension Research     Hybrid Journal   (Followers: 4)
Ibrahim Cardiac Medical Journal     Open Access  
IJC Heart & Vessels     Open Access   (Followers: 1)
IJC Heart & Vasculature     Open Access   (Followers: 1)
IJC Metabolic & Endocrine     Open Access   (Followers: 1)
Indian Heart Journal     Open Access   (Followers: 5)
Indian Journal of Cardiovascular Disease in Women WINCARS     Open Access  
Indian Journal of Thoracic and Cardiovascular Surgery     Hybrid Journal  
Indian Pacing and Electrophysiology Journal     Open Access   (Followers: 1)
Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery     Hybrid Journal   (Followers: 1)
Insuficiencia Cardíaca     Open Access  
Interactive CardioVascular and Thoracic Surgery     Hybrid Journal   (Followers: 7)
International Cardiovascular Forum Journal     Open Access  
International Journal of Angiology     Hybrid Journal   (Followers: 2)
International Journal of Cardiology     Hybrid Journal   (Followers: 17)
International Journal of Cardiology Hypertension     Open Access   (Followers: 1)
International Journal of Cardiovascular and Cerebrovascular Disease     Open Access   (Followers: 3)
International Journal of Cardiovascular Imaging     Hybrid Journal   (Followers: 2)
International Journal of Cardiovascular Research     Hybrid Journal   (Followers: 6)
International Journal of Heart Rhythm     Open Access  
International Journal of Hypertension     Open Access   (Followers: 8)
International Journal of Hyperthermia     Open Access  
International Journal of Stroke     Hybrid Journal   (Followers: 32)
International Journal of the Cardiovascular Academy     Open Access  
Interventional Cardiology Clinics     Full-text available via subscription   (Followers: 2)
Interventional Cardiology Review     Open Access  
JACC : Basic to Translational Science     Open Access   (Followers: 5)
JACC : Cardiovascular Imaging     Hybrid Journal   (Followers: 18)
JACC : Cardiovascular Interventions     Hybrid Journal   (Followers: 19)
JACC : Heart Failure     Full-text available via subscription   (Followers: 14)
JAMA Cardiology     Hybrid Journal   (Followers: 30)

        1 2 | Last

Similar Journals
Journal Cover
Current Cardiovascular Imaging Reports
Journal Prestige (SJR): 0.34
Citation Impact (citeScore): 1
Number of Followers: 1  
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 1941-9074 - ISSN (Online) 1941-9066
Published by Springer-Verlag Homepage  [2626 journals]
  • Coronary Computed Tomography Angiography Improving Outcomes in Patients
           with Chest Pain
    • Abstract: Purpose of Review To provide an overview of recent studies of coronary computed tomography angiography (CCTA) and how it has helped to improve clinical outcomes for patients presenting with chest pain. Recent Findings Randomised controlled trials have uniformly demonstrated that the use of CCTA is associated with improvements in patient diagnosis, management and treatments as well as the avoidance of unnecessary invasive coronary angiography. These changes have been associated with consistent reductions in long-term rates of fatal or non-fatal myocardial infarction. Summary Major beneficial effects in clinical management and patient outcomes are seen with the use of coronary computed tomography angiography. CCTA might be considered to be the first test of choice for the investigation of coronary heart disease.
      PubDate: 2019-03-22
  • Artificial Intelligence in Nuclear Cardiology: Adding Value to
    • Abstract: Purpose of the Review Radionuclide myocardial perfusion imaging (MPI) continues to be an accurate and reproducible method of diagnosing obstructive coronary artery disease (CAD) with predictive, prognostic, and economic value. We review the evolutionary potential of machine learning (ML), a subset of artificial intelligence, as an adjunct to MPI. Recent Findings Applying the broad scope of ML, including the integration of deep learning, can leverage the knowledge representation and automated reasoning to detect and extrapolate patterns from high-dimensional features of MPI. There is growing evidence to suggest superior abilities of ML over parametric statistical models for predicting the presence of obstructive CAD, the need for revascularization, and the occurrence of major adverse cardiac events including cardiac death. Summary ML is uniquely positioned to provide the next great advancement in the field of nuclear cardiology for improving patient-specific risk stratification.
      PubDate: 2019-03-19
  • CMR in Transcatheter Valve Interventions: State of the Art and Future
    • Abstract: Purpose of Review Transcatheter valve interventions require careful planning and rely heavily on multimodality imaging. In contrast to echocardiography and computed tomography cardiovascular magnetic resonance (CMR) remains underused in clinical practice. Recent Findings CMR techniques such as multiplanar cine imaging unlimited by echo windows or ionizing radiation exposure, quantification of flow, and advanced tissue characterization have the potential to add valuable complimentary information to the evaluation of patients with valvular heart disease. Summary In this paper, we review the evidence for CMR to guide transcatheter valve interventions with a focus on practical applications for the interventionist.
      PubDate: 2019-03-01
  • Choosing the Appropriate Stress Test for Myocardial Perfusion Imaging
    • Abstract: Purpose of Review Choosing the most appropriate test or protocol to ensure patient safety along with accurate and informative results can be challenging. The aim of this article is to review important considerations when choosing a nuclear stress perfusion study. Recent Findings Single-photon emission computed tomography (SPECT) has a sensitivity of 70% and a specificity of 78% for the diagnosis of coronary artery disease (CAD), and positron emission tomography (PET) has a sensitivity of 90% and specificity of 88%. The addition of either SPECT or PET to cardiac-gated computed tomography (CCTA) confers an increase in specificity when compared to CCTA alone, at the cost of a lower sensitivity. Summary SPECT sets itself aside because of its relative low cost and easy accessibility. PET has a superior diagnostic performance and lower radiation exposure, but is less available and relatively more expensive for most clinicians. When ordering a nuclear stress perfusion test, the type of protocol and radiotracers used should be tailored to achieve the best overall accuracy and prognostic assessment with the lowest radiation dose achievable.
      PubDate: 2019-02-28
  • Molecular Imaging to Monitor Left Ventricular Remodeling in Heart Failure
    • Abstract: Purpose of Review Cardiovascular diseases are the leading cause of deaths worldwide. Many complex cellular and molecular pathways lead to myocardial remodeling after ischemic insults. Anatomy, function, and viability of the myocardium can be assessed by modern medical imaging techniques by both visualizing and quantifying damages. Novel imaging techniques aim for a precise and accurate visualization of the myocardium and for the detection of alternations at the molecular level. Recent Findings Magnetic resonance imaging assesses anatomy, function, and tissue characterization of the myocardium non-invasively with high spatial resolution, sensitivity, and specificity. Using hyperpolarized magnetic resonance imaging, molecular and metabolic conditions can be assessed non-invasively. Single photon-emission tomography and positron-emission tomography are the most sensitive techniques to detect biological processes in the myocardium. Cardiac perfusion, metabolism, and viability are the most common clinical targets. In addition, molecular-targeted imaging of biological processes involved in heart failure, such as myocardial innervation, inflammation, and extracellular matrix remodeling, is feasible. Summary Novel imaging techniques can provide a precise and accurate visualization of the myocardium and for the detection of alternations at molecular level.
      PubDate: 2019-02-26
  • Advances in PET Imaging of Sarcoidosis
    • Abstract: Purpose of Review The purpose of this paper is to provide an updated review of recent advances in protocols for positron emission tomography (PET) or PET/computed tomography (PET/CT) imaging in patients with sarcoidosis. Recent Findings There has been more research focused on developing newer and improved PET imaging modalities to diagnose and follow-up cardiac sarcoidosis (CS). Fluorine-18-fluorodeoxyglucose (18F- FDG)-PET are widely used to diagnose CS, with or without concurrent rest nuclear myocardial perfusion study. There have been various patient preparation strategies for FDG PET/CT in CS. Interpretation criteria for cardiac FDG PET/CT in diagnosing CS also varies. There are emerging data utilizing new PET radiotracers (i.e., 68Ga-DOTATATE, 18F-Flurpiridaz) and PET/MRI imaging for CS diagnosis. Summary Based on published imaging data, patient preparation with a 72-h high-fat, high-protein, and very-low-carbohydrate diet protocol generates the most promising results in suppression of physiological myocardial FDG uptake in cardiac PET/CT. The “focal-on-diffuse uptake” pattern on myocardial uptake is not convincing and should not be interpreted as active CS. Nuclear myocardial perfusion test might not be needed to diagnose CS if optimal suppression of myocardial background uptake of FDG is achieved. FDG PET/MRI with optimal patient preparation may increase diagnostic confidence. More data will be needed for new tracers to be used for CS diagnosis.
      PubDate: 2019-02-14
  • Contemporary Issues in Quantitative Myocardial Perfusion CMR Imaging
    • Abstract: Purpose of Review This review highlights the development and application of quantitative myocardial perfusion by cardiac magnetic resonance (CMR) and discusses recent innovations in this area. Recent Findings First pass, contrast-enhanced CMR can accurately quantify myocardial perfusion in order to diagnose obstructive coronary artery disease and microvascular dysfunction. Quantitative analysis conveys additional prognostic information beyond other CMR findings. New, fully automated techniques may aid standardization of methods across centers. Summary CMR quantitative perfusion has robust performance for the diagnosis of obstructive coronary disease and microvascular dysfunction and conveys prognostic information. Adoption of automated post-processing and standardized protocols will further strengthen CMR in its position as the modality of choice for the evaluation of possible myocardial ischemia.
      PubDate: 2019-02-14
  • Plaque Assessment on Serial Coronary CTA
    • Abstract: Purpose of Review This review addresses the role of serial coronary computed tomography angiography (CTA) on the evaluation of atherosclerosis progression, risk stratification, and targeting individual pharmacotherapy. Recent Findings The presence, extent, and severity of coronary artery disease (CAD) detected by coronary CTA are associated with an adverse prognosis. Similarly, the presence of high-risk plaque features such as positive remodeling, low-attenuation plaque, spotty calcifications, and napkin-ring sign are associated with major adverse cardiac events. More recently, examinations using serial coronary CTA have also shown that these static CTA plaque features are associated with a more rapid progression of atherosclerosis on follow-up imaging and may identify a subset of patients at increased risk for plaque rupture. While the impact of serial CTA findings on management and hard outcomes remains a topic of ongoing investigation, available data supports the ability of statin therapy to reduce CTA-identified plaque burden and modify plaque composition. Summary Coronary CTA identifies various plaque features associated with an increased risk of plaque progression and adverse cardiac events. Available data support the use of CTA to individualize statin therapy and utilize serial CTA imaging to study the impact of pharmacotherapy on plaque burden and outcomes.
      PubDate: 2019-02-14
  • Radionuclide Imaging in Chagas Cardiomyopathy
    • Abstract: Purpose of Review To review the contributions of radionuclide imaging to understanding the manifestations and pathophysiology of chronic Chagas cardiomyopathy (CCC). Recent Findings Experimental studies using high-resolution SPECT myocardial perfusion imaging (MPI) show that myocardial perfusion derangement that corresponds to dysfunctional, viable myocardium is closely linked to inflammation and precedes LV regional systolic dysfunction. Clinical studies show that microvascular ischemia is strictly related to the areas of cardiac sympathetic denervation, assessed by 123I-MIBG imaging, which correlates with severe ventricular arrhythmia incidence. Initial case reports suggest that 18F-FDG-PET imaging is a promising, non-invasive detection method for myocardial inflammation. Summary Available evidence indicates that microvascular ischemia participates in the mechanisms causing myocardial injury in CCC, with potential implication for monitoring subclinical disease progression. Moreover, MIBG imaging is a promising tool for risk stratification of sudden death. Preliminary clinical experience suggests a role for 18F-FDG-PET in detection of inflammation in CCC.
      PubDate: 2019-02-12
  • Advances in Real-Time MRI–Guided Electrophysiology
    • Abstract: Purpose of Review Theoretical benefits of real-time MRI guidance over conventional electrophysiology include contemporaneous 3D substrate assessment and accurate intra-procedural guidance and evaluation of ablation lesions. We review the unique challenges inherent to MRI-guided electrophysiology and how to translate the potential benefits in the treatment of cardiac arrhythmias. Recent Findings Over the last 5 years, there has been substantial progress, initially in animal models and more recently in clinical studies, to establish methods and develop workflows within the MR environment that resemble those of conventional electrophysiology laboratories. Real-time MRI-guided systems have been used to perform electroanatomic mapping and ablation in patients with atrial flutter, and there is interest in developing the technology to tackle more complex arrhythmias including atrial fibrillation and ventricular tachycardia. Summary Mainstream adoption of real-time MRI-guided electrophysiology will require demonstration of clinical benefit and will be aided by increased availability of devices suitable for use in the MRI environment.
      PubDate: 2019-02-12
  • Machine Learning in the Evaluation of Myocardial Ischemia Through Nuclear
    • Abstract: Purpose of Review To summarize the advances achieved in the detection and characterization of myocardial ischemia and prediction of related outcomes through machine learning (ML)-based artificial intelligence (AI) workflows in both single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Recent Findings In the field of cardiology, the implementation of ML algorithms has recently gravitated around image processing for characterization, diagnostic, and prognostic purposes. Nuclear cardiology represents a particular niche for AI as it deals with complex images of semi-quantitative and quantitative nature acquired with SPECT and PET. Summary AI is revolutionizing clinical research. Since the recent convergence of powerful ML algorithms and increasing computational power, the study of very large datasets has demonstrated that clinical classification and prediction can be optimized by exploring very high-dimensional non-linear patterns. In the evaluation of myocardial ischemia, ML is optimizing the recognition of perfusion abnormalities beyond traditional measures and refining prediction of adverse cardiovascular events at the individual-patient level.
      PubDate: 2019-02-09
  • Myocardial Perfusion Imaging for the Evaluation of Ischemic Heart Disease
           in Women
    • Abstract: Purpose of the Review To review the value of myocardial blood flow and coronary flow reserve (CFR) measurements, as assessed by positron emission tomography (PET), in women with suspected ischemic heart disease. Recent Findings CFR is a noninvasive measure of coronary vasomotor function that integrates the hemodynamic effects of epicardial coronary stenosis, diffuse atherosclerosis, and microvascular dysfunction on myocardial tissue perfusion and has emerged as an imaging marker of cardiovascular risk, independently of the degree of obstructive coronary artery disease (CAD). Summary Normal coronary arteries or nonobstructive CAD is a common finding in women with ischemia. Thus, assessment of risk based on a coronary stenosis approach may fail in women. PET is able to quantify absolute myocardial blood flow and CFR which may help to elucidate other mechanisms involved such as microvascular dysfunction and diffuse epicardial CAD, responsible for the disease in women.
      PubDate: 2019-01-25
  • Stress Protocol and Myocardial Perfusion Imaging Accuracy
    • Abstract: Purpose of Review To evaluate the most recent evolutions in the field of single photon emission computed tomography (SPECT) nuclear cardiac imaging (NCI), particularly regarding the influence of stress protocol specifics on test accuracy. Recent Findings The substantial improvement in both software and hardware SPECT settings may allow a drastic redefinition of the acquisition parameters, with a radical reduction of scanning time. Moreover, recent evidence has identified novel (contra)-indications to the different cardiac stressors, defining the categories of patients in which a specific stressor is most appropriate. Summary Whilst exercise stress is favoured in the majority of patients submitted to SPECT NCI, in patients with atrial fibrillation or diabetes mellitus, a vasodilator stress may be preferred because of a significantly higher specificity. Moreover, the use of non-perfusion variables, such as post-stress diastolic left ventricular parameters or eccentricity index, is favoured to increase the accuracy of SPECT imaging. Finally, the quantification of myocardial blood flow through dynamic scans with cadmium-zinc-telluride cameras is gaining its way in clinical practice, possibly further increasing NCI accuracy in the most difficult patients.
      PubDate: 2019-01-16
  • Microvascular Dysfunction in Hypertrophic Cardiomyopathy
    • Abstract: Purpose of Review In hypertrophic cardiomyopathy (HCM), the presence of vessel abnormalities with microvascular dysfunction is a well-known feature. The aim of this review is to present the evidences that support this notion and to describe the physiopathologic and clinical consequences of microvascular dysfunction. Recent Findings After having demonstrated the presence and significance of microvascular dysfunction in HCM, the myocardial blood flow (MBF) measurement by positron emission tomography (PET) is ready to develop into a clinical tool for disease evaluation, in particular for patient prognostication. Alternative methods are becoming available, but they are not yet equally reliable. Summary By means of MBF measurement using quantitative PET, the importance of microvascular dysfunction in HCM has been clearly demonstrated, explaining the chest pain and the ischemic abnormalities frequently registered in this disease. The physiopathologic implications of microvascular dysfunction have been established, and an increasing number of reports indicate that the assessment of microvascular dysfunction is as well important for patient characterization and prognostication. Most recently, perfusion measurements using magnetic resonance imaging have been used, but their role is still under debate.
      PubDate: 2019-01-16
  • Correction to: Coronary CTA for Surveillance of Cardiac Allograft
    • Abstract: The article Coronary CTA for Surveillance of Cardiac Allograft Vasculopathy, written by Nishant R. Shah, Ron Blankstein, Todd Villines, Hafiz Imran, Alan R. Morrison and Michael K. Cheezum, was originally published electronically on the publisher’s internet portal.
      PubDate: 2018-11-08
  • Diastolic Assessment: Application of the New ASE Guidelines
    • Abstract: Purpose of Review The purpose of this review is to summarize the new guidelines from the American Society of Echocardiography (ASE) and the European Association of Cardiovascular Imaging (EACVI) for the diagnosis and grading of diastolic dysfunction (DD), with commentary on the rationale behind the use of the recommended individual parameters. Recent Findings Previous guidelines for assessment of diastolic function have been criticized for being too complex with modest diagnostic performance and inter-observer variability. Summary The new ASE/EACVI diastology guidelines aim to simplify the diagnosis and gradation of DD by using a limited set of echocardiographic variables. The robustness of these recommendations has been subsequently validated in several trials. Understanding the physiological principles that govern changes in echocardiographic parameters during normal and abnormal diastolic function is critical for the appropriate application of these recommendations.
      PubDate: 2018-10-31
  • IVUS- Versus OCT-Guided Coronary Stent Implantation: a Comparison of
           Intravascular Imaging for Stent Optimization
    • Abstract: Purpose of Review Intravascular imaging provides improved diagnostic accuracy and optimization of percutaneous coronary interventions (PCI) compared with angiography alone. We review the latest literature on the predominant intravascular imaging modalities, intravascular ultrasound (IVUS), and optical coherence tomography (OCT). Recent Findings A number of recently published clinical studies evaluating OCT and IVUS use have demonstrated improved procedural and clinical outcomes over angiography. Recent literature also reports on novel potential applications of these technologies. Summary Intravascular imaging is an important diagnostic tool that augments angiography. IVUS has been the primary adjunctive intravascular imaging modality in interventional cardiology over the past three decades, while OCT is a newer modality of growing clinical importance. Both modalities augment angiography alone while having their own specific advantages and disadvantages.
      PubDate: 2018-10-31
  • Diagnosis of Cardiac Amyloidosis: Clinical and Echocardiographic Features
    • Abstract: Purpose of Review This review is geared to address the various forms of amyloidosis which have cardiac involvement and discuss the echocardiographic findings that may be present in patients with cardiac amyloidosis. Recent Findings The use of echocardiography has revolutionized the diagnosis of cardiac amyloidosis. The diagnosis is often first suspected due to characteristic echocardiographic findings. Although no single finding is pathognomonic, there are a constellation of features that point to the diagnosis including increased left and right ventricular wall thickness, thickened cardiac valves and atrial walls, and a pericardial effusion. Alterations in diastolic function with evidence of elevated filling pressures are common. The use of myocardial strain imaging has allowed for earlier detection of cardiac amyloidosis and has revealed a distinctive pattern, sometimes suggesting the diagnosis when more classic findings are subtle or absent. Multiple echocardiographic findings have been found to be prognostic in cardiac amyloid. Using current techniques, functional measures such as myocardial strain and stroke volume index are more powerful predictors of outcome than myocardial thickness. While other imaging modalities are complementary including cardiac magnetic resonance imaging and nuclear medicine scintigraphy techniques using bone tracers, echocardiography remains a mainstay in the diagnosis and follow-up of patients with cardiac amyloidosis. Summary Echocardiography is a critical tool in the evaluation of the patient with heart failure, as well as those with unexplained chest pain and arrhythmias. Key findings on an echocardiogram can help alert the clinician to the presence of cardiac amyloidosis. The degree of cardiac dysfunction in a patient with systemic amyloidosis correlates with prognosis. Recognition of subtle echocardiographic findings may allow for earlier and more aggressive treatment to improve overall mortality in patients with cardiac amyloidosis.
      PubDate: 2018-10-23
  • Stress Echocardiography: the Role in Assessing Valvular Heart Diseases
    • Abstract: Purpose of Review Stress echocardiography (SE) has clinical utility beyond its conventional use for the evaluation of myocardial ischemia. More specifically, SE has been shown to have significant clinical value in patients with valvular heart disease (VHD), hypertrophic cardiomyopathy (HCM), and congenital heart disease (CHD). Echocardiography laboratories providing services to such patient should be familiar with the principals of SE beyond coronary artery disease to ensure its optimum application and performance. Recent Findings The increased demand for SE standardization specifically in patients with VHD instigated recent recommendations by relevant cardiology societies. Summary This manuscript reviews the key concepts in performance and interpretation of hemodynamic SE in patients with VHD and HCM, including patient selection, stress modality of choice, and integration of all diagnostic and prognostic information.
      PubDate: 2018-10-23
  • Intravascular Imaging for Chronic Total Occlusion Intervention
    • Abstract: Purpose of Review We sought to summarize the current evidence on use of intravascular imaging (with intravascular ultrasound [IVUS] or optical coherence tomography [OCT]) in chronic total occlusion (CTO) percutaneous coronary intervention (PCI). Recent Findings Utilization of intravascular imaging in CTO PCI is increasing over time, both to facilitate CTO crossing and for optimization of the final result. OCT is used less often than IVUS due to its lower depth of penetration and need for contrast injection. Summary Intravascular imaging has multiple uses in CTO PCI: (a) it can facilitate CTO crossing by resolving proximal cap ambiguity and facilitating and confirming true lumen wire re-entry in case of initial subintimal wire crossing in both the antegrade and retrograde direction (for example by selecting the appropriate balloon size during the reverse controlled antegrade and retrograde tracking (reverse CART) technique; (b) it can be used to optimize the PCI result by ensuring good stent expansion and stent strut apposition, which may in turn result in lower rates of subsequent in-stent restenosis and stent thrombosis; (c) can facilitate evaluation and treatment of complications.
      PubDate: 2018-10-17
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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