Subjects -> MEDICAL SCIENCES (Total: 8677 journals)
    - ALLERGOLOGY AND IMMUNOLOGY (219 journals)
    - ANAESTHESIOLOGY (120 journals)
    - CARDIOVASCULAR DISEASES (338 journals)
    - CHIROPRACTIC, HOMEOPATHY, OSTEOPATHY (21 journals)
    - COMMUNICABLE DISEASES, EPIDEMIOLOGY (235 journals)
    - DENTISTRY (294 journals)
    - DERMATOLOGY AND VENEREOLOGY (164 journals)
    - EMERGENCY AND INTENSIVE CRITICAL CARE (124 journals)
    - ENDOCRINOLOGY (151 journals)
    - FORENSIC SCIENCES (42 journals)
    - GASTROENTEROLOGY AND HEPATOLOGY (189 journals)
    - GERONTOLOGY AND GERIATRICS (138 journals)
    - HEMATOLOGY (157 journals)
    - HYPNOSIS (4 journals)
    - INTERNAL MEDICINE (177 journals)
    - LABORATORY AND EXPERIMENTAL MEDICINE (99 journals)
    - MEDICAL GENETICS (58 journals)
    - MEDICAL SCIENCES (2410 journals)
    - NURSES AND NURSING (367 journals)
    - OBSTETRICS AND GYNECOLOGY (207 journals)
    - ONCOLOGY (386 journals)
    - OPHTHALMOLOGY AND OPTOMETRY (141 journals)
    - ORTHOPEDICS AND TRAUMATOLOGY (170 journals)
    - OTORHINOLARYNGOLOGY (83 journals)
    - PATHOLOGY (100 journals)
    - PEDIATRICS (275 journals)
    - PHYSICAL MEDICINE AND REHABILITATION (158 journals)
    - PSYCHIATRY AND NEUROLOGY (833 journals)
    - RADIOLOGY AND NUCLEAR MEDICINE (192 journals)
    - RESPIRATORY DISEASES (104 journals)
    - RHEUMATOLOGY (79 journals)
    - SPORTS MEDICINE (81 journals)
    - SURGERY (406 journals)
    - UROLOGY, NEPHROLOGY AND ANDROLOGY (155 journals)

CARDIOVASCULAR DISEASES (338 journals)                  1 2 | Last

Showing 1 - 200 of 338 Journals sorted alphabetically
Acta Angiologica     Open Access   (Followers: 5)
Acta Cardiologica     Hybrid Journal   (Followers: 2)
Acute Cardiac Care     Hybrid Journal   (Followers: 8)
Adipositas - Ursachen, Folgeerkrankungen, Therapie     Hybrid Journal  
AJP Heart and Circulatory Physiology     Hybrid Journal   (Followers: 12)
Aktuelle Kardiologie     Hybrid Journal   (Followers: 1)
American Heart Journal     Hybrid Journal   (Followers: 60)
American Journal of Cardiology     Hybrid Journal   (Followers: 68)
American Journal of Cardiovascular Drugs     Hybrid Journal   (Followers: 18)
American Journal of Hypertension     Hybrid Journal   (Followers: 29)
Anales de Cirugia Vascular     Full-text available via subscription   (Followers: 1)
Anatolian Journal of Cardiology     Open Access   (Followers: 6)
Angiología     Full-text available via subscription  
Angiologia e Cirurgia Vascular     Open Access   (Followers: 1)
Angiology     Hybrid Journal   (Followers: 3)
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (Followers: 1)
Annals of Circulation     Open Access   (Followers: 2)
Annals of Noninvasive Electrocardiology     Hybrid Journal   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 12)
AORTA     Open Access  
Archives of Cardiovascular Diseases     Full-text available via subscription   (Followers: 6)
Archives of Cardiovascular Diseases Supplements     Full-text available via subscription   (Followers: 4)
Archives of Cardiovascular Imaging     Open Access   (Followers: 2)
Archivos de cardiología de México     Open Access   (Followers: 1)
Argentine Journal of Cardiology (English edition)     Open Access   (Followers: 2)
Arquivos Brasileiros de Cardiologia     Open Access   (Followers: 2)
Arrhythmia & Electrophysiology Review     Open Access   (Followers: 1)
Arteriosclerosis, Thrombosis and Vascular Biology     Full-text available via subscription   (Followers: 33)
Artery Research     Hybrid Journal   (Followers: 5)
ARYA Atherosclerosis     Open Access  
ASAIO Journal     Hybrid Journal   (Followers: 4)
ASEAN Heart Journal     Open Access   (Followers: 3)
Asian Cardiovascular and Thoracic Annals     Hybrid Journal   (Followers: 2)
Aswan Heart Centre Science & Practice Services     Open Access   (Followers: 1)
Atherosclerosis : X     Open Access  
Bangladesh Heart Journal     Open Access   (Followers: 3)
Basic Research in Cardiology     Hybrid Journal   (Followers: 9)
BMC Cardiovascular Disorders     Open Access   (Followers: 22)
Brain Circulation     Open Access   (Followers: 1)
British Journal of Cardiology     Full-text available via subscription   (Followers: 18)
Canadian Journal of Cardiology     Hybrid Journal   (Followers: 18)
Cardiac Cath Lab Director     Full-text available via subscription  
Cardiac Electrophysiology Review     Hybrid Journal   (Followers: 2)
Cardiac Failure Review     Open Access   (Followers: 2)
Cardiocore     Full-text available via subscription   (Followers: 1)
Cardiogenetics     Open Access   (Followers: 3)
Cardiology     Full-text available via subscription   (Followers: 20)
Cardiology and Angiology: An International Journal     Open Access   (Followers: 1)
Cardiology and Therapy     Open Access   (Followers: 11)
Cardiology Clinics     Full-text available via subscription   (Followers: 14)
Cardiology in Review     Hybrid Journal   (Followers: 9)
Cardiology in the Young     Hybrid Journal   (Followers: 35)
Cardiology Journal     Open Access   (Followers: 6)
Cardiology Plus     Open Access   (Followers: 1)
Cardiology Research     Open Access   (Followers: 15)
Cardiology Research and Practice     Open Access   (Followers: 11)
Cardiopulmonary Physical Therapy Journal     Hybrid Journal   (Followers: 9)
Cardiorenal Medicine     Full-text available via subscription   (Followers: 1)
Cardiothoracic Surgeon     Open Access   (Followers: 1)
CardioVasc     Full-text available via subscription   (Followers: 1)
Cardiovascular & Haematological Disorders - Drug Targets     Hybrid Journal   (Followers: 1)
Cardiovascular & Hematological Agents in Medicinal Chemistry     Hybrid Journal   (Followers: 2)
CardioVascular and Interventional Radiology     Hybrid Journal   (Followers: 15)
Cardiovascular and Thoracic Open     Open Access  
Cardiovascular Diabetology     Open Access   (Followers: 10)
Cardiovascular Drugs and Therapy     Hybrid Journal   (Followers: 14)
Cardiovascular Endocrinology & Metabolism     Hybrid Journal   (Followers: 1)
Cardiovascular Engineering     Hybrid Journal   (Followers: 1)
Cardiovascular Engineering and Technology     Hybrid Journal   (Followers: 1)
Cardiovascular Intervention and Therapeutics     Hybrid Journal   (Followers: 5)
Cardiovascular Journal     Open Access   (Followers: 6)
Cardiovascular Journal of Africa     Full-text available via subscription   (Followers: 5)
Cardiovascular Journal of South Africa     Full-text available via subscription   (Followers: 2)
Cardiovascular Medicine in General Practice     Full-text available via subscription   (Followers: 7)
Cardiovascular Pathology     Hybrid Journal   (Followers: 4)
Cardiovascular Regenerative Medicine     Open Access  
Cardiovascular Research     Hybrid Journal   (Followers: 16)
Cardiovascular Revascularization Medicine     Hybrid Journal   (Followers: 1)
Cardiovascular System     Open Access  
Cardiovascular Therapeutics     Open Access   (Followers: 1)
Cardiovascular Toxicology     Hybrid Journal   (Followers: 6)
Cardiovascular Ultrasound     Open Access   (Followers: 5)
Case Reports in Cardiology     Open Access   (Followers: 7)
Catheterization and Cardiovascular Interventions     Hybrid Journal   (Followers: 3)
Cerebrovascular Diseases     Full-text available via subscription   (Followers: 3)
Cerebrovascular Diseases Extra     Open Access  
Chest     Full-text available via subscription   (Followers: 104)
Choroby Serca i Naczyń     Open Access   (Followers: 1)
Circulation     Hybrid Journal   (Followers: 269)
Circulation : Cardiovascular Imaging     Hybrid Journal   (Followers: 15)
Circulation : Cardiovascular Interventions     Hybrid Journal   (Followers: 19)
Circulation : Cardiovascular Quality and Outcomes     Hybrid Journal   (Followers: 12)
Circulation : Genomic and Precision Medicine     Hybrid Journal   (Followers: 17)
Circulation : Heart Failure     Hybrid Journal   (Followers: 28)
Circulation Research     Hybrid Journal   (Followers: 36)
Cirugía Cardiovascular     Open Access  
Clínica e Investigación en Arteriosclerosis     Full-text available via subscription  
Clínica e Investigación en arteriosclerosis (English Edition)     Hybrid Journal  
Clinical and Experimental Hypertension     Hybrid Journal   (Followers: 3)
Clinical Cardiology     Hybrid Journal   (Followers: 10)
Clinical Hypertension     Open Access   (Followers: 5)
Clinical Medicine Insights : Cardiology     Open Access   (Followers: 6)
Clinical Research in Cardiology     Hybrid Journal   (Followers: 5)
Clinical Research in Cardiology Supplements     Hybrid Journal  
Clinical Trials and Regulatory Science in Cardiology     Open Access   (Followers: 4)
Congenital Heart Disease     Hybrid Journal   (Followers: 6)
Congestive Heart Failure     Hybrid Journal   (Followers: 4)
Cor et Vasa     Full-text available via subscription   (Followers: 1)
Coronary Artery Disease     Hybrid Journal   (Followers: 3)
CorSalud     Open Access  
Critical Pathways in Cardiology     Hybrid Journal   (Followers: 5)
Current Cardiology Reports     Hybrid Journal   (Followers: 6)
Current Cardiology Reviews     Hybrid Journal   (Followers: 3)
Current Cardiovascular Imaging Reports     Hybrid Journal   (Followers: 1)
Current Cardiovascular Risk Reports     Hybrid Journal  
Current Heart Failure Reports     Hybrid Journal   (Followers: 5)
Current Hypertension Reports     Hybrid Journal   (Followers: 6)
Current Hypertension Reviews     Hybrid Journal   (Followers: 6)
Current Opinion in Cardiology     Hybrid Journal   (Followers: 13)
Current Problems in Cardiology     Hybrid Journal   (Followers: 3)
Current Research : Cardiology     Full-text available via subscription   (Followers: 1)
Current Treatment Options in Cardiovascular Medicine     Hybrid Journal   (Followers: 1)
Current Vascular Pharmacology     Hybrid Journal   (Followers: 5)
CVIR Endovascular     Open Access   (Followers: 1)
Der Kardiologe     Hybrid Journal   (Followers: 1)
Echo Research and Practice     Open Access   (Followers: 2)
Echocardiography     Hybrid Journal   (Followers: 4)
Egyptian Heart Journal     Open Access   (Followers: 2)
Egyptian Journal of Cardiothoracic Anesthesia     Open Access  
ESC Heart Failure     Open Access   (Followers: 4)
European Cardiology Review     Open Access   (Followers: 1)
European Heart Journal     Hybrid Journal   (Followers: 68)
European Heart Journal - Cardiovascular Imaging     Hybrid Journal   (Followers: 10)
European Heart Journal - Cardiovascular Pharmacotherapy     Full-text available via subscription   (Followers: 2)
European Heart Journal - Quality of Care and Clinical Outcomes     Hybrid Journal  
European Heart Journal : Acute Cardiovascular Care     Hybrid Journal   (Followers: 1)
European Heart Journal : Case Reports     Open Access   (Followers: 1)
European Heart Journal Supplements     Hybrid Journal   (Followers: 7)
European Journal of Cardio-Thoracic Surgery     Hybrid Journal   (Followers: 9)
European Journal of Cardio-Thoracic Surgery Supplements     Full-text available via subscription   (Followers: 2)
European Journal of Cardiovascular Nursing     Hybrid Journal   (Followers: 5)
European Journal of Heart Failure     Hybrid Journal   (Followers: 13)
European Journal of Preventive Cardiology.     Hybrid Journal   (Followers: 6)
European Stroke Organisation     Hybrid Journal   (Followers: 3)
Experimental & Translational Stroke Medicine     Open Access   (Followers: 9)
Expert Review of Cardiovascular Therapy     Full-text available via subscription   (Followers: 3)
Folia Cardiologica     Open Access  
Forum Zaburzeń Metabolicznych     Hybrid Journal  
Frontiers in Cardiovascular Medicine     Open Access   (Followers: 1)
Future Cardiology     Hybrid Journal   (Followers: 5)
General Thoracic and Cardiovascular Surgery     Hybrid Journal   (Followers: 3)
Global Cardiology Science and Practice     Open Access   (Followers: 5)
Global Heart     Hybrid Journal   (Followers: 3)
Heart     Hybrid Journal   (Followers: 49)
Heart and Mind     Open Access  
Heart and Vessels     Hybrid Journal  
Heart Failure Clinics     Full-text available via subscription   (Followers: 2)
Heart Failure Reviews     Hybrid Journal   (Followers: 3)
Heart India     Open Access   (Followers: 2)
Heart International     Full-text available via subscription  
Heart Rhythm     Hybrid Journal   (Followers: 11)
Heart Views     Open Access   (Followers: 2)
HeartRhythm Case Reports     Open Access  
Hellenic Journal of Cardiology     Open Access   (Followers: 1)
Herz     Hybrid Journal   (Followers: 2)
High Blood Pressure & Cardiovascular Prevention     Full-text available via subscription   (Followers: 2)
Hypertension     Full-text available via subscription   (Followers: 24)
Hypertension     Open Access   (Followers: 2)
Hypertension in Pregnancy     Hybrid Journal   (Followers: 9)
Hypertension Research     Hybrid Journal   (Followers: 4)
Ibrahim Cardiac Medical Journal     Open Access  
IJC Heart & Vessels     Open Access   (Followers: 1)
IJC Heart & Vasculature     Open Access   (Followers: 1)
IJC Metabolic & Endocrine     Open Access   (Followers: 1)
Indian Heart Journal     Open Access   (Followers: 5)
Indian Journal of Cardiovascular Disease in Women WINCARS     Open Access  
Indian Journal of Thoracic and Cardiovascular Surgery     Hybrid Journal  
Indian Pacing and Electrophysiology Journal     Open Access   (Followers: 1)
Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery     Hybrid Journal   (Followers: 1)
Insuficiencia Cardíaca     Open Access  
Interactive CardioVascular and Thoracic Surgery     Hybrid Journal   (Followers: 6)
International Cardiovascular Forum Journal     Open Access  
International Journal of Angiology     Hybrid Journal   (Followers: 2)
International Journal of Cardiology     Hybrid Journal   (Followers: 17)
International Journal of Cardiology Hypertension     Open Access   (Followers: 1)
International Journal of Cardiovascular and Cerebrovascular Disease     Open Access   (Followers: 3)
International Journal of Cardiovascular Imaging     Hybrid Journal   (Followers: 2)
International Journal of Cardiovascular Research     Hybrid Journal   (Followers: 6)
International Journal of Heart Rhythm     Open Access  
International Journal of Hypertension     Open Access   (Followers: 8)
International Journal of Hyperthermia     Open Access  
International Journal of Stroke     Hybrid Journal   (Followers: 33)
International Journal of the Cardiovascular Academy     Open Access  
Interventional Cardiology Clinics     Full-text available via subscription   (Followers: 2)
Interventional Cardiology Review     Open Access  
JACC : Basic to Translational Science     Open Access   (Followers: 6)
JACC : Cardiovascular Imaging     Hybrid Journal   (Followers: 19)
JACC : Cardiovascular Interventions     Hybrid Journal   (Followers: 21)
JACC : Heart Failure     Full-text available via subscription   (Followers: 16)
JAMA Cardiology     Hybrid Journal   (Followers: 31)

        1 2 | Last

Similar Journals
Journal Cover
European Heart Journal
Journal Prestige (SJR): 9.315
Citation Impact (citeScore): 9
Number of Followers: 68  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0195-668X - ISSN (Online) 1522-9645
Published by Oxford University Press Homepage  [412 journals]
  • Nutrition, obesity, diabetes, and cardiovascular outcomes: a deadly
           association
    • Authors: Lüscher T.
      Pages: 2603 - 2607
      PubDate: Thu, 23 Jul 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa622
      Issue No: Vol. 41, No. 28 (2020)
       
  • Fritz Albert Lipmann
    • Authors: Nicholls M.
      Pages: 2608 - 2609
      Abstract: Mark Nicholls focuses on the work of German–American biochemist Fritz Lipmann who was awarded the 1953 Nobel Prize in Physiology or Medicine for his discovery of coenzyme A (CoA).
      PubDate: Mon, 24 Feb 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa152
      Issue No: Vol. 41, No. 28 (2020)
       
  • The European Association of Preventive Cardiology
    • Authors: Dendale P, Prof. dr; Janssen A.
      Pages: 2610 - 2611
      Abstract: The Association that provides lifelong cardiovascular disease prevention
      PubDate: Thu, 23 Jul 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa203
      Issue No: Vol. 41, No. 28 (2020)
       
  • Is vaping better than smoking cigarettes'
    • Authors: Münzel T; Kuntic M, Steven S, et al.
      Pages: 2612 - 2614
      Abstract: Thomas Münzel and co-authors report from Mainz on the pros and cons of e-cigarette smoking
      PubDate: Thu, 23 Jul 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa267
      Issue No: Vol. 41, No. 28 (2020)
       
  • The ESC Working Group on Cellular Biology of the Heart
    • Authors: Madonna R.
      Pages: 2614 - 2616
      PubDate: Thu, 23 Jul 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa312
      Issue No: Vol. 41, No. 28 (2020)
       
  • Beth Levine In Memoriam
    • Authors: Packer M.
      Pages: 2617 - 2617
      Abstract: A brilliant physician-scientist having spearheaded major advances in the molecular biology of autophagy, a Howard Hughes investigator and member of the US National Academy of Sciences has departed
      PubDate: Thu, 23 Jul 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa563
      Issue No: Vol. 41, No. 28 (2020)
       
  • Genetic variability in the absorption of dietary sterols affects the risk
           of coronary artery disease
    • Authors: Helgadottir A; Thorleifsson G, Alexandersson K, et al.
      Pages: 2618 - 2628
      Abstract: AbstractAimsTo explore whether variability in dietary cholesterol and phytosterol absorption impacts the risk of coronary artery disease (CAD) using as instruments sequence variants in the ABCG5/8 genes, key regulators of intestinal absorption of dietary sterols.Methods and resultsWe examined the effects of ABCG5/8 variants on non-high-density lipoprotein (non-HDL) cholesterol (N up to 610 532) and phytosterol levels (N = 3039) and the risk of CAD in Iceland, Denmark, and the UK Biobank (105 490 cases and 844 025 controls). We used genetic scores for non-HDL cholesterol to determine whether ABCG5/8 variants confer greater risk of CAD than predicted by their effect on non-HDL cholesterol. We identified nine rare ABCG5/8 coding variants with substantial impact on non-HDL cholesterol. Carriers have elevated phytosterol levels and are at increased risk of CAD. Consistent with impact on ABCG5/8 transporter function in hepatocytes, eight rare ABCG5/8 variants associate with gallstones. A genetic score of ABCG5/8 variants predicting 1 mmol/L increase in non-HDL cholesterol associates with two-fold increase in CAD risk [odds ratio (OR) = 2.01, 95% confidence interval (CI) 1.75–2.31, P = 9.8 × 10−23] compared with a 54% increase in CAD risk (OR = 1.54, 95% CI 1.49–1.59, P = 1.1 × 10−154) associated with a score of other non-HDL cholesterol variants predicting the same increase in non-HDL cholesterol (P for difference in effects = 2.4 × 10−4).ConclusionsGenetic variation in cholesterol absorption affects levels of circulating non-HDL cholesterol and risk of CAD. Our results indicate that both dietary cholesterol and phytosterols contribute directly to atherogenesis.
      PubDate: Thu, 23 Jul 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa531
      Issue No: Vol. 41, No. 28 (2020)
       
  • Choriocarcinoma metastasis in the left atrium
    • Authors: Li Y; Yan L, Shui S, et al.
      Pages: 2628 - 2628
      Abstract: A 36-year-old woman was transferred to our hospital with dizziness and headache for 10 days and had left-side hemiparesis for 1 day. Head computed tomography suggested multiple intracerebral haemorrhages. Digital subtraction angiography showed that the right internal carotid artery was occluded (Panel A, Video S1). During angiography, a mass in the right lung was observed by accident (Panel B). Chest-enhanced computed tomography revealed a solid 35-mm × 32-mm mass in the right lung with intermediate bronchus stenosis (Panel C). Additionally, the left atrium and pulmonary vein showed tumour invasion (Panels C and D). The patient had no respiratory system symptoms. However, she complained of a 6-month history of irregular vaginal bleeding after full-term delivery of a baby. Blood tests revealed a β-human chorionic gonadotropin (HCG) concentration of 3.5 × 105 mIU/mL but vaginal ultrasound suggested no abnormalities.
      PubDate: Tue, 24 Mar 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa163
      Issue No: Vol. 41, No. 28 (2020)
       
  • It’s time to personalize and optimize lipid-lowering therapy
    • Authors: Weingärtner O; Patel S, Lütjohann D.
      Pages: 2629 - 2631
      Abstract: Abstract
      PubDate: Thu, 23 Jul 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa445
      Issue No: Vol. 41, No. 28 (2020)
       
  • The associations of major foods and fibre with risks of ischaemic and
           haemorrhagic stroke: a prospective study of 418 329 participants in the
           EPIC cohort across nine European countries
    • Authors: Tong T; Appleby P, Key T, et al.
      Pages: 2632 - 2640
      Abstract: AbstractAimTo investigate the associations between major foods and dietary fibre with subtypes of stroke in a large prospective cohort.Methods and resultsWe analysed data on 418 329 men and women from nine European countries, with an average of 12.7 years of follow-up. Diet was assessed using validated country-specific questionnaires which asked about habitual intake over the past year, calibrated using 24-h recalls. Multivariable-adjusted Cox regressions were used to estimate hazard ratios (HRs) for ischaemic and haemorrhagic stroke associated with consumption of red and processed meat, poultry, fish, dairy foods, eggs, cereals, fruit and vegetables, legumes, nuts and seeds, and dietary fibre. For ischaemic stroke (4281 cases), lower risks were observed with higher consumption of fruit and vegetables combined (HR; 95% CI per 200 g/day higher intake, 0.87; 0.82–0.93, P-trend < 0.001), dietary fibre (per 10 g/day, 0.77; 0.69–0.86, P-trend < 0.001), milk (per 200 g/day, 0.95; 0.91–0.99, P-trend = 0.02), yogurt (per 100 g/day, 0.91; 0.85–0.97, P-trend = 0.004), and cheese (per 30 g/day, 0.88; 0.81–0.97, P-trend = 0.008), while higher risk was observed with higher red meat consumption which attenuated when adjusted for the other statistically significant foods (per 50 g/day, 1.07; 0.96–1.20, P-trend = 0.20). For haemorrhagic stroke (1430 cases), higher risk was associated with higher egg consumption (per 20 g/day, 1.25; 1.09–1.43, P-trend = 0.002).ConclusionRisk of ischaemic stroke was inversely associated with consumption of fruit and vegetables, dietary fibre, and dairy foods, while risk of haemorrhagic stroke was positively associated with egg consumption. The apparent differences in the associations highlight the importance of examining ischaemic and haemorrhagic stroke subtypes separately.
      PubDate: Mon, 24 Feb 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa007
      Issue No: Vol. 41, No. 28 (2020)
       
  • Diet and health: the need for new and reliable approaches
    • Authors: Mente* A; Dehghan M, Yusuf S.
      Pages: 2641 - 2644
      Abstract: This editorial refers to ‘The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries’††, by T.Y.N. Tong et al., on page 2632.
      PubDate: Wed, 29 Apr 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa317
      Issue No: Vol. 41, No. 28 (2020)
       
  • The Mediterranean diet, plasma metabolome, and cardiovascular disease risk
    • Authors: Li J; Guasch-Ferré M, Chung W, et al.
      Pages: 2645 - 2656
      Abstract: AbstractAimsTo investigate whether metabolic signature composed of multiple plasma metabolites can be used to characterize adherence and metabolic response to the Mediterranean diet and whether such a metabolic signature is associated with cardiovascular disease (CVD) risk.Methods and resultsOur primary study cohort included 1859 participants from the Spanish PREDIMED trial, and validation cohorts included 6868 participants from the US Nurses’ Health Studies I and II, and Health Professionals Follow-up Study (NHS/HPFS). Adherence to the Mediterranean diet was assessed using a validated Mediterranean Diet Adherence Screener (MEDAS), and plasma metabolome was profiled by liquid chromatography-tandem mass spectrometry. We observed substantial metabolomic variation with respect to Mediterranean diet adherence, with nearly one-third of the assayed metabolites significantly associated with MEDAS (false discovery rate < 0.05). Using elastic net regularized regressions, we identified a metabolic signature, comprised of 67 metabolites, robustly correlated with Mediterranean diet adherence in both PREDIMED and NHS/HPFS (r = 0.28–0.37 between the signature and MEDAS; P = 3 × 10−35 to 4 × 10−118). In multivariable Cox regressions, the metabolic signature showed a significant inverse association with CVD incidence after adjusting for known risk factors (PREDIMED: hazard ratio [HR] per standard deviation increment in the signature = 0.71, P < 0.001; NHS/HPFS: HR = 0.85, P = 0.001), and the association persisted after further adjustment for MEDAS scores (PREDIMED: HR = 0.73, P = 0.004; NHS/HPFS: HR = 0.85, P = 0.004). Further genome-wide association analysis revealed that the metabolic signature was significantly associated with genetic loci involved in fatty acids and amino acids metabolism. Mendelian randomization analyses showed that the genetically inferred metabolic signature was significantly associated with risk of coronary heart disease (CHD) and stroke (odds ratios per SD increment in the genetically inferred metabolic signature = 0.92 for CHD and 0.91 for stroke; P < 0.001).ConclusionsWe identified a metabolic signature that robustly reflects adherence and metabolic response to a Mediterranean diet, and predicts future CVD risk independent of traditional risk factors, in Spanish and US cohorts.
      PubDate: Thu, 14 May 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa209
      Issue No: Vol. 41, No. 28 (2020)
       
  • The metabolic signature: an emerging paradigm in cardiovascular
           nutritional health research'
    • Authors: Sharma S; Parry-Williams G, Gati S.
      Pages: 2657 - 2659
      Abstract: This editorial refers to ‘The Mediterranean diet, plasma metabolome, and cardiovascular disease risk’††, by J. Li et al., on page 2645.
      PubDate: Fri, 01 May 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa260
      Issue No: Vol. 41, No. 28 (2020)
       
  • Effect of bariatric surgery on long-term cardiovascular outcomes: a
           nationwide nested cohort study
    • Authors: Moussa O; Ardissino M, Heaton T, et al.
      Pages: 2660 - 2667
      Abstract: AbstractAims This study aims to evaluate the long-term effect of bariatric surgery on cardiovascular outcomes of patients with obesity.Methods and results A nested cohort study was carried out within the Clinical Practice Research Datalink. The study cohort included the 3701 patients on the database who had undergone bariatric surgery and 3701 age, gender, and body mass index-matched controls. The primary endpoint was the composite of fatal or non-fatal myocardial infarction and fatal or non-fatal ischaemic stroke. Secondary endpoints included fatal or non-fatal myocardial infarction alone, fatal or non-fatal ischaemic stroke alone, incident heart failure, and mortality. The median follow-up achieved was 11.2 years. Patients who had undergone bariatric surgery had a significantly lower occurrence of major adverse cardiovascular events [hazard ratio (HR) 0.410, 95% confidence interval (CI) 0.274–0.615; P < 0.001]. This was mainly driven by a reduction in myocardial infarction (HR 0.412, 95% CI 0.280–0.606; P < 0.001) and not in acute ischaemic stroke (HR 0.536, 95% CI 0.164–1.748; P = 0.301). A reduction was also observed in new diagnoses of heart failure (HR 0.403, 95% CI 0.181–0.897; P = 0.026) and mortality (HR 0.254, 95% CI 0.183–0.353; P < 0.001).Conclusion The results of this large, nationwide cohort study support the association of bariatric surgery with lower long-term risk of major cardiovascular events and incident heart failure in patients with obesity.
      PubDate: Thu, 19 Mar 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa069
      Issue No: Vol. 41, No. 28 (2020)
       
  • Obesity and weight loss are inversely related to mortality and
           cardiovascular outcome in prediabetes and type 2 diabetes: data from the
           ORIGIN trial
    • Authors: Doehner W; Gerstein H, Ried J, et al.
      Pages: 2668 - 2677
      Abstract: AbstractAimsThe association of body weight and weight change with mortality and cardiovascular (CV) outcome in patients with diabetes mellitus (DM) is not clearly established. We assessed the relationship between weight, weight change, and outcomes in patients with established CV risk factors and type 2 DM or pre-diabetes.Methods and resultsA total of 12 521 participants from the ORIGIN trial were grouped in BMI categories of low body weight [body mass index (BMI) < 22 kg/m2] normal (22–24.9), overweight (25–29.9), obesity Grades 1–3 (30–34.9, 35–39.9, ≥40 kg/m2, respectively). Outcome variables included total and CV mortality and composite outcomes of CV death, non-fatal stroke, or myocardial infarction plus revascularization or heart failure hospitalization. Follow-up was 6.2 years (interquartile range 5.8–6.7 years). After multivariable adjustment, lowest risks were seen in patients with overweight and mild obesity for total mortality [overweight: hazard ratio (HR) 0.80 (95% confidence interval (CI) 0.69–0.91); obesity Grade 1: HR 0.82 (0.71–0.95), both P < 0.01)] and CV mortality [overweight: HR 0.79 (0.66–0.94); obesity Grade 1: 0.79 (0.65–0.95), all compared to patients with normal BMI, P < 0.05]. Obesity of any severity was not associated with higher mortality. Low body weight was related to higher mortality [HR 1.28 (1.02–1.61); CV mortality: HR 1.34 (1.01–1.79), P < 0.05]. A continued 2-year weight loss was associated with higher risk of mortality [HR 1.32 (1.18–1.46), P < 0.0001] and CV mortality [HR 1.18 (1.02–1.35), compared to patients without weight loss, P < 0.05]. In turn, weight gain was not related to any adverse outcome.ConclusionObesity in patients with DM or pre-diabetes and CV risk profile was not associated with higher mortality or adverse CV outcome. The lowest mortality risk was seen in patients with overweight and moderate obesity (BMI 25–35 kg/m2). Weight loss was an independent risk factor for higher mortality compared to no weight loss.
      PubDate: Wed, 13 May 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa293
      Issue No: Vol. 41, No. 28 (2020)
       
  • The obesity paradox in secondary prevention: a weighty intervention or a
           wait for more evidence'
    • Authors: Sattar N; Welsh P.
      Pages: 2678 - 2680
      Abstract: This editorial refers to ‘Obesity and weight loss are inversely related to mortality and cardiovascular outcome in prediabetes and type 2 diabetes: data from the ORIGIN trial’††, by W. Doehner et al., on page 2668.
      PubDate: Wed, 27 May 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa398
      Issue No: Vol. 41, No. 28 (2020)
       
  • Isolated atrial amyloidosis
    • Authors: Richter S; Jahnke C, Klingel K, et al.
      Pages: 2695 - 2695
      Abstract: A male octogenarian with a history of atrial fibrillation and diastolic heart failure presented with symptomatic sinus node dysfunction. Cardiac magnetic resonance imaging detected an extensive, storage disease-like signal pattern restricted to the atria only (Panels A and B: cine and dark-blood late gadolinium enhancement imaging) while ventricular myocardium, dimensions, and systolic function were normal (see Supplementary material online, Video S1Supplementary material online, Video S1). Endomyocardial biopsy of the interatrial septum and immunohistology confirmed the diagnosis of atrial amyloidosis (Panel C Congo red staining with green birefringence in polarized light; (Panel D) anti-atrial natriuretic peptide antibody staining). Electroanatomical right atrial voltage mapping (Panel E) revealed ubiquitous low-voltage (<0.5 mV) areas but a preserved high-amplitude signal of the bundle of His (dot cloud) which allowed for optimal pacemaker placement (turquoise dot, final lead position; HBE, His bundle electrogram; H, intrinsic potential; S-HBP stimulated potential).
      PubDate: Tue, 05 May 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa370
      Issue No: Vol. 41, No. 28 (2020)
       
  • A rare case of cardiac alveolar echinococcosis
    • Authors: Zhang X; Wei X, Ran L, et al.
      Pages: 2698 - 2698
      Abstract: A 31-year-old woman presented with cough, haemoptysis, palpitations (heart rate 102 b.p.m.), and fever (temperature 39°C). Magnetic resonance imaging (MRI) indicated multiple scattered nodules in the brain parenchyma (Panel A). Echocardiography showed a solid echoic mass (25 × 50 mm), which had unclear boundaries with the right atrial wall and pericardium (Panels B and C), extending from the inferior vena cava (IVC) to the right atrium (RA). Contrast-enhanced MRI showed soft tissue shadows in the IVC near the RA opening and the RA, and an enlarged spleen (Panel D). Serum immunological tests suggested the presence of Echinococcus antibodies. Considering the possibility of hydatid disease, the patient was administered albendazole for 1 month, and no significant change was observed on chest computed tomography or cardiac ultrasound. Therefore, cardiac surgery was performed. A grey-white hard mass (∼50 × 25 mm) was detected in the RA and IVC intraoperatively. The mass involved the right atrial wall, pericardium, and right phrenic nerve. The mass and a part of the right lower lung, pericardium, and diaphragm were removed. The post-operative pathological report showed hydatid disease (‘bubbly echinococcus’) with chronic inflammation and a granulomatous reaction (Panels E and H). One-year post-operatively, the patient was well and the lesion in the RA and IVC had disappeared (Panel F). The cerebral lesions had also significantly decreased (Panel G).
      PubDate: Thu, 23 Jul 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa511
      Issue No: Vol. 41, No. 28 (2020)
       
  • Sudden cardiac death in young patients with diabetes: a call to study
           additional causes beyond ischaemic heart disease
    • Authors: Tan H; van Dongen L, Zimmerman D.
      Pages: 2707 - 2709
      Abstract: Abstract
      PubDate: Fri, 07 Feb 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa011
      Issue No: Vol. 41, No. 28 (2020)
       
  • Clinical and conceptual approaches to interpreting the findings of
           systematic review and meta-analysis of mortality after drug-eluting stents
           
    • Authors: Jayaraj R; Kumaraswamy C, Shaw P.
      Pages: 2710 - 2711
      Abstract: This commentary refers to ‘Mortality after drug-eluting stents vs. coronary artery bypass grafting for left main coronary artery disease: a meta-analysis of randomized controlled trials’ by Y. Ahmad et al., doi:10.1093/eurheartj/ehaa135.
      PubDate: Fri, 26 Jun 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa387
      Issue No: Vol. 41, No. 28 (2020)
       
  • Bias, heterogeneity, and uncertainty in meta-analysis
    • Authors: Howard J; Arnold A, Ahmad Y.
      Pages: 2712 - 2712
      Abstract: This commentary refers to ‘Clinical and conceptual approaches to interpreting the findings of systematic review and meta-analysis of mortality after drug-eluting stents vs. coronary artery bypass grafting for left main coronary artery disease’ by R. Jayaraj et al., 2020;41:2710–2711.
      PubDate: Fri, 26 Jun 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa394
      Issue No: Vol. 41, No. 28 (2020)
       
  • Assessing causality in associations of lipid levels with aortic valve
           stenosis
    • Authors: Jiang Q; Chen M.
      Pages: 2713 - 2713
      Abstract: This commentary refers to ‘Plasma lipids and risk of aortic valve stenosis: a Mendelian randomization study’ by M. Nazarzadeh et al., doi: 10.1093/eurheartj/ehaa070.
      PubDate: Tue, 30 Jun 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa371
      Issue No: Vol. 41, No. 28 (2020)
       
  • Mendelian randomization of plasma lipids and aortic valve stenosis: the
           importance of outlier variants and population stratification
    • Authors: Nazarzadeh M; Rahimi K.
      Pages: 2714 - 2715
      Abstract: This commentary refers to ‘Plasma lipids and risk of aortic valve stenosis: a Mendelian randomization study’, by M. Nazarzadeh et al., doi:10.1093/eurheartj/ehaa070.
      PubDate: Mon, 06 Jul 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa476
      Issue No: Vol. 41, No. 28 (2020)
       
  • Myocardial involvement in Kugelberg–Welander disease
    • Authors: Sokolska J; Weber L, Niederseer D, et al.
      Pages: 2716 - 2716
      Abstract: A 55-year-old man with spinal muscular atrophy (SMA) Type 3b suffered from palpitations since the last few months, without concomitant dyspnoea or chest pain. Electrocardiogram (ECG) showed sinus rhythm (90 b.p.m.) and left axis deviation (Panel A). A long-term ECG documented sinus tachycardia, without any arrhythmia and conduction disturbances. Blood tests indicated elevated levels of serum creatinine kinase [268 U/L; normal (N) <190 U/L] and myoglobin (155 µg/L; N: 28–72 µg/L), and normal levels of N-terminal pro-B-type natriuretic peptide (121 ng/L; N < 121 ng/L) and high-sensitive troponin T (11 ng/L; N < 14 ng/L). Echocardiography revealed dilated, non-hypertrophic left ventricle (LV) with severely reduced ejection fraction (EF biplane = 32%) and akinesia of the basal and mid-lateral, mid-inferior, and inferio-apical segments. Heart failure therapy was established.
      PubDate: Sat, 27 Jun 2020 00:00:00 GMT
      DOI: 10.1093/eurheartj/ehaa522
      Issue No: Vol. 41, No. 28 (2020)
       
 
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