Subjects -> MEDICAL SCIENCES (Total: 8677 journals)
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PSYCHIATRY AND NEUROLOGY (833 journals)                  1 2 3 4 5 | Last

Showing 1 - 200 of 833 Journals sorted alphabetically
Academic Psychiatry     Full-text available via subscription   (Followers: 32)
Academic Psychiatry and Psychology Journal : APPJ     Open Access   (Followers: 13)
ACS Chemical Neuroscience     Hybrid Journal   (Followers: 24)
Acta Neurochirurgica     Hybrid Journal   (Followers: 7)
Acta Neurologica Belgica     Hybrid Journal   (Followers: 3)
Acta Neurológica Colombiana     Open Access   (Followers: 2)
Acta Neurologica Scandinavica     Hybrid Journal   (Followers: 6)
Acta Neuropathologica     Hybrid Journal   (Followers: 6)
Acta Neuropathologica Communications     Open Access   (Followers: 1)
Acta Neuropsychiatrica     Hybrid Journal   (Followers: 6)
Acta Psychiatrica Scandinavica     Hybrid Journal   (Followers: 44)
Actas Españolas de Psiquiatría     Free   (Followers: 2)
Activitas Nervosa Superior     Hybrid Journal  
ADHD Attention Deficit and Hyperactivity Disorders     Hybrid Journal   (Followers: 28)
ADHD Report The     Full-text available via subscription   (Followers: 12)
Administration and Policy in Mental Health and Mental Health Services Research     Partially Free   (Followers: 20)
Adolescent Psychiatry     Hybrid Journal   (Followers: 12)
Adolescent Research Review     Hybrid Journal   (Followers: 3)
Advances in Alzheimer's Disease     Open Access   (Followers: 16)
Advances in Clinical Neuroscience and Rehabilitation     Free   (Followers: 31)
Advances in Eating Disorders : Theory, Research and Practice     Hybrid Journal   (Followers: 18)
Advances in Mental Health     Hybrid Journal   (Followers: 91)
Advances in Parkinson's Disease     Open Access   (Followers: 1)
Advances in School Mental Health Promotion     Partially Free   (Followers: 12)
African Journal of Neurological Sciences     Open Access  
African Journal of Psychiatry     Full-text available via subscription   (Followers: 3)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 487)
Aggressive Behavior     Hybrid Journal   (Followers: 22)
Aging & Mental Health     Hybrid Journal   (Followers: 37)
Aging, Neuropsychology, and Cognition     Hybrid Journal   (Followers: 50)
AJOB Neuroscience     Hybrid Journal   (Followers: 5)
Aktuelle Neurologie     Hybrid Journal   (Followers: 9)
Alzheimer Disease & Associated Disorders     Hybrid Journal   (Followers: 20)
Alzheimer's & Dementia     Hybrid Journal   (Followers: 60)
Alzheimer's Research & Therapy     Open Access   (Followers: 4)
American Journal of Alzheimer's Disease and Other Dementias     Hybrid Journal   (Followers: 19)
American Journal of Clinical Hypnosis     Hybrid Journal   (Followers: 6)
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics     Hybrid Journal   (Followers: 4)
American Journal of Neuroprotection and Neuroregeneration     Full-text available via subscription   (Followers: 2)
American Journal of Psychiatric Rehabilitation     Hybrid Journal   (Followers: 13)
American Journal of Psychiatry     Full-text available via subscription   (Followers: 242)
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration     Hybrid Journal   (Followers: 2)
Analitika : Jurnal Magister Psikologi Uma     Open Access  
Annales Médico-psychologiques, revue psychiatrique     Full-text available via subscription   (Followers: 5)
Annals of Behavioral Medicine     Hybrid Journal   (Followers: 15)
Annals of Child Neurology     Open Access   (Followers: 1)
Annals of Clinical and Translational Neurology     Open Access   (Followers: 1)
Annals of Clinical Psychiatry : The official Journal of the American Academy of Clinical Psychiatrists     Hybrid Journal   (Followers: 28)
Annals of General Psychiatry     Open Access   (Followers: 28)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3)
Annals of Indian Psychiatry     Open Access  
Annals of Neurology     Hybrid Journal   (Followers: 61)
Annals of Neurosciences     Open Access   (Followers: 4)
Annals of Psychiatry and Treatment     Open Access   (Followers: 2)
Annual Review of Neuroscience     Full-text available via subscription   (Followers: 57)
Anxiety, Stress & Coping: An International Journal     Hybrid Journal   (Followers: 27)
Aphasiology     Hybrid Journal   (Followers: 55)
Applied Neuropsychology : Adult     Hybrid Journal   (Followers: 45)
Applied Neuropsychology : Child     Hybrid Journal   (Followers: 28)
Archives of Clinical Neuropsychology     Hybrid Journal   (Followers: 32)
Archives of Neuroscience     Open Access   (Followers: 6)
Archives of Psychiatric Nursing     Hybrid Journal   (Followers: 29)
Archives of Suicide Research     Hybrid Journal   (Followers: 9)
Archives of Women's Mental Health     Hybrid Journal   (Followers: 18)
Archivos de Neurociencias     Open Access   (Followers: 3)
Arquivos Brasileiros de Neurocirurgia : Brazilian Neurosurgery     Open Access  
Arquivos de Neuro-Psiquiatria     Open Access  
Art Therapy Online     Open Access   (Followers: 4)
Asia Pacific Journal of Counselling and Psychotherapy     Hybrid Journal   (Followers: 11)
Asian Journal of Psychiatry     Hybrid Journal   (Followers: 2)
ASN Neuro     Open Access   (Followers: 2)
Assessment     Hybrid Journal   (Followers: 17)
Assessment and Treatment of Child Psychopathology and Developmental Disabilities     Full-text available via subscription   (Followers: 4)
Atherosclerosis     Hybrid Journal   (Followers: 13)
Atherosclerosis Supplements     Hybrid Journal   (Followers: 1)
Audiology and Neurotology     Full-text available via subscription   (Followers: 9)
Audiology and Neurotology Extra     Open Access   (Followers: 1)
Australasian Journal of Neuroscience     Open Access   (Followers: 2)
Australasian Psychiatry     Hybrid Journal   (Followers: 18)
Australian & New Zealand Journal of Psychiatry     Hybrid Journal   (Followers: 29)
Autism & Developmental Language Impairments     Open Access   (Followers: 12)
Autism and Developmental Disorders     Open Access   (Followers: 9)
Autism Research     Hybrid Journal   (Followers: 52)
Autism Research and Treatment     Open Access   (Followers: 34)
Autism's Own     Open Access   (Followers: 6)
Autism-Open Access     Open Access   (Followers: 8)
Autonomic Neuroscience     Hybrid Journal   (Followers: 10)
Autonomy, the Critical Journal of Interdisciplinary Autism Studies     Open Access   (Followers: 5)
Avicenna Journal of Neuro Psycho Physiology     Open Access  
Basal Ganglia     Hybrid Journal  
Basic and Clinical Neuroscience     Open Access   (Followers: 9)
Behavior Therapy     Hybrid Journal   (Followers: 54)
Behavioral and Brain Functions     Open Access   (Followers: 3)
Behavioral and Brain Sciences     Hybrid Journal   (Followers: 38)
Behavioral and Cognitive Neuroscience Reviews     Hybrid Journal   (Followers: 26)
Behavioral Healthcare     Full-text available via subscription   (Followers: 8)
Behavioral Medicine     Hybrid Journal   (Followers: 9)
Behavioral Sciences     Open Access   (Followers: 4)
Behavioral Sleep Medicine     Hybrid Journal   (Followers: 15)
Behavioural Brain Research     Hybrid Journal   (Followers: 19)
Behavioural Neurology     Open Access   (Followers: 9)
Behavioural Processes     Hybrid Journal   (Followers: 9)
Biological Psychiatry     Hybrid Journal   (Followers: 53)
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging     Hybrid Journal   (Followers: 11)
Biologically Inspired Cognitive Architectures     Hybrid Journal   (Followers: 2)
Biology of Mood & Anxiety Disorders     Open Access   (Followers: 6)
Biomarkers in Neuropsychiatry     Open Access   (Followers: 1)
BioMolecular Concepts     Open Access   (Followers: 2)
Bipolar Disorders     Hybrid Journal   (Followers: 11)
BJPsych Advances     Full-text available via subscription   (Followers: 57)
BJPsych Bulletin     Full-text available via subscription   (Followers: 19)
BJPsych International     Open Access   (Followers: 2)
BJPsych Open     Open Access   (Followers: 3)
Blue Books of Neurology     Full-text available via subscription   (Followers: 1)
BMC Neurology     Open Access   (Followers: 22)
BMC Neuroscience     Open Access   (Followers: 17)
BMC Psychiatry     Open Access   (Followers: 38)
Borderline Personality Disorder and Emotion Dysregulation     Open Access   (Followers: 10)
Brain     Hybrid Journal   (Followers: 78)
Brain & Life     Full-text available via subscription   (Followers: 3)
Brain and Behavior     Open Access   (Followers: 15)
Brain and Cognition     Hybrid Journal   (Followers: 38)
Brain and Development     Full-text available via subscription   (Followers: 5)
Brain and Language     Hybrid Journal   (Followers: 68)
Brain and Mind     Hybrid Journal   (Followers: 6)
Brain and Neuroscience Advances     Open Access  
Brain Behavior and Evolution     Full-text available via subscription   (Followers: 9)
Brain Communications     Open Access   (Followers: 3)
Brain Disorders & Therapy     Open Access   (Followers: 1)
Brain Hemorrhages     Open Access   (Followers: 1)
Brain Imaging and Behavior     Hybrid Journal   (Followers: 9)
Brain Impairment     Full-text available via subscription   (Followers: 2)
Brain Informatics     Open Access   (Followers: 1)
Brain Injury     Hybrid Journal   (Followers: 31)
Brain Pathology     Hybrid Journal   (Followers: 5)
Brain Research     Hybrid Journal   (Followers: 26)
Brain Research Bulletin     Hybrid Journal   (Followers: 5)
Brain Sciences     Open Access   (Followers: 5)
Brain Stimulation     Hybrid Journal   (Followers: 8)
Brain Structure and Function     Partially Free   (Followers: 9)
Brain Topography     Hybrid Journal   (Followers: 2)
Brain, Behavior, and Immunity     Hybrid Journal   (Followers: 11)
Brazilian Journal of Pain (BrJP)     Open Access  
British Journal of Mental Health Nursing     Full-text available via subscription   (Followers: 23)
British Journal of Music Therapy     Hybrid Journal   (Followers: 8)
British Journal of Pain     Hybrid Journal   (Followers: 28)
British Journal of Psychiatry     Hybrid Journal   (Followers: 248)
British Journal of Social Psychology     Full-text available via subscription   (Followers: 41)
Canadian Journal of Behavioural Science     Full-text available via subscription   (Followers: 7)
Canadian Journal of Counselling and Psychotherapy / Revue canadienne de counseling et de psychothérapie     Hybrid Journal   (Followers: 10)
Canadian Journal of Neurological Sciences     Full-text available via subscription  
Canadian Journal of Psychiatry     Hybrid Journal   (Followers: 27)
Cannabis and Cannabinoid Research     Hybrid Journal   (Followers: 2)
Case Reports in Neurological Medicine     Open Access   (Followers: 1)
Case Reports in Neurology     Open Access   (Followers: 5)
Case Reports in Psychiatry     Open Access   (Followers: 17)
Cellular and Molecular Life Sciences (CMLS)     Hybrid Journal   (Followers: 5)
Central Nervous System Agents in Medicinal Chemistry     Hybrid Journal   (Followers: 1)
Cephalalgia     Hybrid Journal   (Followers: 8)
Cerebellum & Ataxias     Open Access   (Followers: 1)
Cerebral Cortex     Hybrid Journal   (Followers: 56)
Cerebrovascular Diseases     Full-text available via subscription   (Followers: 3)
Cerebrovascular Diseases Extra     Open Access  
Child and Adolescent Psychiatry and Mental Health     Open Access   (Followers: 28)
Child Neurology Open     Open Access   (Followers: 5)
Child Psychiatry & Human Development     Hybrid Journal   (Followers: 12)
Chinese Neurosurgical Journal     Open Access  
Chronic Stress     Open Access  
Ciencia Cognitiva     Open Access   (Followers: 3)
Clínica e Investigación en Arteriosclerosis     Full-text available via subscription  
Clinical and Experimental Neuroimmunology     Hybrid Journal   (Followers: 1)
Clinical and Translational Neuroscience     Open Access  
Clinical EEG and Neuroscience     Hybrid Journal   (Followers: 6)
Clinical Journal of Pain     Hybrid Journal   (Followers: 19)
Clinical Medicine Insights : Psychiatry     Open Access   (Followers: 10)
Clinical Neurology and Neurosurgery     Hybrid Journal   (Followers: 16)
Clinical Neuropathology     Full-text available via subscription   (Followers: 1)
Clinical Neuropharmacology     Hybrid Journal   (Followers: 4)
Clinical Neurophysiology     Full-text available via subscription   (Followers: 13)
Clinical Neurophysiology Practice     Open Access  
Clinical Neuropsychiatry     Open Access   (Followers: 2)
Clinical Practice & Epidemiology in Mental Health     Open Access   (Followers: 1)
Clinical Psychological Science     Hybrid Journal   (Followers: 12)
CNS & Neurological Disorders - Drug Targets     Hybrid Journal   (Followers: 3)
CNS Spectrums     Hybrid Journal   (Followers: 3)
Cognition     Hybrid Journal   (Followers: 231)
Cognitive and Behavioral Neurology     Hybrid Journal   (Followers: 10)
Cognitive and Behavioral Practice     Hybrid Journal   (Followers: 13)
Cognitive Neurodynamics     Hybrid Journal   (Followers: 2)
Cognitive Neuropsychiatry     Hybrid Journal   (Followers: 1)
Cognitive Neuropsychology     Hybrid Journal   (Followers: 40)
Cognitive Neuroscience     Hybrid Journal   (Followers: 29)
Cognitive Therapy and Research     Hybrid Journal   (Followers: 7)
Cognitive, Affective, & Behavioral Neuroscience     Full-text available via subscription   (Followers: 24)
Community Mental Health Journal     Hybrid Journal   (Followers: 18)
Comprehensive Psychiatry     Open Access   (Followers: 13)
Computational Brain & Behavior     Hybrid Journal  
Computational Psychiatry     Open Access   (Followers: 2)
Consciousness and Cognition     Hybrid Journal   (Followers: 39)
Contemporary Neurosurgery     Full-text available via subscription   (Followers: 4)

        1 2 3 4 5 | Last

Similar Journals
Journal Cover
Acta Neurologica Belgica
Journal Prestige (SJR): 0.376
Citation Impact (citeScore): 1
Number of Followers: 3  
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0300-9009 - ISSN (Online) 2240-2993
Published by Springer-Verlag Homepage  [2626 journals]
  • Topographic changes measured by the swept source optical coherence
           tomography in retinal nerve fiber layer, optic nerve head and macula in
           children with migraine
    • Abstract: Abstract As a vascular-inflammatory disease, migraine affects the brain and some other organs, such as the eye. The aim of this study was to measure and compare the peripapillary retinal nerve fiber layer (RNFL) thickness, macular ganglion cell layer thickness and optic nerve head parameters to detect structural damage in children with migraine using swept-source optical coherence tomography. Twenty-four children with migraine in the painless period and 26 controls were included in the study. The vast majority of the groups consisted of females (75% for patients and 77% for controls). Certain RNFL quadrants and optic disc parameters revealed significant differences between the patients and controls. In the right and left eyes of children with migraine, nasal quadrant RNFL was significantly thicker than that in healthy subjects (88.82 ± 11.03 vs 77.80 ± 13.77, P = 0.004 for right eyes and 87.71 ± 11.79 vs 77.80 ± 13.77, P = 0.01 for left eyes). Temporal quadrant RNFL in the left eyes was thinner (78.67 ± 9.57 vs 84.44 ± 9.68, P = 0.04). Disc area in the left eyes of the patients was greater (2.29 ± 0.46 vs 1.94 ± 0.28, P = 0.003). There were significant expansions in cup volumes in favor of the patients for right and left eyes (0.15 ± .0.19 vs 0.05 ± 0.05, P = 0.03 and 0.17 ± 0.14 vs 0.05 ± 0.05, P = 0.001, respectively). The only significant difference between the left and right eyes of the migraineurs was the RNFL thickness in the superior quadrant. Ganglion cell layer thickness did not differ between the right eyes, left eyes and controls. In conclusion, children with migraine showed significant variations in specific RNFL and optic disc parameters compared to control subjects.
      PubDate: 2019-03-20
  • Management of acute mitochondriopathy and encephalopathy syndrome in
           pediatric intensive care unite: a new clinical entity
    • Abstract: Abstract Acute mitochondriopathy and encephalopathy syndrome (AMES) is described differently by different authors in the literature. As a new clinical entity, we aimed to present the clinical signs and symptoms, diagnosis and treatment algorithm of our patients with AMES. 56 patients aged between 2 months and 18 years who were followed up in pediatric intensive care units of Konya Training and Research Hospital and Selcuk University Medical Faculty Hospital, between January 2010 and June 2017 were included. Patients’ data were obtained retrospectively from the intensive care unit patient files. 34 (60.7%) of the patients were male and 22 (39.3%) were female. The median age of our patients was 10.0 months. At the time of admission, 42 (75%) of the patients had fever, 35 (62.5%) vomiting, 27 (48.2%) abnormal behaviour and agitation and 28 (50%) convulsion. The etiological classification of patients with AMES was divided into four groups as infection, metabolic disorder, toxic, and hypoxic-ischemic. 39 (69.6%) patients were found to have infection, 10 (17.9%) patients hypoxia, 7 (12.5%) patients metabolic disorders. AMES occurs rarely, but should be kept in mind in the differential diagnosis of patients with any encephalopathy of unknown origin especially in those with a history of ingestion of drugs, previous viral infection and vomiting. Early recognition and treatment is imperative to reduce morbidity and mortality in children with AMES.
      PubDate: 2019-03-18
  • The neurological aspects related to POGZ mutation: case report and review
           of CNS malformations and epilepsy
    • PubDate: 2019-03-16
  • Amyotrophic lateral sclerosis due to a SOD1 mutation and X-linked
           recessive bulbospinal neuronopathy in a single family
    • PubDate: 2019-03-16
  • The current and emerging therapeutic approaches in drug-resistant epilepsy
    • Abstract: Abstract Epilepsy is a neurologic disorder consisting of recurrent spontaneous seizures. Antiepileptic drugs administration is the most commonly used therapeutic strategy in the management of epilepsy. However, 20–30% of epilepsy patients have seizure episodes that are not controlled by these medicines (drug-resistant epilepsy). The management of drug-resistant epilepsy, especially in the children, is challenging and can cause economic and social problems, and lower the patients’ quality of life, cognition, and mood. Several therapeutic approaches for drug-resistant epilepsy are available including surgical methods, neurostimulation treatments, and diet therapies which lead to diminishing the epileptic seizures. An increasing number of novel and potential therapeutic approaches such as gene therapy, gene editing, cell therapy, exosome therapy, and molecular network targeting have also been explored. The present study is aimed to review these current and emerging therapeutic approaches for drug-resistant epilepsy.
      PubDate: 2019-03-13
  • The clinical and radiological features of cisternal and pericallosal
    • Abstract: Purpose To demonstrate the clinical and radiological features of pericallosal and cisternal lipomas and to compare these two groups in terms of radiological and clinical features. Methods This retrospective study included 23 patients diagnosed with pericallosal and cisternal lipoma between 2010 and 2017. The patients comprised 12 females and 11 males with a mean age of 38.8 years (range 12–69 years). Magnetic resonance imaging was applied to all the patients. Computed tomography (CT) was also performed in 10 patients. Results 9 lesions were pericallosal and 14 were cisternal (7 were right quadrigeminal cistern, 3 were left quadrigeminal cistern, 1 was interpeduncular cistern, 1 was left cerebellopontine cistern, 1 was right cerebellopontine cistern, and 1 was supracerebellar cistern). The mean size of the lesions was 18.7 ± 10 mm. The shape of the lesions was curvilinear in 10 patients (43.5%) and tubulonodular in 13 patients (56.5%). The mean CT density of the lesions was − 87.7 ± 25.6 HU. The size of pericallosal lipomas (mean 27.5 mm) was statistically significantly larger than that of cisternal lipomas (mean 13.1 mm) (p = 0.001). No statistically significant difference was determined between the two groups in terms of lesion shape (p = 0.478), gender (p = 0.707), age (p = 0.639), and symptoms (p = 0.084). Conclusions In this study, the incidence of pericallosal lipomas was 0.011% and the incidence of cisternal lipomas was 0.017%. Although rare, the knowledge of the clinical and radiological features of pericallosal and cisternal lipomas will play an important role in the accurate diagnosis and follow-up of the patient.
      PubDate: 2019-03-13
  • Clinical use of 99m Tc-HMPAO-labeled platelets in cerebral sinus
           thrombosis imaging
    • Abstract: Abstract Magnetic resonance imaging (MRI) and computed tomography (CT) are not always conclusive for the detection of cerebral venous sinus thrombosis (CVST). 99mTc-HMPAO-labeled platelets may be useful in cases with high clinical suspicion. Three patients with headaches with or without intraparenchymal hemorrhage that were highly suspected to have CVST, despite inconclusive anatomical imaging, were selected for inclusion in the study. Platelets were extracted by two rounds of centrifugation from 49 ml of the patient’s whole blood. The platelets were labeled with 99mTc-HMPAO and any unbound 99mTc was removed by centrifugation. The re-suspension of 99mTc-HMPAO-labeled platelets in cell-free plasma was reinjected into the patients. After 2 h, planar and single photon emission computed tomography (SPECT) images of the head were obtained. Extensive clots were detected in all three patients, illustrated in the planar image and even clearer in the SPECT images. We propose that 99mTc-HMPAO-labeled platelet scan is a favorable imaging method for patients suspected to have CVST with inconclusive CT and MRI results.
      PubDate: 2019-03-13
  • A case of useless hand as a first demyelinating event
    • PubDate: 2019-03-09
  • Intravascular large B-cell lymphoma: a forgotten stroke
    • PubDate: 2019-03-08
  • Posttraumatic retroclival hematoma: a case report
    • PubDate: 2019-03-08
  • CSF biomarkers and amyloid PET: concordance and diagnostic accuracy in a
           MCI cohort
    • Abstract: Abstract Brain amyloid deposition is one of the main hallmarks of Alzheimer’s disease (AD) and two approaches are available for assessing amyloid pathology in vivo: cerebrospinal fluid (CSF) biomarkers levels and amyloid load visualized by amyloid beta positron emission tomography imaging (Amy-PET) probes. We aimed to investigate the concordance between CSF biomarkers and Amy-PET in a memory clinic cohort. Moreover, using a proper clinical follow-up, we wanted to assess the diagnostic accuracy of CSF and PET biomarkers in predicting the progression of patients with mild cognitive impairment (MCI) to AD dementia. We included 31 MCI patients who underwent [18F]florbetaben PET and CSF sampling (Aβ1–42, t-Tau, p-Tau). A semiquantitative visual scan assessment was used to quantify amyloid deposition in 5 brain regions, rating from 1 (negative), to 2 and 3 (positive). CSF biomarkers were considered abnormal if: Aβ1–42 < 600 pg/ml, p-Tau/Aβ1–42 > 0.08 and t-Tau/Aβ1–42 > 0.52. We also applied less lenient cutoffs of 550 pg/ml and 450 pg/ml for Aβ1–42. The concordance rate was 77% between Amy-PET and CSF Aβ1–42 levels, and 89% between Amy-PET and p-Tau/Aβ1–42 and t-Tau/Aβ1–42. According to the clinical follow-up, Amy-PET (sensitivity [SE] 93.7%, specificity [SP] 80%) exhibited the best diagnostic accuracy in discriminating AD from non-AD, followed by p-Tau/Aβ1–42 ratio and t-Tau/Aβ1–42 ratio (SE 93.7%, SP 66.6%), and Aβ1–42 levels (SE 81%, SP 60%). The regional uptake of [18F]florbetaben PET in the precuneus and the striatum showed the best SP (86.6%). In discordant cases, the clinical diagnosis was most often in agreement with PET results. In general, concordance between CSF biomarkers and Amy-PET was good, especially when the ratios between CSF amyloid and Tau biomarkers were used. However, Amy-PET proved to be superior to CSF Aβ1–42 in terms of diagnostic accuracy for AD, with the possibility to further increase its specificity by focusing the analysis in specific areas such as the precuneus/posterior cingulate cortex and the striatum.
      PubDate: 2019-03-07
  • Nocturnal blood pressure changes in Parkinson’s disease: correlation
           with autonomic dysfunction and vitamin D levels
    • Abstract: Abstract Nocturnal blood pressure (BP) changes are an indicator of autonomic dysfunction. We aim to investigate the correlation between nocturnal blood pressure (BP) variability, vitamin D levels and Parkinson’s disease severity (PD) in this study. Thirty-five patients with PD participated in the study. Disease severity was evaluated by United Parkinson’s Disease Rating Scale (UPDRS) and Hoehn and Yahr Scale (HYS). Equivalent levodopa dose was calculated and 25-hydroxyvitamin D levels were measured. The Non-Motor Symptom Questionnaire (NMSQ) was applied to all patients. Ambulatory BP monitoring for 24 h was established. Patients were divided into three groups according to nocturnal BP results: dippers (normal finding—a decline in mean nighttime BP of more than 10%); non-dippers (pathological—a decline in mean nighttime BP of less than 10%); reverse dippers (pathological—an increase in mean nighttime BP) .The mean score of the NMSQ was higher in the group with HYS > 2 (p = 0.050). Four patients were dipper, 17 patients were non-dipper and 16 patients were reverse dipper. There was no significant difference between the three groups in terms of age, gender, disease duration, age of the disease onset, disease stage, disease duration, dopamine agonist usage, levodopa equivalent dose, vitamin D level and NMSQ scores. NMSQ scores are high in advanced PD. Ambulatory BP monitoring is useful in detecting autonomic dysfunction. The number of patients with non-dipping and reverse dipping is high in PD, independent from PD severity, drug dose, vitamin D and the other NMS symptoms.
      PubDate: 2019-03-07
  • Ipsilateral supranuclear lingual palsy due to caudal paramedian pontine
    • PubDate: 2019-03-06
  • Contralateral levodopa-induced hemichorea in a patient with severe
           asymmetric Parkinson’s disease
    • PubDate: 2019-03-06
  • Skull base osteomyelitis: factors implicating clinical outcome
    • Abstract: Abstract Skull base osteomyelitis is a serious disease with a high risk of complications including neuroinfection. Typically, the inflammation of the skull base results from infection from neighboring tissues. In case of malignant otitis externa, inflammation disseminates from the external auditory canal. In this study, we present our experience with seven patients diagnosed with skull base osteomyelitis that began with otitis externa and have been treated in our department for the last 10 years. Department Patient Database was searched for the diagnosis skull base osteomyelitis. The search covered the last 10 years. The search revealed seven patients who met the above-described criteria. Medical records of those patients were carefully analyzed including age, gender, symptoms and signs, diagnostics details, treatment, performed procedures, number of hospitalization days, comorbid diseases, and complications including any cranial nerve palsy. Detailed analysis of medical records of patients included in this study showed that skull base osteomyelitis presents a challenge for diagnosis and treatment. Treatment strategy requires prolonged aggressive intravenous antibiotic therapy, and in some cases combined with surgical intervention. Cranial nerve paresis indicates progression of the disease and is associated with longer hospital stay. Similar relationship is observed in patients with skull base osteomyelitis that required surgery. Diabetes in patient’s medical history may complicate the healing process. Diabetes, neural involvement, and surgery may overlap each other resulting in longer hospital stay. Cranial nerve paresis may not resolve completely and some neural deficits become persistent.
      PubDate: 2019-03-06
  • The efficacy and safety of nerve combing for trigeminal neuralgia without
           neurovascular compression
    • Abstract: Objective The purpose of our study was to review and evaluate the efficacy and safety of nerve combing without neurovascular decompression for trigeminal neuralgia. Methods A retrospective review of 298 patients with trigeminal neuralgia between August 2007 and August 2016 was conducted. The patients were divided into two groups: the A group was treated by nerve combing (34 patients) and the B group received microvascular decompression (264 patients). Surgical outcomes and postoperative complications were compared between the two groups. Results Pain was completely relieved in 88.2% of group A patients and 92.8% of group B after surgery. The median duration of follow-up was 60 months (range 10–115 months) in group A and 62 months (range 12–118 months) in group B. 72.7% and 86.4% of cases were completely relieved in groups A and B, respectively. There were no statistically significant differences in the surgical outcomes between the two groups. Almost all patients experienced some degree of numbness or hypesthesia (76.5%). The rate of facial numbness in group A was significantly higher than that in group B. Conclusion This study demonstrated that nerve combing without neurovascular decompression is a safe and effective treatment for trigeminal neuralgia. However, a majority of patients treated with nerve combing experienced some degree of facial numbness.
      PubDate: 2019-03-06
  • Predictive value of laboratory parameters in childhood migraine
    • Abstract: Abstract Migraine is a neurovascular disease characterized by inflammation of the cerebral and extra cerebral vessels and appears in the form of attacks. Although the pathophysiology of migraine is not fully known, the data obtained because of long-term studies reliably support the presence of a potential relationship between migraine pathogenesis and platelet biology. The aim of this study was to investigate the effect of migraine on MPV and other blood parameters as well as the relationship between the hematologic parameters and characteristics of the headache and whether they possess diagnostic value as inflammation and platelet biology play a fundamental role in the disorder. The study group consisted of 56 patients who were followed up and treated with a diagnosis of migraine and 45 healthy patients. The median creatinine, CRP and TSH values of the children in the migraine group were found to be statistically significantly higher than the healthy control group. Serum iron levels of the migraine group were found to be statistically significantly lower than the control group. No statistically significant difference was found between the two groups in terms of MPV. However, when we examined only the patient group, we found MPV to be statistically significantly higher in girls. Increased MPV and decreased serum iron levels may be related to migraine. More comprehensive studies including a larger population are required to evaluate the specific parameters that may guide the follow-up and treatment of the disorder with simple tests to be used in routine practice and to elucidate the underlying pathophysiology.
      PubDate: 2019-03-06
  • Lacosamide in patients with intellectual disability and refractory
    • Abstract: Abstract The objective of this study was to evaluate the tolerability and efficacy of lacosamide (LCM) in residential patients at our epilepsy centre. We assessed retrospectively 80 patients (mean age 36.2 years, range 18–63 years; 29 female) with intellectual disability (ID) and drug-resistant epilepsy using an industry-independent, non-interventional study design based on standardised seizure records. Evaluation, including calculation of retention rate, was carried out for the intervals 3–6, 9–12 and 21–24 months after LCM initiation. The Clinical Global Impression scale (CGI) was used to allow assessment of qualitative changes in seizure severity and clinical status. CGI improved for 61% of the patients. The responder rate was 48%; ten patients (13%) became seizure free. The response was not related to the degree of ID. The retention rates after 12 and 24 months were 71% and 65%, and were significantly lower in patients taking other sodium-channel blockers (SCBs; 76% vs. 55%). The occurrence of adverse events (AEs) was related to the administration of concomitant SCBs (48% with SCBs vs. 26% without). Sedation (15%), ataxia (13%), vertigo (11%), and nausea (9%) were the commonest AEs. While 60% of our patients had concomitant psychiatric diagnosis, we found no relevant effect of this on challenging behaviour. Adjunctive LCM may provide an antiepileptic treatment option for patients with ID with or without additional psychiatric diagnosis. The occurrence of AEs and the LCM retention rate were affected by concomitant SCB use but not by psychiatric comorbidity.
      PubDate: 2019-03-06
  • The relationship between motor performance and femoral cartilage thickness
           in children with Down syndrome
    • Abstract: Abstract Down syndrome (DS) is a genetic disorder associated with mental and motor developmental delays in childhood. The aim of this study was to investigate the relationship of the femoral cartilage thickness with motor performance in children with Down syndrome (DS). A total of 39 children with DS in the age range of 12–42 months were included in the study (female/male: 21/18; mean age: 23.4 ± 8.2 months). Femoral cartilage thickness was measured with ultrasound in the medial and lateral condyles and intercondylar areas of both knees. Gross motor subtest scaled scores of the Bayley Scales of Infant and Toddler Development III were used for the motor performance assessment. There was a positive correlation between the gross motor scaled scores and the femoral cartilage thickness in both knee joints (p < .05; r = 0.415 for the right medial condyle; r = 0.323 for the right lateral condyle; r = 0.339 for the right intercondylar area; r = 0.369 for the left medial condyle; r = 0.364 for the left lateral condyle, and r = 0.590 for the left intercondylar area). The study demonstrated that the femoral cartilage thickness was positively correlated with gross motor functioning in children with DS.
      PubDate: 2019-03-06
  • Encephalopathy with extensive reversible restricted diffusion within the
           white matter or other problem'
    • PubDate: 2019-03-05
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Tel: +00 44 (0)131 4513762

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