Subjects -> BEAUTY CULTURE (Total: 22 journals)
    - BEAUTY CULTURE (20 journals)
    - PERFUMES AND COSMETICS (2 journals)

BEAUTY CULTURE (20 journals)

Showing 1 - 19 of 19 Journals sorted alphabetically
Achiote.com - Revista EletrĂ´nica de Moda     Open Access  
American Journal of Cosmetic Surgery     Hybrid Journal   (Followers: 5)
Australian Advanced Aesthetics     Full-text available via subscription   (Followers: 4)
Critical Studies in Fashion & Beauty     Hybrid Journal   (Followers: 8)
Dress     Hybrid Journal   (Followers: 9)
Fashion and Textiles     Open Access   (Followers: 11)
Flavour and Fragrance Journal     Hybrid Journal   (Followers: 3)
Ground Breaking     Open Access   (Followers: 1)
Instyle     Full-text available via subscription  
International Journal of Cosmetic Science     Hybrid Journal   (Followers: 8)
Materiali di Estetica     Open Access  
Media, Culture & Society     Hybrid Journal   (Followers: 43)
Mind Culture and Activity     Hybrid Journal   (Followers: 10)
Parallax     Hybrid Journal   (Followers: 8)
Professional Beauty     Full-text available via subscription   (Followers: 5)
Science as Culture     Hybrid Journal   (Followers: 10)
The Rose Sheet     Full-text available via subscription  
Transactions of the Burgon Society     Open Access  
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American Journal of Cosmetic Surgery
Number of Followers: 5  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0748-8068 - ISSN (Online) 2374-7722
Published by Sage Publications Homepage  [1174 journals]
  • Concepts in Hip Implant Body Contouring: Patient Evaluation & Implant
           Fabrication

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      Authors: Robert J. Troell, Barry Eppley, Shahin Javaheri
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Introduction: One of the most requested aesthetic procedures is body contouring using liposuction. Adjunctive procedures using fat grafting can provide enhancement in most body areas, commonly used in both gluteal and hip augmentation. Performing processing and enrichment to optimize fat transfer survival can avoid the use of body implants. When there is insufficient fat for the desired degree of augmentation, silastic implant placement is an alternative treatment. Much has been written in the medical cosmetic literature regarding gluteal and breast implants, but nothing in terms of hip silastic implants. Material and Methods: Hip implant patient selection, the body frame analysis, associated enhancing body contouring procedures, implant design and fabrication, and implant surgical placement are analyzed. In 3 different cosmetic surgery practices, methods of patient analysis and the process of creating a custom hip implant is presented. Techniques and protocols in the use of fat grafting in association with both gluteal and hip implants are elucidated. Results: The minimally manipulating fat maneuvers to increase fat survival are detailed. This paper defines the process of planning, designing, and fabricating a custom hip implant with significant patient input. By definition, patient-specific or custom implants can be any shape, size, and projection. The patient and surgeon provide the implant fabrication company a paper tracing of the surface area of the proposed implant along with the maximum projection. Engineering creates a 2-dimensional drawing using a computational software for intelligent system design or CAD. The implants are fabricated with input from the surgeon on silastic durometer, implant alterations to lower weight and enhance ease of folding for placement, and shape. Caveats and pitfalls in surgical planning, implant design, fabrication, and surgical placement are identified. Discussion: Body contouring using ultrasound liposuction may provide the desired aesthetic result. When augmentation is requested, fat transfer is the preferred initial procedure. If there is an insufficient volume of fat to augment both the buttocks and hip area, hip fat grafting is preferred to avoid a hip alloplastic implant. The reason for this treatment recommendation is to avoid the hip implant with a higher risk profile. Once the indication for the hip implant is confirmed, usually because of either inadequate presence of fat or a desired maximum hip projection that cannot be attained by fat grafting alone, the body shape analysis is finalized. Conclusion: Custom silastic hip implants are designed, fabricated, and surgically placed to provide the patient desired cosmetic hip augmentation.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-06-23T12:40:41Z
      DOI: 10.1177/07488068221101229
       
  • Cosmetic Surgery Regulation in Australia: Who Is to Be
           Protected—Surgeons or Patients'

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      Authors: Patrick Tansley, Daniel Fleming, Tim Brown
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      The practice of cosmetic surgery is of immense interest across the western world. In Australia, its regulation is currently the subject of three separate administrative processes, all due to report by mid-2022. Cosmetic surgery is typically dealt with at a superficial level by the media and sometimes misrepresented by medical commentators. This article details relevant issues for consideration and in relation to their complexities, which may be of interest to readers in other jurisdictions such as the United States.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-06-22T09:14:04Z
      DOI: 10.1177/07488068221105360
       
  • Ex Vivo Versus In Vivo Liposuction Hemolysis Index in High-Definition
           Liposuction and Body Contouring

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      Authors: Arian Mowlavi, Zachary Sin, Stephanie Young, Chelsea Sahami, Varun Sharma
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Background:Ex vivo liposuction is a novel technique wherein tissues that are preoperatively planned for excision can be liposuctioned in a sterile manner after removal from the patient. Excised tissues are routinely obtained during a tummy tuck or variant, lateral thigh tuck, buttock tuck, brachioplasty, upper body tuck, and medial thigh tuck. These tucking procedures are performed when moderate to severe skin redundancy is present in patients undergoing body contouring. Traditionally, these tissues were first liposuctioned prior to being excised, termed in vivo liposuction. However, we have developed ex vivo liposuction protocols wherein the tissues are liposuctioned after they have been excised off the patient. Routine processing of harvested fat focuses on minimizing blood products in the aspirate prior to injection. This is because blood products are felt to contain pro-inflammatory products that negatively affect fat graft take. We hypothesized that fat collected by ex vivo technique provides a less bloody harvest than fat collected by in vivo technique.Materials and Methods:We quantitated blood concentrate of ex vivo versus in vivo fat aspirate by comparing the hemolysis index in 14 consecutive patients undergoing high-definition liposuction and body contouring.Results:Comparison of hemolysis index demonstrated significant reduction in blood concentrate in ex vivo versus in vivo fat aspirate. In vivo hemolysis index demonstrated a larger median than ex vivo hemolysis index. These results confirm our clinical observation that fat harvested by ex vivo liposuction is cleaner and less blood-tinged than fat harvested by in vivo liposuction.Conclusion:No patients experienced complications related to fat graft infection nor fat emboli. Ex vivo liposuction has proven a safe and less blood-tinged technique for harvesting fat in patients who require excisional procedures.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-06-22T09:10:04Z
      DOI: 10.1177/07488068221104568
       
  • Lipoabdominoplasty: Comparing Ultrasound-Assisted and Power-Assisted
           Techniques

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      Authors: Robert J. Troell
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Introduction: Optimizing the abdomen aesthetic appearance may combine liposculpture, abdominoplasty, and postsurgical noninvasive body sculpting. The abdominoplasty traditional technique highlights abdominal flap undermining. The Avelar or Saldana lipoabdominoplasty’s technique modifications use liposuction and the absence of undermining of the abdominal wall flap. This method maintains abdominal wall vascularization and lessens complications. Two commonly employed liposuction techniques are power-assisted and ultrasound-assisted liposuction. Combining power-assisted technology with the Separation, Aspiration, Fat Equalization (SAFE) liposuction process has improved aesthetic results and reduced complications. Separation, Aspiration, Fat Equalization liposuction process enrolls separation, aspiration, and fat equalization steps. Ultrasound-assisted liposuction advantages include high-definition body sculpting through maximum fat removal and skin tightening with less blood loss and viable fat for grafting. This clinical study evaluated a comprehensive surgical protocol for lipoabdominoplasty designed to minimize complications. In addition, the study assessed aesthetic outcome and complication differences comparing the use of ultrasound-assisted versus power-assisted liposuction. Materials and Methods: This is a retrospective study in a single surgeon’s private cosmetic practice in 2 practice locations in patients undergoing a modified lipoabdominoplasty technique over a 2-year period. Results: Modified lipoabdominoplasty combining power-assisted technology with SAFE liposuction (n = 30) compared to those using ultrasound-assisted liposuction (n = 20) revealed similar complication rates. Surgeon observation revealed better skin contour smoothness, more abdominal definition and skin tightening with less bruising when using ultrasound liposuction. The comprehensive surgical protocol designed to minimize perioperative complications was implemented on each patient and resulted in no medical errors and a low major and minor complication rate. Conclusions: The lipoabdominoplasty surgical protocol provides surgeon’s comprehensive preoperative, intraoperative, and postoperative guidelines to minimize complications. Higher body mass index increased the complication rate. The aesthetic outcome using ultrasound-assisted liposuction appeared to yield better aesthetic sculpted appearance with less bruising compared to power-assisted technology.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-06-15T09:39:27Z
      DOI: 10.1177/07488068221099153
       
  • Suture Cheek Suspension Augments Periorbital Aesthetic Rehabilitation in
           Facial Nerve Palsy

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      Authors: Natalie A. Homer, Justin Karlin, Alison H. Watson, Marie Somogyi, Emily Bratton, Robert A. Goldberg, Tanuj Nakra
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Purpose: Facial nerve palsy may lead to significant functional facial and ocular morbidity. Soft tissue resuspension may improve both functional and aesthetic defects. We have adapted a minimally invasive midface suspension, which may be easily combined with routine paretic periocular rehabilitation to optimize outcomes. Methods: A retrospective review of patients with unilateral facial nerve palsy who underwent midcheek release and suture suspension simultaneous with periocular surgical rehabilitation at 2 surgical centers was performed. A temporal incision was made and dissection carried along the deep temporalis fascia to the lateral orbital rim. Dissection was continued subperiosteally along the anterior face of the maxilla to the piriform aperture. In severe cases, a second incision via superior buccal sulcus was utilized to maximize cheek soft tissue mobilization. Through 3 separate stab incisions along the nasolabial fold each end of a 0-0 permanent braided suture on a Keith needle was used to engage and elevate cheek soft tissues, secured at the deep temporalis fascia. Results: Seven patients (mean age 69 years) with unilateral facial nerve palsy and symptomatic facial droop underwent midface suture suspension simultaneous to eyelid reconstruction. With an average follow-up of 8.7 months, all patients demonstrated lasting improvement in facial asymmetry and reported satisfaction with their results. There were no significant postoperative complications. Conclusions: Midfacial static soft tissue resuspension is an effective minimally invasive surgical option for static facial rehabilitation in patients with facial nerve paralysis that can be performed at the time of periocular rehabilitation to enhance functional and aesthetic outcomes.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-05-03T06:17:55Z
      DOI: 10.1177/07488068221094452
       
  • A Case Report of Cosmetic Abdominoplasty in a Patient With Colostomy
           Appliance

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      Authors: Jonathan Alford, Robert Jackson, Chris Lowery
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Our patient presents with a unique case of both functional and cosmetic concerns following colectomy for the treatment of Crohn’s disease with subsequent massive weight loss following bariatric surgery. She desires abdominoplasty to address these concerns. Thorough preoperative planning and work up set the ground work for a successful procedure. We’ve shared our intraoperative approach, which has never before been published in the literature. Following her procedure, the patient had a mostly uneventful postoperative course. Her functional and cosmetic concerns were addressed with the procedure. The surgical outcome exceeded her expectations. Patients seeking body contouring surgery following bariatric surgery can be expected to increase. We suspect there may be other patients similar to ours that are experiencing similar functional and cosmetic concerns that can be addressed with cosmetic surgery. Due to the extremely unique nature of this case, we’ve shared our approach in hopes that our success can serve as a resource to other surgeons with similar patients.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-04-13T06:27:46Z
      DOI: 10.1177/07488068221079101
       
  • The Case Against Capsulectomies When Removing Silicone Breast Implants

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      Authors: Tim Brown
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Requests for removal of silicone breast implants are increasingly common. Often patients request a capsulectomy in either a total or “en bloc” form. Capsulectomy adds time, cost, and morbidity to removal of implant procedures. This article examines the reasoning given by practitioners for undertaking the procedure, and reviews the literature to examine the validity of those arguments. Except where pathology of the capsule is demonstrable (Breast implant related anaplastic large cell lymphoma, BIR-ALCL), there is currently no indication for prophylactic removal of capsules following removal of breast implants. Given the potential risks, and lack of evidence for the procedure, both patient and surgeons should be aware of the potential consequences.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-04-09T10:17:48Z
      DOI: 10.1177/07488068221088114
       
  • Novel Sublingual Analgesic Improves Patient Tolerance of Face and Body
           Radiofrequency Microneedling: A Split Face/Abdomen Study

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      Authors: Talon Maningas, Henry Ramirez, Kindall Martin
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Introduction:Radiofrequency (RF) microneedling requires minimal downtime; however, patients’ tolerance of the procedural pain can limit cosmetic results. The goal of this study was to determine the patient tolerance of RF microneedling with sufentanil sublingual tablet (SST) 30 μg and topical local anesthetic compared with topical local anesthetic alone.Materials and Methods:The study was a one-way crossover study of patients undergoing RF microneedling of the face or abdomen. Topical local anesthetic was applied 45 minutes prior to the initial procedure to one side of the face or abdomen (control side), followed by topical local anesthetic and SST administered 45 and 30 minutes, respectively, prior to the procedure on the opposite side (SST-treated side). The primary endpoint was patient completion of the procedure with additional endpoints of Richmond Agitation Sedation Scale scores, patient and provider satisfaction ratings, vital signs, oxygen saturation levels, and adverse events.Results:A total of 51 patients were enrolled averaging 44.8 ± 11.1 (SD) years of age. Forty-five percent of patients successfully completed the control side compared with 96% of patients successfully completing the SST-treated side (P < .001). Patients were less restless or agitated during the SST-treated side (6%) compared with the control side (51%; P < .001). Patient and provider satisfaction scores were significantly improved with SST (P < .001). Vital signs remained stable with SST treatment compared with the control side.Discussion:The SST is a safe and effective sublingual analgesic allowing patients to be awake and alert while increasing patient tolerance of RF microneedling as well as patient and provider satisfaction with the procedure.Conclusion:The SST is a novel analgesic that can be used in office-based settings with appropriate safety equipment available.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-04-02T04:31:23Z
      DOI: 10.1177/07488068221090080
       
  • New Insights in the Treatment of Urinary Incontinence: The Luksenburg
           System

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      Authors: Ariel Luksenburg, Juan J. Barcia, Jorge Gaviria, Roberto Sergio, Santiago Fernandez, Marco A. Pelosi, Marco A. Pelosi
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Introduction:Urinary incontinence (UI) is an important clinical problem which affects millions of women worldwide. We describe the Luksenburg system, a minimally invasive procedure for the treatment of UI in women, using platelet-rich plasma (PRP) injections and polycaprolactone (PCL) threads.Material & Methods:A total of 302 patients with UI, mean age 52, were evaluated with detailed history, examination, urinary diary, complete laboratory tests, ultrasonography, urodynamic studies, and completion of International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF). Under local anesthesia, PRP was injected through the anterior vaginal wall, and PCL threads were placed in paraurethral, suburethral, and lateral urethrovaginal spaces, using instruments developed for safe and effective performance. Patients were analyzed at 1, 2, 4, 8 weeks and 6 months posttreatment. Twenty patients were biopsied preoperatively and 60 days after treatment.Results:Symptoms, ICIQ-UI SF score, and postoperative urodynamic studies were significantly improved in 95% of patients with UI grade I, 92% of patients with UI grade II, and in 30% of UI grade III. Biopsies after treatment showed a dense connective tissue 3-dimensional mesh. No complications or adverse effects were observed. All patients declared satisfaction with results, will have the procedure again, and will recommend it.Discussion:The Luksenburg system results in strengthening of the paraurethral, suburethral, and lateral urethrovaginal spaces and the mucosa of the anterior vaginal wall. The combination of PRP injections and the placement of PCL threads create a fibrotic and absorbable mesh-like structure, aimed to increase the urethral resistance, so that under effort the intravesical pressure does not overcome the urethral pressure.Conclusions:These results support that the Luksenburg system is safe and a cost-effective alternative in patients with all grades of UI, reducing the need for invasive surgical procedures.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-03-21T10:34:54Z
      DOI: 10.1177/07488068221082374
       
  • Brazilian Buttock Lift for the Weight-Loss Patient

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      Authors: Samar Arshad, Zachary Sin, David Flores, Sean Satey, Arian Mowlavi
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Introduction:Performing optimal gluteal augmentation using traditional methods in moderate to severe weight-loss patients poses a surgical challenge as such patients typically present with (1) significant skin redundancy, (2) soft tissues containing higher density of connective tissues, and (3) buttock ptosis.Materials and Methods:Excess skin redundancy and buttock check ptosis require consideration of supplemental excisional tucking to achieve optimal results. In addition, subcutaneous tissues that maintain more connective tissue pose difficulty with fat removal using traditional liposuction techniques. As such, we present a novel surgical technique to optimally augment and shape the buttock in patients who have undergone weight-loss.Results:This procedure uses a modified lateral thigh and buttock tuck excision not only to lift the buttock cheek complex but also to create a dermal fat flap that is transposed into the upper buttock pole to achieve upper buttock fullness. The remainder of the excised tissue undergoes novel ex-vivo liposuction, which allows for simultaneous repair of the created excision line while fat is being harvested.Discussion:We present a new Brazilian buttock lift (BBL) procedure for weight-loss patients using a novel modified lateral thigh and buttock tuck with a dermal fat flap as well as ex-vivo liposuction and fat transfer. The described ex-vivo liposuction technique provides several advantages that include (1) limiting operative time, (2) allowing for maximal fat removal while avoiding unnecessary trauma to the patient, and (3) providing improved quality of fat that is less blood tinged. The lateral thigh and buttock tuck with dermal fat flap is used to eliminate buttock ptosis and augment the upper buttock. The ex-vivo harvested fat to the middle and lower buttock to complete buttock augmentation for the Brazilian buttock lift in a seamless fashion.Conclusions:In summary, we present a novel Brazilian buttock lift technique to augment the buttock in weight-loss patients that maximizes both patient safety and efficacy.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-03-21T10:33:17Z
      DOI: 10.1177/07488068221079445
       
  • Enhanced Draping for Oculoplastic Surgery to Minimize Respiratory Exposure
           During the COVID-19 Pandemic

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      Authors: Audrey Chow, Rona Z. Silkiss
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Surgeons and surgical staff operating on the face are at risk of respiratory-based infectious transmission given their proximity to the patient’s nose and mouth in the surgical field. We describe a modified sterile draping technique that creates a midface seal with inferior ventilation that minimizes surgeon and staff exposure to patient respiratory emissions and potential transmission of infectious diseases, as well as mitigates fire risk during oculoplastic surgery and other surgeries involving the upper face.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-03-19T11:29:02Z
      DOI: 10.1177/07488068221084471
       
  • Cosmetogynecological Surgery With Local Anesthesia: Preliminary Experience

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      Authors: Jack Pardo, Vicente Solá, Hernán Guzmán, Isabel Oporto
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Introduction:Although cosmetic gynecological procedures have been reported since antiquity, recent expansion made the cosmetogynecology becomes a recognized subspecialty. Presently, minimally invasive surgeries allow some of them to be performed under local anesthesia (LA). We present our preliminary experience using LA, highlighting safety and advantages.Methods:A total of 246 surgeries under local anesthesia on 185 median age patients, 39 years old (range: 14-80) between July 2020 and July 2021 in a Chilean aesthetic gynecology center, were retrospectively reviewed.Results:The most common surgery was Labiaplasty Type I, covering 40% (n = 99). Twenty percent of all patients (n = 38) underwent multiple surgeries in one surgical act. Minor complications were observed in 8% (n = 20) of surgeries, with satisfactory resolutions, without complications inherent to the use of LA or vasoconstrictors. Patients reported high degree of satisfaction, even in cases followed by labiaplasty repair or minor complication. Labiaplasty-related costs were considerably reduced compared with usual anesthetic procedure in more complex centers.Conclusion:This is the first South American report of various aesthetic genital procedures carried out under local anesthesia. In our experience, local anesthesia provided safe and effective results.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-03-15T04:59:53Z
      DOI: 10.1177/07488068211066161
       
  • Fox Eye Effect Using a Transcutaneous Mini-Eyebrow Tail Lift

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      Authors: André Borba, Matheus Rodrigues
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      The eyebrow position is a determining factor related to facial expression, especially concerning the anatomical relationship of the eyebrow with the eyelid. The changing position of the eyebrows with aging influences the individual’s expression and can give negative emotions such as loss of vitality, sadness, and tiredness, and influence facial beauty. Numerous procedures are available to the surgeon to prevent the eyebrows from falling after upper blepharoplasty or lift them in isolation. Despite the various surgical techniques undertaken to manage the eyebrow, conventional approaches are usually more aggressive procedures involving extensive skin resection at the hairline or scalp, endoscopic elevation, and temporal and coronal approaches. Given the growing search for less aggressive procedures that patients better tolerate, this study aims to describe a less invasive variation of the Castañares technique, focused on the elevation of the eyebrow’s tail, which may or may not be associated with blepharoplasty, the Surgical Fox Eye. The technique removes an ellipse of skin above the distal third of the eyebrow close to the hair bulbs and then sutures with a direct elevation of the eyebrow tail. The technique described is ideal for several cases, as it presents predictable and satisfactory clinical outcomes as to the patients’ expectations. It also presents easy healing with extensive durability with minimal chance of complications.Level of evidence:Level V—Opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-03-04T09:58:46Z
      DOI: 10.1177/07488068211070103
       
  • The Southern Surgical Arts Staple-Shape Mastopexy: A Technique for
           Improving Breast Ptosis

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      Authors: Dax Demaree, R. Chad Deal, Vincent Gardner, Carey Nease
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      This article describes the mastopexy technique as used by multiple physicians at Southern Surgical Arts. The procedure is based off the tailor-tacking technique that has been modified to improve efficiency and consistency in obtaining cosmetically pleasing results. The procedure has proven to be safe when performing in combination with augmentation and other cosmetic procedure.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-03-01T06:00:05Z
      DOI: 10.1177/07488068221074123
       
  • Combination 5-Fluorouracil and Microneedling Therapy for Wound
           Modification: A Histological Murine Study

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      Authors: Alison H. Watson, Hannah L. O’Mary, Zhenrong Cui, Susan C. Baer, Marie B. Somogyi, Natalie Homer, Sean M. Blaydon, Jonathan Huggins, John W. Shore, Vikram D. Durairaj, Tanuj Nakra
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Purpose:Microneedling has been shown to enhance the efficacy of topical 5-fluorouracil (5-FU) for the treatment of dermatologic malignancies that along with our anecdotal clinical success of combination treatments for scar modification led the authors to investigate the effect of 5-FU and microneedling on wound healing. The current study evaluates the clinical and histological impact of topical 5-FU and microneedling therapy, separately, and in combination in a murine model.Methods:This is a randomized controlled trial in which 20 mice were randomized to 4 treatment groups: group 1 (n = 5) controls, group 2 (n = 5) microneedling alone, group 3 (n = 5) 5-FU alone, and group 4 (n = 5) combination 5-FU and microneedling. The interventions of interest were carried out on postoperative day 5, 10, 15, and 20 after wound induction. The clinical and histological wound appearance was graded by blinded oculoplastic surgeons and a blinded dermatopathologist, respectively. Statistical analysis was performed using a Kruskal-Wallis test with Dunn test for individual comparisons of treatment groups.Results:Blinded grading of the wound healing appearance at early, intermediate, and late healing time points demonstrated a statistically significant difference at the intermediate time point only. Histological analysis demonstrated a relative increase in epidermal thickness, dermal inflammation, and fibrosis in the combination treatment group. Statistically significant differences among the groups were identified in the degree of lymphocytic inflammation and for the amount of granulomatous inflammation.Discussion:This study was the first of its kind to investigate combination treatment with 5-FU and microneedling on a histopathologic level. In a murine model, this combination treatment resulted in increased degrees of wound inflammation and fibrosis relative to controls, and each treatment alone suggesting a histological basis that may relate to clinical impact, although future study in this area, to better understand the impact of these changes, is needed.Conclusion:Combination treatment with 5-FU and microneedling results in a histological increase in the degree of wound inflammation and fibrosis relative to controls and each treatment alone.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-01-28T09:45:47Z
      DOI: 10.1177/07488068221074125
       
  • A Case of Unrelenting Facial Swelling

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      Authors: Lindsay Y. Chun, Paul O. Phelps
      Abstract: The American Journal of Cosmetic Surgery, Ahead of Print.
      Melkersson-Rosenthal syndrome (MRS) is an uncommon disorder with presenting symptoms that typically involve the face and orofacial structures. It is a difficult diagnosis to make, as it may present with a protracted course of seemingly unrelated dermatological, ocular, and neurological findings. This case report reviews the presentation, workup, and diagnosis of a 75-year-old woman who presented with orofacial swelling, facial palsy, and tongue fissuring that had intermittently recurred over 10 years without a unifying diagnosis. Extensive medical history, photography, laboratory workup, and radiographic imaging were performed to identify the diagnosis of MRS in this patient. Our case highlights the challenge and importance of critically evaluating and consolidating a patient’s history of their present illness, physical examination, and ancillary testing to successfully establish a unifying diagnosis, especially when the diagnosis is relatively rare and diverse in its range of affected populations and symptomatology.
      Citation: The American Journal of Cosmetic Surgery
      PubDate: 2022-01-08T07:14:36Z
      DOI: 10.1177/07488068211070113
       
 
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