Subjects -> HEALTH AND SAFETY (Total: 1464 journals)
    - CIVIL DEFENSE (22 journals)
    - DRUG ABUSE AND ALCOHOLISM (87 journals)
    - HEALTH AND SAFETY (686 journals)
    - HEALTH FACILITIES AND ADMINISTRATION (358 journals)
    - OCCUPATIONAL HEALTH AND SAFETY (112 journals)
    - PHYSICAL FITNESS AND HYGIENE (117 journals)
    - WOMEN'S HEALTH (82 journals)

CIVIL DEFENSE (22 journals)

Showing 1 - 18 of 18 Journals sorted alphabetically
Aggression and Violent Behavior     Hybrid Journal   (Followers: 348)
Canadian Journal of Remote Sensing     Full-text available via subscription   (Followers: 55)
Disaster Recovery Journal     Full-text available via subscription   (Followers: 4)
Disasters     Hybrid Journal   (Followers: 20)
Evolution, Medicine, and Public Health     Open Access   (Followers: 9)
Global & Regional Health Technology Assessment     Open Access   (Followers: 2)
International Journal of Critical Infrastructure Protection     Hybrid Journal   (Followers: 4)
International Journal of Emergency Management     Hybrid Journal   (Followers: 11)
International Journal of Emergency Services     Hybrid Journal   (Followers: 20)
International Journal of Forensic Engineering     Hybrid Journal   (Followers: 2)
International Journal of Intelligent Defence Support Systems     Hybrid Journal   (Followers: 4)
Journal of Applied Security Research     Hybrid Journal   (Followers: 3)
Journal of Health Care Law and Policy     Open Access   (Followers: 3)
Korean Journal of Defense Analysis     Hybrid Journal  
Prehospital and Disaster Medicine     Full-text available via subscription   (Followers: 8)
Risk, Hazards & Crisis in Public Policy     Hybrid Journal   (Followers: 5)
Strategic Analysis     Hybrid Journal   (Followers: 7)
Studies in Conflict & Terrorism     Hybrid Journal   (Followers: 364)
Similar Journals
Journal Cover
Global & Regional Health Technology Assessment
Number of Followers: 2  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2284-2403 - ISSN (Online) 2283-5733
Published by AboutScience Srl Homepage  [4 journals]
  • A pharmacoeconomic analysis from Italian guidelines for the management of
           prolactinomas

    • Authors: Michele Basile, Ilaria Valentini, Roberto Attanasio, Renato Cozzi, Agnese Persichetti, Irene Samperi, Alessandro Scoppola, Renata Simona Auriemma, Ernesto De Menis, Felice Esposito, Emanuele Ferrante, Giuseppe Iatì, Diego Mazzatenta, Maurizio Poggi, Roberta Rudà, Fabio Tortora, Fabio Cruciani, Zuzana Mitrova, Rosella Saulle, Simona Vecchi, Paolo Cappabianca, Agostino Paoletta, Alessandro Bozzao, Marco Caputo, Francesco Doglietto, Francesco Ferraù, Andrea Gerardo Lania, Stefano Laureti, Stefano Lello, Davide Locatelli, Pietro Maffei, Giuseppe Minniti, Alessandro Peri, Chiara Ruini, Fabio Settanni, Antonio Silvani, Nadia Veronese, Franco Grimaldi, Enrico Papini, Americo Cicchetti
      Pages: 1 - 16
      Abstract: Background: Prolactinoma, the most common pituitary adenoma, is usually treated with dopamine agonist (DA) therapy like cabergoline. Surgery is second-line therapy, and radiotherapy is used if surgical treatment fails or in relapsing macroprolactinoma. Objective: This study aimed to provide economic evidence for the management of prolactinoma in Italy, using a cost-of-illness and cost-utility analysis that considered various treatment options, including cabergoline, bromocriptine, temozolomide, radiation therapy, and surgical strategies. Methods: The researchers conducted a systematic literature review for each research question on scientific databases and surveyed a panel of experts for each therapeutic procedure’s specific drivers that contributed to its total cost. Results: The average cost of the first year of treatment was €2,558.91 and €3,287.40 for subjects with microprolactinoma and macroprolactinoma, respectively. Follow-up costs from the second to the fifth year after initial treatment were €798.13 and €1,084.59 per year in both groups. Cabergoline had an adequate cost-utility profile, with an incremental cost-effectiveness ratio (ICER) of €3,201.15 compared to bromocriptine, based on a willingness-to-pay of €40,000 per quality-adjusted life year (QALY) in the reference economy. Endoscopic surgery was more cost-effective than cabergoline, with an ICER of €44,846.64. Considering a willingness-to-pay of €40,000/QALY, the baseline findings show cabergoline to have high cost utility and endoscopic surgery just a tad above that. Conclusions: Due to the favorable cost-utility profile and safety of surgical treatment, pituitary surgery should be considered more frequently as the initial therapeutic approach. This management choice could lead to better outcomes and an appropriate allocation of healthcare resources.
      PubDate: 2024-01-09
      DOI: 10.33393/grhta.2024.2601
      Issue No: Vol. 11, No. 1 (2024)
       
  • The future of drugs distribution in the National Health System

    • Authors: Massimo Medaglia, Giuliano Buzzetti, Marco Cossolo, Paola Deambrosis, Giovanna Scroccaro
      Pages: 17 - 21
      Abstract: The distribution of drugs reimbursed by the NHS in Italy can be summarized in three forms: direct (DD), on behalf of (DPC) and affiliated. The following document presents the results of the discussion of a multidisciplinary experts’ panel, from different professional realities in the healthcare system, on alternative methods of drugs’ distribution. It was highlighted how regional autonomy has led to extremely innovative experiences but also to a lack of homogeneity regarding the access to pharmaceutical assistance across Italy. The main recommendations developed by the experts can be summarized as follows:
      To ensure decisions regarding prescription and classification, with respect to the healthcare delivery settings, with the consequent distribution model and purchasing processes, is AIFA’s responsibility.
      To evaluate the reclassification of drugs from class H to class A-PHT for drugs intended to be taken at patient’s home, in cases where close monitoring by specialistic structures is not necessary.
      To limit the inclusion of a drug in PHT to conditions of differential diagnostic complexity, need for recurrent patient’s referral to the healthcare facility, presence of AIFA monitoring register, settings of drugs’ administration (home hospitalization and home care).
      In the field of PHT drugs, AIFA should, with the support of a multidisciplinary technical table:
      Update the list periodically.
      Identify the drugs on the list for which DD is preferential, leaving the others in DPC.
      Evaluate the conditions to transfer some drugs to distribution under an agreement.
      PubDate: 2024-01-15
      DOI: 10.33393/grhta.2024.2619
      Issue No: Vol. 11, No. 1 (2024)
       
  • Italian healthcare resource consumption for patients on hemodialysis
           treated for chronic kidney disease-associated pruritus (CKD-aP)

    • Authors: Silvia Calabria, Manenti Lucio, Giulia Ronconi, Carlo Piccinni, Leonardo Dondi, Letizia Dondi, Antonella Pedrini, Immacolata Esposito, Alice Addesi, Filippo Aucella, Nello Martini
      Pages: 22 - 30
      Abstract: Background: Chronic kidney disease-associated pruritus (CKD-aP) affects patients on hemodialysis. This study identified hemodialysis patients presumably affected or not affected by CKD-aP and integrated healthcare costs, from the perspective of the Italian administrative healthcare data. Methods: Through cross-linkage of Italian administrative healthcare data collected between 2015 and 2017 (accrual period) in the database of Fondazione ReS (Ricerca e Salute), patients undergoing in-hospital/outpatient hemodialysis were selected. Cohorts with and without CKD-aP were created based on the presence/absence of CKD-aP-related treatment (according to common clinical practice and guidelines) supplies and assessed in terms of CKD-aP-related treatments and mean healthcare costs per capita paid by the Italian National Health Service (INHS). Results: Of 1,239 people on hemodialysis for ≥2 years, CKD-aP affected 218 patients. Patients with CKD-aP were older and with more comorbidities. During the follow-up year, on average, the INHS spent €37,065 per case, €31,286 per control and € 35,988 per non-CKD-aP subject. High-efficiency dialytic therapies performed to people on hemodialysis with CKD-aP largely weighed on the overall mean annual cost. Conclusions: This real-world study identified patients on chronic hemodialysis potentially treated for CKD-aP. Interestingly, high-efficiency dialysis seems the most frequent and expensive choice for the treatment of CKD-aP. The discovery of appropriate and effective treatments for this condition might offer cost offsets.
      PubDate: 2024-01-15
      DOI: 10.33393/grhta.2024.2696
      Issue No: Vol. 11, No. 1 (2024)
       
  • Clinical and economic burden of peristomal skin complications: Activity
           Based Costing analysis

    • Authors: Agostino Fortunato, Filippo Rumi, Massimo Zazzetta, Marco Della Valle, Vincenzo Pedace, Americo Cicchetti
      Pages: 31 - 37
      Abstract: Introduction: An ostomy is a procedure in which an opening is made in the abdominal wall to establish a communication between the intestinal or urinary system and the external environment. Peristomal skin complications pose a constant challenge for the majority of individuals with a stoma, as they represent the most common postoperative complication. The aim of this study was to develop an economic evaluation model for assessing the costs associated with peristomal skin complications. Methods: In order to identify these costs, a survey was conducted in collaboration with the Coloplast Ostomy Forum group with the aim of mapping and documenting the timelines and all activities in the management of these complications. The data obtained from the survey were subsequently analyzed using the Activity Based Costing methodology. Results: The results of this analysis clearly indicate that the expenditure for initial visits is higher compared to subsequent ones, and that severe peristomal skin complications impose a greater economic burden than less severe complications. Specifically, the average total cost for managing severe peristomal skin complications amounts to € 104.6. Conclusion: This kind of analysis could provide support to decision-makers in dealing with a more accurate estimate of costs related to healthcare processes, aiming to implement rates able to “cover” the overall cost of certain healthcare activities. Specifically, there is currently no specific rate aimed at defining the value associated with the care and management of this type of complication, so this study confirms that this is an economic challenge that the National Health Service must address.
      PubDate: 2024-01-23
      DOI: 10.33393/grhta.2024.2639
      Issue No: Vol. 11, No. 1 (2024)
       
  • Cost per NNT for upadacitinib in the treatment of patients with
           moderate-severe atopic dermatitis in Italy

    • Authors: Andrea Chiricozzi, Antonio Costanzo, Anna Levi, Federica Parretta, Roberto Ravasio
      Pages: 38 - 50
      Abstract: Background: Targeted systemic therapies, including abrocitinib, baricitinib, dupilumab, tralokinumab and upadacitinib, are new treatments for moderate to severe atopic dermatitis (AD). We evaluated the efficacy and the costs of these targeted systemic therapies in the treatment of adult patients with moderate to severe AD. Methods: The clinical efficacy was assessed considering the results of a previous network meta-analysis (NMA). The analysis involved five therapies approved in Italy for the treatment of moderate to severe AD: abrocitinib (ABR), baricitinib (BAR), dupilumab (DUP), tralokinumab (TRA) and upadacitinib (UPA). According to the NMA, the cost of the treatment was based on the number of administrations dispensed at 16 weeks and the clinical efficacy was measured by the number needed to treat (NNT) compared to placebo using the improvement ≥ 75% (EASI-75) or ≥ 90 (EASI-90) from baseline of the eczema area and severity index (EASI). Only the ex-factory price of the targeted systemic therapies was considered. The cost per NNT was adopted as a cost-effectiveness indicator. Results: At 16 weeks, the cost per NNT based on EASI-75 was lower for UPA 15 mg (€ 6,384.00) compared to BAR 4 mg (€ 11,619.73) and 2 mg (€ 14,524.66), ABR 100 mg (€ 16,265.22), DUP 300 mg (€ 16,115.04) and TRA 300 mg (€ 31,710.24). UPA 15 (€ 8,512.00) also showed the lower cost per NNT based on EASI-90 at 16 weeks compared to BAR 4 mg (€ 14,788.75) and 2 mg (€ 20,862.70), ABR 100 mg (€ 25,922.69), DUP 300 mg (€ 25,992.00) and TRA 300 mg (€ 41,067.36). Conclusions: The findings show that upadacitinib is the most cost-effective option (cost per NNT) for the treatment of moderate to severe atopic dermatitis.
      PubDate: 2024-02-16
      DOI: 10.33393/grhta.2024.2728
      Issue No: Vol. 11, No. 1 (2024)
       
 
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  Subjects -> HEALTH AND SAFETY (Total: 1464 journals)
    - CIVIL DEFENSE (22 journals)
    - DRUG ABUSE AND ALCOHOLISM (87 journals)
    - HEALTH AND SAFETY (686 journals)
    - HEALTH FACILITIES AND ADMINISTRATION (358 journals)
    - OCCUPATIONAL HEALTH AND SAFETY (112 journals)
    - PHYSICAL FITNESS AND HYGIENE (117 journals)
    - WOMEN'S HEALTH (82 journals)

CIVIL DEFENSE (22 journals)

Showing 1 - 18 of 18 Journals sorted alphabetically
Aggression and Violent Behavior     Hybrid Journal   (Followers: 348)
Canadian Journal of Remote Sensing     Full-text available via subscription   (Followers: 55)
Disaster Recovery Journal     Full-text available via subscription   (Followers: 4)
Disasters     Hybrid Journal   (Followers: 20)
Evolution, Medicine, and Public Health     Open Access   (Followers: 9)
Global & Regional Health Technology Assessment     Open Access   (Followers: 2)
International Journal of Critical Infrastructure Protection     Hybrid Journal   (Followers: 4)
International Journal of Emergency Management     Hybrid Journal   (Followers: 11)
International Journal of Emergency Services     Hybrid Journal   (Followers: 20)
International Journal of Forensic Engineering     Hybrid Journal   (Followers: 2)
International Journal of Intelligent Defence Support Systems     Hybrid Journal   (Followers: 4)
Journal of Applied Security Research     Hybrid Journal   (Followers: 3)
Journal of Health Care Law and Policy     Open Access   (Followers: 3)
Korean Journal of Defense Analysis     Hybrid Journal  
Prehospital and Disaster Medicine     Full-text available via subscription   (Followers: 8)
Risk, Hazards & Crisis in Public Policy     Hybrid Journal   (Followers: 5)
Strategic Analysis     Hybrid Journal   (Followers: 7)
Studies in Conflict & Terrorism     Hybrid Journal   (Followers: 364)
Similar Journals
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JournalTOCs
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Email: journaltocs@hw.ac.uk
Tel: +00 44 (0)131 4513762
 


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