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MEDICAL SCIENCES (2241 journals)            First | 1 2 3 4 5 6 7 8 | Last

Showing 601 - 800 of 3562 Journals sorted alphabetically
F&S Science : Official journal of the American Society for Reproductive Medicine     Open Access  
Facial Plastic Surgery & Aesthetic Medicine     Full-text available via subscription   (Followers: 3)
Facta Universitatis, Series : Medicine and Biology     Open Access  
Family Medicine and Community Health     Open Access   (Followers: 8)
Family Practice     Hybrid Journal   (Followers: 17)
Family Practice & Palliative Care     Open Access   (Followers: 5)
Family Practice Management     Full-text available via subscription   (Followers: 4)
Faridpur Medical College Journal     Open Access  
FEM : Revista de la Fundación Educación Médica     Open Access  
Finlay : Revista de Enfermedades no Transmisibles     Open Access  
Fisioterapia     Full-text available via subscription   (Followers: 2)
Fisioterapia & Saúde Funcional     Open Access  
Flugmedizin · Tropenmedizin · Reisemedizin - FTR     Hybrid Journal  
FMC - Formación Médica Continuada en Atención Primaria     Full-text available via subscription  
Folia Medica     Open Access  
Folia Medica Indonesiana     Open Access  
Folia Morphologica     Full-text available via subscription  
Folia Phoniatrica et Logopaedica     Full-text available via subscription   (Followers: 1)
Fontanus     Open Access  
Food Hydrocolloids for Health     Open Access  
Foodborne Pathogens and Disease     Hybrid Journal   (Followers: 11)
Foot & Ankle Specialist     Hybrid Journal   (Followers: 4)
Foot and Ankle Clinics     Full-text available via subscription   (Followers: 12)
Foot and Ankle Online Journal     Full-text available via subscription   (Followers: 6)
Forensic Science International : Mind and Law     Open Access   (Followers: 4)
Forum Medycyny Rodzinnej     Hybrid Journal  
Forum Zaburzeń Metabolicznych     Hybrid Journal  
Frontières     Full-text available via subscription   (Followers: 3)
Frontiers in Digital Health     Open Access   (Followers: 4)
Frontiers in Medical Technology     Open Access  
Frontiers in Medicine     Open Access   (Followers: 2)
Frontiers in Network Physiology     Open Access   (Followers: 2)
Frontiers in Neuroprosthetics     Open Access   (Followers: 6)
Frontiers in Synaptic Neuroscience     Open Access   (Followers: 2)
Frontiers in Tropical Diseases     Open Access  
Frontiers of Medical and Biological Engineering     Hybrid Journal  
Frontiers of Medicine     Hybrid Journal   (Followers: 2)
Fuss & Sprunggelenk     Hybrid Journal  
Future Medicinal Chemistry     Full-text available via subscription   (Followers: 5)
Future Prescriber     Hybrid Journal  
Future Science OA     Open Access  
Gaceta Médica Boliviana     Open Access  
Gaceta Médica Espirituana     Open Access  
Galen Medical Journal     Open Access  
Galician Medical Journal     Open Access   (Followers: 1)
Galle Medical Journal     Open Access  
Gefäßmedizin Scan     Hybrid Journal  
Gender and the Genome     Open Access   (Followers: 1)
Gene Expression     Full-text available via subscription   (Followers: 1)
General Reanimatology     Open Access  
Genes     Open Access   (Followers: 2)
Genome Instability & Disease     Hybrid Journal  
Geoforum     Hybrid Journal   (Followers: 25)
Gestão e Desenvolvimento     Open Access  
Ghana Medical Journal     Open Access   (Followers: 1)
GigaScience     Open Access   (Followers: 4)
Gimbernat : Revista d’Història de la Medicina i de les Ciències de la Salut     Open Access  
Glia     Hybrid Journal   (Followers: 5)
Global Advances in Health and Medicine     Open Access  
Global Bioethics     Open Access   (Followers: 5)
Global Health : Science and Practice     Open Access   (Followers: 7)
Global Health Journal     Open Access   (Followers: 2)
Global Journal of Integrated Chinese Medicine and Western Medicine     Open Access  
Global Journal of Cancer Therapy     Open Access  
Global Journal of Fertility and Research     Open Access  
Global Journal of Health Science     Open Access   (Followers: 5)
Global Journal of Infectious Diseases and Clinical Research     Open Access  
Global Journal of Medical and Clinical Case Reports     Open Access  
Global Journal of Obesity, Diabetes and Metabolic Syndrome     Open Access   (Followers: 1)
Global Journal of Perioperative Medicine     Open Access  
Global Journal of Rare Diseases     Open Access  
Global Medical & Health Communication     Open Access   (Followers: 1)
Global Reproductive Health     Open Access  
Grande Medical Journal     Open Access  
Growth Factors     Hybrid Journal   (Followers: 2)
GSTF Journal of Advances in Medical Research     Open Access  
Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi     Open Access  
Hamdan Medical Journal     Open Access  
Hämostaseologie     Hybrid Journal   (Followers: 5)
Hämostaseologie     Open Access  
Hand     Hybrid Journal   (Followers: 4)
Hand Clinics     Full-text available via subscription   (Followers: 6)
Hand Therapy     Hybrid Journal   (Followers: 11)
Hard Tissue     Open Access  
Head & Face Medicine     Open Access   (Followers: 1)
Head and Neck Cancer Research     Open Access  
Head and Neck Tumors     Open Access  
Health Information : Jurnal Penelitian     Open Access  
Health Matrix : The Journal of Law-Medicine     Open Access  
Health Notions     Open Access  
Health Science Journal of Indonesia     Open Access  
Health Science Reports     Open Access   (Followers: 1)
Health Sciences and Disease     Open Access   (Followers: 1)
Health Sciences Review     Open Access  
Health Security     Hybrid Journal   (Followers: 1)
Healthcare Technology Letters     Open Access  
Hearing, Balance and Communication     Hybrid Journal   (Followers: 6)
Hearts     Open Access   (Followers: 1)
HEC Forum     Hybrid Journal   (Followers: 1)
Heighpubs Otolaryngology and Rhinology     Open Access  
Heilberufe     Hybrid Journal  
HeilberufeSCIENCE     Hybrid Journal  
Heilpflanzen     Hybrid Journal   (Followers: 3)
Helicobacter     Hybrid Journal  
HemaSphere     Open Access   (Followers: 2)
Hemoglobin     Hybrid Journal  
Hepatology, Medicine and Policy     Open Access  
HERALD of North-Western State Medical University named after I.I. Mechnikov     Open Access  
Herald of the Russian Academy of Sciences     Full-text available via subscription  
Herzschrittmachertherapie + Elektrophysiologie     Hybrid Journal  
Highland Medical Research Journal     Full-text available via subscription  
Hipertensión y Riesgo Vascular     Full-text available via subscription  
HIV Australia     Full-text available via subscription   (Followers: 3)
Homeopathy     Hybrid Journal   (Followers: 1)
Homoeopathic Links     Hybrid Journal  
Hong Kong Physiotherapy Journal     Open Access   (Followers: 14)
Horizonte Medico     Open Access  
Hormones : International Journal of Endocrinology and Metabolism     Hybrid Journal  
Hospital a Domicilio     Open Access  
Hospital Practices and Research     Open Access  
Hospital Topics     Hybrid Journal   (Followers: 1)
Hua Hin Sook Jai Klai Kangwon Journal     Open Access  
Huisarts en wetenschap     Hybrid Journal   (Followers: 4)
Human & Veterinary Medicine - International Journal of the Bioflux Society     Open Access   (Followers: 4)
Human Factors in Healthcare     Open Access  
Human Fertility     Hybrid Journal   (Followers: 4)
Humanidades Médicas     Open Access  
I.P. Pavlov Russian Medical Biological Herald     Open Access  
Iatreia     Open Access  
Ibnosina Journal of Medicine and Biomedical Sciences     Open Access  
IDCases     Open Access  
IEEE Journal of Biomedical and Health Informatics     Hybrid Journal   (Followers: 14)
IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology     Hybrid Journal  
IEEE Journal of Translational Engineering in Health and Medicine     Open Access   (Followers: 5)
IEEE Open Journal of Engineering in Medicine and Biology     Open Access   (Followers: 1)
IEEE Transactions on Medical Robotics and Bionics     Hybrid Journal   (Followers: 3)
IEEE/ACM Transactions on Computational Biology and Bioinformatics     Hybrid Journal   (Followers: 18)
IJID Regions     Open Access   (Followers: 1)
IJS Global Health     Open Access  
IJU Case Reports     Open Access  
iLiver     Open Access   (Followers: 2)
Im OP     Hybrid Journal  
Image Analysis & Stereology     Open Access   (Followers: 1)
IMAGING     Full-text available via subscription   (Followers: 1)
Imaging in Medicine     Open Access  
Imaging Journal of Clinical and Medical Sciences     Open Access   (Followers: 1)
Imam Journal of Applied Sciences     Open Access  
Indian Journal of Ayurveda and lntegrative Medicine Klue     Open Access   (Followers: 3)
Indian Journal of Burns     Open Access   (Followers: 2)
Indian Journal of Clinical Medicine     Open Access  
Indian Journal of Community and Family Medicine     Open Access   (Followers: 2)
Indian Journal of Community Medicine     Open Access   (Followers: 1)
Indian Journal of Health Sciences and Biomedical Research KLEU     Open Access   (Followers: 2)
Indian Journal of Medical Microbiology     Open Access   (Followers: 1)
Indian Journal of Medical Research     Open Access   (Followers: 3)
Indian Journal of Medical Sciences     Open Access   (Followers: 2)
Indian Journal of Medical Specialities     Hybrid Journal  
Indian Journal of Otology     Open Access   (Followers: 1)
Indian Journal of Public Health     Open Access   (Followers: 1)
Indian Journal of Transplantation     Open Access  
Indian Spine Journal     Open Access  
Indo-Pacific Journal of Phenomenology     Open Access   (Followers: 1)
Indonesia Journal of Biomedical Science     Open Access   (Followers: 1)
Indonesian Biomedical Journal     Open Access  
Indonesian Journal for Health Sciences     Open Access   (Followers: 1)
Indonesian Journal of Medicine     Open Access  
Indonesian Journal of Tropical and Infectious Disease     Open Access  
Infant Observation: International Journal of Infant Observation and Its Applications     Hybrid Journal   (Followers: 1)
Inflammation     Hybrid Journal   (Followers: 3)
Inflammation Research     Hybrid Journal   (Followers: 4)
Info Diabetologie     Full-text available via subscription   (Followers: 1)
Infodir : Revista de Información científica para la Dirección en Salud     Open Access  
Informatics in Medicine Unlocked     Open Access  
Injury Prevention     Hybrid Journal   (Followers: 6)
InnovAiT     Hybrid Journal   (Followers: 1)
Innovare Journal of Health Science     Open Access  
Innovare Journal of Medical Science     Open Access  
Innovation in Aging     Open Access   (Followers: 1)
Inside Precision Medicine     Full-text available via subscription   (Followers: 4)
Insights in Biology and Medicine     Open Access  
Integrative and Complementary Therapies     Full-text available via subscription   (Followers: 4)
Integrative Medicine Insights     Open Access   (Followers: 1)
Integrative Medicine International     Open Access   (Followers: 1)
Integrative Medicine Research     Open Access   (Followers: 3)
Intellectual Disability Australasia     Full-text available via subscription   (Followers: 12)
Intelligence-Based Medicine     Open Access  
Intelligent Medicine     Open Access   (Followers: 1)
intensiv     Hybrid Journal   (Followers: 1)
interactive Journal of Medical Research     Open Access  
Interdisciplinary Perspectives on Infectious Diseases     Open Access  
Interdisciplinary Sciences : Computational Life Sciences     Hybrid Journal   (Followers: 2)
Internal Medicine     Open Access   (Followers: 1)
International Biomechanics     Open Access   (Followers: 1)
International Health     Hybrid Journal   (Followers: 5)
International Health Trends and Perspectives     Open Access  
International Journal for Numerical Methods in Biomedical Engineering     Hybrid Journal   (Followers: 2)
International Journal for Vitamin and Nutrition Research     Hybrid Journal   (Followers: 10)
International Journal of Academic Medicine     Open Access   (Followers: 1)
International Journal of Advance in Medical Science     Open Access  
International Journal of Advanced Medical and Health Research     Open Access  

  First | 1 2 3 4 5 6 7 8 | Last

Similar Journals
Journal Cover
Global Journal of Medical and Clinical Case Reports
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2455-5282
Published by Peertechz Homepage  [75 journals]
  • Glimepiride induced Syndrome of Inappropriate Antidiuretic Hormone
           Secretion (SIADH): A case report

    • Abstract: The Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is an important cause of hyponatremia in hospitalized patients and can be caused by a variety of drugs. SIADH is a recognized side effect of 1st generation sulfonylurea (Chlorpropamide) due to its effect on vasopressin secretion. Here we described a 55-year-old woman with uncontrolled type 2 diabetes on glimepiride with SIADH presenting with anorexia, asthenia, and altered mental status. After the withdrawal of glimepiride, these symptoms were improved and sodium level returned to a normal value which demand monitoring of serum sodium level during treatment with glimepiride.
      PubDate: 30 Apr, 2022
       
  • Antimicrobial resistance: An unrelenting enemy

    • Abstract: Antimicrobial Resistance (AMR) poses an increasing threat to global public health and is projected to be one of the greatest challenges of healthcare in the future as the costs of healthcare, morbidity, and mortality will increase. AMR is likely to complicate many routine procedures such as elective surgery in the future. Together, healthcare professionals need to be aware of the significance antimicrobial resistance poses and make changes needed to mitigate the danger as a result of one of the most important developments in medicine.
      PubDate: 24 Jan, 2022
       
  • The role of interleukin-17 in spondyloarthropathies and systemic lupus
           erythematosus: Two clinical cases in real

    • Abstract: Spondyloarthropathies are known to affect the interleukin (IL)-17 activation pathway as a basis of their pathology, as is apparent from the literature. Recent studies established the vital role of IL-17 in the treatment of Systemic Lupus Erythematosus (SLE). This article aims to demonstrate the efficacy and safety of IL-17 in the treatment of both spondyloarthropathies and SLE by presenting two cases.The first case concerns a 30-year-old woman who was initially diagnosed with SLE. In the course of the disease, she developed spondyloarthritis and genital psoriasis. She was initially medicated with secukinumab but maintained severe genital psoriasis, the reason it was changed to ixekizumab with great improvement.The second case refers to a 40-year-old woman who previously had spondyloarthropathy with D12 enthesitis and sacroiliitis. Initial treatment with adalimumab led to a lupus-like syndrome, with persistent high systemic inflammatory response syndrome and extreme fatigue. Because of the recrudescence of axial complaints, secukinumab was started and the patient evolved with a global clinical response.Thus, the authors present two cases of spondyloarthropathy and SLE that document the efficacy and safety of IL- 17 blockers, which can lead to the incorporation of these agents in the treatment of SLE.
      PubDate: 19 Jan, 2022
       
  • Cloverleaf plasma cell nuclei in multiple myeloma

    • Abstract: A 65-year-old man was diagnosed with multiple myeloma (IgG-Lambda) and was treated with high-dose dexamethasone as induction therapy followed by thalidomide-based regimens. About 18 months after the initial diagnosis, the patient presented a first relapse which was treated with the LCD protocol (Lenalidomide, Cyclophosphamide, Dexamethasone).
      PubDate: 18 Mar, 2022
       
  • Gastrointestinal stromal tumor revealed by hemorrhagic shock

    • Abstract: Gastrointestinal Stromal Tumors (GISTs) are rare tumors of the digestive tract. The small intestine is the second most frequent localization of GIST after the stomach. We report a case of the ileal stromal tumor. The patient was admitted with a picture of hemorrhagic shock due to massive rectal bleeding. The fiberscope performed after stabilization was not objectified at the origin of the document while the CT scan objectified a mass of tissue density at the level of the right iliac fossa. Given the increasing evolution with the recurrence of patients to a target of a laparotomy for diagnostic and therapeutic purposes objectifying the tumor of the right iliac fossa at the expense of the ileum. The surgical procedure consisted of a major segmental resection of the tumor with ileo-ileal anastomosis. The anatomopathological study confirmed the diagnosis of the stromal tumor with good evolution. Through a general review of the literature, we have described the various clinical, para-clinical, anatomopathological, prognostic, and current therapeutic aspects specific to these tumors.
      PubDate: 09 Mar, 2022
       
  • Pneumomediastinum following dental extraction – a case report in a
           tertiary hospital

    • Abstract: Pneumomediastinum is a rare complication described following dental extraction, especially of the third molar. 212 case reports were described in the English literature since 1960. We describe a case report of a 19-year-old girl who presented to the emergency department with subcutaneous emphysema. Investigations showed the presence of pneumomediastinum. The patient was admitted for surveillance with no antibiotic therapy given due to the improvement seen the following day.
      PubDate: 07 May, 2022
       
  • Post traumatic facial artery pseudoaneurysm-A case report

    • Abstract: Facial artery a branch of external carotid artery rarely develops an aneurysm due to its superficial location and small size that mostly leads to complete dissection rather than laceration of the vessel. Pseudo-aneurysms develop in the superficial temporal arteries in this region. Rupture of this aneurysm can lead to extravasation of blood within the adjacent soft tissues resulting in hemorrhage in some cases. Only a few cases of facial artery aneurysms have been reported in publications. We are therefore discussing here a case of left facial artery pseudoaneurysm secondary to trauma and its radiological imaging findings on CT angiogram.
      PubDate: 04 Jan, 2022
       
  • Activating dormant strongyloidiasis secondary to COVID-19 treatment

    • Abstract: The SARS-CoV-2 pandemic has grown into a major global concern with huge efforts to combat the spread. Exaggerated inflammatory response plays a major role in which was the rationale to use corticosteroids to treat patients. However, multiple studies showed an association between opportunistic and bacterial infections with corticosteroid therapy. We report a case of a 76 year old patient diagnosed with COVID-19 treated with 10 days Dexamethasone and Remdesivir who presented with abdominal symptoms with eosinophilia. Biopsy and stool studies revealed Strongyloides stercoralis larvae. The patient was treated with 2 doses of Ivermectin with significant clinical resolution. Clinician should have high clinical suspicion for Strongloydiasis in patients who have lived or visited endemic areas and for patients with unexplained eosinophilia. Prompt treatment with Ivermectin is crucial for confirmed cases and high risk cases where obtaining a diagnosis is unfeasible.
      PubDate: 01 Feb, 2022
       
  • Perrotta Integrative Clinical Interview (PICI-1): A new revision proposal
           for PICI-1TA. Two single cases

    • Abstract: Purpose: This research aims to reinforce the credibility of the PICI-1 psychodiagnostic instrument by making some corrections that are immediately evident in several clinical cases. Among all, the proposed case represents the clearest and most effective example.Methods: Clinical interview and administration of the MMPI-II, PICI-1 and PSM-1.Results: On the basis of specific clinical observations, evident in the proposed cases, the following corrections to the basic PICI-1 model have been suggested: 1) at the diagnostic level: the diagnosis must take into account the first two highest levels of dysfunctional traits, considering the next three lower levels as elements of psychotherapeutic interest. In the hypothesis of dysfunctional hyperactivation, the diagnosis should be re-evaluated at the end of the psychotherapeutic pathway; 2) on the unitary diagnosis: the diagnosis takes into account, in its final formulation, the primary disorder (P, main diagnosis), co-primary disorders (M, mixed diagnosis), comorbidities (C), secondary disorders (S), and tertiary traits (T); 3) on the symptomatic persistence of symptoms and on the plasticity of the personality: mindfulness can aid change, as long as it is real, concrete, and current, and the complained of dysfunctional traits have not been present for a long time (more than 1 year, anyway); 4) on absorptions: anxiety disorder absorbs somatic disorder, phobic disorder, and manic disorder, the latter becoming specific traits of anxiety (main) disorder; psychotic disorders absorb all other neurotic disorders.Conclusions: The results obtained from the two proposed clinical cases suggest the following modifications to the model. These corrections actually facilitate the psychological course and the diagnostic interpretation of the patients, who were able to alleviate their suffering to an acceptable level of tension, without pharmacological support.
      PubDate: 30 Apr, 2021
       
  • An unusual case of foreign body aspiration

    • Abstract: Tracheo-Oesophageal Puncture (TEP) with voice prosthesis insertion is considered as a gold standard among various voice rehabilitation procedures in laryngectomized patients. It is easily reversible with a high success rate, and the speech, which closely resembles laryngeal speech, develops faster than esophageal speech. However the prosthesis has to be cleaned regularly to ensure proper function as well as longevity of the voice prosthesis valve system. There are not many incidents of the voice prosthesis cleaning brush reported, as the cleaning brush is made to be durable and able to withstand repetitive usage. Hereby we describe an unusual case of a laryngectomized patient who had aspirated a broken tip of a cleaning brush while cleaning his voice prosthesis. The delay in removal of the aspirated foreign body due to technical difficulty had led to lung collapse subjecting the patient to partial lobectomy. We would like to highlight several aspects in this case report, firstly patients should be counselled regarding the proper techniques to clean the voice prosthesis and they should be vigilant during the cleaning process to prevent aspiration in case of accidental broken of cleaning brush. Secondly the incident should be reported to the manufacturer so that the durability of the cleaning brush is reviewed and improvised. Lastly, prompt management of foreign body aspiration should be implied to prevent complications.
      PubDate: 28 Jul, 2021
       
  • Anatomical evaluation of the craniometric points and dimensions among
           adult’s populations of the South-Eastern Nigerians and its implication
           for intracranial surgical procedures

    • Abstract: Background: The understanding of Craniometry with its associated craniometric points and dimensions have found immense applicable relevance in anthropology and neuroscience, ranging from growth determination, estimation of cranial deformities, personal biological profile identification and facial reconstructive surgeries, analysis of evolution of the human species in archeology as well as age variations. Objective: The aim of this study was to evaluate the craniometric dimensions among adults’ subjects in Eastern Nigerian State. Methods: Research data was collected from Computed Tomography scans in the Radiological Department of Federal Medical Centre, Umuahia, Nigeria with strict adherence to inclusive and exclusive factors. A total number of 150 human CT scans were used in the findings. Craniometric parameters were calculated - derived from the two and three coordinate points for linear and angular measurements respectively. Results: Results revealed that age group 36-45 had the lowest cranial parameters and age group 56-65 had the highest cranial parameters. Conclusion: It was concluded that cranial parameters does not increase as age increases throughout life. The study findings will be useful to the anatomists, anthropologists and neuroscientists.
      PubDate: 27 Oct, 2021
       
  • Astra zeneca Covid vaccination conversion reaction

    • Abstract: Introduction: This paper reports a patient who presented with hemiparesis and hemisensory hypo-aesthesia following the AstraZeneca vaccine. Formal neurological assessment diagnosed a conversion reaction.Case report: A 60 year old lady presented with left sided weakness and hypo-aesthesia after her first dose of the AstraZeneca vaccine. She became unable to walk, had blurred vision and a bitter taste. There was no similar previous history. Depression and anxiety were diagnosed in 2007.Physical examination revealed positive Hoover’s signs, without features to suggest either upper or lower motor neurone deficit. She had non-anatomic loss of sensation, across her torso, plus non-anatomical demarcation of decreased trigeminal sensation. She was advised that her most likely diagnosis was that of a non-organic conversion reaction but she did undergo cerebral imaging together with a psychiatric assessment, prior to discharge. Discussion: The AstraZeneca Covid-19 vaccine has received significant publicity regarding potential for clotting. This case highlights the consequences of this concern. Physical examination suggested a non-organic complaint, allowing the provisional diagnosis of a conversion reaction. Advising the patient allowed her to accept that, when all the tests came back normal, it did not reflect lack of knowledge to make a correct diagnosis. The correct procedure is to make a provisional diagnosis (namely conversion reaction) and to exclude differential diagnoses, such as clotting. It is believed that this represents the first reported case of an AstraZeneca Covid vaccination conversion reaction but it is highly unlikely that it will be the last one to be encountered.
      PubDate: 27 Jul, 2021
       
  • The role of mobile handheld lung ultrasound in the diagnosis and
           monitoring of C0VID-19 atypical pneumonia

    • Abstract: Background: Our aim is to present the importance of mobile Handheld Lung Ultrasound (HLUS) in COVID-19 patients at the bedside, which is a pre-screening tool with high diagnostic value that can provide triage of symptomatic patients at home (pre-hospital), emergency services, Intensive Care Units (ICU). In this context, the current role and importance of HLUS at the bedside in COVID-19 pneumonia has been summarized.Method: We searched pubmed with key words; COVID-19 pneumonia, Lung Ultrasound (LUS), handheld ultrasound and reached 2428 articles with full texts. All abstracts were searched and 470 systematic review and meta-analysis determined. Only 10 articles were directly related to COVID-19 pneumonia and HLUS. These articles were interpreted to determine the role of HLUS at the bedside in COVID-19 pneumonia.Results: Although not specific for COVID-19, Ultrasonography (US) findings of peripheral interstitial viral pneumonias due to COVID-19 lung involvement are very characteristic. The use of HLUS in COVID-19 atypical pneumonia is of critical importance due to its high diagnostic value in diagnosis and follow-up. It was shown that the sensitivity and specificity of bedside LUS in the diagnosis of atypical pneumonia were high enough to include in radiologic algorithm.Conclusions: Handheld pocket-sized US devices are cheap, easy to handle and equivalent to standard scanners for non-invasive assessment of severity and dynamic observation of lung lesions in COVID-19 patients with pneumonia. So it has become of great importance to make a useful and simple radiological algorithmic approach that includes bedside HLUS in the diagnosis and follow-up of COVID-19 pneumonia patients.
      PubDate: 27 Jan, 2021
       
  • Efficacy of cognitive restructuring technique on adjustment of social
           isolates in a sample of nigerian secondary school adolescences

    • Abstract: Objective: Of the study is to investigate the efficacy of Cognitive Restructuring Technique on Adjustment of Social Isolates in a sample of Nigeria Secondary School Adolescents. Methods: Pre-test post-test randomized control trial experimental design was adopted by the researchers for the study (60). Secondary school adolescents who were drawn through proportionate stratified randomly sampling technique constituted the sample for the study. The secondary school adolescents were randomly assigned to experimental (32) and (28) groups. Social Isolates Assessment scale for Adolescents (SIASA) and Adjustment Scale of Social Isolates (ASSI) were used for data collection. SIASA and ASSI were properly validated by experts in the test development and the internal consistency reliability indices of the items estimated as 0.82 and 0.86 respectively using Cronbach Alpha method. Before the commencement of the testing and treatment package, the researchers assured the participants of confidentiality of interactions and personal information as they work together in self-disclosure. Thereafter, pre-treatment assessment (pre-test) was conducted using the SIASA and ASSI in order to collect baseline data (Time 1). After that, the experimental group was exposed to 90 minutes of the Cognitive Restructuring Technique (CRT) program twice a week for a period of 6-weeks. The treatment took place between September and November 2019. Post-test (Time 2) assessment was conducted 1 week after the last treatment session. Besides, a follow-up assessment was conducted after two months of the treatment (Time 3). Data collected were analyzed using repeated measures analysis of variance. Results: The findings of the study revealed that the efficacy of cognitive restructuring technique on the adjustment of social isolates adolescents was significant at post-test and follow-up measures. One of the contributions of the findings is that if secondary school adolescents are not properly counseled, their social isolate behavior will continue to increase. Conclusion: The contribution among others is that Federal Government or relevant education authorities should provide enough guidance counselors in the various institutions of learning who will assist in the counseling of adolescents in the dangers of social isolate behaviour using CRT.
      PubDate: 27 Feb, 2021
       
  • Anthracycline-based combination chemotherapy (Doxorubicin and Dacarbazine)
           for the desmoid tumor in a neoadjuvant setting. Report of a case

    • Abstract: We report a case of a 41-years-old female with a sporadic abdominal wall desmoid tumor. After a period of 12-months observation, chemotherapy was given with Doxorubicin and Dacarbazine to facilitate minimal surgery. The patient received 4 cycles of chemotherapy. Treatment was well tolerated and resulted in a significant reduction of the tumor size from 48mm to 25mm, 48% reduction. The tumor was surgically resected, and the histopathology from the resected specimen revealed a partial pathological response. At 6 months post-surgery, there is no recurrence or surgical complications.
      PubDate: 26 Apr, 2021
       
  • Atypical presentation of a fish bone foreign body: A case report and
           review of the literature

    • Abstract: Introduction: Fish bone Foreign Body (FFB) accidental ingestion is a most common presenting complaint for patients attending the emergency department. It is more frequently lodged within the oropharynx and the oesophagus. However, fish bone impacting in the respiratory system is extremely rare; accounting for 14% of reported cases, with approximately few cases reported in the literature involved the lower airway. Patient concern: A 27- year-old man presented clinically as a case of chest infection with a 5-day history of palpitation, right pleuritic chest pain and shortness of breath. Diagnosis: We report a case of atypical presentation of FFB ingestion. Although patients with foreign bodies’ ingestion sometimes presented with cough, there are a wide spectrum of clinical symptoms, especially those with lower airway FFB; where imaging findings are not usually spotted in the emergency department to point to the diagnosis. Intervention: Swab for COVID-19 was negative and the initial chest X-ray showed poor inspiratory effort and no air space opacity. Although CT pulmonary angiography for pulmonary embolism was negative, an incidental finding suggestive of foreign body was reported in the right lower lung region.Outcomes: The foreign body was distal within the lung parenchyma; therefore, there was no need for urgent surgical intervention and there should be a 1-month outpatient clinic follow-up and patient was discharged on antibiotic.Conclusion: Although fish bone ingestion is a common food related foreign body ingestion, cases can often present a diagnostic dilemma and can be easily misdiagnosed or mistaken for other diagnoses. Therefore, vigilant and thorough history taking, and the consideration of a FFB in the differential diagnosis is essential.
      PubDate: 23 Apr, 2021
       
  • Atypical Pyoderma Gangrenosum with Ulcerative Colitis treated successfully
           with prednisolone and mesalazine: A case report

    • Abstract: Introduction: Pyoderma Gangrenosum (PG) manifests as recurrent deep ulceration of the skin and PG is often associated with a variety of systemic diseases, such as Inflammatory Bowel Diseases (IBD), inflammatory arthropathies, hematologic malignancies and hepatitis. There has been neither laboratory finding nor histological feature diagnostic of PG, and diagnosis of PG is mainly made based on the exclusion criteria.Patient and methods: A male patient 21 years old, complained of rectal bleeding of 3 weeks duration. He presented with a large, painful and rapidly progressive cutaneous ulcer in the right flank. Laboratory and microbiological investigations, colonoscopic biopsy and a skin biopsy from the ulcer were performed. Results: An atypical presentation of PG with Ulcerative Colitis (UC) was diagnosed. The PG rapidly resolved after starting treatment with prednisolone and mesalazine and the ulcer healed with scar. After successful treatment the patient suddenly stopped all his treatment and he came back again with rectal bleeding and a rounded, painful and rapidly progressive cutaneous ulcer in each cheek. One month after starting prednisolone and mesalazine treatment, complete healing of both ulcers has occurred.Conclusion: A rare atypical presentation of PG with risk of misdiagnosis and the rapid healing of PG with combination of prednisolone and mesalazine therapy were concluded.
      PubDate: 22 Jul, 2021
       
  • Picking the right surgeon: Quantitative approach

    • Abstract: There is an abundance of useful verbal information and recommendations on how to make the best choice when referring a patient for surgery or when seeking the right surgeon for your own operation.
      PubDate: 22 Dec, 2021
       
  • The glycocalyx may play an important role in Preventing Sepsis Campaign in
           China (PSCC)

    • Abstract: Sepsis is a common clinical emergency and critical illness, whose prevention and treatment are mainly to protect organ functions. Glycocalyx is a polysaccharide-protein composite structure on the surface of endothelial cells, which has the functions of protecting cell barriers and maintaining organ perfusion. It may protect the organ function, and prevent the infected patients from progressing to sepsis by monitoring of glycocalyx in the serum. This article mainly summarized the cause of PSCC and the possible role of glycocalyx in PSCC to provide reference for clinical intervening.
      PubDate: 22 Apr, 2021
       
  • Case report: Acute Kidney Injury, Liver impairment, Severe Anemia in a
           child with Malaria and Hyperparasitaemia

    • Abstract: Severe Malaria is a medical emergency mainly because of its rapid progression to complications and death if not promptly and adequately treated. In 2018 WHO put the incidence of P. falciparum Malaria in the African region to be around 99.7%.We present a case where a boy who presented with high grade fever, prostration, and jaundice. On investigation he was found to have parasitemia of 35%, met multiple criteria for Severe Malaria namely: Hyper-parasitemia, Thrombocytopenia, Anemia and Metabolic acidosis. The child was treated with I.V. Artesunate and I.V. Antibiotics, developed AKI (Acute kidney injury) during the hospital stay necessitating multiple dialysis sessions before making a complete recovery. This is a rare case in several aspects as discussed below.
      PubDate: 19 Jan, 2021
       
  • Eruptive xanthomas secondary to severe hypertriglyceridemia

    • Abstract: Xanthomas are benign cutaneous manifestations of extracellular lipid accumulation. Eruptive xanthoma is characterized by the acute, widespread presentation of a papular rash and usually involves the back, buttocks, and extremities. Eruptive xanthoma is associated with hyperlipidemia, hypertriglyceridemia, and an increased long-term risk of atherosclerotic cardiovascular disease. We present a case of eruptive xanthoma accompanied by severe hypertriglyceridemia (10,164 mg/dL) in which the course of the disease was reversed following implementation of lipid-lowering pharmacotherapy.
      PubDate: 18 Oct, 2021
       
  • Association of ulcerative colitis and IgA nephropathy: A case report

    • Abstract: The extradigestive manifestations of chronic inflammatory bowel disease most often affect the articulations, skin, eyes, liver and bile ducts. Renal involvement is rare, and manifests as kidney stones, glomerulonephritis, tubulointerstitial nephritis, and secondary amyloidosis. In this context of chronic inflammatory bowel disease, in particular ulcerative colitis, renal involvement is very often secondary to nephrotoxicity of the basic treatment of digestive pathology, and very rarely an authentic extradigestive manifestation of intestinal disease. We report a case of IgA nephropathy as an extra-digestive manifestation of ulcerative colitis.The objective of this study is not to neglect the IgA nephtopathy as an extradigestive manifestation of IBD which, even though rare, remains a condition to be looked for by clinicians during the follow-up of IBD.
      PubDate: 17 Sep, 2021
       
  • Subvesical duct and hepaticocholecystic duct in one patient

    • Abstract: Subvesical bile ducts (formerly known as “Ducts of Luschka”) are a rare entity associated with bile leaks due to their proximity to the gallbladder bed.Failure to recognise their presence could lead to life-threatening complications to the patient in the form of an abdominal collection, biliary peritonitis and sepsis.We describe a patient with two abnormal ducts found in the gallbladder fossa which were managed surgically.
      PubDate: 16 Mar, 2021
       
  • Posterior aortopexy is the option

    • Abstract: Tracheomalacia is the abnormal collapse and flaccidity of the supporting tracheal cartilage, leading to a reduction in the caliber of the anterior-posterior airway. Tracheomalacia is common after cardiac compression or tracheoesophageal fistula. In the severe type, tracheomalacia may lead to significant morbidity, especially if encountered at a younger age or in a critical area, such as the distal part of the trachea. We report two cases that did not improve after initial cardiac surgery with persistent airway narrowing of more than 80%, requiring prolonged ventilatory support. Both cases were difficult to manage but eventually showed a significant improvement after posterior aortopexy, which helped to wean them off the ventilator and produced marked clinical and radiological improvement. Both cases had residual malacia that was clinically presented as persistent audible wheezing and recurrent chest exacerbation. The diagnostic and therapeutic options for both cases are discussed.
      PubDate: 13 Mar, 2021
       
  • Long term outcomes of Hospital-Identified Clostridium Difficile Infection
           (HICDI): A retrospective cohort analysis of adult patients in a teaching
           hospital

    • Abstract: Objectives: To study long term outcomes of HICDI. Design, settings and participants: Retrospective cohort study of adult patients diagnosed with HICDI during their admission to a tertiary teaching hospital between January 1st 2012 and December 31st 2016. Main outcomes: Primary aim was to study two-year mortality outcome and it’s predictors in HICDI patients. Secondary outcomes were to identify characteristics of HICDI and predictors of time to resolution of infection. Results: A total of 819 adult HICDI episodes were identified. 544 episodes occurring in 466 patients were included in final analysis. Single CDI episodes occurred in 409 patients, 45 patients had 2 episodes and 12 patients had greater than 2 episodes.Two-year all-cause mortality was 33% (152/409) in single CDI episodes and 61.4% (35/57) for those with more than one CDI episode. Of the 466 patients, the in-hospital all-cause mortality directly attributed to CDI was 14 patients (3%). Risk factors predicting long-term mortality were, chemotherapy (AHR(adjusted hazard ratio)2.7; 95% CI 1.90-3.81;p=0.01), low albumin(AHR 2.44; 95% CI 1.83-3.47; p=0.01), ICU admission(AHR 2.09, 95% CI 1.44-3.03; p=0.01) high WBC count (AHR 1.78,CI 1.28-2.30; p=0.01), multiple CDIs (AHR 1.24,95% CI 1.09-1.39; p=0.01) and age (AHR:1.04;95%CI:1.03–1.05;p=0.01).Most common type of HICDI was Hospital –Acquired CDI (HA-CDI) (55.8 %; n=260). Antibiotic usage before developing CDI significantly delayed the time to resolution of infection (AIRR: 1.35; 95% CI 1.06-1.71; p=0.01). In 1/3rd (n=180) of HICDI episodes, patients were discharged before resolution of diarrhoea. Majority of HICDI episodes (n=371) were treated with metronidazole.Conclusion: HICDI was associated with significant long term mortality and morbidity. Mortality increased with more than one CDI infection. Antibiotic usage before developing CDI significantly delayed the time to resolution of infection.
      PubDate: 12 Feb, 2021
       
  • A comparative study to analyze the effect of planter fascia stretch and
           heel pad with moist heat in the patients of planterfascitis

    • Abstract: Background: This study investigated the effect of planter fascia stretch and heel pad with moist heat in the patients of planterfascitis among subjects aged 20-40. Planter fascia is a thickened fibrous sheet of connective tissue which begins from medial tubercle on undersurface of calcaneus and fans out joining to the metatarsophalangeal joints plates to form longitudinal foot arch. Manual active stretching or passive stretching of planter fascia and Achilles tendon are effective treatment option for patient with planter fasciitis. Aims and objectives: objectives of this study were to see the effect of planter fascia stretch and heel pad with moist heat in the patients of planterfascitis. Material and methodology: This study was quasi experimental study. It took samples by convenient method from 80 subjects among Faisalabad private hospitals community. The study was completed in the duration of 3 months. Data was conducted through convenient sampling from Faisalabad private hospitals. This study explored the effect of planter fascia stretch and heel pad with moist heat on subjects aging 20-40 years old. Subjects were allocated to group A (n=40) and group B (n=40). Group A received treatment as planter fascia stretch and group B received treatment as heel pad with moist heat. Follow up were taken after 4 weeks in 3 month duration study. Results: Statistical Analysis Data were analyzed using SPSS version 23.0. Intragroup comparison of differences between pre and post intervention scores of FFI and FADI was analyzed using independent T Test. The results were considered statistically significant if p values were less than 0.05). No statistically significant difference was observed in pre intervention score between the groups on FADI (p = 0.211) and FFI (p = 0.365), but, statistically significant difference was observed between all the groups on post intervention score with respect to FADI (p=0.000) and FFI (p=.001) as analyzed by independent t test. Conclusion: After applying the entire treatments and measuring pre and post value it conducted that planter fascia stretch has more significant effect on planterfascitis than heel pad with moist heat.
      PubDate: 12 Aug, 2021
       
  • Acute thrombosis during carotid artery stenting caused by stent-induced
           kinking

    • Abstract: A case of a 71-year-old man with previous Transient Ischemic Attack (TIA), treated with stent implantation due to right internal carotid artery stenosis. The procedure was complicated by stenosis and kinking of the vessel distal to the stent and thrombus formation. The flow in the stented artery was not restored. A massive stroke occurred. The man died on the 3rd day after the procedure.
      PubDate: 10 May, 2021
       
  • To study prevalence of ankle and foot complex injuries in recreational
           barefoot and shod marathon runners: A cross- sectional study

    • Abstract: Background: Injuries occurring while running barefoot and shod has been a topic of concern for a long time due to the increased interest in recreational running. This research focused on the ankle and foot complex injuries in shod and barefoot running groups. The objective was to find the pattern of ankle and foot complex injuries and if any other aspects such as type of running or the frequency of training for marathons affect the occurrence of injuries.Methodology: 100 participants (83 shod and 17 barefoot) between the age of 18-60 years filled a self-made questionnaire on ankle and foot related injuries via electronic medium (Google form).Results: Plantar fasciitis, ankle sprain and peroneal tendinitis are the most common injuries in the ankle and foot complex. This can be attributed to by the reduced training frequency leading to ankle sprain and peroneal tendinitis. Majority participants were found to have a rearfoot strike pattern attributing to an increased risk of plantar fasciitis.Conclusion: Ankle sprain, plantar fasciitis, peroneal tendonitis, flat feet and metatarsal stress fractures are most commonly occurring. More research on this topic is encouraged with objective measurements.
      PubDate: 09 Sep, 2021
       
  • The case of acute psychotic episode treatment in patient with myasthenia
           gravis

    • Abstract: A seventy-one old male patient with no previous Hx of mental disorders including alcohol use and with no family Hx of mental disorders was admitted to psychiatric ward due to acute aggression, agitation, excessive irritability and lack olf sleep. He suferred from myasthenia gravis for years and was treated chronically with ambenonium 20 mg daily. Because of comorbidity of uveitis with macular edema he received treatment with prednisolone 70mg daily. Because of acute psychotic symptoms the treatment with olanzapine up to 20mg/d was introduced without effect. The treatment was switched to haloperidol 10mg/d with gradual improvement of patient’s behaviour. He was discharged from the hospital with indication to continue psychiatric, ohpthalomogic, and neurological outpatient care.
      PubDate: 09 Jun, 2021
       
  • Miliary Tuberculosis and Infective Endocarditis

    • Abstract: Background: Miliary Tuberculosis (MTB) is a potentially lethal disease if not diagnosed and treated early. Miliary tuberculosis infection in childhood remains a significant health problem in developing countries. Clinical manifestations are non-specific and therefore the condition may bemuse even the most experienced clinicians. Infective Endocarditis (IE) remains a lethal valvular heart disease and can be fatal if not treated promptly. Coagulase-negative staphylococci and oral streptococci are common causative organisms. Both conditions can be fatal independently but can present in the same patient. Since fever is a common symptom in both, one infection may mask the other. Tuberculous Endocarditis (TBE) is another rare entity with few documented cases and often presents with a miliary tuberculosis picture, especially in endemic countries.Case presentation: We report the case of a 9-year-old immunocompetent girl who presented with history of congenital heart disease, fever, malaise, and anemia for a duration of two months. Transthoracic Echocardiography (TTE) revealed a 10x7mm vegetation on the anterior mitral valve leaflet along with Mitral Stenosis (MS) mild Mitral Regurgitation (MR) and a Patent Ductus Arteriosus (PDA). Blood cultures grew streptococcus viridans. She was started on broad spectrum antibiotics but continued to be febrile along with drenching night sweats. Chest CT was consistent with miliary tuberculosis and a subsequent sputum for GeneXpert® test was positive. She was subsequently started on Anti-Tubercular Treatment (ATT). An eight week follow up showed resolution of the vegetation, improvement in symptoms, resolution of anemia and weight gain. Conclusion: This is a rare case of MTB and IE in an immunocompetent patient, without severe valvular destruction. MTB although rare should remain on the differential especially in endemic countries and in patients reporting a long duration of symptoms. MTB and IE can present in the same patient and must be differentiated from TBE since the management of the case differs.
      PubDate: 08 Sep, 2021
       
  • Cutaneous mastocytosis in an infant: Case report and clinicopathological
           correlation

    • Abstract: Mastocytosis is a disorder of clonal proliferation of the mast cells, which can be cutaneous or systemic. Abnormal mast cell infiltration comprising multifocal compact clusters or cohesive aggregates can affect one or more organ systems. Cutaneous mastocytosis is a relatively uncommon condition in the pediatric population. We report a case of 9 month infant presented with multiple papular and vesicular skin rashes since 6 months of age. On clinical examination Darier’s sign was negative. The serum tryptase levels were within normal limits. Clinical differential diagnoses were benign cephalic histiocytosis vs cutaneous mastocytosis. Skin biopsy revealed a mononuclear cell infiltrate in the papillary dermis reaching up to the dermo-epidermal junction. Toluidine blue staining highlighted the metachromatic granules. CD117, CD30 IHC stains were positive which confirmed the diagnosis of cutaneous mastocytosis. This case is presented to highlight the histomorphology and the special stains in cases of mastocytosis.
      PubDate: 07 Oct, 2021
       
  • Acute Flaccid Paralysis surveillance in Gaza Strip, Palestine

    • Abstract: Acute Flaccid Paralysis (AFP) is a clinical syndrome characterized by rapid onset of weakness, in the respiratory muscles, swallowing and limbs; and death because of respiratory muscles failure.AFP surveillance is crucial, the clinicians are required to notify AFP cases among children below 15 years old to the epidemiology department with completion of AFP surveillance form.In this study, the researcher analyzed AFP surveillance investigation forms to determine the clinical picture, viral etiology and the incidence of AFP among children under 15 years.Material and method (Study design): The research study conducted through cross sectional study, based on AFP investigation forms in the epidemiology department.Results: The final diagnosis of the cases were as follow, 71.1% “27 cases” were GBS, 10.5 % were Encephalitis, 7.9% were Neuropathy, 2.6% “ one case only” for each of the following Aseptic meningitis, Transverse myelitis, Tuphus fever and Subspinal muscular atrophy.The incidence rate among children less than 15 years old which range from 0.58 / 100.000 in 2006 to 1.2 / 100.000 in 2012; Most of the cases 89.5 % had fully vaccinated and 10.5% had not fully vaccinated due to their ages less than one year, 65.8 “25 cases” had residual weakness, all of the cases classified as discarded according to the expert committee decision; no one case dead, all of the samples sent to the Tal-Hashomir laboratory in the occupied land in 1948 for viral isolation; most of the results 81.6% revealed that no virus isolated, 11.8% isolated ECHO virus, 2.6% isolated Coxsachie virus and 4 % isolated NPEV.Conclusion: No wild polio virus in Palestine which is polio free since 1984 and certified in 2006, our success being attributed to: start of 2 doses of IPV and 5 doses of OPV since 1978, high immunization coverage more than 95% at district level and effective AFP surveillance system in Palestine. The study recommended to encourage polio immunization and all clinicians are required to report all AFP cases and submitting at least two stool samples to the epidemiology department (at least 24 hours apart within 14 days of onset of paralysis).
      PubDate: 07 Aug, 2021
       
  • Unilateral eyelid ptosis: A case report cured by Gelsemium sempervirens

    • Abstract: Background: A 60 years-old man presented with an 8-day history of acute onset painless left upper eyelid ptosis covering the pupil entirely. Ptosis can affect unilateral or bilateral. He had no other symptoms; importantly pupils were equal and reactive and eye movements were full. There was no palpable mass or swelling. He had a headache but had no other focal neurological signs or symptoms of fatigue. MRI of brain and Orbits showed no remarkable abnormality detected in brain & orbits. Objectives: Assessment of the homeopathic symptomatic aspects of Gelsemium sempervirens on eyelid ptosis. Showed homeopathy has a major role in the treatment of ptosis. Materials and Methods. The case management was conducted for 3 weeks and only two follow follow-ups were was taken according to the law of homeopathy. Result: Administrating Gelsemium sempervirens 30°C of 5/7 pills orally thrice a day for a week; left eyelid ptosis was improved 60%. The ptosis resolved quickly and the patient remains symptom-free 100% at 3 weeks follow-up by next high potency Gelsemium sempervirens 200C with the same pattern. Conclusion: Acute ptosis may indicate serious pathology. A careful history and examination must be taken. The appropriate management requires recognition of the underlying cause of it. This case presentation highlights the various aspects of ptosis evaluation and management by homeopathy for future study.
      PubDate: 04 Aug, 2021
       
  • Penetrating pharynx wound reaching mediastinum. Which is the proper
           surgical approach'

    • Abstract: We report the case of a knife penetrating wound from the hypopharynx-cervical esophagus area to the posterior mediastinum in a 91-year-old patient. The surgical approach for this patient required a transoral examination with direct laryngoscopy and a right cervicotomy. Although it was not necessary to perform a thoracotomy, the position of the knife, stuck towards the posterior mediastinum, made the presence of an interdisciplinary team in the operating room necessary.
      PubDate: 03 May, 2021
       
  • Complete response of merkel cell carcinoma with brain metastases to
           pembrolizumab and radiotherapy: A case report

    • Abstract: Merkel cell carcinoma is a rare, but highly malignant and fast growing skin-cancer with high recurrence-rates, deriving from endothelial and neuroendocrine tissues. For advanced Merkel cell carcinoma prognosis is poor [1] and even under cytotoxic chemotherapy there is only a median progression-free survival of only 3 months [2,3]. Even though Merkel cell carcinoma frequently shows lymphatic metastases, it almost never shows cerebral involvement [1]. To our knowledge there are only twelve reported cases of cerebral metastases. Furthermore this is the first reported case of complete response in a patient with advanced Merkel cell carcinoma Stage IV with brain metastases under combined treatment with pembrolizumab and radiotherapy.
      PubDate: 03 Jun, 2021
       
  • COVID-19 Pandemic: Past, present and future

    • Abstract: COVID-19 is the emerged pandemic disease of mankind. This disease yet has no proven therapy. Measures like the use of a vaccine, chemical spray, disinfectants, antiseptics, and supportive therapies could help control this disease that is caused by a coronavirus. Further effective control and prevention measures are urgently demanded to save the life of billions of the world’s human population. Especially having effective, and affordable vaccine that can be supplied as per its demand to all humankind is the priority at present.
      PubDate: 03 Jun, 2021
       
 
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