Subjects -> MEDICAL SCIENCES (Total: 8677 journals)
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MEDICAL SCIENCES (2410 journals)            First | 3 4 5 6 7 8 9 10 | Last

Showing 1201 - 1400 of 3562 Journals sorted alphabetically
Journal of Evidence-Based Integrative Medicine     Open Access   (Followers: 18)
Journal of Evidence-Based Medicine     Partially Free   (Followers: 4)
Journal of Exercise Science & Fitness     Open Access   (Followers: 29)
Journal of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
Journal of Family and Community Medicine     Open Access   (Followers: 3)
Journal of Family Medicine and Primary Care     Open Access   (Followers: 11)
Journal of Foot and Ankle Research     Open Access   (Followers: 5)
Journal of Forensic Science and Research     Open Access   (Followers: 2)
Journal of Gandaki Medical College-Nepal     Open Access  
Journal of Generic Medicines     Hybrid Journal   (Followers: 2)
Journal of Geographical Sciences     Hybrid Journal   (Followers: 1)
Journal of Global Antimicrobial Resistance     Hybrid Journal   (Followers: 3)
Journal of Hand Therapy     Hybrid Journal   (Followers: 19)
Journal of Head & Neck Physicians and Surgeons     Open Access   (Followers: 2)
Journal of Health & Medical Informatics     Open Access   (Followers: 61)
Journal of Health and Biological Sciences     Open Access   (Followers: 1)
Journal of Health Design     Open Access   (Followers: 1)
Journal of Health Economics and Outcomes Research     Open Access   (Followers: 1)
Journal of Health Promotion and Behavior     Open Access  
Journal of Health Research and Reviews     Open Access  
Journal of Health Science and Medical Research     Open Access  
Journal of Health Science Research     Open Access  
Journal of Health Sciences     Open Access   (Followers: 1)
Journal of health sciences     Open Access  
Journal of Health Sciences / Sağlık Bilimleri Dergisi     Open Access  
Journal of Health Sciences and Medicine     Open Access  
Journal of Health Sciences and Medicine     Open Access   (Followers: 2)
Journal of Health Sciences and Surveillance System     Open Access  
Journal of Health Sciences Scholarship     Open Access  
Journal of Health Specialties     Open Access  
Journal of Health Studies     Open Access  
Journal of Healthcare Informatics Research     Hybrid Journal   (Followers: 1)
Journal of Heavy Metal Toxicity and Diseases     Open Access  
Journal of Helminthology     Hybrid Journal   (Followers: 2)
Journal of Herbs Spices & Medicinal Plants     Hybrid Journal  
Journal of HIV for Clinical and Scientific Research     Open Access   (Followers: 2)
Journal of Hospital Medicine     Hybrid Journal   (Followers: 11)
Journal of Huazhong University of Science and Technology [Medical Sciences]     Hybrid Journal  
Journal of Human Hypertension     Hybrid Journal   (Followers: 3)
Journal of Human Rhythm     Open Access  
Journal of Human Transcriptome     Open Access  
Journal of Ideas in Health     Open Access  
Journal of Inflammation     Open Access   (Followers: 2)
Journal of Inflammation Research     Open Access  
Journal of Injury and Violence Research     Open Access   (Followers: 7)
Journal of Innovation in Health Informatics     Open Access   (Followers: 17)
Journal of Institute of Medicine     Open Access  
Journal of Insulin Resistance     Open Access   (Followers: 1)
Journal of Interactional Research in Communication Disorders     Hybrid Journal   (Followers: 5)
Journal of Interferon & Cytokine Research     Hybrid Journal   (Followers: 3)
Journal of International Medical Research     Open Access   (Followers: 3)
Journal of Interventional Medicine     Open Access   (Followers: 1)
Journal of Investigative Medicine     Hybrid Journal   (Followers: 3)
Journal of Islamabad Medical & Dental College     Open Access   (Followers: 2)
Journal of Istanbul Faculty of Medicine     Open Access  
Journal of Karnali Academy of Health Sciences     Open Access   (Followers: 1)
Journal of Kathmandu Medical College     Open Access   (Followers: 1)
Journal of King Abdulaziz University : Medical Sciences     Open Access   (Followers: 2)
Journal of Laboratory Medicine     Hybrid Journal   (Followers: 27)
Journal of Laryngology and Voice     Open Access   (Followers: 11)
Journal of Lasers in Medical Sciences     Open Access  
Journal of Law, Medicine & Ethics     Hybrid Journal   (Followers: 24)
Journal of Legal Medicine     Hybrid Journal   (Followers: 7)
Journal of Limb Lengthening & Reconstruction     Open Access  
Journal of Lumbini Medical College     Open Access   (Followers: 1)
Journal of Mahatma Gandhi Institute of Medical Sciences     Open Access  
Journal of Manipulative and Physiological Therapeutics     Hybrid Journal   (Followers: 6)
Journal of Manmohan Memorial Institute of Health Sciences     Open Access   (Followers: 1)
Journal of Marine Medical Society     Open Access  
Journal of Materials Science : Materials in Medicine     Hybrid Journal   (Followers: 4)
Journal of Maternal and Child Health     Open Access  
Journal of Mechanics in Medicine and Biology     Hybrid Journal  
Journal of Medical and Biological Engineering     Hybrid Journal   (Followers: 4)
Journal of Medical and Biomedical Sciences     Open Access   (Followers: 2)
Journal of Medical Case Reports     Open Access   (Followers: 1)
Journal of Medical Cases     Open Access   (Followers: 6)
Journal of Medical Colleges of PLA     Full-text available via subscription  
Journal of Medical Disorders     Open Access  
Journal of Medical Economics     Hybrid Journal   (Followers: 8)
Journal of Medical Education and Curricular Development     Open Access   (Followers: 6)
Journal of Medical Ethics     Partially Free   (Followers: 25)
Journal of Medical Ethics and History of Medicine     Open Access   (Followers: 17)
Journal of Medical Humanities     Hybrid Journal   (Followers: 21)
Journal of Medical Hypotheses and Ideas     Open Access  
Journal of Medical Imaging and Health Informatics     Full-text available via subscription   (Followers: 1)
Journal of Medical Investigation and Practice     Open Access  
Journal of Medical Laboratory and Diagnosis     Open Access  
Journal of Medical Law and Ethics     Full-text available via subscription   (Followers: 16)
Journal of Medical Microbiology     Full-text available via subscription   (Followers: 6)
Journal of Medical Sciences     Open Access  
Journal of Medical Sciences     Open Access  
Journal of Medical Screening     Hybrid Journal   (Followers: 6)
Journal of Medical Signals and Sensors     Open Access   (Followers: 3)
Journal of Medical Society     Open Access  
Journal of Medical Systems     Hybrid Journal  
Journal of Medical Toxicology     Hybrid Journal   (Followers: 6)
Journal of Medical Ultrasound     Open Access   (Followers: 2)
Journal of Medicinal Botany     Open Access  
Journal of Medicinal Chemistry     Hybrid Journal   (Followers: 203)
Journal of Medicine     Open Access   (Followers: 1)
Journal of Medicine and Biomedical Research     Open Access   (Followers: 1)
Journal of Medicine and Philosophy     Hybrid Journal   (Followers: 8)
Journal of Medicine and the Person     Hybrid Journal  
Journal of Medicine in Scientific Research     Open Access  
Journal of Medicine in the Tropics     Open Access  
Journal of Medicine Research and Development     Open Access   (Followers: 3)
Journal of Medicine, Physiology and Biophysics     Open Access   (Followers: 5)
Journal of Medicines Development Sciences     Open Access   (Followers: 1)
Journal of Metabolomics & Systems Biology     Open Access   (Followers: 2)
Journal of Mind and Medical Sciences     Open Access   (Followers: 1)
Journal of Molecular Medicine     Hybrid Journal   (Followers: 11)
Journal of Movement Disorders     Open Access   (Followers: 2)
Journal of Muscle Research and Cell Motility     Hybrid Journal   (Followers: 1)
Journal of Nanotechnology in Engineering and Medicine     Full-text available via subscription   (Followers: 6)
Journal of Nanotheranostics     Open Access   (Followers: 1)
Journal of Natural Medicines     Hybrid Journal  
Journal of Natural Science, Biology and Medicine     Open Access   (Followers: 3)
Journal of Nature and Science of Medicine     Open Access   (Followers: 4)
Journal of Negative and No Positive Results     Open Access  
Journal of Nepalgunj Medical College     Open Access  
Journal of Neurocritical Care     Open Access  
Journal of Neurodegenerative Diseases     Open Access   (Followers: 2)
Journal of Neurorestoratology     Open Access  
Journal of Neuroscience and Neurological Disorders     Open Access  
Journal of Nobel Medical College     Open Access  
Journal of Obesity and Bariatrics     Open Access   (Followers: 1)
Journal of Occupational Health     Open Access  
Journal of Occupational Therapy Education     Open Access   (Followers: 11)
Journal of Ocular Biology, Diseases, and Informatics     Hybrid Journal  
Journal of Oral Biology and Craniofacial Research     Full-text available via subscription  
Journal of Oral Health and Craniofacial Science     Open Access  
Journal of Orofacial Sciences     Open Access  
Journal of Otorhinolaryngology, Hearing and Balance Medicine     Open Access   (Followers: 1)
Journal of Ovarian Research     Open Access  
Journal of Ozone Therapy     Open Access  
Journal of Palliative Medicine     Hybrid Journal   (Followers: 47)
Journal of Paramedical Sciences & Rehabilitation     Open Access  
Journal of Parkinsonism and Restless Legs Syndrome     Open Access   (Followers: 2)
Journal of Parkinson’s Disease and Alzheimer’s Disease     Open Access   (Followers: 1)
Journal of Participatory Medicine     Open Access  
Journal of Patan Academy of Health Sciences     Open Access  
Journal of Pathogens     Open Access   (Followers: 1)
Journal of Patient Experience     Open Access  
Journal of Patient Safety and Risk Management     Hybrid Journal   (Followers: 2)
Journal of Patient-Centered Research and Reviews     Open Access  
Journal of Patient-Reported Outcomes     Open Access  
Journal of Periodontal Research     Hybrid Journal  
Journal of Personalized Medicine     Open Access   (Followers: 3)
Journal of Pest Science     Hybrid Journal   (Followers: 1)
Journal of Pharmaceutical Policy and Practice     Open Access   (Followers: 4)
Journal of Physiobiochemical Metabolism     Hybrid Journal   (Followers: 2)
Journal of Physiology-Paris     Hybrid Journal   (Followers: 2)
Journal of Pioneering Medical Sciences     Open Access  
Journal of Postgraduate Medicine     Open Access  
Journal of Pregnancy     Open Access   (Followers: 4)
Journal of Prevention & Intervention Community     Hybrid Journal   (Followers: 6)
Journal of Preventive Medicine and Public Health     Open Access  
Journal of Primary Prevention     Hybrid Journal   (Followers: 7)
Journal of Prosthodontic Research     Full-text available via subscription   (Followers: 1)
Journal of Prosthodontics     Hybrid Journal   (Followers: 2)
Journal of Receptor, Ligand and Channel Research     Open Access   (Followers: 1)
Journal of Regenerative Medicine     Partially Free   (Followers: 4)
Journal of Research in Medical Sciences     Open Access   (Followers: 2)
Journal of Science and Applications : Biomedicine     Open Access   (Followers: 1)
Journal of Science and Technology (Ghana)     Open Access   (Followers: 3)
Journal of Scientific Innovation in Medicine     Open Access  
Journal of Scientific Perspectives     Open Access   (Followers: 1)
Journal of Sensory Studies     Hybrid Journal   (Followers: 4)
Journal of Shaheed Suhrawardy Medical College     Open Access  
Journal of Shoulder and Elbow Arthroplasty     Open Access  
Journal of Sleep Disorders : Treatment & Care     Hybrid Journal   (Followers: 10)
Journal of South American Earth Sciences     Hybrid Journal   (Followers: 5)
Journal of Spinal Cord Medicine     Hybrid Journal   (Followers: 4)
Journal of Spinal Disorders & Techniques     Hybrid Journal   (Followers: 2)
Journal of Sports Medicine and Allied Health Sciences : Official Journal of the Ohio Athletic Trainers Association     Open Access   (Followers: 1)
Journal of Stem Cell Therapy and Transplantation     Open Access   (Followers: 1)
Journal of Stomal Therapy Australia     Full-text available via subscription  
Journal of Strength and Conditioning Research     Hybrid Journal   (Followers: 77)
Journal of Substance Use     Hybrid Journal   (Followers: 15)
Journal of Surgical Academia     Open Access   (Followers: 1)
Journal of Surgical and Clinical Research     Open Access  
Journal of Surgical Case Reports     Open Access  
Journal of Surgical Education     Full-text available via subscription   (Followers: 3)
Journal of Surgical Technique and Case Report     Open Access  
Journal of Systemic Therapies     Full-text available via subscription   (Followers: 3)
Journal of Taibah University Medical Sciences     Open Access  
Journal of Telemedicine and Telecare     Hybrid Journal   (Followers: 12)
Journal of The Academy of Clinical Microbiologists     Open Access  
Journal of the American Association for Laboratory Animal Science     Full-text available via subscription   (Followers: 9)
Journal of the American College of Certified Wound Specialists     Hybrid Journal   (Followers: 2)
Journal of the American College of Clinical Wound Specialists     Hybrid Journal   (Followers: 2)
Journal of the American Medical Directors Association     Hybrid Journal   (Followers: 5)
Journal of the American Medical Informatics Association : JAMIA     Hybrid Journal   (Followers: 36)
Journal of the American Podiatric Medical Association     Full-text available via subscription   (Followers: 7)
Journal of the Anatomical Society of India     Full-text available via subscription  
Journal of the Anus, Rectum and Colon     Open Access  
Journal of The Arab Society for Medical Research     Open Access  
Journal of the Australasian College of Nutritional and Environmental Medicine     Full-text available via subscription  
Journal of the Australasian Society of Aerospace Medicine     Open Access   (Followers: 1)
Journal of the Ceylon College of Physicians     Open Access  

  First | 3 4 5 6 7 8 9 10 | Last

Similar Journals
Journal Cover
Journal of Medicine in Scientific Research
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2537-091X - ISSN (Online) 2537-0928
Published by Medknow Publishers Homepage  [427 journals]
  • Welcome Message

    • Authors: Hany Nasr
      Pages: 1 - 1
      Abstract: Hany Nasr
      Journal of Medicine in Scientific Research 2018 1(1):1-1

      Citation: Journal of Medicine in Scientific Research 2018 1(1):1-1
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_14_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Editor-in-Chief

    • Authors: Samir Halim
      Pages: 2 - 2
      Abstract: Samir Halim
      Journal of Medicine in Scientific Research 2018 1(1):2-2

      Citation: Journal of Medicine in Scientific Research 2018 1(1):2-2
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_15_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • The efficacy of argon plasma coagulation in the treatment of gastric
           antral vascular ectasia in Mataria teaching hospital

    • Authors: El Saied E Shabaan, Tarek A Fouad, Aisha El-Shimy
      Pages: 3 - 7
      Abstract: El Saied E Shabaan, Tarek A Fouad, Aisha El-Shimy
      Journal of Medicine in Scientific Research 2018 1(1):3-7
      BackgroundGastric antral vascular ectasia (GAVE) is characterized by mucosal and submucosal vascular ectasia. It may present with iron-deficiency anemia or gastrointestinal bleeding. Argon plasma coagulation (APC) may be used for treating GAVE. This study aims to evaluate the efficacy and safety of APC in the treatment of GAVE.Patients and methodsA total of 30 patients with GAVE and in need of treatment for bleeding or anemia were treated with APC every 2 to 4 weeks until eradication of GAVE or cessation of the patient's initial symptoms. They were then followed up on a monthly basis for recurrence of initial symptoms or blood transfusion and measurement of hemoglobin levels. Follow-up endoscopy was done after 6 months.ResultsAmong the thirty patients who were included in the study, GAVE was associated with underlying cirrhosis in 18 (60%) patients. Indications for treatment were hematemesis and/or melena in 16 (53.3%) patients and iron-deficiency anemia in 14 (46.6%) patients. A total of 78 APC sessions were conducted for the treatment of GAVE (2.6 sessions per patient, range: 1–6 sessions). Successful endoscopic eradication of GAVE was achieved in 11 of 30 patients (36.6%). Seventeen (56.6%) patients showed improvement in the severity of GAVE from endoscopic evaluation with cessation of the patient's initial symptoms, highly significant reduction of blood transfusion, and an improvement in hemoglobin levels (highly significant). Only two (6.6%) patients showed no improvement in the severity of GAVE from endoscopic evaluation with the continuation of the patient's initial symptoms (bleeding). No endoscopy-related adverse events were found during the study period.ConclusionEndoscopic APC is safe and effective in treating GAVE with a significant reduction in the need for blood transfusion and an improvement in hemoglobin levels, but endoscopic eradication rate of GAVE is low (36.6%).
      Citation: Journal of Medicine in Scientific Research 2018 1(1):3-7
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_3_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Technical aspect of mechanical thrombectomy of acute ischemic stroke

    • Authors: Magdy Khalaf, Ahmed El-Bassiouny, Romany Adly
      Pages: 8 - 12
      Abstract: Magdy Khalaf, Ahmed El-Bassiouny, Romany Adly
      Journal of Medicine in Scientific Research 2018 1(1):8-12
      Background and purposeMechanical thrombectomy was recently reported of having the potential to treat acute ischemic stroke. However, few comparative studies on neurothrombectomy devices are reported. This study aims to compare two retrievable stent systems according to their safety and effectiveness in patients with acute ischemic stroke.Patients and methodsIn this study, the clinical, radiological, and functional outcomes of 20 patients with acute ischemic stroke are compared prospectively. Patients were treated with either Trevo retriever (TR) or Solitaire stent (ST) according to the neurointerventionalist preference. Successful recanalization was defined as thrombolysis in cerebral ischemia grade 2a to 3.ResultsRevascularization was achieved in seven (70%) patients in the ST group and six (60%) in the TR group. The rate of symptomatic intracerebral hemorrhage was 20% in the ST group and 30% in the TR group. One (10%) patient died during the first week in the TR group and one (10%) patient in the ST group. The rate of good outcome was 60 and 70% for TR and ST groups, respectively.ConclusionOur study showed no significant differences between both stent retrievers. Moderately high recanalization rates are possible with both; however, larger series may depict safety-related variations.
      A picture of thrombus removed by stent from the first pass.
      Digital angiography anteroposterior view showed complete occlusion of left middle cerebral artery.
      Digital angiography anteroposterior view after mechanical thrombectomy showed recanalization of left middle cerebral artery.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):8-12
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_4_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Biomechanical assessment of the preperitoneal hernial repair by a
           bipedicled external oblique aponeurotic flap: mobility of the floor of the
           inguinal canal

    • Authors: Mohamed M Moneer, Adel K Barsoum, Soheir S Makarem
      Pages: 13 - 16
      Abstract: Mohamed M Moneer, Adel K Barsoum, Soheir S Makarem
      Journal of Medicine in Scientific Research 2018 1(1):13-16
      IntroductionDevelopment of indirect inguinal hernias through the inguinal canal is usually prevented by the shutter and the sphincteric mechanisms, which are known to be destroyed by almost all anterior herniorrhaphies.ObjectiveA new preperitoneal repair, which uses a bipedicled external oblique oponeurotic flap, has been recently introduced and was suggested to change the mechanics of this area. In this hernia repaires, the biomechanics of the inguinal region were assessed in healthy individuals and in patients with hernia after new repair and after other conventional anterior hernial repairs.MethodsThe study included 20 patients with inguinal hernias and 5 non-hernia control cases (group A). Ten of the hernia cases were repaired by the new preperitoneal repair (group B) wheareas the other 10 were repaired by convemtional anterior repair (modified Bassini) (group C). The 5 control cases were selected from patients without hernia, who were scheduled for inguinal surgery for excision of symptomatic varicoceles. During surgery in all cases, two ligaclips were inserted into the ileopubic tract. After sound healing, all cases were radiographed to detect any change in the position of the ligaclips, on contraction of the external oblique muscle. Any displacement of the inserted ligaclips was considered in this study as a sort of mobility at the floor of the inguinal canal, induced by the contracted muscle.ResultsThe study showed that contraction of the external oblique muscle induced, in all cases, a degree of an upward displacement of the floor of the inguinal canal, which could be called a reversed shutter movement. The magnitude of this reversed shutter mobility was nearly identical in normal controls and in cases that underwent conventional anterior hernial repairs.ConclusionThe new preperitoneal repair, with the bipedicled external oblique oponeurotic flap, was found to augment this reversed shutter movement significantly. The possible explanation and the forces that possibly induced this reversed shutter mechanism are herein presented and discussed.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):13-16
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_5_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Outcome of cochlear implantation in children with enlarged vestibular
           aqueduct (EVA) and mondini dysplasia (incomplete partition type II)

    • Authors: Ihab Sefein, Amr Younes, Abir Omara, Soha Hamada, Azza Sami, Iman ELRouby
      Pages: 17 - 25
      Abstract: Ihab Sefein, Amr Younes, Abir Omara, Soha Hamada, Azza Sami, Iman ELRouby
      Journal of Medicine in Scientific Research 2018 1(1):17-25
      BackgroundCongenital inner ear abnormality is a major cause of sensorineural hearing loss in children, about 20% of children with congenital sensorineural hearing loss (SNHL) have associated malformations of the temporal bone, and increased experience in cochlear implantation has led to more children with abnormal cochleo-vestibular anatomy submitted to this procedure.AimTo evaluate the outcome of cochlear implantation in cases with enlarged vestibular aqueduct (EVA) and Mondini deformity (incomplete partition type II) following cochlear implantation and comparing the results with cochlear implant cases without inner ear anomalies.Patients and methods69 children all less than 6 years of age, CI surgeries underwent from April 2014 to December 2015 at the National Hearing & Speech institute (HSI) Giza-Egypt. Eight patients were congenital prelingual severe to profound hearing loss with enlarged vestibular aqueduct (EVA) and Mondini deformity (incomplete partition type II) Isolated EVA was detected in four cases, two cases with bilateral incomplete partition type II (Mondini deformity) and two cases with bilateral incomplete partition II (Mondini deformity) associated with dilated vestibule & vestibular aqueducts bilaterally with short lateral, SCC (semicircular canal), Beside those 8 cases, a random sample (16 control cases) . The ECAP thresholds determined with neural response telemetry (NRT) or Auditory response threshold (ART) software provide a good starting point for locating the behavioral T and C levels. Auditory skills were evaluated before start of rehabilitation and after 6 months of rehabilitation using LittlEARS Questionnaire and Auditory Checklists and compared to the auditory skills of other cochlear implantees with normal inner ear. Results: This study showed that the auditory skills and audiological performance of children with congenital ear anomalies developed over a period of 6 months after cochlear implantation, in a similar manner to those of young children with radiologically normal inner ears.ConclusionCochlear implantation can be successfully performed in children with enlarged vestibular aqueduct (EVA) and Mondini dysplasia (incomplete partition type II) .These children and their parents can expect significant auditory benefits from this intervention.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):17-25
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_7_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Ovulation induction in women with polycystic ovarian syndrome: Clomiphene
           citrate or letrozole?

    • Authors: Mohamed Y Elsemary, Waleed F G. Mostafa, Osama S El Taher
      Pages: 26 - 29
      Abstract: Mohamed Y Elsemary, Waleed F G. Mostafa, Osama S El Taher
      Journal of Medicine in Scientific Research 2018 1(1):26-29
      ObjectiveThe objective of this study was to determine first-line infertility therapy in polycystic ovarian syndrome (PCOS) and to compare between clomiphene citrate (CC) and aromatase inhibitors (letrozole) as the standard treatment.Patients and methodsThis is a prospective randomized study. The study was conducted at El-Galaa Assisted Reproduction Unit, El-Galaa Maternity Teaching Hospital, Cairo, Egypt. Eighty-eight women with PCOS were randomized into two groups. Rotterdam criteria were used to define PCOS: oligomenorrhea less than or equal to 8 menses/year plus either PCOS on ultrasound or clinical/biochemical hyperandrogenism, with the exclusion of other causes. Forty-four patients were randomized to the letrozole group (82 cycles), and the other 44 were randomized to the CC group (78 cycles). The aromatase inhibitor letrozole (5 mg/day) and CC (100 mg/day) were administered orally on days 3–7 of menses.ResultsNumber of follicles, endometrial thickness, estradiol levels on human chorionic gonadotropin day, and pregnancy rates were measured in both groups. The mean age, parity, and duration of infertility in both groups were similar. The number of follicles sized more than 15 mm in diameter was statistically significantly higher in the CC group (3.4 ± 0.4 vs. 2.03 ± 0.2). Ovulation occurred in 68.2% (56/82) of letrozole cycles and 74.3% (58/78) of CC cycles without a statistically significant difference. Median serum estradiol concentrations were significantly higher in the CC group than in the letrozole group (396 ± 84.4 vs. 266.2 ± 55.1 pg/ml). Endometrial thickness by transvaginal ultrasound at the time of human chorionic gonadotropin administration was not statistically significantly different in the two groups (7.8 ± 2.2 and 8.1 ± 1.2 mm in letrozole and CC groups, respectively). The pregnancy rate per cycle was 9.7% in the letrozole group and 7.6% in the CC group without significant statistical difference between the groups.ConclusionBoth letrozole and CC have comparable results, with no specific advantage of one over the other for ovulation induction in women with PCOS.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):26-29
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_19_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Serum antimullerian hormone before and after laparoscopic excision of
           ovarian endometrioma

    • Authors: Yousef M Elsemary, Waleed F G. Mostafa, Osama S El Taher, Hossam El-Din Mahmoud, Rania H Aly
      Pages: 30 - 34
      Abstract: Yousef M Elsemary, Waleed F G. Mostafa, Osama S El Taher, Hossam El-Din Mahmoud, Rania H Aly
      Journal of Medicine in Scientific Research 2018 1(1):30-34
      BackgroundSurgery of ovarian endometrioma may have a detrimental effect on ovarian reserve. This study aims to evaluate the effect of laparoscopic cystectomy on serum antimullerian hormone (AMH) in patients with endometrioma.Materials and methodsA prospective study was performed at El-Galaa Maternity Teaching Hospital where 60 women with endometriomas underwent laparoscopic cystectomy. Serum AMH, follicle-stimulating hormone (FSH), luteinizing hormone, estradiol, and antral follicle count (AFC) were measured preoperatively and at 3 months postoperatively.Outcome measuresThe ovarian reserve was measured based on the change of AMH level before and after surgery. Moreover, the secondary end point was to detect the changes in FSH, luteinizing hormone, estradiol, and AFC.ResultsSerum AMH decreased significantly from the baseline (4.12 ± 3.41) to 3 months postoperatively (2.62 ± 2.7). The AFC increased significantly from the baseline to 3 months after the operation.ConclusionLaparoscopic cystectomy of ovarian endometriomas causes a significant decline in serum AMH level and a significant increase in the level of FSH.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):30-34
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_20_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Identification of different bacterial species isolated from infected renal
           stones and evaluation of its uricolytic activity

    • Authors: Hala I Mohamed, Aisha El-Shimy, Azza Omran, Iman Kamel, Emad El-Tair
      Pages: 35 - 40
      Abstract: Hala I Mohamed, Aisha El-Shimy, Azza Omran, Iman Kamel, Emad El-Tair
      Journal of Medicine in Scientific Research 2018 1(1):35-40
      BackgroundNephrolithiasis remains a public health problem around the world, affecting up to 20% of the population. There are many risk factors that increase one's susceptibility to kidney stone formation. These include specific food, urinary tract infection, kidney disorders, and metabolic disorder. Also, some people with a family history of kidney stones may be more susceptible to develop stones.ObjectiveThe aim was to isolate, purify, and identify bacteria from urinary stones. Also, determine the most bacterial isolate secreting uricase enzyme.Patients and methodsA total of 100 cases were included in the study (66 men, 34 women) at the National Institute of Urology and Nephrology, Nephrology Department. Urine and stone culture identification of bacteria and purification of uricase enzyme.ResultsThe study showed that there was the highest percentage of stones within the greater than 40 years age group and uric acid stones constitute the highest incidence (40%). The highest percentage of bacterial isolates was Klebsiella spp. (25%). Klebsiella pneumonia was the most potent uricase producer, out of all bacterial species isolated from human urine.ConclusionThe study reported that uric acid stones were significantly affected by the uricase enzyme.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):35-40
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_10_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Value of toll-like receptor 3 (TLR3) in chronic kidney disease patients
           with hepatitis C virus infection

    • Authors: Aisha El-Shimy, Hala Ibrahim, Iman Kamel, El-Saied Shabaan, Tarek Fouad
      Pages: 41 - 47
      Abstract: Aisha El-Shimy, Hala Ibrahim, Iman Kamel, El-Saied Shabaan, Tarek Fouad
      Journal of Medicine in Scientific Research 2018 1(1):41-47
      BackgroundHepatitis C virus (HCV) infection is a severe public health problem with a worldwide predominance of 3%. An estimated 5–20% of infected patients develop cirrhosis annually, and 1–4% of them develop hepatocellular carcinoma. In Egypt, the prevalence of HCV antibody and HCV RNA are 10.0 and 7.0%, respectively, in the 15–59 years age group. In children of 1–14 years old, the prevalence of HCV antibody and HCV RNA are 0.4 and 0.2%, respectively. HCV infection is a cause of chronic kidney disease (CKD) and results in a significant problem in hemodialysis (HD) patients. Toll-like receptors (TLRs) might have an essential role in the pathogenesis of renal diseases. They include TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9, TLR10, TLR11, TLR12, and TLR13, though the latter two are not found in humans. Recently, it is shown that the mouse and human kidney tubular epithelial cells appear to express TLR3 constitutively and upregulate its expression upon challenge with its legend. For this reason, it appears conceivable that this receptor might play an essential role in this organ in health and disease.AimThe present study was carried out to determine the value of TLR3 in CKD patients with HCV infection. Also, we aimed to study the levels of TLR3 for Child–Pugh different classes to determine its impact on the prognosis of liver disease in those patients.Patients and methodsAll participants were selected from the National Institute of Urology and Nephrology. Their ages ranged between 40 and 62 years. Our study included 130 individuals of which 105 patients were selected from a dialysis unit with the end-stage renal disease on regular HD three times/week for at least 1 year and 25 healthy participants as a control group. They were divided into three groups. The control group (GI) consisted of 25 clinically healthy participants matched for age and sex; GII constituted 45 HCV negative patients; and GIII had 60 HCV positive patients. GIII was subclassified into GIIIA, GIIIB, and GIIIC, each of which consisted of 20 patients according to the Child–Pugh scoring. All patients and control samples were subjected to the following tests: Antibody screening for HCV using the ELISA technique and quantitative HCV RNA by PCR. Detection of TLR3 was done using the ELISA technique. Other parameters such as Complete Blood Picture (CBC), Prothrombin Time (PT) (INR), urea, creatinine, Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), total bilirubin, alkaline phosphatase, albumin, cholesterol, and triglycerides levels were also estimated.ResultsThe percentage of HCV-positive cases among a studied group of patients on HD was 57.2%, and the percentage of negative cases was 42.8%. There was no significant difference between GI, GII, and GIII as regards age and duration of dialysis. There was a highly significant difference between GIII as regards TLR3, INR, urea, total bilirubin, albumin, and triglycerides compared with GI and GII. There was a highly significant positive correlation of TRL3 with creatinine and PCR RNA and a significant negative correlation with albumin and cholesterol. We also found that there was a highly significant difference between GIIIC as regards INR, total bilirubin, and albumin compared with GIIIA and GIIIB. TLR3 showed no significant difference between GIIIA, GIIIB, and GIIIC.ConclusionTLR3 may have a role in the pathogenesis of HCV infection-related CKD and can be used as a new marker for the development of HCV related end-stage renal disease.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):41-47
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_11_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Effect of Kinesio taping therapy on waist circumferences in postpartum
           women

    • Authors: Maha M Mady
      Pages: 48 - 53
      Abstract: Maha M Mady
      Journal of Medicine in Scientific Research 2018 1(1):48-53
      ObjectiveThe study was designed to examine the effect of Kinesio taping (KT) on abdominal circumferences in postpartum women with or without diastasis of rectus abdominus muscles (DRAM).Participants and methodsA total of 26 women at 8 weeks postpartum, their age ranged from 25 to 35 years, their BMI was between 26.6 and 38.2 kg/m2, suffering from increasing abdominal circumferences with or without DRAM, were referred from the outpatient clinic of the Gynecological Department of Shibeen El-Kom Teaching Hospital, All women received KT therapy on the abdomen. The treatment was applied for 4 consecutive weeks. Evaluation was done for all women before the start of the study, every week, and after 4 weeks of KT to evaluate their waist circumferences.ResultsThere was a highly significant decrease in waist circumferences for the studied group, which was more apparent in younger women (age < 30 years), who had spontaneous vaginal delivery and in those complaining of DRAM.ConclusionThe results of this study testified that KT is an effective method in reducing abdominal circumferences in postpartum women with or without DRAM.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):48-53
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_12_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Evaluation of nutrition intake of football players

    • Authors: Hoda M El Gezrey, Heba S Abdelhaliem
      Pages: 54 - 58
      Abstract: Hoda M El Gezrey, Heba S Abdelhaliem
      Journal of Medicine in Scientific Research 2018 1(1):54-58
      IntroductionDespite football being the most popular sport in Egypt, most players do not know their needed nutritional requirements. The metabolic rate and energy consumption increased dramatically in football players. Thus, nutrition plays a significant role in improving the performance and the quality of life for these players.ObjectiveThis study aimed to assess the nutritional status of 50 football players aged between 15 and 19 years in Gomhorya Club – Menoufia.Participants and methodsDietary intake was evaluated for 7 days by using dietary assessment tools (24-h recall). This data was used to determine energy, macronutrients, micronutrients, and fiber. The weight and height were measured.ResultsThe results have shown that the football players had a high intake of energy and macronutrients. The protein intake was between 15 and 25%, fat 25 and 30%, and carbohydrate was between 60 and 65% of daily energy intake, and showed that they had a lower intake of vitamin D, calcium, and zinc.ConclusionThe football players need to correct their food habits by using group nutrition education, and this will improve their health and performance.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):54-58
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_13_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Association study between polymorphisms of dopamine transporter gene
           (SLC6A3), dopamine D1 receptor gene (DRD1), and autism

    • Authors: Azza Abdel Aziz Azzam, Dina Mohammad Rasheed Bahgat, Rasha Mohamad Hosny Shahin, Ranaih Massoud Azme Nasralla
      Pages: 59 - 65
      Abstract: Azza Abdel Aziz Azzam, Dina Mohammad Rasheed Bahgat, Rasha Mohamad Hosny Shahin, Ranaih Massoud Azme Nasralla
      Journal of Medicine in Scientific Research 2018 1(1):59-65
      IntroductionAutism is an etiologically and clinically heterogeneous group of disorders, collectively referred to as 'autism spectrum disorders'. Dopamine (DA) modulates a wide variety of processes, functions, and behaviors that are abnormal in individuals with autism spectrum disorders. The DA transporter gene SLC6A3 (solute carrier family 6, member 3) is a crucial regulator of DA homeostasis and neurotransmission. SLC6A3 gene has many polymorphisms which are associated with hangs in gene expression that may affect extracellular DA levels. The rs2550936 single-nucleotide polymorphism (SNP) at SLC6A3 gene decreased SLC6A3 expression or DA transporter availability. Also, the rs4532 SNP at dopamine D1 receptors (DRD1) is apparently a good candidate for affecting autism risk or modifying the classical symptoms of autism.AimThis study aimed to analyze the association between rs2550936 SNP at SLC6A3 gene and rs4532 SNP at the DRD1 gene and autism and their association with various demographical and clinical data of autistic children.Patients and methodsThis study included 50 autistic patients (36 males and 14 females) and 50 age-matched and sex-matched nonautistic controls for comparison. All patients were subjected to history taking, physical examination, language assessment, intelligence quotient, and childhood autism rating scale as well as analysis of SLC6A3 gene rs2550936 SNP and DRD1 gene rs4532 SNP using PCR–restriction fragment length polymorphism (RFLP), which was done for both patients and nonautistic controls.ResultsThere has been a statistically significant relationship between the age of mother and different genotypes of SLC6A3 gene in autistic patients (P = 0.030). DRD1 rs4532 A/G and A/A genotype frequencies were significantly higher in autistic patients (52%) compared with nonautistic controls (40%) (P = 0.043).ConclusionDRD1 rs4532 polymorphism might be a risk factor increasing autism susceptibility as well as the association of the patient age with its different genotypes. There was a significant difference in the mother's age at conception and different genotypes of the SLC6A3 gene in autistic patients.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):59-65
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_8_18
      Issue No: Vol. 1, No. 1 (2018)
       
  • Evaluation of oxytocin and serotonin levels in autism spectrum disorder

    • Authors: Golnar Oteify, Amal El-Ramly, Azza Samy, Eman Soliman
      Pages: 66 - 71
      Abstract: Golnar Oteify, Amal El-Ramly, Azza Samy, Eman Soliman
      Journal of Medicine in Scientific Research 2018 1(1):66-71
      ObjectiveAutism spectrum disorder (ASD) is a complex neurological and developmental disorder that affects how a person acts and interacts, communicates with others, and learns. Endocrine and neuropeptide factors are some among the list of possible etiologic or predisposing contenders. Abnormalities in the brain serotonin system are reported in ASD, including evidence of altered serotonin synthesis and receptor binding, as well as dystrophic serotonergic axons. Blood oxytocin levels are also a focus of ASD research. This work aimed to assess oxytocin and serotonin levels as biomarkers in individuals with ASD.Participants and methodsSerotonin and oxytocin levels, as biochemical parameters related to neurochemistry, were determined in the sera of 40 autistic patients (29 males and 11 females). They were categorized as mild to moderate and severe as indicated by their Childhood Autism Rating Scale and as low average intelligence, slow learner, and mentally retarded according to their intelligence quotients. The parameters were then compared with that of 40 age-matched and sex-matched control samples (30 males and 10 females).ResultsOur patients showed a highly significant increase in serotonin levels and a highly significant decrease in oxytocin levels as compared to controls. Diagnostic validity test was carried out for both serotonin and oxytocin and showed excellent results. A correlation done between serotonin and oxytocin levels among the patient group showed significant negative correlation.ConclusionOur results significantly reinforce the reliability of increased serotonin blood levels and decreased oxytocin levels as biomarkers in ASD, providing possible indications potentially useful for their inclusion in multimarker diagnostic panels for clinical use. Identifying relationships between identified ASD biomarkers may be a useful approach to connect the different findings of multiple systems in this heterogeneous disorder and to find the causesof ASD and to identify potential interventions.
      Citation: Journal of Medicine in Scientific Research 2018 1(1):66-71
      PubDate: Tue,24 Apr 2018
      DOI: 10.4103/JMISR.JMISR_9_18
      Issue No: Vol. 1, No. 1 (2018)
       
 
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