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Health Science Journal of Indonesia
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This is an Open Access Journal

Open Access journal
ISSN (Print) 2087-7021 - ISSN (Online) 2338-3437
Published by Badan Penelitian dan Pengembangan Kesehatan

[6 journals]

Intake of Kidney Bean (Phaseolus Vulgaris) Extract as Postpartum Blues
Management
- Authors: Nina Nikmah; Nina Nikmah, Khoiriyah Noviastuti
  Abstract: Background: Postpartum blues is a condition experienced by postpartum women. Women who experience postpartum blues are usually more prone to crying, more anxious, often unstable and more emotional than usual. Administration of supplement of kidney bean (Phaseolus Vulgaris) extract which has the highest zinc content, is a one of the method to improve the mood of mothers with postpartum blue. This study aimed to examining the effect of intake kidney bean extract (Phaseolus Vulgaris) as a zinc source as management mother with Postpartum Blues Methods: This was a quantitative study with an experimental study design (Quasi Experiment Design) with a Pre and Post-test Control Group Design. The instrument used measuring the mood of a woman after childbirth was EPDS (Edinburgh Post-Partum Depression Scale). The sample was 68 mother who experienced postpartum blues in Ngerandu Ponorogo primary health care. The Mann-Whitney was used to analyzed and finded out the difference in mood improvement before and after the intervention in the experimental group and the control group. Results: The results showed that there was a statistically significant difference in mood levels of mother with postpasrtum blues before and after intervention with p value of 0.001 (<0.005). This result indicated that intake of kidney bean (Phaseolus Vulgaris) extract had an effect on the mood level of women with postpartum blue. Conclusion: Intake of kidney bean (Phaseolus Vulgaris) extract on the incidence of postpartum blues possibly improvement in the mood of women with postpartum blues in the experimental group after the treatment for 1 month. Keywords: Kidney bean (Phaseolus Vulgaris) extract, Postpasrtum blues, Mother. Abstrak Latar belakang: Postpartum blues merupakan suatu kondisi yang terjadi pada ibu setelah melahirkan (postpartum). Seorang wanita yang mengalami postpartum blues biasanya lebih memiliki kondisi yang sering menangis, khawatir yang berlebihan, emosional yang tidak stabil dibandingkan seharusnya. Pemberian suplementasi ektrak kacang merah (Phaseolus Vulgaris) yang mana memiliki sumber nutrisi zinc yang tinggi, yang mana merupakan salah satu metode untuk merubah mood ibu dengan postpartum blues. Penelitian ini bertujuan untuk menguji efek konsumsi ekstrak kacang merah (Phaseolus Vulgaris) yang mana sebagai sumber zinc sebagai manajemen ibu dengan postpartum blues Metode: Merupakan penelitian kuantitatif dengan design penelitian Quasi Experiment dengan pre dan post control grup. Instrumen yang digunakan untuk mengukur moos ibu setelah melahirkan adalah EPDS (Edinburgh Post-Partum Depression Scale). Total sampel pada penelitian ini adala 68 ibu yang mengalami postpartum blues di Puskesmas Ngerandu Ponorogo. Analisis statistik menggunakan Mann-Whitney untuk menemukan perbedaan perubahan mood ibu postpartum blues sebelum dan sesudah dilakukan intervensi pada grup intervensi dan kontrol. Hasil: Hasil penelitian ini menunjukkan bahwa secara statistic terdapat perbedaan yang signifikan pada tingkat mood ibu dengan postpartum blues sebelum dan sesudah dilakukan intervensi dengan nilai p : 0,001 (<0,005). Hasil ini mengindikasikan bahwa konsumsi ekstrak kacang merah (Phaseolus Vulgaris) memiliki efek pada tingkat mood ibu yang sedang mengalami postpasrtum blues. Kesimpulan: Konsumsi ekstrak kacang merah (Phaseolus Vulgaris) pada kejadian ibu yang mengalami postpartum blues memungkinkan untuk perubahan mood ibu dengan postpartum blues pada grup intervensi setelah diberikan treatmen selama 1 bulan. Kata kunci: Ekstrak kacang merah (Phaseolus Vulgaris), Postpartum Blues, Ibu
  PubDate: Mon, 10 Jan 2022 02:31:38 SE A
Front Matter HSJI Volume 12 no.2 2021
- Authors: hsji author
  Abstract: Front Matter HSJI Volume 12 no.2 2021
  PubDate: Thu, 06 Jan 2022 03:51:23 SE A
  Issue No: Vol. 12 (2022)
Back Matter HSJI Volume 12 no.2 2021
- Authors: hsji author
  Abstract: Back Matter HSJI Volume 12 no.2 2021
  PubDate: Thu, 06 Jan 2022 00:00:00 SE A
  Issue No: Vol. 12 (2022)
Association between Smoking Duration, Sleeping Disorders, and Nutritional
Status in Indonesian Adult Men: Indonesia Family Life Survey 2014 Data
Analysis
- Authors: Relawantria Harlianti; Trias Mahmudiono, Dominikus Raditya Atmaka, Siti Helmyati, Mira Dewi, Cindra Tri Yuniar
  Abstract: Background: In Indonesia, the prevalence of smoking is increasing from year to year and can cause various health problems, such as sleep disorders and affect a person's nutritional status. So, in this study, the relationship between smoking duration, sleep disturbances, and nutritional status in men aged 26–45 years will be investigated using secondary data from the 2014 Indonesia Family Live Survey (IFLS). Methods: The 2014 secondary data from the fifth waves of the Indonesian Family Life Survey (IFLS) 2014 were used for analysis. All 6.929 data of men aged 26–45 years who provided anthropometric, smoking duration, and sleep disorders were included in study. A Chi-Square test were used to examine the association between smoking duration, sleep disorders, and nutritional status in men aged 26 – 45 years. Results: Based on the results of statistical tests conducted, it was found that the majority of respondents had a smoking duration of 11-20 years, where as many as 1463 respondents did not experience sleep disorders and 1365 had sleep disorders. The nutritional status of respondents with smoking duration of 11-20 years is normal as many as 1882 respondents and at least 27 respondents have underweight nutritional status with smoking duration <5 years. Furthermore, the test results of the relationship between smoking duration and sleep disturbances obtained p-value = 0.03 and the relationship between smoking duration and nutritional status obtained p-value <0.01. Conclusion: Smoking duration was associated with the incidence of sleep disorder and nutritional status in men aged 26 – 45 years.
  PubDate: Thu, 16 Dec 2021 07:31:51 SE A
Spatial Variation of Tuberculosis Risk in Indonesia 2010-2019
- Authors: Tities Puspita; Anton Suryatma, Oster Suriani Simarmata, Ginoga Veridona, Heny Lestary, Athena Athena, Imran Pambudi, Sulistyo Sulistyo, Tiffany Tiara Pakasi
  Abstract: Abstract Background: As the second highest country in tuberculosis (TB) cases globally, Indonesia has experienced an increasing trend of notification rate in the last ten years; however, the 34 provinces may have different risks. This study aims to examine TB risk variation across Indonesia in 2010-2019. Methods: A descriptive analysis was conducted on TB routine data of 2010-2019 from the Ministry of Health. Cases included all types of TB patients. Total cases, incidence rate (IR), and standardized morbidity ratio (SMR) were calculated for each province and national level during the period. Distributions of IRs and SMRs were displayed on maps. Results: During 2010-2019, 3,866,447 TB cases occurred in Indonesia, and the national IR was 1,523 per 100,000 populations. The highest proportion of cases and IR were in West Java (20.6%, 314 per 100,000); while the lowest were in North Kalimantan (0.2%, 3 per 100,000). Higher risks of TB occurred in DKI Jakarta (SMR 1.9), Papua (1.7), North Sulawesi (1.7), Maluku (1.5) and West Papua (1.5) among others. The smallest SMRs were found in Bali and Yogyakarta (0.5). Conclusion: TB risk varied across Indonesia in 2010-2019, with higher risk in DKI Jakarta and several provinces in eastern Indonesia. Given the underreporting nature of routine data, a validation is required when using the finding of this study in the local-level intervention. Keywords: tuberculosis, TB, standardized morbidity ratio, spatial variation, risk Abstrak Latar belakang: Sebagai negara dengan jumlah kasus tuberkulosis (TB) terbesar kedua di dunia, Indonesia menunjukkan tren peningkatan notification rate di sepuluh tahun terakhir. Akan tetapi, risiko TB di 34 provinsi bisa saja berbeda-beda. Artikel ini bertujuan mengkaji variasi risiko TB di Indonesia pada tahun 2010-2019. Metode: Data rutin TB tahun 2010-2019 dari Kementerian Kesehatan dianalisis secara deskriptif. Kasus TB didefinisikan sebagai semua tipe pasien TB. Total jumlah kasus, incidence rate (IR), dan standardized morbidity ratio (SMR) dihitung untuk tiap provinsi dan tingkat nasional selama periode tersebut. Sebaran IR dan SMR diplot di atas peta. Hasil: Selama 2010-2019, terdapat 3.866.447 kasus TB dan IR nasional 1.523 per 100.000 populasi. Proporsi kasus dan IR terbesar ada di Jawa Barat (20,6%, 314 per 100.000) dan terkecil di Kalimantan Utara (0,2%, 3 per 100.000). Risiko TB lebih tinggi di antaranya terjadi di DKI Jakarta (SMR 1,9), Papua (1,7), Sulawesi Utara (1,7), Maluku (1,5) dan Papua Barat (1,5). SMR terendah ditemukan di Bali dan Yogyakarta (0,5). Kesimpulan: Dapat disimpulkan bahwa risiko TB beragam di seluruh Indonesia selama 2010-2019, di mana DKI Jakarta dan beberapa provinsi di timur Indonesia memiliki risiko lebih tinggi. Mengingat adanya kurang lapor dalam data rutin, validasi diperlukan jika menggunakan temuan studi ini dalam intervensi di tingkat lokal. Kata kunci: tuberkulosis, TB, standardized morbidity ratio, variasi spasial, risiko
  PubDate: Thu, 16 Dec 2021 07:28:27 SE A
Factors Associated with Measles Antibody Titers in Children Aged 12-36
Months in Indonesia
- Authors: Ni Ketut Ketut Aryastami; Prisca Petty Arfines, Vivi Setyawaty, Siti Isfandari
  Abstract: Background: The immunization program in Indonesia has been implemented since 1956 started with Mump immunization. The purpose of this paper is to study the child's Measles antibody titer as the outcome of completed basic vaccination and its contributors to children aged 12-36 months. Methods: This study is a secondary data analysis of the Indonesia Basic Health Survey (RISKESDAS) 2013. The analysis was carried out on a serological sample of the antibody titer of children aged 12-36 months, totaling 229 samples. Results: Incomplete immunization, being a boy, and lack of cleanliness in the family room were significantly associated with lower measles antibody levels in children. Having each variable controlled, completeness of immunization (OR=1,99; p=0.018; 95% CI=1.124-3.544) and gender of boy (OR=2.0; p=0.016; 95% CI=1.137-3.515) remain as significant variables for antibody’s titer. Conclusion: The completeness of immunization has a significant association towards titer antibody of Measles in children. Immunization completeness is an actual effort to prevent herd immunity in children and a measles outbreak in the community. Adequate health promotion is needed to change people's behavior to believe in the safety and importance of implementing complete basic immunization for children even in pandemic conditions.
  PubDate: Thu, 16 Dec 2021 07:22:07 SE A
Priority Setting in Responding COVID-19 Pandemic: A Hospital
Leaders’ Perspective
- Authors: Aryo Dewanto; Yudi Setyawan, Viera Wardhani
  Abstract: Background: The COVID-19 pandemic hit Indonesia when hospitals were striving to adjust to a changing environment after a new health insurance system implementation, a government’s effort to achieve Universal Health Coverage. As a result, the pandemic forced hospitals to exploit their resources. Due to limited resources, setting accurate priorities is highly important to secure hospital operations and maintain its track towards the expected goals. This study aims to explore how deep the pandemic impacts hospitals and how hospital leaders in Indonesia set their priorities in responding to the impact of this pandemic. Methods: This study used a descriptive and analytical approach. Data were collected through an online survey from hospital leaders and several documentary sources. Results: The results show that almost all hospital directors consider patient visits and hospital finance the most significant impacts of the COVID-19 pandemic. However, government hospital directors emphasize different areas compared to non-government hospital directors; the former sets their priorities on the hospital’s human resources, quality of service, and operations, while the latter focuses on the impact of patient visits and hospital finance. Conclusion: Although directors of government and non-governmental hospitals have a different emphasis, their priority is the same, maintaining hospital sustainability to provide quality services to people.
  PubDate: Thu, 16 Dec 2021 07:08:40 SE A
The Analysis of The Timeliness of Laboratory Critical Value Reporting
Before and After Accreditation in Hospital X
- Authors: Wahyu Febrianto; Menis Rahmawati, I Gede Sastrawan, Tita Hariyanti
  Abstract: Background: Patient safety is the main issue on healthcare service nowadays. Delaying to inform critical value of laboratory result is a significant source of harm for the patient. The aim of this study is to reveal correlation between accreditation and the timeliness of laboratory critical value reporting as one of service quality indicator in Hospital X. Methods: This study was done by using observational cross-sectional with total sampling method of 816 data of critical value reporting to responsible clinician that originated from Intensive Care Unit(ICU), Verlos Kamer(VK), and inpatient ward (IW) 1-6. The timeliness of reporting was counted since the laboratory result obtained until received by responsible clinician within £30 minutes and categorized as "On time" or "Late". Results: During 2019, there were 816 reporting which has been done before accreditation (511) and after accreditation (305) with 17 kind of tests. The most reported test was platelet with 349 (before accreditation) and 101 (after accreditation), whilst SGOT/SGPT and albumin was the fewest one. The lowest timeliness of reporting percentage was 76,00% (February), whilst the highest was 98,48% (November). The timeliness of reporting's percentage was 84,34% (before accreditation) and 94,43% (after accreditation). The statistical analysis result revealed Pearson Chi-Square correlation was 18,535 with a significance 0,000. Conclusion: This result showed that accreditation could affect the timeliness of laboratory critical value reporting to responsible clinician. Keywords: Accreditation, Critical Value, Laboratory, Patient Safety, Hospital.
  PubDate: Thu, 16 Dec 2021 06:59:57 SE A
Interferon Gamma Concentration in Diabetes Mellitus and Dyslipidemia
Patient
- Authors: Nelly Marissa; Merlinda Marlinda, Maulidar Maulidar, Veny Wilya, Nur Ramadhan, zain hadifah
  Abstract: ABSTRAK Pendahuluan: Penderita diabetes mellitus (DM) mengalami inflamasi kronik yang ditandai dengan perubahan konsentrasi berbagai sitokin. Penelitian ini bertujuan untuk memeriksa konsentrasi IFN-γ pada penderita DM dan dislipidemia. Metode: Sebanyak 234 orang yang terdiri dari 69 orang penderita DM dan 165 orang non DM. Dari setiap responden dilakukan pengambilan darah sebanyak 5 ml untuk dilakukan pemeriksaan kadar gula darah puasa (KGD P), trigliserida, high density lipoprotein (HDL), dan inrferon- gamma (IFN-γ). Pemeriksaan KGD, trigliserida, HDL dilakukan dengan metode enzimatik kolorimetrik. Pemeriksaan konsentrasi protein IFN-γ menggunakan teknik sandwich Enzyme-linked immunosorbent assay (ELISA). Hasil: Konsentrasi IFN-γ pada kelompok non-DM lebih tinggi dibandingkan dengan kelompok DM. Terdapat perbedaan bermakna antara rata-rata konsentrasi IFN-γ pada kelompok non-DM dibandingkan dengan kelompok DM (p=0,000). Pada kelompok KGD <126 mg/dl memiliki konsentrasi IFN-γ yang lebih tinggi dibandingkan dengan kelompok dengan kadar glukosa darah puasa ≥126 mg/dl. Terdapat perbedaan bermakna perbedaan konsentrasi IFN-γ antar kedua kelompok tersebut (p=0,000). Kelompok dengan kadar trigliserida <150 mg/dl memiliki kadar IFN-γ lebih rendah dibandingkan dengan kelompok dengan kadar trigliserida ≥ 150 mg/dl. Terdapat perbedaan bermakna antara rata-rata konsentrasi konsentrasi IFN-γ antar kedua kelompok tersebut (p=0,000). Kesimpulan: Terdapat perbedaan konsentrasi IFN-γ pada orang dengan DM dan dislipidemia. Kata kunci : IFN-γ, diabetes mellitus, dislipidemia. ABSTRACT Introduction: Patient with diabetes mellitus (DM) occurs chronic inflammation by characterized a decrease concentration of various cytokinin type. This study aimed to determine IFN-γ concentration in DM and dyslipidemia patients. Metode: An amount of 234 peoples consisted of 69 peoples diagnosed with diabetes mellitus and 165 peoples without diabetes mellitus. From each respondent, 5 ml of blood was taken to check fasting blood glucose, triglycerides, high density lipoproteins (HDL), and interferon-gamma (IFN-γ). Test of fasting blood glucose, triglycerides, HDL was carried out using the colorimetric enzymatic method. The IFN-γ protein concentration was examined using the sandwich enzyme-linked immunosorbent assay (ELISA) technique. Result: IFN-γ concentration in the non-DM group was higher than the DM group. There was a significant difference between the average IFN-γ concentration in the non-DM group compared with the DM group (p = 0.000). The fasting blood glucose group <126 mg/dl had a higher IFN-γ concentration than the group with fasting blood glucose levels ≥126 mg/dl. There was a significant difference in the concentration of IFN-γ between the two groups (p = 0.000). The group with triglyceride levels <150 mg/dl had lower IFN-γ levels than the group with triglyceride levels ≥ 150 mg/dl. There was a significant difference between the average IFN-γ concentration between those groups (p = 0.000). Conclusion: There are differences in IFN-γ concentrations with DM and dyslipidemia patients. Keywords: IFN-γ, diabetes mellitus, dyslipidemia
  PubDate: Thu, 16 Dec 2021 05:45:23 SE A
Optimization of multiplex real-time RT-PCR for respiratory syncytial
viruses detection
- Authors: Agustiningsih Agustiningsih
  Abstract: Background: Multiplex real-time RT-PCR (rRT-PCR) is a fast, sensitive and specific test to detect more than one target in single PCR reaction. In this study we developed multiplex rRT-PCR for RSV-A and RSV-B since those viruses are the most common pathogen found in respiratory tract. However in order to gain optimal reaction for RSV-A and RSV-B detection, the optimization of primers and probes specific for RSV-A and RSV B are needed. Method: The primers and probes of multiplex rRT-PCR for RSV-A and RSV-B were selected and optimized utilizing PerlPrimer software and BLAST to analyze the secondary structures and specificity, respectively. Further testing of selected primers and probes for rRT-PCR was done using annealing temperature based on in silico analysis as mentioned above. This includes sensitivity testing with the utilization of synthesized DNA of RSV-A and RSV-B and specificity testing targeting the common viruses found in respiratory tract. Results: The primer set and probes selected for RSV-A and RSV-B detection were specific and showed no secondary structure. The multiplex rRT-PCR test using selected primers and probes was able to detect synthesized DNA of RSV-A and RSV-B. Conclusion: Multiplex rRT-PCR that employing primer sets and probes targeted N gene of RSV-A and RSV-B in this study were able to be detect RSV-A and RSV-B in single PCR reaction. Keyword: Multiplex, real-time RT-PCR, RSV-A, RSV-B Abstrak Latar Belakang: Multiplex real-time RT-PCR (rRT-PCR) merupakan metode yang cepat, sensitif dan specifik untuk mendeteksi lebih dari satu target pathogen dalam satu reaksi PCR. Panelitian ini bertujuan untuk mengembangkan multiplex rRT-PCR virus RSV-A dan RSV-B yang merupakan patogen yang paling sering ditemukan di saluran pernafasan. Optimisasi dari primer dan probe dalam multiplex rRT-PCR diperlukan untuk mendapatkan reaksi yang optimal dalam deteksi virus RSV-A dan RSV-B. Metode: Primer dan probe untuk multiplex rRT-PCR RSV-A dan RSV-B dipilih dan dioptimasi menggunakan software PerlPrimer dan BLAST untuk menganalisis adanya struktur sekunder serta spesifisitas dari primer dan probe. Uji multiplex rRT-PCR dilanjutkan berdasarkan suhu annealing berdasarkan hasil analisis menggunakan PerlPrimer. Uji senstitifitas dilakukan dengan menggunakan DNA sintetis dari RSV-A dan RSV-B dan uji spesifiitas dilakukan dengan mengetes primer dan probe terhadap virus-virus lain yang umumnya ditemukan di saluran pernafasan. Hasil: Primer dan probe yang dikembangkan pada penelitian ini tidak membentuk struktur sekunder dan spesifik. Uji multiplex rRT-PCR yang dikembangkan pada penelitian ini mampu mendeteksi DNA sintetis RSV-A dan RSV-B Kesimpulan: Multiplex rRT-PCR dengan menggunakan primer dan probe untuk RSV-A dan RSV-B dapat mendeteksi RSV-A dan RSV-B dalam satu reaksi PCR. Kata kunci: multiplex, real-time RT-PCR, RSV-A, RSV-B
  PubDate: Thu, 16 Dec 2021 05:38:21 SE A