Publisher: American Society for Microbiology
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Antimicrobial Agents and Chemotherapy
Journal Prestige (SJR): 2.291 ![]() Citation Impact (citeScore): 4 Number of Followers: 27 ![]() ISSN (Print) 0066-4804 - ISSN (Online) 1098-6596 Published by American Society for Microbiology ![]() |
- Pharmacodynamics of Temocillin in Neutropenic Murine Infection Models
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Authors: Anouk E. Muller; Merel Raaphorst, Aart van der Meijden, Brenda C. M. de Winter, Joseph Meletiadis, Sanne van den Berg aDepartment of Medical Microbiology Kapodistrian University of Athens, Athens, Greece
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-24T08:00:00Z
DOI: 10.1128/aac.01433-22
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- Serine/Threonine Phosphatase Calcineurin Orchestrates the Intrinsic
Resistance to Micafungin in the Human-Pathogenic Fungus Mucor
circinelloides-
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Authors: Alexis Garcia; Eun Young Huh, Soo Chan Lee aSouth Texas Center for Emerging Infectious Diseases (STCEID), Department of Molecular Microbiology Disease Department, San Antonio, Texas, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-23T08:00:00Z
DOI: 10.1128/aac.00686-22
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- The 4-Aminomethylphenoxy-Benzoxaborole AN3057 as a Potential Treatment
Option for Primary Amoebic Meningoencephalitis-
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Authors: Kateřina Ženíšková; Jan Mach, Dominik Arbon, Jan Štursa, Lukáš Werner, Martin Zoltner, Robert Sutak aDepartment of Parasitology, Faculty of Science, Charles University, BIOCEV, Vestec, Czech Republic bInstitute of Biotechnology, Czech Academy of Sciences, BIOCEV, Vestec, Czech Republic
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-23T08:00:00Z
DOI: 10.1128/aac.01506-22
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- Activity of Oral Tebipenem-Avibactam in a Mouse Model of Mycobacterium
abscessus Lung Infection-
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Authors: Dereje A. Negatu; Rubén González del Río, Mónica Cacho-Izquierdo, David Barros-Aguirre, Joël Lelievre, Joaquín Rullas, Patricia Casado, Uday S. Ganapathy, Matthew D. Zimmerman, Martin Gengenbacher, Véronique Dartois, Thomas Dick aCenter for Discovery Immunology, Georgetown University, Washington, DC, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-23T08:00:00Z
DOI: 10.1128/aac.01459-22
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- Correction for Antachopoulos et al., “Population Pharmacokinetics and
Outcomes of Critically Ill Pediatric Patients Treated with Intravenous
Colistin at Higher than Recommended Doses”-
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Authors: Charalampos Antachopoulos; Anastasia Geladari, Cornelia B. Landersdorfer, Eleni Volakli, Stavroula Ilia, Evangelos Gikas, Helen Gika, Maria Sdougka, Roger L. Nation, Emmanuel Roilides
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-19T08:00:00Z
DOI: 10.1128/aac.01685-22
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- Frequent Transmission of Streptococcus pneumoniae Serotype 35B and 35D,
Clonal Complex 558 Lineage, across Continents and the Formation of
Multiple Clades in Japan-
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Authors: Koh Shinohara; Takao Fujisawa, Bin Chang, Yutaka Ito, Shigeru Suga, Yasufumi Matsumura, Masaki Yamamoto, Miki Nagao, Makoto Ohnishi, Motoyuki Sugai, Satoshi Nakano aDepartment of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan bNational Hospital Organization Mie National Hospital, Tsu, Japan cBacteriology I, National Institute of Infectious Diseases, Tokyo, Japan dNagoya City University, Graduate School of Medical Science, Nagoya, Japan eAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-18T08:00:00Z
DOI: 10.1128/aac.01083-22
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- Structural and Biochemical Features of OXA-517: a Carbapenem and
Expanded-Spectrum Cephalosporin Hydrolyzing OXA-48 Variant-
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Authors: Laura Dabos; Joanna E. Raczynska, Pierre Bogaerts, Agustin Zavala, Delphine Girlich, Remy A. Bonnin, Laurent Dortet, Aurélie Peyrat, Pascal Retailleau, Bogdan I. Iorga, Mariusz Jaskólski, Youri Glupczynski, Thierry Naas aTeam “Resist” UMR1184, INSERM, CEA, University Paris-Saclay, LabEx LERMIT, Faculty of Medicine, Le Kremlin-Bicêtre, France bFrench National Reference Center for Antibiotic Resistance: Carbapenemase-producing Enterobacterales, Le Kremlin-Bicêtre, France cCenter for Biocrystallographic Research, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland dDepartment of Bacteriology-Hygiene, Bicêtre Hospital, APHP Paris-Saclay, Le Kremlin-Bicêtre, France eLaboratory of Clinical Microbiology, National Reference Center for Monitoring Antimicrobial Resistance in Gram-Negative Bacteria, CHU UCL Namur, Yvoir, Belgium fUniversité Paris-Saclay, CNRS UPR 2301, Institut de Chimie des Substances Naturelles, Labex LERMIT, Gif-sur-Yvette, France gDepartment of Crystallography, Faculty of Chemistry, A. Mickiewicz University, Poznan, Poland
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-17T08:00:00Z
DOI: 10.1128/aac.01095-22
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- Clofazimine Inhalation Suspension Demonstrates Promising Toxicokinetics in
Canines for Treating Pulmonary Nontuberculous Mycobacteria Infection-
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Authors: M. Kunkel; M. Doyle-Eisele, P. Kuehl, K. Rotermund, M. Hittinger, S. Ufer, M. Reed, M. Grant, T. Hofmann aMarkAllen Consulting LLC, Lawrenceville, New Jersey, USA bLovelace Biomedical, Albuquerque, New Mexico, USA cPharmBioTec Research Development GmbH, Saarbrücken, Germany dSwabian Tech LLC, Raleigh, North Carolina, USA eCOELUS LLC, Albuquerque, New Mexico, USA fMannKind Corporation, Danbury, Connecticut, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-17T08:00:00Z
DOI: 10.1128/aac.01144-22
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- Impact of Vancomycin Loading Doses and Dose Escalation on Glomerular
Function and Kidney Injury Biomarkers in a Translational Rat Model-
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Authors: Jack Chang; Gwendolyn M. Pais, Patti L. Engel, Patryk Klimek, Sylwia Marianski, Kimberly Valdez, Marc H. Scheetz aMidwestern University College of Pharmacy, Department of Pharmacy Practice, Downers Grove, Illinois, USA bMidwestern University College of Pharmacy, Pharmacometrics Center of Excellence, Downers Grove, Illinois, USA cNorthwestern Memorial Hospital, Department of Pharmacy, Chicago, Illinois, USA dMidwestern University College of Graduate Studies, Department of Pharmacology, Downers Grove, Illinois, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-17T08:00:00Z
DOI: 10.1128/aac.01276-22
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- Erratum for Wiederhold et al., “The Antifungal and Anti-Pneumocystis
Activities of the Novel Compound A3IS (Mycosinate)”-
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Authors: Nathan P. Wiederhold; Thomas F. Patterson, Sandra Rebholz, James Brennan, Thomas Patton, John Barrett, Connell W. C. Boal, Monika Ehrensberger, Ryan Boyle, Melanie T. Cushion aDepartment of Pathology Laboratory Medicine, University of Texas Health Science Center, San Antonio, Texas, USA bDepartment of Medicine, University of Texas Health Science Center, San Antonio, Texas, USA cSouth Texas Veterans Health Care System, San Antonio, Texas, USA dDepartment of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA eMedical Research Service, Cincinnati Veterans Affairs Medical Center, Cincinnati, Ohio, USA fNektr Technologies Ltd., Sligo, Ireland gAtlantic Technological University Sligo, Sligo, Ireland
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-16T08:00:00Z
DOI: 10.1128/aac.01475-22
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- A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles
of PfMDR1 and PfCRT in Parasite Drug Responses-
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Authors: Brajesh K. Singh; Cui Zhang, Jian Wu, Yu-Chih Peng, Xiao He, Keyla C. Tumas, Juliana M. Sá, Kristin D. Lane, Richard T. Eastman, David L. Narum, Thomas E. Wellems, Xin-zhuan Su aLaboratory of Malaria Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-10T08:00:00Z
DOI: 10.1128/aac.00821-22
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- High-Resolution Bacterial Cytological Profiling Reveals Intrapopulation
Morphological Variations upon Antibiotic Exposure-
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Authors: Thanadon Samernate; Htut Htut Htoo, Joseph Sugie, Warinthorn Chavasiri, Joe Pogliano, Vorrapon Chaikeeratisak, Poochit Nonejuie aInstitute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand bDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA cCenter of Excellence in Natural Products Chemistry, Department of Chemistry, Chulalongkorn University, Bangkok, Thailand dDepartment of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-10T08:00:00Z
DOI: 10.1128/aac.01307-22
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- High Isoniazid Exposures When Administered with Rifapentine Once Weekly
for Latent Tuberculosis in Individuals with Human Immunodeficiency Virus-
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Authors: Ryan T. Jarrett; Yuri van der Heijden, Matthew S. Shotwell, Violet Chihota, Mark A. Marzinke, Richard E. Chaisson, Kelly E. Dooley, Gavin J. Churchyard aInstitute for Global Health, Vanderbilt University School of Medicine, Nashville, Tennessee, USA bDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA cVanderbilt Tuberculosis Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA dThe Aurum Institute, Johannesburg, South Africa eDepartment of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA fDepartments of Pathology Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA iSchool of Public Health, University of Witwatersrand, Johannesburg, South Africa
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-09T08:00:00Z
DOI: 10.1128/aac.01297-22
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- Efficacy of Replacing Linezolid with OTB-658 in Anti-Tuberculosis Regimens
in Murine Models-
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Authors: Haiting Liu; Hui Zhu, Lei Fu, Weiyan Zhang, Xi Chen, Bin Wang, Shaochen Guo, Yangming Ding, Ning Wang, Dongshuo Li, Yu Lu aDepartment of Pharmacology, Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis Thoracic Tumor Research Institute, Beijing, People’s Republic of China
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-09T08:00:00Z
DOI: 10.1128/aac.01399-22
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- Evaluation of Empirical Dosing Regimens for Meropenem in Intensive Care
Unit Patients Using Population Pharmacokinetic Modeling and Target
Attainment Analysis-
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Authors: Guohua An; C. Buddy Creech, Nan Wu, Roger L. Nation, Kenan Gu, Demet Nalbant, Natalia Jimenez-Truque, William Fissell, Stephanie Rolsma, Pratish C. Patel, Amy Watanabe, Nicholas Fishbane, Carl M. J. Kirkpatrick, Cornelia B. Landersdorfer, Patricia Winokur aDepartment of Pharmaceutical Sciences Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee, USA fDepartment of Pharmaceutical Services, Vanderbilt University Medical Center, Nashville, Tennessee, USA gThe Emmes Company, LLC, Rockville, Maryland, USA hDivision of Infectious Diseases, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-09T08:00:00Z
DOI: 10.1128/aac.01312-22
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- Population Pharmacokinetics and Dosage Optimization of Vancomycin in
Pediatric Patients with Skin and Soft Tissue Infections, Bone, and Joint
Infections-
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Authors: Meng Lv; Ping Yang, Shengnan Zhang, Lingling Wang, Keming Sun, Libo Zhao aDepartment of Pharmacy, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China bDepartment of Pharmacy, Peking University Third Hospital, Beijing, China cTherapeutic Drug Monitoring Clinical Toxicology Center, Peking University, Beijing, China dDepartment of Orthopaedic Surgery, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-09T08:00:00Z
DOI: 10.1128/aac.01624-22
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- Standardized RS Ratio Metrics To Assess Tuberculosis Antimicrobial
Efficacy and Potency-
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Authors: Matthew J. Reichlen; Sarah E. M. Born, Michael A. Lyons, Karen Rossmassler, Justin Reid, Gregory T. Robertson, Nicholas D. Walter, Martin I. Voskuil aDepartment of Immunology Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA eConsortium for Applied Microbial Metrics, Aurora, Colorado, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-09T08:00:00Z
DOI: 10.1128/aac.01483-22
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- Atypical Mutational Spectrum of SARS-CoV-2 Replicating in the Presence of
Ribavirin-
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Authors: Pilar Somovilla; Carlos García-Crespo, Brenda Martínez-González, María Eugenia Soria, Ana Isabel de Ávila, Isabel Gallego, Pablo Mínguez, Antoni Durán-Pastor, Cristina Ferrer-Orta, Llanos Salar-Vidal, Mario Esteban-Muñoz, Sonia Zuñiga, Isabel Sola, Luis Enjuanes, Jaime Esteban, Ricardo Fernandez-Roblas, Ignacio Gadea, Jordi Gómez, Nuria Verdaguer, Esteban Domingo, Celia Perales aCentro de Biología Molecular “Severo Ochoa” (CSIC-UAM), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain bDepartamento de Biología Molecular, Universidad Autónoma de Madrid, Madrid, Spain cCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain dDepartment of Molecular Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain eDepartment of Clinical Microbiology, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain fDepartment of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain gCentre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain hBioinformatics Unit, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain iStructural Biology Department, Institut de Biología Molecular de Barcelona CSIC, Barcelona, Spain jCIBERINFEC-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain kInstituto de Parasitología y Biomedicina ‘López-Neyra’ (CSIC), Parque Tecnológico Ciencias de la Salud, Armilla, Granada, Spain
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.01315-22
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- Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and
CTX-M β-Lactamases: Biochemical and Structural Analyses-
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Authors: Tahani A. Alsenani; María Margarita Rodríguez, Barbara Ghiglione, Magdalena A. Taracila, Maria F. Mojica, Laura J. Rojas, Andrea M. Hujer, Gabriel Gutkind, Christopher R. Bethel, Philip N. Rather, Maria Luisa Introvigne, Fabio Prati, Emilia Caselli, Pablo Power, Focco van den Akker, Robert A. Bonomo aDepartment of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA bUniversidad de Buenos Aires, Facultad de Farmacia y Bioquimica, Instituto de Investigaciones en Bacteriologia y Virologia Molecular, Buenos Aires, Argentina cConsejo Nacional de Investigaciones Científicas y Tecnicas, Buenos Aires, Argentina dDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA eLouis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA fDepartment of Molecular Biology Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.00930-22
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- Pharmacological Profiling of a Brugia malayi Muscarinic Acetylcholine
Receptor as a Putative Antiparasitic Target-
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Authors: Kendra J. Gallo; Nicolas J. Wheeler, Abdifatah M. Elmi, Paul M. Airs, Mostafa Zamanian aDepartment of Pathobiological Sciences, University of Wisconsin—Madison, Madison, Wisconsin, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.01188-22
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- Cyclic AMP-Mediated Inhibition of Cholesterol Catabolism in Mycobacterium
tuberculosis by the Novel Drug Candidate GSK2556286-
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Authors: Kirstin L. Brown; Kaley M. Wilburn, Christine R. Montague, Jason C. Grigg, Olalla Sanz, Esther Pérez-Herrán, David Barros, Lluís Ballell, Brian C. VanderVen, Lindsay D. Eltis aMicrobiology Immunology, Cornell University, Ithaca, New York, USA cDiseases of the Developing World, GlaxoSmithKline R1D, Ltd., Tres Cantos, Madrid, Spain
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.01294-22
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- Molecular Characteristics of an NDM-4 and OXA-181 Co-Producing K51-ST16
Carbapenem-Resistant Klebsiella pneumoniae: Study of Its Potential
Dissemination Mediated by Conjugative Plasmids and Insertion Sequences-
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Authors: Feilong Zhang; Ziyao Li, Xinmeng Liu, Guolan Luo, Yongli Wu, Chen Li, Jiankang Zhao, Yulin Zhang, Yanning Hu, Binghuai Lu aPeking University China-Japan Friendship School of Clinical Medicine, Beijing, China bLaboratory of Clinical Microbiology Critical Care Medicine, National Center for Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China cInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China dChina-Japan Friendship Institute of Clinical Medical Sciences, Beijing, China eDepartment of Laboratory Medicine, Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, China fPeking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China gLiuyang Traditional Chinese Medicine Hospital, Changsha, Hunan, China
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.01354-22
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- Targeting Multidrug-Recalcitrant Pseudomonas aeruginosa Biofilms:
Combined-Enzyme Treatment Enhances Antibiotic Efficacy-
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Authors: Yixin Zhang; Wei Wei, Huamei Wen, Zhongle Cheng, Zhongwen Mi, Jing Zhang, Xiaolong Liu, Xinjiong Fan aSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China bThe First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China cUniversity of Science College, Key Laboratory of Oral Diseases Research of Anhui Province, Anhui Medical University, Hefei, Anhui, China
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.01358-22
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- In Vivo Effectiveness of Several Antimicrobial Locks To Eradicate
Intravascular Catheter Coagulase-Negative Staphylococci Biofilms-
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Authors: Andrés Blanco-Di Matteo; Nuria Garcia-Fernandez, Aitziber Aguinaga Pérez, Francisco Carmona-Torre, Amaya C. Oteiza, José Leiva, José Luis Del Pozo aInfectious Diseases Division, Clinica Universidad de Navarra, Pamplona, Spain bNephrology Department, Clinica Universidad de Navarra, Pamplona, Spain cClinical Microbiology Department, Hospital Universitario de Navarra, Pamplona, Spain dClinical Microbiology Department, Clínica Universidad de Navarra, Pamplona, Spain eNavarra Health Research Institute-IdiSNA, Pamplona, Spain
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.01264-22
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- Repurposing Carbamazepine To Treat Gonococcal Infection in Women: Oral
Delivery for Control of Epilepsy Generates Therapeutically Effective
Levels in Vaginal Secretions-
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Authors: Lucy K. Shewell; Christopher J. Day, Xavier De Bisscop, Jennifer L. Edwards, Michael P. Jennings aInstitute for Glycomics, Griffith University, Gold Coast, Queensland, Australia bThe Center for Microbial Pathogenesis, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA cThe Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.00968-22
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- In Vitro Activity of Ceftibuten-Avibactam against β-Lactamase-Positive
Enterobacterales from the ATLAS Global Surveillance Program-
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Authors: James A. Karlowsky; Meredith A. Hackel, Gregory G. Stone, Daniel F. Sahm aIHMA, Schaumburg, Illinois, USA bDepartment of Medical Microbiology Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada cPfizer Inc., Groton, Connecticut, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.01346-22
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- Erratum for Banda et al., “Impact of Dolutegravir-Based Antiretroviral
Therapy on Piperaquine Exposure following Dihydroartemisinin-Piperaquine
Intermittent Preventive Treatment of Malaria in Pregnant Women Living with
HIV”-
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Authors: Clifford G. Banda; Dumisile Nkosi, Elizabeth Allen, Lesley Workman, Mwayiwawo Madanitsa, Marumbo Chirwa, Mayamiko Kapulula, Sharon Muyaya, Steven Munharo, Joel Tarning, Kamija S. Phiri, Victor Mwapasa, Feiko O. ter Kuile, Gary Maartens, Karen I. Barnes
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-05T08:00:00Z
DOI: 10.1128/aac.01562-22
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- Going Back in Time: Increasing Penicillin Susceptibility among
Methicillin-Susceptible Staphylococcus aureus Osteoarticular Infections in
Children-
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Authors: J. Chase McNeil; Lauren M. Sommer, Jesus G. Vallejo, Mary Boyle, Kristina G. Hulten, Sheldon L. Kaplan, Stephanie A. Fritz aDepartment of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine, Houston, Texas, USA bTexas Children’s Hospital, Houston, Texas, USA cDepartment of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri, USA dSt. Louis Children’s Hospital, St. Louis, Missouri, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-04T08:00:00Z
DOI: 10.1128/aac.01196-22
-
- Erratum for Ranjbarian et al.,
“9-(2'-Deoxy-2'-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent
Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related
Drug Resistance”-
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Authors: Farahnaz Ranjbarian; Munender Vodnala, Khalid J. H. Alzahrani, Godwin U. Ebiloma, Harry P. de Koning, Anders Hofer
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2023-01-04T08:00:00Z
DOI: 10.1128/aac.01568-22
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- In Vitro Activity of Cefepime-Taniborbactam and Comparators against
Clinical Isolates of Gram-Negative Bacilli from 2018 to 2020: Results from
the Global Evaluation of Antimicrobial Resistance via Surveillance (GEARS)
Program-
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Authors: James A. Karlowsky; Meredith A. Hackel, Mark G. Wise, David A. Six, Tsuyoshi Uehara, Denis M. Daigle, Susan M. Cusick, Daniel C. Pevear, Greg Moeck, Daniel F. Sahm aIHMA, Schaumburg, Illinois, USA bDepartment of Medical Microbiology Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada cVenatorx Pharmaceuticals, Inc., Malvern, Pennsylvania, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-21T08:00:00Z
DOI: 10.1128/aac.01281-22
-
- Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in
Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida-
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Authors: Shelby R. Simar; Truc T. Tran, Kirsten B. Rydell, Diana Panesso, German A. Contreras, Jose M. Munita, Renzo O. Cifuentes, Lilian M. Abbo, Pranoti Sahasrabhojane, An Q. Dinh, Dierdre B. Axell-House, Tor Savidge, Samuel A. Shelburne, Blake M. Hanson, Cesar A. Arias aCenter for Infectious Diseases, University of Texas Health Science Center, School of Public Health, Houston, Texas, USA bDivision of Infectious Diseases, Houston Methodist Hospital, Houston, Texas, USA cCenter for Infectious Diseases, Houston Methodist Research Institute, Houston, Texas, USA dMolecular Genetics Resistant Microbes (GeRM) Group, Facultad de Medicina Clínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile gMillennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R), Santiago, Chile hJackson Health System, Miami Transplant Institute, Miami, Florida, USA iDepartment of Infectious Diseases, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA jTexas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas, USA kDepartment of Medicine, Weill Cornell Medical College, New York, New York, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-21T08:00:00Z
DOI: 10.1128/aac.01284-22
-
- Neutralization of Staphylococcus aureus Protein A Prevents Exacerbated
Osteoclast Activity and Bone Loss during Osteomyelitis-
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Authors: Ana-Katharina E. Gehrke; Andrea Mendoza-Bertelli, Camila Ledo, Cintia D. Gonzalez, Mariángeles Noto Llana, Cintia Blanco, Daniel O. Sordelli, Nicole E. Putman, James E. Cassat, María Victoria Delpino, Marisa I. Gómez aCentro de Estudios Biomédicos, Básicos, Aplicados y Desarrollo (CEBBAD), Departamento de Investigaciones Biomédicas y Biotecnológicas, Universidad Maimónides, Buenos Aires, Argentina bConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina cInstituto de investigaciones en Microbiología y Parasitología Médica (IMPaM), Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de Buenos Aires, Buenos Aires, Argentina dDepartamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina eDepartment of Pathology, Microbiology, Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA fDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA gInstituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de Buenos Aires, Buenos Aires, Argentina hDepartment of Biomedical Engineering, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-19T08:00:00Z
DOI: 10.1128/aac.01140-22
-
- Validation and Application of Long-Read Whole-Genome Sequencing for
Antimicrobial Resistance Gene Detection and Antimicrobial Susceptibility
Testing-
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Authors: Thomas Weinmaier; Rick Conzemius, Yehudit Bergman, Shawna Lewis, Emily B. Jacobs, Pranita D. Tamma, Arne Materna, Johannes Weinberger, Stephan Beisken, Patricia J. Simner aAres Genetics GmbH, Vienna, Austria bDepartment of Pathology, Johns Hopkins University School of Medicinegrid.471401.7, Baltimore, Maryland, USA cDepartment of Pediatrics, Division of Infectious Diseases, Johns Hopkins University School of Medicinegrid.471401.7, Baltimore, Maryland, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-19T08:00:00Z
DOI: 10.1128/aac.01072-22
-
- Omadacycline Pharmacokinetics: Influence of Mortality Risk Score among
Patients with Community-Acquired Bacterial Pneumonia-
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Authors: M. Trang, J. P. Hammel, E. A. Lakota, M. C. Safir, S. M. Bhavnani, L. Friedrich, J. N. Steenbergen, P. C. McGovern, E. Tzanis, C. M. Rubino aInstitute for Clinical Pharmacodynamics, Inc; Schenectady, New York, USA bParatek Pharmaceuticals, Inc, King of Prussia, Pennsylvania, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-19T08:00:00Z
DOI: 10.1128/aac.02201-21
-
- Characterization of a Novel Capsid Assembly Modulator for the Treatment of
Chronic Hepatitis B Virus Infection-
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Authors: Dara Burdette, Anastasia Hyrina, Zhijuan Song, Rudolf K. Beran, Tara Cheung, Sarah Gilmore, Tetsuya Kobayashi, Li Li, Yang Liu, Anita Niedziela-Majka, Jonathan Medley, Upasana Mehra, Philip Morganelli, Nikolai Novikov, Congrong Niu, Danny Tam, Jennifer Tang, Jianhong Wang, Qin Yue, Simon P. Fletcher, Meghan M. Holdorf, William E. Delaney, Becket Feierbach, Scott Lazerwith aGilead Sciences, Inc; Foster City, California, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-15T08:00:00Z
DOI: 10.1128/aac.01348-22
-
- Prophylactic Administration of the Monoclonal Antibody Adintrevimab
Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of
COVID-19-
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Authors: Elizabeth E. Zumbrun, Chengzi I. Kaku, Lukas Dillinger, Samantha E. Zak, Ana I. Kuehne, Russel R. Bakken, Jeffrey W. Koehler, Korey L. Delp, Christopher P. Stefan, Raina Kumar, Jeffrey R. Kugelman, Alicia M. Moreau, Xiankun Zeng, John M. Dye, Andrew S. Herbert, Kristin Narayan, Laura M. Walker aU.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA bAdimab LLC, Lebanon, New Hampshire, USA cInvivyd, Inc; Waltham, Massachusetts, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-15T08:00:00Z
DOI: 10.1128/aac.01353-22
-
- A Double-Blind, Randomized, Placebo-Controlled, Phase II Clinical Study To
Evaluate the Efficacy and Safety of Camostat Mesylate (DWJ1248) in Adult
Patients with Mild to Moderate COVID-19-
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Authors: Yeon-Sook Kim; Seng-Ho Jeon, Junghee Kim, Jong Hoon Koh, Seung Won Ra, Ji Won Kim, Yeonjae Kim, Choon Kwan Kim, Yun Chul Shin, Beo Deul Kang, Seung ji Kang, Chul Hee Park, Boyoung Lee, Ji Yeon Lee, Chung Hoon Lee, Jae-phil Choi, Jin Yong Kim, Shi Nae Yu, Kyong Ran Peck, Sung-Han Kim, Jung Yeon Heo, Hyun ah Kim, Hyun-jin Park, JoungWon Choi, Jumi Han, JooHyun Kim, Hyoung jun Kim, Se Hee Han, Aeri Yoon, MiHee Park, SuJung Park, YuKyung Kim, Minji Jung, Myoung-don Oh aDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, South Korea bDaewoong Pharmaceutical Co., Ltd., Seoul, South Korea cDepartment of Neurosurgery, Seoul Medical Center, Seoul, South Korea dDepartment of Internal Medicine, Seonam Hospital, Seoul, South Korea eDepartment of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea fDepartment of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, South Korea gDivision of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, South Korea hDepartment of Internal Medicine, Veterans Health Service Medical Center, Seoul, South Korea iDepartment of Anesthesiology Gynecology, Gyeonggi Provincial Medical Center Suwon Hospital, Suwon, South Korea pDepartment of Internal Medicine, Seoul Medical Center, Seoul, South Korea qDepartment of Internal Medicine, Incheon Medical Center, Incheon, South Korea rDepartment of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, South Korea sDivision of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea tDepartment of Internal Medicine, Asan Medical Centergrid.413967.e, Seoul, South Korea uDepartment of Infectious Diseases, Ajou University School of Medicine, Suwon, South Korea vDepartment of Medicine, Division of Infectious Diseases, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea wClinical Development Center, Daewoong Pharmaceutical Co., Ltd., Seoul, South Korea xDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-14T08:00:00Z
DOI: 10.1128/aac.00452-22
-
- Safety, Tolerability, Pharmacokinetics, and Metabolism of Telacebec (Q203)
for the Treatment of Tuberculosis: a Randomized, Placebo-Controlled,
Multiple Ascending Dose Phase 1B Trial-
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Authors: Jeongjun Kim, Jinho Choi, Hwankyu Kang, Jiye Ahn, Jane Hutchings, Christo van Niekerk, Jaeseung Kim, Yeejin Jeon, Kiyean Nam, Tae Hwan Kim, Beom Soo Shin, Soyoung Shin aSchool of Pharmacy, Sungkyunkwan University, Suwon-si, Gyeonggi-do, South Korea bQurient Co; Ltd, Seongnam-si, Gyeonggi-do, South Korea cCollege of Pharmacy, Daegu Catholic University, Gyeongsan, Gyeongbuk, South Korea dCollege of Pharmacy, Wonkwang University, Iksan-si, Jeonbuk, South Korea
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-12T08:00:00Z
DOI: 10.1128/aac.01123-22
-
- Comparison of Pharmacokinetics of the GalNAc-Conjugated Antisense
Oligonucleotide GSK3389404 in Participants with Chronic Hepatitis B
Infection across the Asia-Pacific Region-
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Authors: Kelong Han, Hiroshi Ito, Robert Elston, Jennifer Cremer, Steve Hood, Melanie Paff, Dickens Theodore aGSK, Collegeville, Pennsylvania, USA bGSK K.K; Tokyo, Japan cGSK, Stevenage, United Kingdom dGSK, Durham, North Carolina, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-12T08:00:00Z
DOI: 10.1128/aac.00900-22
-
- Activity of ETX0462 toward Some Burkholderia spp.
-
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Authors: Elise T. Zeiser; Scott A. Becka, John J. LiPuma, Krisztina M. Papp-Wallace aResearch Service, VA Northeast Healthcare System, Cleveland, Ohio, USA bDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA cDepartment of Medicine, Case Western Reserve University, Cleveland, Ohio, USA dDepartment of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-12T08:00:00Z
DOI: 10.1128/aac.01352-22
-
- Penicillin Binding Protein 7/8 Is a Potential Drug Target in
Carbapenem-Resistant Acinetobacter baumannii-
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Authors: Thomas A. Russo; Ulrike Carlino-MacDonald, Cassandra L. Alvarado, Connor J. Davies, Oscar Barnes, Grishma Trivedi, Parijat Mathur, Alan Hutson, Felise G. Adams, Maoge Zang, Alice Ascari, Bart A. Eijkelkamp aVeterans Administration Western New York Healthcare System, Buffalo, New York, USA bDepartment of Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA cDepartment of Microbiology Biomedical Science, Research Centre for Infectious Diseases, University of Adelaide, Adelaide, South Australia, Australia
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-07T08:00:00Z
DOI: 10.1128/aac.01033-22
-
- Machine Learning To Stratify Methicillin-Resistant Staphylococcus aureus
Risk among Hospitalized Patients with Community-Acquired Pneumonia-
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Authors: Nathaniel J. Rhodes; Roxane Rohani, Paul R. Yarnold, Anna E. Pawlowski, Michael Malczynski, Chao Qi, Sarah H. Sutton, Teresa R. Zembower, Richard G. Wunderink aDepartment of Pharmacy Practice, Midwestern University, Chicago College of Pharmacy, Downers Grove, Illinois, USA bPharmacometrics Center of Excellence, Midwestern University, Downers Grove, Illinois, USA cDepartment of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois, USA dOptimal Data Analysis, LLC, Chicago, Illinois, USA eClinical Translational Sciences Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA fDepartment of Microbiology, Northwestern Memorial Hospital, Chicago, Illinois, USA gDepartment of Pathology, Northwestern Memorial Hospital, Chicago, Illinois, USA hDivision of Infectious Diseases, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA iHealthcare Epidemiology Critical Care Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-06T08:00:00Z
DOI: 10.1128/aac.01023-22
-
- In Vitro Activity of a Hypochlorous Acid-Generating Electrochemical
Bandage against Yeast Biofilms-
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Authors: Joseph Kletzer; Yash S. Raval, Abdelrhman Mohamed, Jayawant N. Mandrekar, Kerryl E. Greenwood-Quaintance, Haluk Beyenal, Robin Patel aParacelsus Medical University, Salzburg, Austria bDivision of Clinical Microbiology, Mayo Clinic, Rochester, Minnesota, USA cThe Gene Occupational Medicine, Mayo Clinic, Rochester, Minnesota, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-06T08:00:00Z
DOI: 10.1128/aac.01166-22
-
- Antimicrobial Susceptibility Testing Performed in RPMI 1640 Reveals
Azithromycin Efficacy against Carbapenem-Resistant Acinetobacter baumannii
and Predicts In Vivo Outcomes in Galleria mellonella-
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Authors: Sarah Miller; Kristine Goy, Rosemary She, Brad Spellberg, Brian Luna aDepartment of Molecular Microbiology Immunology, Keck School of Medicine at USC, Los Angeles, California, USA bDepartment of Pathology, Keck School of Medicine at USC, Los Angeles, California, USA cLos Angeles County-USC Medical Center, Los Angeles, California, USA
Abstract: Antimicrobial Agents and Chemotherapy, Ahead of Print.
Citation: Antimicrobial Agents and Chemotherapy
PubDate: 2022-12-05T08:00:00Z
DOI: 10.1128/aac.01320-22
-