Publisher: South Kazakhstan Medical Academy (Total: 1 journals)   [Sort by number of followers]

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Central Asian J. of Medical Hypotheses and Ethics     Open Access   (Followers: 1)
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Central Asian Journal of Medical Hypotheses and Ethics
Number of Followers: 1  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2708-9800
Published by South Kazakhstan Medical Academy Homepage  [1 journal]
  • DIFFERENCES IN BEHÇET’S DISEASE PHENOTYPE ACCORDING TO SEX: HYPOTHESES
           AND RESEARCH PERSPECTIVES

    • Authors: Hafize Emine Sönmez; Ezgi Deniz Batu
      Abstract: Behçet's disease (BD) is a multisystem vasculitis affecting both arteries and veins. Although the disease affects both sexes equally, males and females may express different phenotypes. The exact association between sex-related factors and BD phenotype is not clear, while many factors, such as genetic factors, hormones, and environmental and epigenetic factors may be the underlying factors of sex-related differences. This article summarizes the current literature focusing on the underlying factors determining differences in BD phenotype according to sex.
      PubDate: Mon, 14 Nov 2022 00:00:00 +020
       
  • ETHICS IN MEDICAL RESEARCH AND PUBLISHING

    • Authors: Hamid Ghaderi; Ehsan Shamsi Gooshki, Estie Kruger
      Abstract: This review aims to provide a concise argument on the importance of ethics in scientific endeavors. Consideration should be given to all aspects of a research project, including, study design, approval process, execution, and publication. In addition, parameters such as human roles in research and human rights are noted. Furthermore, critical questions such as confidentiality, beneficence, and non-maleficent research are emphasized. Apart from the significance of data analysis, the adverse consequences of unethical behaviors such as plagiarism, data falsification, and research bias are investigated.
      PubDate: Mon, 14 Nov 2022 00:00:00 +020
       
  • YOUTUBE AS A SOURCE OF INFORMATION ABOUT CORONAVIRUS DISEASE 2019 VACCINE

    • Authors: Erhan Kaya; Mikail Özdemir, Hüseyin Üçer, Burhan Fatih Koçyiğit
      Abstract: Introduction: YouTube is a very important source of information. The videos in YouTube provide a message with information. The purpose of this article was to assess the main message of available materials about coronavirus disease 2019 (COVID-19) vaccines on YouTube. Methods: In this study, the four search terms "COVID-19 vaccine", "COVID-19 vaccination", "Coronavirus vaccine", "Coronavirus vaccination" were scanned on the YouTube (www.youtube.com) media platform on 9 February 2021. We examined video parameters i.e., durations, view counts, likes, dislikes, comments, messages and sources of the 83 videos about COVID-19 vaccine. Results: The messages were defined as 52 (62.6%) positive, 12 (14.5%) negative, and 17 (20.5%) ambiguous about getting vaccinated. Significant differences were determined between the message category groups in respect of the like ratio (p = 0.014). Positive group videos were less liked. Conclusion: More negative messages about the COVID-19 vaccine were found in media-sourced videos. Negative and ambiguous videos were more attractive to YouTube users. Scientists, policymakers, and community leaders should play a role in disseminating information about COVID-19 vaccine and vaccination.
      PubDate: Mon, 14 Nov 2022 00:00:00 +020
       
  • DESIGN AND EVALUATION OF PSYCHOMETRIC ATTRIBUTES OF THE "PHYSICIANS'
           ATTITUDES TOWARD ESTABLISHING PERSONAL AND FRIENDLY COMMUNICATION WITH
           PATIENTS" SCALE

    • Authors: Fatemeh Hajibabaee; Atefeh Abdolkarimi, Mir Saeed Yekaninejad, Hadis Ashrafizadeh, Amirahmad Shojaei
      Abstract: The physician-patient communication is one of the most important forms of communication in the health system. If this communication loses its moral aspects for different reasons, it will lead to mistrust. Therefore, this research was conducted to design and evaluate the psychometric attributes of the "Physicians' attitudes toward establishing personal and friendly communication with patients" scale. The present methodological research was conducted in three phases. In the first phase, conventional content analysis was used. In the second phase, the terms of the questionnaire were developed using the results of the qualitative part. In the third stage, the psychometric attributes of the questionnaire were determined using face validity, content, and reliability of internal consistency and stability.  The score of all items of the questionnaire using the effective item selection method was more than 1.5. The CVR of 15 items was more than 0.62 and the CVI of all items was higher than 0.79. Cronbach's alpha of 0.749 was obtained to measure the internal consistency of the questionnaire using SPSS-v24 software. The used questionnaire has appropriate internal validity and reliability. Based on the results, there was no comprehensive and unified attitude towards establishing personal and friendly relations between a physician and a patient among experts.
      PubDate: Mon, 14 Nov 2022 00:00:00 +020
       
  • REVIEW: RESEARCH INTEREST SCORE IN RESEARCHGATE: THE SILVER BULLET OF
           SCIENTOMETRICS OR THE EMPEROR’S NEW CLOTHES'

    • Authors: Haris Memisevic
      Abstract: Introduction: Scientists have long searched for the best way to evaluate scientific performance and have come up with numerous indices. Probably, the most famous index is the h-index, a metric that has been used widely in science metrics ever since it appeared. In this study, I evaluated the potential of the new metric Research Interest Score created by ResearchGate (RG). Methods: I analyzed the different metric indices for 88 most cited researchers at the University of Sarajevo. In particular, the number of citations and h-indexes were taken from the Web of Science, Scopus, and Google Scholar databases for these researchers and were correlated with their Research Interest Scores. As a measure of correlation, Pearson correlation coefficients was used. In addition, I conducted a regression analysis to examine how scientometric indices from the Web of Science, Scopus, and Google Scholar predict the Research Interest Score.  Results: The Research Interest Score was most strongly correlated with the number of Google Scholar Citations, followed by the Web of Science citations.  Interestingly, the Research Interest Score was not highly correlated with any of the h-indexes. The regression model was statistically significant and explained 90% of the variance in the Research Interest Scores predicted by the Web of Science, Scopus, and Google Scholar metric indices. The strongest predictor of the Research Interest Score was the number of Google Scholar citations. Conclusions: The Research Interest Score, a new scientometric measure created by ResearchGate, certainly has a potential to be used as a valid measure of scientific impact.
      PubDate: Mon, 14 Nov 2022 00:00:00 +020
       
  • UNIVERSAL HUMAN-CENTERED HEALTH COVERAGE IN THE CENTRAL ASIAN REGION

    • Authors: Nurlan N. Brimkulov; Gulnara Zh. Kapanova, Sundetgali B. Kalmakhanov, Aidana R. Sagitova, Kurmanjan E. Bucaraeva
      Abstract: The article discusses the necessity to strengthen action to achieve universal health coverage (UHC), which has been slowed down by the COVID-19 pandemic, considering policy concepts. The dynamics of the UHC index in Kazakhstan and Kyrgyzstan for 2000-2019 is regarded. Several global activities for the development of primary health care and UHC in Kazakhstan are described, confirming the possibility of effective usage of political power to promote the ideas of primary health care, and this experience should be taken into account by other countries around the world.
      PubDate: Mon, 14 Nov 2022 00:00:00 +020
       
  • FROM HIPPOCRATIC OATH TO DECLARATION OF GENEVA: THE EVOLUTION OF ETHICAL
           VALUES IN MEDICAL PRACTICE

    • Authors: Abraham Edgar Gracia-Ramos
      Abstract: FROM HIPPOCRATIC OATH TO DECLARATION OF GENEVA: THE EVOLUTION OF ETHICAL VALUES IN MEDICAL PRACTICE
      PubDate: Mon, 14 Nov 2022 00:00:00 +020
       
  • MY LIFE AS A RESEARCHER, EDITOR AND MENTOR

    • Authors: Mohammad Abdollahi
      Abstract: MY LIFE AS A RESEARCHER, EDITOR AND MENTOR
      PubDate: Mon, 14 Nov 2022 00:00:00 +020
       
  • CONDUCTING RESEARCH: IS IT ROCKET SCIENCE'

    • Authors: Ilke Coskun Benlidayi
      Abstract: CONDUCTING RESEARCH: IS IT ROCKET SCIENCE'
      PubDate: Mon, 14 Nov 2022 00:00:00 +020
       
  • CAN PULMONARY SURFACTANT PROTEINS BE RELIABLE INDICATORS OF
           COVID-19-ASSOCIATED PULMONARY INJURY'

    • Authors: Yuliya Fedorchenko; Olena Zimba
      Abstract: The COVID-19 pandemic is still raging all over the world. New variants of the coronavirus emerge and infect recovered from previous infections, vaccinated, and unvaccinated subjects. One aspect remains unchanged that is the lungs are the main targets of the pandemic coronavirus. This challenging situation requires the search for reliable predictive markers of severe and complicated course of the disease. Serum surfactant proteins are known to correlate with pulmonary injury severity in numerous diseases. Measurement of such protein levels may help timely predict the risk. Surfactant proteins can also be helpful diagnostic purposes in COVID-19.
      PubDate: Thu, 04 Aug 2022 00:00:00 +030
       
  • INTERSTITIAL CYSTITIS AS A PLAUSIBLE CAUSE OF OVERACTIVE BLADDER IN
           SYSTEMIC SCLEROSIS: A HYPOTHESIS

    • Authors: Neslihan Gokcen
      Abstract: Patients with chronic inflammatory disease of the bladder, known as interstitial cystitis (IC), tend to have autoimmune diseases, such as Sjogren’s syndrome, systemic lupus erythematosus (SLE), rheumatoid arthritis and, rarely, systemic sclerosis (SSc). SLE patients with IC are prone to present with overactive bladder (OAB) symptoms. Lower urinary tract involvement is less usual in SSc but OAB symptoms are quite common among SSc patients with lower urinary tract involvement. The underlying mechanisms of lower urinary tract involvement, including OAB, in SSc could be as follows: i) vasculopathy, ii) fibrosis and/or sclerosis of bladder wall, iii) systemic sclerosis-associated myopathy, and iv) autonomic dysfunction. However, the role of IC leading to OAB is unclear. This hypothesis suggests that in patients with SSc, OAB may be associated with IC.
      PubDate: Thu, 04 Aug 2022 00:00:00 +030
       
  • YOUTUBE AS A SOURCE OF INFORMATION ABOUT GONORRHEA

    • Authors: Erhan Kaya; Yavuzalp Solak, Burhan Fatih Koçyiğit
      Abstract: Introduction: The purpose of this study was to systematically evaluate the quality of videos on YouTube related to gonorrhea. Methods: Using the search term “gonorrhea”, the first 200 relevant videos on YouTube were saved to a file. All video parameters, including the number of views, likes, dislikes and comments were recorded. The Global Quality Scale (GQS) was used to evaluate the quality of the videos. Results: After exclusions, 144 videos were selected and evaluated by two independent observers. The median duration of the videos was calculated as 3.97 minutes. Most videos were provided by physicians (59 videos). According to the GQS scores, 47.9% (n=69) of the videos were evaluated as high quality, 19.4% (n=28) as intermediate quality, and 32.6% (n=47) as low quality. There were significant differences in video length between the high, intermediate, and low-quality groups (p<0.001). Conclusion: YouTube can be considered an important source of gonorrhea videos.
      PubDate: Thu, 04 Aug 2022 00:00:00 +030
       
  • ANALYSIS OF RETRACTED PUBLICATIONS FROM KAZAKHSTAN

    • Authors: Burhan Fatih Koçyiğit; Ahmet Akyol
      Abstract: Introduction: Retraction is a mechanism to prevent the dissemination of erroneous, misleading, or biased data and information. Various factors can cause retraction. In this article, we focused on Kazakhstan data and aimed to present an analysis of retracted publications from Kazakhstan. Methods: Data for this descriptive cross-sectional article were obtained from the 'Retraction Watch’ database without time restriction. Among the country selections, 'Kazakhstan,' 'Tajikistan,' 'Uzbekistan,' 'Kyrgyzstan,' and 'Turkmenistan' were chosen, and the number of retracted articles was recorded. For detailed analysis, Kazakhstan data were focused on and further analyses were performed on Kazakhstan data. Article title, authors, time interval (in days) from publication to retraction, date of retraction, source of publication, subject area of publication, publication type, and retraction reason were recorded in an Excel file. Results: The number of retracted publications was detected as 64 from Kazakhstan, 49 from Tajikistan, 17 from Uzbekistan, 12 from Kyrgyzstan, and 1 from Turkmenistan. Kazakhstan data were as follows: The median time interval between publication date and retraction date was 475 (46 - 2074) days. Retraction reasons were listed as: Plagiarism (n = 22), peer review issues (n = 21), duplication (n = 11), author disagreements and conflict (n = 5), error (n = 5), fraud (n = 2), ethical issues ( n = 1), publication issues (n = 1), and unknown (n = 1). The three areas with the most retracted articles were engineering (n = 22), education (n = 21), and technology (n = 12). Conclusion: Kazakhstan was first among the five Central Asian countries in terms of the number of retracted publications. Plagiarism, peer review issues, and duplication were at the forefront of the retraction reasons. There is a need for approaches to increase the knowledge of researchers in Kazakhstan about the retraction reasons and ethical research conditions.
      PubDate: Thu, 04 Aug 2022 00:00:00 +030
       
  • PEERING, VIEWING AND REVIEWING: WHAT MAKES A PEER REVIEW GOOD

    • Authors: Mohini; Sakir Ahmed
      Abstract: Peer review is an integral part of an ethical scientific publication process. Though not perfect, it has not been replaceable in the last couple of centuries since the advent of scientific journals. Recent innovations include online anonymized credits for peer review that can be used to augment an academician’s resume. Submissions and retraction are ever growing, increasing the demands from peer reviewers. The rewards may not seem commensurate but any person of science should contribute to peer review as a guardian of science. This short review looks at the ideal peer review along with inherent challenges. It makes suggestions on how novice and intermediate reviewers can improve their contributions as well as introduces various resources relevant for peer review.
      PubDate: Thu, 04 Aug 2022 00:00:00 +030
       
  • INFLUENCE OF CITATION PRACTICES ON ACADEMIC ASSESSMENT

    • Authors: Horacio Rivera
      Abstract: In writing scientific papers, proper citation and referencing are crucial and thereby should be taught to graduate students and novice researchers as tools for counteracting the pervasive errors in citing, quoting, and referencing. Although the relevance of citation counts and derived indicators such as the h-index in assessing research performance is out of question, this emphasis has resulted in an “impact or perish” culture featuring post-production misrepresentation and related misbehaviors. Herein, I appraise the use of citations in academic assessment, citations in original vs. review articles, convenience and country of origin biases, and some related issues. The current landscape highlights that formal instruction on citation practices and their implications should be included in graduate programs and enduringly reinforced by mentors in laboratories.
      PubDate: Thu, 04 Aug 2022 00:00:00 +030
       
  • THE BLARING SILENCE

    • Authors: Paulami Deshmukh
      Abstract: THE BLARING SILENCE
      PubDate: Thu, 04 Aug 2022 00:00:00 +030
       
  • MY LIFE AS A STUDENT AND RESEARCHER

    • Authors: Pankti Mehta
      Abstract: MY LIFE AS A STUDENT AND RESEARCHER
      PubDate: Thu, 04 Aug 2022 00:00:00 +030
       
  • MAY AUTHORS’ PUBLISHED ARTICLES LAST FOREVER!

    • Authors: Ilke Coskun Benlidayi
      Abstract: MAY AUTHORS’ PUBLISHED ARTICLES LAST FOREVER!
      PubDate: Thu, 04 Aug 2022 00:00:00 +030
       
  • CYTOKINES AS POTENTIAL MARKERS OF COVID-19 SEVERITY AND OUTCOMES

    • Authors: Yuliya Fedorchenko; Olena Zimba
      Abstract: The continual propagation of SARS-CoV-2 has changed health care systems globally. Ranging degrees of clinical severity in COVID-19 patients have been noted in numerous literature sources. Cytokines play a crucial role in the development of key immunological processes in COVID-19. SARS-CoV-2 causes imbalance of the immune system and might culminate in cytokine storm and multiple organ involvement. The prevailing role of some special cytokines might serve as indicators of disease severity. Further stratification of patients in the context of specific cytokines can be beneficial for diagnosing disease stages. It can prevent critical states owing to timely diagnosis and targeted therapy. Targeting peculiar cytokines can markedly reduce complications. The aim of this article is to comprehensively overview the role of the main cytokines in COVID-19 pathogenesis and distinguish prognostic factors. Insights into specific cytokine involvement in COVID-19 pathogenesis may open new avenues for diagnosing hyperinflammatory COVID-19, predicting its outcomes and providing individualized cytokine-targeted therapeutic approaches.
      PubDate: Tue, 29 Mar 2022 00:00:00 +030
       
  • SEASONAL VARIATIONS AND BEHÇET’S DISEASE ACTIVITY

    • Authors: Döndü Üsküdar Cansu; Cengiz Korkmaz
      Abstract: Behçet’s disease (BD) is a systemic vasculitis with mucocutaneous manifestations such as recurrent oral ulcers and genital ulcers in addition to major organ involvements including the vascular and central nervous systems. Many studies have found that the prevalence of clinical symptoms of BD varies by geographical region. The course of BD is characterized by relapses and remissions. Infectious agents and altered microbiomes have been blamed for exacerbations of the disease. Stress, physical exhaustion, mechanical oral trauma, and hormonal effects have been specifically associated with flare-ups. A seasonal pattern in the activation of certain diseases, such as rheumatoid arthritis and systemic lupus erythematosus, has been reported. However, the relationship, if any, between the seasonal changes and the symptoms and organ involvements of BD has yet to be determined. In this review, we discussed whether clinical findings in BD patients are related to the seasons in terms of activation.
      PubDate: Tue, 29 Mar 2022 00:00:00 +030
       
  • SMOKING AND BUERGER’S DISEASE: FROM HYPOTHESES TO EVIDENCE SYNTHESIS

    • Authors: Bahare Fazeli; Mitra Masoudian
      Abstract: Early after the definition of thromboangiitis obliterans (TAO), it was noticed that TAO patients are almost always tobacco smokers. Later on, the relationship between continued smoking and TAO prognosis was documented. Consequently, smoking came to be considered as the main cause of TAO. However, it is still unknown why, amongst millions of smokers, only a small number develop TAO. It also remains unknown why, of the TAO patients who continue smoking, only half of them show aggravation and undergo amputations. The aims of this review are to investigate evidence in support of or against the relationship between TAO and smoking, according to the TAO-related literature published from 1908 to January 2022, and to discover the possible role of smoking in TAO pathophysiology. Taken together, it appears that smoking predisposes TAO patients toward the potential harmful effects of the main aetiology and helps the main aetiology to develop vascular lesions. Therefore, smoking cessation would almost always be helpful for improving the prognosis of TAO patients and reducing disease manifestation. However, concluding that smoking is not the main aetiology of TAO would open a new door to finding the true main aetiology of TAO and to discovering the appropriate treatment and medical management of patients who fail to stop smoking.
      PubDate: Tue, 29 Mar 2022 00:00:00 +030
       
  • A CLASSIFICATION SYSTEM FOR POST-ACUTE SEQUELAE OF SARS CoV-2 INFECTION

    • Authors: Leonard A. Jason; Mohammed F. Islam
      Abstract: This study aimed to contribute to the development of a research case definition for post-acute sequelae of SARS CoV-2 infection (PASC) using a PASC data set and experiences from case definitions developed for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).  Our database included patients with PASC who provided self-report symptomology during the onset of infection and the time of survey completion (post-infection).  We found that we could distinguish between those with mild, moderate, and severe PASC.  Regarding the proportion meeting an ME/CFS case definition, we found 0% in the mildly impaired group, 30.6% to 62.6% in the moderately impaired group, and 74.3% to 89.0% in the severely impaired group. Based on these preliminary data, we propose a 5-part classification system for PASC.  Axis 1 involves the variant of the COVID infection and the type of documentation of the infection. Axis 2 involves the time elapsed since infection. Axis 3 involves the type of medical collateral damage to different organs. Axis 4 involves functional impairment classified into three categories: mild, moderate, or severe.  Finally, Axis 5 is the identified symptoms. Finally, if the patient has been sick for 6 or more months, it is important to determine whether the person has met the ME/CFS criteria.  This proposed 5-part classification system for PASC might bring considerable clarity to diagnosing PASC.   
      PubDate: Tue, 29 Mar 2022 00:00:00 +030
       
  • PLAGIARISM AND ITS REPERCUSSIONS: A PRIMER ON RESPONSIBLE SCIENTIFIC
           WRITING

    • Authors: Pankti Mehta; Sayan Mukherjee
      Abstract: Background: Plagiarism, in simple words meaning theft of ideas or text, is a grave scientific misconduct that is talked about frequently, however is notable in its conspicuous absence from the formal educational curriculum. Students and young researchers tend to engage in this malpractice, intentionally or unintentionally, due to various reasons. Aim: In this review, we aim to discuss a clear concept about plagiarism from its origin to its consequences, with special considerations about its status in the COVID-19 pandemic. This lucid conceptualization will help young authors invest in original research in terms of both the idea and the script, avoiding unnecessary rejections and breach in medical ethics. Search Strategy: An electronic search strategy was performed on MEDLINE using the following keywords: “Plagiarism” OR “Plagiarism AND reasons” OR “Plagiarism AND consequences OR retractions” OR “Plagiarism AND detection”. Results: Of 2112 articles obtained, 36 were selected for the review. The main reasons for this malpractice were pressure for publication under a limited time frame along with a lack of training for scientific writing. The forms of plagiarism observed include intentional and unintentional, theft of ideas, copying verbatim, graphics, self-plagiarism and translational plagiarism. Use of various software are available for detection of plagiarism like iThenticate, Turnitin Feedback Studio, Grammarly etc along with careful reviewing by authors, reviewers and editors can detect this menace and help maintain originality in science. The consequences can be severe, ranging from defamation to monetary to legal action against the authors. Conducting interactive workshops on scientific writing along with promoting creativity in thought at the level of grass-root education is the key to preventing the scientific misconduct of plagiarism amongst students and young researchers. Conclusion: Plagiarism is a serious scientific misconduct that must be discussed with students and young researchers, and its prevention is the key to fostering growth in medical science and academics.
      PubDate: Tue, 29 Mar 2022 00:00:00 +030
       
  • HOSPITAL-MEDIA RELATIONSHIP AND PATIENTS’ PRIVACY: CODIFYING THE
           ETHICAL GUIDELINE

    • Authors: Pooneh Salari; Mahshad Noroozi, Alireza Parsapour
      Abstract: The hospital-media relationship could be mutually beneficial. Appealing to maximum readers and surviving in business are priorities in journalism. Without adherence to an ethical framework and main ethical principles including privacy and confidentiality, some detrimental impacts may occur. Thus, we aimed at codifying an ethical guideline for hospital-media relationship in Iran to maintain a proper and ethical relationship by emphasizing on patients’ privacy and confidentiality. The study was performed using the qualitative approach in two phases. The current policies and relevant reports in the literature were reviewed and their contents were analyzed. Subsequently, the first draft of the guideline was codified which was followed by the second phase in which the draft was finalized by two focus groups. Finally, a draft of an ethical guideline consisting of 79 articles in 6 themes was developed including the general principles, work flow in hospital-media relationship, duties of hospital representative, physicians’ guide, media guide, and patients’ guide. The guideline focuses on patients’ privacy, confidentiality and the privacy of the healthcare system in mutual hospital-media relationships. It is suggested that by implementing the guideline, the patients’ right would be respected and the public trust to the healthcare system will be fostered.
      PubDate: Tue, 29 Mar 2022 00:00:00 +030
       
  • MY LIFE AS A RESEARCHER AND EDITOR

    • Authors: Takako Kojima
      Abstract: MY LIFE AS A RESEARCHER AND EDITOR
      PubDate: Tue, 29 Mar 2022 00:00:00 +030
       
  • QUALITY PEER REVIEW IS ESSENTIAL FOR SCHOLARLY PUBLISHING

    • Authors: Ilke Coskun Benlidayi
      Abstract: QUALITY PEER REVIEW IS ESSENTIAL FOR SCHOLARLY PUBLISHING
      PubDate: Tue, 29 Mar 2022 00:00:00 +030
       
 
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