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SciMedicine J.     Open Access   (Followers: 2)
Emerging Science J.     Open Access   (Followers: 1)
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SciMedicine Journal
Number of Followers: 2  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2704-9833
Published by Ital Publication Homepage  [2 journals]
  • Serum Soluble Transferrin Receptor and Transferrin Levels among Regular
           Blood Donors

    • Authors: Samuel K. Appiah, Simon B. Bani, Charles Nkansah, Kofi Mensah, Gabriel Abbam, Felix Osei-Boakye, Samira Daud, Charles A. Derigubah, Christopher Nkrumah, Dorcas Serwaa, Vincent Kawuribi, Deborah E. Nkansah, Benjamin O. Opoku, Catherine A. Avero, Yeduah Quansah, Candy A. E. Wilson, Felix E. Chukwurah
      Pages: 101 - 110
      Abstract: Background: The study evaluated the effects of regular blood donation on serum transferrin and soluble transferrin receptor levels at Wenchi Methodist Hospital. Methods: This was a hospital-based cross-sectional study conducted at the Medical Laboratory Department of the Wenchi Methodist Hospital in the Bono Region of Ghana. A total of eighty-nine (89) venous blood samples from apparently healthy blood donors were analyzed. Complete blood count parameters were analyzed using an automated haematology analyzer and serum transferrin and transferrin receptor using ELISA. The data were analyzed using SPSS version 22.0. Results: Haemoglobin (p<0.001) and HCT (p=0.004) were significantly lower among the regular blood donors compared with the first-time donors. Regular blood donors had relatively higher serum transferrin (p<0.001) and soluble transferrin receptor levels (p<0.001). A negative correlation was observed between Hb and serum transferrin (r=-0.552, p<0.001), as well as Hb and serum soluble transferrin receptor (r=-0.552, p<0.001). Remunerated donors had lower Hb (p=0.001) and HCT% (p=0.001) but a higher transferrin receptor (p=0.041) than non-remunerated donors. Conclusion: Regular blood donors had relatively lower erythrocyte parameters but higher serum transferrin and soluble transferrin receptors, indicating a possible reduction in serum iron and iron stores. Moderate negative correlations exist between Hb and both transferrin and soluble transferrin receptors. Again, remunerated donors had lower erythrocyte parameters but higher transferrin and soluble transferrin receptors than non-remunerated donors. Periodic assessment of iron parameters among regular blood donors is recommended. A future longitudinal study to assess the entire iron profile of regular blood donors is recommended. Doi: 10.28991/SciMedJ-2022-04-03-01 Full Text: PDF
      PubDate: 2022-09-01
      DOI: 10.28991/SciMedJ-2022-04-03-01
      Issue No: Vol. 4, No. 3 (2022)
  • A Prevalence Risk Analysis of Waterborne Transmission of SARS-CoV-2

    • Authors: Abdullah R. Alanzi, Mohammad A. Parvez, Abdulrahman R. Alruwaili, Mohammad K. Parvez
      Pages: 111 - 119
      Abstract: We statistically analyzed 31 published studies comprising 113 water samples collected from 17 countries for SARS-CoV-2 positivity. The pooled estimated prevalence of viral RNA in the tested samples was 64.1% [95% CI:51.6%, 74.9%] with considerable heterogeneity (I2: 90.1%, P<0.001). Notably, wastewater, sewage, hospital septic-tank, biological sludge, and effluent demonstrated statistical significance (P<0.05) for RNA positivity. The country-wise pooled estimated prevalence for Germany, India, Turkey, Spain, the Netherlands, Italy, the USA, and Japan were 88% (76%, 94%), 85% (33%, 98%), 83% (43%, 97%), 78% (54%, 92%), 60% (41%, 77%), 53% (36%, 70%), 53% (27%, 77%), and 25% (13%,43%), respectively. Further subgroup analyses showed that the prevalence of SARS-CoV-2 among the tested water samples was significantly higher in middle-income countries compared to high-income groups. Our data, therefore, suggests wastewater-based epidemiological surveillance as an important tool for community-wide monitoring of SARS-CoV-2. Doi: 10.28991/SciMedJ-2022-04-03-02 Full Text: PDF
      PubDate: 2022-09-01
      DOI: 10.28991/SciMedJ-2022-04-03-02
      Issue No: Vol. 4, No. 3 (2022)
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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