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Mersin Üniversitesi Sağlık Bilimleri Dergisi
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ISSN (Online) 1308-0830
Published by Mersin Universitesi Homepage  [5 journals]
  • Investıgatıon of the assocıatıon of S422l variation ın the ATP
           dependent potassıum channel gene (KCNJ8) wıth coronary artery dısease

    • Authors: Didem SEÇER; Merih AKKAPULU, Metin YILDIRIM, Ahmet ÇELİK, Özden VEZİR, Nehir SUCU, Ali YALIN
      Abstract: Aim: Coronary artery disease (CAD) is one of the diseases with the highest mortality rate in the world, being the first cause of death in the United States and other developed countries. In order to increase the life expectancy and quality of individuals, it is important to determine the genetic background of the disease in order to learn the presence or absence of a predisposition to coronary artery disease in the early period and to take precautions accordingly. KATP channels are encoded by the Kir6 and SUR subunits KCNJ8 (Kir6.1), KCNJ11 (Kir6.2), ABCC8 (SUR1) and ABCC9 (SUR2) genes. ATP-dependent potassium channels containing Kir6.1 and SUR2 proteins are critical in regulating vascular tone, particularly in the coronary arteries. Method: In our study, we investigated whether the S422L variation of the KCNJ8 gene, which is thought to be a risk factor, is associated with coronary artery disease. In this context, 100 patients with 50% or more stenosis in their coronary arteries by coronary angiography and 100 individuals with 50% or less stenosis were included in the study as the control group. S422L polymorphism was determined from the blood samples taken from the subjects using the Tetra-Primer ARMS PCR method. Results: In this study, no significant relationship was found between the S422L variation and coronary artery disease. Conclusion: We thought that it would be beneficial from a genetic point of view to examine the relationship between variations in KATP genes and coronary artery disease with studies to be conducted on larger samples.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Knowledge, attitudes and practices of nurses toward coronavirus disease

    • Authors: Diğdem LAFÇI; Vecihe DÜZEL GÜNDÜZ
      Abstract: Aim: The research conducted as a descriptive study to determine the evaluation of the knowledge, attitudes and practices of nurses working in a city hospital about COVID-19. Methods: "Introductory Information Form" and "Information, Attitudes and Behaviors Questionnaire Form about COVID-19" were created by the researchers according to the literature. The data of the study were collected through an online questionnaire between 1 February 2021 and 1May 2021, and 236 nurses participated in the research. Frequency, percentage, mean and standard deviation were used in the evaluation of the data. Results: Nurses’ attitudes toward COVID-19; 41.5% “afraid of occupational exposure due to COVID-19 infection”, 52.5% “afraid of infect their family members by occupational exposure infection”, 45.8% “feeling themselves depressed/tired due to current pandemic” , 38.6% “feeling stressed is affecting their duties”, 41.1% “emotions of stress is affecting their relationship with their colleagues and family members”. Nurses' practices to prevent COVID-19 were; 56.4% “use alcohol-based hand scrubs or soap and water before touching a patient”, 60.6% “use personal protective equipment during care”, 32.6% “avoid close contact with patients who have respiratory symptoms”. Of the nurses, 46.6% stated that "individuals who have traveled to infected areas in the last 14 days or have a history of contact with a COVID-19 case", 44.1% stated that "individuals who experience suspicious symptoms of COVID-19 such as fever, dry cough and shortness of breath", 46.6% " stated that individuals who panic because of suspicious exposure should have a laboratory test. Conclusion: It was determined that nurses' knowledge, attitudes and practices towards coronavirus disease were at a sufficient level.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Coexistence of pseudotumor cerebri and Chiari malformation Type 1

    • Authors: Barış TEN; Celal BAĞDATOĞLU, Hasan Hüsnü YÜKSEK, Gülhan TEMEL, Yüksel BALCI
      Abstract: Aim: Our aim was to find different radiological markers for the diagnosis of coexistence of pseudotumor cerebri and Chiari malformation Type 1. Method: Patients who were referred to the Department of Radiology with a clinical preliminary diagnosis of Chiari malformation Type 1 between 2007 and 2020 and whose diagnosis was confirmed radiologically by magnetic resonance imaging were evaluated retrospectively. 49 Chiari malformation Type 1 patients with both cervical and cerebral examinations and 49 control groups of the same age and sex without Chiari malformation Type 1 diagnosis were included in the study. Presence of pseudotumor cerebri radiologically from Cerebral MRI images of patients with Chiari malformation Type 1 diagnosis, presence of syringomyelia from cervical spinal MRI images, and distance of cerebellar tonsils and obex according to McRae line were evaluated in millimeters. Results: In cases with Chiari malformation Type 1 clinical and radiological diagnosis, patients with radiological diagnosis of pseudotumor cerebri had lower cerebellar tonsils and Obex than those who were not, and the rate of accompanying syringomyelia seemed to be higher. However, there was no statistically significant difference between the two groups. Conclusion: Coexistence of pseudotumor cerebri and Chiari malformation Type 1 was more common than expected. The treatment protocol is different in the coexistence of pseudotumor cerebri and Chiari malformation Type 1, therefore this increases the importance of diagnosing the coexistence. Further radiological imaging studies are needed to find different radiological markers in the diagnosis of pseudotumor cerebri and Chiari malformation Type 1 coexistence.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • The knowledge and management of extravasation of medical personnel working
           in the neonatal ıntensive care unit

    • Authors: Ayşen ORMAN; Yalçın ÇELİK, Nihan ÖZEL ERÇEL
      Abstract: Aim: It is aimed to examine the knowledge and management of extravasation related to the vascular pathway among nurses and doctors working in the neonatal intensive care unit in this study. This study was the first survey study to evaluate the knowledge and management of extravasation. Method: This study, which was designed as aprospective cross-sectional survey study, included 300 health professionals working in the neonatal intensive care unit. Due to the conditions imposed by the pandemic, neonatal health workers who were actively engaged in in the neonatal intensive care unit were sent the 28 questions questionnaire form prepared via ”Google Forms" to their mobile phones and e-mail addresses. Results: Health professionals in the study reported that the most important health care related risk factor in the development of extravasation was insufficient follow-up while administering high-risk drugs (p=0.028). Risk factors for the baby were identified as prematurity and hypotension/hypoperfusion (p<0.001). The first approach in the treatment of extravasation was to stop the infusion and withdraw the intravenous cannula (p<0.001). Healthcare workers faced severe conditions requiring extravasation at a rate of 91.6% and limb loss or plastic surgery at a rate of 58% during their professional lives. Conclusion: All health workers working in the neonatal intensive care unit should be provided with up-to-date information by continuing in-service training, and extravasation treatment protocols should be developed to prevent variations approaches.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Symptomatic Lumbosacral Transitional Vertebra (Bertolotti Syndrome) as a
           cause of low back pain: Classification and imaging findings

    • Authors: Barış TEN; Meltem Nass DUCE, Hasan Hüsnü YÜKSEK, Gülhan TEMEL, Yüksel BALCI, Kaan ESEN
      Abstract: Aim: Our aim was to determine the pathologies that mostly cause low back pain, to reveal the ratio of Bertolotti Syndrome among these pathologies and possible gender-age discrimination. To group Lumbosacral Transitional Vertebrae according to Castellvi classification and to find their ratios. Method: Images and reports of 357 patients who had Sacroiliac joint Magnetic Resonance Imaging, mostly due to low back pain, between March 2020 and October 2021 were evaluated by a radiologist specialized in musculoskeletal radiology. Results: The mean age of patients with Bertolotti Syndrome was 43.9, and the mean age of patients without Bertolotti Syndrome was 44, and no correlation was found between Bertolotti Syndrome and patient age (p=0.976). The age range of patients with Bertolotti Syndrome was 15-77 years. Of the patients with Bertolotti Syndrome, 20% were under 30 years of age and 50% were under 40 years of age. Considering the gender distribution of patients with and without Bertolotti Syndrome, no gender discrimination was observed in Bertolotti Syndrome (p=0.572). According to the Castellvi classification, the incidence of groups is 10% in Type 1a, 11.4% in Type 1b, 35.7% in Type 2a, 17.1% in Type 2b, 4.3% in Type 3a, 12.9% in Type 3b and Type 4 It was found to be 8.6% in . The main pathologies causing lower lumbar pain were active-chronic sacroiliitis, vertebral and disc degenerations, and facet joint arthrosis. Bertolotti Syndrome, which is the cause of pain from Lumbosacral Transitional Vertebra, was the most common pathology with a frequency of 2.8% after these pathologies that appeared to be the main ones. Conclusion: According to our study results, although Bertolotti Syndrome begins to appear under the age of 30, there is no significant relationship with age. It does not show any gender discrimination. Bertolotti Syndrome; It is one of the most common causes of lower lumbar pain after sacroiliitis, osteodegeneration and discopathic changes. There are different hypotheses in the literature on the etiology of Bertolotti Syndrome and there is no common opinion. For this reason, multicenter studies with a large number of patients are needed.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Evaluation of eating behavior disorders in Nutrition and Dietetics
           department students

    • Authors: Pınar SÖKÜLMEZ KAYA; Yasemin AÇAR
      Abstract: Objective: To evaluate the eating behavior disorders in the nutrition and dietetics department students. Method: This study was conducted on a total of 210 volunteer students (201 female and 9 male), studying at Ondokuz Mayıs University Department of Nutrition and Dietetics. A questionnaire consisting of demographic characteristics, anthropometric measurements, Eating Attitude Test (EAT-40), Orthorexia-15 Scale (ORTO-15) and Bulimic Investigatory Test Edinburgh Test (BITE) was applied to the students. The analysis of the data was evaluated with the SPSS 24.0 package program. Results: The students EAT-40, ORTO-15 and BITE test mean scores were 12.8±7.8 points, 37.8±3.4 points and 13.5±6.6 points, respectively. According to the ORTO-15 cutoff score, 73.3% of the students were found to be orthorexic. It was determined that BITE test mean scores increased as BMI increased (p<0.05). There was a negative correlation between EAT-40 score and ORTO-15 score, and a positive relationship between BMI groups and BITE score (r=-0.246), (r=0.437), (p<0.05). Conclusion: According to the results of this study, it was found that deterioration in eating attitude was associated with an increase in orthorexia nervosa tendency. In addition, it has been observed that binge eating is an effective factor in increasing BMI. If the eating disorders of the Nutrition and Dietetics department students who are educated in the field of health and nutrition are like this, the extent of the nutritional problems in other university students may be more serious. For this reason, university students'eating attitudes should be evaluated and all students should be informed about healthy nutrition and eating disorders from childhood by giving them nutrition education.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • The evaluation of the effect of cold spray application for the pain of
           enjection in the enjection of intramuscular penicilin

    • Authors: Mehmet Mehdi ÇETİN; Gülçin AVŞAR
      Abstract: Aim: This study was conducted to evaluate the effect of cold spray application on pain in reducing pain associated with intramuscular penicillin injection in children. Method: The population of this experimental type of research was consisted of patients who applied to the pediatric emergency department of a hospital for intramuscular penicillin injection between March 10 and June 10, 2021. The sample of the study was consisted of 55 children aged 7-17 who met the inclusion criteria and agreed to participate in the study. In addition, each patient formed his/her own control group to eliminate individual differences in pain. Personal information form and Visual Analogue Scale (VAS) were used to collect data. Results: As a result of the research, it was determined that the mean VAS score of the control group (X:7.27, SD:1.59) was significantly higher than the mean VAS score of the experimental group (X:4.55, SD:1.87) (p<0.001). Conclusion: In the study, it was determined that cold spray application before intramuscular penicillin injection in children significantly reduced injection pain.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Turkish adaptation of the Health Action Process Approach based physical
           activity inventory for patients with schizophrenia

    • Authors: Zeliha YAMAN; Önder SÜNBÜL, Celil ÇAKICI, Mualla YILMAZ
      Abstract: Objective: In this study, it was aimed to test the validity and reliability of the Physical Activity Inventory, which was developed from the Health Action Process Approach (HAPA) model. Method: In adapting the physical activity inventory to Turkish, the adaptation and translation process procedure of the scales recommended by the World Health Organization was followed. Within the framework of this procedure, the inventory was translated into Turkish using the translation-back translation method. Explanatory and confirmatory factor analysis was used to examine the construct validity of the inventory in Turkish adaptation. Explanatory factor analysis was used to examine the construct validity in adapting the inventory to Turkish. Reliability was evaluated with internal consistency tests. Reliability was determined by the combined reliability (CR) value, and convergent and discriminant validity were also examined. Results: In the exploratory factor analysis, it was observed that all scales had a one-dimensional structure, as in the original inventory, except for the "perceived risk scale" in the motivational phase. Except for the “perceived risk scale” in the motivational phase, the CR values of all scales are quite high. It was evaluated that the scales constituting the motivational and voluntary phases had discriminative and convergent validity. Conclusion: According to the findings of this study, it was determined that the physical activity inventory had valid and reliable results. It can be said that this inventory can be used in studies to reveal the determinants of physical activity behavior within the framework of the HAPA model in schizophrenia patients in Turkey
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • The effects of socio-demographic characteristics and eating attitudes of
           nursing students’ on orthorexia nervosa

    • Authors: Emine KAPLAN SERİN; Kevser IŞIK, Ebru YILDIZ KARADENİZ
      Abstract: Aim: This research was carried out to determine the effects of socio-demographic characteristics and eating attitudes of nursing students on orthorexia nervosa. Method: The universe of the descriptive study consisted of all students studying at the Nursing Department of the Faculty of Health Sciences at KSU. The sample consisted of 164 students who agreed to participate in the research. Data were collected via Google form using an introductory questionnaire, eating attitude scale and ortho-15 scale. Results: It was determined that 58.5% of the students participating in the study had regular eating habits, 70.7% of them skipped meals, the average of the eating attitude scale score was 37.98 ±3.46, and the average of the Ortho-15 scale score was 37.97±3.45. Conclusion: It was determined that the body mass index of the students was in the normal range, but the risk of eating behavior disorder was high and their susceptibility to orthorexia nervosa was normal.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Nonrational drug use: The magnitude of the economic loss caused by waste
           drugs not instantly optimally prescribed, unsold and unused

    • Authors: Kürşat YURDAKOŞ; Mucize SARIHAN
      Abstract: Aim: The objective of this research was to determine the non-use reasons of the wasted medication in houses and the number, box and total price amount of them. Method: The population of this descriptive and cross sectional research included 5.648 residences in Şeyh Şamil Quarter, Sivas. The sample was determined as 250 residences in the condition of alpha=0.05, strength=0.80 and error 5% by using G*Power 3.1 program. The data were collected by “Wasted Medication Determination Form” developed by the researchers. In between-groups comparisons, Pearson Chi-square test was used. Results: Total 740 boxes of wasted medication were found in 250 residences under 179 different medication names. The total number of the medications was 25.641 valued at 23.949 TL (3.274 $). Those not used with the thought that they were not useful (66.5%) were 16.629 and 15.044 TL (2.056 $), and women had higher rates of not using them with this thought than men (p<0.05). There were 7.033 (18.5%) antihypertensives valued at 5.461 TL (746 $), 2.056 (6.2%) antithrombotic medications valued at 3.184 TL (435 $) and 3.181 (20.1%) anti-inflammatories/analgesics valued at 1.915 TL (262 $). Conclusion: Consequently, it was revealed that the quantity and price of the wasted medications in residences were of high amount. In this context, policies on the sale of the medications by numbers instead of boxes in pharmacies can be developed. Also, medications kept unused in the houses can be ensured to be reused by the Ministry of Health.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Retrospective evaluation of epidemiological, clinical and Real-time PCR
           cycle threshold of SARS-CoV-2 infection positive pediatric patients

    • Authors: Gül BAYRAM; Harun GÜLBUDAK, Taylan BOZOK, Mehtap AKÇA, Ali Türker ÇİFTÇİ, Necdet KUYUCU, Gönül ASLAN
      Abstract: Aim: Risk factors that cause severe clinical outcomes caused by COVID-19 are better defined in adult patients than in the pediatric patient group. In this study, it was aimed to evaluate the relationship between socio-demographic characteristics, clinical findings and cycle threshold (Ct) value in pediatric patients who applied to our hospital with the suspicion of COVID-19 and were found to have a positive SARS-CoV-2 test. Method: In the study, 2971 pediatric patients with positive SARS-CoV-2 RT-qPCR test in Mersin University Hospital COVID-19 laboratory between 1 May 2020 and 31 October 2021 were included in the study. The SARS-CoV-2 RT-qPCR test was performed on nasopharyngeal and oropharyngeal swab samples. Ct values obtained from the RT-qPCR result were classified as low, moderate, and high. Results: The most common symptoms in pediatric patients with positive SARS-CoV-2 infection were fever 41.5%, cough 28.6% and sore throat 24.4%, respectively. Ct values of SARS-CoV-2 positive asymptomatic and symptomatic pediatric patients are low (<24) and the patients are in the high risk group. When the relationship between symptoms and Ct groups in SARS-CoV-2 positive children was evaluated, it was determined that patients with fever (43.1%), fatigue (18.8%) and headache (16.3%) were in the high viral load group. Conclusion: Most of the contact patients in our study were thought to have low Ct value because they were exposed to a family member with COVID-19. Therefore, monitoring, control and isolation of this contact group with high potential contagion is an important point in terms of public health.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • The relationship between the prevalence of urinary incontinence and
           quality of life in university students

    • Authors: Nurdilan ŞENER; Ayça ŞOLT
      Abstract: Objective: This study was conducted to investigate the relationship between urinary incontinence prevalence and quality of life in university students.Method: 487 university students participated in this descriptive and relation-seeking cross-sectional study. The research was collected online between the dates of 20.09.2021 and 20.11.2021 through google survey forms. Personal information form, Urinary Distress Inventory-6/UDI-6 and Incontinance Impact Questionnaire-7/ IQ-7 were used to collect data. Data were analyzed with SPSS 22 program using mean, standard deviation, percentile and Man Whitney U test. Significance value was accepted as p value less than 0.05.Results: The mean age of the students who participated in the study was 20.42±2.14. It was determined that 17.5% of the students had urinary incontinence, and 11.2% of the students got stuck in their urine while going to the toilet. When the relationship between incontinence and quality of life was evaluated, it was determined that the quality of life of the students with incontinence was statistically significantly lower than the students without incontinence (p<0.05).Conclusion: In the study, it was determined that urinary incontinence negatively affected the students' quality of life.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Transmitted diseases from animals to human and food safety

      Abstract: Today, a growing population with global warming, climate change, migration to cities from villages and possible biological warfare on the identification and control of the transmitted diseases from animals to humans makes it necessary to reduce and prevent the infectious diseases among animals and from animal to human. Zoonoses that transmitted diseases from animal to human depending on the ecological conditions and other factors in our country will be the subject of the study in this review. Many of fecal origin coliform bacteria in the zoonotic diseases such as typhoid, typhus, dysentery diseases, Tuberculosis, Q fever, anthrax, tetanus (Clostridial Disease), listeriosis, toxoplasmosis, glanders, avian influenza, Hepatitis A (infectious Hepatitis A), rabies, crimean-congo hemorrhagic fever (CCHF), hydatidcysts (Hydatidosis) are a threat to human and animal health. There are about 200 zoonotic diseases. Public health and food safety threats and even biological warfare constitutes eighty percent of the components used in the Zoonoses, in terms of public health, veterinarian, medical doctors, food engineers and agricultural engineers, as relevant Professional coordination between the branches working with public health and in terms of the security of the country by taking such as preventive medicine, public health, food safety appropriate measures are evaluated within the basic issues should be ensured. The implementation of Good Manufacture Practice (GMP) is a legal requirement and is the discipline to be followed in zoonoses concerning food safety. Hazard Analysis Critical Control Points (HACCP) Hazard Analysis at Critical Control Points is international food standard on the basis of food safety. Preventive approach principle and identifying critical control points and solving the problem ensure safe food production.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Analysis of patients undergoing ürooncological surgery at Mersin
           University Hospital

    • Authors: Mert BAŞARANOĞLU; Veysi TUNÇ, Murat BOZLU, Yasemin YUYUCU KARABULUT, Gözde ARSLAN, Erdem AKBAY, Ercüment ULUSOY, Selahittin ÇAYAN, Hasan Erdal DORUK, Erim ERDEM, Mesut TEK
      Abstract: AimThis study aims to evaluate the distribution of urogenital cancer patients diagnosed and/or treated between 2010-2020 in Mersin University Faculty of Medicine Hospital, Department of Urology, according to age, gender, histopathological types, and years.MethodThe records of patients who applied to the Urology Department of Mersin University Medical Faculty Hospital between January 2010 and June 2020 and whose tissue samples were taken as a result of surgical intervention, whose pathology report was interpreted in favor of malignancy, were examined. These retrospective data were obtained from the reports prepared by the Pathology Department of our hospital and kept in the information database of our hospital. Duplicate records of patients with multiple reports were eliminated. The most comprehensive data were selected from patients with relapse or progression or from patients who had multiple operations.ResultsThe samples taken from the results of the operation from 4852 patients who were operated on between 2010 and 2020 by our department were studied in the Department of Pathology, and only the data of 2000 patients who were interpreted in favor of malignancy were included in the study. As a result of the analysis of the obtained data; While the number of prostate, bladder, kidney, and testicular cancer patients among all urogenital cancers in our hospital are above the Turkey average; The number of patients with adrenal gland, ureter, and penile cancer was found below the Turkey average, and all these differences were not statistically significant.ConclusionWe believe that the analyzes of the patients diagnosed in our hospital, which is serving in the Çukurova region, can contribute to both the literature and the health plans made in our region.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • The effect of menstrual pain severity on body awareness, physical activity
           level, and sensory organization

    • Authors: Emine BARAN; Tuğba EMEKCİ
      Abstract: Aim: The aim of this study was to examine the effect of menstrual pain severity on body awareness, physical activity level, and sensory organization in women. Method: Women aged 18-30 years with menstrual pain were included in the study. Participants were divided into three groups as mild (n=47), moderate (n=28) and severe (n=18) menstrual pain-groups according to visual analog scale. The Body Awareness Questionnaire (BAQ) and the International Physical Activity Questionnaire–short form (IPAQ) were administered to the participants. Somatosensory, visual and vestibular sensory organizations of the participants were analyzed using computerized dynamic posturography. All assessments were administered during menstruation. Results: In terms of BAQ and IPAQ; severe pain-group had lower scores than mild and moderate pain-groups, and moderate pain-group had lower scores than mild pain-group (p<0.05). Severe pain-group had lower antero-posterior somatosensory test values than mild and moderate pain-groups, and moderate pain-group had lower antero-posterior somatosensory test values than mild pain-group (p<0.05). Severe pain-group had lower antero-posterior vestibular test values than mild pain-group (p<0.05). Severe pain-group had lower medio-lateral somatosensory test values than mild and moderate pain-groups (p<0.05). The severe pain-group had lower medio-lateral vestibular test values than the mild pain-group, and the moderate pain-group had lower medio-lateral vestibular test values than the mild pain-group (p<0.05). Conclusion: As the severity of pain increased, BAQ, IPAQ, and somatosensory and vestibular sensory organization results decreased. Preferring physical activity methods that increase body awareness to cope with menstrual pain may provide more effective results in reducing menstrual pain and improving sensory organization.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • The effect of assisted reproductive technology on morbidity and mortality
           of twin premature

    • Authors: Burak CERAN; Ufuk ÇAKIR, Ali Ulaş TUĞCU, Cüneyt TAYMAN
      Abstract: Objectives: It is thought that twin neonates born from pregnancies resulting from assisted reproductive technology (ART) are clinically riskier than twin neonates born from spontaneous pregnancy. However, information on the risks in premature infants born as a result of ART pregnancies is limited. In our study, premature twin infants born from ART and spontaneous pregnancies were compared to clinical outcomes.Materials and Methods: All premature twin infants hospitalized in our unit between September 2019 and September 2020 and born under 32 weeks of gestation were included in our study. Demographic and clinical results of premature twins born as a result of spontaneous and ART pregnancies were compared.Results: A total of 142 premature twins, 116 (81.6%) in the spontaneous twin group and 26 (18.4%) in the ART twin group, were included in the study. Demographic and clinical features were similar between ART and spontaneous twin groups (p>0.05).Conclusion: Our study determined that premature infants born due to ART pregnancies did not have any additional risk compared to spontaneous infants. This result shows that the main determinants of clinical outcomes in premature infants are gestational week and birth weight.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Effect of selenium on impaired learning and memory performance by
           6-n-propyl-2-thiouracil in rats

    • Authors: Bilal KOŞAR; Burak TAN, Melek ALTUNKAYA, Cem SÜER, Nurcan DURSUN
      Abstract: Aim: In this study, it was aimed to reveal that the healing effect of selenium on spatial learning and memory performance impaired by hypothyroidism with 6-n-propyl-2-thiouracil in rats. Method: The study was carried out on young male Wistar albino rats weighing between 250 and 300 gr. The rats were divided into four groups which were control, hypothyroid, 5 ppm selenium supplied with 6-n-propyl-2-thiouracil and 10 ppm selenium supplied with 6-n-propyl-2-thiouracil group. Plasma fT3 and fT4 levels of rats were measured by ELISA method and hippocampus selenium levels were measured by atomic absorption spectrometry. Morris water maze test was used to evaluate learning/memory performance. Results: A significant decrease was observed in distance moved and escape latency of all groups from the first day to the fourth day of the learning test. In the statistical comparison between groups, distance moved showed an increase in the hypothyroid groups than that the control group and decrease in 10 ppm selenium supplemented hypothyroid group compared to hypothyroidism without selenium. The ratio of presence in the target quadrant decreased with hypothyroidism and increased in the group supplemented 5 ppm selenium compared to hypothyroidism without selenium. Conclusion: This study revealed that hypothyroidism may negatively affects hippocampal learning and memory function, and selenium supplementation may improve this negative effect of hypothyroidism.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • A case study: Spondyloarthropathy ' Ocraniotic arthropathy'

      Abstract: Alkaptonuria is a rare disease characterized by homogentisic acid excretion in the urine due to the deficiency of the homogentisic acid oxidase enzyme involved in tyrosine metabolism. Ochronosis, which is defined as the accumulation of metabolites in tissues and internal organs due to enzyme deficiency, causes increased pigmentation in the relevant tissue and organ pathologies. Because of its similar clinical features, it should be differentiated from many diseases such as spondyloarthropathy, diffuse idiopathic skeletal hyperostosis, juvenile idiopathic arthritis, and osteoarthritis. Although there is no specific treatment, dietary modification, pain control, patient education, and appropriate exercise program are the treatment options. In this case report, we presented a patient with a history of neck, low back pain, and knee arthritis with a diagnosis of ochronosis, which we would like to draw attention to in the differential diagnosis of spondyloarthropathy and arthritis.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • The frequency of hand eczema and related factors in nurses working in a
           university hospital

    • Authors: Ayşe ÖZCAN; Naile BİLGİLİ
      Abstract: Aim: This study aimed to determine the frequency of hand eczema and related factors in nurses working in a university hospital. Method: 601 nurses participated in this cross-sectional study. Data were collected using the Turkish NOSQ-2002/Long Version Nordic Occupational Skin Disease Detection Questionnaire. Pearson-χ2, logistic regression analyzes were used in the analysis of the data. Results: The prevalence of hand eczema in nurses was 30.6%. 76.6% of nurses with eczema worked in inpatient services, 57.6% worked more than 12 hours a day and 50% worked between 1-5 years. The prevalence of eczema was higher in women, in the 30-39 age group, in nurses with a history of eczema, allergic rhinitis, atopic condition, and allergy (p<0.05). A statistically significant relationship was found between nurses' working time, hand washing frequency, soap use, drugs/antibiotic contact, exposure to anesthetic gas, exposure to personal hygiene products, and use of make-up products (p<0.05). The risk of eczema for women was 7.5 times higher than for men, 24.8 times higher for those with a history of eczema, 18.1 times for those with allergies, and 7.6 and 3.9 times for those working in inpatient services and intensive care units, respectively. Conclusion: Hand eczema is an important health problem in nurses. As working hours, hand washing frequency, soap use, and drug/antibiotic contact increased, symptoms related to eczema increased. Within the scope of occupational health nursing, the risks that cause hand eczema in the working environment should be known and measures should be taken to reduce/eliminate the risks.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
  • Attitudes of physician candidates towards medical education and related

    • Authors: Hüseyin SELVİ; İbrahim BAŞHAN, Asena Ayça ÖZDEMİR
      Abstract: Aim: Attitudes that are tried to be gained to physician candidates during the medical education process are important in increasing the quality of both the medical education given and the health service that the physician candidates will provide throughout their professional life. In the study, it was aimed to reveal what affects the attitudes and attitudes of physician candidates towards medical education in the pre- and post-pandemic period. Method: A total of 368 physician candidates, 50.5% male and 49.5% female, were included in the study. The Attitude Scale towards Medical Education and a questionnaire consisting of questions that may affect their attitudes were applied. Variables affecting attitudes were determined with univariate and multivariate analysis methods. Results: Being female, having a high grade point average and high attendance rate caused an increase in attitude scores towards medical education, while increasing age, choosing the Faculty of Medicine due to family desire and other reasons and the presence of a physician in the family caused a decrease in attitude scores. Conclusion: It was seen that the attitudes of the physician candidates were related to their voluntarily choosing the department they studied and their gender. In addition, it was determined that the academic success and the duration of the lectures of the physician candidates who had a positive attitude towards medical education increased.
      PubDate: Sat, 31 Dec 2022 00:00:00 +030
School of Mathematical and Computer Sciences
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