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Publisher: Elsevier   (Total: 3123 journals)

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Showing 1 - 200 of 3120 Journals sorted alphabetically
A Practical Logic of Cognitive Systems     Full-text available via subscription   (Followers: 8)
AASRI Procedia     Open Access   (Followers: 15)
Academic Pediatrics     Hybrid Journal   (Followers: 26, SJR: 1.402, h-index: 51)
Academic Radiology     Hybrid Journal   (Followers: 22, SJR: 1.008, h-index: 75)
Accident Analysis & Prevention     Partially Free   (Followers: 90, SJR: 1.109, h-index: 94)
Accounting Forum     Hybrid Journal   (Followers: 25, SJR: 0.612, h-index: 27)
Accounting, Organizations and Society     Hybrid Journal   (Followers: 30, SJR: 2.515, h-index: 90)
Achievements in the Life Sciences     Open Access   (Followers: 4)
Acta Anaesthesiologica Taiwanica     Open Access   (Followers: 5, SJR: 0.338, h-index: 19)
Acta Astronautica     Hybrid Journal   (Followers: 379, SJR: 0.726, h-index: 43)
Acta Automatica Sinica     Full-text available via subscription   (Followers: 3)
Acta Biomaterialia     Hybrid Journal   (Followers: 26, SJR: 2.02, h-index: 104)
Acta Colombiana de Cuidado Intensivo     Full-text available via subscription   (Followers: 1)
Acta de Investigación Psicológica     Open Access   (Followers: 2)
Acta Ecologica Sinica     Open Access   (Followers: 8, SJR: 0.172, h-index: 29)
Acta Haematologica Polonica     Free   (Followers: 1, SJR: 0.123, h-index: 8)
Acta Histochemica     Hybrid Journal   (Followers: 3, SJR: 0.604, h-index: 38)
Acta Materialia     Hybrid Journal   (Followers: 237, SJR: 3.683, h-index: 202)
Acta Mathematica Scientia     Full-text available via subscription   (Followers: 5, SJR: 0.615, h-index: 21)
Acta Mechanica Solida Sinica     Full-text available via subscription   (Followers: 9, SJR: 0.442, h-index: 21)
Acta Oecologica     Hybrid Journal   (Followers: 10, SJR: 0.915, h-index: 53)
Acta Otorrinolaringologica (English Edition)     Full-text available via subscription   (Followers: 1)
Acta Otorrinolaringológica Española     Full-text available via subscription   (Followers: 3, SJR: 0.311, h-index: 16)
Acta Pharmaceutica Sinica B     Open Access   (Followers: 2)
Acta Poética     Open Access   (Followers: 4)
Acta Psychologica     Hybrid Journal   (Followers: 25, SJR: 1.365, h-index: 73)
Acta Sociológica     Open Access  
Acta Tropica     Hybrid Journal   (Followers: 6, SJR: 1.059, h-index: 77)
Acta Urológica Portuguesa     Open Access  
Actas Dermo-Sifiliograficas     Full-text available via subscription   (Followers: 4)
Actas Dermo-Sifiliográficas (English Edition)     Full-text available via subscription   (Followers: 3)
Actas Urológicas Españolas     Full-text available via subscription   (Followers: 4, SJR: 0.383, h-index: 19)
Actas Urológicas Españolas (English Edition)     Full-text available via subscription   (Followers: 2)
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 5, SJR: 0.141, h-index: 3)
Actualites Pharmaceutiques Hospitalieres     Full-text available via subscription   (Followers: 4, SJR: 0.112, h-index: 2)
Acupuncture and Related Therapies     Hybrid Journal   (Followers: 5)
Acute Pain     Full-text available via subscription   (Followers: 13)
Ad Hoc Networks     Hybrid Journal   (Followers: 11, SJR: 0.967, h-index: 57)
Addictive Behaviors     Hybrid Journal   (Followers: 15, SJR: 1.514, h-index: 92)
Addictive Behaviors Reports     Open Access   (Followers: 7)
Additive Manufacturing     Hybrid Journal   (Followers: 7, SJR: 1.039, h-index: 5)
Additives for Polymers     Full-text available via subscription   (Followers: 22)
Advanced Cement Based Materials     Full-text available via subscription   (Followers: 3)
Advanced Drug Delivery Reviews     Hybrid Journal   (Followers: 139, SJR: 5.2, h-index: 222)
Advanced Engineering Informatics     Hybrid Journal   (Followers: 11, SJR: 1.265, h-index: 53)
Advanced Powder Technology     Hybrid Journal   (Followers: 17, SJR: 0.739, h-index: 33)
Advances in Accounting     Hybrid Journal   (Followers: 9, SJR: 0.299, h-index: 15)
Advances in Agronomy     Full-text available via subscription   (Followers: 15, SJR: 2.071, h-index: 82)
Advances in Anesthesia     Full-text available via subscription   (Followers: 27, SJR: 0.169, h-index: 4)
Advances in Antiviral Drug Design     Full-text available via subscription   (Followers: 4)
Advances in Applied Mathematics     Full-text available via subscription   (Followers: 9, SJR: 1.054, h-index: 35)
Advances in Applied Mechanics     Full-text available via subscription   (Followers: 12, SJR: 0.801, h-index: 26)
Advances in Applied Microbiology     Full-text available via subscription   (Followers: 23, SJR: 1.286, h-index: 49)
Advances In Atomic, Molecular, and Optical Physics     Full-text available via subscription   (Followers: 16, SJR: 3.31, h-index: 42)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4, SJR: 2.277, h-index: 43)
Advances in Botanical Research     Full-text available via subscription   (Followers: 3, SJR: 0.619, h-index: 48)
Advances in Cancer Research     Full-text available via subscription   (Followers: 26, SJR: 2.215, h-index: 78)
Advances in Carbohydrate Chemistry and Biochemistry     Full-text available via subscription   (Followers: 9, SJR: 0.9, h-index: 30)
Advances in Catalysis     Full-text available via subscription   (Followers: 6, SJR: 2.139, h-index: 42)
Advances in Cell Aging and Gerontology     Full-text available via subscription   (Followers: 4)
Advances in Cellular and Molecular Biology of Membranes and Organelles     Full-text available via subscription   (Followers: 13)
Advances in Chemical Engineering     Full-text available via subscription   (Followers: 26, SJR: 0.183, h-index: 23)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 10, SJR: 0.665, h-index: 29)
Advances in Chronic Kidney Disease     Full-text available via subscription   (Followers: 9, SJR: 1.268, h-index: 45)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 29, SJR: 0.938, h-index: 33)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 18, SJR: 2.314, h-index: 130)
Advances in Computers     Full-text available via subscription   (Followers: 16, SJR: 0.223, h-index: 22)
Advances in Dermatology     Full-text available via subscription   (Followers: 12)
Advances in Developmental Biology     Full-text available via subscription   (Followers: 12)
Advances in Digestive Medicine     Open Access   (Followers: 7)
Advances in DNA Sequence-Specific Agents     Full-text available via subscription   (Followers: 6)
Advances in Drug Research     Full-text available via subscription   (Followers: 23)
Advances in Ecological Research     Full-text available via subscription   (Followers: 47, SJR: 3.25, h-index: 43)
Advances in Engineering Software     Hybrid Journal   (Followers: 27, SJR: 0.486, h-index: 10)
Advances in Experimental Biology     Full-text available via subscription   (Followers: 9)
Advances in Experimental Social Psychology     Full-text available via subscription   (Followers: 46, SJR: 5.465, h-index: 64)
Advances in Exploration Geophysics     Full-text available via subscription   (Followers: 3)
Advances in Food and Nutrition Research     Full-text available via subscription   (Followers: 52, SJR: 0.674, h-index: 38)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 16)
Advances in Genetics     Full-text available via subscription   (Followers: 17, SJR: 2.558, h-index: 54)
Advances in Genome Biology     Full-text available via subscription   (Followers: 11)
Advances in Geophysics     Full-text available via subscription   (Followers: 6, SJR: 2.325, h-index: 20)
Advances in Heat Transfer     Full-text available via subscription   (Followers: 22, SJR: 0.906, h-index: 24)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 9, SJR: 0.497, h-index: 31)
Advances in Human Factors/Ergonomics     Full-text available via subscription   (Followers: 27)
Advances in Imaging and Electron Physics     Full-text available via subscription   (Followers: 2, SJR: 0.396, h-index: 27)
Advances in Immunology     Full-text available via subscription   (Followers: 36, SJR: 4.152, h-index: 85)
Advances in Inorganic Chemistry     Full-text available via subscription   (Followers: 9, SJR: 1.132, h-index: 42)
Advances in Insect Physiology     Full-text available via subscription   (Followers: 3, SJR: 1.274, h-index: 27)
Advances in Integrative Medicine     Hybrid Journal   (Followers: 6)
Advances in Intl. Accounting     Full-text available via subscription   (Followers: 4)
Advances in Life Course Research     Hybrid Journal   (Followers: 8, SJR: 0.764, h-index: 15)
Advances in Lipobiology     Full-text available via subscription   (Followers: 2)
Advances in Magnetic and Optical Resonance     Full-text available via subscription   (Followers: 10)
Advances in Marine Biology     Full-text available via subscription   (Followers: 16, SJR: 1.645, h-index: 45)
Advances in Mathematics     Full-text available via subscription   (Followers: 10, SJR: 3.261, h-index: 65)
Advances in Medical Sciences     Hybrid Journal   (Followers: 6, SJR: 0.489, h-index: 25)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 6)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 5, SJR: 1.44, h-index: 51)
Advances in Molecular and Cell Biology     Full-text available via subscription   (Followers: 23)
Advances in Molecular and Cellular Endocrinology     Full-text available via subscription   (Followers: 10)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 9, SJR: 0.324, h-index: 8)
Advances in Nanoporous Materials     Full-text available via subscription   (Followers: 4)
Advances in Oncobiology     Full-text available via subscription   (Followers: 2)
Advances in Organ Biology     Full-text available via subscription   (Followers: 2)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 15, SJR: 2.885, h-index: 45)
Advances in Parallel Computing     Full-text available via subscription   (Followers: 7, SJR: 0.148, h-index: 11)
Advances in Parasitology     Full-text available via subscription   (Followers: 7, SJR: 2.37, h-index: 73)
Advances in Pediatrics     Full-text available via subscription   (Followers: 24, SJR: 0.4, h-index: 28)
Advances in Pharmaceutical Sciences     Full-text available via subscription   (Followers: 13)
Advances in Pharmacology     Full-text available via subscription   (Followers: 16, SJR: 1.718, h-index: 58)
Advances in Physical Organic Chemistry     Full-text available via subscription   (Followers: 8, SJR: 0.384, h-index: 26)
Advances in Phytomedicine     Full-text available via subscription  
Advances in Planar Lipid Bilayers and Liposomes     Full-text available via subscription   (Followers: 3, SJR: 0.248, h-index: 11)
Advances in Plant Biochemistry and Molecular Biology     Full-text available via subscription   (Followers: 7)
Advances in Plant Pathology     Full-text available via subscription   (Followers: 5)
Advances in Porous Media     Full-text available via subscription   (Followers: 5)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 18)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20, SJR: 1.5, h-index: 62)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 6, SJR: 0.478, h-index: 32)
Advances in Radiation Oncology     Open Access  
Advances in Small Animal Medicine and Surgery     Hybrid Journal   (Followers: 3, SJR: 0.1, h-index: 2)
Advances in Space Biology and Medicine     Full-text available via subscription   (Followers: 5)
Advances in Space Research     Full-text available via subscription   (Followers: 370, SJR: 0.606, h-index: 65)
Advances in Structural Biology     Full-text available via subscription   (Followers: 8)
Advances in Surgery     Full-text available via subscription   (Followers: 9, SJR: 0.823, h-index: 27)
Advances in the Study of Behavior     Full-text available via subscription   (Followers: 31, SJR: 1.321, h-index: 56)
Advances in Veterinary Medicine     Full-text available via subscription   (Followers: 16)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 13)
Advances in Virus Research     Full-text available via subscription   (Followers: 6, SJR: 1.878, h-index: 68)
Advances in Water Resources     Hybrid Journal   (Followers: 45, SJR: 2.408, h-index: 94)
Aeolian Research     Hybrid Journal   (Followers: 5, SJR: 0.973, h-index: 22)
Aerospace Science and Technology     Hybrid Journal   (Followers: 338, SJR: 0.816, h-index: 49)
AEU - Intl. J. of Electronics and Communications     Hybrid Journal   (Followers: 8, SJR: 0.318, h-index: 36)
African J. of Emergency Medicine     Open Access   (Followers: 6, SJR: 0.344, h-index: 6)
Ageing Research Reviews     Hybrid Journal   (Followers: 9, SJR: 3.289, h-index: 78)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 432, SJR: 1.385, h-index: 72)
Agri Gene     Hybrid Journal  
Agricultural and Forest Meteorology     Hybrid Journal   (Followers: 15, SJR: 2.18, h-index: 116)
Agricultural Systems     Hybrid Journal   (Followers: 31, SJR: 1.275, h-index: 74)
Agricultural Water Management     Hybrid Journal   (Followers: 42, SJR: 1.546, h-index: 79)
Agriculture and Agricultural Science Procedia     Open Access  
Agriculture and Natural Resources     Open Access   (Followers: 3)
Agriculture, Ecosystems & Environment     Hybrid Journal   (Followers: 56, SJR: 1.879, h-index: 120)
Ain Shams Engineering J.     Open Access   (Followers: 5, SJR: 0.434, h-index: 14)
Air Medical J.     Hybrid Journal   (Followers: 5, SJR: 0.234, h-index: 18)
AKCE Intl. J. of Graphs and Combinatorics     Open Access   (SJR: 0.285, h-index: 3)
Alcohol     Hybrid Journal   (Followers: 11, SJR: 0.922, h-index: 66)
Alcoholism and Drug Addiction     Open Access   (Followers: 8)
Alergologia Polska : Polish J. of Allergology     Full-text available via subscription   (Followers: 1)
Alexandria Engineering J.     Open Access   (Followers: 1, SJR: 0.436, h-index: 12)
Alexandria J. of Medicine     Open Access   (Followers: 1)
Algal Research     Partially Free   (Followers: 9, SJR: 2.05, h-index: 20)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 3)
Allergologia et Immunopathologia     Full-text available via subscription   (Followers: 1, SJR: 0.46, h-index: 29)
Allergology Intl.     Open Access   (Followers: 4, SJR: 0.776, h-index: 35)
Alpha Omegan     Full-text available via subscription   (SJR: 0.121, h-index: 9)
ALTER - European J. of Disability Research / Revue Européenne de Recherche sur le Handicap     Full-text available via subscription   (Followers: 9, SJR: 0.158, h-index: 9)
Alzheimer's & Dementia     Hybrid Journal   (Followers: 49, SJR: 4.289, h-index: 64)
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring     Open Access   (Followers: 4)
Alzheimer's & Dementia: Translational Research & Clinical Interventions     Open Access   (Followers: 4)
Ambulatory Pediatrics     Hybrid Journal   (Followers: 5)
American Heart J.     Hybrid Journal   (Followers: 48, SJR: 3.157, h-index: 153)
American J. of Cardiology     Hybrid Journal   (Followers: 48, SJR: 2.063, h-index: 186)
American J. of Emergency Medicine     Hybrid Journal   (Followers: 42, SJR: 0.574, h-index: 65)
American J. of Geriatric Pharmacotherapy     Full-text available via subscription   (Followers: 9, SJR: 1.091, h-index: 45)
American J. of Geriatric Psychiatry     Hybrid Journal   (Followers: 14, SJR: 1.653, h-index: 93)
American J. of Human Genetics     Hybrid Journal   (Followers: 32, SJR: 8.769, h-index: 256)
American J. of Infection Control     Hybrid Journal   (Followers: 26, SJR: 1.259, h-index: 81)
American J. of Kidney Diseases     Hybrid Journal   (Followers: 31, SJR: 2.313, h-index: 172)
American J. of Medicine     Hybrid Journal   (Followers: 45, SJR: 2.023, h-index: 189)
American J. of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American J. of Obstetrics and Gynecology     Hybrid Journal   (Followers: 208, SJR: 2.255, h-index: 171)
American J. of Ophthalmology     Hybrid Journal   (Followers: 61, SJR: 2.803, h-index: 148)
American J. of Ophthalmology Case Reports     Open Access   (Followers: 6)
American J. of Orthodontics and Dentofacial Orthopedics     Full-text available via subscription   (Followers: 6, SJR: 1.249, h-index: 88)
American J. of Otolaryngology     Hybrid Journal   (Followers: 24, SJR: 0.59, h-index: 45)
American J. of Pathology     Hybrid Journal   (Followers: 27, SJR: 2.653, h-index: 228)
American J. of Preventive Medicine     Hybrid Journal   (Followers: 26, SJR: 2.764, h-index: 154)
American J. of Surgery     Hybrid Journal   (Followers: 36, SJR: 1.286, h-index: 125)
American J. of the Medical Sciences     Hybrid Journal   (Followers: 12, SJR: 0.653, h-index: 70)
Ampersand : An Intl. J. of General and Applied Linguistics     Open Access   (Followers: 6)
Anaerobe     Hybrid Journal   (Followers: 4, SJR: 1.066, h-index: 51)
Anaesthesia & Intensive Care Medicine     Full-text available via subscription   (Followers: 60, SJR: 0.124, h-index: 9)
Anaesthesia Critical Care & Pain Medicine     Full-text available via subscription   (Followers: 14)
Anales de Cirugia Vascular     Full-text available via subscription  
Anales de Pediatría     Full-text available via subscription   (Followers: 2, SJR: 0.209, h-index: 27)
Anales de Pediatría (English Edition)     Full-text available via subscription  
Anales de Pediatría Continuada     Full-text available via subscription   (SJR: 0.104, h-index: 3)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 4, SJR: 2.577, h-index: 7)
Analytica Chimica Acta     Hybrid Journal   (Followers: 36, SJR: 1.548, h-index: 152)
Analytical Biochemistry     Hybrid Journal   (Followers: 171, SJR: 0.725, h-index: 154)
Analytical Chemistry Research     Open Access   (Followers: 8, SJR: 0.18, h-index: 2)
Analytical Spectroscopy Library     Full-text available via subscription   (Followers: 12)
Anesthésie & Réanimation     Full-text available via subscription   (Followers: 1)
Anesthesiology Clinics     Full-text available via subscription   (Followers: 22, SJR: 0.421, h-index: 40)
Angiología     Full-text available via subscription   (SJR: 0.124, h-index: 9)
Angiologia e Cirurgia Vascular     Open Access  
Animal Behaviour     Hybrid Journal   (Followers: 176, SJR: 1.907, h-index: 126)
Animal Feed Science and Technology     Hybrid Journal   (Followers: 5, SJR: 1.151, h-index: 83)

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Journal Cover Advances in Heterocyclic Chemistry
  [SJR: 0.497]   [H-I: 31]   [9 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 0065-2725
   Published by Elsevier Homepage  [3123 journals]
  • Chapter Two Recent Advances in the Synthesis of Piperidines:
           Functionalization of Preexisting Ring Systems
    • Authors: Gong-Qing Liu; Till Opatz
      Pages: 107 - 234
      Abstract: Publication date: 2018
      Source:Advances in Heterocyclic Chemistry, Volume 125
      Author(s): Gong-Qing Liu, Till Opatz
      The present review focuses on strategies for the construction of piperidines which have appeared in the literature since 2003 through mid-2017. In a preceding chapter (2017AHC191), we summarized synthetic methods involving the construction of the piperidine ring from essentially acyclic starting materials in an intra- or intermolecular manner. The present chapter aims at giving a general overview of decoration or modification of previously generated pyridines or piperidines. The hydrogenation of preformed pyridine or pyridinium rings and introduction of substituents into fully saturated piperidines as well as ring expansion of pyrrolidines to piperidines are the most prevalent methods.

      PubDate: 2018-02-05T16:22:16Z
      DOI: 10.1016/bs.aihch.2017.10.001
      Issue No: Vol. 125 (2018)
       
  • Chapter Three Indazoles: Synthesis and Bond-Forming Heterocyclization
    • Authors: Alaa A. Hassan; Ashraf A. Aly; Hendawy N. Tawfeek
      Pages: 235 - 300
      Abstract: Publication date: 2018
      Source:Advances in Heterocyclic Chemistry, Volume 125
      Author(s): Alaa A. Hassan, Ashraf A. Aly, Hendawy N. Tawfeek
      Indazoles (azaindoles) are heterocyclic compounds structurally related to indoles and can be viewed as indole isosteres. The indazole moiety is a 10-π electron aromatic heterocyclic system. Like the pyrazole, indazole resembles both pyridine and pyrrole and its reactivity reflects this. In this chapter, we have updated the synthesis of indazoles and their reactivity we focus attention on the synthesis this class of compounds.

      PubDate: 2018-02-05T16:22:16Z
      DOI: 10.1016/bs.aihch.2017.10.002
      Issue No: Vol. 125 (2018)
       
  • Chapter Four The Chemistry of Sulfur-Containing [5,5]-Fused Ring Systems
           With a Bridgehead Nitrogen
    • Authors: Frédéric Buron; Marie-Aude Hiebel; Jean-Yves Mérour; Karen Plé; Sylvain Routier
      Pages: 301 - 356
      Abstract: Publication date: 2018
      Source:Advances in Heterocyclic Chemistry, Volume 125
      Author(s): Frédéric Buron, Marie-Aude Hiebel, Jean-Yves Mérour, Karen Plé, Sylvain Routier
      This review deals with the synthesis and chemical functionalization of sulfur- and nitrogen-containing [5,5]-fused ring systems with one nitrogen atom in the bridgehead position and a fixed sulfur atom. With up to three additional nitrogen atoms, there are 21 possible ring structures. Of these, only nine are found reported in the literature in more than an anecdotal manner. These scaffolds play an important role in the design and synthesis of biologically active molecules, and the chemistry of these compounds is rich and varied. Their use in medicinal chemistry has grown exponentially in the past few years, especially in the context of molecular diversity. These scaffolds are also bioisosters of indolizines, imidazopyridazines, and their derivatives.

      PubDate: 2018-02-05T16:22:16Z
      DOI: 10.1016/bs.aihch.2017.10.003
      Issue No: Vol. 125 (2018)
       
  • Series Page
    • Abstract: Publication date: 2018
      Source:Advances in Heterocyclic Chemistry, Volume 125


      PubDate: 2018-02-05T16:22:16Z
       
  • Advances in Heterocyclic Chemistry
    • Abstract: Publication date: 2018
      Source:Advances in Heterocyclic Chemistry, Volume 124


      PubDate: 2018-02-05T16:22:16Z
       
  • Editorial Advisory Board
    • Abstract: Publication date: 2018
      Source:Advances in Heterocyclic Chemistry, Volume 124


      PubDate: 2018-02-05T16:22:16Z
       
  • Diketene a Privileged Synthon in the Synthesis of Heterocycles. Part 2:
           Six-Membered Ring Heterocycles
    • Authors: Bahareh Talaei; Majid M. Heravi
      Abstract: Publication date: Available online 23 December 2017
      Source:Advances in Heterocyclic Chemistry
      Author(s): Bahareh Talaei, Majid M. Heravi
      Diketene is an ideal molecule for use in many organic transformations, since it possesses electrophilic and nucleophilic sites which react with numerous functional groups. Diketene is mostly used as the common starting material for structurally diverse mono-, spiro-, and fused six-membered heterocycles such as lactones, pyrans, pyridines, quinolines, isoquinolines, oxazine, quinoxalines, benzothiazinone, 1,4-thiazidines, and oxazinonethione.

      PubDate: 2017-12-27T00:15:36Z
      DOI: 10.1016/bs.aihch.2017.10.004
       
  • Tautomerism and Structure of Azoles: Nuclear Magnetic Resonance
           Spectroscopy
    • Authors: Lyudmila I. Larina
      Abstract: Publication date: Available online 5 August 2017
      Source:Advances in Heterocyclic Chemistry
      Author(s): Lyudmila I. Larina
      This review provides comprehensive data (from the author's work and the literature) on tautomerism of pyrazoles, imidazoles, 1,2,3- and 1,2,4-triazoles, tetrazoles, benzimidazoles, benzimidazolones, benzotriazoles, and related compounds by multinuclear 1H, 13C, 15N nuclear magnetic resonance (NMR) spectroscopy. Emphasis is given to studies of azoles by multinuclear dynamic NMR spectroscopy because prototropic transformations of almost all azoles in solution proceed so quickly. Quantum-chemical investigations of tautomeric azoles are covered in detail. Critical analysis of literature data on the tautomerism of azoles is presented. Theoretical studies of structure and reactivity of azoles are most intriguing because correct interpretation of their chemical behavior and biological activity depends on an understanding the factors determining relative stability of their tautomers. 15N NMR spectroscopy is the most reliable and fast technique for structural and tautomeric determination of nitrogen-containing heteroaromatic compounds.

      PubDate: 2017-08-28T06:21:52Z
      DOI: 10.1016/bs.aihch.2017.06.003
       
  • Heterocycles Incorporating a Pentacoordinated, Hypervalent Phosphorus Atom
    • Authors: Dorota Krasowska; Patrycja Pokora-Sobczak; Aleksandra Jasiak; Józef Drabowicz
      Abstract: Publication date: Available online 17 July 2017
      Source:Advances in Heterocyclic Chemistry
      Author(s): Dorota Krasowska, Patrycja Pokora-Sobczak, Aleksandra Jasiak, Józef Drabowicz
      This chapter presents the synthesis of heterocycles with a hypervalent, pentacoordinated phosphorus atom. It is divided into two sections. The first is devoted to the preparation of pentavalent, pentacoordinated, hypervalent monocyclic phosphoranes, and their selected interconversions. The second section, concerning bicyclic heterocycles, describes the synthesis and reactivity of all kinds of bicyclic phosphoranes. The phenomenon of chirality for this group of organophosphorus derivatives is also briefly discussed.

      PubDate: 2017-07-23T19:13:10Z
      DOI: 10.1016/bs.aihch.2017.06.002
       
  • Organometallic Complexes of Azines
    • Authors: Alexander P. Sadimenko; Omobola O. Okoh
      Abstract: Publication date: Available online 12 July 2017
      Source:Advances in Heterocyclic Chemistry
      Author(s): Alexander P. Sadimenko, Omobola O. Okoh
      Organometallic complexes of practically unsubstituted (non-chelating) azines and their benzannulated derivatives, possible N-heterocyclic carbenes containing at least one double bond, and boron-, boron–nitrogen, silicon-, tri- and hexaphosphorus analogs of azines are considered in the view of their synthetic availability, coordination modes, and possible application in catalysis and materials chemistry.

      PubDate: 2017-07-23T19:13:10Z
      DOI: 10.1016/bs.aihch.2017.06.001
       
  • 2-Pyridone Methides (2-Methylene-1,2-dihydropyridines) and Benzo-Fused
           Analogs11Part 1 (Adv. Heterocycl. Chem., 122, 141 (2017)) contains
           Sections 1 and 2 (Introduction and Synthesis, resp.), including Schemes
           1–50 (Formulas 1–303) and Tables 1 and 2. Part 2: Structure,
           Reactivity, and Application
    • Authors: Gunther Fischer
      Abstract: Publication date: Available online 21 April 2017
      Source:Advances in Heterocyclic Chemistry
      Author(s): Gunther Fischer
      One main focus of the review (Part 2) is spectral and physicochemical properties of both N-unsubstituted methides and anhydrobases, including tautomerism and stability. In the sections on chemical reactivity, reactions upon the α-position as well as ring formation and transformation are dominant. Finally, recently published applications are reviewed.

      PubDate: 2017-04-24T20:45:29Z
       
  • Advances in Heterocyclic Chemistry
    • Abstract: Publication date: 2017
      Source:Advances in Heterocyclic Chemistry, Volume 123


      PubDate: 2017-04-03T16:58:05Z
       
  • Editorial Advisory Board
    • Abstract: Publication date: 2017
      Source:Advances in Heterocyclic Chemistry, Volume 123


      PubDate: 2017-04-03T16:58:05Z
       
  • Advances in Heterocyclic Chemistry
    • Abstract: Publication date: 2017
      Source:Advances in Heterocyclic Chemistry, Volume 122


      PubDate: 2017-03-20T13:54:36Z
       
  • Editorial Advisory Board
    • Abstract: Publication date: 2017
      Source:Advances in Heterocyclic Chemistry, Volume 122


      PubDate: 2017-03-20T13:54:36Z
       
  • Synthesis and Applications of Thiophene Derivatives as Organic Materials
    • Authors: G. Barbarella; M. Zangoli; F. Di Maria
      Abstract: Publication date: Available online 24 February 2017
      Source:Advances in Heterocyclic Chemistry
      Author(s): G. Barbarella, M. Zangoli, F. Di Maria
      Thiophene-based compounds have acquired increasing importance in materials science and technology, owing to their multiple functional properties, chemical robustness, and versatility. Research studies involving thiophene-based materials are highly interdisciplinary and range from organic electronics, in which the semiconducting properties of these materials are exploited in devices such as thin film field-effect transistors and solar cells, to bioimaging, in which their optical properties are exploited to monitor biological events involving proteins and DNA. Since all fields are concerned with the synthesis of new molecular structures, this chapter also deals with the most recent advances in the synthesis of oligo- and polythiophenes.

      PubDate: 2017-02-24T10:54:36Z
      DOI: 10.1016/bs.aihch.2017.01.001
       
  • The Synthesis and Chemistry of Azolobenzodiazepines
    • Authors: Hemming
      Abstract: Publication date: Available online 8 February 2017
      Source:Advances in Heterocyclic Chemistry
      Author(s): K. Hemming
      Approaches to the synthesis and applications of the azolobenzodiazepines have been reviewed with a particular focus on the imidazo-, pyrrolo-, pyrazolo-, and triazolo-fused systems. The review covers N-arylation, metal-catalyzed coupling processes, radiolabeled synthesis, multicomponent reactions, and the synthesis of biologically active molecules. Key natural products covered are the fuligocandins, the circumdatins, and other pyrrolobenzodiazepines. The review also covers well-known pharmaceutical substances such as flumazenil, midazolam, SJG-136, and alprazolam.

      PubDate: 2017-02-10T13:10:10Z
       
  • A Synopsis of the Properties and Applications of Heteroaromatic Rings in
           Medicinal Chemistry
    • Authors: N.A. Meanwell
      Abstract: Publication date: Available online 9 January 2017
      Source:Advances in Heterocyclic Chemistry
      Author(s): N.A. Meanwell
      Five- and six-membered heteroaromatic rings and their benzo-fused homologues are well established as important structural elements in drug design and are well represented in approved drugs. The key properties of these heterocycles that are of interest to medicinal chemists include lipophilicity, pK a, aromaticity, ionization potential, H-bond acceptor, and H-bond donor (NH, OH, CH) capability, electron withdrawing effects, dipole values, and bond angles. The judicious and productive application of azoles and azines in drug design requires an understanding of the intrinsic physical chemical properties of the individual heterocycles and how these interact with substituents. In this article, the key properties of azole and azine heterocycles are summarized followed by a synopsis of applications where some of these factors play a role in drug–target interactions and/or potency.

      PubDate: 2017-01-15T19:21:36Z
      DOI: 10.1016/bs.aihch.2016.11.002
       
  • Advances in Heterocyclic Chemistry
    • Abstract: Publication date: 2017
      Source:Advances in Heterocyclic Chemistry, Volume 121


      PubDate: 2017-01-06T17:19:45Z
       
  • Editorial Advisory Board
    • Abstract: Publication date: 2017
      Source:Advances in Heterocyclic Chemistry, Volume 121


      PubDate: 2017-01-06T17:19:45Z
       
  • Synthesis of Heterocycles From Amidrazones
    • Authors: A.A. Aly; M. Ramadan; H.M. Fatthy
      Abstract: Publication date: Available online 29 December 2016
      Source:Advances in Heterocyclic Chemistry
      Author(s): A.A. Aly, M. Ramadan, H.M. Fatthy
      Amidrazones have the structure R1NC(R2)=NNHR3. The ease of forming CN and CN bonds is reflected in their extensive use for the preparation of heterocycles. While the terminal nitrogen atom of the hydrazone moiety in amidrazones (CNNH2) is the most powerful nucleophilic center, the other two nitrogen atoms can also act as nucleophiles and thus complete cyclization processes. In this chapter, we update the utility of amidrazones in heterocycles synthesis.

      PubDate: 2017-01-06T17:19:45Z
      DOI: 10.1016/bs.aihch.2016.11.001
       
  • Diketene as Privileged Synthon in the Syntheses of Heterocycles Part 1:
           Four- and Five-Membered Ring Heterocyclesa
    • Authors: M.M. Heravi; B. Talaei
      Abstract: Publication date: Available online 30 November 2016
      Source:Advances in Heterocyclic Chemistry
      Author(s): M.M. Heravi, B. Talaei
      4-Methyleneoxetan-2-one (Diketene or DK) consists of a four-membered lactone ring adjacent to a methylene function. It can be used as a versatile precursor for the syntheses of wide range of heterocycles including fused and spiral biheterocycles. In this chapter, we try to cover the structural features and reactivity of DK, and underscore its applications as a flexible and useful synthon in the syntheses of four- and five-membered heterocycles as well as a wide variety of fused or spiro heterocycles. This chapter as part 1 is divided in accordance with the ring sizes and subdivided according to types, numbers, and arrangements of heteroatoms.

      PubDate: 2016-12-05T16:58:07Z
      DOI: 10.1016/bs.aihch.2016.10.003
       
  • 2-Pyridone Methides (2-Methylene-1,2-dihydropyridines) and Benzo-Fused
           Analogs—Part 1: Synthesis
    • Authors: Fischer
      Abstract: Publication date: Available online 30 August 2016
      Source:Advances in Heterocyclic Chemistry
      Author(s): G. Fischer
      The review (Part 1) deals with the synthesis of 2-pyridone methides and benzo-fused analogs. Methides that are unsubstituted at the nitrogen atom are mainly synthesized from the corresponding pyridine bases by reactions at o- or α-positions, from N-oxides or by ring formation or transformation. N-Substituted so-called anhydrobases mostly originate from quaternary salts either by deprotonation or by reactions at o- or α-positions.

      PubDate: 2016-09-02T19:45:40Z
       
 
 
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