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Publisher: Elsevier   (Total: 3042 journals)

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Showing 1 - 200 of 3042 Journals sorted alphabetically
AASRI Procedia     Open Access   (Followers: 15)
Academic Pediatrics     Hybrid Journal   (Followers: 20, SJR: 1.402, h-index: 51)
Academic Radiology     Hybrid Journal   (Followers: 17, SJR: 1.008, h-index: 75)
Accident Analysis & Prevention     Partially Free   (Followers: 81, SJR: 1.109, h-index: 94)
Accounting Forum     Hybrid Journal   (Followers: 23, SJR: 0.612, h-index: 27)
Accounting, Organizations and Society     Hybrid Journal   (Followers: 27, SJR: 2.515, h-index: 90)
Achievements in the Life Sciences     Open Access   (Followers: 4)
Acta Anaesthesiologica Taiwanica     Open Access   (Followers: 5, SJR: 0.338, h-index: 19)
Acta Astronautica     Hybrid Journal   (Followers: 328, SJR: 0.726, h-index: 43)
Acta Automatica Sinica     Full-text available via subscription   (Followers: 3)
Acta Biomaterialia     Hybrid Journal   (Followers: 25, SJR: 2.02, h-index: 104)
Acta Colombiana de Cuidado Intensivo     Full-text available via subscription  
Acta de Investigación Psicológica     Open Access   (Followers: 2)
Acta Ecologica Sinica     Open Access   (Followers: 8, SJR: 0.172, h-index: 29)
Acta Haematologica Polonica     Free   (SJR: 0.123, h-index: 8)
Acta Histochemica     Hybrid Journal   (Followers: 3, SJR: 0.604, h-index: 38)
Acta Materialia     Hybrid Journal   (Followers: 206, SJR: 3.683, h-index: 202)
Acta Mathematica Scientia     Full-text available via subscription   (Followers: 5, SJR: 0.615, h-index: 21)
Acta Mechanica Solida Sinica     Full-text available via subscription   (Followers: 9, SJR: 0.442, h-index: 21)
Acta Oecologica     Hybrid Journal   (Followers: 9, SJR: 0.915, h-index: 53)
Acta Otorrinolaringologica (English Edition)     Full-text available via subscription   (Followers: 1)
Acta Otorrinolaringológica Española     Full-text available via subscription   (Followers: 3, SJR: 0.311, h-index: 16)
Acta Pharmaceutica Sinica B     Open Access   (Followers: 2)
Acta Poética     Open Access   (Followers: 4)
Acta Psychologica     Hybrid Journal   (Followers: 23, SJR: 1.365, h-index: 73)
Acta Sociológica     Open Access  
Acta Tropica     Hybrid Journal   (Followers: 6, SJR: 1.059, h-index: 77)
Acta Urológica Portuguesa     Open Access  
Actas Dermo-Sifiliograficas     Full-text available via subscription   (Followers: 4)
Actas Dermo-Sifiliográficas (English Edition)     Full-text available via subscription   (Followers: 3)
Actas Urológicas Españolas     Full-text available via subscription   (Followers: 4, SJR: 0.383, h-index: 19)
Actas Urológicas Españolas (English Edition)     Full-text available via subscription   (Followers: 2)
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 5, SJR: 0.141, h-index: 3)
Actualites Pharmaceutiques Hospitalieres     Full-text available via subscription   (Followers: 4, SJR: 0.112, h-index: 2)
Acupuncture and Related Therapies     Hybrid Journal   (Followers: 3)
Ad Hoc Networks     Hybrid Journal   (Followers: 11, SJR: 0.967, h-index: 57)
Addictive Behaviors     Hybrid Journal   (Followers: 15, SJR: 1.514, h-index: 92)
Addictive Behaviors Reports     Open Access   (Followers: 5)
Additive Manufacturing     Hybrid Journal   (Followers: 7, SJR: 1.039, h-index: 5)
Additives for Polymers     Full-text available via subscription   (Followers: 20)
Advanced Drug Delivery Reviews     Hybrid Journal   (Followers: 128, SJR: 5.2, h-index: 222)
Advanced Engineering Informatics     Hybrid Journal   (Followers: 11, SJR: 1.265, h-index: 53)
Advanced Powder Technology     Hybrid Journal   (Followers: 16, SJR: 0.739, h-index: 33)
Advances in Accounting     Hybrid Journal   (Followers: 9, SJR: 0.299, h-index: 15)
Advances in Agronomy     Full-text available via subscription   (Followers: 15, SJR: 2.071, h-index: 82)
Advances in Anesthesia     Full-text available via subscription   (Followers: 25, SJR: 0.169, h-index: 4)
Advances in Antiviral Drug Design     Full-text available via subscription   (Followers: 3)
Advances in Applied Mathematics     Full-text available via subscription   (Followers: 6, SJR: 1.054, h-index: 35)
Advances in Applied Mechanics     Full-text available via subscription   (Followers: 10, SJR: 0.801, h-index: 26)
Advances in Applied Microbiology     Full-text available via subscription   (Followers: 20, SJR: 1.286, h-index: 49)
Advances In Atomic, Molecular, and Optical Physics     Full-text available via subscription   (Followers: 16, SJR: 3.31, h-index: 42)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4, SJR: 2.277, h-index: 43)
Advances in Botanical Research     Full-text available via subscription   (Followers: 3, SJR: 0.619, h-index: 48)
Advances in Cancer Research     Full-text available via subscription   (Followers: 25, SJR: 2.215, h-index: 78)
Advances in Carbohydrate Chemistry and Biochemistry     Full-text available via subscription   (Followers: 9, SJR: 0.9, h-index: 30)
Advances in Catalysis     Full-text available via subscription   (Followers: 5, SJR: 2.139, h-index: 42)
Advances in Cellular and Molecular Biology of Membranes and Organelles     Full-text available via subscription   (Followers: 12)
Advances in Chemical Engineering     Full-text available via subscription   (Followers: 24, SJR: 0.183, h-index: 23)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 10, SJR: 0.665, h-index: 29)
Advances in Chronic Kidney Disease     Full-text available via subscription   (Followers: 10, SJR: 1.268, h-index: 45)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 28, SJR: 0.938, h-index: 33)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 18, SJR: 2.314, h-index: 130)
Advances in Computers     Full-text available via subscription   (Followers: 16, SJR: 0.223, h-index: 22)
Advances in Developmental Biology     Full-text available via subscription   (Followers: 11)
Advances in Digestive Medicine     Open Access   (Followers: 4)
Advances in DNA Sequence-Specific Agents     Full-text available via subscription   (Followers: 5)
Advances in Drug Research     Full-text available via subscription   (Followers: 22)
Advances in Ecological Research     Full-text available via subscription   (Followers: 40, SJR: 3.25, h-index: 43)
Advances in Engineering Software     Hybrid Journal   (Followers: 25, SJR: 0.486, h-index: 10)
Advances in Experimental Biology     Full-text available via subscription   (Followers: 7)
Advances in Experimental Social Psychology     Full-text available via subscription   (Followers: 40, SJR: 5.465, h-index: 64)
Advances in Exploration Geophysics     Full-text available via subscription   (Followers: 3)
Advances in Fluorine Science     Full-text available via subscription   (Followers: 8)
Advances in Food and Nutrition Research     Full-text available via subscription   (Followers: 48, SJR: 0.674, h-index: 38)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 15)
Advances in Genetics     Full-text available via subscription   (Followers: 15, SJR: 2.558, h-index: 54)
Advances in Genome Biology     Full-text available via subscription   (Followers: 12)
Advances in Geophysics     Full-text available via subscription   (Followers: 6, SJR: 2.325, h-index: 20)
Advances in Heat Transfer     Full-text available via subscription   (Followers: 21, SJR: 0.906, h-index: 24)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 8, SJR: 0.497, h-index: 31)
Advances in Human Factors/Ergonomics     Full-text available via subscription   (Followers: 25)
Advances in Imaging and Electron Physics     Full-text available via subscription   (Followers: 2, SJR: 0.396, h-index: 27)
Advances in Immunology     Full-text available via subscription   (Followers: 35, SJR: 4.152, h-index: 85)
Advances in Inorganic Chemistry     Full-text available via subscription   (Followers: 9, SJR: 1.132, h-index: 42)
Advances in Insect Physiology     Full-text available via subscription   (Followers: 3, SJR: 1.274, h-index: 27)
Advances in Integrative Medicine     Hybrid Journal   (Followers: 4)
Advances in Intl. Accounting     Full-text available via subscription   (Followers: 4)
Advances in Life Course Research     Hybrid Journal   (Followers: 8, SJR: 0.764, h-index: 15)
Advances in Lipobiology     Full-text available via subscription   (Followers: 2)
Advances in Magnetic and Optical Resonance     Full-text available via subscription   (Followers: 9)
Advances in Marine Biology     Full-text available via subscription   (Followers: 16, SJR: 1.645, h-index: 45)
Advances in Mathematics     Full-text available via subscription   (Followers: 10, SJR: 3.261, h-index: 65)
Advances in Medical Sciences     Hybrid Journal   (Followers: 6, SJR: 0.489, h-index: 25)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 4, SJR: 1.44, h-index: 51)
Advances in Molecular and Cell Biology     Full-text available via subscription   (Followers: 22)
Advances in Molecular and Cellular Endocrinology     Full-text available via subscription   (Followers: 10)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 7, SJR: 0.324, h-index: 8)
Advances in Nanoporous Materials     Full-text available via subscription   (Followers: 4)
Advances in Oncobiology     Full-text available via subscription   (Followers: 3)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 15, SJR: 2.885, h-index: 45)
Advances in Parallel Computing     Full-text available via subscription   (Followers: 7, SJR: 0.148, h-index: 11)
Advances in Parasitology     Full-text available via subscription   (Followers: 7, SJR: 2.37, h-index: 73)
Advances in Pediatrics     Full-text available via subscription   (Followers: 25, SJR: 0.4, h-index: 28)
Advances in Pharmaceutical Sciences     Full-text available via subscription   (Followers: 13)
Advances in Pharmacology     Full-text available via subscription   (Followers: 15, SJR: 1.718, h-index: 58)
Advances in Physical Organic Chemistry     Full-text available via subscription   (Followers: 7, SJR: 0.384, h-index: 26)
Advances in Phytomedicine     Full-text available via subscription  
Advances in Planar Lipid Bilayers and Liposomes     Full-text available via subscription   (Followers: 3, SJR: 0.248, h-index: 11)
Advances in Plant Biochemistry and Molecular Biology     Full-text available via subscription   (Followers: 8)
Advances in Plant Pathology     Full-text available via subscription   (Followers: 5)
Advances in Porous Media     Full-text available via subscription   (Followers: 4)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 18)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 19, SJR: 1.5, h-index: 62)
Advances in Psychology     Full-text available via subscription   (Followers: 59)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 5, SJR: 0.478, h-index: 32)
Advances in Radiation Oncology     Open Access  
Advances in Small Animal Medicine and Surgery     Hybrid Journal   (Followers: 2, SJR: 0.1, h-index: 2)
Advances in Space Research     Full-text available via subscription   (Followers: 340, SJR: 0.606, h-index: 65)
Advances in Structural Biology     Full-text available via subscription   (Followers: 8)
Advances in Surgery     Full-text available via subscription   (Followers: 6, SJR: 0.823, h-index: 27)
Advances in the Study of Behavior     Full-text available via subscription   (Followers: 30, SJR: 1.321, h-index: 56)
Advances in Veterinary Medicine     Full-text available via subscription   (Followers: 15)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 13)
Advances in Virus Research     Full-text available via subscription   (Followers: 5, SJR: 1.878, h-index: 68)
Advances in Water Resources     Hybrid Journal   (Followers: 43, SJR: 2.408, h-index: 94)
Aeolian Research     Hybrid Journal   (Followers: 5, SJR: 0.973, h-index: 22)
Aerospace Science and Technology     Hybrid Journal   (Followers: 309, SJR: 0.816, h-index: 49)
AEU - Intl. J. of Electronics and Communications     Hybrid Journal   (Followers: 8, SJR: 0.318, h-index: 36)
African J. of Emergency Medicine     Open Access   (Followers: 5, SJR: 0.344, h-index: 6)
Ageing Research Reviews     Hybrid Journal   (Followers: 8, SJR: 3.289, h-index: 78)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 400, SJR: 1.385, h-index: 72)
Agri Gene     Hybrid Journal  
Agricultural and Forest Meteorology     Hybrid Journal   (Followers: 15, SJR: 2.18, h-index: 116)
Agricultural Systems     Hybrid Journal   (Followers: 30, SJR: 1.275, h-index: 74)
Agricultural Water Management     Hybrid Journal   (Followers: 38, SJR: 1.546, h-index: 79)
Agriculture and Agricultural Science Procedia     Open Access  
Agriculture and Natural Resources     Open Access   (Followers: 1)
Agriculture, Ecosystems & Environment     Hybrid Journal   (Followers: 50, SJR: 1.879, h-index: 120)
Ain Shams Engineering J.     Open Access   (Followers: 5, SJR: 0.434, h-index: 14)
Air Medical J.     Hybrid Journal   (Followers: 5, SJR: 0.234, h-index: 18)
AKCE Intl. J. of Graphs and Combinatorics     Open Access   (SJR: 0.285, h-index: 3)
Alcohol     Hybrid Journal   (Followers: 9, SJR: 0.922, h-index: 66)
Alcoholism and Drug Addiction     Open Access   (Followers: 6)
Alergologia Polska : Polish J. of Allergology     Full-text available via subscription   (Followers: 1)
Alexandria Engineering J.     Open Access   (Followers: 1, SJR: 0.436, h-index: 12)
Alexandria J. of Medicine     Open Access  
Algal Research     Partially Free   (Followers: 8, SJR: 2.05, h-index: 20)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 3)
Allergologia et Immunopathologia     Full-text available via subscription   (Followers: 1, SJR: 0.46, h-index: 29)
Allergology Intl.     Open Access   (Followers: 4, SJR: 0.776, h-index: 35)
ALTER - European J. of Disability Research / Revue Européenne de Recherche sur le Handicap     Full-text available via subscription   (Followers: 7, SJR: 0.158, h-index: 9)
Alzheimer's & Dementia     Hybrid Journal   (Followers: 48, SJR: 4.289, h-index: 64)
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring     Open Access   (Followers: 5)
Alzheimer's & Dementia: Translational Research & Clinical Interventions     Open Access   (Followers: 3)
American Heart J.     Hybrid Journal   (Followers: 48, SJR: 3.157, h-index: 153)
American J. of Cardiology     Hybrid Journal   (Followers: 44, SJR: 2.063, h-index: 186)
American J. of Emergency Medicine     Hybrid Journal   (Followers: 36, SJR: 0.574, h-index: 65)
American J. of Geriatric Pharmacotherapy     Full-text available via subscription   (Followers: 6, SJR: 1.091, h-index: 45)
American J. of Geriatric Psychiatry     Hybrid Journal   (Followers: 16, SJR: 1.653, h-index: 93)
American J. of Human Genetics     Hybrid Journal   (Followers: 30, SJR: 8.769, h-index: 256)
American J. of Infection Control     Hybrid Journal   (Followers: 24, SJR: 1.259, h-index: 81)
American J. of Kidney Diseases     Hybrid Journal   (Followers: 34, SJR: 2.313, h-index: 172)
American J. of Medicine     Hybrid Journal   (Followers: 46, SJR: 2.023, h-index: 189)
American J. of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American J. of Obstetrics and Gynecology     Hybrid Journal   (Followers: 179, SJR: 2.255, h-index: 171)
American J. of Ophthalmology     Hybrid Journal   (Followers: 55, SJR: 2.803, h-index: 148)
American J. of Ophthalmology Case Reports     Open Access   (Followers: 2)
American J. of Orthodontics and Dentofacial Orthopedics     Full-text available via subscription   (Followers: 6, SJR: 1.249, h-index: 88)
American J. of Otolaryngology     Hybrid Journal   (Followers: 23, SJR: 0.59, h-index: 45)
American J. of Pathology     Hybrid Journal   (Followers: 24, SJR: 2.653, h-index: 228)
American J. of Preventive Medicine     Hybrid Journal   (Followers: 21, SJR: 2.764, h-index: 154)
American J. of Surgery     Hybrid Journal   (Followers: 33, SJR: 1.286, h-index: 125)
American J. of the Medical Sciences     Hybrid Journal   (Followers: 12, SJR: 0.653, h-index: 70)
Ampersand : An Intl. J. of General and Applied Linguistics     Open Access   (Followers: 5)
Anaerobe     Hybrid Journal   (Followers: 4, SJR: 1.066, h-index: 51)
Anaesthesia & Intensive Care Medicine     Full-text available via subscription   (Followers: 55, SJR: 0.124, h-index: 9)
Anaesthesia Critical Care & Pain Medicine     Full-text available via subscription   (Followers: 9)
Anales de Cirugia Vascular     Full-text available via subscription  
Anales de Pediatría     Full-text available via subscription   (Followers: 2, SJR: 0.209, h-index: 27)
Anales de Pediatría (English Edition)     Full-text available via subscription  
Anales de Pediatría Continuada     Full-text available via subscription   (SJR: 0.104, h-index: 3)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 2, SJR: 2.577, h-index: 7)
Analytica Chimica Acta     Hybrid Journal   (Followers: 38, SJR: 1.548, h-index: 152)
Analytical Biochemistry     Hybrid Journal   (Followers: 160, SJR: 0.725, h-index: 154)
Analytical Chemistry Research     Open Access   (Followers: 8, SJR: 0.18, h-index: 2)
Analytical Spectroscopy Library     Full-text available via subscription   (Followers: 11)
Anesthésie & Réanimation     Full-text available via subscription  
Anesthesiology Clinics     Full-text available via subscription   (Followers: 22, SJR: 0.421, h-index: 40)
Angiología     Full-text available via subscription   (SJR: 0.124, h-index: 9)
Angiologia e Cirurgia Vascular     Open Access  
Animal Behaviour     Hybrid Journal   (Followers: 153, SJR: 1.907, h-index: 126)
Animal Feed Science and Technology     Hybrid Journal   (Followers: 5, SJR: 1.151, h-index: 83)
Animal Reproduction Science     Hybrid Journal   (Followers: 5, SJR: 0.711, h-index: 78)
Annales d'Endocrinologie     Full-text available via subscription   (SJR: 0.394, h-index: 30)
Annales d'Urologie     Full-text available via subscription  
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (SJR: 0.177, h-index: 13)
Annales de Chirurgie de la Main et du Membre Supérieur     Full-text available via subscription  
Annales de Chirurgie Plastique Esthétique     Full-text available via subscription   (Followers: 2, SJR: 0.354, h-index: 22)
Annales de Chirurgie Vasculaire     Full-text available via subscription   (Followers: 1)

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Journal Cover Actas Dermo-Sifiliograficas
  [4 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 0001-7310
   Published by Elsevier Homepage  [3042 journals]
  • Dermatosis eosinofílicas asociadas a procesos hematológicos
    • Authors: S. Lucas-Truyols; B. Rodrigo-Nicolás; C. Lloret-Ruiz; E. Quecedo-Estébanez
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): S. Lucas-Truyols, B. Rodrigo-Nicolás, C. Lloret-Ruiz, E. Quecedo-Estébanez
      La dermatosis caracterizada por eosinofilia tisular que aparece en el contexto de un trastorno hematológico se conoce con el nombre de dermatosis eosinofílica asociada a proceso hematológico, siendo el más frecuente de todos la leucemia linfática crónica. Se trata de una entidad poco frecuente que tiene un amplio espectro morfológico, desde pápulas, nódulos eritematosos o ampollas que simulan picaduras de artrópodo hasta la formación de verdaderas placas de tamaño variable y en las que la histología se caracteriza por la presencia de abundantes eosinófilos. Presentamos 4 nuevos casos diagnosticados en nuestro hospital en los últimos 7 años, 3 de ellos asociados a una leucemia linfática crónica y un cuarto caso asociado a una micosis fungoide. La importancia de conocer esta dermatosis radica en el hecho de que puede indicar una progresión de la enfermedad de base, y así fue en 3 de nuestros pacientes. Dermatosis characterized by tissue eosinophilia arising in the context of hematologic disease is known as eosinophilic dermatosis of hematologic malignancy. The most commonly associated malignancy is chronic lymphocytic leukemia. Eosinophilic dermatosis of hematologic malignancy is a rare condition with a wide variety of clinical presentations, ranging from papules, erythematous nodules, or blisters that simulate arthropod bites, to the formation of true plaques of differing sizes. Histology reveals the presence of abundant eosinophils. We present 4 new cases seen in Hospital Arnau de Vilanova, Valencia, during the past 7 years. Three of these cases were associated with chronic lymphocytic leukemia and 1 with mycosis fungoides. It is important to recognize this dermatosis as it can indicate progression of the underlying disease, as was the case in 3 of our patients.

      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.10.021
       
  • Terapia fotodinámica con azul de metileno en úlceras cutáneas
           infectadas con Pseudomonas aeruginosa y Fusarium spp.
    • Authors: C. Aspiroz; M. Sevil; C. Toyas; Y. Gilaberte
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): C. Aspiroz, M. Sevil, C. Toyas, Y. Gilaberte
      La terapia fotodinámica tiene una importante acción antimicrobiana. Se presentan 2 casos clínicos de úlceras crónicas en las extremidades inferiores sobreinfectadas por hongos y bacterias de difícil manejo, en los que el tratamiento fotodinámico con azul de metileno como fotosensibilizante resultó en la curación clínica y microbiológica. No se presentaron efectos adversos reseñables. La posibilidad de utilizar la terapia fotodinámica con azul de metileno en el manejo de las úlceras crónicas sobreinfectadas constituye una interesante alternativa para reducir el uso de antibióticos y disminuir la aparición de resistencias. Photodynamic therapy (PDT) is a therapeutic modality with significant antimicrobial activity. We present 2 cases of chronic lower limb ulcers in which fungal and bacterial superinfection complicated management. PDT with methylene blue as the photosensitizer led to clinical and microbiological cure with no significant adverse effects. PDT with methylene blue is a valid option for the management of superinfected chronic ulcers, reducing the use of antibiotics and the induction of resistance.
      Graphical abstract image

      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.11.020
       
  • Disfunción cardíaca en la epidermólisis ampollosa
    • Authors: M.T. Villarroel Salcedo
      First page: 498
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): M.T. Villarroel Salcedo


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.03.004
       
  • Micosis fungoide en pacientes pediátricos: un reto diagnóstico
    • Authors: R.I. Belloso
      First page: 499
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): R.I. Belloso


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.02.010
       
  • Consideraciones sobre los análisis de subgrupos en los ensayos
           clínicos
    • Authors: P. Coto-Segura
      First page: 501
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): P. Coto-Segura


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.03.003
       
  • Psoriasis y comorbilidad psiquiátrica: la próxima frontera
    • Authors: J.M. Carrascosa; F. Ballesca
      Pages: 502 - 505
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): J.M. Carrascosa, F. Ballesca


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.04.001
       
  • Psoriasis e hígado graso no alcohólico
    • Authors: J.M. Carrascosa; C. Bonanad; E. Dauden; R. Botella; A. Olveira-Martín
      Pages: 506 - 514
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): J.M. Carrascosa, C. Bonanad, E. Dauden, R. Botella, A. Olveira-Martín
      El hígado graso no alcohólico es la principal causa de enfermedad hepática en nuestro medio. Los pacientes con psoriasis presentan mayor prevalencia y gravedad y peor pronóstico de esta hepatopatía. El vínculo patogénico entre ambas es el estado de inflamación crónica y la resistencia periférica a la insulina, habitual en las comorbilidades asociadas a la psoriasis. Por este motivo, en la evaluación de los pacientes con psoriasis, en particular si existen componentes del síndrome metabólico y se requiere tratamiento sistémico, se recomienda descartar esta posibilidad. La coexistencia de psoriasis e hígado graso no alcohólico, con probable sinergia entre ambos, condiciona las medidas generales que deben recomendarse en estos pacientes y también la estrategia terapéutica, por la potencial hepatotoxicidad de algunos de ellos. En este sentido, algunos de los fármacos convencionales habituales como acitretino, metotrexato o ciclosporina presentan potenciales efectos hepatotóxicos cuya repercusión en cada paciente debe evaluarse de forma individualizada. Los fármacos anti-TNF podrían tener efectos beneficiosos fundamentados en el buen control del proceso inflamatorio y de una mejoría de la resistencia periférica a la insulina. Sin embargo, se han descrito casos de hepatotoxicidad en algunos pacientes. No existe evidencia de efectos beneficiosos o perjudiciales de los fármacos anti p40 o anti IL-17. Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver condition in the West. The prevalence and severity of NAFLD is higher and the prognosis worse in patients with psoriasis. The pathogenic link between psoriasis and NAFLD is chronic inflammation and peripheral insulin resistance, a common finding in diseases associated with psoriasis. NAFLD should therefore be ruled out during the initial evaluation of patients with psoriasis, in particular if they show signs of metabolic syndrome and require systemic treatment. Concomitant psoriasis and NAFLD and the likelihood of synergy between them place limitations on general recommendations and treatment for these patients given the potential for liver toxicity. As hepatotoxic risk is associated with some of the conventional drugs used in this setting (e.g., acitretin, methotrexate, and ciclosporin), patients prescribed these treatments should be monitored as appropriate. Anti-tumor necrosis factor agents hold the promise of potential benefits based on their effects on the inflammatory process and improving peripheral insulin resistance. However, cases of liver toxicity have also been reported in relation to these biologics. No evidence has emerged to suggest that anti-p40 or anti-interleukin 17 agents provide benefits or have adverse effects.
      Graphical abstract image

      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.12.017
       
  • Angiogenesis in Dermatology – Insights of Molecular Mechanisms and
           Latest Developments
    • Authors: N.A. Richarz; A. Boada; J.M. Carrascosa
      Pages: 515 - 523
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): N.A. Richarz, A. Boada, J.M. Carrascosa
      Angiogenesis is the growth of new blood vessels from pre-existing vessels. It is a biological process essential in physiological wound healing or pathological inflammation and tumor growth, which underlies a complex interplay of stimulating and inhibiting signals. Extracellular matrix, cells of innate and adaptive immunity and endothelial cells itself are a major source of angiogenic factors that activate or inhibit specific receptors and consequently influence intracellular signaling pathways. Most inflammatory and neoplastic diseases in dermatology are characterized by excessive angiogenesis, such as psoriasis, atopic dermatitis, as well as melanoma, non-melanoma skin cancer, but also benign vascular neoplasia. In this article we describe current knowledge of angiogenesis and its most relevant mechanisms in different dermatological disorders with particular emphasis on the angiogenic factors (vascular endothelial growth factor) and angiopoietins as a target of current and future directions of anti-angiogenic therapy.

      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.adengl.2016.12.022
       
  • Trasplante de folículos pilosos en úlceras crónicas: un
           nuevo concepto de injerto
    • Authors: M.L. Martínez Martínez; E. Escario Travesedo; F. Jiménez Acosta
      Pages: 524 - 531
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): M.L. Martínez Martínez, E. Escario Travesedo, F. Jiménez Acosta
      Las úlceras venosas crónicas de los miembros inferiores representan un reto terapéutico importante en la práctica clínica diaria, resultando primordial la búsqueda de nuevas alternativas que mejoren la curación de estas heridas. Pese al tratamiento habitual con compresión, desbridamiento y uso de apósitos, muchas úlceras permanecen sin cicatrizar. En estas úlceras que no curan uno de los tratamientos más empleados es el trasplante de injertos cutáneos en sus diversas variantes: pinch grafts, punch grafts, injertos de piel de espesor parcial, injertos de piel de grosor total e injertos elaborados a partir de células cultivadas en laboratorio. En los últimos años numerosos estudios han destacado el importante papel del folículo piloso en el proceso de cicatrización de las heridas cutáneas. Trasladando a la práctica estos conocimientos se han utilizado folículos pilosos del cuero cabelludo en injertos tipo punch que son trasplantados al lecho de las úlceras crónicas para estimular su curación. Los resultados parecen ser mejores que el trasplante tradicional de injertos tipo punch sin pelo, lo cual proporciona nuevas líneas de tratamiento para las úlceras venosas crónicas recalcitrantes. Chronic venous leg ulcers are a major therapeutic challenge in clinical practice, and the search for new approaches to improve wound healing is essential. Many ulcers do not heal with traditional treatment using compression, debridement, and dressings. Skin-grafts variants, such as pinch grafts, punch grafts, split- or full-thickness skin grafts, and grafts derived from cells cultured in the laboratory, are among the most widely used options in ulcers that do not heal. In recent years, numerous studies have brought to our attention the important role of the hair follicle in the healing process of cutaneous wounds. Putting knowledge into practice, hair follicles from the scalp have been used in punch-type grafts transplanted to the base of chronic ulcers to stimulate healing. Results appear to be better than those with traditional hairless punch grafts, opening new lines of treatment for recalcitrant chronic venous ulcers.
      Graphical abstract image

      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.02.013
       
  • Miocardiopatía en pacientes con epidermólisis ampollosa
           hereditaria
    • Authors: A. Batalla; A. Vicente; J. Bartrons; F. Prada; C. Fortuny; M.A. González-Enseñat
      Pages: 544 - 549
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): A. Batalla, A. Vicente, J. Bartrons, F. Prada, C. Fortuny, M.A. González-Enseñat
      Introducción y objetivos En las últimas décadas se ha descrito la asociación entre epidermólisis ampollosa (EA) y miocardiopatía dilatada (MD). Generalmente esta última enfermedad se detecta en fases avanzadas, implicando un peor pronóstico. Nuestro objetivo consistió en determinar la prevalencia de MD en los pacientes con EA vistos en el Hospital San Joan de Déu (Barcelona) desde mayo de 1986 a abril de 2015. Métodos Estudio descriptivo transversal mediante revisión de las historias clínicas con atención al tipo y subtipos mayores de EA y la existencia o no de MD. Resultados Se recogieron 57 pacientes con diagnóstico de EA. De ellos 19 presentaban EA simple, 10 EA juntural, 27 EA distrófica (14 EA distrófica dominante y 13 EA distrófica recesiva) y existió un caso de síndrome de Kindler. Solo 2 de los pacientes con EA distrófica recesiva presentaron MD. En 23 de los pacientes con EA existieron factores que podrían tener una relación causal con el potencial desarrollo de MD. Conclusión La MD puede ser una complicación en los pacientes con EA, mayoritariamente del subtipo de EA distrófica recesiva, por lo que deben hacerse controles periódicos para su temprano diagnóstico y tratamiento. Introduction and objective In recent decades, an association has been reported between epidermolysis bullosa (EB) and dilated cardiomyopathy (DC). DC is typically in an advanced phase when detected, leading to a poorer prognosis. Our objective was to determine the prevalence of DC in patients with EB seen in Hospital San Joan de Déu in Barcelona, Spain, between May 1986 and April 2015. Methods This was a descriptive, cross-sectional chart-review study in which we recorded the type and main subtypes of EB and the presence or absence of DC. Results Fifty-seven patients with EB were found, 19 with EB simplex, 10 with junctional EB, 27 with dystrophic EB (14 dominant dystrophic and 13 recessive dystrophic), and just 1 with Kindler syndrome. DC was detected in only 2 patients with recessive dystrophic EB. Twenty-three patients had presented factors that could have had a causal relationship with the potential onset of DC. Conclusion DC is a possible complication of EB, particularly in recessive dystrophic EB. Periodic follow-up should be performed to make an early diagnosis and start treatment.
      Graphical abstract image

      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.01.015
       
  • Comparison of ixekizumab with etanercept or placebo in moderate-to-severe
           psoriasis: Subgroup analysis of Latin American patients in the phase 3
           randomized UNCOVER-3 study
    • Authors: F. Valenzuela; C. de la Cruz Fernandez; R.L. Galimberti; S. Gürbüz; M. McKean-Matthews; L. Goncalves; R. Romiti
      Pages: 550 - 563
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): F. Valenzuela, C. de la Cruz Fernandez, R.L. Galimberti, S. Gürbüz, M. McKean-Matthews, L. Goncalves, R. Romiti
      Background and objectives Ixekizumab demonstrated greater efficacy than placebo and etanercept in UNCOVER-3. Subgroup analysis of Latin American patients was performed. We report 12-week and 60-week data. Patients and methods Analysis included 102 Latin American patients randomized to receive placebo (n =14), etanercept 50mg twice weekly (n =30), or ixekizumab 160-mg starting dose followed by 80mg every 2 weeks (Q2W; n =29) or every 4 weeks (Q4W; n =29). At week 12, patients maintaining efficacy response and adequate overall safety were assigned, at the discretion of the investigator, to long-term extension with ixekizumab Q4W. Results At week 12, Psoriasis Area and Severity Index (PASI) 100 scores were 0%, 20.0% (p =0.075 vs placebo), 62.1% (p <0.001 vs placebo; p =0.001 vs etanercept), and 48.3% (p =0.002 vs placebo; p =0.023 vs etanercept) for placebo, etanercept, ixekizumab Q2W, and ixekizumab Q4W, respectively. Among patients who continued therapy up to week 60 (n =97), PASI 100 scores were 71.4%, 60.0%, 77.8%, and 57.7% for patients who received induction placebo, etanercept, ixekizumab Q2W, and ixekizumab Q4W, respectively (non-responder imputation). By week 60, ≥1 serious adverse event was experienced by 7.1% (n =1/14), 3.3% (n =1/30), 14.8% (n =4/27), and 0% (n =0/26) of patients who received induction placebo, etanercept, ixekizumab Q2W, and ixekizumab Q4W, respectively. There were no cases of active tuberculosis with ixekizumab treatment through 60 weeks. Conclusions In Latin American patients, both ixekizumab dosing regimens demonstrated greater efficacy than etanercept for treating psoriasis over 12 weeks. The safety profile of ixekizumab through 60 weeks was well tolerated and consistent with the overall profile.
      Graphical abstract image

      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.adengl.2017.02.026
       
  • Micosis fungoide. Experiencia en un hospital pediátrico
    • Authors: A.B. Cervini; A.N. Torres-Huamani; C. Sanchez-La-Rosa; L. Galluzzo; V. Solernou; J. Digiorge; P. Rubio
      Pages: 564 - 570
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): A.B. Cervini, A.N. Torres-Huamani, C. Sanchez-La-Rosa, L. Galluzzo, V. Solernou, J. Digiorge, P. Rubio
      La micosis fungoide (MF) es el linfoma cutáneo primario de células T más frecuente. Su aparición en la infancia es excepcional. Objetivos Describir las características epidemiológicas, clínicas, histopatológicas e inmunofenotípicas de los pacientes con MF. Describir los tratamientos utilizados y la evolución. Material y método Se incluyeron todos los pacientes admitidos en el Hospital de Pediatría Dr. J. P. Garrahan (Argentina) en el período comprendido entre agosto de 1988 y julio de 2014 con diagnóstico clínico e histopatológico de MF. Resultados Se diagnosticaron 14 pacientes con MF. La distribución por sexo fue M/F: 1:1,33. La edad media al diagnóstico fue de 11,23 años (rango: 8 a 15 años). El tiempo promedio de evolución hasta el momento del diagnóstico fue de 3 años y 6 meses (rango: 4 meses a 7 años). Todos los pacientes presentaron la forma clínica hipopigmentada y en el 42% se asoció la forma clásica. El 50% (n=7) exhibió un inmunofenotipo CD8 positivo de forma exclusiva. El 78% presentó estadio IB. La fototerapia fue el tratamiento de elección. Cuatro pacientes tuvieron por lo menos una recaída y 3 demostraron progresión de su enfermedad a nivel cutáneo. La evolución fue favorable en todos los casos. Conclusiones La MF es una entidad infrecuente en la infancia, siendo la forma hipopigmentada la más frecuente. Su diagnóstico es tardío debido a la similitud con otras enfermedades hipopigmentadas frecuentes en la niñez. A pesar de tener un buen pronóstico, presenta alta tasa de recidivas y requiere un seguimiento a largo plazo. Mycosis fungoides (MF), the most common primary cutaneous T-cell lymphoma, is unusual in children. Objectives We aimed to describe the epidemiologic, clinical, histopathologic, and immunophenotypic characteristics of MF as well as treatments and course of disease in a pediatric case series. Material and method Data for all patients admitted to our pediatric hospital (Hospital Dr. J. P. Garrahan) in Argentina with a clinical and histopathologic diagnosis of MF between August 1988 and July 2014 were included. Results A total of 14 patients were diagnosed with MF. The ratio of boys to girls was 1:1.33. The mean age at diagnosis was 11.23 years (range, 8–15 years). The mean time between onset and diagnosis was 3.5 years (range, 4 months–7 years). All patients had hypopigmented MF and 42% also presented the features of classic MF. Seven (50%) had the CD8+ immunophenotype exclusively. Seventy-eight percent were in stage IB at presentation. Phototherapy was the treatment of choice. Four patients relapsed at least once and skin lesions progressed in 3 patients. All patients improved. Conclusions MF is unusual in children. The hyp...
      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.01.008
       
  • Dermatitis alérgica de contacto pediátrica. Estudio
           clínico-epidemiológico en un hospital terciario
    • Authors: J.M. Ortiz Salvador; A. Esteve Martínez; D. Subiabre Ferrer; A.M. Victoria Martínez; J. de la Cuadra Oyanguren; V. Zaragoza Ninet
      Pages: 571 - 578
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): J.M. Ortiz Salvador, A. Esteve Martínez, D. Subiabre Ferrer, A.M. Victoria Martínez, J. de la Cuadra Oyanguren, V. Zaragoza Ninet
      Introducción Los estudios epidemiológicos sobre incidencia de dermatitis alérgica de contacto en población pediátrica son escasos. Algunos trabajos consideran que se trata de una entidad infradiagnosticada, y que en muchos casos no se sospecha clínicamente, no realizándose pruebas epicutáneas. No obstante se han comunicado tasas prevalencia de hasta el 20% de sensibilización a alérgenos en la población pediátrica, por lo que probablemente debería ser tenida en cuenta como una posibilidad diagnóstica en este grupo de edad. Material y método Se ha realizado un análisis retrospectivo de la base de datos de alergia cutánea del servicio de Dermatología del Hospital General seleccionando los casos diagnosticados en niños de entre 0 y 16 años durante los últimos 15 años (año 2000 hasta 2015). El estudio incluye variables epidemiológicas (edad, sexo, antecedentes de atopia) y clínicas (localización de las lesiones, baterías de alérgenos empleadas, alérgenos positivos y su relevancia). Resultados De los 4.593 pacientes estudiados con pruebas epicutáneas en los últimos 15 años, 265 (6%) correspondían a niños de 0-16 años. Ciento cuarenta y cuatro pacientes (54,3%) mostraron positividad para al menos uno de los alérgenos parcheados. Los alérgenos más frecuentemente identificados fueron en orden decreciente: tiomersal, cloruro de cobalto, colofonia, parafenilendiamina, dicromato potásico, mercurio y níquel. La sensibilización fue considerada de relevancia presente en 177 casos (61,3%). Conclusión Más de la mitad de los niños estudiados mostraron sensibilización a uno o más alérgenos, con un porcentaje importante de sensibilizaciones relevantes. Todo niño con sospecha clínica de dermatitis alérgica de contacto debería ser remitido para realización de pruebas epicutáneas. Al no existir pruebas estandarizadas en este colectivo se requiere un alto nivel de sospecha clínica y un conocimiento de los alérgenos más frecuentemente implicados de cara a seleccionar los alérgenos a parchar. Background Few epidemiological studies have investigated the incidence of allergic contact dermatitis in children. Underdiagnosis has been observed in some studies, with many cases in which the condition is not suspected clinically and patch tests are not performed. However, the prevalence of pediatric sensitization to allergens has been reported to be as high as 20%, and the diagnosis should therefore be contemplated as a possibility in this age group. Material and methods We performed a retrospective analysis of the skin allergy database of the Dermatology Department of Consorcio Hospital General Universitario de Valencia. Children between 0 and 16 years of age diagnosed with allergic contact dermatitis in the previous 15 years (between 2000 and 2015) were included in the analysis. Epidemiological (age, sex, history of atopy) and clinical (site of the lesions, allergen series applied, positive reactions, and their relevance) variables were gathered. Results Patch tests had been performed on 4,593 patients during the study period. Of these, 265 (6%) were children aged between 0 and 16 years. A positive reaction to at least one of the allergens tested was observed in 144 (54.3%) patients in that group. The allergens most frequently identified were the following (in decreasing order of frequency): thiomersal, cobalt chloride, colophony, paraphenylenediamin...
      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.12.018
       
  • Múltiples pápulas en ambas manos
    • Authors: A. Panés-Rodríguez; A. Jaka-Moreno; I. Arias-Camisón Montero; A. Tuneu-Valls
      Pages: 579 - 580
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): A. Panés-Rodríguez, A. Jaka-Moreno, I. Arias-Camisón Montero, A. Tuneu-Valls


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.02.023
       
  • Nódulo en el pabellón auricular
    • Authors: S. Heras-González; L. Aspe-Unanue; R. González-Pérez
      Pages: 581 - 582
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): S. Heras-González, L. Aspe-Unanue, R. González-Pérez


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.02.022
       
  • FR-Pulsos de itraconazol en dermatitis seborreica. Una opción
           terapéutica a tener en cuenta
    • Authors: V. Fatsini-Blanch; M.I. Martínez-González; S. Heras-González; A. de Quintana-Sancho
      Pages: 583 - 584
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): V. Fatsini-Blanch, M.I. Martínez-González, S. Heras-González, A. de Quintana-Sancho


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.01.006
       
  • Hiperplasia angiolinfoide con eosinofilia
    • Authors: M.D. Nakandakari; D.N. de la Rosa; J. Arias
      First page: 586
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): M.D. Nakandakari, D.N. de la Rosa, J. Arias


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.02.021
       
  • Herpes zóster diseminado posvacunal en un niño sano
    • Authors: J.M. Rueda; M. Feito-Rodríguez; D. Nieto; R. de Lucas-Laguna
      Pages: 587 - 588
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): J.M. Rueda, M. Feito-Rodríguez, D. Nieto, R. de Lucas-Laguna


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.12.013
       
  • Úlcera crónica en paciente con trasplante renal
    • Authors: A. Pulpillo Ruiz
      Pages: 589 - 590
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): A. Pulpillo Ruiz


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.11.017
       
  • Eritema nudoso como reacción de hipersensibilidad a la azatioprina
    • Authors: M. González-Olivares; R. Khedaoui; C. Martínez-Morán; J. Borbujo
      Pages: 591 - 593
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): M. González-Olivares, R. Khedaoui, C. Martínez-Morán, J. Borbujo


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.12.006
       
  • Refractory solar urticaria successfully treated with omalizumab with
           normalization of phototest
    • Authors: A. Combalia; C. Fernández-Sartorio; P. Aguilera
      Pages: 593 - 594
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): A. Combalia, C. Fernández-Sartorio, P. Aguilera


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.adengl.2016.11.020
       
  • Estudio multicéntrico sobre el uso de oxibutinina oral en
           hiperhidrosis local y multifocal
    • Authors: T. Toledo-Pastrana; J. Márquez-Enríquez; J.F. Millán-Cayetano
      Pages: 597 - 599
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): T. Toledo-Pastrana, J. Márquez-Enríquez, J.F. Millán-Cayetano


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.11.013
       
  • Sorafenib-induced Acute Generalized Exanthematous Pustulosis: An
           Increasing Association'
    • Authors: A. Alegre-Sánchez; D. de Perosanz-Lobo; I. Pinilla-Pagnon; E. Muñoz-Zato
      Pages: 599 - 601
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): A. Alegre-Sánchez, D. de Perosanz-Lobo, I. Pinilla-Pagnon, E. Muñoz-Zato


      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2016.11.018
       
  • Los nuevos sistemas de estadificación del AJCC incorporan novedades en el
           cáncer cutáneo
    • Abstract: Publication date: Available online 18 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): J. Cañueto, C. Román-Curto
      Cuarenta años después de la publicación de la primera edición de la estadificación del American Joint Committee on Cancer, la octava edición se publica con cambios relevantes en el cáncer de piel. En el cáncer cutáneo no melanoma el American Joint Committee on Cancer mantiene un enfoque específico para el carcinoma de células de Merkel y tiene en cuenta algunos trabajos publicados recientemente sobre el pronóstico del carcinoma epidermoide cutáneo en la definición de una categoría T completamente nueva para este tumor. Por otra parte, la estadificación se contempla para el carcinoma epidermoide cutáneo de cabeza y cuello (excluyendo el párpado) y en otras localizaciones; únicamente ofrece soluciones para la estratificación de tumores de vulva, pene y región perineal. En relación con el melanoma, el valor del índice mitótico desaparece y el pronóstico del tumor primario se define basándose en el espesor de Breslow y la ulceración. Además, el espesor pasa a registrarse con una precisión de 0,1mm y aparece el concepto de T0 para los melanomas metastásicos en los que el primario ha regresado completamente. Existen diferencias en la categoría N de todos los sistemas de estadificación de cáncer cutáneo en esta nueva edición, y en relación con la categoría M, en el melanoma aparece la categoría M1d para hacer referencia a la afectación metastásica del SNC, que hasta el momento se incluía dentro de la categoría M1c. Será necesario validar este nuevo sistema con series de pacientes para valorar si efectivamente cumple con el objetivo de estratificar por riesgo los tumores de una manera adecuada. The eighth edition of the staging manual of the American Joint Committee on Cancer incorporates important changes in the classification of skin cancers. Coming 40 years after the first edition, the latest manual preserves its specific system for Merkel cell carcinoma and takes into account recent publications on the prognosis of squamous cell carcinoma by defining a completely new T category for this neoplasm. Staging for squamous cell carcinoma considers head and neck tumors (excluding the eyelid) and does not offer solutions for other sites except the vulva, penis, and perianal region. Regarding melanoma, use of the mitotic index has been eliminated and the prognosis of the primary tumor is based on Breslow thickness and ulceration. In addition, thickness is now recorded to an accuracy of 0.1mm, and the T0 concept has been introduced to define those metastatic melanomas in which the primary tumor has regressed completely. In this new edition, changes have also been made to the N category of all the skin cancer staging systems, and M1d has been added to the M category for melanoma to refer to metastatic involvement of the central nervous system, which, up to now, had been included in the M1c category. This new system will need to be validated with patient series to determine if it adequately satisfies the objective of tumor risk stratification.

      PubDate: 2017-07-22T07:35:42Z
       
  • Síndrome de Schnitzler con respuesta a anakinra en monoterapia: 7
           años de seguimiento
    • Authors: Y. Hidalgo-García; E. García-Fernández; L. Palacio-Aller; P. Gonzalvo
      Abstract: Publication date: Available online 17 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): Y. Hidalgo-García, E. García-Fernández, L. Palacio-Aller, P. Gonzalvo


      PubDate: 2017-07-22T07:35:42Z
      DOI: 10.1016/j.ad.2017.03.015
       
  • Carcinoma mucinoso primario cutáneo: presentación de un caso
    • Authors: C. Areán-Cuns; A. Córdoba-Iturriagagoitia; B. Aguiar-Losada; I. Yanguas-Bayona
      Abstract: Publication date: Available online 17 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): C. Areán-Cuns, A. Córdoba-Iturriagagoitia, B. Aguiar-Losada, I. Yanguas-Bayona


      PubDate: 2017-07-22T07:35:42Z
      DOI: 10.1016/j.ad.2017.03.013
       
  • Granuloma anular posiblemente secundario a la ingesta de topiramato
    • Authors: S. Heras-González; T. Piqueres-Zubiaurre; A. Martínez de Salinas-Quintana; R. González-Pérez
      Abstract: Publication date: Available online 13 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): S. Heras-González, T. Piqueres-Zubiaurre, A. Martínez de Salinas-Quintana, R. González-Pérez


      PubDate: 2017-07-22T07:35:42Z
      DOI: 10.1016/j.ad.2017.03.016
       
  • Tratamiento de la hiperhidrosis palmar con toxina botulínica mediante
           bloqueo de los nervios periféricos al nivel de la muñeca
    • Authors: A. de Quintana-Sancho; M.T. Conde Calvo
      Abstract: Publication date: Available online 12 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): A. de Quintana-Sancho, M.T. Conde Calvo


      PubDate: 2017-07-22T07:35:42Z
      DOI: 10.1016/j.ad.2017.05.013
       
  • Concordancia mutacional de BRAF entre melanoma primario cutáneo y sus
           correspondientes metástasis. Revisión de la evidencia actual
    • Authors: E. Godoy-Gijón; M. Yuste-Chaves; Á. Santos-Briz
      Abstract: Publication date: Available online 12 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): E. Godoy-Gijón, M. Yuste-Chaves, Á. Santos-Briz
      La mutación en el oncogén BRAF en melanoma y la aparición de terapias dirigidas frente a ella han supuesto un antes y un después en el tratamiento de esta enfermedad. El estudio del estado mutacional en las metástasis y su concordancia con el tumor primario tiene además una gran implicación terapéutica en estos pacientes, pues permite seleccionar candidatos a estos tratamientos. El objetivo de esta revisión es conocer las evidencias disponibles sobre el grado de concordancia en los distintos tipos de metástasis en el melanoma cutáneo, así como las ventajas y desventajas de los distintos métodos de detección de la mutación en BRAF. Identification of the BRAF oncogene mutation and the emergence of BRAF-targeted therapy marked a turning point in the treatment of melanoma. The study of mutation status concordance between primary tumors and metastases in this cancer has major treatment implications as it facilitates the selection of candidates for targeted therapy. The aim of this study was to review the evidence on the level of mutation status concordance between primary tumors and different types of metastases in cutaneous melanoma and to provide an overview of the advantages and disadvantages of the various methods used to detect the BRAF mutation.
      Graphical abstract image

      PubDate: 2017-07-22T07:35:42Z
      DOI: 10.1016/j.ad.2016.12.025
       
  • Acantomas epidermolíticos múltiples del escroto: lo que el
           prurito genital puede esconder
    • Authors: P. García-Martínez; L. Curto-Barredo; R. Rovira-López; R.M. Pujol
      Abstract: Publication date: Available online 11 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): P. García-Martínez, L. Curto-Barredo, R. Rovira-López, R.M. Pujol


      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.03.017
       
  • Malformación capilar adquirida (síndrome de Fegeler): 3 casos
    • Authors: J.F. Millán-Cayetano; J. del Boz; P. García-Montero; M. de Troya-Martín
      Abstract: Publication date: Available online 11 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): J.F. Millán-Cayetano, J. del Boz, P. García-Montero, M. de Troya-Martín


      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.02.028
       
  • Dermoscopy of Pigmented Actinic Keratosis of the Face: A Study of 232
           Cases
    • Authors: A. Kelati; H. Baybay; E. Moscarella; G. Argenziano; S. Gallouj; F.Z. Mernissi
      Abstract: Publication date: Available online 11 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): A. Kelati, H. Baybay, E. Moscarella, G. Argenziano, S. Gallouj, F.Z. Mernissi
      The diagnosis of pigmented actinic keratosis (PAK) is often challenging because of overlapping features with lentigo maligna. Objective To investigate dermoscopic patterns of PAK according to their different evolutionary stages, and to correlate the pattern with clinical characteristics of the patients. Methods Descriptive and analytical study of 232 PAK. Dermoscopic patterns were divided into two categories: the follicule surroundings’ abnormalities (FSA) and follicular keratosis’ abnormalities (FKA). Results FSA and FKA dermoscopic patterns were related to male gender, except for star-like appearance, double white clods and dermoscopic horn (p ≤0.04). Rhomboidal, annular granular pattern, gray halo, white circle and double clods were dermoscopic pattern significantly related to xeroderma pigmentosum's type of skin. Based on the evolutionary stages of PAK, the jelly sign was significantly related to thin patches of PAK. Central crusts and scales were related to thick plaques and the star-like appearance to hypertrophic PAK. The presence of 2 or more dermoscopic signs in both FSA and FKA was noticed in 99.1% of lesions. Conclusions The dermoscopic diagnosis of PAK vary according to the evolutionary stages of the disease, this will increase the diagnosis accuracy, with therapeutic implications.
      Graphical abstract image

      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.05.002
       
  • Liquen aureus: ¿un caso congénito'
    • Authors: O. Corral Magaña; J. Escalas Taberner; A. Bauzá Alonso; A. Martin-Santiago
      Abstract: Publication date: Available online 11 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): O. Corral Magaña, J. Escalas Taberner, A. Bauzá Alonso, A. Martin-Santiago


      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.04.023
       
  • Vacuna triple vírica como tratamiento de verruga subungueal
           recalcitrante
    • Authors: C. Morales-Raya; L. Maroñas-Jiménez; R. Aragón-Miguel; C. Postigo-Llorente
      Abstract: Publication date: Available online 11 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): C. Morales-Raya, L. Maroñas-Jiménez, R. Aragón-Miguel, C. Postigo-Llorente


      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.02.030
       
  • Pápulas umbilicadas en los codos en una paciente con una vasculitis
           sistémica
    • Authors: C. Lloret-Ruiz; N. Barrado-Solís; E. Quecedo-Estébanez
      Abstract: Publication date: Available online 11 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): C. Lloret-Ruiz, N. Barrado-Solís, E. Quecedo-Estébanez


      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.02.024
       
  • Lupus eritematoso con afectación genital: una localización
           inusual
    • Authors: E. del Alcázar-Viladomiu; A. López-Pestaña; A. Tuneu-Valls
      Abstract: Publication date: Available online 11 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): E. del Alcázar-Viladomiu, A. López-Pestaña, A. Tuneu-Valls


      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.05.010
       
  • Reacción local intensa en zonas de inyección de mesoterapia
           lipolítica
    • Authors: S. Córdoba; E. Rojas; A. Garrido-Ríos; J. Borbujo
      Abstract: Publication date: Available online 11 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): S. Córdoba, E. Rojas, A. Garrido-Ríos, J. Borbujo


      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.02.027
       
  • El dermatólogo y el cáncer de piel. Consideraciones sobre el
           posicionamiento de la Sociedad Española de Oncología Médica
    • Authors: D. Moreno-Ramírez; E. Nagore; R. Botella-Estrada; G. Carretero; S. Puig; P. Redondo; M.A. Rodrígurez-Prieto; E. Samaniego; O. Sanmartín; J. Malvehy
      Abstract: Publication date: Available online 10 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): D. Moreno-Ramírez, E. Nagore, R. Botella-Estrada, G. Carretero, S. Puig, P. Redondo, M.A. Rodrígurez-Prieto, E. Samaniego, O. Sanmartín, J. Malvehy


      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.06.003
       
  • Utilidad de la ecografía en el diagnóstico y seguimiento del
           pioderma gangrenoso
    • Authors: Aliste
      Abstract: Publication date: Available online 10 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): M. Pousa-Martínez, D. Sánchez-Aguilar, C. Aliste, H. Vázquez-Veiga


      PubDate: 2017-07-12T07:28:30Z
       
  • Reconstrucción de defecto en cuero cabelludo mediante doble colgajo
           en hacha
    • Authors: A. Varela-Veiga; O. Suárez-Magdalena; Ó. Suárez-Amor; B. Monteagudo
      Abstract: Publication date: Available online 6 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): A. Varela-Veiga, O. Suárez-Magdalena, Ó. Suárez-Amor, B. Monteagudo


      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.04.019
       
  • ¿Es útil la determinación de la dosis eritematógena mínima previa a
           la fototerapia ultravioleta B de banda estrecha'
    • Authors: M.T. Rodríguez-Granados; A. Estany-Gestal; M. Pousa-Martínez; J. Labandeira; R. Gato Otero; V. Fernández-Redondo
      Abstract: Publication date: Available online 4 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): M.T. Rodríguez-Granados, A. Estany-Gestal, M. Pousa-Martínez, J. Labandeira, R. Gato Otero, V. Fernández-Redondo
      Introducción y objetivos La dosis de inicio en la fototerapia UVB de banda estrecha (UVBBE) viene determinada por el fototipo o por la determinación de la dosis eritematógena mínima (DEM). El cálculo de la DEM identifica pacientes con fotosensibilidad no sospechada. El objetivo de nuestro estudio es conocer la influencia que puedan tener en una DEM disminuida los fármacos fotosensibilizantes concomitantes, el diagnóstico, la asociación con acitretina en pacientes con psoriasis y evidenciar si la DEM alterada provoca más reacciones adversas y más graves. Material y métodos Se trata de un estudio observacional de una cohorte retrospectiva desde el período comprendido entre el 1 de febrero de 2009 al 31 de marzo de 2015. La determinación de la DEM se categorizó en DEM normal o patológica. Resultados Trescientos dos pacientes con distintas dermatosis inician UVBBE en función de la DEM. No se han encontrado diferencias entre el grupo con DEM patológica respecto al normal, ni en el número de fármacos consumidos (p=0,071), ni en el potencial fotosensibilizante (p=0,806). El análisis multivariante ajustado por edad, sexo y fototipo reveló que la psoriasis es un factor protector de DEM patológica (OR=0,31 [IC 95%: 0,16-0,58]). No se encontró riesgo significativo de eritema ni prurito en los pacientes con DEM alterada OR=1,68 (IC 95%: 0,91-3,29) y OR=2,04 (IC 95%: 0,99-4,22), respectivamente. Conclusiones La psoriasis protege de tener una DEM patológica. Si bien el eritema y el prurito fueron más frecuentes en los pacientes con DEM patológica, las diferencias no fueron estadísticamente significativas. Introduction and objectives The starting dose for narrowband UV-B phototherapy is determined by a patient's skin phototype or minimal erythema dose (MED). Calculation of MED identifies patients with unsuspected photosensitivity. The aim of this study was to investigate the influence of factors such as concomitant use of photosensitizing agents, diagnosis, and combination with acitretin in patients with psoriasis on the frequency and severity of adverse effects in patients with a low MED to narrowband UV-B phototherapy. Material and methods We undertook a retrospective observational cohort study between February 1, 2009 and March 31, 2015. MED values were classified as normal or low. Results In total, 302 patients with different skin conditions started narrowband UV-B phototherapy at a dose determined by their MED. No differences were found between patients with a low MED and those with a normal MED for number of drugs taken (P =.071) or use of photosensitizing agents (P =0.806). Following adjustment for age, sex, and phototype, the multivariate analysis showed that psoriasis exerted a protective effect against a low MED (OR=0.31 [95% CI, 0.16-0.58]). No significant risk of erythema or pruritus was detected in patients with a low MED (OR=1.68; 95% CI, 0.91-3.29 and OR=2.04; 95% CI, 0.99-4.22, respectively). ...
      PubDate: 2017-07-12T07:28:30Z
      DOI: 10.1016/j.ad.2017.05.009
       
  • Virus Zika: manifestaciones cutáneas en 3 pacientes
    • Authors: A. Cosano-Quero; V. Velasco-Tirado; M.P. Sánchez Seco; L. Manzanedo-Bueno; M. Belhassen-García
      Abstract: Publication date: Available online 3 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): A. Cosano-Quero, V. Velasco-Tirado, M.P. Sánchez Seco, L. Manzanedo-Bueno, M. Belhassen-García
      La infección por el virus Zika debe sospecharse en viajeros o inmigrantes con clínica de viriasis (exantema, fiebre, artralgias, artritis, conjuntivitis, cefalea, etc.) y una historia epidemiológica compatible. Aunque las manifestaciones cutáneas se encuentran entre las más frecuentes no son específicas y su iconografía es escasa. Presentamos 3 casos, 2 viajeros y un inmigrante que comienzan con un exantema por virus Zika. Alcanzar el diagnóstico de forma rápida optimiza el manejo de estos pacientes, mejora el control de los casos graves y permite minimizar una posible transmisión autóctona dado el riesgo que supone la presencia del Aedes albopictus como potencial vector transmisor de esta enfermedad en el litoral mediterráneo español. Zika virus infection should be suspected in travelers or immigrants with the signs or symptoms of a viral infection (rash, fever, joint pains, conjunctivitis, headache, etc.) and a compatible epidemiological history. Although cutaneous manifestations are among the most common clinical signs of Zika, they are not specific and very few images are available. We present 3 patients (2 travelers and 1 immigrant) in whom a rash was the presenting manifestation of Zika virus infection. Prompt diagnosis optimizes outcomes in these patients, improves the management of severe disease, and minimizes the risk of local transmission by Aedes albopictus, now a potential local vector for the virus due to its presence in areas along Spain's Mediterranean coast.
      Graphical abstract image

      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.02.021
       
  • Ecografía Doppler color en malformaciones glomuvenosas con correlación
           clínica e histológica
    • Authors: X. Wortsman; F. Millard; L. Aranibar
      Abstract: Publication date: Available online 3 July 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): X. Wortsman, F. Millard, L. Aranibar
      Las malformaciones glomuvenosas son hamartomas originados por la presencia de células glómicas en el músculo liso de las estructuras vasculares. Presentamos una serie de 13 casos de malformaciones glomuvenosas evaluadas clínicamente, estudiadas con ecotomografía Doppler color y confirmadas histológicamente. En las ecografías se observaron en todos los casos formaciones dérmicas e hipodérmicas superficiales, moderadamente delimitadas, de ecoestructura mixta, pseudonodulares, hipoecogénicas y heterogéneas con áreas tubulares y lacunares anecogénicas pseudoquísticas. El 85% de los casos demostró presencia de vasos arteriales y venosos, con predominio de los de baja velocidad (≤ 15cm/s) sin shunts arteriovenosos. No se visualizó compromiso de estructuras profundas ni flebolitos. Los hallazgos clínicos y ecográficos podrían ayudar a precisar mejor el diagnóstico, la planificación quirúrgica o el seguimiento no invasivo en estas entidades. Glomuvenous malformations are hamartomatous lesions characterized by the presence of glomus cells in the vascular smooth muscle. We present the clinical and color Doppler ultrasound features of a series of 13 cases of histologically confirmed glomuvenous malformations. In all cases, the ultrasound study revealed moderately delimited superficial dermal and hypodermal pseudonodular structures of mixed echogenicity, with hypoechoic and heterogeneous areas and anechoic, pseudocystic tubular and lacunar zones. Arterial and venous vessels, mainly with a low flow (≤ 15cm/s) were observed in 85% of patients, but no arteriovenous shunts were present. Deeper structures were not affected and no phleboliths were detected. The clinical and ultrasound findings could facilitate diagnosis, surgical planning, and noninvasive follow-up in these tumors.
      Graphical abstract image

      PubDate: 2017-07-04T07:22:11Z
      DOI: 10.1016/j.ad.2017.04.013
       
  • Valor del trasplante capilar realizado por el dermatólogo
    • Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): S. Vañó Galván


      PubDate: 2017-07-04T07:22:11Z
       
  • El eosinófilo como alerta
    • Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): E. Rodríguez Díaz


      PubDate: 2017-07-04T07:22:11Z
       
  • Terapia fotodinámica antimicrobiana: un mundo por explorar
    • Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): J. Romaní


      PubDate: 2017-07-04T07:22:11Z
       
  • Actualización del método Follicular Unit Extraction (FUE) del
           trasplante de pelo
    • Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): F. Jiménez-Acosta, I. Ponce-Rodríguez
      La follicular unit extraction (FUE) es una técnica de trasplante capilar que utiliza punches de pequeño diámetro (0,8-1mm) para extraer las unidades foliculares. Aunque en sus primeros años tuvo escasa aceptación debido a la dificultad en extraer unidades foliculares intactas con un punch tan pequeño, la FUE se ha popularizado y es ya una alternativa a la técnica clásica de la tira (FUT). Entre los motivos, la cada vez mayor demanda por parte de los pacientes y la mayor habilidad de los cirujanos en las extracciones al contar con mejor instrumental y más experiencia. Entre las ventajas de la FUE destaca la reducción de molestias postoperatorias en la zona donante y el aspecto muy poco visible de las cicatrices puntiformes residuales. Sin embargo, la FUE requiere una mayor laboriosidad, aumentando el tiempo operatorio, y una larga curva de aprendizaje por parte del cirujano. Follicular unit extraction (FUE) is a hair transplantation technique that uses small punches (0.8-1 mm in diameter) to extract the follicular units (FUs). Though initially the technique was not widely accepted because of the difficulty of extracting intact follicular units with such small punches, it has since gained in popularity due mainly to rising patient demand, the availability of better instrumentation and greater surgical skill acquired from experience. It is now a recognised alternative to follicular unit transplantation (FUT), a technique based on harvesting the FUs from a strip of tissue. Among the advantages of FUE are less post-procedural discomfort in the donor zone and the barely visible scarring from the punches. However, FUE is a more laborious, time-consuming procedure that involves a long learning curve for the surgeon.

      PubDate: 2017-07-04T07:22:11Z
       
  • Causas y curas de las dermatosis en la obra de Hildegarda de Bingen
    • Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): J. Romaní, M. Romaní


      PubDate: 2017-07-04T07:22:11Z
       
  • Pseudoaneurisma de la arteria temporal superficial
    • Authors: Pigem
      Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): R. Pigem, C. Baliu-Piqué, A. Bennàssar


      PubDate: 2017-07-04T07:22:11Z
       
  • Síndrome de eritema tenar periarticular y onicolisis: una manifestación
           de toxicidad cutánea por taxanos
    • Abstract: Publication date: July–August 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 6
      Author(s): E. Rodríguez-Lomba, I. Molina-López, R. Suárez-Fernández, O. Baniandrés-Rodríguez


      PubDate: 2017-07-04T07:22:11Z
       
 
 
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