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International Journal of Scientific Reports
Number of Followers: 3  Open Access journalISSN (Print) 2454-2156 - ISSN (Online) 2454-2164 This journal is no longer being updated because: the publisher no longer provides RSS feeds |
- The prevalence of premenstrual syndrome symptoms and associated factors
among female medical students at Al-Andalus University: a cross-sectional
study
Authors: Safa K. Salman, Dina I. Esmandar, Enana K. Sarem, Ram F. Attaf
Pages: 95 - 101
Abstract: Background: Premenstrual syndrome (PMS) is a menstrual disorder defined as a cluster of various physical, emotional, and behavioural symptoms that negatively affect women’s quality of life. This cross-sectional study aimed to assess the prevalence of common PMS symptoms and determine their association with body mass index (BMI), lifestyle, dietary habits, perceived stress, menstrual flow, family history and family income among medical students at Al-Andalus University in Syria. Methods: A sample of 205 female students were interviewed and filled out a questionnaire. All data were coded and entered into excel (Microsoft 2019). One-way analysis of variance (ANOVA) and Chi-square tests were used to evaluate the association between PMS symptoms and the studied factors. Results: The most frequently reported PMS symptoms were anxiety (80%), bloating (74.6%), and breast tenderness (62.9%). Our study found a significant association between weight gain pre-menstruation and BMI (p=0.02). A significant relationship was found between increased premenstrual consumption of sweets and both breast tenderness and bloating (p=0.01). Daily consumption of coffee was significantly correlated with weight gain and headaches (p<0.001). This study found a significant relationship between smoking cigarettes and abdominal and back pain (p=0.04, p=0.02, respectively). Smoking shisha was significantly associated with fatigue and bloating (p=0.01, p<0.001, respectively). A significant relationship was found between menstrual flow and both abdominal pain and headaches (p=0.01, p=0.02, respectively). Conclusions: A high prevalence of PMS symptoms was reported in Al-Andalus University female medical students. Additionally, this study found multiple significant associations between BMI, dietary habits, lifestyle, menstrual flow and the severity of symptoms.
PubDate: 2024-03-28
DOI: 10.18203/issn.2454-2156.IntJSciRep20240713
Issue No: Vol. 10, No. 4 (2024)
- Estimation of thermodynamics properties as a measure of the extent of
interference in a conducting polymer based electrochemical aqueous ion
sensor
Authors: Kusumita Dutta, Siddhartha Panda
Pages: 102 - 110
Abstract: Background: Interference of other ions towards the target analyte in an electrochemical sensor is typically estimated utilizing the peak reduction (PR) technique and the selectivity coefficient technique, both of which have limitations. In our earlier works, a scale of interference was developed using the barrier width (BW) technique based on Simmon’s model utilizing a conducting polymer-based sensor for the detection of Cd2+ by square wave voltammetry (SWV). Also, a new scale of interference was generated with higher resolution by incorporating the BW technique along with adsorption isotherms and the PR technique. Methods: The present work takes the investigation further at the electrode-electrolyte interface to explain the interference effect using thermodynamic parameters such as the partition coefficient, enthalpy and reorganization energy. The length of the reaction site for Cd2+ can also measure interference effect. In this work, SWV for Cd2+ detection in presence of interfering species at different temperatures were conducted, -ΔGad values were extracted and all the thermodynamic parameters were evaluated. The novelty of this work lies in incorporation of these thermodynamic parameters along with BW values (d) to explain the interference phenomena. Results: The variation of the thermodynamic properties for Cd2+ in presence of interfering species were examined. Correlation coefficients were developed from the thermodynamic parameters and the d values to explain the extent of interference. Conclusions: This study can provide information on the thermodynamic properties which can be predicted from BW technique. The correlation coefficients would help obtain an estimate of the interference with the need of lesser number of experiments.
PubDate: 2024-03-19
DOI: 10.18203/issn.2454-2156.IntJSciRep20240688
Issue No: Vol. 10, No. 4 (2024)
- An analysis of indices and ratios in anthropometric body measurements
among team sports athletes
Authors: Md. Hamidur Rahman, J. P. Sharma
Pages: 111 - 119
Abstract: Background: Physical indices and proportions based on anthropometry are crucial for determining the performance of players in team sports. The study aims to analyze the anthropometric status, body mass and shape indices, including waist-to-hip and height ratios, among athletes from different team sports. Methods: Study involved 135 male team-sport athletes specializing in basketball, handball, and volleyball, with 45 players in each sport. Researchers collected anthropometric data, including chronological age (CA), height (Ht), weight (Wt), body mass index (BMI), waist circumferences (WC) and hip circumferences (HC), waist-hip ratio (WHR), waist-height ratio (WHtR), and a body shape index (ABSI). To compare variables across groups, descriptive statistics and one-way ANOVA with LSD post-hoc tests used. Relationships within each group were examined using correlation analysis. Results: The ANOVA findings indicated F-values (2, 132) for CA at 0.57, p=0.57, BMI at 0.59, p=0.56, WC at 2.10, p=0.13, WHR at 1.37, p=0.27, and ABSI at 1.41, p=0.25, respectively, revealing no significant disparities among the groups. Conversely, Ht at 13.36, p=0.00, Wt at 5.74, p=0.00, HC at 6.33, p=0.00, and WHtR at 3.60, p=0.03, respectively, highlighted significant variations between the groups. Furthermore, the correlation of BMI, WC, HC, WHR, WHtR, and ABSI in each group showed a strong positive correlation (p<0.01). Conclusions: Athletes in team sports were found to have similar body mass and shape indices, including ratios for WHR, while the WHtR ratio showed significant variations among the groups. Despite these differences, measures of athletes’ health metrics across these sports remain within safe, normal ranges.
PubDate: 2024-03-28
DOI: 10.18203/issn.2454-2156.IntJSciRep20240714
Issue No: Vol. 10, No. 4 (2024)
- A meta-analysis evaluating the role of calcium channel alpha-2 delta-1
subunit in carcinogenesis
Authors: Chandan Raybarman, Surajit Bhattacharjee
Pages: 120 - 129
Abstract: There is hardly found any study accumulating all the experiments reported with the expression of alpha-2 delta-1 (α2δ-1) in cancer cells. This meta-analysis aimed to advance our knowledge about the role of calcium channel alpha2 delta-1 subunit in carcinogenesis in the present time. PubMed searches for peer-reviewed articles were conducted using the keywords “α2δ-1 protein in oncogenesis”, “α2δ-1 protein expression in cancer cells”, and “α2δ-1 protein as cancer cell marker”. The databases were developed in accordance with PRISMA guidelines. Seventeen studies out of 80 citations met the inclusion criteria pertaining to α2δ-1 expression in different cancer cells. The cancer patterns were hepatocellular carcinoma in 41%, non-small cell lung carcinoma in 12% and laryngeal squamous cell carcinoma in 12%. The remaining studies included small-cell lung cancer (6%), gastric cancer (6%), pancreatic cancer (6%), hypopharyngeal squamous cell carcinoma (6%), breast cancer (6%) and glioblastoma multiforme (6%). α2δ-1+ cells had a higher sphere-forming and tumorigenic efficiency in 76.5% of experiments. 58.8% experiments explored mechanistically in self-renewal efficiency and tumorigenesis of α2δ-1+ cancer cells. The cancer cells expressing α2δ-1 have the potential to serve as cell surface markers for tumour-initiating cells and cancer stem cells. These intriguing findings open up a promising avenue for future research, focusing on the targeting of α2δ-1 as a potential therapeutic strategy for cancer treatment.
PubDate: 2024-03-28
DOI: 10.18203/issn.2454-2156.IntJSciRep20240715
Issue No: Vol. 10, No. 4 (2024)
- Need of rural communities to be engaged and empowered for global health
and wellness
Authors: S. Chhabra
Pages: 130 - 134
Abstract: For health and wellness rural communities do many things with whatever they have, use various modalities of actions for prevention, therapy of disorders, maintenance, promotion of health. Also, for everyday life they do various activities which affect their health. Present article is based on observations, information in context of activities by rural people for their health and wellness. Personal observations, experiences were added to information about actions by rural communities for health and wellness. Rural communities use their own wisdom, do many things with whatever they have for living a healthy life. They use various modalities during pregnancy, birth for mother, new born, persons of all ages. Therapies are used for pregnancy care, birth, post birth, other illnesses, injuries and so on. In modern day practice it has become essential to priorities modes of actions for best therapy, best outcome without harmful effects. In addition to various actions for prevention, therapy, maintenance and promotion of health and wellness, communities do other activities which impact their health. This needs sharing for best of global health. Communities use many modalities for therapy, prevention of disorders, rehabilitation and health promotion. Need is of learning from them, adding science to such modes if needed, robust evaluation of community actions with long term outcomes, cost-effectiveness, in various settings globally. World needs to know and use for healthy life and make communities aware of modern medicine, technology wherever essential for global health.
PubDate: 2024-03-28
DOI: 10.18203/issn.2454-2156.IntJSciRep20240716
Issue No: Vol. 10, No. 4 (2024)
- Atypical electroclinical presentation of Landau Kleffner syndrome: a case
report of an 8 year old Nigerian child
Authors: Chuks G. Nwala, Omokhuale M. Ejemierele
Pages: 135 - 138
Abstract: Epileptic seizures account for common neurologic presentations in paediatric neurology units in developing countries. Atypical presentation of syndromic epilepsy may be missed especially sensory, psychic or autonomic manifestations. An 8 year old male Nigerian child presented with recurrent vomiting and delayed motor milestones, regression of speech (acquired aphasia) with unremarkable birth history or any underlying medical or surgical condition. He had delayed gross motor development and continuous bilateral polyspike waves of slow sleep on EEG. Self-limited autonomic epileptic seizure syndrome which was a strong differential of autonomic seizures in early childhood was not suggestive as his EEG findings failed to demonstrate occipital spike wave pattern nor did photic stimulation evoke any epileptiform waves. Child made significant clinical improvement with anticonvulsants, neuro vitamins, and behavioural therapy, evidenced by regain of non-verbal communication, resolution of autonomic symptoms and temper tantrums. A high index of suspicion should be applied in patients with acquired aphasia with subclinical or recurrent autonomic symptoms.
PubDate: 2024-03-28
DOI: 10.18203/issn.2454-2156.IntJSciRep20240717
Issue No: Vol. 10, No. 4 (2024)
- Trofinetide providing a promising avenue for the treatment of Rett
syndrome
Authors: Raja Devendar, Anum Fatima Shigri, Maheera Khan
Pages: 139 - 140
Abstract: Rett syndrome (RTT) is a developmental disability associated primarily with the abnormal functioning of the nervous system. Affecting 1 in 10,000-15,000 women, it results from an inactivating modification in the X-linked genetic code, methyl-CpG-binding protein 2 (MECP2), which codes for a protein that binds to DNA and regulates transcription. Girls with RTT are born with normal prenatal and perinatal periods and appear to be in good health. Their psychomotor growth is typical up to their first or second year of life, at which point brain functional regression starts. Clinical signs of the regression include the emergence of stereotyped hand movements, a loss of fine motor skills, gait apraxia, verbal and nonverbal communication deficits, and epileptic seizures.
PubDate: 2024-03-28
DOI: 10.18203/issn.2454-2156.IntJSciRep20240718
Issue No: Vol. 10, No. 4 (2024)
