Publisher: Medip Academy   (Total: 12 journals)   [Sort by number of followers]

Showing 1 - 12 of 12 Journals sorted alphabetically
Intl. J. of Advances in Medicine     Open Access   (Followers: 1)
Intl. J. of Basic & Clinical Pharmacology     Open Access   (Followers: 1)
Intl. J. of Clinical Trials     Open Access   (Followers: 3)
Intl. J. of Community Medicine and Public Health     Open Access   (Followers: 4)
Intl. J. of Contemporary Pediatrics     Open Access   (Followers: 2)
Intl. J. of Otorhinolaryngology and Head and Neck Surgery     Open Access  
Intl. J. of Reproduction, Contraception, Obstetrics and Gynecology     Open Access   (Followers: 9)
Intl. J. of Research in Dermatology     Open Access   (Followers: 1)
Intl. J. of Research in Medical Sciences     Open Access   (Followers: 4)
Intl. J. of Research in Orthopaedics     Open Access   (Followers: 1)
Intl. J. of Scientific Reports     Open Access   (Followers: 3)
Intl. Surgery J.     Open Access   (Followers: 2)
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International Journal of Scientific Reports
Number of Followers: 3  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2454-2156 - ISSN (Online) 2454-2164
Published by Medip Academy Homepage  [12 journals]
  • Effect of two different doses of oral midazolam premedication on
           separation anxiety in children scheduled for herniotomy

    • Authors: Samuel B. Olamuyiwa, Alfred T. Aggo, Uyoata U. Johnson
      Pages: 28 - 34
      Abstract: Background: Peri-operative separation anxiety in children adversely impacts on their cognitive function and behavioural outcome. The aim of the study was to assess the effect of two different doses of oral midazolam premedication on separation anxiety in paediatric patients scheduled for herniotomy. Methods: Eighty-four eligible children aged 1-6 years, of American Society of Anesthesiologists (ASA) class I or II, scheduled for herniotomy, were randomized into two groups, A and B, of 42 each after ethical clearance and written parental consent. Children in group A and group B received 0.5 mg/kg and 0.75 mg/kg respectively of oral midazolam flavoured with paracetamol syrup, were observed, and later separated from parents at 30 min post-premedication. Premedicant acceptability was noted, and separation anxiety was assessed using the Richmond agitation sedation scale (RASS). Statistical significance was set at p<0.05. Results: All 84 children completed the study. At 30 min post-premedication, 47.6% in group A and 19.1% in group B had light sedation, while 52.4% in group A and 80.9% in group B were moderately sedated, p=0.0001. Premedicant acceptability and agitation scores between the groups were comparable, p>0.05. Conclusions: Oral 0.5 mg/kg and 0.75 mg/kg midazolam induced desirable sedation in children at the 30th min with comparable lower agitation scores; however, the 0.75 mg/kg dose achieved significantly faster onset and higher level of sedation in a greater proportion of the subjects.
      PubDate: 2023-01-24
      DOI: 10.18203/issn.2454-2156.IntJSciRep20230111
      Issue No: Vol. 9, No. 2 (2023)
       
  • Knowledge, attitude and practices related to drug prescription among
           medical officers and postgraduate residents in B. P. Koirala Institute of
           Health Sciences

    • Authors: Dillisher Rai, Gajendra P. Rauniar, Dipesh R. Pandey, Namita K. Mandal, Deependra P. Sarraf
      Pages: 35 - 40
      Abstract: Background: Pharmacology, being both basic and applied science, forms the backbone of rational therapeutics. Traditional teaching of pharmacology is teacher centered with emphasis on learning the facts on drugs. Inadequate knowledge may cause irrational prescribing which leads to huge loss of lives and money. Objective was to evaluate the knowledge, attitude and practices among doctors regarding prescription. Methods: A semi-structured questionnaire was used among medical officers and postgraduate residents to collect the data regarding their undergraduate training in clinical pharmacology and therapeutics, prescribing habits, commonly consulted drug information sources and any perceived deficiencies in their undergraduate clinical pharmacology teaching. Descriptive statistics were calculated. Results: Out of 116 respondents, 69 were males and mean age was 28.8±2.3 years. Ninety-eight (84.5%) participants were aware about teaching of prescription writing in their undergraduate course and 101 (87.1%) participants knew the parts of prescription. One hundred (86.2%) participants considered safety as the most important aspects of prescribing a drug. One hundred and four (89.7%) participants thought that undergraduate pharmacology training taught them to prescribe safely. One hundred and eleven (95.7%) thought that the undergraduate pharmacology teaching should be improved. Out of 116 participants, 84 (72.4%) had encountered problems while prescribing during their internship. Sixty-eight (58.6%) participants used internet as a source of information about safety, efficacy and cost of drugs for prescription. Ninety-five (81.9%) participants prescribed supplemental vitamins and irons according to patient need. Conclusions: Majority of participants felt that they do have good knowledge in prescribing medicines and the training on prescription writing should be reinforced.
      PubDate: 2023-01-20
      DOI: 10.18203/issn.2454-2156.IntJSciRep20230044
      Issue No: Vol. 9, No. 2 (2023)
       
  • Intra-operative cardiac arrest from undiagnosed incretic placenta praevia
           precipitated haemorrhage reversed via external jugular access: a case
           report

    • Authors: Alfred Tamunoigbanibo Aggo, Samuel Bobola Olamuyiwa
      Pages: 41 - 44
      Abstract: A 32-year old obese multipara with undiagnosed incretic major degree placenta praevia was scheduled to have an elective repeat Caesarean for two previous caesarean. Under subarachnoid anaesthesia, placental severance and myometrial avulsion precipitated torrential haemorrhage occasioning intraoperative cardiac arrest which necessitated external jugular access for successful resuscitation. Following peripartum hysterectomy under general anaesthesia, she received intensive care and was discharged to the ward after 48 hours. This report highlights the necessity of accurate prenatal diagnosis of invasive placentation and the grave sequelae of a missed diagnosis, as well as the strategic significance of external jugular access in resuscitation post-cardiac arrest from massive haemorrhage.
      PubDate: 2023-01-24
      DOI: 10.18203/issn.2454-2156.IntJSciRep20230112
      Issue No: Vol. 9, No. 2 (2023)
       
  • The role and behaviour of mitochondrial creatine kinase in hepatocellular
           carcinoma and its potential use as a tumor detecting biomarker for cancer
           patients

    • Authors: Ali Nemati Siyahmazgi, Mina Ghorbani Mazar, Maede Vakilinia, Hossein Javid
      Pages: 45 - 55
      Abstract: Hepatocellular carcinoma (HCC) is responsible for approximately 75% of all liver cancer cases, which is the seventh most prevalent cancer and the second most common cause of cancer mortality worldwide. The prognosis of HCC depends on its stage and the severity of liver disease at the time of diagnosis, but there are still problems in detecting and treating HCC patients on time and effectively. Being unable to diagnose HCC patients at an early stage and ineffective therapies for HCC patients with advanced stages are associated with the disease's high mortality. Liver transplantation could be a treatment option If patients are diagnosed early, but unfortunately, most patients are diagnosed at an advanced stage where chemotherapy is necessary. Thus, an effective strategy for early detection of HCC is necessary since there was no effective chemotherapy for advanced HCC for a long time, and therapies such as the anti-angiogenesis pathway can only extend the median survival from 7.9 months to 10.7 months which is a step forward but not enough. In this article, we review the role of MtCK in HCC and its potential use as a marker to see if using it can be beneficial to patients.
      PubDate: 2023-01-24
      DOI: 10.18203/issn.2454-2156.IntJSciRep20230113
      Issue No: Vol. 9, No. 2 (2023)
       
 
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