Publisher: ACS   (Total: 68 journals)   [Sort alphabetically]

Showing 1 - 68 of 68 Journals sorted by number of followers
Biochemistry     Hybrid Journal   (Followers: 484, SJR: 1.685, CiteScore: 3)
J. of the American Chemical Society     Hybrid Journal   (Followers: 465, SJR: 8.127, CiteScore: 14)
ACS Chemical Biology     Hybrid Journal   (Followers: 451, SJR: 2.57, CiteScore: 5)
ACS Nano     Hybrid Journal   (Followers: 448, SJR: 7.203, CiteScore: 14)
Analytical Chemistry     Hybrid Journal   (Followers: 351, SJR: 2.362, CiteScore: 6)
Environmental Science & Technology     Hybrid Journal   (Followers: 347, SJR: 2.535, CiteScore: 7)
Chemistry of Materials     Hybrid Journal   (Followers: 336, SJR: 4.675, CiteScore: 10)
Chemical Reviews     Hybrid Journal   (Followers: 265, SJR: 23.414, CiteScore: 51)
The J. of Organic Chemistry     Hybrid Journal   (Followers: 247, SJR: 1.846, CiteScore: 5)
J. of Medicinal Chemistry     Hybrid Journal   (Followers: 223, SJR: 2.567, CiteScore: 6)
Accounts of Chemical Research     Hybrid Journal   (Followers: 222, SJR: 11.139, CiteScore: 21)
Organic Letters     Hybrid Journal   (Followers: 210, SJR: 2.853, CiteScore: 6)
Nano Letters     Hybrid Journal   (Followers: 76, SJR: 7.447, CiteScore: 13)
ACS Catalysis     Hybrid Journal   (Followers: 76, SJR: 4.921, CiteScore: 11)
Langmuir     Hybrid Journal   (Followers: 66, SJR: 1.479, CiteScore: 4)
Macromolecules     Hybrid Journal   (Followers: 56, SJR: 2.419, CiteScore: 6)
J. of Physical Chemistry B     Hybrid Journal   (Followers: 51, SJR: 1.331, CiteScore: 3)
ACS Medicinal Chemistry Letters     Hybrid Journal   (Followers: 49, SJR: 1.388, CiteScore: 3)
J. of Physical Chemistry C     Hybrid Journal   (Followers: 45, SJR: 2.135, CiteScore: 5)
ACS Applied Materials & Interfaces     Hybrid Journal   (Followers: 44, SJR: 2.784, CiteScore: 8)
Organic Process Research & Development     Hybrid Journal   (Followers: 43, SJR: 1.405, CiteScore: 3)
ACS Synthetic Biology     Hybrid Journal   (Followers: 40, SJR: 2.625, CiteScore: 5)
Inorganic Chemistry     Hybrid Journal   (Followers: 39, SJR: 1.892, CiteScore: 5)
Energy & Fuels     Hybrid Journal   (Followers: 37, SJR: 1.159, CiteScore: 4)
J. of Physical Chemistry A     Hybrid Journal   (Followers: 37, SJR: 1.17, CiteScore: 3)
J. of Physical Chemistry Letters     Hybrid Journal   (Followers: 35, SJR: 4.667, CiteScore: 8)
ACS Macro Letters     Hybrid Journal   (Followers: 34, SJR: 2.486, CiteScore: 6)
Bioconjugate Chemistry     Hybrid Journal   (Followers: 28, SJR: 1.801, CiteScore: 4)
J. of Chemical Education     Hybrid Journal   (Followers: 28, SJR: 0.466, CiteScore: 2)
Biomacromolecules     Hybrid Journal   (Followers: 27, SJR: 1.95, CiteScore: 6)
Chemical Research in Toxicology     Hybrid Journal   (Followers: 25, SJR: 1.187, CiteScore: 4)
ACS Chemical Neuroscience     Hybrid Journal   (Followers: 25, SJR: 1.442, CiteScore: 4)
ACS Combinatorial Science     Hybrid Journal   (Followers: 25, SJR: 1.049, CiteScore: 3)
Chemical and Engineering News     Free   (Followers: 25, SJR: 0.145, CiteScore: 0)
Industrial & Engineering Chemistry Research     Hybrid Journal   (Followers: 24, SJR: 0.978, CiteScore: 3)
Organometallics     Hybrid Journal   (Followers: 22, SJR: 1.652, CiteScore: 4)
J. of Natural Products     Hybrid Journal   (Followers: 21, SJR: 1.368, CiteScore: 4)
Molecular Pharmaceutics     Hybrid Journal   (Followers: 20, SJR: 1.572, CiteScore: 5)
J. of Chemical Information and Modeling     Hybrid Journal   (Followers: 20, SJR: 1.349, CiteScore: 4)
Crystal Growth & Design     Hybrid Journal   (Followers: 19, SJR: 1.154, CiteScore: 4)
J. of Chemical Theory and Computation     Hybrid Journal   (Followers: 19, SJR: 2.497, CiteScore: 5)
ACS Photonics     Hybrid Journal   (Followers: 19, SJR: 3.376, CiteScore: 7)
J. of Agricultural and Food Chemistry     Hybrid Journal   (Followers: 14, SJR: 1.269, CiteScore: 4)
J. of Proteome Research     Hybrid Journal   (Followers: 14, SJR: 1.818, CiteScore: 4)
ACS Central Science     Open Access   (Followers: 14, SJR: 5.022, CiteScore: 7)
ACS Biomaterials Science and Engineering     Hybrid Journal   (Followers: 14)
ACS Applied Polymer Materials     Hybrid Journal   (Followers: 14)
Industrial & Engineering Chemistry     Full-text available via subscription   (Followers: 11)
J. of Chemical & Engineering Data     Hybrid Journal   (Followers: 11, SJR: 0.925, CiteScore: 2)
ACS ES&T Engineering     Hybrid Journal   (Followers: 9)
ACS Applied Nano Materials     Hybrid Journal   (Followers: 9)
ACS Energy Letters     Hybrid Journal   (Followers: 9)
ACS Sustainable Chemistry & Engineering     Hybrid Journal   (Followers: 9, SJR: 1.657, CiteScore: 6)
ACS Earth and Space Chemistry     Free   (Followers: 8)
Environmental Science & Technology Letters     Hybrid Journal   (Followers: 7)
ACS infectious diseases     Hybrid Journal   (Followers: 7, SJR: 1.618, CiteScore: 4)
ACS Pharmacology & Translational Science     Hybrid Journal   (Followers: 6)
Advances in Chemistry     Full-text available via subscription   (Followers: 6)
ACS ES&T Water     Hybrid Journal   (Followers: 5)
Applied Energy Materials     Hybrid Journal   (Followers: 5)
ACS Omega     Open Access   (Followers: 5)
ACS Chemical Health & Safety     Hybrid Journal   (Followers: 5, SJR: 0.207, CiteScore: 0)
ACS Sensors     Hybrid Journal   (Followers: 4)
Rubber Chemistry and Technology     Full-text available via subscription   (Followers: 3, SJR: 0.315, CiteScore: 1)
ACS Materials Letters     Open Access   (Followers: 3)
Accounts of Materials Research     Hybrid Journal  
JACS Au     Open Access  
C&EN Global Enterprise     Full-text available via subscription  
Similar Journals
Journal Cover
Journal of Medicinal Chemistry
Journal Prestige (SJR): 2.567
Citation Impact (citeScore): 6
Number of Followers: 223  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0022-2623 - ISSN (Online) 1520-4804
Published by ACS Homepage  [68 journals]
  • Enterococcus+faecalis&rft.title=Journal+of+Medicinal+Chemistry&rft.issn=0022-2623&rft.date=2021&rft.volume=&rft.aulast=Chen&rft.aufirst=Zhong&rft.au=Zhong+Chen&rft.au=Kun+Song,++Yongpeng+Shang,++Yanpeng+Xiong,++Zhihui+Lyu,++Junwen+Chen,++Jinxin+Zheng,++Peiyu+Li,++Yang+Wu,++Chenjian+Gu,++Youhua+Xie,++Qiwen+Deng,++Zhijian+Yu,++Jian+Zhang,++Di+Qu">[ASAP] Selection and Identification of Novel Antibacterial Agents against
           Planktonic Growth and Biofilm Formation of Enterococcus faecalis

    • Free pre-print version: Loading...

      Authors: Zhong Chen; Kun Song, Yongpeng Shang, Yanpeng Xiong, Zhihui Lyu, Junwen Chen, Jinxin Zheng, Peiyu Li, Yang Wu, Chenjian Gu, Youhua Xie, Qiwen Deng, Zhijian Yu, Jian Zhang, Di Qu
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00939
      PubDate: Sat, 16 Oct 2021 04:00:00 GMT
       
  • In+Vivo&rft.title=Journal+of+Medicinal+Chemistry&rft.issn=0022-2623&rft.date=2021&rft.volume=&rft.aulast=Jones&rft.aufirst=J.&rft.au=J.+Howard+Jones&rft.au=Zhili+Xin,++Martin+Himmelbauer,++Michael+Dechantsreiter,++Istvan+Enyedy,++Joseph+Hedde,++Terry+Fang,++Janaky+Coomaraswamy,++Kristopher+W.+King,++Paramasivam+Murugan,++Joseph+C.+Santoro,++Thomas+Hesson,++Dirk+M.+Walther,++Ru+Wei,++Fengmei+Zheng,++Douglas+J.+Marcotte,++Kerri+Spilker,++P.+Rajesh+Kumar,++Ying+Liu,++Rab+Gilfillan,++Felix+Gonzalez-Lopez+de+Turiso">[ASAP] Discovery of Potent, Selective, and Brain-Penetrant Apoptosis
           Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain
           Inflammation In Vivo

    • Free pre-print version: Loading...

      Authors: J. Howard Jones; Zhili Xin, Martin Himmelbauer, Michael Dechantsreiter, Istvan Enyedy, Joseph Hedde, Terry Fang, Janaky Coomaraswamy, Kristopher W. King, Paramasivam Murugan, Joseph C. Santoro, Thomas Hesson, Dirk M. Walther, Ru Wei, Fengmei Zheng, Douglas J. Marcotte, Kerri Spilker, P. Rajesh Kumar, Ying Liu, Rab Gilfillan, Felix Gonzalez-Lopez de Turiso
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01458
      PubDate: Fri, 15 Oct 2021 04:00:00 GMT
       
  • [ASAP] Development of BromoTag: A “Bump-and-Hole”–PROTAC System to
           

    • Free pre-print version: Loading...

      Authors: Adam G. Bond; Conner Craigon, Kwok-Ho Chan, Andrea Testa, Athanasios Karapetsas, Rotimi Fasimoye, Thomas Macartney, J. Julian Blow, Dario R. Alessi, Alessio Ciulli
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01532
      PubDate: Fri, 15 Oct 2021 04:00:00 GMT
       
  • [ASAP] Visualization of Receptor-Interacting Protein Kinase 1 (RIPK1) by
           Brain Imaging with Positron Emission Tomography

    • Free pre-print version: Loading...

      Authors: Yu Lan; Ping Bai, Yan Liu, Sepideh Afshar, Robin Striar, Anna Kathryn Rattray, Tyler Nicholas Meyer, Amelia G. Langan, Alisa M. Posner, Shiqian Shen, Rudolph E. Tanzi, Can Zhang, Changning Wang
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01477
      PubDate: Fri, 15 Oct 2021 04:00:00 GMT
       
  • [ASAP] Discovery of a Highly Potent and Selective Degrader Targeting
           Hematopoietic Prostaglandin D Synthase via In Silico Design

    • Free pre-print version: Loading...

      Authors: Hidetomo Yokoo; Norihito Shibata, Akinori Endo, Takahito Ito, Yuta Yanase, Yuki Murakami, Kiyonaga Fujii, Kengo Hamamura, Yasushi Saeki, Mikihiko Naito, Kosuke Aritake, Yosuke Demizu
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01206
      PubDate: Fri, 15 Oct 2021 04:00:00 GMT
       
  • [ASAP] Discovery of Umibecestat (CNP520): A Potent, Selective, and
           Efficacious β-Secretase (BACE1) Inhibitor for the Prevention of
           Alzheimer’s Disease

    • Free pre-print version: Loading...

      Authors: Rainer Machauer; Rainer Lueoend, Konstanze Hurth, Siem J. Veenstra, Heinrich Rueeger, Markus Voegtle, Marina Tintelnot-Blomley, Jean-Michel Rondeau, Laura H. Jacobson, Grit Laue, Karen Beltz, Ulf Neumann
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01300
      PubDate: Thu, 14 Oct 2021 04:00:00 GMT
       
  • [ASAP] Synthesis and Structural Characterization of Ricin Inhibitors
           Targeting Ribosome Binding Using Fragment-Based Methods and
           Structure-Based Design

    • Free pre-print version: Loading...

      Authors: Xiao-Ping Li; Rajesh K. Harijan, Bin Cao, Jennifer N. Kahn, Michael Pierce, Anastasiia M. Tsymbal, Jacques Y. Roberge, David Augeri, Nilgun E. Tumer
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01370
      PubDate: Thu, 14 Oct 2021 04:00:00 GMT
       
  • [ASAP] Discovery of a Series of Hydroxamic Acid-Based Microtubule
           Destabilizing Agents with Potent Antitumor Activity

    • Free pre-print version: Loading...

      Authors: Linyu Yang; Wanhua Zhang, Qiang Qiu, Zhengying Su, Minghai Tang, Peng Bai, Wenting Si, Zejiang Zhu, Yan Liu, Jianhong Yang, Shuang Kuang, Jiang Liu, Wei Yan, Mingsong Shi, Haoyu Ye, Zhuang Yang, Lijuan Chen
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01451
      PubDate: Thu, 14 Oct 2021 04:00:00 GMT
       
  • [ASAP] Development of the First Aliphatic 18F-Labeled Tetrazine Suitable
           for Pretargeted PET Imaging—Expanding the Bio-orthogonal Tool Box

    • Free pre-print version: Loading...

      Authors: Umberto M. Battisti; Klas Bratteby, Jesper T. Jrgensen, Lars Hvass, Vladimir Shalgunov, Hannes Mikula, Andreas Kjær, Matthias Manfred Herth
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01326
      PubDate: Thu, 14 Oct 2021 04:00:00 GMT
       
  • [ASAP] Reactivities of the Front Pocket N-Terminal Cap Cysteines in Human
           Kinases

    • Free pre-print version: Loading...

      Authors: Ruibin Liu; Shaoqi Zhan, Ye Che, Jana Shen
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01186
      PubDate: Thu, 14 Oct 2021 04:00:00 GMT
       
  • [ASAP] Structure–Activity Relationship of USP5 Inhibitors

    • Free pre-print version: Loading...

      Authors: Mandeep K. Mann; Carlos A. Zepeda-Velázquez, Héctor González-Álvarez, Aiping Dong, Taira Kiyota, Ahmed M. Aman, Peter Loppnau, Yanjun Li, Brian Wilson, Cheryl H. Arrowsmith, Rima Al-Awar, Rachel J. Harding, Matthieu Schapira
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00889
      PubDate: Thu, 14 Oct 2021 04:00:00 GMT
       
  • [ASAP] Design of Transmembrane Mimetic Structural Probes to Trap Different
           Stages of γ-Secretase–Substrate Interaction

    • Free pre-print version: Loading...

      Authors: Sanjay Bhattarai; Sujan Devkota, Michael S. Wolfe
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01395
      PubDate: Thu, 14 Oct 2021 04:00:00 GMT
       
  • [ASAP] Discovery of a Series of 7-Azaindoles as Potent and Highly
           Selective CDK9 Inhibitors for Transient Target Engagement

    • Free pre-print version: Loading...

      Authors: Bernard Barlaam; Chris De Savi, Allan Dishington, Lisa Drew, Andrew D. Ferguson, Douglas Ferguson, Chungang Gu, Sudhir Hande, Lorraine Hassall, Janet Hawkins, Alexander W. Hird, Jane Holmes, Michelle L. Lamb, Andrew S. Lister, Thomas M. McGuire, Jane E. Moore, Nichole O’Connell, Anil Patel, Kurt G. Pike, Ujjal Sarkar, Wenlin Shao, Darren Stead, Jeffrey G. Varnes, Melissa M. Vasbinder⋈, Lei Wang, Liangwei Wu, Lin Xue, Bin Yang, Tieguang Yao
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01249
      PubDate: Thu, 14 Oct 2021 04:00:00 GMT
       
  • [ASAP] Discovery of 2-(Ortho-Substituted Benzyl)-Indole Derivatives as
           Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity

    • Free pre-print version: Loading...

      Authors: Biao Lu; Dong Liu, Bin Gui, Jun Gou, Huaide Dong, Qiyue Hu, Jun Feng, Yuchang Mao, Xiaodong Shen, Shenglan Wang, Caihua Zhang, Ru Shen, Yinfa Yan, Lei Chen, Huiyun Wang, Di Li, Jiayin Zhang, Minsheng Zhang, Rumin Zhang, Chang Bai, Feng He, Weikang Tao, Suxing Liu
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00828
      PubDate: Wed, 13 Oct 2021 04:00:00 GMT
       
  • [ASAP] Design, Synthesis, and Biological Evaluation of Icaritin
           Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma
           Treatment

    • Free pre-print version: Loading...

      Authors: Yi Hou; Wenbin Kuang, Wenjian Min, Ziwen Liu, Fang Zhang, Kai Yuan, Xiao Wang, Chengliang Sun, Hao Cheng, Liping Wang, Yibei Xiao, Sheban Pu, Gui-Zhong Xin, Peng Yang
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00087
      PubDate: Wed, 13 Oct 2021 04:00:00 GMT
       
  • S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one+(IACS-15414),+a+Potent+and+Orally+Bioavailable+SHP2+Inhibitor&rft.title=Journal+of+Medicinal+Chemistry&rft.issn=0022-2623&rft.date=2021&rft.volume=&rft.aulast=Czako&rft.aufirst=Barbara&rft.au=Barbara+Czako&rft.au=Yuting+Sun,++Timothy+McAfoos,++Jason+B.+Cross,++Paul+G.+Leonard,++Jason+P.+Burke,++Christopher+L.+Carroll,++Ningping+Feng,++Angela+L.+Harris,++Yongying+Jiang,++Zhijun+Kang,++Jeffrey+J.+Kovacs,++Pijus+Mandal,++Brooke+A.+Meyers,++Faika+Mseeh,++Connor+A.+Parker,++Simon+S.+Yu,++Christopher+C.+Williams,++Qi+Wu,++Maria+Emilia+Di+Francesco,++Giulio+Draetta,++Timothy+Heffernan,++Joseph.+R.+Marszalek,++Nancy+E.+Kohl,++Philip+Jones">[ASAP] Discovery of
           6-[(3S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one
           (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor

    • Free pre-print version: Loading...

      Authors: Barbara Czako; Yuting Sun, Timothy McAfoos, Jason B. Cross, Paul G. Leonard, Jason P. Burke, Christopher L. Carroll, Ningping Feng, Angela L. Harris, Yongying Jiang, Zhijun Kang, Jeffrey J. Kovacs, Pijus Mandal, Brooke A. Meyers, Faika Mseeh, Connor A. Parker, Simon S. Yu, Christopher C. Williams, Qi Wu, Maria Emilia Di Francesco, Giulio Draetta, Timothy Heffernan, Joseph. R. Marszalek, Nancy E. Kohl, Philip Jones
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01132
      PubDate: Wed, 13 Oct 2021 04:00:00 GMT
       
  • [ASAP] Discovery of Reldesemtiv, a Fast Skeletal Muscle Troponin Activator
           for the Treatment of Impaired Muscle Function

    • Free pre-print version: Loading...

      Authors: Scott E. Collibee; Gustave Bergnes, Chihyuan Chuang, Luke Ashcraft, Jeffrey Gardina, Marc Garard, Chris R. Jamison, Kevin Lu, Pu-Ping Lu, Alexander Muci, Antonio Romero, Ellen Valkevich□, Wenyue Wang, Jeffrey Warrington, Bing Yao, Nickie Durham, James Hartman, Anna Marquez, Aaron Hinken, Julia Schaletzky, Donghong Xu, Darren T. Hwee, David Morgans, Fady I. Malik, Bradley P. Morgan
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01067
      PubDate: Tue, 12 Oct 2021 04:00:00 GMT
       
  • [ASAP] Structure Activity Relationships for a Series of Eticlopride-Based
           Dopamine D2/D3 Receptor Bitopic Ligands

    • Free pre-print version: Loading...

      Authors: Anver Basha Shaik; Comfort A. Boateng, Francisco O. Battiti, Alessandro Bonifazi, Jianjing Cao, Li Chen, Rezvan Chitsazi, Saiprasad Ravi, Kuo Hao Lee, Lei Shi, Amy Hauck Newman
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01353
      PubDate: Tue, 12 Oct 2021 04:00:00 GMT
       
  • [ASAP] Development and Profiling of Inverse Agonist Tools for the
           Neuroprotective Transcription Factor Nurr1

    • Free pre-print version: Loading...

      Authors: Daniel Zaienne; Sabine Willems, Simone Schierle, Jan Heering, Daniel Merk
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01077
      PubDate: Mon, 11 Oct 2021 04:00:00 GMT
       
  • [ASAP] Novel Electrophilic Warhead Targeting a Triple-Negative Breast
           Cancer Driver in Live Cells Revealed by “Inverse Drug Discovery”

    • Free pre-print version: Loading...

      Authors: Youlong Fan; Hongfei Si, Zhang Zhang, Liang Zhong, Hongyan Sun, Chengjun Zhu, Zhibin Yin, Huilin Li, Guanghui Tang, Shao Q. Yao, Pinghua Sun, Zhi-Min Zhang, Ke Ding, Zhengqiu Li△
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.0c02024
      PubDate: Fri, 08 Oct 2021 04:00:00 GMT
       
  • [ASAP] Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular
           Mechanisms Underpinning Ligand Binding and Receptor Oligomerization

    • Free pre-print version: Loading...

      Authors: Giacomo Rossino; Marta Rui, Pasquale Linciano, Daniela Rossi, Massimo Boiocchi, Marco Peviani, Elena Poggio, Daniela Curti, Dirk Schepmann, Bernhard Wünsch, Mariela González-Avendaño, Ariela Vergara-Jaque, Julio Caballero, Simona Collina
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00886
      PubDate: Fri, 08 Oct 2021 04:00:00 GMT
       
  • [ASAP] Small Molecule Kinase Inhibitor Drugs (1995–2021): Medical
           Indication, Pharmacology, and Synthesis

    • Free pre-print version: Loading...

      Authors: Cecilia C. Ayala-Aguilera; Teresa Valero, Álvaro Lorente-Macías, Daniel J. Baillache, Stephen Croke, Asier Unciti-Broceta
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00963
      PubDate: Fri, 08 Oct 2021 04:00:00 GMT
       
  • [ASAP] Indirubin Derivatives as Dual Inhibitors Targeting Cyclin-Dependent
           Kinase and Histone Deacetylase for Treating Cancer

    • Free pre-print version: Loading...

      Authors: Zhuoxian Cao; Fenfen Yang, Jie Wang, Zhicheng Gu, Shuxian Lin, Pan Wang, Jianxiong An, Ting Liu, Yan Li, Yongjun Li, Hening Lin, Yonglong Zhao, Bin He
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01311
      PubDate: Fri, 08 Oct 2021 04:00:00 GMT
       
  • [ASAP] Computational Design of Potent D-Peptide Inhibitors of SARS-CoV-2

    • Free pre-print version: Loading...

      Authors: Pedro A. Valiente; Han Wen, Satra Nim, JinAh Lee, Hyeon Ju Kim, Jinhee Kim, Albert Perez-Riba, Yagya Prasad Paudel, Insu Hwang, Kyun-Do Kim, Seungtaek Kim, Philip M. Kim
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00655
      PubDate: Fri, 08 Oct 2021 04:00:00 GMT
       
  • [ASAP] Antibiotic Conjugates with an Artificial MECAM-Based Siderophore
           Are Potent Agents against Gram-Positive and Gram-Negative Bacterial
           Pathogens

    • Free pre-print version: Loading...

      Authors: Lukas Pinkert; Yi-Hui Lai, Carsten Peukert, Sven-Kevin Hotop, Bianka Karge, Lara Marie Schulze, Jörg Grunenberg, Mark Brönstrup
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01482
      PubDate: Fri, 08 Oct 2021 04:00:00 GMT
       
  • In+Vivo+Efficacy+against+MRSA&rft.title=Journal+of+Medicinal+Chemistry&rft.issn=0022-2623&rft.date=2021&rft.volume=&rft.aulast=Luδ&rft.aufirst=Yanran&rft.au=Yanran+Luδ&rft.au=Sandip+Vibhuteγ,++Linsen+Li,++Antony+Okumuβ,++Steven+C.+Ratiganϵ,++Sheri+Nolan,++Jonathan+L.+Papa,++Chelsea+A.+Mann,++Anthony+Englishα,++Anna+Chen,++Justin+T.+Seffernick,++Bryan+Koci,++Leonard+R.+Duncan,++Brieanna+Roth,++Jason+E.+Cummings,++Richard+A.+Slayden,++Steffen+Lindert,++Craig+A.+McElroy,++Daniel+J.+Wozniak,++Jack+Yalowich,++Mark+J.+Mitton-Fry">[ASAP] Optimization of TopoIV Potency, ADMET Properties, and hERG
           Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase
           Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA

    • Free pre-print version: Loading...

      Authors: Yanran Luδ; Sandip Vibhuteγ, Linsen Li, Antony Okumuβ, Steven C. Ratiganϵ, Sheri Nolan, Jonathan L. Papa, Chelsea A. Mann, Anthony Englishα, Anna Chen, Justin T. Seffernick, Bryan Koci, Leonard R. Duncan, Brieanna Roth, Jason E. Cummings, Richard A. Slayden, Steffen Lindert, Craig A. McElroy, Daniel J. Wozniak, Jack Yalowich, Mark J. Mitton-Fry
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01250
      PubDate: Wed, 06 Oct 2021 04:00:00 GMT
       
  • [ASAP] Multi-Modal Imaging Probe for Glypican-3 Overexpressed in
           Orthotopic Hepatocellular Carcinoma

    • Free pre-print version: Loading...

      Authors: Shuo Feng; Xiaoqing Meng, Zhao Li, Tse-Shao Chang, Xiaoli Wu, Juan Zhou, Bishnu Joshi, Eun-Young Choi, Lili Zhao, Jiye Zhu, Thomas D. Wang
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00697
      PubDate: Thu, 30 Sep 2021 04:00:00 GMT
       
  • [ASAP] A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents
           Neurodegeneration in Parkinson’s Disease

    • Free pre-print version: Loading...

      Authors: Seung-Hwan Kwon; Sangjune Kim, A Yeong Park, Saebom Lee, Changdev Gorakshnath Gadhe, Bo Am Seo, Jong-Sung Park, Suyeon Jo, Yumin Oh, Sin Ho Kweon, Shi-Xun Ma, Wonjoong R. Kim, Misoon Kim, Hyeongjun Kim, Jae Eun Kim, Seulki Lee, Jinhwa Lee, Han Seok Ko
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01022
      PubDate: Tue, 28 Sep 2021 04:00:00 GMT
       
  • [ASAP] Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors

    • Free pre-print version: Loading...

      Authors: Sarah Huff; Indrasena Reddy Kummetha, Shashi Kant Tiwari, Matthew B. Huante, Alex E. Clark, Shaobo Wang, William Bray, Davey Smith, Aaron F. Carlin, Mark Endsley, Tariq M. Rana
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00566
      PubDate: Mon, 27 Sep 2021 04:00:00 GMT
       
  • [ASAP] Noncovalent Interactions with PAMAM and PPI Dendrimers Promote the
           Cellular Uptake and Photodynamic Activity of Rose Bengal: The Role of the
           Dendrimer Structure

    • Free pre-print version: Loading...

      Authors: Krzysztof Sztandera; Micha Gorzkiewicz, Ana Sofia Dias Martins, Lorenzo Pallante, Eric Adriano Zizzi, Marcello Miceli, Mateusz Ba̧tal, Catarina Pinto Reis, Marco A. Deriu, Barbara Klajnert-Maculewicz
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01080
      PubDate: Tue, 21 Sep 2021 04:00:00 GMT
       
  • [ASAP] Update on the Development of MNK Inhibitors as Therapeutic Agents

    • Free pre-print version: Loading...

      Authors: Weijun Xu; Srinivasaraghavan Kannan, Chandra S. Vermaψ, Kassoum Nacro
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00368
      PubDate: Fri, 17 Sep 2021 04:00:00 GMT
       
  • [ASAP] Discovery of Milvexian, a High-Affinity, Orally Bioavailable
           Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy

    • Free pre-print version: Loading...

      Authors: Andrew K. Dilger; Kumar B. Pabbisetty, James R. Corte, Indawati De Lucca, Tianan Fang, Wu Yang, Donald J. P. Pinto, Yufeng Wang, Yeheng Zhu, Arvind Mathur, Jianqing Li, Xiaoping Hou, Daniel Smith, Dawn Sun, Huiping Zhang, Subramaniam Krishnananthan, Dauh-Rurng Wu, Joseph E. Myers, Jr., Steven Sheriff, Karen A. Rossi, Silvi Chacko, Joanna J. Zheng, Michael A. Galella, Theresa Ziemba, Elizabeth A. Dierks, Jeffrey M. Bozarth, Yiming Wu, Earl Crain, Pancras C. Wong, Joseph M. Luettgen, Ruth R. Wexler, William R. Ewing
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00613
      PubDate: Wed, 08 Sep 2021 04:00:00 GMT
       
  • [ASAP] Searching Geometric Patterns in Protein Binding Sites and Their
           Application to Data Mining in Protein Kinase Structures

    • Free pre-print version: Loading...

      Authors: Joel Graef; Christiane Ehrt, Konrad Diedrich, Martin Poppinga, Norbert Ritter, Matthias Rarey
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01046
      PubDate: Tue, 07 Sep 2021 04:00:00 GMT
       
  • [ASAP] Targeting the Nuclear Receptor-Binding SET Domain Family of Histone
           Lysine Methyltransferases for Cancer Therapy: Recent Progress and
           Perspectives

    • Free pre-print version: Loading...

      Authors: Aarajana Shrestha; Nayeon Kim, Su-Jeong Lee, Yong Hyun Jeon, Ji-Joon Song, Hongchan An, Sung Jin Cho, Tara Man Kadayat, Jungwook Chin
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c01116
      PubDate: Tue, 07 Sep 2021 04:00:00 GMT
       
  • [ASAP] Chemical Probes for Understudied Kinases: Challenges and
           Opportunities

    • Free pre-print version: Loading...

      Authors: Ricardo A. M. Serafim; Jonathan M. Elkins, William J. Zuercher, Stefan A. Laufer, Matthias Gehringer
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00980
      PubDate: Fri, 03 Sep 2021 04:00:00 GMT
       
  • In+Vivo+Proof+of+Concept&rft.title=Journal+of+Medicinal+Chemistry&rft.issn=0022-2623&rft.date=2021&rft.volume=&rft.aulast=Giglio&rft.aufirst=Javier&rft.au=Javier+Giglio&rft.au=Soledad+Fernandez,++Ana+Martinez,++Maia+Zeni,++Laura+Reyes,++Ana+Rey,++Hugo+Cerecettog">[ASAP] Glycogen Synthase Kinase-3 Maleimide Inhibitors As Potential
           PET-Tracers for Imaging Alzheimer’s Disease: 11C-Synthesis and In Vivo
           Proof of Concept

    • Free pre-print version: Loading...

      Authors: Javier Giglio; Soledad Fernandez, Ana Martinez, Maia Zeni, Laura Reyes, Ana Rey, Hugo Cerecettog
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00769
      PubDate: Tue, 31 Aug 2021 04:00:00 GMT
       
  • [ASAP] Probing the Allosteric Inhibition Mechanism of a Spike Protein
           Using Molecular Dynamics Simulations and Active Compound Identifications

    • Free pre-print version: Loading...

      Authors: Qian Wang; Lin Wang, Yumin Zhang, XiangLei Zhang, Leike Zhang, Weijuan Shang, Fang Bai
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00320
      PubDate: Fri, 20 Aug 2021 04:00:00 GMT
       
  • [ASAP] Structure-Based Optimization of ML300-Derived, Noncovalent
           Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL
           Protease (SARS-CoV-2 3CLpro)

    • Free pre-print version: Loading...

      Authors: Sang Hoon Han; Christopher M. Goins, Tarun Arya, Woo-Jin Shin, Joshua Maw, Alice Hooper, Dhiraj P. Sonawane, Matthew R. Porter, Breyanne E. Bannister, Rachel D. Crouch, A. Abigail Lindsey, Gabriella Lakatos, Steven R. Martinez, Joseph Alvarado, Wendell S. Akers, Nancy S. Wang, Jae U. Jung, Jonathan D. Macdonald, Shaun R. Stauffer
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00598
      PubDate: Wed, 04 Aug 2021 04:00:00 GMT
       
  • [ASAP] Why All the Fury over Furin'

    • Free pre-print version: Loading...

      Authors: Essam Eldin A. Osman; Alnawaz Rehemtulla, Nouri Neamati
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00518
      PubDate: Mon, 02 Aug 2021 04:00:00 GMT
       
  • [ASAP] Identification of Pyrimidine-Based Lead Compounds for Understudied
           Kinases Implicated in Driving Neurodegeneration

    • Free pre-print version: Loading...

      Authors: David H. Drewry; Joel K. Annor-Gyamfi, Carrow I. Wells, Julie E. Pickett, Verena Dederer, Franziska Preuss, Sebastian Mathea, Alison D. Axtman
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00440
      PubDate: Sun, 01 Aug 2021 04:00:00 GMT
       
  • [ASAP] Synthetic Peptides That Antagonize the Angiotensin-Converting
           Enzyme-2 (ACE-2) Interaction with SARS-CoV-2 Receptor Binding Spike
           Protein

    • Free pre-print version: Loading...

      Authors: Afsaneh Sadremomtaz; Zayana M. Al-Dahmani, Angel J. Ruiz-Moreno, Alessandra Monti, Chao Wang, Taha Azad, John C. Bell, Nunzianna Doti, Marco A. Velasco-Velázquez, Debora de Jong, Jrgen de Jonge, Jolanda Smit, Alexander Dömling, Harry van Goor, Matthew R. Groves
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00477
      PubDate: Fri, 30 Jul 2021 04:00:00 GMT
       
  • [ASAP] Molecular Plasticity of Crystalline CK2α′ Leads to KN2, a
           Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity

    • Free pre-print version: Loading...

      Authors: Dirk Lindenblatt; Violetta Applegate, Anna Nickelsen, Merlin Klußmann, Ines Neundorf, Claudia Götz, Joachim Jose, Karsten Niefind
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00063
      PubDate: Thu, 29 Jul 2021 04:00:00 GMT
       
  • [ASAP] Emerging Approaches to Overcome Acquired Drug Resistance Obstacles
           to Osimertinib in Non-Small-Cell Lung Cancer

    • Free pre-print version: Loading...

      Authors: Matin Shaikh; Yashodeep Shinde, Rahul Pawara, Malleshappa Noolvi, Sanjay Surana, Iqrar Ahmad, Harun Patel
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00876
      PubDate: Thu, 29 Jul 2021 04:00:00 GMT
       
  • [ASAP] 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as
           Anti-SARS-CoV-2 Agents

    • Free pre-print version: Loading...

      Authors: Sho Konno; Kiyotaka Kobayashi, Miki Senda, Yuta Funai, Yuta Seki, Ikumi Tamai, Laura Schäkel, Kyousuke Sakata, Thanigaimalai Pillaiyar, Akihiro Taguchi, Atsuhiko Taniguchi, Michael Gütschow, Christa E. Müller, Koh Takeuchi, Mikako Hirohama, Atsushi Kawaguchi, Masaki Kojima, Toshiya Senda, Yoshiyuki Shirasaka, Wataru Kamitani, Yoshio Hayashi
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00665
      PubDate: Tue, 27 Jul 2021 04:00:00 GMT
       
  • in+Vitro+Biological+Stability&rft.title=Journal+of+Medicinal+Chemistry&rft.issn=0022-2623&rft.date=2021&rft.volume=&rft.aulast=Bai&rft.aufirst=Bing&rft.au=Bing+Bai&rft.au=Alexandr+Belovodskiy,++Mostofa+Hena,++Appan+Srinivas+Kandadai,++Michael+A.+Joyce,++Holly+A.+Saffran,++Justin+A.+Shields,++Muhammad+Bashir+Khan,++Elena+Arutyunova,++Jimmy+Lu,++Sardeev+K.+Bajwa,++Darren+Hockman,++Conrad+Fischer,++Tess+Lamer,++Wayne+Vuong,++Marco+J.+van+Belkum,++Zhengxian+Gu,++Fusen+Lin,++Yanhua+Du,++Jia+Xu,++Mohammad+Rahim▽,++Howard+S.+Young,++John+C.+Vederas,++D.+Lorne+Tyrrell,++M.+Joanne+Lemieux,++James+A.+Nieman">[ASAP] Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered
           Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus
           Antiviral Activity, and in Vitro Biological Stability

    • Free pre-print version: Loading...

      Authors: Bing Bai; Alexandr Belovodskiy, Mostofa Hena, Appan Srinivas Kandadai, Michael A. Joyce, Holly A. Saffran, Justin A. Shields, Muhammad Bashir Khan, Elena Arutyunova, Jimmy Lu, Sardeev K. Bajwa, Darren Hockman, Conrad Fischer, Tess Lamer, Wayne Vuong, Marco J. van Belkum, Zhengxian Gu, Fusen Lin, Yanhua Du, Jia Xu, Mohammad Rahim▽, Howard S. Young, John C. Vederas, D. Lorne Tyrrell, M. Joanne Lemieux, James A. Nieman
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00616
      PubDate: Fri, 09 Jul 2021 04:00:00 GMT
       
  • [ASAP] Addressing a Trapped High-Energy Water: Design and Synthesis of
           Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors
           

    • Free pre-print version: Loading...

      Authors: Stanislav Andreev⧫; Tatu Pantsar⧫, Roberta Tesch, Niclas Kahlke, Ahmed El-Gokha, Francesco Ansideri, Lukas Grätz, Jenny Romasco, Giulia Sita, Christian Geibel, Michael Lämmerhofer, Andrea Tarozzi, Stefan Knapp, Stefan A. Laufer☆, Pierre Koch
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.0c02146
      PubDate: Fri, 02 Jul 2021 04:00:00 GMT
       
  • [ASAP] In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to
           Allosterically Inhibit the Kinase Activity of mTORC1

    • Free pre-print version: Loading...

      Authors: Raef Shams; Akihiro Matsukawa, Yukari Ochi, Yoshihiro Ito, Hideyuki Miyatake
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00536
      PubDate: Wed, 30 Jun 2021 04:00:00 GMT
       
  • [ASAP] Kinases as Potential Therapeutic Targets for Anti-coronaviral
           Therapy

    • Free pre-print version: Loading...

      Authors: Thanigaimalai Pillaiyar; Stefan Laufer
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00335
      PubDate: Thu, 03 Jun 2021 04:00:00 GMT
       
  • [ASAP] Design and Synthesis of Highly Selective Brain Penetrant p38α
           Mitogen-Activated Protein Kinase Inhibitors

    • Free pre-print version: Loading...

      Authors: Niklas M. Tormählen; Mariella Martorelli, Annette Kuhn, Florian Maier, Jamil Guezguez, Michael Burnet, Wolfgang Albrecht, Stefan A. Laufer, Pierre Koch
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.0c01773
      PubDate: Tue, 11 May 2021 04:00:00 GMT
       
  • [ASAP] Kinase Inhibitors as Underexplored Antiviral Agents

    • Free pre-print version: Loading...

      Authors: Javier García-Cárceles; Elena Caballero, Carmen Gil, Ana Martínez
      Abstract: TOC GraphicJournal of Medicinal Chemistry
      DOI : 10.1021/acs.jmedchem.1c00302
      PubDate: Mon, 10 May 2021 04:00:00 GMT
       
 
JournalTOCs
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Email: journaltocs@hw.ac.uk
Tel: +00 44 (0)131 4513762
 


Your IP address: 3.236.232.99
 
Home (Search)
API
About JournalTOCs
News (blog, publications)
JournalTOCs on Twitter   JournalTOCs on Facebook

JournalTOCs © 2009-