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J. of Integrated OMICS     Open Access   (SJR: 0.113, CiteScore: 0)
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Journal of Integrated OMICS
Journal Prestige (SJR): 0.113
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2182-0287 - ISSN (Online) 2182-0287
Published by Proteomass Homepage  [1 journal]
  • Comparative analyses of the complete mitochondrial genomes of the two
           filarial worms Wuchereria bancrofti & Brugia malayi with Caenorhabditis
           elegans

    • Authors: Saranya Joshi, Lokesh Kumar, Kanchan Rauthan, Sudhir Kumar
      Abstract: Wuchereria bancrofti and Brugia malayi are the filarial worms belonging to phylum Nematoda and cause lymphatic filariasis (LF) disease in humans. W. bancrofti and B. malayi are Wolbachia dependent organisms while C. elegans is free living Wolbachia independent nematode. In order to investigate the conserved regions present in the mitochondrial genome of these organisms, the complete mitochondrial (mt) genomes of W. bancrofti and B. malayi having size 13,636 bp and 13,657 bp in length, respectively are compared with C. elegans (13794 bp). These mt genomes were similar to each other in respect of their size, AT content and encode the same 12 PCGs (nad1–6, nad4L, cytb, cox1–3, and atp6). Complete mt genome alignment identified 13 conserved regions in each of the organisms with some of these regions unique only to one organism. Phylogenetic analysis using the mt genome showed a close relationship between W. bancrofti and B. malayi but showed a common early ancestor with the C. elegans emphasizing an early evolutionary divergence. 
      PubDate: 2022-10-03
      DOI: 10.5584/jiomics.v12i1.212
      Issue No: Vol. 12, No. 1 (2022)
       
  • Prescriptomics: the next frontier in medicine

    • Authors: José L. Capelo, Carlos Lodeiro, Rajiv Dhir, Nataly Kravchenko-Balasha, Hugo M. Santos
      PubDate: 2022-05-23
      DOI: 10.5584/jiomics.v12i1.211
      Issue No: Vol. 12, No. 1 (2022)
       
 
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