Publisher: Universidad de Concepción   (Total: 4 journals)   [Sort by number of followers]

Showing 1 - 4 of 4 Journals sorted alphabetically
Acta Literaria     Open Access   (Followers: 4, SJR: 0.1, CiteScore: 0)
Atenea (Concepción)     Open Access   (SJR: 0.112, CiteScore: 0)
J. of Oral Research     Open Access   (Followers: 1, SJR: 0.126, CiteScore: 0)
Revista Academia & Negocios     Open Access  
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Journal of Oral Research
Journal Prestige (SJR): 0.126
Number of Followers: 1  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0719-2460 - ISSN (Online) 0719-2479
Published by Universidad de Concepción Homepage  [4 journals]
  • Salami publications, predatory magazines, and other vices against the
           academic curriculum

    • Authors: Antonieta Pérez-Flores
      Pages: 1 - 4
      PubDate: 2022-12-31
      DOI: 10.17126/joralres.2022.070
      Issue No: Vol. 11, No. 6 (2022)
  • Does systemic anticancer gemcitabine compromise oral soft tissue wound

    • Authors: Alyaa I. Naser, Rayan S. Hamed, Ghada A. Taqa
      Pages: 1 - 11
      Abstract: Background: Numerous types of cancer are of substantial medical and social concern, posing a major challenge to modern medicine. Chemotherapeutic drugs include the use of nucleosides, which are composed of nucleic acid and sugar.
      Objective: This study aims to assess the impact of systemic chemotherapeutic drugs at a therapeutic dose on the wound healing process of the oral mucosa.
      Material and Methods: 30 healthy rats were randomly divided into two main groups based on the study material, 15 rats in each group. Group A (control) was given a single dose of normal saline (1ml/kg, intraperitoneal), and Group B (study) a single injection of gemcitabine (50 mg /Kg, intraperitoneal). After anesthesia, a full-thickness soft tissue incision (0.5 cm length) on the right side of the buccal mucosa was made in the animals of both groups. Each group was subdivided according to the time of sacrifice into 3, 7, 14 days after surgery, at the end of the experimental periods, specimens were collected for histopathological study, and samples of blood were obtained from retro-orbital venous plexus and collected in microfuge tubes and levels of antioxidant enzymes were measured by ELISA. The data were analyzed statistically at a 0.05 level of significance.
      Results: Gemcitabine delayed the onset of wound cascade (inflammation and re-epithelization) which lead to worsening healing of the oral tissue; it also resulted in a decrease of the antioxidant activity of glutathione peroxidase and catalase, as well as activated caspase 3, which induces cell apoptosis.
      Conclusion: Gemcitabine showed negative feedback on oral tissue wound healing through delayed wound healing cascade and by inducing apoptosis.
      PubDate: 2022-12-31
      DOI: 10.17126/joralres.2022.056
      Issue No: Vol. 11, No. 6 (2022)
  • Effects of using different root canal sealers and protocols for cleaning
           intraradicular dentin on the bond strength of a composite resin used to
           reinforce weakened roots.

    • Authors: Luiz Pascoal Vansan, Ricardo Machado, Celso Bernardes de Souza, Ricardo Gariba, Antônio Miranda da Cruz, Cinara Muniz, Jardel Francisco Mazzi-Chaves, Lucas da Fonseca Roberti Garcia
      Pages: 1 - 9
      Abstract: Background: This study evaluated the effects of using different root canal sealers and protocols for cleaning intraradicular dentin on the bond strength of a composite resin used to reinforce weakened roots.
      Material and Methods: Sixty-four roots of extracted human maxillary canines were weakened, prepared and filled with two different endodontic sealers (Endofill and AH Plus). In half of the sample, set aside for each respective sealer, excess filling material was cleaned. In the other half, the weakened areas were not cleaned, and the excess of sealer was spread on the intraradicular dentin. Intentionally worn areas inside each root were restored with a microhybrid light-cure composite resin (Z100) to reinforce them, with and without acid etching. Prefabricated metal posts were fixed with a dual resin cement (RelyX ARC), and the specimens were submitted to a pull-out test. Statistical analysis was performed by means of Shapiro-Wilk, analysis of variance (one-way ANOVA) and Tukey-Kramer tests (p<0.05).
      Results: The groups filled with Endofill (GI, GII, GIII, GIV) had the lowest bond strength values, which were similar among each other (p>0.05).The greatest bond strength values were observed in roots filled with AH Plus (GV, GVI, GVII, GVIII), mainly without cleaning of the weakened areas, and followed by acid etching (GVII), and also with cleaning of the weakened areas, however, with no acid etching (GVI) (p<0.05).
      Conclusion: The greatest bond strength values were observed in roots filled with AH Plus; (1) without cleaning of the weakened areas and with acid etching, and; (2) with cleaning of the weakened areas, but without acid etching.
      PubDate: 2022-12-30
      DOI: 10.17126/joralres.2022.063
      Issue No: Vol. 11, No. 6 (2022)
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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