Publisher: Cambridge University Press   (Total: 388 journals)

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Showing 201 - 388 of 388 Journals sorted alphabetically
J. of British Studies     Full-text available via subscription   (Followers: 34, SJR: 0.246, CiteScore: 0)
J. of Child Language     Hybrid Journal   (Followers: 30, SJR: 1.035, CiteScore: 2)
J. of Chinese History / 中國歷史學刊     Hybrid Journal   (Followers: 1)
J. of Classics Teaching     Open Access  
J. of Clinical and Translational Science     Open Access  
J. of Dairy Research     Full-text available via subscription   (Followers: 8, SJR: 0.573, CiteScore: 1)
J. of Demographic Economics     Hybrid Journal   (Followers: 4, SJR: 1.227, CiteScore: 1)
J. of Developmental Origins of Health and Disease     Hybrid Journal   (Followers: 2, SJR: 0.843, CiteScore: 2)
J. of Diagnostic Radiography and Imaging     Hybrid Journal   (Followers: 4)
J. of East Asian Studies     Hybrid Journal   (Followers: 17, SJR: 0.59, CiteScore: 1)
J. of Ecclesiastical History     Hybrid Journal   (Followers: 20, SJR: 0.138, CiteScore: 0)
J. of Economic History     Full-text available via subscription   (Followers: 47, SJR: 1.82, CiteScore: 2)
J. of Experimental Political Science     Full-text available via subscription   (Followers: 7, SJR: 2.526, CiteScore: 2)
J. of Financial and Quantitative Analysis     Full-text available via subscription   (Followers: 52, SJR: 3.636, CiteScore: 2)
J. of Fluid Mechanics     Hybrid Journal   (Followers: 198, SJR: 1.591, CiteScore: 3)
J. of French Language Studies     Hybrid Journal   (Followers: 7, SJR: 0.163, CiteScore: 0)
J. of Functional Programming     Hybrid Journal   (Followers: 1, SJR: 0.458, CiteScore: 1)
J. of Germanic Linguistics     Full-text available via subscription   (Followers: 8, SJR: 0.157, CiteScore: 0)
J. of Global History     Full-text available via subscription   (Followers: 31, SJR: 0.34, CiteScore: 1)
J. of Hellenic Studies     Full-text available via subscription   (Followers: 19, SJR: 0.146, CiteScore: 0)
J. of Helminthology     Hybrid Journal   (Followers: 2, SJR: 0.553, CiteScore: 1)
J. of Hospitality and Tourism Management     Full-text available via subscription   (Followers: 14, SJR: 0.949, CiteScore: 2)
J. of Institutional Economics     Hybrid Journal   (Followers: 15, SJR: 0.978, CiteScore: 2)
J. of K-Theory     Full-text available via subscription  
J. of Laryngology & Otology     Hybrid Journal   (Followers: 21, SJR: 0.495, CiteScore: 1)
J. of Latin American Studies     Hybrid Journal   (Followers: 35, SJR: 0.34, CiteScore: 1)
J. of Law and Religion     Full-text available via subscription   (Followers: 10, SJR: 0.115, CiteScore: 0)
J. of Linguistic Geography     Full-text available via subscription   (Followers: 1)
J. of Linguistics     Hybrid Journal   (Followers: 18, SJR: 0.451, CiteScore: 1)
J. of Management & Organization     Full-text available via subscription   (Followers: 354, SJR: 0.543, CiteScore: 1)
J. of Mechanics     Hybrid Journal   (Followers: 21, SJR: 0.303, CiteScore: 1)
J. of Modern African Studies     Hybrid Journal   (Followers: 21, SJR: 0.606, CiteScore: 1)
J. of Navigation     Hybrid Journal   (Followers: 262, SJR: 0.493, CiteScore: 2)
J. of Nutritional Science     Open Access   (Followers: 4, SJR: 0.984, CiteScore: 2)
J. of Pacific Rim Psychology     Hybrid Journal   (Followers: 1, SJR: 0.33, CiteScore: 1)
J. of Paleontology     Hybrid Journal   (Followers: 11, SJR: 0.882, CiteScore: 2)
J. of Pension Economics & Finance     Hybrid Journal   (Followers: 7, SJR: 0.931, CiteScore: 1)
J. of Plasma Physics     Hybrid Journal   (Followers: 23, SJR: 0.441, CiteScore: 1)
J. of Psychiatric Intensive Care     Hybrid Journal   (Followers: 8)
J. of Psychologists and Counsellors in Schools     Full-text available via subscription   (Followers: 8, SJR: 0, CiteScore: 1)
J. of Public Policy     Hybrid Journal   (Followers: 27, SJR: 0.542, CiteScore: 1)
J. of Race, Ethnicity, and Politics     Full-text available via subscription   (Followers: 4)
J. of Radiotherapy in Practice     Hybrid Journal   (Followers: 7, SJR: 0.16, CiteScore: 0)
J. of Relationships Research     Hybrid Journal   (Followers: 5, SJR: 0.294, CiteScore: 0)
J. of Roman Archaeology     Hybrid Journal   (Followers: 23, SJR: 0.341, CiteScore: 1)
J. of Roman Studies     Full-text available via subscription   (Followers: 22, SJR: 0.182, CiteScore: 0)
J. of Smoking Cessation     Hybrid Journal   (Followers: 6, SJR: 0.411, CiteScore: 0)
J. of Social Policy     Hybrid Journal   (Followers: 42, SJR: 1.063, CiteScore: 2)
J. of Southeast Asian Studies     Full-text available via subscription   (Followers: 12, SJR: 0.14, CiteScore: 0)
J. of Symbolic Logic     Hybrid Journal   (Followers: 1, SJR: 1.057, CiteScore: 1)
J. of the American Philosophical Association     Hybrid Journal   (SJR: 0.857, CiteScore: 1)
J. of the Australian Mathematical Society     Full-text available via subscription   (SJR: 0.46, CiteScore: 1)
J. of the Gilded Age and Progressive Era     Full-text available via subscription   (Followers: 8, SJR: 0.192, CiteScore: 0)
J. of the History of Economic Thought     Full-text available via subscription   (Followers: 15, SJR: 0.784, CiteScore: 1)
J. of the Institute of Mathematics of Jussieu     Hybrid Journal   (SJR: 2.393, CiteScore: 1)
J. of the Intl. Neuropsychological Society     Hybrid Journal   (Followers: 15, SJR: 1.408, CiteScore: 3)
J. of the Intl. Phonetic Association     Full-text available via subscription   (Followers: 2, SJR: 0.27, CiteScore: 1)
J. of the Marine Biological Association of the UK     Hybrid Journal   (Followers: 23, SJR: 0.548, CiteScore: 1)
J. of the Royal Asiatic Society     Hybrid Journal   (Followers: 15, SJR: 0.121, CiteScore: 0)
J. of the Society for American Music     Hybrid Journal   (Followers: 10, SJR: 0.199, CiteScore: 0)
J. of Tropical Ecology     Hybrid Journal   (Followers: 14, SJR: 0.626, CiteScore: 1)
J. of Tropical Psychology     Hybrid Journal   (Followers: 1)
J. of Wine Economics     Full-text available via subscription   (Followers: 5)
Japanese J. of Political Science     Hybrid Journal   (Followers: 8, SJR: 0.372, CiteScore: 1)
Kantian Review     Full-text available via subscription   (Followers: 3)
Knowledge Engineering Review     Hybrid Journal   (Followers: 2, SJR: 0.357, CiteScore: 2)
Language and Cognition     Hybrid Journal   (Followers: 22)
Language in Society     Hybrid Journal   (Followers: 23, SJR: 1.466, CiteScore: 2)
Language Teaching     Hybrid Journal   (Followers: 33, SJR: 1.233, CiteScore: 2)
Language Variation and Change     Hybrid Journal   (Followers: 10, SJR: 0.854, CiteScore: 1)
Laser and Particle Beams     Hybrid Journal   (Followers: 2, SJR: 0.497, CiteScore: 1)
Law and History Review     Full-text available via subscription   (Followers: 15, SJR: 0.184, CiteScore: 0)
Legal Information Management     Hybrid Journal   (Followers: 10)
Legal Theory     Hybrid Journal   (Followers: 14, SJR: 0.484, CiteScore: 1)
Leiden J. of Intl. Law     Hybrid Journal   (Followers: 40, SJR: 0.482, CiteScore: 0)
Libyan Studies     Hybrid Journal   (Followers: 1, SJR: 0.111, CiteScore: 0)
LMS J. of Computation and Mathematics     Free   (SJR: 0.229, CiteScore: 1)
Macroeconomic Dynamics     Hybrid Journal   (Followers: 25, SJR: 1.169, CiteScore: 1)
Management and Organization Review     Hybrid Journal   (Followers: 12, SJR: 0.816, CiteScore: 2)
Mathematical Proceedings of the Cambridge Philosophical Society     Full-text available via subscription   (Followers: 2, SJR: 1.086, CiteScore: 1)
Mathematical Structures in Computer Science     Hybrid Journal   (Followers: 4, SJR: 0.298, CiteScore: 1)
Medical History     Hybrid Journal   (Followers: 8, SJR: 0.417, CiteScore: 1)
Microscopy and Microanalysis     Full-text available via subscription   (Followers: 2, SJR: 0.292, CiteScore: 0)
Modern Asian Studies     Hybrid Journal   (Followers: 16, SJR: 0.397, CiteScore: 0)
Modern Intellectual History     Hybrid Journal   (Followers: 18, SJR: 0.218, CiteScore: 0)
MRS Communications     Hybrid Journal   (SJR: 1.443, CiteScore: 3)
MRS Energy & Sustainability - A Review J.     Full-text available via subscription  
Nagoya Mathematical J.     Hybrid Journal   (SJR: 0.892, CiteScore: 1)
Natural Language Engineering     Hybrid Journal   (Followers: 4, SJR: 0.264, CiteScore: 1)
Netherlands J. of Geosciences     Hybrid Journal   (SJR: 0.285, CiteScore: 1)
Netherlands Yearbook of Intl. Law     Full-text available via subscription   (Followers: 16, SJR: 0.196, CiteScore: 0)
Network Science     Hybrid Journal   (Followers: 5, SJR: 0.461, CiteScore: 1)
Neuron Glia Biology     Hybrid Journal  
New Perspectives on Turkey     Full-text available via subscription   (Followers: 3, SJR: 0.111, CiteScore: 0)
New Surveys in the Classics     Full-text available via subscription   (Followers: 3)
New Testament Studies     Hybrid Journal   (Followers: 34, SJR: 0.316, CiteScore: 0)
New Theatre Quarterly     Hybrid Journal   (Followers: 15, SJR: 0.132, CiteScore: 0)
Nineteenth-Century Music Review     Hybrid Journal   (Followers: 6, SJR: 0.1, CiteScore: 0)
Nordic J. of Linguistics     Hybrid Journal   (Followers: 8, SJR: 0.156, CiteScore: 0)
Numerical Mathematics : Theory, Methods and Applications     Full-text available via subscription  
Nurse Prescriber     Full-text available via subscription   (Followers: 5)
Nutrition Research Reviews     Hybrid Journal   (Followers: 13, SJR: 1.756, CiteScore: 5)
Organised Sound     Hybrid Journal   (Followers: 8, SJR: 0.271, CiteScore: 0)
Oryx     Hybrid Journal   (Followers: 19, SJR: 0.981, CiteScore: 2)
Paleobiology     Full-text available via subscription   (Followers: 6, SJR: 1.563, CiteScore: 3)
Palliative & Supportive Care     Hybrid Journal   (Followers: 35, SJR: 0.611, CiteScore: 1)
Papers of the British School at Rome     Full-text available via subscription   (Followers: 19, SJR: 0.13, CiteScore: 0)
Parasitology     Hybrid Journal   (Followers: 4, SJR: 1.194, CiteScore: 2)
Parasitology Open     Open Access  
Personality Neuroscience     Open Access  
Perspectives on Politics     Full-text available via subscription   (Followers: 42, SJR: 2.075, CiteScore: 2)
Philosophy     Full-text available via subscription   (Followers: 14, SJR: 0.331, CiteScore: 0)
Phonology     Hybrid Journal   (Followers: 9, SJR: 0.623, CiteScore: 1)
Plainsong and Medieval Music     Hybrid Journal   (Followers: 8, SJR: 0.114, CiteScore: 0)
Plant Genetic Resources     Hybrid Journal   (Followers: 3, SJR: 0.353, CiteScore: 1)
Polar Record     Hybrid Journal   (Followers: 2, SJR: 0.313, CiteScore: 1)
Political Analysis     Hybrid Journal   (Followers: 62, SJR: 4.531, CiteScore: 3)
Political Science Research and Methods     Full-text available via subscription   (Followers: 24)
Politics & Gender     Full-text available via subscription   (Followers: 25, SJR: 0.861, CiteScore: 1)
Politics and Religion     Full-text available via subscription   (Followers: 9, SJR: 0.541, CiteScore: 1)
Popular Music     Hybrid Journal   (Followers: 20, SJR: 0.216, CiteScore: 0)
Powder Diffraction     Full-text available via subscription   (Followers: 1, SJR: 0.319, CiteScore: 1)
Prehospital and Disaster Medicine     Full-text available via subscription   (Followers: 9, SJR: 0.462, CiteScore: 1)
Primary Health Care Research & Development     Open Access   (Followers: 18, SJR: 0.52, CiteScore: 1)
Probability in the Engineering and Informational Sciences     Hybrid Journal   (Followers: 1, SJR: 0.406, CiteScore: 1)
Proceedings of the Edinburgh Mathematical Society     Hybrid Journal   (SJR: 0.695, CiteScore: 1)
Proceedings of the Intl. Astronomical Union     Full-text available via subscription   (Followers: 2, SJR: 0.117, CiteScore: 0)
Proceedings of the Nutrition Society     Hybrid Journal   (Followers: 8, SJR: 1.373, CiteScore: 4)
Proceedings of the Prehistoric Society     Hybrid Journal   (Followers: 9)
Proceedings of the Royal Society of Edinburgh Section A Mathematics     Full-text available via subscription   (SJR: 1.506, CiteScore: 1)
Progress in Neurotherapeutics and Neuropsychopharmacology     Full-text available via subscription  
PS: Political Science & Politics     Full-text available via subscription   (Followers: 38, SJR: 0.665, CiteScore: 1)
Psychological Medicine     Hybrid Journal   (Followers: 19, SJR: 3.274, CiteScore: 5)
Public Health Nutrition     Hybrid Journal   (Followers: 26, SJR: 1.122, CiteScore: 2)
Publications of the Astronomical Society of Australia     Hybrid Journal   (Followers: 2, SJR: 1.237, CiteScore: 2)
Quarterly Reviews of Biophysics     Hybrid Journal   (Followers: 3, SJR: 3.282, CiteScore: 6)
Quaternary Research     Full-text available via subscription   (Followers: 19, SJR: 1.216, CiteScore: 2)
Queensland Review     Full-text available via subscription   (SJR: 0.101, CiteScore: 0)
Radiocarbon     Hybrid Journal   (Followers: 9, SJR: 0.959, CiteScore: 2)
Ramus : Critical Studies in Greek and Roman Literature     Hybrid Journal   (Followers: 5, SJR: 0.201, CiteScore: 0)
ReCALL     Hybrid Journal   (Followers: 4, SJR: 2.813, CiteScore: 3)
Religious Studies     Hybrid Journal   (Followers: 12, SJR: 0.172, CiteScore: 0)
Renewable Agriculture and Food Systems     Hybrid Journal   (Followers: 15, SJR: 0.593, CiteScore: 2)
Review of Intl. Studies     Full-text available via subscription   (Followers: 27, SJR: 1.63, CiteScore: 2)
Review of Middle East Studies     Full-text available via subscription   (Followers: 10, SJR: 0.101, CiteScore: 0)
Review of Politics     Full-text available via subscription   (Followers: 5, SJR: 0.119, CiteScore: 0)
Review of Symbolic Logic     Full-text available via subscription   (Followers: 2, SJR: 1.049, CiteScore: 1)
Reviews in Clinical Gerontology     Hybrid Journal   (Followers: 5)
Revista de Historia Económica     Full-text available via subscription   (Followers: 1, SJR: 0.221, CiteScore: 0)
Revista Internacional de la Cruz Roja     Full-text available via subscription   (Followers: 2)
Robotica     Hybrid Journal   (Followers: 3, SJR: 0.375, CiteScore: 1)
Royal Institute of Philosophy Supplements     Full-text available via subscription   (Followers: 4)
Rural History     Hybrid Journal   (Followers: 14, SJR: 0.145, CiteScore: 0)
Science in Context     Hybrid Journal   (Followers: 4, SJR: 0.265, CiteScore: 0)
Scottish J. of Theology     Hybrid Journal   (Followers: 38, SJR: 0.177, CiteScore: 0)
Seed Science Research     Hybrid Journal   (Followers: 2, SJR: 0.95, CiteScore: 2)
Slavic Review     Hybrid Journal   (Followers: 9, SJR: 0.395, CiteScore: 1)
Social Philosophy and Policy     Full-text available via subscription   (Followers: 22, SJR: 0.253, CiteScore: 1)
Social Policy and Society     Hybrid Journal   (Followers: 196, SJR: 0.653, CiteScore: 1)
Social Science History     Full-text available via subscription   (Followers: 17, SJR: 0.2, CiteScore: 0)
Spanish J. of Psychology     Hybrid Journal  
Studies in American Political Development     Hybrid Journal   (Followers: 6, SJR: 0.204, CiteScore: 0)
Studies in Church History     Full-text available via subscription   (Followers: 1)
Studies in Second Language Acquisition     Hybrid Journal   (Followers: 41, SJR: 1.516, CiteScore: 2)
Tempo     Hybrid Journal   (Followers: 2, SJR: 0.151, CiteScore: 0)
Thalamus & Related Systems     Full-text available via subscription  
The Americas : A Quarterly Review of Latin American History     Full-text available via subscription   (Followers: 6, SJR: 0.305, CiteScore: 0)
The Lichenologist     Hybrid Journal   (Followers: 5, SJR: 1.113, CiteScore: 2)
The Mathematical Gazette     Full-text available via subscription   (Followers: 1)
Theatre Research Intl.     Full-text available via subscription   (Followers: 15, SJR: 0.204, CiteScore: 0)
Theatre Survey     Full-text available via subscription   (Followers: 11, SJR: 0.121, CiteScore: 0)
Theory and Practice of Logic Programming     Hybrid Journal   (Followers: 3, SJR: 0.524, CiteScore: 2)
Think     Full-text available via subscription   (Followers: 6)
TRaNS : Trans-Regional-and-National Studies of Southeast Asia     Full-text available via subscription   (Followers: 6, SJR: 0.192, CiteScore: 0)
Transactions of the Royal Historical Society     Hybrid Journal   (Followers: 15, SJR: 0.419, CiteScore: 0)
Transnational Environmental Law     Hybrid Journal   (Followers: 5, SJR: 0.498, CiteScore: 1)
Twentieth-century music     Hybrid Journal   (Followers: 4, SJR: 0.453, CiteScore: 1)
Twin Research and Human Genetics     Full-text available via subscription   (SJR: 0.72, CiteScore: 1)
Urban History     Hybrid Journal   (Followers: 19, SJR: 0.358, CiteScore: 0)
Utilitas     Hybrid Journal   (Followers: 8, SJR: 0.712, CiteScore: 0)
Victorian Literature and Culture     Hybrid Journal   (Followers: 21, SJR: 0.163, CiteScore: 0)
Visual Neuroscience     Hybrid Journal   (Followers: 7, SJR: 1.012, CiteScore: 2)
Wireless Power Transfer     Full-text available via subscription   (Followers: 4)
World Politics     Hybrid Journal   (Followers: 219, SJR: 6.544, CiteScore: 4)
World Trade Review     Full-text available via subscription   (Followers: 17, SJR: 0.591, CiteScore: 1)
World's Poultry Science J.     Full-text available via subscription   (Followers: 5, SJR: 0.559, CiteScore: 1)
Yearbook of Intl. Humanitarian Law     Full-text available via subscription   (Followers: 9, SJR: 0.107, CiteScore: 0)
Zygote     Hybrid Journal   (Followers: 1, SJR: 0.387, CiteScore: 1)

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Similar Journals
Journal Cover
Journal Prestige (SJR): 1.194
Citation Impact (citeScore): 2
Number of Followers: 4  
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0031-1820 - ISSN (Online) 1469-8161
Published by Cambridge University Press Homepage  [388 journals]
  • PAR volume 147 issue 9 Cover and Front matter
    • PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000876
      Issue No: Vol. 147, No. 9 (2020)
  • PAR volume 147 issue 9 Cover and Back matter
    • PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000888
      Issue No: Vol. 147, No. 9 (2020)
  • Filarial worms: a systematic review and meta-analysis of diversity in
           animals from Iran with emphasis on human cases
    • Authors: Ezatollah Ghasemi; Sadegh Shamsinia, Ali Taghipour, Davood Anvari, Saeed Bahadory, Seyyed Ali Shariatzadeh, Bahareh Kordi, Hamidreza Majidiani, Hassan Borji, MohammadReza Chaechi Nosrati, Ali Yousefi, Morteza Shams
      Pages: 909 - 921
      Abstract: Current systematic review and meta-analysis demonstrate the prevalence reports of filariasis in animals in Iran along with human cases. Studies were screened, relevant papers were selected and the random-effect model was used by forest plot with 95% confidence interval (CI). Of 17 records of human case-reports, particularly from Khuzestan province (5 cases), Dirofilaria repens was the most detected parasite (10 cases) with higher involvement of the right eye (7 cases) than other organs. Eleven animal species were reported to be parasitised by filarioids in Iran. The prevalence of Dirofilaria immitis in canids was 14.69% (95% CI: 10.33–19.67), with highest rates (20.92%; 95% CI: 13.84–29.03) in free-ranging dogs. Male (10.07%; 95% CI: 5.10–16.47) and more than 1-year old (20.77%; 95% CI: 8.66–36.42) dogs were more likely to be found infected. The frequency of other filarioids of zoonotic interest was: Acanthocheilonema reconditum in dogs 2.15% (95% CI: 0.71–4.33), Dipetalonema evansi in camels 10.16% (95% CI: 4.73–17.34), Onchocerca cervicalis in horses 3.63% (95% CI: 1.44–6.75%) and Onchocerca fasciata 16.57% (95% CI: 10.12–24.24%) in camels. Still, our knowledge on parasitic filariae in Iran is limited and more investigation is needed in both human and animal populations.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S003118202000058X
      Issue No: Vol. 147, No. 9 (2020)
  • Human African trypanosomiasis: the current situation in endemic regions
           and the risks for non-endemic regions from imported cases
    • Authors: Jiang-Mei Gao; Zheng-Yu Qian, Geoff Hide, De-Hua Lai, Zhao-Rong Lun, Zhong-Dao Wu
      Pages: 922 - 931
      Abstract: Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense and caused devastating epidemics during the 20th century. Due to effective control programs implemented in the last two decades, the number of reported cases has fallen to a historically low level. Although fewer than 977 cases were reported in 2018 in endemic countries, HAT is still a public health problem in endemic regions until it is completely eliminated. In addition, almost 150 confirmed HAT cases were reported in non-endemic countries in the last three decades. The majority of non-endemic HAT cases were reported in Europe, USA and South Africa, due to historical alliances, economic links or geographic proximity to disease-endemic countries. Furthermore, with the implementation of the ‘Belt and Road’ project, sporadic imported HAT cases have been reported in China as a warning sign of tropical diseases prevention. In this paper, we explore and interpret the data on HAT incidence and find no positive correlation between the number of HAT cases from endemic and non-endemic countries. This data will provide useful information for better understanding the imported cases of HAT globally in the post-elimination phase.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000645
      Issue No: Vol. 147, No. 9 (2020)
  • Leishmania+infantum+proteins+to+be+applied+for+the+diagnosis+of+visceral+leishmaniasis+and+human+immunodeficiency+virus+co-infection&rft.title=Parasitology&rft.issn=0031-1820&,+João+A.+Oliveira-da-Silva,+Thaís+T.+O.+Santos,+Grasiele+S.+V.+Tavares,+Lourena+E.+Costa,+Daniela+P.+Lage,+André+Teixeira-Ferreira,+Jonas+Perales,+Ana+Paula+Fernandes,+Ricardo+L.+F.+Moreira,+Mariana+C.+Duarte,+Unaí+Tupinambás,+Rachel+B.+Caligiorne,+Gláucia+F.+Cota,+Eduardo+A.+F.+Coelho,+Fernanda+Ludolf&rft_id=info:doi/10.1017/S0031182020000578">An immunoproteomics approach to identify Leishmania infantum proteins to
           be applied for the diagnosis of visceral leishmaniasis and human
           immunodeficiency virus co-infection
    • Authors: Amanda S. Machado; Fernanda F. Ramos, João A. Oliveira-da-Silva, Thaís T. O. Santos, Grasiele S. V. Tavares, Lourena E. Costa, Daniela P. Lage, André Teixeira-Ferreira, Jonas Perales, Ana Paula Fernandes, Ricardo L. F. Moreira, Mariana C. Duarte, Unaí Tupinambás, Rachel B. Caligiorne, Gláucia F. Cota, Eduardo A. F. Coelho, Fernanda Ludolf
      Pages: 932 - 939
      Abstract: The co-infection between visceral leishmaniasis (VL) and human immunodeficiency virus (HIV) has increased in several countries in the world. The current serological tests are not suitable since they present low sensitivity to detect the most of VL/HIV cases, and a more precise diagnosis should be performed. In this context, in the present study, an immunoproteomics approach was performed using Leishmania infantum antigenic extracts and VL, HIV and VL/HIV patients sera, besides healthy subjects samples; aiming to identify antigenic markers for these clinical conditions. Results showed that 43 spots were recognized by antibodies in VL and VL/HIV sera, and 26 proteins were identified by mass spectrometry. Between them, β-tubulin was expressed, purified and tested in ELISA experiments as a proof of concept for validation of our immunoproteomics findings and results showed high sensitivity and specificity values to detect VL and VL/HIV patients. In conclusion, the identified proteins in the present work could be considered as candidates for future studies aiming to improvement of the diagnosis of VL and VL/HIV co-infection.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000578
      Issue No: Vol. 147, No. 9 (2020)
  • Toxoplasma+gondii+ROP18+with+strain-specific+reactivity&rft.title=Parasitology&rft.issn=0031-1820&,+Chengjian+Han,+Yang+Wang,+Jingyang+Li,+Jinjin+Zhu,+Qingli+Luo,+Lingzhi+Chen,+Junling+Zhang,+Xiaojuan+Ding,+Jian+Du,+Deyong+Chu,+Yihong+Cai,+Jilong+Shen,+Li+Yu&rft_id=info:doi/10.1017/S0031182020000177">Production and characterization of monoclonal antibodies against
           Toxoplasma gondii ROP18 with strain-specific reactivity
    • Authors: Famin Zhang; Rui Su, Chengjian Han, Yang Wang, Jingyang Li, Jinjin Zhu, Qingli Luo, Lingzhi Chen, Junling Zhang, Xiaojuan Ding, Jian Du, Deyong Chu, Yihong Cai, Jilong Shen, Li Yu
      Pages: 940 - 948
      Abstract: The rhoptry kinase 18 of Toxoplasma gondii (TgROP18) has been identified as a key virulence factor that allows the parasite to escape from host immune defences and promotes its proliferation in host cells. Although much research is focused on the interaction between host cells and TgROP18, the development of monoclonal antibodies (mAbs) against TgROP18 has not been reported till date. To produce mAbs targeting TgROP18, two hybridomas secreting mAbs against TgROP18, designated as A1 and T2, were generated using cell fusion technology. The subtypes of the A1 and T2 mAbs were identified as IgG3 λ and IgM κ, and peptide scanning revealed that the core sequences of the antigenic epitopes were 180LRAQRRRSELVFE192 and 351NYFLLMMRAEADM363, respectively. The T2 mAb specifically reacted with both T. gondii type I and Chinese I, but not with T. gondii type II, Plasmodium falciparum or Schistosoma japonicum. Finally, the sequences of heavy chain and light chain complementarity-determining regions of T2 were amplified, cloned and characterized, making the modification of the mAb feasible in the future. The development of mAbs against TgROP18 would aid the investigation of the molecular mechanisms underlying the modulation of host cellular functions by TgROP18, and in the development of strategies to diagnose and treat Toxoplasmosis.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000177
      Issue No: Vol. 147, No. 9 (2020)
  • Echinococcus+granulosus+sensu+stricto,+Echinococcus+ortleppi;+and+E.+intermedius+(G7)+are+present+in+Bolivia&rft.title=Parasitology&rft.issn=0031-1820&,+P.+Duran,+M.+A.+Seláez,+M.+Barragan,+P.+Nogales,+A.+Peña+y+Lillo,+M.+Castañares,+Y.+Claros,+P.+Deplazes,+C.+A.+Alvarez+Rojas&rft_id=info:doi/10.1017/S0031182020000529">Echinococcus granulosus sensu stricto, Echinococcus ortleppi; and E.
           intermedius (G7) are present in Bolivia
    • Authors: V. Ali; E. Martinez, P. Duran, M. A. Seláez, M. Barragan, P. Nogales, A. Peña y Lillo, M. Castañares, Y. Claros, P. Deplazes, C. A. Alvarez Rojas
      Pages: 949 - 956
      Abstract: Cystic echinococcosis (CE) is a zoonotic disease caused by a complex of species known as Echinococcus granulosus sensu lato. CE is endemic in Argentina, Chile, Peru, Uruguay and the South part of Brazil. In contrast, little is known regarding the presence of CE in Bolivia. In this study, 35 cysts isolated from livestock (mostly from the Department of La Paz) and 3 from humans (La Paz, Oruro and Potosi) were genetically characterized analysing the sequence of the cox1 gene (1609 bp). In total, 30 cysts (from La Paz, Cochabamba and Beni) were characterized as E. granulosus sensu stricto (3 fertile and 4 non-fertile cysts from sheep, 8 fertile and 12 non-fertile cysts from cattle and 3 fertile cysts from humans). A detailed analysis of the cox1 haplotypes of E. granulosus s.s. is included. Echinococcus ortleppi (G5) was found in 5 fertile cysts from cattle (from La Paz and Cochabamba). Echinococcus intermedius (G7) was identified in 3 fertile cysts from pigs (from Santa Cruz). Additionally, E. granulosus s.s. was detected in 4 dog faecal samples, while E. ortleppi was present in other two dog faecal samples. The implications of these preliminary results in the future implementation of control measures are discussed.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000529
      Issue No: Vol. 147, No. 9 (2020)
  • Paramecium&rft.title=Parasitology&rft.issn=0031-1820&,+Natalia+Lebedeva,+Olivia+Lanzoni,+Giulio+Petroni,+Alexey+Potekhin,+Elena+Sabaneyeva&rft_id=info:doi/10.1017/S0031182020000633">The first case of microsporidiosis in        class="italic">Paramecium
    • Authors: Yulia Yakovleva; Elena Nassonova, Natalia Lebedeva, Olivia Lanzoni, Giulio Petroni, Alexey Potekhin, Elena Sabaneyeva
      Pages: 957 - 971
      Abstract: A new microsporidian species, Globosporidium paramecii gen. nov., sp. nov., from Paramecium primaurelia is described on the basis of morphology, fine structure, and SSU rRNA gene sequence. This is the first case of microsporidiosis in Paramecium reported so far. All observed stages of the life cycle are monokaryotic. The parasites develop in the cytoplasm, at least some part of the population in endoplasmic reticulum and its derivates. Meronts divide by binary fission. Sporogonial plasmodium divides by rosette-like budding. Early sporoblasts demonstrate a well-developed exospore forming blister-like structures. Spores with distinctive spherical shape are dimorphic in size (3.7 ± 0.2 and 1.9 ± 0.2 μm). Both types of spores are characterized by a thin endospore, a short isofilar polar tube making one incomplete coil, a bipartite polaroplast, and a large posterior vacuole. Experimental infection was successful for 5 of 10 tested strains of the Paramecium aurelia species complex. All susceptible strains belong to closely related P. primaurelia and P. pentaurelia species. Phylogenetic analysis placed the new species in the Clade 4 of Microsporidia and revealed its close relationship to Euplotespora binucleata (a microsporidium from the ciliate Euplotes woodruffi), to Helmichia lacustris and Mrazekia macrocyclopis, microsporidia from aquatic invertebrates.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000633
      Issue No: Vol. 147, No. 9 (2020)
  • Intestinal parasites in rural communities in Nan Province, Thailand:
           changes in bacterial gut microbiota associated with minute intestinal
           fluke infection
    • Authors: Ajala Prommi; Pinidphon Prombutara, Dorn Watthanakulpanich, Poom Adisakwattana, Teera Kusolsuk, Tippayarat Yoonuan, Akkarin Poodeepiyasawat, Nirundorn Homsuwan, Samreong Prummongkol, Malee Tanita, Sungkhom Rattanapikul, Chuanphot Thinphovong, Anamika Kritiyakan, Serge Morand, Kittipong Chaisiri
      Pages: 972 - 984
      Abstract: Gastrointestinal helminth infection likely affects the gut microbiome, in turn affecting host health. To investigate the effect of intestinal parasite status on the gut microbiome, parasitic infection surveys were conducted in communities in Nan Province, Thailand. In total, 1047 participants submitted stool samples for intestinal parasite examination, and 391 parasite-positive cases were identified, equating to an infection prevalence of 37.3%. Intestinal protozoan species were less prevalent (4.6%) than helminth species. The most prevalent parasite was the minute intestinal fluke Haplorchis taichui (35.9%). Amplicon sequencing of 16S rRNA was conducted to investigate the gut microbiome profiles of H. taichui-infected participants compared with those of parasite-free participants. Prevotella copri was the dominant bacterial operational taxonomic unit (OTU) in the study population. The relative abundance of three bacterial taxa, Ruminococcus, Roseburia faecis and Veillonella parvula, was significantly increased in the H. taichui-infected group. Parasite-negative group had higher bacterial diversity (α diversity) than the H. taichui-positive group. In addition, a significant difference in bacterial community composition (β diversity) was found between the two groups. The results suggest that H. taichui infection impacts the gut microbiome profile by reducing bacterial diversity and altering bacterial community structure in the gastrointestinal tract.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000736
      Issue No: Vol. 147, No. 9 (2020)
  • Plasmodium+cathemerium+(lineage+PADOM02)+from+the+sparrow+Passer+domesticus+with+complete+sporogony+in+Culex+pipiens+complex&rft.title=Parasitology&rft.issn=0031-1820&,+Salwa+I.+Sebak,+Ralph+E.+T.+Vanstreels,+Azza+M.+El+gendy&rft_id=info:doi/10.1017/S0031182020000566">Morphological and molecular characterization of Plasmodium cathemerium
           (lineage PADOM02) from the sparrow Passer domesticus with complete
           sporogony in Culex pipiens complex
    • Authors: Mohamed Z. Y. Aly; Ibrahem I. I. Mohamed, Salwa I. Sebak, Ralph E. T. Vanstreels, Azza M. El gendy
      Pages: 985 - 993
      Abstract: Avian malaria is a mosquito-borne disease caused by Plasmodium spp. protozoa. Although these parasites have been extensively studied in North America and Eurasia, knowledge on the diversity of Plasmodium, its vectors and avian hosts in Africa is scarce. In this study, we report on natural malarial infections in free-ranging sparrows (Passer domesticus) sampled at Giza Governorate, Egypt. Parasites were morphologically characterized as Plasmodium cathemerium based on the examination of thin blood smears from the avian host. Sequencing a fragment of the mitochondrial cytochrome b gene showed that the parasite corresponded to lineage PADOM02. Phylogenetic analysis showed that this parasite is closely related to the lineages SERAU01 and PADOM09, both of which are attributed to P. cathemerium. Experimental infection of Culex pipiens complex was successful, with ookinetes first detected at 1-day post infection (dpi), oocysts at 4 dpi and sporozoites at 6 dpi. The massive infection of the salivary glands by sporozoites corroborates that Cx. pipiens complex is a competent vector of PADOM02. Our findings confirm that Plasmodium lineage PADOM02 infects sparrows in urban areas along the Nile River, Egypt, and corroborate that Cx. pipiens complex is a highly competent vector for these parasites. Furthermore, our results demonstrate that this lineage corresponds to the morphospecies P. cathemerium and not P. relictum as previously believed.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000566
      Issue No: Vol. 147, No. 9 (2020)
  • ++memory+B+cells+induced+in+response+to+Plasmodium+berghei+adopt+a+germinal+centre+B+cell+phenotype+during+secondary+infection&rft.title=Parasitology&rft.issn=0031-1820&,+Diana+S.+Hansen&rft_id=info:doi/10.1017/S003118202000061X">IgM+ memory B cells induced in response to Plasmodium berghei adopt a
           germinal centre B cell phenotype during secondary infection
    • Authors: Halina M. Pietrzak; Lisa J. Ioannidis, Diana S. Hansen
      Pages: 994 - 998
      Abstract: Emerging evidence started to delineate multiple layers of memory B cells, with distinct effector functions during recall responses. Whereas most studies examining long-lived memory B cell responses have focussed on the IgG+ memory B cell compartment, IgM+ memory B cells have only recently started to receive attention. It has been proposed that unlike IgG+ memory B cells, which differentiate into antibody-secreting plasma cells upon antigen re-encounter, IgM+ memory B cells might have the additional capacity to establish secondary germinal centre (GC) responses. The precise function of IgM+ memory B cells in the humoral immune response to malaria has not been fully defined. Using a murine model of severe malaria infection and adoptive transfer strategies we found that IgM+ memory B cells induced in responses to P. berghei ANKA readily proliferate upon re-infection and adopt a GC B cell-like phenotype. The results suggest that that IgM+ memory B cells might play an important role in populating secondary GCs after re-infection with Plasmodium, thereby initiating the induction of B cell clones with enhanced affinity for antigen, at faster rates than naive B cells.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S003118202000061X
      Issue No: Vol. 147, No. 9 (2020)
  • Health policy impacts on malaria transmission in Costa Rica
    • Authors: Luis Fernando Chaves; Melissa Ramírez Rojas, Monica Prado, José Luis Garcés, Daniel Salas Peraza, Rodrigo Marín Rodríguez
      Pages: 999 - 1007
      Abstract: Costa Rica is near malaria elimination. This achievement has followed shifts in malaria health policy. Here, we evaluate the impacts that different health policies have had on malaria transmission in Costa Rica from 1913 to 2018. We identified regime shifts and used regression models to measure the impact of different health policies on malaria transmission in Costa Rica using annual case records. We found that vector control and prophylactic treatments were associated with a 50% malaria case reduction in 1929–1931 compared with 1913–1928. DDT introduction in 1946 was associated with an increase in annual malaria case reduction from 7.6% (1942–1946) to 26.4% (1947–1952). The 2006 introduction of 7-day supervised chloroquine and primaquine treatments was the most effective health policy between 1957 and 2018, reducing annual malaria cases by 98% (2009–2018) when compared with 1957–1968. We also found that effective malaria reduction policies have been sensitive to natural catastrophes and extreme climatic events, both of which have increased malaria transmission in Costa Rica. Currently, outbreaks follow malaria importation into vulnerable areas of Costa Rica. This highlights the need to timely diagnose and treat malaria, while improving living standards, in the affected areas.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000621
      Issue No: Vol. 147, No. 9 (2020)
  • Giardia+lamblia+strains:+investigation+of+antigenic+variation+in+the+post-genomic+era&rft.title=Parasitology&rft.issn=0031-1820&üller&rft.aufirst=Joachim&üller&,+Anne-Christine+Uldry,+Manfred+Heller,+Norbert+Müller&rft_id=info:doi/10.1017/S0031182020000657">Comparative proteomics of three Giardia lamblia strains: investigation of
           antigenic variation in the post-genomic era
    • Authors: Joachim Müller; Sophie Braga, Anne-Christine Uldry, Manfred Heller, Norbert Müller
      Pages: 1008 - 1018
      Abstract: Giardia lamblia is a causative agent of persistent diarrhoea widespread in regions with low hygienic standards. Laboratory research is based on cloned lines issuing from various patient isolates typed in the late 1980s and 90s using restriction analysis and serology. In the present study, we compared the well-characterized strain WBC6 with another clone of the parent WB isolate termed WBA1 and with a clone from another isolate, GS/M-83-H7, using shotgun mass spectrometry proteomics. We identified 398 proteins differentially expressed between the GS and both WB isolates and 97 proteins differentially expressed between the two WB isolates. We investigated the expression levels of the predominant variant-specific surface proteins (VSPs) in each clone and matched the previously described major VSPs of each strain to the corresponding open reading frame sequences identified by whole-genome sequencing efforts. Furthermore, since the original WB isolate comes from a patient treated with metronidazole, we compared the susceptibilities of the strains to nitro compounds, as well the expression levels of enzymes involved in nitro reduction and on the corresponding enzyme activities and found distinct differences between the three strains.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000657
      Issue No: Vol. 147, No. 9 (2020)
  • Vairimorpha+leptinotarsae+comb.+nov.+on+the+basis+of+molecular+characterization+of+Nosema+leptinotarsae+Lipa,+1968+(Microsporidia:+Nosematidae)&rft.title=Parasitology&rft.issn=0031-1820&Çağrı&Çağrı+Bekircan&rft_id=info:doi/10.1017/S0031182020000669">Assignment of Vairimorpha leptinotarsae comb. nov. on the basis of
           molecular characterization of Nosema leptinotarsae Lipa, 1968
           (Microsporidia: Nosematidae)
    • Authors: Çağrı Bekircan
      Pages: 1019 - 1025
      Abstract: Nosema leptinotarsae Lipa, 1968 is a microsporidian pathogen of the Colorado potato beetle, Leptinotarsa decemlineata Say. (Coleoptera: Chrysomelidae). To determine the phylogenetic status of N. leptinotarsae, the 16S SSU rRNA gene was sequenced (GenBank Accession No. MN841279) and compared phylogenetically against 21 microsporidian 16S SSU rRNA sequences using neighbour-joining and maximum-parsimony methods. The per cent identities of the N. leptinotarsae and other members of the Nosema–Vairimorpha clade ranged from 78.1 to 98.5%. Pairwise phylogenetic distances between the N. leptinotarsae and other species ranged from 0.009 to 0.320. Phylogenetic analysis shows clearly that N. leptinotarsae is a member of the Vairimorpha clade rather than the Nosema clade. The sequence divergence and morphological traits separated the N. leptinotarsae from other species in the Vairimorpha complex. As a result, a new assignment of Vairimorpha leptinotarsae comb. nov. has been implemented for N. leptinotarsae according to the phylogenetical positioning in the present study.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000669
      Issue No: Vol. 147, No. 9 (2020)
  • Albendazole solid dispersions against alveolar echinococcosis: a
           pharmacotechnical strategy to improve the efficacy of the drug
    • Authors: Julia Fabbri; Patricia Eugenia Pensel, Clara María Albani, Lurdes Milagros Lopez, Analia Simonazzi, José María Bermudez, Santiago Daniel Palma, María Celina Elissondo
      Pages: 1026 - 1031
      Abstract: Alveolar echinococcosis is a neglected parasitic zoonosis caused by Echinococcus multilocularis. The pharmacological treatment is based on albendazole (ABZ). However, the low water solubility of the drug produces a limited dissolution rate, with the consequent failure in the treatment of the disease. Solid dispersions are a successful pharmacotechnical strategy to improve the dissolution profile of poorly water-soluble drugs. The aim of this work was to determine the in vivo efficacy of ABZ solid dispersions using poloxamer 407 as a carrier (ABZ:P407 solid dispersions (SDs)) in the murine intraperitoneal infection model for secondary alveolar echinococcosis. In the chemoprophylactic efficacy study, the ABZ suspension, the ABZ:P407 SDs and the physical mixture of ABZ and poloxamer 407 showed a tendency to decrease the development of murine cysts, causing damage to the germinal layer. In the clinical efficacy study, the ABZ:P407 SDs produced a significant decrease in the weight of murine cysts. In addition, the SDs produced extensive damage to the germinal layer. The increase in the efficacy of ABZ could be due to the improvement of water solubility and wettability of the drug due to the surfactant nature of poloxamer 407. In conclusion, this study is the basis for further research. This pharmacotechnical strategy might in the future offer novel treatment alternatives for human alveolar echinococcosis.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000670
      Issue No: Vol. 147, No. 9 (2020)
  • Single-dose treatment for cutaneous leishmaniasis with an easily
           synthesized chalcone entrapped in polymeric microparticles
    • Authors: Ariane J. Sousa-Batista; Natalia Arruda-Costa, Douglas O. Escrivani, Franceline Reynaud, Patrick G. Steel, Bartira Rossi-Bergmann
      Pages: 1032 - 1037
      Abstract: Cutaneous leishmaniasis (CL) is a major health problem in many countries and its current treatment involves multiple parenteral injections with toxic drugs and requires intensive health services. Previously, the efficacy of a single subcutaneous injection with a slow-release formulation consisting of poly(lactide-co-glycolide) (PLGA) microparticles loaded with an antileishmanial 3-nitro-2-hydroxy-4,6-dimethoxychalcone (CH8) was demonstrated in mice model. In the search for more easily synthesized active chalcone derivatives, and improved microparticle loading, CH8 analogues were synthesized and tested for antileishmanial activity in vitro and in vivo. The 3-nitro-2′,4′,6′-trimethoxychalcone (NAT22) analogue was chosen for its higher selectivity against intracellular amastigotes (selectivity index = 1489, as compared with 317 for CH8) and more efficient synthesis (89% yield, as compared with 18% for CH8). NAT22 was loaded into PLGA / polyvinylpyrrolidone (PVP) polymeric blend microspheres (NAT22-PLGAk) with average diameter of 1.9 μm. Although NAT22-PLGAk showed similar activity to free NAT22 in killing intracellular parasites in vitro (IC50 ~ 0.2 μm), in vivo studies in Leishmania amazonensis – infected mice demonstrated the significant superior efficacy of NAT22-PLGAk to reduce the parasite load. A single intralesional injection with NAT22-PLGAk was more effective than eight injections with free NAT22. Together, these results show that NAT22-PLGAk is a promising alternative for single-dose localized treatment of CL.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000712
      Issue No: Vol. 147, No. 9 (2020)
  • The diversity and distribution of chigger mites associated with rodents in
           the South African savanna
    • Authors: Sonja Matthee; Alexandr A. Stekolnikov, Luther van der Mescht, Götz Froeschke, Serge Morand
      Pages: 1038 - 1047
      Abstract: Chigger mites (Trombiculidae) are temporary habitat-specific ectoparasites that often occur on rodents. Little ecological data are available on chiggers associated with rodents in South Africa. The study aims were to (1) record the chigger species associated with rodents in the savanna, (2) assess if chigger species display parasitope preference on the rodent body and (3) compare the distribution of chigger species in natural, agricultural and urban habitats. Rodents (n = 314) belonging to eight genera were trapped in the savanna biome during 2014 and 2015. Twelve chigger species, of which five are recently described species, were recorded from 161 rodent hosts. The data include three new country locality records. Microtrombicula mastomyia was the most prevalent species across sampling seasons and habitat types. Significant parasitope preference was recorded for two species, with the ear, face and tail base some of the preferred attachment sites. Sampling season and habitat type had a significant effect on chigger communities with summer and agricultural habitats recording the highest species richness, while the highest species diversity was recorded in natural habitats. The study contributes to our current knowledge regarding rodent-associated chigger diversity and distribution in South Africa and further highlights the importance of environmental characteristics in shaping chigger communities.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000748
      Issue No: Vol. 147, No. 9 (2020)
  • Echinococcus+multilocularis+metacestodes&rft.title=Parasitology&rft.issn=0031-1820&äe&rft.aufirst=Teivi&äe&,+Cristian+A.+Alvarez+Rojas,+Theodor+W.+Ramp,+Johannes+Eckert,+Peter+Deplazes&rft_id=info:doi/10.1017/S003118202000075X">Long-term (35 years) cryopreservation of Echinococcus multilocularis
    • Authors: Teivi Laurimäe; Philipp A. Kronenberg, Cristian A. Alvarez Rojas, Theodor W. Ramp, Johannes Eckert, Peter Deplazes
      Pages: 1048 - 1054
      Abstract: The metacestode of Echinococcus multilocularis is the etiological agent of alveolar echinococcosis. The metacestode stage used for research is maintained in rodents by serial passages. In order to determine whether cryopreservation of E. multilocularis metacestodes would be suitable for long-term maintenance and replace serial passages, isolates of different geographic origin were cryopreserved in 1984–1986. The aim of the current study was to test the viability of cryopreserved isolates following long-term cryopreservation (up to 35 years) and to determine the phylogenetic clades these isolates belonged to. Cryopreserved isolates were tested for viability in vitro and in vivo in gerbils. In vitro results of 5 isolates indicated protoscolex survival in 13 of 17 experiments (76%) and metacestode survival in 5 of 12 (42%) in vivo experiments. In vivo results showed ‘abortive lesions’ in 13 of the 36 animals, 15 were negative and 8 harboured proliferating metacestode tissue containing protoscoleces. Genetic analysis confirmed the isolates belonged to European, Asian and North-American clades. In conclusion, the results of the current study indicate that metacestodes of E. multilocularis are able to survive long-term cryopreservation. Therefore, cryopreservation is a suitable method for long-term storage of E. multilocularis metacestode isolates and reduces the number of experimental animals.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S003118202000075X
      Issue No: Vol. 147, No. 9 (2020)
  • Echinococcus+canadensis+(G6/G7)+in+sheep+in+Turkey&rft.title=Parasitology&rft.issn=0031-1820&,+Figen+Celik,+Harun+Kaya+Kesik,+Seyma+Gunyakti+Kilinc,+Haroon+Ahmed&rft_id=info:doi/10.1017/S0031182020000785">Molecular survey on cattle and sheep hydatidosis and first detection of
           Echinococcus canadensis (G6/G7) in sheep in Turkey
    • Authors: Sarfraz Mehmood; Sami Simsek, Figen Celik, Harun Kaya Kesik, Seyma Gunyakti Kilinc, Haroon Ahmed
      Pages: 1055 - 1062
      Abstract: Larval stage of genus Echinococcus is the causing agent for the zoonotic infection which is life threatening known as Echinococcosis. The purpose of this study was the identification, molecular analysis and characterization of Echinococcus spp. in sheep and cattle. The sampling was done from slaughterhouse of Elazig, Turkey. A total of 85 isolates (sheep, n = 19 and cattle, n = 66) have been collected after slaughtering. Following the gDNA isolation and PCR products of mt-CO1 gene (446 bp) of all the samples were sequenced. Out of 85 isolates, 84 were recognized as Echinococcus granulosus sensu stricto and one sheep isolate was found as Echinococcus canadensis (G6/G7 ) which is identified for the first time in Turkey. However, single nucleotide polymorphism has been observed not only in samples of different animals but also in samples collected from the same cattle. Six liver and three lung hydatid cysts have been detected in cattle. Although no nucleotide differences have been observed in the liver samples, there was single nucleotide polymorphism (C→T) in 40th nucleotide of two lung cysts. As a result of haplotype analysis, 16 haplotypes of E. granulosus s.s. were detected in 66 cattle isolates whereas 7 haplotypes of E. granulosus s.s. were identified in 19 sheep samples.
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000785
      Issue No: Vol. 147, No. 9 (2020)
  • Black sea bass are a host in the developmental cycle of Lernaeenicus
           radiatus (Copepoda: Pennellidae): insights into parasite morphology, gill
           pathology and genetics – CORRIGENDUM
    • Authors: J. Lovy; S. E. Friend
      Pages: 1063 - 1063
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000694
      Issue No: Vol. 147, No. 9 (2020)
  • 1H+NMR+spectroscopy+–+CORRIGENDUM&rft.title=Parasitology&rft.issn=0031-1820&,+Fateme+Hajialiani,+Manijeh+Motevalian,+Maryam+Mohamadi,+Sedigheh+Sadeghi,+Zahra+Zamani,+Fatemeh+Tabatabaie&rft_id=info:doi/10.1017/S0031182020000682">Novel chloroquine loaded curcumin based anionic linear globular dendrimer
           G2: a metabolomics study on Plasmodium falciparum in vitro using 1H NMR
           spectroscopy – CORRIGENDUM
    • Authors: Taher Elmi; Mehdi Shafiee Ardestani, Fateme Hajialiani, Manijeh Motevalian, Maryam Mohamadi, Sedigheh Sadeghi, Zahra Zamani, Fatemeh Tabatabaie
      Pages: 1064 - 1064
      PubDate: 2020-08-01T00:00:00.000Z
      DOI: 10.1017/S0031182020000682
      Issue No: Vol. 147, No. 9 (2020)
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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