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American Journal of Microbiological Research
Number of Followers: 4

This is an Open Access Journal

Open Access journal
ISSN (Print) 2328-4129 - ISSN (Online) 2328-4137
Published by Science and Education Publishing

[75 journals]

Stenotrophomonas maltophilia an Emerging Opportunistic Bacterial Infection
Isolated from Diverse Clinical Samples
- Authors: Puneeta Singh; Shalabh Malik, Vandana Lal
  Pages: 50 - 54
  Abstract: Aim: The aim of this study was to assess the prevalence of infection, antimicrobial susceptibility pattern of Stenotrophomonas maltophilia in diverse samples in the Delhi. Materials and Methods: This is a retrospective study conducted over a period of three years, i.e., January 2019 to December 2021. All clinical samples received in the microbiology laboratory at Dr Lal Path Labs, Delhi during the study period were processed using standard microbiological procedures. Antibiotic susceptibility was performed for Levofloxacin, Minocycline and Trimethoprim-sulfamethoxazole by Vitek 2 system (bioMerieux, India) as per CLSI guidelines. Results and Discussion: A total of 9615 non fermenters were isolated, among the non-fermenters, 375 (3.9%) were Stenotrophomonas maltophilia. The most prevalent source of S. maltophilia was largely isolated from blood (34.7%) followed by fluids (20.3%), respiratory (17.8%) and other specimens. This study highlighted potency and the limitation of available agent in the era of antibiotic resistance especially in Delhi, India. Our study describes the distribution and antibiotic resistance of Levofloxacin, Trimethoprim-sulfamethoxazole and Minocycline based on cumulative interpretation and MIC across all age groups. Conclusion: The Stenotrophomonas maltophilia isolates collected in our study had relatively high susceptibility to Minocycline, good susceptibility to Trimethoprim/sulfamethoxazole, but low susceptible to Levofloxacin. Minocycline, could be useful alternative treatment options in Trimethoprim/sulfamethoxazole and Levofloxacin resistant strains.
  PubDate: 2022-06-06
  Issue No: Vol. 10, No. 2 (2022)
Emergence of Monkeypox Raises a Serious Challenge to Public Health
- Authors: Mahendra Pal; Kirubel Paulos Gutama
  Pages: 55 - 58
  Abstract: Monkeypox is an emerging and re-emerging viral zoonotic disease caused by the Monkeypox virus, which is considered the most important Orthopoxvirus infection since smallpox eradication. Although most cases are documented in Central and West Africa, there have been sporadic cases reported all across the world, sometimes involving travelers. Outside of Africa, the current outbreak is the largest ever. Close personal contact is how Monkeypox virus spreads. The most prevalent routes of infection for humans include respiratory, percutaneous, and permucosal exposures to infected monkeys, zoo animals, prairie dogs, and people. Flu-like symptoms (fever, fatigue, and muscular aches), swollen lymph nodes, and a rash are all commonly observed in monkeypox. The rash can develop anywhere on the body, including the face, genitals, palms, and soles of the feet. The prognosis of the disease in immunocompromised patients is poor. The techniques for the diagnosis of the disease include laboratory culture, polymerase chain reaction (PCR), immunohistochemistry, and electron microscopy. Antiviral drugs such as tecovirimat, cidofovir, and brincidofovir, which are used to treat smallpox, can also be used for monkeypox. Ring vaccination, or targeted smallpox immunization for close contacts of an infected individual, can be used to reduce monkeypox. JYNNEOS is a non-replicating smallpox and monkeypox vaccination that is newer and safer. Other monkeypox vaccines, such as VAC6 and LC16.20, are in the development stage.
  PubDate: 2022-06-29
  Issue No: Vol. 10, No. 2 (2022)

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