Publisher: Science and Education Publishing   (Total: 75 journals)   [Sort by number of followers]

Showing 1 - 75 of 75 Journals sorted alphabetically
American J. of Applied Mathematics and Statistics     Open Access   (Followers: 15)
American J. of Applied Psychology     Open Access   (Followers: 58)
American J. of Biomedical Research     Open Access   (Followers: 4)
American J. of Cancer Prevention     Open Access   (Followers: 14)
American J. of Civil Engineering and Architecture     Open Access   (Followers: 49)
American J. of Clinical Medicine Research     Open Access   (Followers: 8)
American J. of Educational Research     Open Access   (Followers: 75)
American J. of Electrical and Electronic Engineering     Open Access   (Followers: 29)
American J. of Energy Research     Open Access   (Followers: 11)
American J. of Environmental Protection     Open Access   (Followers: 9)
American J. of Epidemiology and Infectious Disease     Open Access   (Followers: 22)
American J. of Food and Nutrition     Open Access   (Followers: 66)
American J. of Food Science and Technology     Open Access   (Followers: 13)
American J. of Infectious Diseases and Microbiology     Open Access   (Followers: 32)
American J. of Information Systems     Open Access   (Followers: 7)
American J. of Materials Engineering and Technology     Open Access   (Followers: 6)
American J. of Materials Science and Engineering     Open Access   (Followers: 8)
American J. of Mathematical Analysis     Open Access   (Followers: 2)
American J. of Mechanical Engineering     Open Access   (Followers: 61)
American J. of Medical and Biological Research     Open Access   (Followers: 11)
American J. of Medical Case Reports     Open Access   (Followers: 3)
American J. of Medical Sciences and Medicine     Open Access   (Followers: 6)
American J. of Medicine Studies     Open Access   (Followers: 3)
American J. of Microbiological Research     Open Access   (Followers: 3)
American J. of Modeling and Optimization     Open Access   (Followers: 3)
American J. of Nanomaterials     Open Access   (Followers: 7)
American J. of Numerical Analysis     Open Access   (Followers: 3)
American J. of Nursing Research     Open Access   (Followers: 12)
American J. of Pharmacological Sciences     Open Access   (Followers: 2)
American J. of Public Health Research     Open Access   (Followers: 30)
American J. of Rural Development     Open Access   (Followers: 9)
American J. of Sensor Technology     Open Access   (Followers: 4)
American J. of Sports Science and Medicine     Open Access   (Followers: 39)
American J. of Water Resources     Open Access   (Followers: 16)
American J. of Zoological Research     Open Access   (Followers: 3)
Applied Ecology and Environmental Sciences     Open Access   (Followers: 28)
Applied Mathematics and Physics     Open Access   (Followers: 4)
Automatic Control and Information Sciences     Open Access   (Followers: 3)
Biomedical Science and Engineering     Open Access   (Followers: 7)
Chemical Engineering and Science     Open Access   (Followers: 48)
Intl. J. of Celiac Disease     Open Access   (Followers: 3)
Intl. J. of Dental Sciences and Research     Open Access   (Followers: 1)
Intl. J. of Econometrics and Financial Management     Open Access   (Followers: 7)
Intl. J. of Physics     Open Access   (Followers: 12)
Intl. Transaction of Electrical and Computer Engineers System     Open Access   (Followers: 2)
J. of Automation and Control     Open Access   (Followers: 10)
J. of Biomedical Engineering and Technology     Open Access   (Followers: 1)
J. of Business and Management Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Treatment     Open Access   (Followers: 4)
J. of Computer Networks     Open Access   (Followers: 8)
J. of Computer Sciences and Applications     Open Access  
J. of Environment Pollution and Human Health     Open Access   (Followers: 9)
J. of Finance and Accounting     Open Access   (Followers: 9)
J. of Finance and Economics     Open Access   (Followers: 13)
J. of Food and Nutrition Research     Open Access   (Followers: 12)
J. of Food Security     Open Access   (Followers: 10)
J. of Geosciences and Geomatics     Open Access   (Followers: 2)
J. of Materials Physics and Chemistry     Open Access   (Followers: 6)
J. of Mathematical Sciences and Applications     Open Access   (Followers: 3)
J. of Optoelectronics Engineering     Open Access   (Followers: 4)
J. of Physical Activity Research     Open Access   (Followers: 5)
J. of Polymer and Biopolymer Physics Chemistry     Open Access   (Followers: 10)
Materials Science and Metallurgy Engineering     Open Access   (Followers: 7)
Nanoscience and Nanotechnology Research     Open Access   (Followers: 20)
Physics and Materials Chemistry     Open Access   (Followers: 2)
Research in Plant Sciences     Open Access   (Followers: 2)
Research in Psychology and Behavioral Sciences     Open Access   (Followers: 4)
Sustainable Energy     Open Access   (Followers: 3)
Turkish J. of Analysis and Number Theory     Open Access   (Followers: 1)
Wireless and Mobile Technologies     Open Access   (Followers: 5)
World J. of Agricultural Research     Open Access   (Followers: 3)
World J. of Analytical Chemistry     Open Access   (Followers: 4)
World J. of Chemical Education     Open Access   (Followers: 6)
World J. of Environmental Engineering     Open Access   (Followers: 3)
World J. of Organic Chemistry     Open Access   (Followers: 8)
Similar Journals
Journal Cover
American Journal of Cancer Prevention
Number of Followers: 14  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2328-7322 - ISSN (Online) 2328-7314
Published by Science and Education Publishing Homepage  [75 journals]
  • Hematological and Biochemical Changes in Patients with Multiple Myeloma
           Treated with Bortezomib Based Triple Drug Combination Chemotherapy

    • Authors: Mahbuba Sharmin; Amin Lutful Kabir, Naseeb Muhammad. Irshadullah, Mohammad Shahidul Alam, A S M Anwarul Kabir, Abdul Aziz, Hafizur Rahman
      Pages: 1 - 6
      Abstract: Background: Multiple Myeloma (MM) is a neoplastic clonal disorder and accounts for 1% of malignant tumors and 10%–15% of hematopoietic neoplasms. The prognosis of Multiple Myeloma has reversed by the advent of novel agents and triple combination therapy (Bortezomib, Thalidomide, Dexamethasone) that serve the basis of future strands of care in Multiple Myeloma patients. Objective: The aim of the study was to assess the safety, efficacy and tolerability of Bortezomib in newly diagnosed cases of Multiple Myeloma patients in Bangladesh. Materials &Methods: We undertook this clinicopathological study to assess the profile of Multiple Myeloma patients, evaluate hematological and biochemical response of 36 newly diagnosed cases of MM with or without renal impairment receiving 4 cycles of Bortezomib, Thalidomide and Dexamethasone (BTD). Results: Among the study population, 36(100%) patients had weakness. followed by anaemia (97%), bone pain (89%) and renal impairment (44%). During treatment, 8 patients (22%) suffered from somnolence, 5 patients (14%) had Peripheral neuropathy and 6 (17%) patients complained of constipation. We found 8% suffered from hyperglycaemia, 3% rash, 3% cardiac arrest, 6% electrolyte imbalance and life threatening intracranial haemorrhage occurred in 1 patient (3%). Out of 36 patients, complete response achieved in 18 patients (50%), where 6 patients (16%) showed partial response, 10 (28%) showed very good partial response and 2 (6%) patients showed no response. The overall response rate was 94% belonged to complete response(CR), Partial response(PR),very good partial response(VGPR). Conclusion: Bortezomib based combination therapy is a highly effective and safe regimen for newly diagnosed Multiple Myeloma patients. . It can be administered safely in the outpatient setting provided by clinicians.
      PubDate: 2020-07-02
      DOI: 10.12691/ajcp-8-1-1
      Issue No: Vol. 8, No. 1 (2020)
       
  • Histone Acetylation Modification H4K16ac Involved in Notch1 Signaling in
           Breast Cancer

    • Authors: Ya-qi Wang; Jing-hua Zhang, Zhao-yuan Wan, Dan Li
      Pages: 7 - 12
      Abstract: The Notch signaling pathway is a fundamental intercellular signaling system that regulates cell fate decisions in terms of proliferation and differentiation in multiple tissues. Abnormal activation of Notch1 signaling pathway leads to a variety of diseases, including the malignant tumors. Dysregulated Notch receptor activity has been implicated in breast cancer but the epigenetic mechanisms remains not clear. Compared to adjacent tissues, high expression of NIC1 and low expression of H4K16ac were found in cancer tissues. Notch1 knocked down in the breast cancer cell line MCF-7 resulted in increased H4K16ac expression and a parallel reduction in their proliferation and migration capacity. Our study prompting H4K16ac to participate in the signal transduction of Notch1 in breast cancer cells. These results confirm Notch1 as a signal triggering epigenetic mechanisms in breast cancer cells, which may have implications in tumor dissemination, metastasis and proliferation. The identification of specific factors interacting with NOTCH signaling could thus be relevant to fully understanding the role of NOTCH in breast neoplasia.
      PubDate: 2020-12-11
      DOI: 10.12691/ajcp-8-1-2
      Issue No: Vol. 8, No. 1 (2020)
       
 
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