Publisher: Sjournals   (Total: 11 journals)   [Sort by number of followers]

Showing 1 - 11 of 11 Journals sorted alphabetically
Agricultural Advances     Open Access   (Followers: 4)
Health, Safety and Environment     Open Access   (Followers: 37)
Scientific J. of Animal Science     Open Access   (Followers: 5)
Scientific J. of Biological Sciences     Open Access   (Followers: 2)
Scientific J. of Crop Science     Open Access   (Followers: 2)
Scientific J. of Environmental Sciences     Open Access   (Followers: 1)
Scientific J. of Medical Science     Open Access  
Scientific J. of Pure and Applied Sciences     Open Access   (Followers: 2)
Scientific J. of Review     Open Access   (Followers: 1)
Scientific J. of Veterinary Advances     Open Access   (Followers: 1)
Scientific J. of Zoology     Open Access   (Followers: 6)
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Health, Safety and Environment
Number of Followers: 37  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2345-2838
Published by Sjournals Homepage  [11 journals]
  • Editorial

    • Authors: Seyed Shamseddin Alizadeh
      Abstract: Editor
      PubDate: Sat, 14 Nov 2020 00:00:00 +010
       
  • TOXICITY AND ANALGESIC STUDIES OF LEAF METHANOLIC EXTRACT OF MAYTENUS
           SENEGALENSIS (LAM.) EXELL (CELASTRACEAE)

    • Authors: A. A. Murjanatu; K. Y. Musa, G. Ibrahim, M. G. Magaji
      Abstract: The leaf methanolic extract of Maytenus senegalensis (Lam.) Exell was investigated for toxicity and analgesic effects. Acute toxicity was investigated via intraperitoneal route using mice and rats, analgesic activity was investigated using two models; acetic acid-induced writhing in mice and formalin induced pain in rats. The extract was determined to have LD (50) of 1264.91 mg/kg in both mice and rats. It significantly (0.001) inhibited acetic acid-induced writhes in mice at all doses administered (75, 150 and 300 mg/kg) in a dose dependent manner and significantly (0.01) inhibited formalin induced pain in rats, in a non-dose dependent manner. The inhibitory effect observed was higher in the extract compared to the standard used (piroxicam). The results obtained suggested the extract to be relatively toxic in both mice and rats with a dose dependent anti-nociceptive activity.
      PubDate: Fri, 13 Nov 2020 00:00:00 +010
       
 
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