Publisher: Academic Journals Inc   (Total: 4 journals)   [Sort alphabetically]

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American J. of Biochemistry and Molecular Biology     Open Access   (Followers: 24)
American J. of Drug Discovery and Development     Open Access   (Followers: 3)
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American Journal of Drug Discovery and Development
Number of Followers: 3  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2150-427x
Published by Academic Journals Inc Homepage  [4 journals]
  • Leptadenia hastata Pers. (Decne) a Promising Source for Natural Compounds
           in Biomedical Applications

    • Abstract: Leptadenia hastata (Pers) Decne. of Apocynaceae family is an African plant which is used as nutriment as well as for medical purposesdue to its health promoting properties. Traditional healers use L. hastata to treat many diseases as hypertension, sexual impotence,trypanosomosis, acute rhinopharyngitis. In quantitative and qualitative terms, the leaves of L. hastata contain significant quantities ofsecondary metabolites, as triterpenes, total flavonoids, tanins, which can be important in biomedical research. In vivo studies showedthe antifertility effect of L. hastata leaves extracts which can be useful for hormonal therapy replacement. Herein, the ecology, traditionalmedicinal uses, phytochemistry, toxicity and pharmacology of L. hastata in consideration of its antifertility activity is reviewed. In viewof its constituents such as steroidal glycosides, triterpenes and polyoxypregnane derivatives, further investigation on the effect ofL. hastata on other hormonal endpoints like hormone dependent cancers appears promising.
      PubDate: 13 December, 2018
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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