Publisher: Academic Journals Inc   (Total: 4 journals)   [Sort alphabetically]

Showing 1 - 4 of 4 Journals sorted by number of followers
American J. of Biochemistry and Molecular Biology     Open Access   (Followers: 24)
American J. of Drug Discovery and Development     Open Access   (Followers: 3)
European J. of Dentistry and Medicine     Open Access   (Followers: 3)
Bacteriology J.     Open Access   (Followers: 2)
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American Journal of Biochemistry and Molecular Biology
Number of Followers: 24  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2150-4210 - ISSN (Online) 2150-4253
Published by Academic Journals Inc Homepage  [4 journals]
  • Regulation of Connective Components in Indomethacin-induced Gastric Ulcer
           Healing in Wistar Rats

    • Abstract: Background and Objective: There are growing evidences that non-steroidal anti-inflammatory drugs (NSAIDs)-induced depression of mitochondrial functions and activation of collagenase by lesions in the stomach. Therefore, this study sought to investigate possible mechanism of action of oleic acid rich fraction of n-hexane extract of Chasmanthera dependens (OHECD) in indomethacin-induced gastric ulcer. Materials and Methods: Gastric ulcer was induced using indomethacin orally. Gastric ulceration was assessed and gastric ulcer healing were analyzed by assessing the ulcer score, ulcer index, percentage healing, mucus content and levels of proline, hydroxyproline, nitric oxide and activities of pepsin and citrate synthase in the serum and gastric tissues. Results: Indomethacin (IND) caused severe gastric mucosa damage with ulcer score and ulcer index of 3.75±0.20 and 2.62±0.37 relative to control group at p
      PubDate: 04 May, 2021
       
  • Levamisole Efficacy on the Helminths of Dog in National Veterinary
           Research Institute Vom (NVRI) Environment

    • Abstract: Background and Objectives: Levamisole is an anthelmintics drug principally use for the treatment and control the range of nematodes in animal and human. It is I-isomer of dI-tetramisole with greater safety margin than the racemic mixture tetramisole. This study was designed to examine the efficacy of levamisole by using modified Mc-master technique. Materials and Methods: The experiment was performed on 25 dogs in Vom environment using Modifying Mc-master chamber, polytene bag, concentrated salt solution, microscope, universal bottle and syringe and needle. There were 10 male and 15 female dogs, out of the 25 dogs sampled during the experiment. The organisms identified were Hookworm, Toxocara and Coccidia. The faecal samples were collected directly from both clinical and sub-clinical cases from the rectum labelled and taken to National Veterinary Research institute (NVRI), Vom, Nigeria, Parasitology laboratory for analysis to determine the presence of helminths, eggs and oocyst. The dogs were then treated with levamisole orally and re-sampled after 24 h and analyzed in the NVRI Parasitology laboratory. Results: Out of 25 dogs that were sampled 15 are positive while 10 are negative for helminthosis. The results were obtained by comparing the percentage reduction of worm’s burden of the first sample collected and the second sample collected after medication. The results were expressed in term of percentage reduction, but from the obtained result showed significant reduction between the first and second samples in hookworm, toxocara ova, but there is no significant reduction in coccidia organism. Conclusion: From the study it was reaffirmed that levamisole does not have any effect on the coccidian organism, but it has an anthelmintic property on nematodes such as; hookworms and toxocara organism with some level of resistant in some of the dogs.
      PubDate: 04 May, 2021
       
  • Evaluation of Anemia among Men and Women with Acute Renal Disease in Jos,
           Plateau State, Nigeria

    • Abstract: Background and Objective: Acute Renal Failure or disease (ARF) is a complicated disorder that causes a fast reduction in kidney function and anemia is a common feature of this disease. This study aimed to evaluate the anemia situation in patients with acute renal failure among men and women. Materials and Methods: This case study was conducted on 56 patients with acute renal failure attending DEE Medical Center, Buruku, Jos, Plateau State Nigeria, from January-September, 2019. Initially, two separate blood samples were taken from each patient, 2 mL uncoagulated sample harvest for biochemical assay and EDTA anticoagulated whole blood sample for hematocrit value. Serum was used to determine the level of urea, creatinine and hematocrit value was done with EDTA anticoagulated samples by hematocrit centrifuge. The values obtained in urea and creatinine were divided into three groups: low, moderate and high, data obtained were analyzed by SPSS software. Results: Generally, the study revealed the anemic condition of all the acute renal disease patients irrespective of gender (p
      PubDate: 04 May, 2021
       
 
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