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Publisher: Medknow Publishers   (Total: 355 journals)

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Showing 1 - 200 of 355 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access   (Followers: 2)
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 6)
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Ancient Science of Life     Open Access   (Followers: 5)
Anesthesia : Essays and Researches     Open Access   (Followers: 9)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 4)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 7, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 5, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 12, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 10)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Pharmacy Practice     Open Access   (Followers: 6)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 4)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Cancer Translational Medicine     Open Access   (Followers: 2)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 2)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 10, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 11)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 6, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access   (Followers: 1)
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access   (Followers: 1)
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access   (Followers: 2)
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 3)
European J. of Psychology and Educational Studies     Open Access   (Followers: 11)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 3, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (Followers: 1, SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 2, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 4, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 3, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 5, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 8, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 2, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 3, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 6)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 2)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 5, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 13)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 5)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 3)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 3, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 7, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access   (Followers: 1)
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 5, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (Followers: 1, SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access   (Followers: 1)
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 2)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 3)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 2)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 2)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 9, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access   (Followers: 2)
J. of Family Medicine and Primary Care     Open Access   (Followers: 11)

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Journal Cover Astrocyte
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 2349-0977 - ISSN (Online) 2349-4387
   Published by Medknow Publishers Homepage  [355 journals]
  • Kindling Trust, Instilling Faith: Open Sesame to a Healthy
           Doctor–Patient Relationship

    • Authors: Yatish Agarwal, Rashmikant Dave
      Pages: 135 - 138
      Abstract: Yatish Agarwal, Rashmikant Dave
      Astrocyte 2017 4(3):135-138

      Citation: Astrocyte 2017 4(3):135-138
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/2349-0977.224234
      Issue No: Vol. 4, No. 3 (2018)
       
  • Comparative Study on Prediction and Course of Significant
           Hyperbilirubinemia in Term and Late Preterm Babies

    • Authors: Arpita Gupta, VN Tripathi, Rupa D Singh, Kiran Pandey
      Pages: 139 - 143
      Abstract: Arpita Gupta, VN Tripathi, Rupa D Singh, Kiran Pandey
      Astrocyte 2017 4(3):139-143
      Objectives: To study the course and prediction of significant hyperbilirubinemia in healthy late preterm and term newborns. Material and Methods: Study comprises of 150 neonates: 92 term newborns and 58 late preterm neonates, each with birth weight >2000g, without Rh or ABO incompatibility or G6PD deficiency. A thorough clinical examination with biochemical measurement of serum bilirubin was done in both groups serially at 6th hour of birth, 2nd day of life, 3rd day, 4th day and on 7th day respectively and the pattern of rise of serum bilirubin and development of significant hyperbilirubinemia were compared in both groups. Results: Out of total 150 neonates, significant hyperbilirubinemia requiring phototherapy or exchange transfusion was noted in 28 patients (18.6%); 12 were term (13%) and 16 were late preterm babies (27.5%) i.e. late preterm babies were 2 times more likely to develop significant hyperbilirubinemia. Conclusion: Since late preterm babies are more vulnerable than their term counterparts, to the complications associated in early life especially hyperbilirubinemia, special attention is required in treating these babies.
      Citation: Astrocyte 2017 4(3):139-143
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_80_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Childhood Atopic Dermatitis: Impact on Quality of Life in Thai Children
           and their Families

    • Authors: Wanee Wisuthsarewong, Rattanavalai Nitiyarom, Niorn Boonpuen
      Pages: 144 - 148
      Abstract: Wanee Wisuthsarewong, Rattanavalai Nitiyarom, Niorn Boonpuen
      Astrocyte 2017 4(3):144-148
      Aim: To assess the impact of atopic dermatitis (AD) on quality of life (QoL) and the factor affecting QoL in Thai children and their families. Materials and Methods: This cross-sectional study was conducted on 86 AD patients at Siriraj Hospital. AD patients aged <16 years and their families were asked to complete the Thai versions of the Infants' Dermatitis Quality of Life Index (IDQoL), Children's Dermatology Quality of Life Index (CDLQI), and Dermatitis Family Impact Questionnaire (DFI). Results: Mean age of the patients was 6.5 ± 0.5 years old and 67.4% were females. The mean ± SD of QoL scores affected by AD was 8.88 ± 5.65. QoL score was high in the group of questions related to symptoms and feelings, followed by sleep problems. The mean ± SD score for DFI was 9.94 ± 7.49. Impact on QoL in Thai children and their families was significantly correlated with disease severity (P = 0.03, r = 0.24; and P= 0.01, r = 0.30, respectively). Factors that caused negative impact on QoL of patients were taking oral medications and disease severity (P = 0.01). Factors causing negative impact on QoL of families were disease severity (P = 0.01), positive for family member with allergic diseases (P= 0.01), start attending school (P = 0.02), and taking oral medications (P = 0.04). Limitation: The limitation of the study was the disadvantage of questionnaire-based study in collecting data. Conclusions: AD caused significant impact on QoL of Thai children and their families. QoL measurement should be included in the patient care assessment to improve effective management of AD.
      Citation: Astrocyte 2017 4(3):144-148
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_27_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • 99mTc-Pertechnetate Scintigraphy in Thyroid Gland Ectopia: Evolving a New
           Clinical Algorithm

    • Authors: Kalpa J Das, Ravinder S Sethi, Padma A Namgyal, Aditi K Sehgal
      Pages: 149 - 153
      Abstract: Kalpa J Das, Ravinder S Sethi, Padma A Namgyal, Aditi K Sehgal
      Astrocyte 2017 4(3):149-153
      Introduction: Dual ectopic thyroid has been regarded as a rare developmental anomaly with the most common site being lingual/sublingual and the mode of presentation being hypothyroidism. Patients and Methods: Three patients suffering from dual ectopic thyroid are discussed here along with a review of Indian literature. Conclusion: Increasing reports of dual ectopic thyroid in the literature indicate that the entity might not be so uncommon. Since this is liable to influence the clinical management, especially from the surgical standpoint, thyroid scintigraphy must be included in the preoperative protocol in all cases of thyroid gland ectopia.
      Citation: Astrocyte 2017 4(3):149-153
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_28_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Cutaneous Leishmaniasis in Nonendemic Geographic Areas: Unraveling the
           Itinerant Cases

    • Authors: Sandeep Arora, Aradhana Sood, Rajeshwari, Sukriti Baveja, Gulhima Arora, Ajay Malik, Rakesh Mishra
      Pages: 154 - 158
      Abstract: Sandeep Arora, Aradhana Sood, Rajeshwari , Sukriti Baveja, Gulhima Arora, Ajay Malik, Rakesh Mishra
      Astrocyte 2017 4(3):154-158
      Background: Cutaneous leishmaniasis endemic in 70 countries worldwide and in certain regions of India is otherwise an uncommon presentation in non-endemic zones, leading to their missed diagnosis. Movement of people between these regions further exposes them to the risk of this infection. The aim of this study was to analyze the presentation of these missed cases, basis of their final diagnosis, management and follow up with the objective of highlighting cutaneous leishmaniasis as an important differential diagnosis in these cases. Methods: A prospective 4-year cohort of patients who were diagnosed as cutaneous leishmaniasis (CL) and post kala azar dermal leishmaniasis (PKDL) between 2012 and 2016 were studied. Their presentation, basis of diagnosis, treatment response to different agents and follow up was studied. Results: Of a total of 380547 patients seen in the four-year period, 15 CL and 2 PKDL symptomatic from 6 months to 7 years were diagnosed at our centre. Leishmania amastigotes were seen in smears in 10 and 4 in skin biopsy. Four were diagnosed based on polymerase chain reaction for Leishmania. Ten were managed with iv Sodium Stibogluconate (SSG), five with intralesional SSG and one with liposomal amphotericin B. All responded to treatment and were followed up for one year thereafter. Conclusion: Although CL and PKDL are rare outside their endemic zones, travelers and population exposed to newer endemic zones may result in atypical presentations which clinicians are not experienced with. This study highlights this possibility and our experience in diagnosing and treating such cases.
      Citation: Astrocyte 2017 4(3):154-158
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_41_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Clinical Significance of High Resolution Ultrasonography vis-à -vis
           Laryngoscopy in Laryngeal Pathologies

    • Authors: Anil K Rai, Sandeep Trehan, MK Mittal, Gul Motwani
      Pages: 159 - 163
      Abstract: Anil K Rai, Sandeep Trehan, MK Mittal, Gul Motwani
      Astrocyte 2017 4(3):159-163
      Introduction: Larynx is a seat of a host of benign and malignant conditions. Conventionally, otolaryngologists have relied upon laryngoscopy in making a diagnosis. However, this simple doctor's office tool suffers from several limitations and flaws. In such a clinical landscape, a completely nonintrusive high-resolution ultrasonography examination can play a significant complementary role by defining the precise extent of the pathologic process. This prospective cross-sectional study, possibly the first of its kind in India, endeavours to define this synergetic relationship. Patients and Methods: A total of 60 patients with diverse undiagnosed laryngeal pathologies were taken up for the study. Those with proven laryngeal carcinoma and (or) past laryngeal surgery were excluded. Results: HRUS was found to be valuable in detecting laryngeal growth (78.57%), vocal cord polyp (66.67%), vocal cord nodule (10%), vocal cord palsy/paresis (66.67%), chronic laryngitis (17.64%), and Reinke's edema (50%). Conclusion: Compared to laryngoscopy, the role of HRUS is limited except in laryngeal lesions such as laryngeal growth and vocal cord polyp. HRUS can augment rather than replace conventional laryngoscopy in the diagnosis of laryngeal lesions.
      Citation: Astrocyte 2017 4(3):159-163
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_81_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Low dose Metronomic Chemotherapy in Patients of Acute Myeloid Leukemia

    • Authors: Gajendrapal Singh, Akash Mathur, Naincy Rastogi, Hemant Malhotra
      Pages: 164 - 168
      Abstract: Gajendrapal Singh, Akash Mathur, Naincy Rastogi, Hemant Malhotra
      Astrocyte 2017 4(3):164-168
      Background: Standard aggressive treatment of AML is expensive, requires significant supportive care (blood and platelet support) and toxic with significant morbidity and mortality. The metronomic approach refers to repetitive low doses of chemotherapy drugs and serves as one of the options of treatment for the patients who are unable to arrange the supportive care and those who are ineligible for intensive chemotherapy. Material and Methods: This is a hospital based observational single arm pilot study in which newly diagnosed 36 patients of AML who were unable to take standard aggressive chemotherapy were started on low dose metronomic chemotherapy and its effects evaluated over a period of 12 months. Results: Observed overall response rate (OR) was 21.87% (6.25% CR and 15.62% PR), mean survival was 3.58 months. 43.75% patients had non-hematological drug toxicities, 40.62% patients developed hematological toxicity, 3.12% developed hepatotoxicity and 9.32% patients developed febrile illness. Out of expired patients at the end of 1 year duration 70% died at their home with cause of death unidentified however rest 30% died in hospital (23% from bleeding and 7% from infection). On FACT-L questionnaire overall improvements were elicited in well being along with 43% improvement in additional concerns (including night sweats, pains, weight loss, tiredness). Conclusion: Data from our small study suggests that oral PEM metronomic chemotherapy for patients of AML with treatment possible on OPD basis itself appears to be an effective regimen with acceptable toxicities.
      Citation: Astrocyte 2017 4(3):164-168
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_53_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Airway Management in Maxillofacial Injuries: Identifying Clinical
           Determinants requiring Non-Conventional Strategies

    • Authors: Habib Md Reazaul Karim, Md Yunus
      Pages: 169 - 173
      Abstract: Habib Md Reazaul Karim, Md Yunus
      Astrocyte 2017 4(3):169-173
      Aim: Airway management in maxillofacial injuries is challenging. Conventionally, the method of securing the airway is using Macintosh laryngoscope to intubate the patients. Knowing the clinical variables associated with the need for nonconventional (nonMacintosh) laryngoscopy will aid in better airway management. The present analysis was aimed to identifying the clinical variables associated with nonconventional tracheal intubation in patients with maxillofacial injury. Materials and Methods: Medical records of maxillofacial injury patients with at least one facial bone fracture who needed tracheal intubation from January 2009 to June 2016 in a teaching institute were screened for data collection. The clinicodemographic parameters, techniques, and instruments used for tracheal intubation were noted. The INSTAT software was used for statistical analysis, and P < 0.05 was considered significant. Results: Seventy-three patients (mean age 27.47 ± 9.92 years; 94.52% male) were analyzed. A total of 61.64% of tracheal intubations required nonconventional techniques [i.e. video laryngoscope (27.4%), fiberoptic bronchoscope (26.03%), tracheostomy (6.85%), and 1.37% retrograde intubation]. Video laryngoscopy was preferred over Macintosh in patients with confirmed/suspected C-spine injury. Mouth opening <2 cm [odds ratio (OR): 7.33], multiple facial bone fracture (OR: 4.80), and concomitant mandible and maxilla fractures (OR: 6.50) were associated with tracheal intubation by nonconventional laryngoscopy (P = 0.01). Conclusion: Multiple facial bone fractures, concomitant mandible and maxilla fracture, and mouth opening <2 cm need tracheal intubation using a technique other than Macintosh laryngoscopy.
      Citation: Astrocyte 2017 4(3):169-173
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_11_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Central nervous system tuberculosis: Rare presentations of a common
           disease

    • Authors: Venkatram Krishnan, Mahesh Kumar Mittal, Mukul Sinha, Manohar Kumar, Brij Bhushan Thukral
      Pages: 174 - 185
      Abstract: Venkatram Krishnan, Mahesh Kumar Mittal, Mukul Sinha, Manohar Kumar, Brij Bhushan Thukral
      Astrocyte 2017 4(3):174-185
      Tuberculosis (TB) is a highly prevalent disease in developing countries of the world such as India. Central nervous system (CNS) involvement by TB can produce devastating effects and can be parenchymal, meningeal, intraventricular, subdural, or extradural. Common modes of CNS involvement include leptomeningitis and intracranial tuberculomas. Similar involvement of the spinal cord can produce tubercular arachnoiditis and intramedullary spinal tuberculomas. Atypical locations of tuberculomas include basal ganglia, brainstem, corpus callosum, and extra-axial and suprasellar locations. Uncommon modes of CNS involvement include tubercular pachymeningitis, focal tubercular cerebritis, cerebral abscess formation, and miliary TB. Tubercular pachymeningitis can also involve the dural lining of the spinal cord. We have presented cases of CNS TB, both atypical forms of common presentations as well as uncommon presentations with findings on magnetic resonance imaging (MRI) presenting a diagnostic dilemma. The radiologist plays a central role in the diagnosis of CNS TB in such cases, and careful tailoring of the MRI examination based on the clinical picture of the patient can play a vital role in making the diagnosis, even in atypical presentations.
      Citation: Astrocyte 2017 4(3):174-185
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_71_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Bronchogenic carcinoma masquerading as lung abscess

    • Authors: Vidushi Rathi, Pranav Ish, Gulvir Singh, SN Gaur
      Pages: 186 - 188
      Abstract: Vidushi Rathi, Pranav Ish, Gulvir Singh, SN Gaur
      Astrocyte 2017 4(3):186-188
      Lung abscesses are necrotizing consolidation of lung parenchyma which usually require a prolonged course of antibiotics. However, underlying secondary etiologies of lung abscess such as malignancy should be sought for, especially in unresponsive cases. Clinicoradiological correlation often assists, however, bronchoscopy and histopathology eventually confirm the diagnosis. We present a case of lung abscess who after initial response to antibiotics was subsequently diagnosed as squamous cell carcinoma of the lung.
      Citation: Astrocyte 2017 4(3):186-188
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_1_18
      Issue No: Vol. 4, No. 3 (2018)
       
  • Renal sinus lipomatosis in transplant kidney

    • Authors: Ankita Aggarwal, Aishwarya Gulati, Parveen Gulati
      Pages: 189 - 191
      Abstract: Ankita Aggarwal, Aishwarya Gulati, Parveen Gulati
      Astrocyte 2017 4(3):189-191
      Renal sinus lipomatosis is a rare entity where there is abnormal proliferation of sinus fat. Fat proliferation can also occur in perinephric and periureteric regions. It is a benign condition which does not give rise to symptoms or any renal impairment. However, severe form of this condition, i.e. renal replacement lipomatosis, leads to atrophy of renal parenchyma, thereby leading to impairment of renal functions. Here, we report a case of renal sinus lipomatosis in a transplanted kidney, which is even rarer and has been reported in less than 10 previously reported cases in the English literature.
      Citation: Astrocyte 2017 4(3):189-191
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_74_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Miliary tuberculosis with bilateral recurrent pneumothoraces

    • Authors: Omkar K Choudhari, Sonam Spalgais, Umesh Chandra Ojha, Amit Kumar Murar, Anand Kumar Verma
      Pages: 192 - 194
      Abstract: Omkar K Choudhari, Sonam Spalgais, Umesh Chandra Ojha, Amit Kumar Murar, Anand Kumar Verma
      Astrocyte 2017 4(3):192-194
      A 13-year girl presented with fever, chest pain, cough, and decreased appetite of 15 days. General and respiratory examination was normal. Routine investigations were normal. Sputum for AFB was negative. Chest X-ray revealed bilateral miliary nodules. Eye examination showed choroid tubercles with chorioretinitis. She was diagnosed as disseminated TB and started on ATT daily regime with oral prednisolone. After 5 days, she developed pneumothorax and ICD was inserted. CECT chest showed bilateral multiple miliary nodules with bilateral pneumothorax. She had recurrence (6 times) of Pneumothoraces during 3 months and managed with ICD. She underwent thoracoscopic surgical biopsy for confirmation of diagnosis. Immunohistocytology was negative for CD1a and HMB45. Biopsy was consistent with TB. The final diagnosis was miliary tuberculosis with bilateral recurrent Pneumothoraces. ATT continue for 9 months with tapering of steroid. Chemical pleurodesis was performed. She was followed up for 2 years with no recurrent of pneumothorax. Bilateral recurrent pneumothorax is rare complication of miliary TB.
      Citation: Astrocyte 2017 4(3):192-194
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_58_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Percutaneous retrieval of a fractured chemoport

    • Authors: Varun V Nivargi, Vihita Kulkarni, CN Makhale
      Pages: 195 - 197
      Abstract: Varun V Nivargi, Vihita Kulkarni, CN Makhale
      Astrocyte 2017 4(3):195-197
      Chemoport, a central venous infusion system, is commonly used in cancer patients for administration of chemotherapy. Dislodgement with subsequent migration of chemoport catheter in to the heart is a rare but potentially catastrophic complication. The treatment of choice is immediate retrieval of the dislodged part of catheter by surgery or percutaneous approach. Percutaneous removal is safer and less invasive making it the standard treatment modality. We report the case of a 9-year-old child who was referred to us for the management of a dislodged chemoport catheter.
      Citation: Astrocyte 2017 4(3):195-197
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_29_17
      Issue No: Vol. 4, No. 3 (2018)
       
  • Simultaneous balloon dilatation of subglottic stenosis and device closure
           of a large patent ductus arteriosus in infancy

    • Authors: Anil K Singhi, N VK Mohan, Chirajit Dutta, Anupama S Satpathy, Ashok Mittal, Amiya Mishra
      Pages: 198 - 200
      Abstract: Anil K Singhi, N VK Mohan, Chirajit Dutta, Anupama S Satpathy, Ashok Mittal, Amiya Mishra
      Astrocyte 2017 4(3):198-200
      Anatomic obstruction of the tracheobronchial tree in a patient with large posttricuspid shunt is rare and causes significant respiratory symptoms. The treatment of such patients is challenging. Here, we discuss and highlight the importance of detailed evaluation, planning, and teamwork for minimally invasive treatment of two major causes of respiratory distress. Hospital record analysis of a young infant who underwent simultaneous minimally invasive therapy for both cardiac and tracheal lesions. A 7-month-old infant weighing 4.4 kg had very large patent ductus arteriosus (PDA), along with heart failure and severe subglottic stenosis. She underwent successful minimally invasive balloon dilatation of subglottic stenosis followed by transcatheter device closure of PDA. Minimally invasive therapy for subglottic stenosis and device closure of PDA in a small infant is a safe and effective treatment in a well-planned and coordinated team approach.
      Citation: Astrocyte 2017 4(3):198-200
      PubDate: Tue,30 Jan 2018
      DOI: 10.4103/astrocyte.astrocyte_22_17
      Issue No: Vol. 4, No. 3 (2018)
       
 
 
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